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MATSUDA TakeruGraduate School of Medicine / Faculty of Medical SciencesAssociate Professor
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■ Paper- Anticancer Research USA Inc., Dec. 2024, Anticancer Research, 44(12) (12), 5485 - 5493Scientific journal
- Elsevier BV, Dec. 2024, Journal of Gastrointestinal Surgery, 101934 - 101934Scientific journal
- Elsevier BV, Dec. 2024, Journal of Gastrointestinal Surgery, 28(12) (12), 2001 - 2007Scientific journal
- Abstract Background Esophagectomy with lymphadenectomy is the primary treatment for esophageal squamous cell carcinoma (ESCC). However, intensive dissection of lymph nodes (LNs) along the recurrent laryngeal nerve (RLN) is associated with RLN palsy and pulmonary complications leading to poor survival. Therefore, this study aimed identify the risk factors for LNs metastasis along the RLN in patients with ESCC. Methods The present study included 168 patients with lower thoracic esophageal and esophagogastric junction (EGJ) squamous cell carcinoma who underwent esophagectomy with total mediastinal lymphadenectomy at Kobe University Hospital. Left/Right cervical paraesophageal (101 L/R), left/right recurrent nerve (106 recL/R), and left tracheobronchial LNs (106 tbL) were defined as LNs along the RLN. We evaluated the pathological distance between the proximal tumor boundary and the EGJ using images of the fixed specimen (PB‐EGJ length). Results LN metastasis along the RLN was observed in 19 (11%) patients. The percentage of patients with a longer PB‐EGJ length and cLNs metastasis was higher in the LNs metastasis along the RLN positive‐group than in the RLN‐negative group (p = 0.0075 and p = 0.013, respectively). The incidence of LNs metastasis along the RLN was 0% (95% confidence interval [CI] = 0–7.7%) when the PB‐EGJ length was <4 cm. Univariate analysis showed that patients with cLNs metastasis negative had a low risk for LNs metastasis along the RLN (odds ratio = 0.26 and 95% CI = 0.083–0.82). Conclusions Patients with a PB‐EGJ length <4 cm and negative for cLNs metastasis may be candidates for the omission of lymphadenectomy along the RLN.Wiley, Nov. 2024, World Journal of SurgeryScientific journal
- Abstract Developmental cyst is occasionally seen in children but are less common in adults. Complete removal of developmental cyst is necessary because there are risk of infection, squamous cell carcinoma, and recurrence due to incomplete resection. The best approach for resection of developmental cyst is still controversial. Although transsacral approach, open abdominal approach, or a combination of both have been often employed to date, reports of laparoscopic surgery have been appearing in recent years. We performed laparoscopic surgery for four patients with this disease: (i) 29‐year‐old woman with epidermoid cyst; (ii) 21‐year‐old woman with dermoid cyst; (iii) 55‐year‐old woman with epidermoid cyst; and (iv) 77‐year‐old woman with epidermoid cyst. No perioperative complications occurred and no recurrence has developed so far in any patients. Laparoscopic surgery can be considered as one of the optimal treatment options for developmental cyst.Wiley, Nov. 2024, Asian Journal of Endoscopic Surgery, 18(1) (1)Scientific journal
- (株)医学書院, Oct. 2024, 臨床外科, 79(11) (11), 119 - 124, Japanese
- Lead, Springer Science and Business Media LLC, Sep. 2024, Surgery TodayScientific journal
- Springer Science and Business Media LLC, Sep. 2024, Esophagus, 22(1) (1), 59 - 67Scientific journal
- Springer Science and Business Media LLC, Jun. 2024, Surgery TodayScientific journal
- Abstract Background Herein, we report a case of gastric antrum cancer with multiple invasions to other organs that was completely cured with laparoscopic distal gastrectomy after preoperative chemotherapy in a patient with poor general condition. Case presentation An 80-year-old male patient was diagnosed with anemia during follow-up for cerebral lacunar infarction at another hospital. He was diagnosed with advanced-stage gastric antrum cancer and was referred to our hospital. On esophagogastroduodenoscopy, type 2 advanced-stage gastric cancer was detected at the greater curvature of the antrum, and the biopsy results revealed tubular adenocarcinoma. Contrast-enhanced computed tomography scan revealed multiple invasions to other organs, thick gastric wall with contrast effect, and superior mesenteric vein tumor thrombus. However, there was no evidence of distant metastasis on positron emission tomography/computed tomography scan. The clinical diagnosis was stage IVA gastric cancer. Pancreatoduodenectomy with portal vein resection could be important at this point. However, preoperative chemotherapy with S-1 and oxaliplatin was administered instead of performing extended surgery because the patient had poor general condition (performance status score of 3). The patient received three cycles of preoperative chemotherapy at the hospital along with rehabilitation and nutritional management with oral nutritional supplements. After treatment, the performance status score of the patient improved from 3 to 1. Furthermore, in terms of clinical therapeutic effect, the patient achieved partial response. Hence, laparoscopic distal gastrectomy with D2 lymph node dissection and partial transverse colectomy was performed. After surgery, the patient was admitted for oral intake on postoperative day 6 and was discharged on postoperative day 21. Based on the histopathological examination, gastric cancer had disappeared, and there were no evident malignant findings. Therefore, gastric cancer was classified as grade 3 according to the histological treatment efficacy criteria. The patient did not present with recurrence at 2 years after surgery. Conclusions By actively administering preoperative chemotherapy, minimally invasive radical surgery with maximum preservation of the surrounding organs can be performed for locally far advanced-stage gastric cancer in older patients with poor general condition.Springer Science and Business Media LLC, Jun. 2024, Surgical Case Reports, 10(1) (1)Scientific journal
- Springer Science and Business Media LLC, Jun. 2024, Langenbeck's Archives of Surgery, 409(1) (1)Scientific journal
- Springer Science and Business Media LLC, May 2024, Surgical Endoscopy, 38(7) (7), 3625 - 3635Scientific journal
- Background In Japan, preoperative adjuvant chemotherapy followed by surgical resection is the standard treatment for patients with locally advanced esophageal squamous cell carcinoma. However, the risk of recurrence after surgical resection remains high. Although a randomized controlled trial evaluating the efficacy of nivolumab, a fully human monoclonal anti-programmed death 1 antibody, as postoperative adjuvant therapy after neoadjuvant chemoradiotherapy and surgery established its superior efficacy as adjuvant therapy, the efficacy for patients who received preoperative adjuvant chemotherapy has not been demonstrated. This study aims to elucidate the efficacy and safety of nivolumab as postoperative adjuvant therapy for patients with esophageal squamous cell carcinoma after preoperative adjuvant chemotherapy with docetaxel and cisplatin plus 5-fluorouracil followed by surgical resection. Methods This study is a multi-institutional, single-arm, Phase II trial. We plan to recruit 130 esophageal squamous cell carcinoma patients, who have undergone preoperative adjuvant chemotherapy with docetaxel and cisplatin plus 5-fluorouracil followed by surgical resection. If the patient did not have a pathological complete response, nivolumab is started as a postoperative adjuvant therapy within 4–16 weeks after surgery. The nivolumab dose is 480 mg/day every four weeks. Nivolumab is administered for up to 12 months. The primary endpoint is disease-free survival; the secondary endpoints are overall survival, distant metastasis-free survival, and incidence of adverse events. Discussion To our knowledge this study is the first trial establishing the efficacy of nivolumab as postoperative adjuvant therapy for patients with esophageal squamous cell carcinoma after preoperative adjuvant chemotherapy with docetaxel and cisplatin plus 5-fluorouracil followed by surgical resection. In Japan, preoperative adjuvant chemotherapy followed by surgery is a well-established standard treatment for resectable, locally advanced esophageal squamous cell carcinoma. Therefore, developing an effective postoperative adjuvant therapy has been essential for improving oncological outcomes.Public Library of Science (PLoS), Apr. 2024, PLOS ONE, 19(4) (4), e0299742 - e0299742Scientific journal
- (一社)日本消化器外科学会, Feb. 2024, 日本消化器外科学会雑誌, 57(2) (2), 67 - 74, Japanese
- Background/Aim: The relationship between gastric cancer and oral health has been reported in several studies. This study aimed to determine the relationship between the postoperative prognosis of gastric cancer and oral health using preoperative tooth loss as a simple index. Patients and Methods: We conducted a single-center retrospective cohort study. Patients were divided into two groups according to the number of tooth losses. The survival curve was constructed using the Kaplan–Meier method. We also performed univariate and multivariate analyses of overall survival based on Cox proportional hazard regression to determine prognostic factors. Results: A total of 191 patients were divided into two groups: those with seven or more tooth losses and those with less than seven tooth losses. The three-year overall survival rate was 71.5% in the group with seven or more tooth losses and 87.0% in the group with less than seven tooth losses. The group with seven or more tooth losses had a significantly lower overall survival rate compared to the group with less than seven tooth losses (p=0.0014). However, in multivariate analysis, tooth loss was not identified as an independent prognostic factor whereas age, clinical T stage, CEA level, and serum albumin level were independent poor prognostic factors. Conclusion: Preoperative tooth loss was not a prognostic factor for gastric cancer after gastrectomy, but tooth loss may be a simple and useful method for evaluating frailty in patients.Anticancer Research USA Inc., Jan. 2024, Cancer Diagnosis & Prognosis, 4(1) (1), 51 - 56Scientific journal
- Anticancer Research USA Inc., Dec. 2023, Anticancer Research, 44(1) (1), 229 - 237Scientific journal
- Springer Science and Business Media LLC, Dec. 2023, Annals of Surgical Oncology, 31(4) (4), 2482 - 2489Scientific journal
- Springer Science and Business Media LLC, Dec. 2023, Surgery TodayScientific journal
- (株)癌と化学療法社, Dec. 2023, 癌と化学療法, 50(13) (13), 1370 - 1373, Japanese
- (株)癌と化学療法社, Dec. 2023, 癌と化学療法, 50(13) (13), 1374 - 1377, Japanese
- Anticancer Research USA Inc., Nov. 2023, Anticancer Research, 43(12) (12), 5649 - 5656Scientific journal
- Abstract There has been no reliable marker for predicting oncological outcomes in patients with locally advanced rectal cancer (LARC) undergoing neoadjuvant chemoradiotherapy (NACRT). We retrospectively analyzed 73 patients with LARC who underwent curative surgery after NACRT. The modified Glasgow prognostic score (mGPS) was assessed after NACRT, and clinical outcomes were compared between the high (mGPS = 1 or 2; n = 23) and low (mGPS = 0; n = 50) groups. Body mass index was significantly higher in the low mGPS group. The 5-year disease-free survival (DFS) rate was significantly worse in the high mGPS group than that in the low mGPS group (36.7% vs. 76.6%, p = 0.002). Univariate and multivariate analyses of DFS revealed that mGPS was the most significant predictor (p < 0.001). mGPS appears to be a reliable predictor of oncological outcomes in patients with LARC undergoing NACRT.Springer Science and Business Media LLC, Oct. 2023, Scientific Reports, 13(1) (1)Scientific journal
- BACKGROUND/AIM: In pathology, the digitization of tissue slide images and the development of image analysis by deep learning have dramatically increased the amount of information obtainable from tissue slides. This advancement is anticipated to not only aid in pathological diagnosis, but also to enhance patient management. Deep learning-based image cytometry (DL-IC) is a technique that plays a pivotal role in this process, enabling cell identification and counting with precision. Accurate cell determination is essential when using this technique. Herein, we aimed to evaluate the performance of our DL-IC in cell identification. MATERIALS AND METHODS: Cu-Cyto, a DL-IC with a bit-pattern kernel-filtering algorithm designed to help avoid multi-counted cell determination, was developed and evaluated for performance using tumor tissue slide images with immunohistochemical staining (IHC). RESULTS: The performances of three versions of Cu-Cyto were evaluated according to their learning stages. In the early stage of learning, the F1 score for immunostained CD8+ T cells (0.343) was higher than the scores for non-immunostained cells [adenocarcinoma cells (0.040) and lymphocytes (0.002)]. As training and validation progressed, the F1 scores for all cells improved. In the latest stage of learning, the F1 scores for adenocarcinoma cells, lymphocytes, and CD8+ T cells were 0.589, 0.889, and 0.911, respectively. CONCLUSION: Cu-Cyto demonstrated good performance in cell determination. IHC can boost learning efficiencies in the early stages of learning. Its performance is expected to improve even further with continuous learning, and the DL-IC can contribute to the implementation of precision oncology.Aug. 2023, Anticancer research, 43(8) (8), 3755 - 3761, English, International magazineScientific journal
- Aug. 2023, Journal of the American College of Surgeons, 237(2) (2), 396 - 396, English, International magazine
- BACKGROUND/AIM: Colorectal cancer (CRC) with reduced expression of the homeobox transcription factor CDX2, a master gene essential for the development and maintenance of the intestinal tract, is known as a poor prognosis subtype of CRC. The recurrence rate is high in patients with CDX2low CRC. However, the prognostic significance of CDX2 in advanced CRC is unclear. This study aimed to elucidate the prognostic significance of CDX2 in unresectable metastatic CRC (mCRC). PATIENTS AND METHODS: Twenty-nine patients with unresectable mCRC who underwent primary site resection at the Kobe University Hospital during a 6-year period from January 2008 to January 2015 were included. The tissues from those patients were immunohistochemically stained with anti-CDX2 antibody (clone: CDX2-88). The patients were divided into CDX2high CRC group and CDX2low CRC group and their prognoses were analyzed. RESULTS: There were no clear differences in background between the two groups. A low CDX2 expression was associated with reduced overall survival (37.67 months vs. 25.32 months, p=0.03) and tended to associate with reduced progression-free survival (17.4 months vs. 12.9 months, p=0.37). Two patients received chemotherapy after resection of the primary lesion and obtained pathological complete response. CONCLUSION: CDX2 expression might be a possible prognostic biomarker for unresectable mCRC.Aug. 2023, Anticancer research, 43(8) (8), 3763 - 3767, English, International magazineScientific journal
- PURPOSE: Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. In recent years, the proportion of patients diagnosed with CRC at younger ages has increased. The clinicopathological features and oncological outcomes in younger patients with CRC remain controversial. We aimed to analyze the clinicopathological features and oncological outcomes in younger patients with CRC. METHODS: We examined 980 patients who underwent surgery for primary colorectal adenocarcinoma between 2006 and 2020. Patients were divided into two cohorts: younger (< 40 years old) and older (≥ 40 years old). RESULTS: Of the 980 patients, 26 (2.7%) were under the age of 40 years. The younger group had more advanced disease (57.7% vs. 36.6%, p = 0.031) and more cases beyond the transverse colon (84.6% vs. 65.3%, p = 0.029) than the older group. Adjuvant chemotherapy was administered more frequently in the younger group (50% vs. 25.8%, p < 0.01). Relapse-free survival and overall survival were similar between the groups at all stages. Moreover, in stages II and III they were also comparable, regardless of the administration of adjuvant chemotherapy. CONCLUSIONS: Younger patients with CRC have a prognosis equivalent to that of older patients. Further studies are needed to establish the optimal treatment strategies for these patients.Jul. 2023, International journal of colorectal disease, 38(1) (1), 191 - 191, English, International magazineScientific journal
- Jul. 2023, Annals of surgical oncology, 30(7) (7), 4056 - 4057, English, International magazineScientific journal
- BACKGROUND: Retrosternal reconstruction has lower risks for severe postoperative morbidities, such as gastro-tracheal fistula or esophageal hiatal hernia. We have previously reported the laparoscopic retrosternal route creation (LRRC) method, but its safety and efficacy remain unclear. METHODS: In total, 374 patients with esophageal carcinoma who underwent minimally invasive McKeown esophagectomy in the prone position between 2010 and 2021 were retrospectively reviewed. We performed a propensity score-matched analysis with the simple, nearest-neighbor method and no calipers to compare postoperative outcomes and reconstructed gastric conduit functionality between patients who underwent LRRC and counterparts who underwent posterior mediastinal reconstruction. RESULTS: After matching, 62 patients were included in the laparoscopic retrosternal group (LR group) or posterior mediastinal group (PM group). No significant differences were observed between the groups, apart from the number of robot-assisted surgeries, the extent of lymph node dissection, and the method of cervical anastomosis. There were no significant differences in the incidence of Clavien-Dindo grade ≥ 2 complications. Gastro-tracheal fistula (n = 1) and esophageal hiatal hernia (n = 2) occurred in the PM group but not in the LR group. There were no differences in the incidence of pulmonary embolism between the groups (5% vs. 5%). The postoperative anastomotic stenosis rate was similar (16% vs. 27%, p = 0.192). Endoscopic findings of reflux esophagitis (modified Los Angeles classification ≥ M) at 1 year after surgery were significantly better in the LR group (p = 0.037). CONCLUSIONS: LRRC for gastric conduit reconstruction is safe and valuable. It is associated with good reconstructed gastric conduit function.Jul. 2023, Annals of surgical oncology, 30(7) (7), 4044 - 4053, English, International magazineScientific journal
- BACKGROUND/AIM: There are several concerns about oncological contamination and technical difficulty in the laparoscopic approach for locally advanced gastric cancer. We aimed to determine the safety and usefulness of laparoscopic gastrectomy for patients with advanced gastric cancer with tumor depth greater than serosal invasion. PATIENTS AND METHODS: Sixty-two laparoscopic and 82 laparotomy gastric cancer cases surgically diagnosed as serosal or other organ invasions intraoperatively between 2011 and 2021 were included. The laparoscopic and open gastrectomy results were compared by propensity score matching using stage, preoperative chemotherapy, curative resection, surgical technique, and age as explanatory variables and laparoscopy and open resection as outcome variables. RESULTS: No difference in median operative time (341 vs. 386 minutes, p=0.24) was observed, but median blood loss (0 vs. 510 ml, p<0.001) and blood transfusion requirement (9.5 vs. 43%, p<0.001) were lower in the laparoscopic group. No difference was observed between the two groups regarding complications. Furthermore, 3-year overall survival was also similar (43 vs. 42%, p=0.74). CONCLUSION: The laparoscopic surgery results are comparable to those of open surgery in treating gastric cancer with T4a or greater depth. In addition, it is minimally invasive with less blood loss, making it a standard approach.Jul. 2023, Anticancer research, 43(7) (7), 3145 - 3152, English, International magazineScientific journal
- BACKGROUND: The effect of lymphadenectomy around the recurrent laryngeal nerve (RLN) in open oesophagectomy was demonstrated with the Efficacy Index (EI). However, it remains unclear whether this effect exists for minimally invasive esophagectomy (MIE) in the prone position. The purpose of this study is to clarify the upper mediastinal lymphadenectomy contributes to improved prognosis in patients with esophageal squamous cell carcinoma. STUDY DESIGN: This study included 339 patients with esophageal squamous cell carcinoma treated with MIE in the prone position at Kobe University or Hyogo Cancer Center from 2010 to 2015. EI for each station, correlations between metastatic L/Ns around the left RLN and RLN palsy, and survival of patients with and without upper mediastinal lymphadenectomy were investigated. RESULTS: Among 297 patients treated with upper mediastinal lymphadenectomy, Clavien- Dindo grade > II left RLN palsy occurred in 59 patients (20%). Overall, EIs for the right RLN (7.4) and left RLN (6.6) were higher than EIs for other stations. For patients with upper-third or middle-third tumors, the trend was stronger. Left RLN palsy was more likely in patients with metastatic L/Ns around the left RLN than in those without (44% vs. 15%, P < 0.0001).After propensity score-matching, 42 patients were included in each group with and without upper mediastinal lymphadenectomy. In survival analyses, the 5-year overall survival (OS) were 55% vs. 35% and cause-specific survival (CSS) rates were 61% vs. 43% for the patients with and without upper mediastinal lymphadenectomy respectively. Significant differences were confirmed in survival curves (OS; P = 0.03 and CSS; P = 0.04, respectively). CONCLUSIONS: Upper mediastinal lymphadenectomy contributes to improved prognosis with high EIs in MIE in the prone position.Jun. 2023, Journal of the American College of Surgeons, English, International magazineScientific journal
- Jun. 2023, Annals of surgical oncology, 30(6) (6), 3803 - 3804, English, International magazineScientific journal
- BACKGROUND: Although transanal total mesorectal excision (TaTME) is a promising treatment for low rectal cancer, it is considered technically demanding, and the number of cases required to become proficient in TaTME remains unknown. The purpose of this study was to assess the TaTME learning curve based on the total mesorectal excision completion time. STUDY DESIGN: This retrospective analysis comprised 128 individuals who received TaTME between September 2016 and December 2021. The cumulative sum method was used to generate the learning curve. The duration of the procedure from the beginning to the end of the circumferential rendezvous was used to define the total mesorectal excision completion time. RESULTS: The learning curve consists of 3 phases: phase I (learning phase: cases 1 to 38), phase II (consolidation phase: cases 39 to 70), and phase III (maturing phase: cases 71 to 128). As the phases varied, both the overall operative time and total mesorectal excision completion time decreased considerably. Through the 3 phases of TaTME, intraoperative adverse events decreased, and in phase III, none occurred. Only 1 instance of local recurrence occurred during phase III, and none occurred during phase I or II. CONCLUSIONS: After 70 operations, the surgeon could join the mastery phase of TaTME based on the total mesorectal excision completion time. After the mastering phase began, there were no intraoperative negative occurrences. From the beginning, the oncological safety could be guaranteed.May 2023, Journal of the American College of Surgeons, 236(5) (5), 1054 - 1063, English, International magazineScientific journal
- PURPOSE: Narrow pelvis, tumor diameter, and obesity have been reported as clinical variables correlated with the difficulty of conventional laparoscopic low anterior resection (Lap-LAR). A two-team transanal total mesorectal excision (TaTME) approach where the transabdominal and TaTME are performed simultaneously might reduce the difficulty associated with these factors. This study aimed to clarify the factors associated with the longer time required for TME (TME time) in conventional Lap-LAR and a two-team approach for TaTME. METHODS: We analyzed 52 patients with rectal carcinoma treated with Lap-LAR and 35 patients treated with TaTME. We performed simple linear regression analysis to assess the association between TME time and bony pelvic size using 3D pelvimetry, longest tumor diameter, and body mass index (BMI). RESULTS: Linear regression analysis demonstrated a highly significant association between TME time and obstetric conjugate (R2 = 0.098, P = .024) and BMI (R2 = 0.307, P < .001) in the Lap-LAR group, while no significant association was observed in the TaTME group. Male patients, who had a narrower bony pelvis and higher BMI than female patients, had longer TME time than female patients in the Lap-LAR group (213 minutes vs 172 minutes, P = .021), while the TME time of male and female patients did not differ in the TaTME group (122 minutes vs 108 minutes, P = .451). The TME time in the TaTME group was significantly shorter than that in the Lap-LAR group (121 minutes vs 197 minutes, P < .001). CONCLUSION: A two-team TaTME approach provided a shorter TME time compared to conventional Lap-LAR, regardless of pelvic size and BMI.Apr. 2023, Asian journal of endoscopic surgery, 16(2) (2), 189 - 196, English, Domestic magazineScientific journal
- BACKGROUND: Esophagectomy for esophageal carcinoma is associated with higher morbidity and mortality rates than other gastrointestinal surgeries. Smoking is an established risk factor for postoperative complications after esophagectomy. This study aimed retrospectively to investigate the impact of smoking status on short- and long-term outcomes for patients undergoing thoracoscopic esophagectomy in the prone position (TEP) for esophageal carcinoma. METHODS: In this study, 234 patients with esophageal carcinoma who underwent TEP between 2012 and 2020 were divided into two groups based on smoking status (current or non-current smokers and the Brinkman index) by patients' declarations. Postoperative complications (Clavien-Dindo classification grade ≥2), overall survival (OS), and disease-free survival (DFS) were compared between smoking statuses. RESULTS: The rates of postoperative complications did not differ significantly between the two groups (current smoker vs non-current smoker; Brinkman index ≥800 vs <800). The rate of postoperative pneumonia was higher in the combination group of current and higher Brinkman index (≥800) smokers than in the other group (25.0 % vs 11.8 %; P = 0.036). Multivariate analysis showed that smoking status was an independent risk factor for postoperative pneumonia (hazard ratio, 0.41; 95 % confidence interval, 0.18-0.93; P = 0.037). According to the long-term outcomes, no significant differences in OS and DFS were observed between the smoking statuses. CONCLUSIONS: The combination of current smoking and heavy smoking history is a risk factor for postoperative pneumonia in patients who have esophageal carcinoma treated with TEP, although no correlation was observed between the long-term outcomes and smoking status.Apr. 2023, Annals of surgical oncology, 30(4) (4), 2202 - 2211, English, International magazineScientific journal
- PURPOSE: Laparoscopic surgery for low rectal cancer is often challenging. Transanal total mesorectal excision (TaTME) and robotic surgery have been introduced to overcome the technical difficulties in laparoscopic surgery and achieve more favorable outcomes. Hybrid robotic surgery, which combines TaTME with the abdominal robotic approach, incorporates the advantages of each of these surgical techniques and might achieve less invasive and safer surgery. This study evaluated the safety and feasibility of hybrid robotic surgery with TaTME (hybrid TaTME). METHODS: We retrospectively reviewed 162 TaTME cases performed at our department from September 2016 to May 2022. Among them, 92 cases of conventional TaTME and 30 of hybrid TaTME were eligible. We used propensity score matching analysis (PSM) to adjust for patients' characteristics and compared the short-term outcomes of the two treatment groups. RESULTS: Twenty-seven cases in each group were extracted using PSM. The operation time in hybrid TaTME was comparable to that in conventional TaTME. There was no significant difference in the postoperative hospital stay between the two groups. Other intra- and post-operative outcomes were also comparable between the two groups. Furthermore, no significant differences were observed between the two groups in the curative resection and recurrence rates. CONCLUSION: Hybrid TaTME for low rectal cancer was as favorable as conventional TaTME in producing satisfactory short-term outcomes. However, furthermore, larger-scale studies conducted over longer study periods are needed to evaluate the validity of the findings.Mar. 2023, Langenbeck's archives of surgery, 408(1) (1), 129 - 129, English, International magazineScientific journal
- PURPOSE: This study aimed to compare motions of the laparoscope tip during a laparoscopic task in a training box using a recent joystick-guided robotic scope holder to those manipulated by human scopists. We hypothesized that laparoscopic manipulation could be positively affected by robotic scope holders due to the elimination of unintentional movement. METHODS: Twelve surgeons participated as operators, and eight medical doctors participated in this study. Among the human scopists, five were trained surgeons and three were novices who had no experience with laparoscopic surgery. A validated laparoscopic task was used to evaluate the path length of the laparoscope tip using an optical position tracker and operative time. The operators performed the designated camera task under three different laparoscopic manipulations: using a joystick-guided robotic scope holder, expert human scopists, and novice scopists. RESULTS: The median path lengths (cm) of the laparoscopic tip were 94.0, 110.0, and 122.2 in the robotic scope holder, expert, and novice groups, respectively. The path lengths in the robotic scope holder group were significantly shorter than those in the other groups (P < .01). The median operative times (seconds) were 136.6, 66.4, and 62.3 in the robotic scope holder, expert, and novice groups, respectively. The operative time of the robotic scope holder group was significantly longer than that of the other groups (P < .001). CONCLUSION: A robotic scope holder can provide shorter camera movement owing to the stable holding and intentional scope manipulation by the operator, although it requires a longer operative time than a human assistant.Feb. 2023, Surgical innovation, 15533506231157039 - 15533506231157039, English, International magazineScientific journal
- BACKGROUND: Although lateral pelvic lymph node dissection (LLND) might be an effective approach for patients with rectal cancer with lateral lymph node metastasis, it is technically challenging because of the anatomical complexity and location of the deep pelvis. An assistance by transanal approach might be useful for a successful LLND. METHODS: From September 2016 to May 2021, 39 patients with low rectal cancer underwent transanal total mesorectal excision with LLND. Among them, 18 patients underwent LLND using a conventional laparoscopic approach alone, while the remaining 21 underwent LLND using both conventional and transanal approaches. Their clinical outcomes were retrospectively compared. RESULTS: The operation time for LLND on each side was significantly shorter in the transanal group (105 min vs. 54 min, P < 0.001). The intraoperative blood loss was also significantly less in the transanal group (40 g vs. 0 g, P = 0.031). The rate of overall postoperative complications ≥ grade II according to the Clavien-Dindo classification was significantly less in the transanal group (66.7% vs. 28.6%, odds ratio: 5.000, 95% confidence intervals: 1.313-19.047, P = 0.040). The number of harvested lateral lymph nodes in both groups was similar (8.5 vs. 8, P = 0.544). CONCLUSION: The transanal approach for LLND reduced operative time, blood loss, and morbidity compared with the conventional approach alone in a cohort of patients with rectal cancer.Feb. 2023, Surgical endoscopy, 37(2) (2), 1562 - 1568, English, International magazineScientific journal
- Although a therapeutic response to neoadjuvant chemoradiotherapy (NACRT) is important to improve oncological outcomes after surgery in patients with locally advanced rectal cancer, there is no reliable predictor for this. The Wnt/β-catenin signal is known to be crucial for the tumorigenesis of colorectal cancer. This study aimed to investigate the association of Wnt/β-catenin signal activation with a pathological response to NACRT. The immunohistochemical expression of nuclear and membranous β-catenin was analyzed in biopsy samples obtained from 60 patients with locally advanced rectal cancer who received curative surgery following NACRT. The association of Wnt/β-catenin signal activation with their clinical outcomes was investigated. Notably, the body mass index of these patients was significantly higher in the low nuclear β-catenin expression group. Moreover, patients in the high nuclear β-catenin expression group tended to have more advanced disease and a higher rate of positive vascular invasion than those in the low expression group. Furthermore, the rate of good histological responses was significantly higher in the low nuclear β-catenin expression group (72% vs. 37.1%, p < 0.01). Overall, relapse-free survival tended to be better in patients with low nuclear/high membranous β-catenin expression (n = 9) than in other individuals (n = 51) (p = 0.093 and p = 0.214, respectively). Activation of the Wnt/β-catenin signal pathway represented by nuclear β-catenin accumulation was significantly associated with a poor response to NACRT in patients with rectal cancer. Analysis of nuclear β-catenin accumulation before starting treatment might help predict the therapeutic response to NACRT.Jan. 2023, Biomedicines, 11(1) (1), English, International magazineScientific journal
- PURPOSE: Rectal or anal canal adenocarcinoma with inguinal lymph node metastasis (ILNM) is rare and is associated with poor prognostic outcomes. This study aimed to elucidate the clinical significance of neoadjuvant therapy followed by selective inguinal lymph node dissection and total mesorectal excision for rectal or anal canal adenocarcinoma with clinically suspected ILNM. METHODS: This study enrolled 15 consecutive patients who underwent neoadjuvant therapy and curative resection for rectal or anal canal adenocarcinoma with clinically suspected ILNM between 2005 and 2019 at a single institution. Inguinal lymph node dissection was selectively performed on the side of suspected metastasis before neoadjuvant therapy. Short- and long-term outcomes were retrospectively reviewed. RESULTS: Out of the15 patients, 11 were treated with neoadjuvant chemoradiation, three with chemotherapy, and one with chemoradiation followed by chemotherapy. Fluorodeoxyglucose (FDG)-positron emission tomography (PET) scans were performed after neoadjuvant therapy in 14 patients. Five patients had negative FDG accumulation in inguinal lymph nodes on FDG-PET scan, and their inguinal lymph nodes were also pathologically negative for metastasis. Of the nine patients who had positive FDG accumulation, four had pathologically positive inguinal lymph nodes. Seven patients (46.7%) had inguinal seroma postoperatively. Five-year-overall survival was 77.5%, and 5-year-relapse-free survival was 64.2%. No patient had a recurrence in the inguinal region. CONCLUSION: In patients with rectal or anal canal adenocarcinoma associated with clinical ILNM, radical resection with neoadjuvant therapy provides a good long-term survival.Dec. 2022, Langenbeck's archives of surgery, 408(1) (1), 2 - 2, English, International magazineScientific journal
- Obesity, a known risk factor for various types of cancer, reduces the number and function of cytotoxic immune cells in the tumor immune microenvironment (TIME). However, the impact of obesity on CD4+ T cells remains unclear. Therefore, this study aimed to clarify the impact of obesity on CD4+ T cells in the TIME. A tumor-bearing obese mouse model was established by feeding with 45% high-fat diet (HFD), followed by inoculation with a colon cancer cell line MC38. Tumor growth was significantly accelerated compared to that in mice fed a control diet. Tumor CD4+ T cells showed a significant reduction in number and an increased expression of programmed death-1 (PD-1), and decreased CD107a expression and cytokine such as IFN-γ and TNF-α production, indicating dysfunction. We further established CD4+ T cell-depleted HFD-fed model mice, which showed reduced tumor infiltration, increased PD-1 expression in CD8+ T cells, and obesity-induced acceleration of tumor growth in a CD4+ T cell-dependent manner. These findings suggest that the reduced number and dysfunction of CD4+ T cells due to obesity led to a decreased anti-tumor response of both CD4+ and CD8+ T cells to ultimately accelerate the progression of colorectal cancer. Our findings may elucidate the pathogenesis for poor outcomes of colorectal cancer associated with obesity.Dec. 2022, Cells, 12(1) (1), English, International magazineScientific journal
- (公財)上原記念生命科学財団, Dec. 2022, 上原記念生命科学財団研究報告集, 36, 1 - 5, JapaneseWntシグナル制御による新規直腸癌化学放射線療法開発
- (株)癌と化学療法社, Dec. 2022, 癌と化学療法, 49(13) (13), 1711 - 1713, Japanese
- [A Case of Pathological Complete Response after Conversion Surgery for HER2-Positive Advanced Gastric Cancer with Multiple Distant Metastases].The patient is a 70's man. Esophagogastroduodenoscopy and contrast-enhanced CT scan of the abdomen revealed gastric cancer, 2 liver metastases, and peritoneal dissemination. He was diagnosed with unresectable advanced gastric cancer and received 5 courses of chemotherapy(CapeOX plus T-mab). The primary tumor size had reduced, and liver metastases and peritoneal dissemination were not detectable, so laparoscopic distal gastrectomy and partial hepatectomy were performed. Histopathological findings revealed no viable cancer cells in either the primary tumor or the hepatic resection site, and the histological response was Grade 3. The patient has been recurrence-free for 6 months since the surgery. Even in Stage Ⅳ gastric cancer with multiple distant metastases, long-term survival may be expected by conversion surgery after response to chemotherapy.Dec. 2022, Gan to kagaku ryoho. Cancer & chemotherapy, 49(13) (13), 1711 - 1713, Japanese, Domestic magazineScientific journal
- PURPOSE: Despite the increasing incidence of adenocarcinoma of the esophagogastric junction, laparoscopic proximal gastrectomy with lower esophagectomy (PGLE) is not widely accepted owing to the lack of standardized reconstruction techniques. In this study, we developed a new reconstruction method named y-shaped overlap esophagogastric tube reconstruction, which reproduces an angle of His and a pseudo-fornix, to be used in laparoscopic transhiatal PGLE. This study aimed to determine the feasibility of this novel reconstruction method. METHODS: This retrospective study included the analysis of short- and mid-term surgical outcomes of 30 consecutive patients with Siewert type II esophagogastric junction adenocarcinoma who underwent laparoscopic PGLE with y-shaped overlap esophagogastric tube reconstruction from April 2015 to August 2020. A novel method was used to form a 6-cm pseudo-fornix and an angle of His using the distal esophagus and a long gastric tube. RESULTS: The median operation time was 369 min, and the median blood loss was 28 mL. The median follow-up period after surgery was 37 months. Although two patients experienced postoperative anastomotic leakage, none of the patients developed stenosis. One patient experienced moderate reflux symptoms, whereas four patients developed moderate reflux esophagitis based on the 1-year follow-up endoscopic examination; the condition of all patients could be efficiently controlled with medication. CONCLUSION: The short- and mid-term surgical outcomes of y-shaped overlap esophagogastric tube reconstruction reflected the feasibility of this simple technique and suggested its potential utility as a reconstruction alternative for Siewert type II tumors.Dec. 2022, Langenbeck's archives of surgery, 407(8) (8), 3915 - 3915, English, International magazineScientific journal
- BACKGROUND: Many patients with esophageal squamous cell carcinoma (ESCC) have obstructive ventilatory disorder (OVD), which is considered a risk factor for postoperative pneumonia. It has been reported that thoracoscopic esophagectomy in the prone position (TEP) is less invasive and is associated with fewer postoperative respiratory complications compared with open esophagectomy. This matched-cohort study aimed to elucidate the safety and oncologic outcomes of ESCC patients with OVD who undergo TEP. METHODS: In this matched-cohort study, 237 patients with ESCC who underwent TEP between 2010 and 2018 were divided into two groups based on forced expiratory volume in 1 s/forced vital capacity. Postoperative complications (Clavien-Dindo classification grade II or higher), overall survival (OS), and disease-free survival (DFS) were compared between the two groups. RESULTS: Based on their propensity scores, 75 patients with normal respiratory function (NRF) and 75 with OVD were selected. The rates of postoperative pneumonia were not significantly different between the two groups (NRF group vs OVD group: 18.7% vs 18.7%; P = 1.000). The rates of recurrent laryngeal nerve palsy and anastomotic leakage were also not significantly different (NRF group vs OVD group: 12.0% vs 18.7%, P = 0.365; 18.7% vs 18.7%, P = 1.000). The 5-year OS and DFS rates in the NRF vs OVD groups were 66.2% vs 54.9% and 63.5% vs 52.9%, respectively, with no significant differences (P = 0.421, 0.197). CONCLUSIONS: TEP can be safely performed on ESCC patients with OVD and can result in an oncological efficiency equal to that of the NRF group.Dec. 2022, Surgical endoscopy, 36(12) (12), 8834 - 8842, English, International magazineScientific journal
- BACKGROUND/AIM: Although survival in cases with early recurrence after curative resection of colorectal cancer has been persistently poor, the risk factors for early recurrence remain unknown. PATIENTS AND METHODS: A total of 1,043 patients with stage I-III colorectal cancer underwent curative resection at Kobe University Hospital between April 2007 and September 2020. Of these, 122 patients developed recurrence: 57 had early recurrence (<1 year after surgery) and 65 patients had late recurrence (≥1 year after surgery). The clinicopathological features were compared between the groups and the risk factors for early recurrence were analyzed. RESULTS: Overall survival both from the date of recurrence and from the date of surgery were significantly worse in the early recurrence group. The proportion of the patients with ≥100 g of intraoperative blood loss, blood transfusion, and postoperative complications were significantly higher in the early recurrence group. R0 resection was achieved more frequently in the late recurrence group. Multivariate analysis revealed that no adjuvant chemotherapy, elevated preoperative CA19-9, blood transfusion, and the occurrence of the postoperative complication were independent risk factors for early recurrence. CONCLUSION: Early recurrence after curative resection of colorectal cancer was associated with worse overall survival. Adjuvant chemotherapy might be beneficial for patients with risk factors of early recurrence to improve prognosis.Nov. 2022, Anticancer research, 42(11) (11), 5553 - 5559, English, International magazineScientific journal
- PURPOSE: No study has focused on the safety and feasibility of our previously developed open-window suturing technique to close mucosal defects on the pancreatic side after endoscopic submucosal dissection from the opened duodenal wall. This study aimed to evaluate the safety and usefulness of laparoscopic endoscopic cooperative surgery for duodenal tumors for treating superficial non-ampullary duodenal epithelial tumors on the pancreatic side of the duodenum. METHODS: This retrospective study included 61 consecutive patients who underwent surgery during August 2014-November 2021. After dissection when the tumor was on the pancreatic side, we sutured the mucosal defect from the opened duodenal wall. A preoperative endoscopic pancreatic stent was placed for tumors within 1 cm of the ampulla of Vater. The surgical outcomes were compared between tumors on the pancreatic and non-pancreatic sides. RESULTS: There were 27 and 34 patients with tumors on the pancreatic and non-pancreatic sides, respectively. The patient characteristics were similar. Preoperative pancreatic stents were placed in four patients in the pancreatic side group. The median operative time was significantly longer on the pancreatic side than in the non-pancreatic side group (241 vs. 209 min, P = 0.02). In one patient in the pancreatic side group, an intraoperative injury of the ampulla of Vater was successfully treated with intraoperative management. There were no significant differences in the incidence of postoperative grade II or higher complications between the groups. CONCLUSIONS: Laparoscopic endoscopic cooperative surgery for duodenal tumors for treating superficial non-ampullary duodenal epithelial tumors on the pancreatic side is safe and feasible.Nov. 2022, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 26(11) (11), 2266 - 2273, English, International magazineScientific journal
- Oct. 2022, Annals of surgical oncology, 29(11) (11), 6867 - 6868, English, International magazineScientific journal
- BACKGROUND: Multidisciplinary treatment combining neoadjuvant treatment (NAT) and surgery has slightly improved the prognosis of patients with esophageal squamous cell carcinoma (ESCC). Although various biomarkers targeting nutrition and inflammation are associated with cancer prognosis, most studies have focused on conditions prior to NAT. Developing real-time and sensitive biomarkers that monitor changes in systemic conditions during NAT is important. We established a novel nutritional and inflammatory index, represented as the albumin to derived neutrophil-to-lymphocyte ratio (Alb-dNLR), and calculated the change in Alb-dNLR (ΔAlb-dNLR) during neoadjuvant chemotherapy (nCT). In this study, we aimed to evaluate whether ΔAlb-dNLR is associated with prognosis in patients with ESCC. METHODS: We investigated 172 patients who underwent nCT before esophagectomy between April 2010 and March 2018. The dNLR was calculated as the ratio of neutrophil count to (white blood cell count - neutrophil count), Alb-dNLR was calculated by dividing the serum albumin level by the dNLR, and ΔAlb-dNLR was evaluated by dividing the post-Alb-dNLR by the pre-Alb-dNLR. Patients were divided into 'high' and 'low' groups according to the ΔAlb-dNLR. RESULTS: Thirty-nine patients (22.7%) had a low ΔAlb-dNLR (≤ 0.8), and the 5-year overall survival (OS) rates in patients with low and high ΔAlb-dNLR were 38.1% and 53.6%, respectively (p = 0.0072). Multivariate analyses demonstrated that estimated blood loss (p = 0.044), pathological T stage (p = 0.0005), pathological N stage (p = 0.017), and ΔAlb-dNLR (p = 0.005) were independent prognostic factors for OS. CONCLUSIONS: ΔAlb-dNLR is a useful prognostic factor for OS in patients with ESCC receiving nCT.Oct. 2022, Annals of surgical oncology, 29(11) (11), 6860 - 6866, English, International magazineScientific journal
- Oct. 2022, Annals of surgical oncology, 29(11) (11), 6869 - 6870, English, International magazineScientific journal
- The risk factors for delayed gastric emptying (DGE) following gastrectomy are unclear. This study aimed to investigate the risk factors for DGE and the severity of DGE. We retrospectively evaluated 412 patients who underwent gastrectomy for gastric cancer between 2011 and 2019. The cases were classified into the DGE (n = 27) and non-DGE (n = 385) groups; the DGE group was further classified into two subgroups based on nasogastric tube insertion as an indicator of severity. For determining the relationship between resected stomach volume and DGE, we calculated the area of each surgical specimen using the ImageJ software. Female sex (odds ratio [OR] 2.55; 95% confidence interval [CI] 1.09-5.93; P = 0.03), diabetes (OR 2.38; 95% CI 1.02-5.57; P = 0.03), and distal gastric tumors (OR 2.61; 95% CI 1.10-6.19; P = 0.02) were identified as independent risk factors by multivariate analysis. The duration of hospital stay was longer in the DGE group than in the non-DGE group (29 vs. 15 days, P < 0.01). Overall, 24 cases of DGE (89%) were found in more than 1 week following surgery. No correlation was observed between clinical features and the severity of DGE. The resected area in the DGE group was significantly larger than that in the non-DGE group (198.0 vs. 173.9 cm2, P = 0.03). In conclusion, DGE was frequently observed in females and in patients with diabetes and distal gastric tumors. Most of the DGE cases occurred after 7-14 days of surgery, patients who are discharged early should be informed to seek hospitalization if they have symptoms caused by DGE.Sep. 2022, Scientific reports, 12(1) (1), 15903 - 15903, English, International magazineScientific journal
- BACKGROUND: The eighth edition of the American Joint Committee on Cancer (AJCC) tumor node metastasis (AJCC-TNM 8th) system adopted the newly separate post-neoadjuvant pathologic stage group (ypTNM). However, it is not compatible with the Japanese pathologic classification after neoadjuvant chemotherapy (JPN-CT-pTNM). The aim of this study is to clarify the subjects of the AJCC-ypTNM 8th and propose a unification of the AJCC and Japanese systems to create novel AJCC-CT-pTNM 8th. METHODS: Participants were 304 esophageal squamous cell carcinoma (ESCC) patients who underwent neoadjuvant chemotherapy followed by 3 stage esophagectomy between 2010 and 2019. Predictive probabilities of pN, pM in AJCC-ypTNM 8th and JPN-CT-pTNM 11th systems were evaluated to propose novel system. RESULTS: In training data from 234 patients, the overall survival rate was statistically better for ypStage IIIA than ypStage II (P = 0.040) resulting in staging inversion in AJCC-ypTNM 8th. Predictive probability of pathological N status in AJCC-ypTNM 8th (Akaike Information Criterion: AIC = 979.53) was superior to that in JPN-CT-pTNM 11th (AIC = 999.07). In AJCC-ypTNM 8th, 71% (15/21) of ypM1 diseases were supraclavicular lymph nodes (No. 104 L/N as regional in JPN-CT-pTNM 11th) metastases with considerably good prognosis. The predictive probability of the novel AJCC-CT-pTNM 8th [unification of ypStage II and IIIA, conversion of supraclavicular L/Ns metastases from ypM to ypN] (AIC = 1054.24) was superior to that of the existing AJCC-ypTNM 8th (AIC = 1070.74). The feasibility of novel system was validated using test data from 70 patients. CONCLUSIONS: Unification of the AJCC and Japanese systems yields a simpler and more precise predictive system after neoadjuvant chemotherapy.Aug. 2022, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 48(8) (8), 1760 - 1767, English, International magazineScientific journal
- PURPOSE: Despite the increasing incidence of adenocarcinoma of the esophagogastric junction, laparoscopic proximal gastrectomy with lower esophagectomy (PGLE) is not widely accepted owing to the lack of standardized reconstruction techniques. In this study, we developed a new reconstruction method named y-shaped overlap esophagogastric tube reconstruction, which reproduces an angle of His and a pseudo-fornix, to be used in laparoscopic transhiatal PGLE. This study aimed to determine the feasibility of this novel reconstruction method. METHODS: This retrospective study included the analysis of short- and mid-term surgical outcomes of 30 consecutive patients with Siewert type II esophagogastric junction adenocarcinoma who underwent laparoscopic PGLE with y-shaped overlap esophagogastric tube reconstruction from April 2015 to August 2020. A novel method was used to form a 6-cm pseudo-fornix and an angle of His using the distal esophagus and a long gastric tube. RESULTS: The median operation time was 369 min, and the median blood loss was 28 mL. The median follow-up period after surgery was 37 months. Although two patients experienced postoperative anastomotic leakage, none of the patients developed stenosis. One patient experienced moderate reflux symptoms, whereas four patients developed moderate reflux esophagitis based on the 1-year follow-up endoscopic examination; the condition of all patients could be efficiently controlled with medication. CONCLUSION: The short- and mid-term surgical outcomes of y-shaped overlap esophagogastric tube reconstruction reflected the feasibility of this simple technique and suggested its potential utility as a reconstruction alternative for Siewert type II tumors.Aug. 2022, Langenbeck's archives of surgery, 407(5) (5), 1881 - 1890, English, International magazineScientific journal
- In recent years, the usefulness of neoadjuvant chemotherapy for resectable advanced gastric cancer, particularly stage III, has been reported. Preoperative staging is mainly determined by computed tomography (CT), and the usefulness of 18F-fluoro-2-deoxyglucose positron emission tomography/CT (FDG-PET/CT) for gastric cancer has been limited in usefulness. The study aimed to evaluate the usefulness of FDG-PET/CT in preoperative diagnosis of advanced gastric cancer. We retrospectively enrolled 113 patients with gastric cancer who underwent preoperative FDG-PET/CT. All patients underwent gastrectomy with lymph-node dissection. The maximum standardized uptake value (SUVmax) of the primary tumor (T-SUVmax) and lymph nodes (N-SUVmax) were measured for all patients. The cutoff values of T-SUVmax for pathological T3/4 from receiver operating characteristic analysis were 8.28 for differentiated and 4.32 for undifferentiated types. The T-SUVmax and N-SUVmax cutoff values for pathological lymph-node metastasis were 4.32 and 1.82, respectively. Multivariate analysis showed that T-SUVmax for differentiated types was a significant predictor of pathological T3/4, and N-SUVmax was a significant predictor of lymph-node metastasis. In conclusion, the SUVmax of FDG-PET/CT was a useful predictor of pathological T3/4 and lymph-node metastasis in gastric cancer. The diagnosis by preoperative FDG-PET/CT is promising to contribute a more accurate staging of gastric cancer than by CT scan alone.Jul. 2022, Scientific reports, 12(1) (1), 11370 - 11370, English, International magazineScientific journal
- BACKGROUND: Postoperative complications affect long-term prognosis in patients with esophageal squamous cell carcinoma (ESCC). Although a comprehensive estimator can predict long-term prognosis, the Clavien-Dindo classification system, a widely used approach to evaluate complications, assesses each complication individually. We aimed to clarify the utility of the comprehensive complication index (CCI) on predicting the overall survival (OS) of patients with ESCC following minimally invasive esophagectomy (MIE). METHODS: This was a retrospective study of patients undergoing MIE for ESCC in the prone position between January 2011 and December 2018. Multivariate analyses using the Cox proportional hazards model were performed to determine independent risk factors for OS. RESULTS: The study cohort included 229 patients who were categorized into patients with CCI values of ≥ 33.7 (CCI high) and < 33.7 (CCI low) by receiver-operating characteristic (ROC) curve analysis. There were no significant differences between the two groups according to clinicopathological factors, such as sex, age, tumor location, tumor depth, lymph node metastasis, and neoadjuvant chemotherapy. The intraoperative transfusion rate in the CCI high group was significantly higher than in the CCI low group. The 5 year OS rate was significantly lower in the CCI high group than in the CCI low group (49.5% vs. 65.7%, p = 0.030). By multivariate analyses, age, tumor depth, lymph node metastasis, and the CCI were independent predictors of OS. CONCLUSIONS: Comprehensive assessment of postoperative complications using the CCI was useful in predicting OS of patients undergoing MIE for the ESCC.Jul. 2022, Esophagus : official journal of the Japan Esophageal Society, 19(3) (3), 410 - 416, English, Domestic magazineScientific journal
- BACKGROUND: Technical difficulties are occasionally encountered when performing conventional minimally invasive esophagectomy and robot-assisted minimally invasive esophagectomy in patients with a narrow thoracic cavity. Thoracic cavity-to-cage ratio is an indicator of thoracic cavity length. We hypothesized that the thoracic cavity-to-cage ratio could be a predictor of technical difficulties in conventional minimally invasive esophagectomy and robot-assisted minimally invasive esophagectomy. METHODS: We evaluated 340 patients who underwent minimally invasive esophagectomy for esophageal squamous cell carcinoma between April 2010 and March 2021. Thoracic cavity-to-cage ratio was calculated as the diameter of the thoracic cavity to that of the thoracic cage at the brachiocephalic vein, tracheal bifurcation, and inferior right pulmonary vein levels. Moreover, thoracic cavity-to-cage ratio score, which is an indicator of the whole thoracic cavity length based on the thoracic cavity-to-cage ratio at the 3 levels, was defined. The thoracic procedure time was considered an indicator of surgical difficulty. RESULTS: We divided the patients into the conventional minimally invasive esophagectomy (n = 295) and robot-assisted minimally invasive esophagectomy (n = 45) groups. The patients in each group were divided into 2 cohorts according to median thoracic procedure time. Based on multivariate analysis, body mass index (P = .0007), clinical N stage (P = .0191), and thoracic cavity-to-cage ratio score (P = .0005) were independent factors for thoracic procedure time in the conventional minimally invasive esophagectomy group. Moreover, thoracic cavity-to-cage ratio at the tracheal bifurcation level (P = .0331) was the only independent factor for thoracic procedure time in the robot-assisted minimally invasive esophagectomy group. CONCLUSION: Thoracic cavity-to-cage ratio could be a predictor of technical difficulties in both conventional minimally invasive esophagectomy and robot-assisted minimally invasive esophagectomy.Jul. 2022, Surgery, 172(1) (1), 145 - 149, English, International magazineScientific journal
- Jun. 2022, Ann Surg Oncol, 29(6) (6), 3683
- BACKGROUND: Minimally invasive esophagectomy (MIE) for esophageal cancer patients with sarcopenia is associated with a high risk of perioperative complications; however, the relationship between sarcopenia and the survival of esophageal cancer patients remains controversial. In this study, we aimed to develop a stratifying marker for sarcopenia to precisely predict patients' prognosis. METHODS: We retrospectively studied 135 patients who underwent thoracoscopic esophagectomy at Kobe University Hospital from 2011 to 2015 and who were preoperatively diagnosed with or without sarcopenia based on the Asian Working Group for Sarcopenia index. Creatinine levels and albumin as measures of skeletal muscle volume and nutritional status, respectively, were used to develop a marker to be used for stratifying sarcopenic patients based on prognosis. RESULTS: Of the 135 patients, 35 were diagnosed with sarcopenia and 100 were not. We combined the creatinine and albumin levels (Cr × Alb) as a stratifying marker for sarcopenia, and extracted sarcopenic patients with values below the Cr × Alb cut-off as the actual sarcopenic group. The 5-year overall survival (OS) rates of the actual and non-actual sarcopenic groups were 28.9% and 58.9%, respectively (p = 0.0005), and the 5-year disease-free survival rate of the actual sarcopenic group was 34.1%, and 62.8% (p = 0.0106) for the non-actual sarcopenic group. This stratified sarcopenia model was an independent prognostic factor and was superior to sarcopenia alone for OS. CONCLUSIONS: In patients undergoing MIE, preoperative measurement of Cr × Alb may be a prognostic stratification marker for patients with sarcopenia.Jun. 2022, Annals of surgical oncology, 29(6) (6), 3670 - 3681, English, International magazineScientific journal
- Although transperineal minimally invasive abdominoperineal resection (tp-APR) based on the concept of transanal total mesorectal excision has recently been used for rectal cancer, the operative procedure has not been standardized to date due to its technical difficulty. The tp-APR procedure used by the authors for a male patient with low rectal cancer is presented in this video.May 2022, Annals of surgical oncology, 29(5) (5), 3065 - 3065, English, International magazineScientific journal
- BACKGROUND/AIM: Esophageal squamous cell carcinoma (ESCC) is a deadly malignant disease. This study examined whether the platelet-to-lymphocyte ratio (PLR) can be used as a biomarker to evaluate prognosis in patients with advanced ESCC following neoadjuvant chemotherapy (NAC) and undergoing minimally invasive esophagectomy (MIE). PATIENTS AND METHODS: We examined 174 patients between January 2010 and December 2015 at the Kobe University. Of these, 121 were treated with NAC. The PLR cutoff was determined through receiver-operating characteristic curve analysis. Univariate and multivariate analyses were conducted to identify prognostic factors for overall survival (OS). RESULTS: The PLR cutoff for OS in 121 patients was 169.6. Patients with PLR ≥169.6 had worse 5-year OS rates (31.1%) than those with a PLR <169.6 (61.1%, p=0.001). Multivariate analysis revealed that a PLR of ≥169.6 was an independent factor for poor prognosis. CONCLUSION: PLR is an independent prognostic factor for patients with ESCC after NAC and MIE.May 2022, Anticancer research, 42(5) (5), 2775 - 2782, English, International magazineScientific journal
- May 2022, Surgical endoscopy, 36(5) (5), 3676 - 3676, English, International magazine
- BACKGROUND: Whether surgical device usage in laparoscopic gastrectomy differs with respect to operator's skill levels is unknown. Further, device usage analysis using artificial intelligence has not been reported to date. Herein, we compared the patterns of surgical device usage during laparoscopic gastrectomy for gastric cancer among surgeons at different skill levels. The data of device usage was acquired from laparoscopic video recordings using an automated surgical-instrument detection system. METHODS: In total, 100 video recordings of infrapyloric lymphadenectomy and 33 of D2 suprapancreatic lymphadenectomy during laparoscopic gastrectomy for gastric cancer were analyzed in this retrospective study. The system's accuracy was evaluated by comparing the automatic and the manual usage time. Surgical device usage patterns were compared between qualified and nonqualified surgeons of The Japan Society for Endoscopic Surgery Endoscopic Surgical Skill Qualification System. RESULTS: For every device, the automatic detection time and manual detection time were consistent with each other. In infrapyloric lymphadenectomy, the usage time proportions of dissector forceps and clip applier were higher among nonqualified operators than among qualified operators (dissector, 5.1% vs. 2.3%, P < 0.001; clip applier, 1.6% vs. 1.3%, P < 0.01). In suprapancreatic lymphadenectomy, the usage time proportions of energy devices, clip applier, and grasper forceps were significantly different (energy devices, 59.6% vs. 50.6%, P < 0.001; clip applier, 1.4% vs. 0.9%, P < 0.001; only grasper forceps; 18.3% vs. 27.9%, P = 0.022). CONCLUSIONS: Quantitative analysis of laparoscopic device usage using the automated surgical device detection system showed that the patterns of device usage during laparoscopic gastrectomy differed depending on surgeons' skill levels. These differences could suggest how the qualified and nonqualified surgeons performed the procedures.May 2022, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 26(5) (5), 1006 - 1014, English, International magazineScientific journal
- May 2022, Annals of surgical oncology, 29(5) (5), 3066 - 3066, English, International magazineScientific journal
- BACKGROUND: Retrosternal reconstruction is associated with a lower risk of mediastinitis, gastro-tracheal fistula, and hiatal hernia. Historically, traumatic manual creation of the retrosternal tunnel has been performed using one's fist. We report a novel and atraumatic laparoscopic procedure to create the retrosternal route. METHODS: We have laparoscopically created the retrosternal route in 25 thoracoscopic, mediastinoscopic, or robot-assisted minimally invasive esophagectomies since August 2019. Specifically, a peritoneal incision is started at the dorsal side of the xiphoid process. Through a 12-mm port inserted slightly to the right of and superior to the umbilical camera port, we dissect loose connective tissues from the caudal to the cranial side using behind the sternum and inside the internal thoracic vessels as landmarks. The time required to create the route was calculated. Then, the cumulative sum (CUSUM) method and the simple moving average of five cases were used to evaluate the learning curve of this novel procedure. Operative outcomes were analyzed according to the learning curve results and also compared with 25 cases of postmediastinal reconstruction counterparts. RESULTS: Twenty-five patients were divided into the early group (six patients) and late group (19 patients) based on the peak of the CUSUM chart. The time required for route creation was 28.5 min (median) in the early and 15 min in the late group, indicating a significant difference (P = 0.038). The overall incidence of pleural injury was 20% (5 of 25 patients), with no significant difference between the groups. There was no significant difference in the incidence of perioperative complications. Also, there were no significant differences in perioperative complications or gastric conduit functions 1 year after surgery between the retrosternal and the postmediastinal reconstruction. CONCLUSION: Laparoscopic creation of a retrosternal route for gastric conduit reconstruction is safe and feasible and has a short learning curve.Apr. 2022, Surgical endoscopy, 36(4) (4), 2680 - 2687, English, International magazineScientific journal
- INTRODUCTION: Recently, sarcopenia has been reported to be associated with poor postoperative outcomes in various cancers. However, its clinical significance for rectal cancer patients undergoing neoadjuvant chemoradiotherapy (NACRT) followed by surgery remains unknown. MATERIALS AND METHODS: This study included 46 patients with locally advanced rectal cancer who underwent curative surgery after NACRT. Sarcopenia was assessed by measuring the cross-sectional psoas muscle area (PA) at L3 and total bilateral psoas muscle volume (PV). Patients with a lower PV or PA value than the median were assigned to the sarcopenia group while others were assigned to the non-sarcopenia group. Clinical outcomes were then compared between groups. RESULTS: The sarcopenia group included 22 patients. The rate of overall postoperative complications did not differ between groups. Five-year relapse-free survival (RFS) was significantly lower in the sarcopenia group when sarcopenia was assessed by PV after NACRT (44.0% vs. 82.6%, P = 0.00494). In contrast, RFS did not differ between groups when sarcopenia was assessed by PA. Multivariable analysis identified PV after NACRT as the most significant risk factor for RFS (hazard ratio 4.00; 95% CI 1.27-12.66, P = 0.018). CONCLUSION: Sarcopenia assessed by total PV after NACRT may be an accurate and reliable predictor of poor oncological outcomes in rectal cancer patients.Apr. 2022, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 48(4) (4), 850 - 856, English, International magazineScientific journal
- BACKGROUND: Multidisciplinary treatment for esophageal squamous cell carcinoma (ESCC) has improved outcomes, but the prognosis for ESCC remains poor. Nutritional and inflammatory indicators are reported to be associated with cancer prognosis. The combination of albumin and the derived neutrophil-to-lymphocyte ratio (Alb-dNLR) score was established to measure the immune system and nutritional status. The authors hypothesized that the Alb-dNLR score could be a new reliable prognostic factor for ESCC patients. METHODS: The study evaluated 269 patients who underwent esophagectomy between April 2010 and March 2018, including 185 patients who received neoadjuvant chemotherapy. The Alb-dNLR score was calculated using serum albumin and the dNLR. The dNLR was calculated as neutrophils to (leukocyte-neutrophil count). The cutoff values of the albumin and dNLR for overall survival (OS) were determined using the receiver operating characteristic curve. Patients were divided into "high" and "low" groups according to the Alb-dNLR score. RESULTS: A high Alb-dNLR score was found in 61 cases (22.7%). The 5-year OS was 34% in the high Alb-dNLR group and 66.2% in the low Alb-dNLR group (p < 0.0001). The 5-year cause-specific survival (CSS) was 51.5% in the high Alb-dNLR group and 74.7% in the low Alb-dNLR group (p < 0.0001). Multivariate analyses demonstrated that the Alb-dNLR score was an independent prognostic factor for OS (hazard ratio [HR], 2.198; 95% confidence interval [CI], 1.460-3.263; p = 0.0002) and CSS (HR, 1.733; 95% CI, 1.035-2.835; p = 0.0371). CONCLUSIONS: The Alb-dNLR score is an extremely useful, easy-to-use parameter to predict OS and CSS for ESCC patients.Apr. 2022, Annals of surgical oncology, 29(4) (4), 2663 - 2671, English, International magazineScientific journal
- The functional near-infrared spectroscopy (fNIRS) can detect hemodynamic responses in the brain and the data consist of bivariate time series of oxygenated hemoglobin (oxy-Hb) and deoxygenated hemoglobin (deoxy-Hb) on each channel. In this study, we investigate oscillatory changes in infant fNIRS signals by using the oscillator decompisition method (OSC-DECOMP), which is a statistical method for extracting oscillators from time series data based on Gaussian linear state space models. OSC-DECOMP provides a natural decomposition of fNIRS data into oscillation components in a data-driven manner and does not require the arbitrary selection of band-pass filters. We analyzed 18-ch fNIRS data (3 minutes) acquired from 21 sleeping 3-month-old infants. Five to seven oscillators were extracted on most channels, and their frequency distribution had three peaks in the vicinity of 0.01-0.1 Hz, 1.6-2.4 Hz and 3.6-4.4 Hz. The first peak was considered to reflect hemodynamic changes in response to the brain activity, and the phase difference between oxy-Hb and deoxy-Hb for the associated oscillators was at approximately 230 degrees. The second peak was attributed to cardiac pulse waves and mirroring noise. Although these oscillators have close frequencies, OSC-DECOMP can separate them through estimating their different projection patterns on oxy-Hb and deoxy-Hb. The third peak was regarded as the harmonic of the second peak. By comparing the Akaike Information Criterion (AIC) of two state space models, we determined that the time series of oxy-Hb and deoxy-Hb on each channel originate from common oscillatory activity. We also utilized the result of OSC-DECOMP to investigate the frequency-specific functional connectivity. Whereas the brain oscillator exhibited functional connectivity, the pulse waves and mirroring noise oscillators showed spatially homogeneous and independent changes. OSC-DECOMP is a promising tool for data-driven extraction of oscillation components from biological time series data.Mar. 2022, PLoS computational biology, 18(3) (3), e1009985, English, International magazineScientific journal
- Mar. 2022, Diseases of the colon and rectum, 65(3) (3), e175, English, International magazineScientific journal
- BACKGROUND/AIM: This study aimed to examine the efficacy of surgical intervention after chemotherapy for stage IV gastric cancer and the predictors of survival after surgical intervention. PATIENTS AND METHODS: Forty-three gastric cancer patients who had only one type of incurable factor (e.g., para-aortic lymph node metastasis) and had undergone initial chemotherapy, underwent chemotherapy alone (CX group; n=25), palliative gastrectomy (PS group; n=8), and conversion surgery (CS group; n=10). Their therapeutic outcomes were compared. RESULTS: The CS group had significantly higher 2-year overall survival rates (80%) than the CX group (25%), whose prognosis was similar to that of the PS group (23%; p<0.001). Pathological complete response of para-aortic lymph node or peritoneal metastases was an independent predictor of survival after surgery, as was >6 months of chemotherapy. CONCLUSION: CS may improve the prognosis of patients with stage IV gastric cancer in whom chemotherapy can achieve pathological disappearance of the metastatic lesions.Mar. 2022, Anticancer research, 42(3) (3), 1541 - 1546, English, International magazineScientific journal
- BACKGROUND: This study aimed to identify prognostic factors for adenocarcinoma of the esophagogastric junction (AEG) in Siewert type II and characterize the population whose prognosis is expected to improve. PATIENTS AND METHODS: We retrospectively reviewed a database of 68 AEG type II patients who had undergone surgical curative resection without preoperative treatment. RESULTS: Although patients with pathological N0 (pN0) showed favorable 3-year disease-free survival (91%), patients with pN1-3 had poor outcomes (42%, 23%, and 10%). Multivariate analyses showed that the only independent prognostic factor was lymph node metastasis, and that tumor depth (cT3-4) and tumor size (≥4 cm) were correlated closely with lymph node metastasis. CONCLUSION: Surgical curative resection without preoperative treatment is insufficient to treat AEG type II with lymph node metastasis. Among AEG patients, those with the high-risk factors of preoperative tumor depth (T3-4) or/and size (≥4 cm) might need intensive multimodal treatment, including perioperative adjuvant chemotherapy.Feb. 2022, Anticancer research, 42(2) (2), 1051 - 1057, English, International magazineScientific journal
- PURPOSE: We conducted a prospective clinical control study to identify the best imaging technology among three-dimensional (3-D) high-definition (HD) stereovision and two-dimensional (2-D) ultra-high-resolution (4 K) technology and confirm their effects on surgical outcomes of laparoscopic gastrectomy for gastric cancer. METHODS: From April 2018 to August 2019, 50 patients were randomly classified into two groups based on the imaging technology (3-D/HD group = 25, 2-D/4 K = 25). After excluding eight patients based on laparoscopic findings, 42 patients were analyzed (3-D/HD group = 21, 2-D/4 K = 21). The primary endpoint was the operative time; the secondary endpoints were blood loss, postoperative infectious complications, and postoperative hospital stay. RESULTS: The patients' backgrounds were similar (sex, age, body mass index [BMI], stage, procedure, and extent of lymph node dissection). There were no significant differences in operative time (252 vs. 238 min, P = 0.70), total blood loss, postoperative infectious complications, and postoperative hospital stay between the two groups. However, video analysis of surgeries revealed a significantly shortened median operative time (18 vs. 25 min, P = 0.04) in the suturing step with 3-D/HD; the median number of camera cleaning procedures during suprapancreatic lymph node dissection was significantly lower with 2-D/4 K than with 3-D/HD (n = 4.4 vs. 2.8, P = 0.02). CONCLUSION: 3-D/HD and 2-D/4 K laparoscopic radical gastrectomies provide similar surgical outcomes. However, the 3-D monitor reduces suturing time during reconstruction, while the 4 K monitor reduces the number of camera cleaning procedures during lymphadenectomy. TRIAL REGISTRATION: Registered in the University Hospital Medical Information Network Clinical Trials Registry (identification number 000029227).Feb. 2022, Langenbeck's archives of surgery, 407(1) (1), 105 - 112, English, International magazineScientific journal
- Jan. 2022, Annals of surgical oncology, English, International magazineScientific journal
- BACKGROUND/AIM: The safety of gastrectomy for patients receiving antithrombotic agents remains unclear. This retrospective cohort study sought to compare outcomes between patients who did and did not receive antithrombotic agents. PATIENTS AND METHODS: This single-center retrospective cohort study included 548 patients who underwent gastrectomy for primary gastric adenocarcinoma from January 2011 to December 2019. The surgical outcomes were compared between two groups according to whether they received antithrombotic therapy (n=121) or not (n=427). RESULTS: Among the entire cohort, the patients in the antithrombotic therapy group were significantly older than those who did not receive this therapy and had significantly higher postoperative complication rates than those who did not (33.1% vs. 23.9%; p=0.046). However, after propensity score matching, no significant difference in the postoperative complication rate was observed between the two groups. CONCLUSION: Despite having a high risk for postoperative complications, patients receiving antithrombotic therapy can safely undergo gastric resection.2022, Cancer diagnosis & prognosis, 2(2) (2), 210 - 215, English, International magazineScientific journal
- Situs inversus totalis (SIT) is a rare condition in which the internal organ's position is a mirror image of normal anatomy. Although several investigators reported laparoscopic surgery for colorectal cancer in patients with SIT, it is considered difficult even for an experienced surgeon because of the mirror position. We show a case report of laparoscopic sigmoidectomy with the splenic flexure mobilization (SFM) procedure in SIT. A 79-year-old woman with SIT was referred to our hospital for a locally advanced sigmoid cancer (cT3N1M0, cStageIIIB). We safely performed the laparoscopic sigmoidectomy with SFM, as shown in detail below. No postoperative complication occurred, and the patient is in good health with no recurrences 30 months after surgery, as of the writing this report. We propose three critical points; checking the CT angiography to understand the anatomy; using flip-horizontal video of "normal" laparoscopic sigmoidectomy to confirm an unfamiliar situation; adding the epigastric trocar to make SFM procedures safe and comfortable.Jan. 2022, Asian journal of endoscopic surgery, 15(1) (1), 168 - 171, English, Domestic magazine
- (1) Background: Cancer vaccines are administered to induce cytotoxic CD8+ T cells (CTLs) specific for tumor antigens. Invariant natural killer T (iNKT) cells, the specific T cells activated by α-galactosylceramide (α-GalCer), play important roles in this process as they are involved in both innate and adaptive immunity. We developed a new cancer vaccine strategy in which dendritic cells (DCs) were loaded with an exogenous ovalbumin (OVA) protein by electroporation (EP) and pulsed with α-GalCer. (2) Methods: We generated bone marrow-derived DCs from C57BL/6 mice, loaded full-length ovalbumin proteins to the DCs by EP, and pulsed them with α-GalCer (OVA-EP-galDCs). The OVA-EP-galDCs were intravenously administered to C57BL/6 mice as a vaccine. We then investigated subsequent immune responses, such as the induction of iNKT cells, NK cells, intrinsic DCs, and OVA-specific CD8+ T cells, including tissue-resident memory T (TRM) cells. (3) Results: The OVA-EP-galDC vaccine efficiently rejected subcutaneous tumors in a manner primarily dependent on CD8+ T cells. In addition to the OVA-specific CD8+ T cells both in early and late phases, we observed the induction of antigen-specific TRM cells in the skin. (4) Conclusions: The OVA-EP-galDC vaccine efficiently induced antigen-specific antitumor immunity, which was sustained over time, as shown by the TRM cells.Dec. 2021, Cancers, 14(1) (1), English, International magazineScientific journal
- BACKGROUND: Despite the increasing utilization of transanal total mesorectal excision as a promising approach for low rectal cancer, the feasibility and safety of transperineal minimally invasive abdominoperineal resection (tp-APR) remain unclear. METHODS: In total, 25 patients who underwent tp-APR between April 2017 and May 2020 (tp-APR group) and 27 patients who underwent conventional laparoscopic APR between May 2009 and September 2016 (lap-APR group) for low rectal cancer were enrolled in this retrospective study. Clinical outcomes were compared between the groups before and after propensity score matching. The primary outcome was the incidence of the overall postoperative complications with Clavien-Dindo grade II or above. Standardized technique of tp-APR was also demonstrated. RESULTS: On comparison, operative time, intraoperative blood loss, and overall postoperative complications with Clavien-Dindo grade II or above were significantly less in the tp-APR group both before and after propensity score matching. The rates of urinary disturbance and perineal wound infection were significantly less in the tp-APR group after matching. Further, postoperative hospital stay was significantly shorter in the tp-APR group both before and after matching. However, pathological outcomes did not differ between the groups before and after matching. There has been no local recurrence in the tp-APR group with a median follow-up period of 18 months. CONCLUSION: Standardized tp-APR for low rectal cancer is feasible and seems superior to conventional laparoscopic APR in terms of short-term outcomes. Further larger-scale studies with a longer follow-up period are required to evaluate oncological outcomes.Dec. 2021, Surgical endoscopy, 35(12) (12), 7236 - 7245, English, International magazineScientific journal
- BACKGROUND: One of the primary treatment for resectable advanced esophageal squamous cell cancer (ESCC) is neoadjuvant chemotherapy (NAC) followed by minimally invasive esophagectomy (MIE). Because the neutrophil-to-lymphocyte ratio (NLR) is a widely reported prognostic factor in several cancers, we investigated whether the preoperative NLR is a biomarker in ESCC patients treated with NAC and MIE. METHODS: In this study, we investigated 174 ESCC patients who underwent MIE from January 2010 to December 2015, including 121 patients who received NAC. The cutoff value of the NLR was analyzed using the receiver operating characteristic curve. Multivariate analyses were performed to clarify independent prognostic factors for overall survival (OS). RESULTS: The cutoff value of the NLR for OS in 121 patients who received NAC was 2.5 ng/ml, and the area under the curve was 0.63026 (p = 0.0127). The 5-year OS rate was 64% in those with an NLR <2.5 and 39% in those with an NLR ≥2.5. According to multivariate analysis, NLR ≥2.5, pathological T, pathological N, and intraoperative blood loss of >415 ml were independent poor prognostic factors. CONCLUSIONS: NLR is a biomarker of prognosis in ESCC patients who undergo MIE after NAC.Dec. 2021, Journal of surgical oncology, 124(7) (7), 1022 - 1030, English, International magazineScientific journal
- INTRODUCTION: Although lateral pelvic lymph node dissection is considered as a treatment option for advanced rectal cancer, it is technically demanding. Recently, the transanal approach for total mesorectal excision has become increasingly used. In this Technical Note, we describe lateral pelvic lymph node dissection using a 2-team method that was assisted by the transanal approach. TECHNIQUE: First, the lateral pelvic area was entered from the anal side by dissection between the S4 sacral splanchnic nerve and levator ani muscle. Then, the fatty tissues including the obturator compartment and the distal part of the internal iliac compartment were separated from the inferior and superior vesical vessels and the bladder wall. Next, the fatty tissues were separated from the lateral pelvic wall. The obturator nerve was isolated and preserved, whereas the obturator vessels were resected at their peripheral end. Then, the fatty tissues were dissected from the bottom plane. Finally, the fatty tissues were dissected from the ventral bladder wall and were completely isolated from the obturator nerve in cooperation with the transabdominal team. RESULTS: The 2-team method shortened the operative time dramatically and decreased mental and physical burden on the operators during lateral dissection. Assistance with the transanal approach helped with a secure and effective dissection, especially of the most distal parts, such as around the internal pudendal and inferior vesical arteries, because substantial skill is required for the transabdominal approach alone. CONCLUSIONS: This procedure is useful for the safe and effective performance of lateral pelvic lymph node dissection for patients with rectal cancer.Dec. 2021, Diseases of the colon and rectum, 64(12) (12), e719-e724, English, International magazineScientific journal
- Nov. 2021, Annals of surgical oncology, 28(12) (12), 7258 - 7258, English, International magazineScientific journal
- BACKGROUND: Esophagectomy with lymphadenectomy is the principal treatment for localized esophageal cancer. Conventional minimally invasive esophagectomy (C-MIE) in prone position has spread worldwide as it is less invasive. However, its efficacy remains controversial. Robot-assisted MIE (RAMIE) can have more advantages than C-MIE. Therefore, the current study aimed to validate whether RAMIE is associated with lower incidence of left recurrent laryngeal nerve (RLN) palsy compared with C-MIE in prone position. PATIENTS AND METHODS: In total, 404 patients with esophageal carcinoma underwent MIE (353 C-MIEs and 51 RAMIEs) in prone position at Kobe University between 2010 and 2020. Then, propensity score matching was performed, and results showed that 51 patients should be included in each group. Thereafter, the perioperative outcomes between the two groups were compared. RESULTS: The RAMIE group had a significantly longer operative time than the C-MIE group (P < 0.0001). However, the number of lymph nodes resected along the left RLN was similar in both groups. Moreover, the incidence of left RLN palsy was significantly lower in the RAMIE group than in the C-MIE [Clavien-Dindo classification grade II; 0 (0%) versus 32 (9%), P = 0.022 in entire cohort, and 0 (0%) versus 5 (10%), P = 0.022 in matched cohort. Esophagectomy Complications Consensus Group definitions type I; 8 (16%) versus 101 (29%), P = 0.041 in entire cohort and 8 (16%) versus 18 (35%) in matched cohort, P = 0.023]. CONCLUSION: RAMIE is superior to C-MIE in prone position in decreasing the incidence of left RLN palsy.Nov. 2021, Annals of surgical oncology, 28(12) (12), 7249 - 7257, English, International magazineScientific journal
- PURPOSE: There has been an increase in the percentage of elderly patients with colorectal cancer (CRC). However, few studies have reported the short- and long-term outcomes of laparoscopic surgery for elderly patients with CRC aged over 80 years. METHODS: This study included 529 patients who underwent laparoscopic resection for clinical stage 0-III CRC at Kobe University Hospital between January 2010 and December 2018. Propensity score matching (PSM) was used to create balanced cohorts of the elderly (aged ≥ 80, n = 113) and the non-elderly (aged < 80, n = 113). Their clinical outcomes were compared after PSM. RESULTS: After matching, carcinoembryonic antigen (CEA) level was higher in the non-elderly group, and adjuvant chemotherapy was less frequently employed in the elderly group. D3 dissection was performed more frequently and the number of the harvested lymph nodes tended to be larger in the non-elderly group. There was no significant difference in the rates of postoperative complications, reoperation within 30 days, and 30-day mortality between the groups. The 5-year relapse-free survival rate was not statistically different between the two groups (77.3% for the non-elderly vs. 62.7% for the elderly, p = 0.13). The multivariate analyses for the whole cohort showed that the factors of sex, tumor location, operation time, and conversion to open surgery, but not the age, were significant predictors of postoperative complications. CONCLUSION: Laparoscopic surgery for colorectal cancer patients aged over 80 years is technically and oncologically safe.Nov. 2021, International journal of colorectal disease, 36(11) (11), 2519 - 2528, English, International magazineScientific journal
- BACKGROUND: Lateral pelvic lymph node metastasis impairs the oncological outcomes of patients with rectal cancer. Although lateral pelvic lymph node dissection (LLND) might be an effective procedure for such patients, the associated risk factors for postoperative complications are unknown. PATIENTS AND METHODS: The operative outcomes of 21 patients undergoing unilateral LLND and 26 patients undergoing bilateral LLND for rectal cancer were compared. The risk factors for complications were evaluated using a logistic regression model. RESULTS: Univariate and multivariate analyses revealed that a longer operative time (≥480 min) was the most important risk factor for grade II or more postoperative complications according to the Clavien-Dindo classification (odds ratio=6.58; 95% confidence interval=1.35-32.1; p=0.020). A bilateral procedure was not a significant risk factor for postoperative complications. CONCLUSION: Surgeons should make efforts to shorten the operative time to reduce the risk of postoperative complications.Nov. 2021, Anticancer research, 41(11) (11), 5599 - 5604, English, International magazineScientific journal
- Oct. 2021, Annals of surgical oncology, 28(11) (11), 6339 - 6340, English, International magazineScientific journal
- PURPOSE: Laparoscopic local resection for gastrointestinal stromal tumors (GISTs) near the esophagogastric junction (EGJ) increases the risk of injuring the EGJ. We investigated the safety of laparoscopic local resection for GISTs near the EGJ according to the distance from the EGJ to the tumor edge. METHODS: We retrospectively evaluated 40 patients who had undergone laparoscopic local resection for GISTs near the EGJ between January 2009 and December 2019. After excluding 1 patient who had undergone right colectomy at the same time, 39 patients were classified according to distance of the GIST from the EGJ in the Near group (0-2.0 cm; n = 16) and the Far group (2.1-5.0 cm; n = 23). RESULTS: We found no marked differences in the operation time, blood loss, length of postoperative hospital stay, or postoperative complication rate in the two groups. Anastomotic leakage occurred with a tumor located on the EGJ. Three tumors recurred in the Near group, and all of them were located on the EGJ. CONCLUSION: Except for GISTs located on the EGJ, laparoscopic local resection for GISTs near the EGJ can be performed safely with few postoperative complications and a low risk of recurrence.Jul. 2021, Surgery today, 52(3) (3), 395 - 400, English, Domestic magazineScientific journal
- 金原出版(株), Jul. 2021, 手術, 75(8) (8), 1259 - 1267, Japanese
- Aim: The outcomes of gastrectomy for gastric cancer in patients at each severity of chronic kidney disease (CKD) remain unknown. Methods: We retrospectively analyzed the outcomes of 560 patients who underwent distal or total gastrectomy for gastric cancer between 2009 and 2018. We classified the patients into four groups based on estimated glomerular filtration rate: stage 1/2 (normal to mild, n = 375), stage 3a (mild to moderate, n = 122), stage 3b (moderate to severe, n = 43), and stage 4/5 (severe to end-stage, n = 20) CKD. The relationship between CKD stage and the incidence of postoperative morbidity was analyzed. Results: CKD was a predictor of overall morbidity independent of age, gender, American Society of Anesthesiologists Performance Status, pulmonary comorbidity, extent of lymphadenectomy, and operation time in a multivariate analysis. The incidences of overall and severe morbidity were significantly increased with CKD progression (both P < .001). Compared to stage 1/2 CKD, the odds of overall morbidity were significantly elevated in stage 3a (odds ratio [OR] 1.87, P = .007), stage 3b (OR 3.86, P < .001), and stage 4/5 (OR 8.60, P < .001). The risk of procedure-related morbidity was strikingly increased in stage 3b (OR 2.93, P = .004). The risk of procedure-unrelated morbidity elevated markedly in stage 3a (OR 2.77, P = .001). A significant graded association between CKD progression and overall morbidity was also revealed in elderly patients (P = .001). Conclusions: The severity of CKD predicts the likelihood and type of morbidity after gastrectomy and can guide surgical decision-making for patients with gastric cancer.Jul. 2021, Annals of gastroenterological surgery, 5(4) (4), 519 - 527, English, Domestic magazineScientific journal
- BACKGROUND: Given the worldwide popularization of conventional minimally invasive esophagectomy (C-MIE), robot-assisted MIE (RAMIE) can be expected to provide a finer procedure. However, controversy remains regarding whether RAMIE is superior to C-MIE in preventing recurrent laryngeal nerve (RLN) palsy. Considering the shallow learning curve for RAMIE, a novel procedure for lymphadenectomy along the RLN during RAMIE is needed. METHODS: Based on a logical and simple understanding of the left upper mediastinum anatomy, the authors developed a novel "modified bascule method" for RAMIE that could simplify lymphadenectomy along the left RLN and prevent it from being touched and stretched. Between 2018 and 2020, 46 patients with esophageal carcinoma underwent RAMIE using this method at Kobe University. RESULTS: The modified bascule method was used to perform RAMIE for 29 men and 17 women with a median age of 67 years (range, 49-82 years). The median thoracoscopic procedure time was 438 min (range, 344-625 min), and the median console time was 351 min (range 273-518 min). The study harvested a median of 24 (range, 8-34) lymph nodes from the thoracic portion and 4 (range, 0-10) lymph nodes from along the left RLN. The mortality rate was 0%. Postoperative left RLN palsy classified as Clavien-Dindo (C-D) grade 1 or higher was observed for 9 patients (19%), whereas grade 2 or higher was not seen (0%). Pneumonia and anastomotic leakage rates higher than C-D grade 2 were respectively 13% and 19%. CONCLUSIONS: The novel modified bascule method for RAMIE can promote feasible lymphadenectomy along the left RLN even when performed during the learning period.Mar. 2021, Annals of surgical oncology, 28(9) (9), 4918 - 4927, English, International magazineScientific journal
- BACKGROUND/AIM: The safety of neoadjuvant chemoradiotherapy (NACRT) combined with total mesorectal excision (TME) and selective lateral pelvic lymph node dissection (LLND) is unclear in elderly patients with locally advanced rectal cancer (LARC). PATIENTS AND METHODS: Forty-two patients with LARC underwent TME and selective LLND following NACRT at Kobe University Hospital. The clinical outcomes were retrospectively compared between the elderly (aged ≥70 years, n=13) and non-elderly patients (aged <70, n=29). RESULTS: Twelve of the thirteen elderly patients could complete NACRT. Although the overall rate of postoperative complications did not differ between the groups, abdominal wound infection and deep vein thrombosis developed more frequently in the elderly group. The length of the postoperative hospital stay was similar. Three-year overall survival and 3-year relapse-free survival rates were similar between the groups. CONCLUSION: Selective LLND after NACRT is safe for elderly patients with LARC.Mar. 2021, Anticancer research, 41(3) (3), 1677 - 1682, English, International magazineScientific journal
- BACKGROUND: Esophageal squamous cell cancer (ESCC) is one of the deadliest cancers in the world. Esophagectomy remains the principal treatment, and minimally invasive esophagectomy (MIE) has been performed worldwide. This study aimed to clarify whether the lymph node ratio (LNR), defined as the ratio of metastatic lymph nodes (LNs) to examined, is a prognostic factor for ESCC after MIE. METHODS: This study included 327 MIEs with the patient in the prone position at two institutions from 2010 to 2015. Cox proportional hazards regression analyses using clinicopathologic characteristics and the LNR were performed for the pN1 patients and the whole cohort. RESULTS: In the multivariate analysis for all stages, independent prognostic factors were depth of tumor invasion (P < 0.0001), LNR (P = 0.014), operative time (P = 0.003), and pneumonia (P = 0.012). In the analysis of the pN1 subgroup, the optimum LNR cutoff level for overall survival (OS) was 9 based on receiver operation characteristic analysis. The LNR was significantly associated with depth of tumor invasion (P = 0.004) and number of metastatic LNs (P < 0.0001). The OS curve for the group with an LNR of 9 or higher was significantly worse than for the group with an LNR lower than 9 (P < 0.001). Multivariate analyses demonstrated that the LNR is a unique independent prognostic factor for the pN1 subgroup (hazard ratio, 6.811; 95% confidence interval, 2.009-23.087; P = 0.002). CONCLUSIONS: The LNR is an independent prognostic factor in ESCC after MIE. Especially for patients with pN1 status, the LNR is more useful than the number of metastatic LNs for predicting survival outcome.Jan. 2021, Annals of surgical oncology, 28(8) (8), 4519 - 4528, English, International magazineScientific journal
- CONTEXT: There is an increasing demand for appropriate preclinical mice models for evaluating the efficacy of cancer immunotherapies. AIMS: Therefore, we established a humanized patient-derived xenograft (PDX) model using microsatellite instability-high (MSI-H) colorectal cancer (CRC) tissues and patient-derived peripheral blood mononuclear cells (PBMCs). SUBJECTS AND METHODS: The CRC tissues of patients scheduled for surgery were tested for MSI status, and CRC tumors were transplanted into NOD/LtSz-scid/IL-2Rg-/-(NSG) mice to establish MSI-H PDX models. PDX tumors were compared to the original patient tumors in terms of histological and genetic characteristics. To humanize the immune system of MSI-H PDX models, patient PBMCs were injected through the tail vein. RESULTS: PDX models were established from two patients with MSI-H CRC; one patient had a germline mutation in MLH1 (c.1990-2A > G), and the other patient had MLH1 promoter hypermethylation. PDX with the germline mutation was histologically similar to the patient tumor, and retained the genetic characteristics, including MSI-H, deficient mismatch repair (dMMR), and MLH1 mutation. In contrast, the histological features of the other PDX from a tumor with MLH1 promoter hypermethylation were clearly different from those of the original tumor, and MLH1 promoter hypermethylation and MSI-H/dMMR were lost in the PDX. When T cells from the same patient with MLH1 mutation were injected into the PDX through the tail vein, they were detected in the PDX tumor. CONCLUSIONS: The MSI-H tumor with an MMR mutation is suitable for MSI-H PDX model generation. The PBMC humanized MSI-H PDX has the potential to be used as an efficient model for cancer immunotherapy research.2021, Journal of cancer research and therapeutics, 17(6) (6), 1358 - 1369, English, International magazineScientific journal
- BACKGROUND/AIM: Adenocarcinoma of the esophagogastric junction (AEG) is refractory even when curative resection is followed by adjuvant chemotherapy. This study evaluated the efficacy of neoadjuvant chemotherapy (NAC) using an oral fluoropyrimidine-platinum regimen for AEG. PATIENTS AND METHODS: Out of 35 patients with locally advanced AEG who underwent curative resection, 21 who underwent surgery first and 14 who received NAC were retrospectively compared in terms of survival. RESULTS: The NAC regimens comprised of S-1 or capecitabine plus oxaliplatin or cisplatin; trastuzumab was added to six borderline resectable cases. The downstaging rate was 50% and the pathological response rate including complete response (29%) was 50%. The three-year relapse-free survival in the NAC group was significantly superior than the surgery-first group (78% vs. 22%, p=0.011). The NAC group had a significantly longer median survival time than the surgery-first group (NR vs. 29 months, p=0.032). CONCLUSION: NAC using an oral fluoropyrimidine-platinum regimen may provide survival benefit in AEG.2021, Cancer diagnosis & prognosis, 1(3) (3), 185 - 191, English, International magazineScientific journal
- BACKGROUND: Patients often experience severe weight loss after oesophagectomy. Enteral nutrition via a feeding jejunostomy tube (FT) is commonly practised. This study aimed to assess the effect of severe weight loss postoperatively and enteral nutrition via an FT on long-term prognosis after oesophagectomy. METHODS: This study analysed 317 patients who underwent minimally invasive oesophagectomy at Kobe University Hospital and Hyogo Cancer Center from 2010 to 2015. The patients' body weight was evaluated at 3 months postoperatively. They were organised into the severe weight loss (n = 65) and moderate weight loss (n = 252) groups. Furthermore, they were categorised into the FT group (184 patients who had an FT placed during oesophagectomy) and no-FT group (133 patients without FT). Patients (119 per group) matched for the FT and no-FT groups were identified via propensity score matching. RESULTS: The 5-year overall survival (OS) rate in the severe weight loss group was significantly lower (p = 0.024). In the multivariate analysis, tumour invasion depth (pT3-4), preoperative therapy and severe weight loss had a worse OS (hazard ratio = 1.89; 95% confidence interval = 1.12-3.17, hazard ratio = 2.11; 95% confidence interval = 1.25-3.54, hazard ratio = 1.82; 95% confidence interval = 1.02-3.524, respectively). No significant differences in the number of severe weight loss patients and OS were found between the FT and no-FT groups. CONCLUSION: Severe weight loss is significantly associated with poor OS. In addition, enteral nutrition via an FT did not improve the severe weight loss and OS.Dec. 2020, BMC gastroenterology, 20(1) (1), 407 - 407, English, International magazineScientific journal
- PURPOSE: Minimally invasive esophagectomy (MIE) has been increasingly used, but many reports have stated that recurrent laryngeal nerve (RLN) palsy after MIE is a major complication associated with postoperative pneumonia. Prevention of RLN palsy clearly has been a challenging task. The study aim was to determine if a three-dimensional (3-D) stereoscopic vision system can reduce the RLN palsy rate after MIE. METHODS: This was a retrospective study of MIE (McKeown esophagectomy) using a 3-D or 2-D stereoscopic vision system to treat 358 patients in the prone position between April 2010 and March 2019. The patients who underwent 3-D MIE (3-D group) or 2-D MIE (2-D group) were matched by using propensity score matching. After matching, the perioperative outcomes were compared between the groups. RESULTS: After propensity score matching, 154 patients were analyzed (77 patients, 3-D group; 77 patients, 2-D group). There were no significant differences in the patients' baseline characteristics in the matched cohort. There were no significant differences in the rates of pneumonia (Clavien-Dindo (C-D) grade ≥ II, 3-D vs. 2-D, 11 (14%) vs. 12 (16%)), anastomotic leakage (C-D grade ≥ II, 10 (13%) vs. 18 (23%)) and mortality. The rates of left RLN palsy (C-D grade ≥ IIIa, 1 (1.3%) vs. 7 (9.1%), P = 0.029), right RLN palsy (C-D grade ≥ I, 2 (3%) vs. 8 (10%), P = 0.049), comprehensive complication index (CCI®) (8.5 vs. 14.3, P = 0.011), and postoperative hospital stay period (median: 25 vs. 30 days, P = 0.034) were significantly lower in the 3-D group than in the 2-D group, respectively. CONCLUSIONS: In MIE, the 3-D viewing system was one of the factors that reduced postoperative morbidities such as the rates of each RLN palsy and CCI®, leading to shorter postoperative hospital stay.Nov. 2020, Langenbeck's archives of surgery, 406(3) (3), 631 - 639, English, International magazineScientific journal
- Aim: The advantages of laparoscopic right hemicolectomy over open surgery for colon cancer in general clinical practice are debated, as evidenced by the continued use of open surgery in a significant proportion of patients worldwide. This study aimed to assess and compare the clinical outcome of laparoscopic and open right hemicolectomy for colon cancer using data from the Japanese National Clinical Database. Methods: A total of 72 299 patients who underwent laparoscopic (n = 46 084) and open (n = 26 215) right hemicolectomy for colon cancer between 2014 and 2018 were enrolled in this retrospective study. Short-term outcome was compared between groups using propensity score matching analysis. Results: The incidence of overall postoperative morbidity ≥ Clavien-Dindo classification grade 3 was significantly higher in the open surgery group than the laparoscopic group (4.7% vs 3.2%, P < .001). The incidence of most individual morbidities, including surgical site infection, anastomotic leakage, and ileus, was higher in the open surgery group. Short-term outcomes, including intraoperative blood loss, postoperative hospital stay, reoperation rate, 30-day mortality, and in-hospital mortality, were superior in the laparoscopic group, except for operative time. Subgroup analyses showed that the incidence of postoperative morbidity was lower in the laparoscopic group for all prespecified subgroups. Conclusion: Laparoscopic right hemicolectomy has an advantage over open surgery for colon cancer with respect to short-term outcome.Nov. 2020, Annals of gastroenterological surgery, 4(6) (6), 693 - 700, English, Domestic magazineScientific journal
- BACKGROUND: Omentoplasty is sometimes used to prevent perineal wound complications after abdominoperineal resection (APR) following neoadjuvant chemoradiotherapy (NACRT). However, recent studies have raised some controversy about its clinical benefit. PATIENTS AND METHODS: Outcomes for rectal cancer patients who received APR after NACRT were retrospectively compared between the groups with omentoplasty (n=28) and without omentoplasty (n=14). RESULTS: The operative time was significantly longer in the omentoplasty group (575 vs. 404 min, p<0.001). Laparoscopic surgery was performed more frequently in the omentoplasty group. Perineal wound problems including dehiscence and infection were significantly reduced in the omentoplasty group (46.4% vs. 78.6%, p<0.001). Univariate and multivariate analyses revealed that omentoplasty was the most important factor in reducing perineal wound complications (odds ratio=0.020, 95% confidence intervaI=0.001-0.393; p=0.001). CONCLUSION: Omentoplasty was useful in reducing perineal wound complications after APR following NACRT.Nov. 2020, Anticancer research, 40(11) (11), 6539 - 6543, English, International magazineScientific journal
- AIM: There is no consensus on the appropriate extent of oncological resection for tumours of the transverse colon. Concerns regarding tumour factors such as pattern of lymph node spread and technical factors such as anastomotic perfusion lead to a variety of procedures being performed. METHODS: A comprehensive search for published studies examining outcomes following segmental versus extended colectomy for transverse colon tumours was performed adhering to PRISMA (Preferred Reporting Items in Systematic Reviews and Meta-analyses) guidelines. Random effects methods were used to combine data. RESULTS: Seven comparative series examining outcomes in 3395 patients were identified. Segmental colectomy results in shorter operating times (mean difference 15.80 min, 95% CI -20.98 to -10.62, P < 0.001) and less ileus (OR 0.52, 95% CI 0.33-0.81, P = 0.004). There was no difference in length of hospital stay (mean difference 1.53 days, 95% CI -3.79 to 0.73, P = 0.18). Extended colectomy results in a lower rate of anastomotic leak (OR 0.62, 95% CI 0.40-0.97, P = 0.04). There are fewer nodes retrieved in segmental colectomy (mean difference 7.60 nodes, 95% CI -9.60 to -5.61, P < 0.001) but no difference in disease recurrence (OR 0.88, 95% CI 0.59-1.34, P = 0.56) or overall survival (OR 0.98, 95% CI 0.68-1.4, P = 0.9). CONCLUSIONS: Available data are limited due to a lack of randomized controlled trials. However, based on current evidence, segmental resection for transverse colon tumours is associated with less ileus but lower lymph node yields and higher anastomotic leak rates. Length of stay is similar. Oncological outcomes are equivalent.Oct. 2020, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 23(3) (3), 625 - 634, English, International magazine, Co-authored internationallyScientific journal
- BACKGROUND: Although transanal total mesorectal excision (ta-TME) is adopted for rectal cancer surgery by an increasing number of surgeons, it is still technically challenging. We have employed a lateral-first approach for ta-TME to overcome technical difficulties. However, its outcomes and advantage over conventional laparoscopic TME remain unclear. METHODS: Thirty-five consecutive patients who underwent ta-TME using a lateral-first approach (the ta-TME group) and 53 consecutive patients who underwent conventional laparoscopic TME (the lap-TME group) for low rectal cancer were included. Propensity score matching (PSM) was used to create balanced cohorts of ta-TME (n = 28) and lap-TME (n = 28). Their clinical outcomes were compared after PSM. RESULTS: The operative time and intraoperative blood loss were significantly lower in the ta-TME group than in the lap-TME group (P = 0.042 and P < 0.001, respectively). Postoperative complications ≥ Clavien-Dindo grade II were significantly less and postoperative hospital stay was significantly shorter in the ta-TME group (35.7% vs. 78.6%, P = 0.003, and 18 days vs. 32 days, P < 0.001, respectively). The distal margin was significantly larger in the ta-TME when excluding the abdominoperineal resection cases (20 mm vs. 10 mm, P = 0.032). The positive radial margin was observed in 2 of 28 patients (7.1%) in the ta-TME group. CONCLUSIONS: Ta-TME using a lateral-first approach is feasible and may offer several advantages over lap-TME in terms of short-term outcomes. It might be an alternative safe approach for ta-TME. To confirm the oncological superiority of this surgery, further study in a larger population and for a longer follow-up period is warranted.Sep. 2020, Surgical endoscopy, 35(2) (2), 971 - 978, English, International magazineScientific journal
- Esophageal cancer has a poor prognosis despite the fact that surgical techniques have been advanced and optimized, and systemic multimodality approaches have progressed recently. Adding chemotherapy, radiotherapy, and immunotherapy to the basic surgical approach have been shown to have therapeutic benefit for esophageal cancer. This review describes the latest development of chemoradiotherapy, chemotherapy, and immunotherapy, which have contributed to the reduction in esophageal cancer growth and improved the survival of patients. Chemoradiation is a treatment option for resectable esophageal cancer to preserve the esophagus for patients who cannot tolerate surgery. Moreover, a combination of chemoradiotherapy and salvage surgery could extend the survival of patients. The effects of a triplet chemotherapy regimen are currently being verified in some Phase III studies for unresectable advanced/recurrent esophageal cancer. In addition, with the great promise of immune checkpoint inhibitors, strategies that incorporate the use of immunotherapy may shift from the metastatic setting to the neoadjuvant/adjuvant setting as a result of clinical trials. More precise comprehension of the molecular biology of esophageal cancer is expected to further control disease progression using multimodality treatments in the future.Sep. 2020, Esophagus : official journal of the Japan Esophageal Society, 18(1) (1), 25 - 32, English, Domestic magazineScientific journal
- Oxford University Press (OUP), Sep. 2020, Diseases of the Esophagus
Summary The number of elderly patients with esophageal cancer has increased in recent years. The use of thoracoscopic esophagectomy has also increased, and its minimal invasiveness is believed to contribute to postoperative outcomes. However, the short- and long-term outcomes in elderly patients remain unclear. This study aimed to elucidate the safety and feasibility of minimally invasive esophagectomy in elderly patients. This retrospective study included 207 patients who underwent radical thoracoscopic esophagectomy for thoracic esophageal squamous cell carcinoma at Kobe University Hospital between 2005 and 2014. Patients were divided into non-elderly (<75 years) and elderly (≥75 years) groups. A propensity score matching analysis was performed for sex and clinical T and N stage, with a total of 29 matched pairs. General preoperative data, surgical procedures, intraoperative data, postoperative complications, in-hospital death, cancer-specific survival, and overall survival were compared between groups. The elderly group was characterized by lower preoperative serum albumin levels and higher American Society of Anesthesiologists grade. Intraoperative data and postoperative complications did not differ between the groups. The in-hospital death rate was 4% in the elderly group, which did not significantly differ from the non-elderly group. Cancer-specific survival was similar between the two groups. Although overall survival tended to be poor in the elderly group, it was not significantly worse than that of the non-elderly group. In conclusion, the short- and long-term outcomes of minimally invasive esophagectomy in elderly versus non-elderly patients were acceptable. Minimally invasive esophagectomy is a safe and feasible modality for elderly patients with appropriate indications.Scientific journal - Laparoscopic right hemicolectomy (LRH) is utilized worldwide as one of the standard surgical treatments for right-sided colon cancer. However, there have been issues concerning its applicability, techniques, and trend. The present study aimed to elucidate the current status and trend of LRH by reviewing literature focusing on important issues associated with this surgery. Based on previous studies, LRH most likely provides better short-term outcomes and similar oncological outcomes compared to open surgery. Despite the increasing use of robotic approach in this surgery, it seems to have always been associated with longer operative times and greater hospital cost with limited advantage. Intracorporeal anastomosis seems to improve short-term outcomes, such as quicker recovery of bowel function, compared to extracorporeal anastomosis. However, it does not contribute to shorter hospital stay. With regard to dissection technique, various approaches, and landmarks have been advocated to overcome the technical difficulty in LRH. This difficulty is likely to be caused by anatomical variation, especially in venous structures. The superiority of one approach or landmark over another is still argued about due to the lack of large-scale prospective studies. However, deep understanding both of anatomical variation and characteristics of each approach would be of extreme importance to minimize adverse effects and maximize patient benefit after LRH.Sep. 2020, Annals of gastroenterological surgery, 4(5) (5), 521 - 527, English, Domestic magazineScientific journal
- Retroperitoneal cellular angiofibroma (RCA) is very rare, and the optimal treatment for RCA has not been established. We report the case of RCA in a 58-year-old man who underwent curative laparoscopy-assisted resection. Preoperative computed tomography showed heterogeneous enhancement of the 7 cm diameter tumor in the pelvis. A smaller (2.3 cm) mass was also detected in the small intestine. The preoperative diagnosis was peritoneal metastasis of the gastrointestinal tumor of the small intestine. The pelvic tumor was laparoscopically mobilized from the rectum, the left ureter, and the left internal iliac vessels. The tumor was excised by detachment from the urinary bladder in laparotomy. The pathological diagnosis was RCA. The tumor had not recurred by the 1-year follow-up. The laparoscopic approach thus might be useful for resection of RCA.Jul. 2020, Asian journal of endoscopic surgery, 13(3) (3), 431 - 434, English, Domestic magazine[Refereed]
- INTRODUCTION: Three-dimensional (3D) laparoscopic vision can improve depth perception. However, it is a question whether 3D vision can improve motion in the depth direction. The aim of this study was to compare the impact of 3D vision on forceps motion in the depth and horizontal directions. METHODS: All data were obtained from our previous two studies, where, in total, 40 novices and 20 moderately experienced surgeons participated. A simple phantom task was performed in a training box. The participants were randomly assigned to two groups. Specifically, one group performed the task five times initially under a two-dimensional (2D) system, and the other group started under a 3D system. Both groups then performed the same task five times under the alternative system. Performances were recorded by an optical position tracker. We separately evaluated forceps motion in the x-, y-, and z-axis directions. RESULTS: Compared with the findings for 2D vision, the forceps path lengths were significantly decreased among novices and moderately experienced surgeons in almost all tasks under 3D vision. In a comparison of the path length ratio (3D/2D) in each direction, larger reduction was observed for the depth direction among novices, whereas no significant directional difference was noted among moderately experienced surgeons. CONCLUSIONS: For novices, 3D laparoscopic vision improves depth perception and may give shorter forceps movement in the depth direction even for simple tasks.Jul. 2020, Asian journal of endoscopic surgery, 13(3) (3), 265 - 271, English, Domestic magazine[Refereed]Scientific journal
- INTRODUCTION: Recent advances in the treatment for esophageal cancer have improved the prognosis after esophagectomy, but they have led to an increased incidence of gastric tube cancer. In most patients who underwent retrosternal reconstruction, median sternotomy is performed; it is associated with a risk of postoperative bleeding and osteomyelitis, and pain often negatively affects respiration. Here, we report the first case of thoracoscopic retrosternal gastric conduit resection in the supine position (TRGR-S). MATERIALS AND SURGICAL TECHNIQUE: A 75-year-old male patient was placed in the supine position. Four ports were placed in the left chest wall. The gastric tube was separated from the epicardium, sternum, and left brachiocephalic vein. Because of adhesions between the gastric tube and the right pleura, combined resection of the right pleura was performed. The dorsal side of the gastric tube was dissected before the ventral side, enabling the gastric tube to be suspended from the back of the sternum and, thus, making it easier to expose the surgical field. Next, pedicled jejunal reconstruction via the presternal route was performed. There were no postoperative complications. The pathological diagnosis was signet ring cell carcinoma (pT1b, pN0, M0, pStage I), indicating R0 resection. DISCUSSION: TRGR-S does not require sternotomy, reducing the risk of postoperative bleeding and osteomyelitis. In the presence of adhesions, TRGR-S is safe and provides a good surgical view. It is also reliable procedure for resection of retrosternal gastric tube cancer, and it is ergonomic for surgeons.Jul. 2020, Asian journal of endoscopic surgery, 13(3) (3), 461 - 464, English, Domestic magazine[Refereed]Scientific journal
- (一社)日本消化器外科学会, Jul. 2020, 日本消化器外科学会雑誌, 53(7) (7), 598 - 604, Japanese
- PURPOSE: The influence of anastomotic leakage on long-term survival in patients with rectal cancer is debatable. The aim of this study was to evaluate relationships between anastomotic leakage and long-term survival. METHODS: In this multicenter retrospective cohort study, 395 consecutive stage I to III rectal cancer patients underwent anterior resection between 2007 and 2012. Five-year overall survival, 5-year disease-free survival, and 5-year local recurrence-free survival were compared between patients with leakage (Leakage (+)) and patients without leakage (Leakage (-)). RESULTS: Of 395 patients, 50 (12.7%) had anastomotic leakage. Of these 50, 34 (68.0%) required urgent surgery and 16 (32.0%) could be managed by watchful waiting or with percutaneous drainage. The median follow-up period was 62.6 months. Five-year overall survival did not differ between the two groups (Leakage (+) 93.8% vs. Leakage (-) 89.0%, P = 0.121). Five-year disease-free survival also did not differ between the two groups (81.6% vs. 80.3%, P = 0.731), and neither did 5-year local recurrence-free survival (91.9% vs. 86.1%, P = 0.206). In a multivariable Cox regression model, BMI > 25, preoperative CA19-9 > 37, pathological T stage, pathological N stage, and circumferential resection margin (CRM) positive were independent predictors of disease-free survival. Moreover, pathological T stage, pathological N stage, and CRM positive were the only independent predictors of overall survival and local recurrence-free survival. Anastomotic leakage was not a risk factor for overall survival, disease-free survival, or local recurrence-free survival. CONCLUSION: Anastomotic leakage is not associated with a significant decrease in long-term survival in rectal cancer patients.Jul. 2020, International journal of colorectal disease, 35(7) (7), 1243 - 1253, English, International magazine[Refereed]Scientific journal
- PURPOSE: Skeletal muscle loss after gastrectomy can worsen patients' quality of life and prognosis. Laparoscopic gastrectomy is less invasive than open gastrectomy and has become commonly performed. However, the degree of skeletal muscle loss after laparoscopic procedures remains unclear. We herein report the degree and risk factors of psoas muscle loss after laparoscopic gastrectomy for gastric cancer. METHODS: The total psoas area (TPA) on computed tomography of 50 consecutive patients who underwent laparoscopic total gastrectomy (LTG) and 167 consecutive patients who underwent laparoscopic distal gastrectomy (LDG) for gastric cancer was retrospectively evaluated at one postoperative year. The TPA loss was compared between LDG and LTG and univariate and multivariate analyses were performed to identify the risk factors for TPA loss > 10%. RESULTS: The median TPA decrease rate was 5.9% in the LDG group and 15.6% in the LTG group. LTG and postoperative respiratory complications were independent factors associated with a severe TPA loss of > 10%. In the LTG group, no independent factors were identified in a multivariate analysis. In the LDG group, postoperative complications were identified as an independent risk factor for TPA loss > 10%. CONCLUSIONS: Laparoscopic gastrectomy leads to postoperative TPA loss, especially in patients who underwent LTG and had postoperative respiratory complications. Postoperative complications after LDG were also a risk factor for TPA loss.Jul. 2020, Surgery today, 50(7) (7), 693 - 702, English, Domestic magazine[Refereed]Scientific journal
- INTRODUCTION: Laparoscopic surgery has become popular for colorectal cancer treatment in recent years. However, its success rate even among high-risk patients remains debatable. The present study aims to compare the short- and long-term outcomes between laparoscopic and open surgeries in the American Society of Anesthesiologists (ASA) classes 3 and 4 patients with colorectal cancer. METHODS: This was a single-center, retrospective, cohort study performed at a university hospital, with 78 patients suffering from colorectal cancer who underwent surgery in ASA classes 3 and 4 as respondents. Patient and tumor characteristics, operative outcomes, and prognoses were factors compared between the open and laparoscopic groups. RESULTS: Compared with the open group, laparoscopic group had longer operation time (median 287.5 vs 204.5 minutes, P = .001), less operative blood loss (median 40 vs 240 mL, P = .020), and fewer postoperative complications (24% vs 55%, P = .011). In addition, operative approach (open vs laparoscopic) served as an independent factor for the occurrence of postoperative complications [HR = 3.963 (1.344-12.269), P = .013]. In terms of overall survival and recurrence-free survival (P = .171 and .087, respectively), no significant difference was found between the two groups. CONCLUSION: Laparoscopic surgery is thus associated with more favorable short-time outcomes and could be adopted as treatment even for colorectal cancer ASA class 3 and 4 patients.Jul. 2020, Asian journal of endoscopic surgery, 13(3) (3), 336 - 342, English, Domestic magazine[Refereed]Scientific journal
- PURPOSE: This study was conducted to determine whether establishing the proximal resection line using India ink tattooing can ensure safe resection margins during totally laparoscopic distal gastrectomy. METHODS: This retrospective study included 81 patients who underwent totally laparoscopic distal gastrectomy for gastric cancer on the lower two-thirds of the stomach. The proximal resection margins were analyzed with respect to the macroscopic type and clinical T stage, and the intraoperative appearance of the stain on the serosa was classified by reviewing surgical videos. RESULTS: R0 resection was performed in all patients. The rates of the intended margins were 89.2% in patients without a frozen section diagnosis and 84.2% in patients with differentiated type lesions who underwent a frozen section diagnosis; however, most patients with undifferentiated advanced lesions failed to achieve the intended resection margins. Intraoperative appearance revealed that 85.2% of patients had localized type stains, whereas 11.1% had widespread-type stains. CONCLUSIONS: Our procedure to determine the proximal resection line in totally laparoscopic distal gastrectomy is oncologically safe. However, careful observation of the resected specimen and a frozen section analysis should be performed for undifferentiated advanced lesions.Jun. 2020, Surgery today, 51(1) (1), 111 - 117, English, Domestic magazine[Refereed]Scientific journal
- Jun. 2020, Diseases of the colon and rectum, 63(6) (6), 859 - 859, English, International magazine[Refereed]Scientific journal
- BACKGROUND: We report a rare case of gastrointestinal stromal tumors (GISTs) in Carney's triad, successfully treated using laparoscopic gastrectomy with lymph node dissection after chemotherapy. CASE PRESENTATION: A 21-year-old woman presented to our hospital for treatment of recurrent GISTs. The patient had been admitted for treatment 11 years prior, with black stools being the chief presenting complaint at that time. On examination at that time, multiple submucosal tumors in the pyloric antrum and multiple pulmonary tumors had been observed. She underwent open partial gastrectomy, and the diagnosis of GISTs was confirmed. She was administered tyrosine kinase inhibitors to treat lung metastases from 2 months after surgery. Due to the increasing size of the lung tumors, a right upper lobectomy was performed 9 years after the index gastric surgery. Histopathological examination of the lung specimen, in combination with re-examination of the gastric specimens, was indicative of incomplete-type Carney's triad. Eleven years after the index gastric surgery, multiple GISTs were observed in her entire stomach. Tumor biopsy revealed a succinate dehydrogenase deficiency, confirming the diagnosis of recurrent GISTs. For treatment, the patient underwent laparoscopic completion gastrectomy, with D1 plus lymph node dissection. CONCLUSION: This is a first case report of completion gastrectomy performed laparoscopically for the treatment of GISTs associated with incomplete-type Carney's triad. The recurrent GISTs developed over a protracted period of 11 years from the index gastric surgery to tumor recurrence.May 2020, Surgical case reports, 6(1) (1), 112 - 112, English, International magazine[Refereed]Scientific journal
- BACKGROUND: The common use of laparoscopic intervention produces impressive amounts of video data that are difficult to review for surgeons wishing to evaluate and improve their skills. Therefore, a need exists for the development of computer-based analysis of laparoscopic video to accelerate surgical training and assessment. We developed a surgical instrument detection system for video recordings of laparoscopic gastrectomy procedures. This system, the use of which might increase the efficiency of the video reviewing process, is based on the open source neural network platform, YOLOv3. STUDY DESIGN: A total of 10,716 images extracted from 52 laparoscopic gastrectomy videos were included in the training and validation data sets. We performed 200,000 iterations of training. Video recordings of 10 laparoscopic gastrectomies, independent of the training and validation data set, were analyzed by our system, and heat maps visualizing trends of surgical instrument usage were drawn. Three skilled surgeons evaluated whether each heat map represented the features of the corresponding operation. RESULTS: After training, the testing data set precision and sensitivity (recall) was 0.87 and 0.83, respectively. The heat maps perfectly represented the devices used during each operation. Without reviewing the video recordings, the surgeons accurately recognized the type of anastomosis, time taken to initiate duodenal and gastric dissection, and whether any irregular procedure was performed, from the heat maps (correct answer rates ≥ 90%). CONCLUSIONS: A new automated system to detect manipulation of surgical instruments in video recordings of laparoscopic gastrectomies based on the open source neural network platform, YOLOv3, was developed and validated successfully.May 2020, Journal of the American College of Surgeons, 230(5) (5), 725 - 732, English, International magazine[Refereed]Scientific journal
- In the original article, there are errors in Fig. 1. Following is the corrected figure.Apr. 2020, Annals of surgical oncology, English, International magazine[Refereed]
- OBJECTIVE: Laparoscopic endoscopic cooperative surgery for duodenal tumors (D-LECS) has been developed to prevent duodenal leakage by reinforcing the endoscopic submucosal dissection site. However, there has been no prospective trial showing the feasibility of D-LECS. Herein, we conducted a single-arm confirmatory trial to evaluate the safety of D-LECS for non-ampullary superficial duodenal neoplasms. METHODS: This prospective single-center single-arm confirmatory trial analyzed patients with non-ampullary superficial duodenal neoplasms who underwent D-LECS. The primary endpoint was the incidence of any postoperative leakage occurring on the duodenal wall within 1 month postoperatively. The planned sample size was 20 patients, considering a threshold of 28% and one-sided alpha value of 5%. RESULTS: Between January 2015 and September 2018, 20 eligible patients were enrolled. Sixteen tumors were located in the second portion, three in the first portion, and one in the third portion of the duodenal region. The median operative time was 225 (134-361) min and the median blood loss was 0 (0-150) mL. Curative resection (R0) with negative margins was achieved in 19 cases. One case of postoperative leakage and one case of bleeding of grade 2 according to the Clavien-Dindo classification were observed in this series. The median duration of postoperative hospital stay was 9 (5-12) days. No local recurrence was observed in any patient during the median follow-up of 15.0 (12.0-38.0) months. CONCLUSIONS: This trial confirmed the safety and feasibility of D-LECS for non-ampullary superficial duodenal neoplasms with respect to the low incidence of postoperative duodenal leakage.Apr. 2020, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 33(3) (3), 373 - 380, English, International magazine[Refereed]Scientific journal
- BACKGROUND/AIM: To investigate the outcomes of laparoscopic surgery in colorectal cancer patients with dialysis. PATIENTS AND METHODS: Fourteen dialysis (dialysis group) and 567 non-dialysis (non-dialysis group) patients who underwent laparoscopic and open surgery for colorectal cancer between April 2008 and December 2015 were included. Short-term and long-term outcomes were compared between the groups. A 1:2 propensity score matching was performed to compare long-term outcomes. RESULTS: All the dialysis patients underwent laparoscopic surgery. There were no significant differences in operative outcomes and postoperative short-term outcomes between the two groups. In the whole cohort, overall survival of dialysis patients was shorter than that in the non-dialysis ones (p=0.020), while disease-free survival did not differ between the two groups. After matching, there was no significant difference between the groups in overall or disease-free survival. CONCLUSION: Laparoscopic colorectal cancer surgery for dialysis patients seems safe and feasible and associates with comparable short-term outcome and recurrence rate to non-dialysis patients.Apr. 2020, Anticancer research, 40(4) (4), 2165 - 2170, English, International magazine[Refereed]Scientific journal
- BACKGROUND: Oral health is associated with various diseases, including cancer. Tooth loss is a simple and objective index of oral health. OBJECTIVE: The purpose of this study was to investigate the association between preoperative tooth loss and esophageal cancer prognosis after esophagectomy. METHODS: This study included 191 patients who underwent esophagectomy for esophageal cancer after perioperative dental evaluation and oral care at Kobe University Hospital from April 2011 to March 2016. Patients were divided into two groups: Group A (tooth loss < 7) and Group B (tooth loss ≥ 7). Three-year overall survival (OS) and multivariate analysis were performed, along with subgroup analysis for elderly patients (age ≥ 65 years). RESULTS: The 3-year OS rate was 68.1% in Group A (104 patients) and 49.2% in Group B (87 patients). Group A had significantly higher OS than Group B (p = 0.002), and there were no significant differences in sex and clinical T or N stage between the two groups. However, the mean age of Group A was younger than that of Group B (64.2 vs. 68.5 years; p = 0.0002). Among elderly patients, the 3-year OS rate was 68.2% in Group A (55 patients) and 45.1% in Group B (65 patients) [p = 0.003]. Multivariate analysis that included age demonstrated that tooth loss is an independent prognostic factor (hazard ratio 1.87, 95% confidence interval 1.22-2.87), in addition to clinical T stage and preoperative serum albumin. CONCLUSION: Tooth loss is an independent prognostic factor for esophageal cancer after esophagectomy.Mar. 2020, Annals of surgical oncology, 27(3) (3), 683 - 690, English, International magazine[Refereed]Scientific journal
- BACKGROUND: Laparoscopic lateral pelvic lymph node dissection (LLND) has been reported to be feasible; however, studies comparing the outcomes of laparoscopic LLND with that of open LLND following preoperative chemoradiotherapy (CRT) are limited. METHODS: Between November 2005 and October 2017, 38 patients with locally advanced rectal cancer underwent total mesorectal excision and LLND following preoperative CRT at Kobe University Hospital. The data of the patients who underwent open LLND (OP group, n = 19) and laparoscopic LLND (LAP group, n = 19) were retrospectively collected and compared. RESULTS: The operative time was significantly longer in the LAP group compared with that in the OP group. However, the volume of blood loss was significantly higher, and transfusion was more frequently performed in the OP group than in the LAP group. The number of LLNs harvested in the LAP group was significantly higher than that in the OP group. The prevalence of perineal wound infection and bowel obstruction was significantly higher in the OP group than in the LAP group. However, no significant differences were observed between the groups in terms of 5-year overall survival, relapse-free survival, and local recurrence-free survival. CONCLUSIONS: Laparoscopic LLND is feasible and safe for patients with rectal cancer who were treated with preoperative CRT. Compared with open LLND, laparoscopic LLND might have several advantages such as higher yields of dissected LLNs and lower incidences of perineal wound infection and bowel obstruction.Mar. 2020, Surgical endoscopy, 34(3) (3), 1425 - 1431, English, International magazine[Refereed]Scientific journal
- 兵庫県外科医会, Mar. 2020, 兵庫県外科医会会誌, 54, 5 - 8, Japanese
- BACKGROUND: During the past decade, minimally invasive esophagectomy (MIE) for esophageal cancer has been adopted worldwide with expectations of lower invasiveness. However, the rate of postoperative pneumonia, which is an independent risk factor for oncological prognosis in esophageal cancer, remains high. The aim of this retrospective follow-up study is to clarify whether there is a strong correlation between recurrent laryngeal nerve (RLN) palsy and postoperative pneumonia in MIE. METHODS: This retrospective follow-up study included 209 patients with esophageal cancer who underwent thoracoscopic esophagectomy in the prone position (TEP) at Kobe University between 2011 and 2018. Inclusion criteria included age 18-85 years; cT1-3, cN0-3 disease; upper mediastinal lymphadenectomy; and ability to undergo simultaneous esophagectomy and reconstruction of the gastric conduit or pedicled jejunum. Univariate and multivariate logistic regression were conducted to identify independent risk factors for pneumonia. RESULTS: Among 209 TEPs, pneumonia of Clavien-Dindo classification grade > II occurred in 44 patients (21%). In the pneumonia positive and negative groups, there were significant differences in age (67.9 ± 7.5 vs. 64.9 ± 8.6 years), 3-field lymph node dissection [27 (61%) vs. 67 (41%)], transfusion [20 (45%) vs. 41 (25%)], left RLN palsy [19 (43%) vs. 18 (11%)], and any RLN palsy [20 (45%) vs. 18 (11%)]. In multivariate analysis, any RLN palsy was associated with a higher incidence of pneumonia [odds ratio (OR), 6.210; 95% confidence interval (CI), 2.728-14.480; P < 0.0001]. In addition, age was associated with a higher incidence of pneumonia (OR, 1.049; 95% CI, 1.001-1.103; P = 0.046). Changes in the rate of any RLN palsy over time were quite similar to changes in the incidence of pneumonia. CONCLUSION: There is a strong correlation between RLN palsy and pneumonia in MIE for esophageal cancer. Prevention of RLN palsy may reduce the incidence of pneumonia, leading to better oncological prognosis.Feb. 2020, Surgical endoscopy, 35(2) (2), 837 - 844, English, International magazine[Refereed]Scientific journal
- Esophagectomy for esophageal cancer is a highly invasive procedure, and a feeding jejunostomy tube (FJT) is routinely placed to ensure adequate enteral nutrition. However, the effect of perioperative short-term FJT placement remains controversial, and the aim of this study was to assess risks and benefits of routine FJT placement during esophagectomy and to determine parameters that can identify patients needing long-term FJT. This retrospective study included 393 patients who had undergone esophagectomy with gastric tube reconstruction via the posterior mediastinal route at the Kobe University Hospital and the Hyogo Cancer Center between April 2010 and December 2017. Propensity score matching was used to identify matched patients (139 per group) in the FJT and no-FJT groups. The incidence of postoperative complications and weight loss (3 months post-procedure) was compared in the matched cohort and significant risk factors predicting the need for long-term FJT placement in the whole cohort were identified. In the matched cohort, while weight loss was not different between the FJT and no-FJT groups (11% vs. 10%), the incidence of small bowel obstruction in the FJT group (11.5%) was significantly higher than that in the no-FJT group (0%). Multivariate analysis revealed that age (≥75 years), preoperative therapy, anastomosis leakage, and pulmonary complications were independent risk factors for long-term FJT placement. Routine placement of an FJT during esophagectomy increases small bowel obstruction and does not result in better nutritional status, suggesting that selective long-term FJT placement in high-risk patients should be considered.Jan. 2020, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 33(1) (1), English, International magazine[Refereed]Scientific journal
- Objectives: Dissection of the No. 11p lymph nodes is technically challenging because of variations in anatomical landmarks. This study aimed to determine the accuracy and efficacy of predicting the dorsal landmark of No. 11p lymph node using three-dimensional computed tomography simulation. Methods: Laparoscopic gastrectomy with No. 11p lymph node dissection with preoperative simulation using three-dimensional computed tomography was performed in 24 patients at our institution from October 2016 to May 2018. Initially, preoperative three-dimensional computed tomography findings with operative videos in these 24 patients were compared. The dorsal landmark was defined as an anatomical structure behind the splenic artery on preoperative three-dimensional computed tomography and operative videos. The dorsal landmark of No. 11p lymph node was divided into four types: (1) splenic vein type, (2) splenic vein and pancreas type, (3) pancreas type, and (4) unclear type. Then, to investigate the efficacy of three-dimensional computed tomography, we compared the clinical and pathological features and surgical outcomes of nine patients who underwent preoperative three-dimensional computed tomography simulation (three-dimensional computed tomography group) and 23 patients who did not undergo three-dimensional computed tomography simulation from August 2014 to September 2016 (non-three-dimensional computed tomography group). All procedures were performed by one surgeon certified by the Endoscopic Surgical Skill Qualification System in Japan. Results: The concordance rate between three-dimensional computed tomography and operative videos of the dorsal landmark using three-dimensional computed tomography was 79% (19/24). The operative time of No. 11p lymph node dissection was significantly shorter in the three-dimensional computed tomography group than in the non-three-dimensional computed tomography group (7.7 versus 15.8 min, P = 0.044). Conclusion: The accuracy of predicting the dorsal landmark of No. 11p lymph node using three-dimensional computed tomography was extremely high. Preoperative simulation with three-dimensional computed tomography was useful in shortening the operative time of No. 11p lymph node dissection.2020, SAGE open medicine, 8, 2050312120936918 - 2050312120936918, English, International magazine[Refereed]Scientific journal
- BACKGROUND: Esophagectomy with extended lymphadenectomy remains the mainstay of treatment for localized esophageal cancer. Currently, transthoracic and abdominal esophagectomy with cervical anastomosis (McKeown esophagectomy) is a frequently used technique in Japan. However, cervical anastomosis is still an invasive procedure with a high incidence of anastomotic leakage. The use of a drainage tube to treat anastomotic leakage is effective, but the routine placement of a closed suction drain around the anastomosis at the end of the operation remains controversial. The objective of this study is to evaluate the postoperative anastomotic leakage rate, duration to oral intake, hospital stay, and analgesic use with nonplacement of a cervical drainage tube as an alternative to placement of a cervical drainage tube. METHODS: This is an investigator-initiated, investigator-driven, open-label, randomized controlled parallel-group, noninferiority trial. All adult patients (aged ≥20 and ≤85 years) with histologically proven, surgically resectable (cT1-3 N0-3 M0) squamous cell carcinoma, adenosquamous cell carcinoma, or basaloid squamous cell carcinoma of the intrathoracic esophagus, and European Clinical Oncology Group performance status 0, 1, or 2 are assessed for eligibility. Patients (n = 110) with resectable esophageal cancer who provide informed consent in the outpatient clinic are randomized to either nonplacement of a cervical drainage tube (n = 55) or placement of a cervical drainage tube (n = 55). The primary outcome is the percentage of Clavien-Dindo grade 2 or higher anastomotic leakage. DISCUSSION: This is the first randomized controlled trial comparing nonplacement versus placement of a cervical drainage tube during McKeown esophagectomy with regards to the usefulness of a drain for anastomotic leakage. If our hypothesis is correct, nonplacement of a cervical drainage tube will be recommended because it is associated with a similar anastomotic leakage rate but less pain than placement of a cervical drainage tube. TRIAL REGISTRATION: UMIN-CTR, 000031244. Registered on 1 May 2018.Dec. 2019, Trials, 20(1) (1), 758 - 758, English, International magazine[Refereed]Scientific journal
- AIM: Total lymphocyte count in preoperative peripheral blood is associated with prognosis in various cancers. The predictive value of preoperative total lymphocyte count for survival was assessed in older gastric cancer patients after gastrectomy. METHODS: A total of 200 gastric cancer patients aged ≥75 years who underwent curative resection from 2000 to 2014 were included in this retrospective study. The cut-off value of total lymphocyte count in preoperative peripheral blood was determined using receiver operating characteristic curve analysis, and the association with prognosis was examined. RESULTS: The cut-off value of total lymphocyte count was 1462/μL, and 94 patients were classified as low total lymphocyte count patients and 106 patients were classified as high total lymphocyte count patients. In univariate analysis, American Society of Anesthesiologists score ≥3, Charlson Comorbidity Index ≥3, total lymphocyte count <1462/μL, stage III, open approach, total gastrectomy, splenectomy and infectious complication were significantly associated with overall survival. In multivariate analysis, total lymphocyte count <1462/μL (P = 0.003), American Society of Anesthesiologists score ≥3 (P = 0.01) and stage III (P = 0.017) were independent prognostic factors. Low total lymphocyte count significantly reduced overall survival in stage I (P = 0.037) and II (P = 0.009) patients, but not stage III patients (P = 0.29). CONCLUSION: Total lymphocyte count in preoperative peripheral blood can predict postoperative survival of older patients with relatively early-stage gastric cancer. Geriatr Gerontol Int 2019; 19: 1215-1219.Dec. 2019, Geriatrics & gerontology international, 19(12) (12), 1215 - 1219, English, Domestic magazine[Refereed]Scientific journal
- Dec. 2019, 癌と化学療法, 46(13) (13), 2327 - 2329, Japanese虫垂腺癌術後に吻合部再発と診断された神経内分泌癌の1例(原著論文)[Refereed]Scientific journal
- PURPOSE: Esophagectomy with extended lymphadenectomy remains the mainstay of treatment for localized esophageal squamous cell carcinoma (ESCC). Thoracic duct (TD) resection has been recommended as part of extended lymphadenectomy, although its merits are unclear. The aim of this two-institutional, matched-cohort study is to clarify whether TD resection improves prognosis in esophagectomy for ESCC. PATIENTS AND METHODS: In this two-institutional, matched-cohort study of 399 patients with ESCC who underwent McKeown esophagectomy between 2010 and 2014, the primary outcomes were overall survival (OS), disease-free survival (DFS), and cause-specific survival (CSS). Secondary outcomes were perioperative results and recurrence patterns. RESULTS: Based on a propensity score, 122 TD-resected or 122 TD-preserved patients in all stages were selected (median follow-up 4.5 years). The 5-year OS, DFS, and CSS rates in the TD-resected versus TD-preserved groups were 49% versus 60%, 53% versus 57%, and 58% versus 70%, respectively, without any significant differences. Operative time for the thoracic procedure was significantly longer and the number of retrieved mediastinal nodes was significantly higher in the TD-resected group (P = 0.009 and 0.005, respectively). The rates of chylothorax and left recurrent laryngeal nerve (RLN) palsy were significantly higher in the TD-resected group (P = 0.041 and 0.018, respectively). There were no significant differences in rates of local or distant metastases between the two groups. CONCLUSIONS: TD resection does not contribute to improve OS, DFS, or CSS in ESCC but increases incidence of chylothorax and left RLN palsy. Prophylactic TD resection should be avoided in esophagectomy for ESCC.Nov. 2019, Annals of surgical oncology, 26(12) (12), 4053 - 4061, English, International magazine[Refereed]Scientific journal
- BACKGROUND: Several studies have suggested that thoracoscopic esophagectomy (TE) in the prone position (TEP) may be more feasible than TE in the lateral position (TEL); however, few studies have compared long-term survival between the two procedures. We evaluated whether TEP is oncologically equivalent to TEL. METHODS: Surgical outcomes of TEs performed from January 2006 to December 2013 at our hospital were retrospectively analyzed. Propensity score matching was used to control for confounding factors. RESULTS: TE was performed in 200 patients diagnosed with esophageal squamous cell carcinoma; 78 patients were matched in two procedures. The mean thoracic operative time in TEL was shorter than in TEP (228.9 min vs. 299.1 min; p < 0.001); however, the mean thoracic blood loss in TEL was higher than in TEP (186.9 ml vs. 76.5 ml; p < 0.001). The mean number of thoracic lymph nodes harvested in TEL was lower than in TEP (23.5 vs. 26.9; p < 0.05), and the pulmonary complication rate in TEL was higher than in TEP (30.8% vs. 15.4%; p < 0.05). The 5-year overall survival rates in pathological stage I (81.2% vs. 81.6%; p = 0.82), stage II (65.3% vs. 80.9%; p = 0.21), stage III (26.7% vs. 24.2%; p = 0.86) and all stages (63.6% vs. 62.3%; p = 0.88), and the 5-year progression-free survival rates in pathological stage I (78.0% vs. 81.8%; p = 0.54), stage II (53.5% vs. 77.6%; p = 0.13), stage III (10.5% vs. 12.8%; p = 0.81) and all stages (53.6% vs. 57.9%; p = 0.50) were not significantly different between the two procedures. CONCLUSION: TEP and TEL provide equal oncological efficiency.Oct. 2019, Annals of surgical oncology, 26(11) (11), 3736 - 3744, English, International magazine[Refereed]Scientific journal
- BACKGROUND/AIM: To clarify the usefulness of intraoperative colonoscopy (CS) for preventing postoperative anastomotic leakage and bleeding in rectal cancer surgery. PATIENTS AND METHODS: The data of rectal cancer patients who underwent circular-stapled anastomosis from January 2008 to December 2016 were compared between 162 patients who received intraoperative CS (the CS group) and 23 patients who did not receive intraoperative CS (the non-CS group). RESULTS: Anastomotic leakage rate in the CS group (8.6%) was similar to that in the non-CS group (4.3%) (p=0.70). Postoperative anastomotic bleeding rate was also similar between the CS and non-CS groups (2.4% vs. 0%, p=0.50). Although a positive air leak test was observed in two patients in the CS group, no postoperative leakage developed by adding intraoperative treatment. CONCLUSION: Although intraoperative CS did not significantly reduce the incidence of postoperative anastomotic leakage or bleeding, it can be useful for certain cases.Oct. 2019, Anticancer research, 39(10) (10), 5761 - 5765, English, International magazine[Refereed]Scientific journal
- BACKGROUND/AIM: To investigate the impact of inguinal lymph node dissection (ILND) following neoadjuvant chemoradiotherapy (NACRT) for rectal cancer patients with ILN metastasis. PATIENTS AND METHODS: Forty-three patients with rectal cancer underwent NACRT followed by curative surgery between January 2005 and December 2016. Seven patients underwent ILND after NACRT for clinically-positive ILN metastasis (ILND (+) group), while the remaining 36 did not receive ILND for clinically negative ILN metastasis (ILND (-) group). Their outcomes were retrospectively analyzed. RESULTS: Only one patient in the ILND (+) group had a local recurrence at six years after surgery. The 5-year recurrence-free survival was 100% and 65.4% in the ILND (+) and ILND (-) groups, respectively (p=0.09), and the 5-year overall survival was 100% and 83.2%, respectively (p=0.32). CONCLUSION: ILND following NACRT seems effective for rectal cancer patients with ILN metastasis.Oct. 2019, Anticancer research, 39(10) (10), 5767 - 5772, English, International magazine[Refereed]Scientific journal
- INTRODUCTION: Anatomical evaluation of the splenic flexure vein is essential for complete mesocolic excision with central vascular ligation when treating patients with splenic flexure cancer. Although there have been several studies relating to the arterial branches of the splenic flexure, very limited data are available regarding the variation in venous anatomy in this region. METHODS: Sixty-six patients with colorectal cancer who underwent preoperative 3-D CT between April 2016 and April 2017 were included in this retrospective study. The pattern of the venous drainage of the splenic flexure and its association with the inferior border of the pancreas were evaluated. RESULTS: The inferior mesenteric vein flowed into the splenic vein in 32 patients (48.5%), into the superior mesenteric vein in 27 patients (40.9%), and into the confluence of splenic vein and superior mesenteric vein in 7 patients (10.6%). The splenic flexure vein joined the inferior mesenteric vein in 62 patients (93.9%), the splenic vein in 2 patients (3.0%), and the middle colic vein in 2 patients (3.0%). The splenic flexure vein flowed into the inferior mesenteric vein below the level of the inferior border of the pancreas in 58 patients (90.6%) and above it in 4 patients (6.3%). CONCLUSION: Preoperative evaluation of the venous pattern of the splenic flexure on 3-D CT is useful before complete mesocolic excision with central vascular ligation to avoid intraoperative bleeding during splenic flexure cancer surgery.Oct. 2019, Asian journal of endoscopic surgery, 12(4) (4), 412 - 416, English, Domestic magazine[Refereed]Scientific journal
- INTRODUCTION: Although a self-expanding metallic stent (SEMS) or a transnasal or transanal decompression tube is sometimes used as a bridge to surgery in patients with obstructive colorectal cancer, the optimal decompression procedure to achieve successful laparoscopic surgery remains unclear. METHODS: Forty-two patients with obstructive colorectal cancer who were preoperatively decompressed by using SEMS (the SEMS group, n = 20) or a decompression tube (the DT group, n = 22) between January 2010 and February 2017 were included in this retrospective study. RESULTS: In the SEMS group, 20 patients (100%) were able to eat and 17 patients (85%) were able to undergo total colonoscopy preoperatively, but no patients could do so in the DT group (P < 0.01 and P < 0.01, respectively). The serum albumin level increased in the time between admission and just before surgery in five patients in the SEMS groups (25%), whereas it decreased in all patients in the DT group (P = 0.037). Laparoscopic surgery was performed more frequently in the SEMS groups (19 patients, 95%) than in the DT group (13 patients, 59.1%) (P = 0.018). Primary anastomosis without stoma was also achieved more frequently in the SEMS groups (19 patients, 95%) than in the DT group (15 patients, 68.2%) (P = 0.047). Anastomotic leakage did not occur in the SEMS group, but it did occur in one patient in the DT group. The recurrence-free survival rate did not differ between the groups (median follow-up period: 21 months). CONCLUSION: In patients with obstructive colorectal cancer, SEMS appears to be more effective than a decompression tube as a preoperative treatment to achieve successful laparoscopic resection without stoma.Oct. 2019, Asian journal of endoscopic surgery, 12(4) (4), 401 - 407, English, Domestic magazine[Refereed]Scientific journal
- BACKGROUND: Esophagectomy with three-field lymph node dissection is common, but the effects of cervical lymph node dissection on overall survival in patients with thoracic esophageal cancer remain controversial. Recently, we performed thoracoscopic esophagectomy and superior mediastinum and paracervical esophageal lymph nodes could have been effectively dissected from the thoracic cavity. This study assessed the risks and benefits of prophylactic supraclavicular lymph node dissection in patients who underwent thoracoscopic esophagectomy. METHODS: This retrospective study included 294 patients who underwent thoracoscopic esophagectomy at Kobe University Hospital and Hyogo Cancer Center between April 2010 and December 2015. Patients in the two-field (paracervical esophageal lymph nodes were dissected from the thoracic cavity) and three-field lymph node dissection groups were matched using propensity score matching. We compared overall survival and the incidence of postoperative complications in the matched cohort and assessed the estimated efficacy of additional lymphadenectomy for supraclavicular lymph node recurrence in the entire cohort. RESULTS: In the matched cohort, overall survival was not significantly different between the two groups, but the incidence of recurrent laryngeal nerve palsy was significantly higher in the 3FL group than in the 2FL group. In the entire cohort, 162 patients underwent a two-field lymph node dissection; 11 experienced supraclavicular nodal recurrence. We performed additional supraclavicular lymph node dissection in three patients without systemic metastasis, all of whom are alive without any other recurrence. CONCLUSIONS: Prophylactic cervical lymph nodes dissection in thoracoscopic esophagectomy does not improve long-term survival but does increase the risk of postoperative complications.Sep. 2019, Annals of surgical oncology, 26(9) (9), 2899 - 2904, English, International magazine[Refereed]Scientific journal
- BACKGROUND: Laparoscopic complete mesocolic excision (CME) for hepatic or splenic flexural colon cancer is considered technically demanding. The double (hepatic and splenic) flexural colon cancers are rare, and the laparoscopic CME procedure for such disease is not standardized. METHODS: This video presents laparoscopic CME for double (hepatic and splenic) flexural colon cancers using a medial and cranial approach. RESULTS: The patient was a 60-year-old woman with the diagnosis of splenic flexure cancer (cT4N1M0) and hepatic flexure cancer (cT3N0M0). Laparoscopic subtotal colectomy was performed. First, the left colic artery was divided at its origin, and the inferior mesenteric vein also was divided at the same level. The descending mesocolon was widely separated from the retroperitoneal tissues using a medial approach. Then, lymph node dissection along the surgical trunk was performed using a cranial approach. Finally, the transverse mesocolon was divided at the inferior border of the pancreas, and CME was achieved. The specimen was extracted through a small incision at the umbilicus, and side-to-side ileo-sigmoid anastomosis was performed extracorporeally. CONCLUSIONS: The approach presented in the video might be useful for standardization of laparoscopic CME for double flexural colon cancers.Aug. 2019, Annals of surgical oncology, 26(8) (8), 2516 - 2516, English, International magazine[Refereed]Scientific journal
- BACKGROUND/AIM: The aim of this study was to investigate PD-L1 expression and its association with prognosis in esophageal squamous cell carcinoma (ESCC) before and after neoadjuvant chemotherapy (5-fluorouracil and cisplatin, NAC-FP). PATIENTS AND METHODS: Using a database of 69 ESCC patients, we analyzed PD-L1 expression on tumor cells (TCs) and immune cells (ICs), as well as the density of CD8+ tumor-infiltrating lymphocytes (TILs) in pretreatment biopsy specimens-versus-surgical specimens after resection. We determined the prognostic significance of these factors. RESULTS: The fraction of ESCC containing ICs expressing PD-L1 and having a high CD8+ TIL density was significantly increased after neoadjuvant treatment. However, PD-L1 expression on TCs or ICs, and CD8+ TIL density, was not significantly associated with patient survival in ESCC patients. CONCLUSION: NAC-FP induced PD-L1 expression on ICs and CD8+ TILs in ESCC patients. This finding suggests that PD-1/PD-L1 blockade could be combined with NAC-FP to treat ESCC patients.Aug. 2019, Anticancer research, 39(8) (8), 4539 - 4548, English, International magazine[Refereed]Scientific journal
- PURPOSE: The surgical indication of laparoscopic surgery for pT4 colon cancer remains to be established because only a few studies have investigated the short- and long-term outcomes of laparoscopic surgery for them to date. Therefore, we aimed to elucidate the validity of laparoscopic surgery for them. METHODS: We retrospectively analyzed 81 patients with pT4 colon cancer who underwent surgical resection with a curative intent at Kobe University Hospital from January 2007 to December 2015. The short- and long-term outcomes were compared between the propensity score-matched patients who underwent laparoscopic colectomy (LAP group, n = 25) and those who underwent open colectomy (OP group, n = 25). RESULTS: Intraoperative blood loss was significantly less in the LAP group than in the OP group (p = 0.029). Operative time, R0 resection rate, and morbidity did not significantly differ between the two groups. The 5-year overall survival (OS) and the 5-year recurrence-free survival (RFS) did not significantly differ between the propensity score-matched groups. Univariate and multivariate analyses of the entire cohort showed the surgical approach (LAP vs OP) selected was not a significant prognostic factor for OS or RFS. CONCLUSIONS: The short and the long-term outcomes were similar between the LAP and OP groups. Laparoscopic surgery might be a safe and feasible option for pT4 colon cancer patients.Jul. 2019, International journal of colorectal disease, 34(7) (7), 1259 - 1265, English, International magazine[Refereed]Scientific journal
- Mirror image is one of the most difficult situations that the assistant surgeon encounters in laparoscopic colorectal surgery. The aim of the present study was to investigate whether task performance with mirror images improves by changing the position of the monitor and the rotation angle of the camera. Twenty-four surgeons performed the task under different conditions: Coaxial image (C), Mirror image (M), Mirror image + Monitor on the left side of participants (M + Mon), Mirror image + Camera rotated 90 degrees to the right (M + Cam), and Mirror image + Monitor on the left side + Camera rotated to the right (M + Mon + Cam) in a training box. The outcome measure was the mean time for completing the task. The mean time for completing the task, in decreasing order, was M (111.4 ± 58.9 seconds) > M + Mon (70.5 ± 29.4 seconds) > M + Cam (47.1 ± 17.1 seconds) > M + Mon + Cam (33.4 ± 10.3 seconds) > C (20.5 ± 3.5 seconds). (multivariable analysis of variance (MANOVA), p = 7.9 × 10-7) Task performance with mirror images improved by changing the monitor positioning and camera rotation angle. This novel method is a simple way to overcome mirror image in laparoscopic colorectal surgery.Jun. 2019, Scientific reports, 9(1) (1), 8371 - 8371, English, International magazine[Refereed]Scientific journal
- BACKGROUND: To perform a safe and precise laparoscopic surgery for the splenic flexure cancer, it is important for surgeons to gain a preoperative understanding of the running of the feeding artery of the splenic flexure. We evaluated the blood supply to the splenic flexure by using preoperative three-dimensional computed tomography (3D-CT). METHOD: We retrospectively analyzed a total of 88 patients with colorectal cancer who underwent preoperative 3D-CT at our institutions between April 2016 and June 2017. RESULTS: The arterial blood supply to the splenic flexure was divided into four patterns as follows: type 1, the left branch of the middle colic artery (MCA) with common trunk and the left colic artery (LCA) (n = 48, 54.5%); type 2, the left branch of the MCA with independent origin and the LCA (n = 8, 9.1%); type3, the accessory-MCA (A-MCA) and the LCA (n = 27, 30.7%); and type4, the LCA alone (n = 5, 5.7%). The MCA had the common trunk of the right and left branches in the majority of cases (85.2%). The right and left branches of the MCA arose separately from the superior mesenteric artery (SMA) in 8 of 88 patients (9.1%). CONCLUSIONS: The arterial patterns of the splenic flexure were classified into four patterns by using preoperative 3D-CT. The A-MCA existed in 30% of the patients in this study. These information should be helpful to perform the optimal surgery for the splenic flexure cancer.Jun. 2019, International journal of colorectal disease, 34(6) (6), 1047 - 1051, English, International magazine[Refereed]Scientific journal
- PURPOSE: In esophageal squamous cell carcinoma (ESCC), lymph nodes (LNs) around the subcarina and main bronchi are thought to be highly involved. Therefore, complete dissection of these LNs with preservation of the pulmonary branches of the vagus nerves, which control important pulmonary functions, is recommended. The aim of this retrospective study was to investigate the feasibility of reliable method for lymphadenectomy around the subcarina and main bronchi, named the medial approach, during thoracoscopic esophagectomy in the prone position (TEP). METHODS: This was a case-matched control study of patients who underwent TEP for ESCC. The fundamental concept in this method is to first exfoliate the LNs around the subcarina and main bronchi from the pericardium. Developing the operative field contributes to visualizing and preserving the pulmonary branches of the right vagus nerve. Twenty-three patients who underwent the medial approach and 23 patients who underwent the conventional approach were selected by the use of propensity score matching to compare the operative outcomes. RESULTS: The medial approach significantly reduced operative time for procedure (16 ± 3 vs 30 ± 6 min, p < 0.0001) and operative blood loss (123 ± 108 vs 207 ± 162 ml, p = 0.046) comparing with conventional approach. The incidence of postoperative pneumonia was lower in the medial approach group (4%) than in the conventional approach group (15%) (p = 0.069). CONCLUSIONS: The medial approach for lymphadenectomy around the subcarina and both main bronchi during TEP is technically safe and feasible in shorting the operative time with possibility to reduce postoperative pneumonia.May 2019, Langenbeck's archives of surgery, 404(3) (3), 359 - 367, English, International magazine[Refereed]Scientific journal
- BACKGROUND: Single-incision laparoscopic surgery (SILS) has recently been used for the management of gastrointestinal stromal tumors (GIST). Here, the feasibility and effectiveness of SILS for GIST and indications for SILS according to tumor location were investigated. CASE PRESENTATION: From July 2009 to May to 2013, a total of 14 patients underwent SILS for GIST. In 14 patients, 5 patients had tumor near the esophagogastric junction, 4 patients on the lesser curvature, 2 patients on the anterior wall, 2 patients on the posterior wall, and 1 patient on the greater curvature. The surgery of one patient with lesser curvature tumor was converted to conventional laparoscopic surgery because of technical difficulties. Another patient required re-operation because of a posterior wall tumor causing gastric obstruction. There was no complication in patients with tumors on the anterior wall and greater curvature. CONCLUSIONS: Because SILS for GISTs located mainly on the anterior wall was feasible, SILS may be considered the most appropriate type of laparoscopic surgery for GISTs in this location. However, for GISTs on the posterior wall or with lesser curvature, which require more complex management, SILS is challenging and should be carefully adapted.Mar. 2019, Surgical case reports, 5(1) (1), 50 - 50, English, International magazine[Refereed]Scientific journal
- Esophagectomy with extended lymphadenectomy remains the mainstay of treatment for localized esophageal cancer. However, it is one of the most invasive procedures with high morbidity. To reduce invasiveness, minimally invasive esophagectomy (MIE), which includes thoracoscopic, laparoscopic, mediastinoscopic, and robotic surgery, is becoming popular worldwide. Thoracoscopic esophagectomy in the prone position is ergonomic for the surgeon and has better perioperative arterial oxygen pressure/fraction of inspired oxygen (P/F) ratio. Thoracoscopic esophagectomy in the left decubitus position is easy to introduce because it is similar to standard right posterolateral open esophagectomy (OE) in position. It has a relatively short operative time. Laparoscopic approach could potentially have a substantial effect on pneumonia prevention under the condition of thoracotomy. Mediastinoscopic surgery has the potential to reduce pulmonary complications because it can avoid a transthoracic procedure. In robotic surgery, in the future, less recurrent laryngeal nerve palsy will be expected as a result of polyarticular fine maneuvering without human tremors. In studies comparing MIE with OE, mediastinoscopic surgery and robotic surgery are usually not included; these studies show that MIE has a longer operative time and less blood loss than OE. MIE is particularly beneficial in reducing postoperative respiratory complications such as atelectasis, despite no dramatic decrease in pneumonia. Reoperation might occur more frequently with MIE. There is no significant difference in mortality rate between MIE and OE. It is important to recognize that the advantages of MIE, particularly "less invasiveness", can be of benefit at facilities with experienced medical personnel.Mar. 2019, Annals of gastroenterological surgery, 3(2) (2), 138 - 145, English, Domestic magazine[Refereed]Scientific journal
- AIM: To evaluate the clinical significance of lateral pelvic lymph node (LLN) size in predicting pathological metastasis and prognosis in rectal cancer treated with preoperative chemoradiotherapy (CRT) followed by surgery. PATIENTS AND METHODS: Fifty-two patients with rectal cancer who underwent curative surgery after preoperative CRT were included. Fifteen patients underwent total mesorectal excision (TME) alone, while 37 patients underwent TME with LLN dissection for clinical LLN metastasis. RESULTS: Pathological metastasis was identified in seven (2.6%) out of 270 resected LLNs in six (16.2%) out of 37 patients. The cut-off value of the short-axis diameter was 7.0 mm before and 6.0 mm after CRT. The 5-year recurrence-free survival rate was significantly higher in patients with LLNs <7.0 mm than in those with LLNs ≥7.0 mm (85.7% versus 56.8%, p=0.038). CONCLUSION: Short-axis diameter of LLNs of 7.0 mm seems to be an optimal cut-off value before CRT for predicting pathological metastasis and prognosis.Feb. 2019, Anticancer research, 39(2) (2), 993 - 998, English, International magazine[Refereed]Scientific journal
- Neoadjuvant chemoradiotherapy (nCRT) has been widely used as a multidisciplinary approach for stage II/III rectal cancer. However, its safety and efficacy are controversial because previous studies have shown conflicting outcomes. The present review aimed to elucidate the benefits and limitations of nCRT for patients with rectal cancer. Future perspectives of nCRT are also described. No recent randomized trials have been able to show a survival benefit, although many studies have demonstrated good local control with the use of fluoropyrimidine (e.g. 5-fluorouracil [FU] or capecitabine)-based nCRT. Addition of oxaliplatin (OX) to FU-based nCRT might improve overall survival by preventing distant metastasis, as shown in recent meta-analyses. However, control of adverse effects is an important concern with this treatment. New treatment strategies such as nonoperative management (watch and wait policy) and total neoadjuvant therapy (TNT) are promising, but the establishment of reliable diagnostic methods of metastasis is essential. Development of new biomarkers is also necessary to select patients who are more likely to benefit from nCRT.Jan. 2019, Annals of gastroenterological surgery, 3(1) (1), 24 - 33, English, Domestic magazine[Refereed]Scientific journal
- PURPOSE: The prognosis of esophageal cancer is dismal, and the 3-year overall survival of cStage III does not reach 50.0%. C-reactive protein (CRP) is a well-known protein that reflects the short- and long-term operative outcomes of esophageal cancer. However, since elevated CRP levels are often observed in cStage III esophageal cancer, whether or not CRP still reflects the prognosis is unclear. METHODS: Eighty-four patients who were diagnosed with cStage III esophageal cancer and underwent R0/1 operation from January 2007 to December 2014 were retrospectively evaluated. RESULTS: The mean age was 66.8 years, and the majority of patients were male. The median preoperative and postoperative CRP levels were 0.15 and 1.47 mg/dl, respectively. A majority of the patients underwent thoracoscopic surgery, and the median blood loss and operation duration were 456 ml and 11.6 h, respectively. Forty-six patients (54.8%) died during the observation period, and the 3-year overall survival was 52.4%. A multivariate analysis showed that the preoperative CRP level, postoperative albumin level, blood loss, and complications were independent prognostic factors. A multiple linear regression analysis showed that an elevated postoperative CRP level was affected by the operation duration and preoperative CRP levels. CONCLUSIONS: These findings suggest that the preoperative CRP level is a prognostic factor for cStage III esophageal cancer and that postoperative elevation in the CRP level is affected by the operation duration.Jan. 2019, Surgery today, 49(1) (1), 90 - 95, English, Domestic magazine[Refereed]Scientific journal
- Dec. 2018, Ann Thorac Surg, 106(6) (6), e309 - e311, EnglishMass-Forming Deep Pseudodiverticulosis of the Esophagus With 18F-Fluorodeoxyglucose Uptake[Refereed]Scientific journal
- Oct. 2018, Surg Endosc, 32(10) (10), 4228 - 4234, EnglishThe effect on surgical skills of expert surgeons using 3D/HD and 2D/4K resolution monitors in laparoscopic phantom tasks[Refereed]Scientific journal
- Oct. 2018, World J Surg, 42(10) (10), 3398 - 3404, EnglishOptimal Surgery for Mid-Transverse Colon Cancer: Laparoscopic Extended Right Hemicolectomy Versus Laparoscopic Transverse Colectomy[Refereed]Scientific journal
- Sep. 2018, Anticancer Res, 38(9) (9), 5289 - 5294, EnglishSignificance of Additional Gastrectomy Including Endoscopic Submucosal Dissection Scar for Gastric Cancer[Refereed]Scientific journal
- PURPOSE: Endoscopic submucosal dissection (ESD) is widely used to treat esophageal cancer, but some patients require additional treatment due to the possibility of lymph node metastasis. The aim of this study was to elucidate the clinical outcomes of these additional treatments. METHODS: The study included 59 patients who developed superficial esophageal squamous cell carcinoma after noncurative ESD treated between 2005 and 2016, of whom 28 underwent esophagectomy and 31 received chemoradiotherapy (CRT). RESULTS: The median follow-up periods were 45 months in the esophagectomy group and 41 months in the CRT group. The overall survival did not differ significantly between the groups (P = 0.46). However, there were no recurrences in the esophagectomy group, and the disease-specific survival rate was significantly higher in this group (P = 0.042). Among the patients at high risk for recurrence due to massive tumor invasion (≥ SM2) with lymphovascular invasion (esophagectomy group, six patients; CRT group, ten patients), none in the esophagectomy group had recurrence, whereas four in the CRT group died of esophageal cancer (P = 0.031). CONCLUSION: The overall survival did not differ significantly between the groups. However, compared with CRT, esophagectomy provided more favorable disease control for patients with massive tumor invasion (≥ SM2) with lymphovascular invasion.Aug. 2018, Surgery today, 48(8) (8), 783 - 789, English, Domestic magazine[Refereed]Scientific journal
- Aug. 2018, ANN GASTROENTEROL SURG, 2(6) (6), 400 - 405, EnglishRecent updates in perioperative chemotherapy and recurrence pattern of gastric cancer[Refereed]Scientific journal
- Springer Tokyo, Jun. 2018, Esophagus, 1 - 8, English[Refereed]Scientific journal
- Springer New York LLC, Apr. 2018, World Journal of Surgery, 42(4) (4), 1065 - 1072, English[Refereed]Scientific journal
- Apr. 2018, 癌と化学療法, 45(4号) (4号), 709 - 711, JapaneseTrastuzumab Capecitabine Cisplatin療法により治癒切除し得た胃癌腹膜転移の1例[Refereed]Scientific journal
- Springer Verlag, Mar. 2018, Langenbeck's Archives of Surgery, 403(2) (2), 221 - 234, English[Refereed]Scientific journal
- Mar. 2018, 癌と化学療法, 45(3) (3), 471 - 473, JapaneseS-1/CDDP療法後に手術を施行し長期予後を得ている胃癌腹膜播種の1例[Refereed]Scientific journal
- Springer New York LLC, Mar. 2018, Surgical Endoscopy and Other Interventional Techniques, 32(3) (3), 1202 - 1208, English[Refereed]Scientific journal
- Springer New York LLC, Feb. 2018, Surgical Endoscopy and Other Interventional Techniques, 32(2) (2), 582 - 588, English[Refereed]Scientific journal
- Feb. 2018, ANN GASTROENTEROL SURG, 2(2) (2), 129 - 136, EnglishRecent updates in the surgical treatment of colorectal cancer[Refereed]
- INTRODUCTION: Primary appendiceal cancer with fistula formation is extremely rare. We report a case of a patient with appendiceal cancer invading the ileum who underwent successful laparoscopic ileocecal resection. PRESENTATION OF CASE: A 76-year-old man who presented with fever and abdominal pain was diagnosed with acute appendicitis and received antibiotics at a local hospital. After a few days, he was referred to our hospital because of an abnormality found in the colonoscopy, which was an oozing ulcer in the terminal ileum. Laparoscopic ileocecal resection was performed with a preoperative diagnosis of ileal cancer. The tumor adhered to the right internal inguinal ring. We dissected the right spermatic cord involved in the tumor. The resected specimen revealed a fistula between the appendiceal orifice and ileac ulcer. Histopathological examination revealed a well differentiated tubular adenocarcinoma. We made the diagnosis of appendiceal cancer with an ileal fistula because the ileal ulcer was derived from the appendiceal site. DISCUSSION: Most cases of appendiceal cancer with a fistula undergo laparotomy, but in selected cases, laparoscopic resection should be considered a feasible, safe, and curative procedure. Our patient underwent laparoscopic ileocecal resection, whereby the tumor and other organs with invasion were resected successfully with a negative surgical margin. CONCLUSION: This is the first case report of appendiceal cancer with an ileal fistula successfully treated with laparoscopic resection. Laparoscopic ileocecal resection can be applied for appendiceal cancers with a fistula by experienced surgeons with careful consideration.2018, International journal of surgery case reports, 52, 120 - 124, English, International magazine[Refereed]Scientific journal
- Dec. 2017, ANNALS OF SURGICAL ONCOLOGY, 24(13) (13), 3934 - 3946, English[Refereed]Scientific journal
- Oxford University Press, Dec. 2017, Diseases of the Esophagus, 30(12) (12), 1 - 5, English[Refereed]Scientific journal
- Background and study aims Endoscopic submucosal dissection (ESD) for duodenal tumors results in a high delayed perforation rate due to the thinness of the duodenal wall. In most cases with perforation after duodenal ESD, additional surgery is needed due to severe peritonitis. A newly developed procedure, laparoscopic endoscopic cooperative surgery for duodenal tumors (D-LECS), may help to avoid perforation after ESD. In our institution, patients with superficial non-ampullary duodenal epithelial tumors (SNADET) smaller than 50 mm which could not have en-bloc resection by endoscopic mucosal resection were treated with D-LECS. After a laparoscopic exposure of anterior duodenal wall of second portion, ESD was performed. Laparoscopic suturing from the serosal side of ESD site was performed for reinforcement. There were neither postoperative leakage nor other complications. Therefore, D-LECS can be performed safely and prevent perforation after ESD for SNADET. D-LECS could be selected as a treatment for SNADET which can be cured by ESD.Nov. 2017, Endoscopy international open, 5(11) (11), E1153-E1158 - E1158, English, International magazine[Refereed]Scientific journal
- Nov. 2017, ANNALS OF SURGICAL ONCOLOGY, 24(12) (12), 3673 - 3673, English[Refereed]Scientific journal
- Nov. 2017, 日本外科学会雑誌, 118(6) (6), 639 - 645, Japanese【分子標的療法は外科治療をどう変えるか】 大腸癌[Refereed][Invited]
- Sep. 2017, ANNALS OF SURGICAL ONCOLOGY, 24(9) (9), 2727 - 2727, English[Refereed]Scientific journal
- Sep. 2017, ANN GASTROENTEROL SURG, 2(1) (1), 72 - 78, EnglishLong-term impact of postoperative pneumonia after curative gastrectomy for elderly gastric cancer patients[Refereed]Scientific journal
- Aug. 2017, ANTICANCER RESEARCH, 37(8) (8), 4195 - 4198, English[Refereed]Scientific journal
- Aug. 2017, ANNALS OF SURGICAL ONCOLOGY, 24(8) (8), 2302 - 2302, English[Refereed]Scientific journal
- Aug. 2017, 手術, 71(9) (9), 1335 - 1340, Japanese手術手技 3ステップ法による腹腔鏡下脾彎曲授動の定型化[Refereed]
- Jul. 2017, ANTICANCER RESEARCH, 37(7) (7), 3863 - 3869, English[Refereed]Scientific journal
- May 2017, LANGENBECKS ARCHIVES OF SURGERY, 402(3) (3), 493 - 500, English[Refereed]Scientific journal
- We have developed a new method to localize a tumor during totally laparoscopic gastrectomy that uses intraoperative laparoscopic ultrasonography combined with preoperative clipping and tattooing. One or 2 days before the surgery, endoscopic clipping was performed just proximal to the tumor, followed by tattooing with India ink at the clipping site. Examination by intraoperative laparoscopic ultrasonography was performed at the tattooed site to detect the clips. The resection line of the stomach was determined with use of the detected clips as a marker of the proximal margin of the tumor. This method was attempted in 14 patients who underwent totally laparoscopic gastrectomy, and the clips were successfully identified in all patients. The clips were visualized as several layers of a hyperechoic bar, which was termed a "ladder sign." The mean time from insertion of the laparoscopic probe to identification of the clips was 2 min. The ladder sign is an important finding in this method.May 2017, Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 20(3) (3), 548 - 552, English, Domestic magazine[Refereed]Scientific journal
- Apr. 2017, ANNALS OF SURGICAL ONCOLOGY, 24(4) (4), 1018 - 1018, English[Refereed]Scientific journal
- Mar. 2017, SURGERY TODAY, 47(3) (3), 313 - 319, English[Refereed]Scientific journal
- Mar. 2017, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 31(3) (3), 1496 - 1504, English[Refereed]Scientific journal
- Jan. 2017, WORLD JOURNAL OF CLINICAL CASES, 5(1) (1), 18 - 23, English[Refereed]Scientific journal
- Jan. 2017, INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 32(1) (1), 139 - 141, English[Refereed]Scientific journal
- Sep. 2016, LANGENBECKS ARCHIVES OF SURGERY, 401(6) (6), 797 - 804, English[Refereed]Scientific journal
- 2016, Cytometry research, 26(2) (2), 27 - 31, Japanese担癌状態における骨髄由来抑制細胞(Myeloid derived suppressor cells) の治療による変化[Refereed]
- 2016, Cytometry research, 26(2) (2), 21 - 25, JapaneseAlpha-galactosylceramide による iNKT 細胞活性化と肝傷害[Refereed]
- Jun. 2014, HEPATO-GASTROENTEROLOGY, 61(132) (132), 1028 - 1032, English[Refereed]Scientific journal
- Jul. 2012, HEPATO-GASTROENTEROLOGY, 59(117) (117), 1433 - 1436, English[Refereed]Scientific journal
- Nov. 2010, WORLD JOURNAL OF GASTROENTEROLOGY, 16(41) (41), 5247 - 5251, English[Refereed]Scientific journal
- 第96回日本胃癌学会総会, Japanese, 京都府立医科大学大学院医学研究科 消化器外科学, 京都市, Japan, Domestic conference十二指腸表在性腫瘍に対する腹腔鏡内視鏡合同手術における結腸間膜尾側からのアプローチの有用性の検討Public symposium
- 第96回日本胃癌学会総会, Japanese, 京都府立医科大学大学院医学研究科 消化器外科学, 京都市, Japan, Domestic conference高齢の胃癌患者に対する術前化学療法の安全性についての検討Oral presentation
- 第96回日本胃癌学会総会, Japanese, 京都府立医科大学大学院医学研究科 消化器外科学, 京都市, Japan, Domestic conference切除困難な胃GISTに対する術前イマチニブによる補助療法の有用性に関する検討Public symposium
- 第96回日本胃癌学会総会, English, 京都府立医科大学大学院医学研究科 消化器外科学, 京都市, Japan, Domestic conferenceThe significance of conversion surgery following chemotherapy for clinical stage IV gastric cancerOral presentation
- 第96回日本胃癌学会総会, Japanese, 京都府立医科大学大学院医学研究科 消化器外科学, 京都市, Japan, Domestic conference当院における進行胃癌に対するロボット支援下胃切除術の工夫Oral presentation
- 第96回日本胃癌学会総会, Japanese, 京都府立医科大学大学院医学研究科 消化器外科学, 京都市, Japan, Domestic conference食道胃接合部腺癌に対する腹腔鏡下経裂孔的再建における左横隔膜開放法の有用性Public symposium
- 第56回制癌剤適応研究会, Japanese, 藤田医科大学医学部消化器外科学講座 ばんたね病院外科, 下呂市, Japan, Domestic conference術前化学療法を施行した食道癌における腫瘍マーカーと生存転帰の検討Oral presentation
- 第56回制癌剤適応研究会, Japanese, 藤田医科大学医学部消化器外科学講座 ばんたね病院外科, 下呂市, Japan, Domestic conference切除不能進行胃癌に対する conversion surgery の周術期化学療法の重要性及び治療成績Public symposium
- 第56回制癌剤適応研究会, Japanese, 藤田医科大学医学部消化器外科学講座 ばんたね病院外科, 下呂市, Japan, Domestic conference大腸癌腫瘍免疫微小環境における CD4+T 細胞に与える肥満の影響Oral presentation
- 第56回制癌剤適応研究会, Japanese, 藤田医科大学医学部消化器外科学講座 ばんたね病院外科, 下呂市, Japan, Domestic conference鼠径リンパ節転移を伴う直腸・肛門管腺癌の術後成績;術前治療と選択的鼠径リンパ節郭清・直腸間膜全切除による治療戦略Oral presentation
- The 19th Annual Academic Surgical Congress, English, Annual Academic Surgical Congress, Washington, D.C., United States, International conferenceClinical Significance of SUVmax on FDG-PET in Patients with Rectal Cancer Undergoing NACRTOral presentation
- 第207回近畿外科学会, Japanese, 関西医科大学 外科学講座, 枚方市, Japan, Domestic conference高齢の胃癌患者に対する術前化学療法の安全性についての検討Oral presentation
- 第207回近畿外科学会, Japanese, 関西医科大学 外科学講座, 枚方市, Japan, Domestic conferenceリンパ節郭清個数からみる MIE における上縦隔リンパ節郭清の重要性Oral presentation
- 日本消化器病学会近畿支部第120回例会, Japanese, 神戸大学大学院医学研究科外科学講座 肝胆膵外科学分野, 神戸, Japan, Domestic conference当院におけるTaTME併用大腸全摘術の手術成績Public symposium
- 第100回大腸癌研究会学術集会, Japanese, 東京女子医科大学 消化器・一般外科, 東京, Japan, Domestic conference下部進行直腸癌に対する術前化学放射線療法+選択的側方郭清の治療成績Poster presentation
- 第194回兵庫県外科医会学術集会, Japanese, 兵庫県外科医会, 神戸, Japan, Domestic conference十二指腸表在性腫瘍に対する腹腔鏡内視鏡合同手術における結腸間膜尾側からの腹腔鏡アプローチの有用性の検討Oral presentation
- 第36回日本バイオセラピィ学会学術集会総会, Japanese, 昭和大学医学部内科学講座腫瘍内科学部門, 東京, Japan, Domestic conference深層学習アルゴリズムに基づくイメージングサイトメトリーを用いた術前化学放射線療法後の直腸癌の新規予後因子の探索Oral presentation
- 第36回日本バイオセラピィ学会学術集会総会, Japanese, 昭和大学医学部内科学講座腫瘍内科学部門, 東京, Japan, Domestic conference大腸癌腫瘍免疫微小環境における CD4+T 細胞に与える肥満の影響Oral presentation
- 第36回日本内視鏡外科学会総会, Japanese, 秋田大学大学院医学系研究科 腎泌尿器科学講座, 横浜, Japan, Domestic conference安全な Collard 変法吻合を目指した変革と短期成績Oral presentation
- 第36回日本内視鏡外科学会総会, Japanese, 秋田大学大学院医学系研究科 腎泌尿器科学講座, 横浜, Japan, Domestic conference下部進行直腸癌に対する TaTME 併用の有用性とラーニングカーブに関する検討Oral presentation
- 第36回日本内視鏡外科学会総会, Japanese, 秋田大学大学院医学系研究科 腎泌尿器科学講座, 横浜, Japan, Domestic conferenceロボット支援食道切除における上縦隔リンパ節郭清手技と短期成績Oral presentation
- 第36回日本内視鏡外科学会総会, Japanese, 秋田大学大学院医学系研究科 腎泌尿器科学講座, 横浜, Japan, Domestic conferenceロボット支援胃切除術におけるリンパ節郭清時間の learning curveOral presentation
- 第36回日本内視鏡外科学会総会, Japanese, 秋田大学大学院医学系研究科 腎泌尿器科学講座, 横浜, Japan, Domestic conference多発リンパ節転移を伴う進行食道癌に対する Minimally invasive esophagectomyOral presentation
- 第36回日本内視鏡外科学会総会, Japanese, 秋田大学大学院医学系研究科 腎泌尿器科学講座, 横浜, Japan, Domestic conference経肛門アプローチ併用による2チーム側方郭清の手術手技と手術成績Public symposium
- 第36回日本内視鏡外科学会総会, Japanese, 秋田大学大学院医学系研究科 腎泌尿器科学講座, 横浜, Japan, Domestic conference人間工学に基づく「鏡視下クロソイド・カーブ針」の開発Oral presentation
- 第36回日本内視鏡外科学会総会, Japanese, 秋田大学大学院医学系研究科 腎泌尿器科学講座, 横浜, Japan, Domestic conferenceクロソイド・カーブ針で変わるロボット・内視鏡下縫合Public discourse
- 第44回日本肥満学会・第41回日本肥満症治療学会学術集会, Japanese, 東北大学大学院医学系研究科 糖尿病代謝内科学分野・岩手医科大学医学部内科学講座 糖尿病・代謝・内分泌内科分野, 仙台, Japan, Domestic conference当院における腹腔鏡下スリーブ状胃切除術の短期治療成績の検討Poster presentation
- 第34回日本消化器癌発生学会総会, Japanese, 群馬大学大学院医学系研究科 総合外科学講座 肝胆膵外科学分野, 高崎, Japan, Domestic conference深層学習アルゴリズムに基づくイメージングサイトメトリーを用いた術前化学放射線療法後の直腸癌の新規予後因子の探索Public symposium
- 第34回日本消化器癌発生学会総会, Japanese, 群馬大学大学院医学系研究科 総合外科学講座 肝胆膵外科学分野, 高崎, Japan, Domestic conference大腸癌手術前後における腸内細菌と代謝物の変化についての検討Public symposium
- 第34回日本消化器癌発生学会総会, Japanese, 群馬大学大学院医学系研究科 総合外科学講座 肝胆膵外科学分野, 高崎, Japan, Domestic conference放射線治療において抗腫瘍効果に寄与する腫瘍内CD8+T細胞の動態Public symposium
- 第74回日本気管食道科学会総会ならびに学術講演会, Japanese, 独立行政法人国立病院機構 九州がんセンター 消化管外科, 福岡, Japan, Domestic conference高齢者に対する食道切除後の腸瘻チューブ留置による栄養介入の重要性Oral presentation
- 第74回日本気管食道科学会総会ならびに学術講演会, Japanese, 独立行政法人国立病院機構 九州がんセンター 消化管外科, 福岡, Japan, Domestic conferenceリンパ節郭清個数からみるMinimally invasive esophagectomyにおける上縦隔リンパ節郭清の重要性Oral presentation
- 第26回腹腔鏡内視鏡合同手術研究会, Japanese, 神戸大学 食道胃腸外科・神戸大学 国際がん医療・研究センター 消化器内科, 神戸, Japan, Domestic conference十二指腸表在性腫瘍に対する腹腔鏡内視鏡合同⼿術における結腸間膜尾側からの腹腔鏡アプローチの有⽤性の検討Oral presentation
- IASGO-CME Advanced Post-Graduate Course in Kobe 2023, English, Department of Surgery, Hepato-Biliary-Pancreatic Surgery Division, Graduate School of Medicine, Kobe University, Kobe, Japan, International conferenceClinical Significance of SUVmax on FDG-PET to Predict Treatment Response and Outcomes in Patients with Rectal Cancer Undergoing NACRTPoster presentation
- IASGO-CME Advanced Post-Graduate Course in Kobe 2023, English, Department of Surgery, Hepato-Biliary-Pancreatic Surgery Division, Graduate School of Medicine, Kobe University, Kobe, Japan, International conferenceThe advantage of geriatric nutritional risk index as a prognostic indicator for elderly patients with early gastric cancer after noncurative endoscopic resectionPoster presentation
- The 3rd International Congress of the Asian Oncology Society (AOS2023), English, Department of Urology, Keio University School of Medicin, Yokohama, Japan, International conferenceThe significance of geriatric nutritional risk index as a prognostic factor for early gastric cancer in elderly patients after non-curative endoscopic resectionOral presentation
- The 3rd International Congress of the Asian Oncology Society (AOS2023), English, Department of Urology, Keio University School of Medicin, Yokohama, Japan, International conferenceAlbumin and derived neutrophil-to-lymphocyte ratio is a novel prognostic factor for patients with esophageal squamous cell carcinomaOral presentation
- The 3rd International Congress of the Asian Oncology Society (AOS2023), English, Department of Urology, Keio University School of Medicin, Yokohama, Japan, International conferenceClinical outcomes of neoadjuvant therapy followed by selective inguinal lymph node dissection and total mesorectal excision for metastasised low rectal cancerOral presentation
- 第33回近畿内視鏡下大腸手術研究会, Japanese, 近畿内視鏡下大腸手術研究会・株式会社ツムラ, 京都, Japan, Domestic conference特別講演Ⅱ「大腸癌に対するERASプロトコールにおける漢方製剤の役割」Others
- 第32回神戸内視鏡外科手術手技研究会, Japanese, 神戸内視鏡外科手術手技研究会・科研製薬株式会社・コヴィディエンジャパン株式会社, 神戸, Japan, Domestic conference特別講演「大腸癌に対する低侵襲手術(腹腔鏡手術、ロボット手術)~ 技術向上のために押さえておきたいポイント ~」Others
- 第36回近畿内視鏡外科研究会, Japanese, 近畿大学医学部外科学 下部消化管部門, 豊中, Japan, Domestic conference右肺腺癌虫垂転移に対して腹腔鏡下回盲部切除術を施行した1例Oral presentation
- 第36回近畿内視鏡外科研究会, Japanese, 近畿大学医学部外科学 下部消化管部門, 豊中, Japan, Domestic conference腹腔鏡下に切除し得た成人骨盤嚢胞性腫瘤の2例Oral presentation
- 第36回近畿内視鏡外科研究会, Japanese, 近畿大学医学部外科学 下部消化管部門, 豊中, Japan, Domestic conference下部直腸癌に対するTaTMEの有用性とラーニングカーブPublic symposium
- 第36回近畿内視鏡外科研究会, Japanese, 近畿大学医学部外科学 下部消化管部門, 豊中, Japan, Domestic conferenceワークショップ4 下部直腸癌に対して確実なTMEを行うための工夫Others
- 第36回近畿内視鏡外科研究会, Japanese, 近畿大学医学部外科学 下部消化管部門, 豊中, Japan, Domestic conferenceリンパ節転移比率からみるMinimally invasive esophagectomyにおける上縦隔リンパ節郭清の重要性Public symposium
- 第36回近畿内視鏡外科研究会, Japanese, 近畿大学医学部外科学 下部消化管部門, 豊中, Japan, Domestic conference当院におけるロボット支援下結腸切除術の導入 10例の経験Public symposium
- The Korea International Gastric Cancer Week 2023 (KINGCA WEEK 2023), English, The Korean Gastric Cancer Association, Seoul, Korea, Republic of, International conferenceThe advantage of geriatric nutritional risk index as a prognostic indictor for elderly patients with early gastric cancer after non-curative endoscopic resectionOral presentation
- The Korea International Gastric Cancer Week 2023 (KINGCA WEEK 2023), English, The Korean Gastric Cancer Association, Seoul, Korea, Republic of, International conferenceEfficacy of 18F-fluoro-2-deoxyglucose positron emission tomography as a predictor of treatment response to neoadjuvant chemotherapy for gastric cancerOral presentation
- 第16回兵庫大腸ビデオカンファレンス, Japanese, コヴィディエンジャパン株式会社, 神戸, Japan, Domestic conference司会Others
- the International Colorectal Research Summit 2023 (iCRS 2023), English, International Colorectal Research Summit, Seoul, Korea, Republic of, International conferenceAnatomical Landmark for Minimally Invasive ISR & APROral presentation
- 第3回神戸ラパロ道場, Japanese, コヴィディエンジャパン株式会社, 神戸, Japan, Domestic conference下部セッションOthers
- 第33回日本サイトメトリー学会学術集会, Japanese, 杏林大学大学院医学研究科 共同研究施設フロ−サイトメトリ−部門, Web, Japan, Domestic conference深層学習に基づくイメージサイトメトリーによる直腸癌の新規予後因子の探索Poster presentation
- 第3回OCCS, Japanese, 大鵬薬品工業株式会社, 那覇/Web, Japan, Domestic conference直腸癌手術APRにおけるランドマークを考えるOthers
- 第78回日本消化器外科学会総会, Japanese, 弘前大学大学院医学研究科消化器外科学講座, 函館, Japan, Domestic conference腹腔鏡下直腸癌手術症例が少ない施設における日本内視鏡外科学会技術認定取得医手術参加の有用性Oral presentation
- 第78回日本消化器外科学会総会, Japanese, 弘前大学大学院医学研究科消化器外科学講座, 函館, Japan, Domestic conference直腸癌の術前化学放射線療法への抵抗性における Wnt/β-catenin シグナル活性化の重要性Oral presentation
- 第78回日本消化器外科学会総会, Japanese, 弘前大学大学院医学研究科消化器外科学講座, 函館, Japan, Domestic conference高齢胃癌患者への内視鏡治療後非治癒切除症例における予後因子の検討Oral presentation
- 第78回日本消化器外科学会総会, Japanese, 弘前大学大学院医学研究科消化器外科学講座, 函館, Japan, Domestic conference当院における TaTME 併用大腸全摘術の手術成績の検討Public symposium
- 第78回日本消化器外科学会総会, Japanese, 弘前大学大学院医学研究科消化器外科学講座, 函館, Japan, Domestic conference術中診断にて漿膜浸潤以上の深達度であった進行胃癌に対する腹腔鏡下胃切除の安全性に関する検討Public symposium
- 第78回日本消化器外科学会総会, Japanese, 弘前大学大学院医学研究科消化器外科学講座, 函館, Japan, Domestic conference当院における進行胃癌に対するロボット支援下胃切除術の短期治療成績の検討Oral presentation
- 第78回日本消化器外科学会総会, Japanese, 弘前大学大学院医学研究科消化器外科学講座, 函館, Japan, Domestic conferenceASA 分類 Class 3 以上の大腸癌患者に対する腹腔鏡手術と開腹手術の比較検討Oral presentation
- 第78回日本消化器外科学会総会, Japanese, 弘前大学大学院医学研究科消化器外科学講座, 函館, Japan, Domestic conference高齢者食道癌患者に対する胸腔鏡下食道切除術Oral presentation
- 第78回日本消化器外科学会総会, Japanese, 弘前大学大学院医学研究科消化器外科学講座, 函館, Japan, Domestic conference短期・長期成績からみた下部直腸癌に対するTaTME の有用性についてOral presentation
- 第78回日本消化器外科学会総会, Japanese, 弘前大学大学院医学研究科消化器外科学講座, 函館, Japan, Domestic conference高齢者に対する胸腔鏡下食道切除後の経腸栄養は sarcopenia を予防できるか?Oral presentation
- 第78回日本消化器外科学会総会, Japanese, 弘前大学大学院医学研究科消化器外科学講座, 函館, Japan, Domestic conference鼠経転移を伴う直腸肛門腺癌に対する術前治療と選択的側方郭清の治療成績Oral presentation
- 第78回日本消化器外科学会総会, Japanese, 弘前大学大学院医学研究科消化器外科学講座, 函館, Japan, Domestic conference十二指腸浸潤を伴う胃癌に対する胃切除術の安全性の検討Oral presentation
- 第78回日本消化器外科学会総会, Japanese, 弘前大学大学院医学研究科消化器外科学講座, 函館, Japan, Domestic conferenceロボット支援下食道切除術の術者育成Oral presentation
- 第78回日本消化器外科学会総会, Japanese, 弘前大学大学院医学研究科消化器外科学講座, 函館, Japan, Domestic conferenceAI 組織診断を用いた術前化学放射線療法後直腸癌の腫瘍 CD8+T 細胞の評価法の開発とその応用Oral presentation
- 第78回日本消化器外科学会総会, Japanese, 弘前大学大学院医学研究科消化器外科学講座・小野薬品工業株式会社・ブリストルマイヤーズスクイブ株式会社, 函館, Japan, Domestic conference郭清を極める!エキスパートが考える 私の流儀Others
- 第99回大腸癌研究会学術集会, Japanese, 関西労災病院 外科・テルモ株式会社, 尼崎, Japan, Domestic conferenceLSD ランチョンセミナーD ①当院における低侵襲手術への取り組み ②大腸 MIS におけるわれわれのこだわりOthers
- 第99回大腸癌研究会学術集会, Japanese, 関西労災病院 外科・コヴィディエンジャパン株式会社, 尼崎, Japan, Domestic conference大腸癌に対するHybrid RASOthers
- 第99回大腸癌研究会学術集会, Japanese, 関西労災病院 外科, 尼崎, Japan, Domestic conference下部直腸癌に対するTaTMEの有用性とラーニングカーブOral presentation
- 第77回日本食道学会学術集会, Japanese, 近畿大学医学部 外科学教室上部消化管部門, 大阪, Japan, Domestic conference高齢者に対する腹臥位胸腔鏡下食道切除術Poster presentation
- 第77回日本食道学会学術集会, Japanese, 近畿大学医学部 外科学教室上部消化管部門, 大阪, Japan, Domestic conference食道胃接合部癌に対する腹腔鏡下経裂孔的再建における左横隔膜開放法の有用性Public symposium
- 第77回日本食道学会学術集会, Japanese, 近畿大学医学部 外科学教室上部消化管部門, 大阪, Japan, Domestic conference短期・長期成績からみたロボット支援食道切除術のエビデンスPublic symposium
- 第6回兵庫腹腔鏡下大腸切除研究会, Japanese, ジョンソン・エンド・ジョンソン株式会社, 神戸, Japan, Domestic conference【第一部】 ビデオクリニックOthers
- 第6回兵庫腹腔鏡下大腸切除研究会, Japanese, ジョンソン・エンド・ジョンソン株式会社, 神戸, Japan, Domestic conference開会の辞Others
- 第44回癌免疫外科研究会, Japanese, 千葉大学大学院医学研究院 先端応用外科, 千葉, Japan, Domestic conference大腸癌腫瘍免疫微小環境におけるCD4+T細胞に与える肥満の影響Oral presentation
- 第44回癌免疫外科研究会, Japanese, 千葉大学大学院医学研究院 先端応用外科, 千葉, Japan, Domestic conference化学放射線治療による腫瘍微小環境の変化~深層学習に基づくイメージサイトメトリーを用いた術前化学放射線療法後の直腸癌の新規予後因子の探索~Oral presentation
- The 15th International Gastric Cancer Congress (IGCC 2023), English, Department of Surgery, Keio University School of Medicine, Yokohama, Japan, Domestic conferenceNeutrophil lymphocyte ratio and histological response correlate with prognosis of gastric cancer undergoing neoadjuvant chemotherapyOthers
- The 15th International Gastric Cancer Congress (IGCC 2023), English, Department of Surgery, Keio University School of Medicine, Yokohama, Japan, Domestic conferenceSafety of laparoscopic gastrectomy for advanced gastric cancer with greater than serosal invasion depthOthers
- The 15th International Gastric Cancer Congress (IGCC 2023), English, Department of Surgery, Keio University School of Medicine, Yokohama, Japan, Domestic conferenceThe prognostic factors of early gastric cancer in elderly patients after non-curative endoscopic resectionOthers
- 第193回兵庫県外科医会学術集会, Japanese, 兵庫県外科医会, 神戸, Japan, Domestic conference難治性食道狭窄に対する腹腔鏡下食道バイパス術の工夫点と成績Oral presentation
- 第66回関西胸部外科学会学術集会, Japanese, JCHO大阪病院, 大阪, Japan, Domestic conference高齢者食道癌患者に対する胸腔鏡下食道切除術Public symposium
- 第66回関西胸部外科学会学術集会, Japanese, JCHO大阪病院, 大阪, Japan, Domestic conference進行食道癌に対するロボット支援下食道切除Public symposium
- 第48回日本外科系連合学会学術集会, Japanese, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, 横浜, Japan, Domestic conference食道切除 ・ 胸骨後再建後胃管切除に対する仰臥位胸腔鏡アプローチPoster presentation
- 第48回日本外科系連合学会学術集会, Japanese, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, 横浜, Japan, Domestic conferenceThe mGPS is a significant oncological marker of rectal cancer patients undergoing NACRT.Oral presentation
- 第48回日本外科系連合学会学術集会, Japanese, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, 横浜, Japan, Domestic conference切除不能進行胃癌に対する姑息的胃切除術の安全性に関する検討Oral presentation
- 第48回日本外科系連合学会学術集会, Japanese, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, 横浜, Japan, Domestic conference大量の難治性乳び腹水を伴う直腸間膜リンパ管嚢腫破裂に対して手術加療を施行した 1 例Others
- 第48回日本外科系連合学会学術集会, Japanese, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, 横浜, Japan, Domestic conference当院における TaTME 併用による大腸全摘術、 回腸嚢肛門吻合術の手術成績Public symposium
- 第48回日本外科系連合学会学術集会, Japanese, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, 横浜, Japan, Domestic conference高齢胃癌患者の内視鏡治療後非治癒切除症例における予後因子の検討Public symposium
- 第48回日本外科系連合学会学術集会, Japanese, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, 横浜, Japan, Domestic conference血行再建を伴う胸壁前有茎空腸再建術の有用性Public symposium
- 第48回日本外科系連合学会学術集会, Japanese, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, 横浜, Japan, Domestic conference膵臓側に位置する表在性非乳頭部十二指腸腫瘍に対する腹腔鏡内視鏡合同手術の工夫Public symposium
- 第48回日本外科系連合学会学術集会, Japanese, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, 横浜, Japan, Domestic conference自律神経を意識した腹臥位胸腔鏡下食道切除術Public symposium
- 第48回日本外科系連合学会学術集会, Japanese, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, 横浜, Japan, Domestic conferenceNACRT 後の直腸癌の腫瘍微小環境の変化~ AI を用いた新規予後因子の探索~Public symposium
- 第45回日本癌局所療法研究会, Japanese, 順天堂大学医学部・消化器外科学講座下部消化管外科, 東京, Japan, Domestic conference鼠径部転移を伴う直腸肛門腺癌に対する術前治療と選択的側方郭清の治療成績Oral presentation
- 第45回日本癌局所療法研究会, Japanese, 順天堂大学医学部・消化器外科学講座下部消化管外科, 東京, Japan, Domestic conference直腸癌の術前化学放射線療法への抵抗性における Wnt/ β -catenin シグナル活性化の重要性Oral presentation
- 第21回日本ヘルニア学会学術集会, Japanese, 大阪府済生会吹田病院へルニアセンター, 大阪, Japan, Domestic conference当科における全身合併症を伴う鼠径部ヘルニア手術の周術期管理の安全性の検討Public symposium
- 第77回手術手技研究会, Japanese, 愛知医科大学 消化器外科, 名古屋, Japan, Domestic conference難治性食道狭窄に対する腹腔鏡下食道バイパス術の工夫点と成績Public symposium
- 第77回手術手技研究会, Japanese, 愛知医科大学 消化器外科, 名古屋, Japan, Domestic conference当院における経肛門的アプローチ併用による大腸全摘出の手術手技Public symposium
- 第77回手術手技研究会, Japanese, 愛知医科大学 消化器外科, 名古屋, Japan, Domestic conference当院におけるロボット支援下胃切除術のメインデバイスの変遷Public symposium
- 第123回日本外科学会定期学術集会, Japanese, 東京慈恵会医科大学 外科学講座 血管外科, 東京, Japan, Domestic conferenceデジタルポスター(136) 大腸-合併症-1Others
- 第123回日本外科学会定期学術集会, Japanese, 東京慈恵会医科大学 外科学講座 血管外科, 東京, Japan, Domestic conferenceオープンソースの物体検出アルゴリズム YOLOv3 を用いた胸腔鏡下食道亜全摘術の手術動画解析Public symposium
- 第123回日本外科学会定期学術集会, Japanese, 東京慈恵会医科大学 外科学講座 血管外科, 東京, Japan, Domestic conference下部進行直腸癌に対する術前化学放射線療法と選択的側方郭清の治療成績Poster presentation
- 第123回日本外科学会定期学術集会, Japanese, 東京慈恵会医科大学 外科学講座 血管外科, 東京, Japan, Domestic conference食道切除後長期の腸瘻での栄養管理はサルコペニアを予防するPublic symposium
- 第123回日本外科学会定期学術集会, Japanese, 東京慈恵会医科大学 外科学講座 血管外科, 東京, Japan, Domestic conferenceAI 病理診断システムを用いた直腸癌の新規予後因子の探索Public symposium
- 第123回日本外科学会定期学術集会, Japanese, 東京慈恵会医科大学 外科学講座 血管外科, 東京, Japan, Domestic conference局所進行直腸癌術前療法における腫瘍内レジデントメモリー CD8+T 細胞の動態とその役割Public symposium
- 第123回日本外科学会定期学術集会, Japanese, 東京慈恵会医科大学 外科学講座 血管外科, 東京, Japan, Domestic conferenceDiversity からさらに未来へ~Diversity だけで十分ですか? ~Others
- 第123回日本外科学会定期学術集会, Japanese, 東京慈恵会医科大学 外科学講座 血管外科, 東京, Japan, Domestic conference経肛門アプローチによる側方郭清の標準化手術手技と手術成績Public symposium
- 第123回日本外科学会定期学術集会, Japanese, 東京慈恵会医科大学 外科学講座 血管外科, 東京, Japan, Domestic conference食道胃接合部癌に対する経裂孔的腹腔鏡下 y 字型食道胃管吻合の有用性Public symposium
- 第123回日本外科学会定期学術集会, Japanese, 東京慈恵会医科大学 外科学講座 血管外科, 東京, Japan, Domestic conference当院における胃・食道胃接合部腺癌に対する術前化学療法の治療成績の検討Public symposium
- 第123回日本外科学会定期学術集会, Japanese, 東京慈恵会医科大学 外科学講座 血管外科, 東京, Japan, Domestic conferencecStageIV 胃癌の conversion surgery における周術期化学療法の検討Public symposium
- 神戸消化器外科手術手技セミナー, Japanese, テルモ株式会社, 神戸/Web, Japan, Domestic conference一般演題 当科におけるアドスプレーの使用経験Others
- 神戸消化器外科手術手技セミナー, Japanese, テルモ株式会社, 神戸/Web, Japan, Domestic conference一般演題 当科におけるアドスプレー使用経験tp-APR を中心にOthers
- 第95回日本胃癌学会総会, Japanese, 静岡県立静岡がんセンター内視鏡科, 札幌, Japan, Domestic conference切除不能進行胃癌に対する姑息的胃切除術の安全性に関する検討Public symposium
- 第95回日本胃癌学会総会, Japanese, 静岡県立静岡がんセンター内視鏡科, 札幌, Japan, Domestic conference高齢の胃癌患者に対する術前化学療法の安全性の検討Poster presentation
- 第95回日本胃癌学会総会, Japanese, 静岡県立静岡がんセンター内視鏡科, 札幌, Japan, Domestic conference当院におけるCY1を伴う進行胃癌に対する集学的治療戦略Poster presentation
- 第95回日本胃癌学会総会, Japanese, 静岡県立静岡がんセンター内視鏡科, 札幌, Japan, Domestic conference胃癌切除例におけるpoorly cohesive carcinomaの臨床病理学的特徴と予後に関する検討Public symposium
- 第95回日本胃癌学会総会, Japanese, 静岡県立静岡がんセンター内視鏡科, 札幌, Japan, Domestic conference腹腔鏡下経裂孔アプローチにおける左横隔膜開放法による下縦隔郭清・再建の安全性に関する検討Poster presentation
- 第55回制癌剤適応研究会, Japanese, 横浜市立大学 消化器・腫瘍外科学, 鎌倉, Japan, Domestic conferenceStageIV胃癌のconversion surgeryにおける周術期化学療法と予後の検討Public symposium
- 第55回制癌剤適応研究会, Japanese, 横浜市立大学 消化器・腫瘍外科学, 鎌倉, Japan, Domestic conference放射線治療による腫瘍微小環境の変化~ AI組織解析システムを用いた術前化学放射線療法後の直腸癌の新規予後因子の探索~Public symposium
- The 18th Annual Academic Surgical Congress, English, Academic Surgical Congress · Association for Academic Surgery · Society of University Surgeons, Washington, DC, United States, Domestic conferenceThe mGPS is a significant oncological marker of rectal cancer patients undergoing NACRTOral presentation
- The 18th Annual Academic Surgical Congress, English, Academic Surgical Congress · Association for Academic Surgery · Society of University Surgeons, Washington, DC, United States, Domestic conferenceRisk factor for stricture after cervical triangular anastomosis in Minimally Invasive EsophagectomyOthers
- 第19回日本消化管学会総会学術集会, Japanese, 日本医科大学消化器内科学・日本医科大学付属病院消化器・肝臓内科, 東京, Japan, Domestic conference胃癌・食道胃接合部癌の術前化学療法効果診断における組織学的効果判定および宿主免疫指標マーカーの有用性の検討Public symposium
- 第98回大腸癌研究会学術集会, Japanese, 順天堂大学大学院医学研究科・人体病理病態学, 東京, Japan, Domestic conference当院における若年者大腸癌手術症例の検討Poster presentation
- Asian-Pacific Congress of Robotic Laparoscopic Surgery 2022 (ACRLS2022), English, Fujita Health University Hospital International Medical Center, Nagoya/web, Japan, Domestic conferenceHybrid abdominal robotic approach with TaTME for low rectal cancerPublic symposium
- 第35回日本内視鏡外科学会総会, Japanese, 藤田医科大学 先端ロボット・内視鏡手術学講座, 名古屋, Japan, Domestic conference難治性食道狭窄に対する腹腔鏡下食道バイパス術の工夫点と成績Oral presentation
- 第35回日本内視鏡外科学会総会, Japanese, 藤田医科大学 先端ロボット・内視鏡手術学講座, 名古屋, Japan, Domestic conference食道癌に対する腹臥位胸腔鏡下食道切除術の短期・長期成績Oral presentation
- 第35回日本内視鏡外科学会総会, Japanese, 藤田医科大学 先端ロボット・内視鏡手術学講座, 名古屋, Japan, Domestic conference腫瘍深達度が漿膜浸潤以上の進行胃癌に対する腹腔鏡下胃切除の安全性に関する検討Oral presentation
- 第35回日本内視鏡外科学会総会, Japanese, 藤田医科大学 先端ロボット・内視鏡手術学講座, 名古屋, Japan, Domestic conference直腸癌に対する Abdominal robotic approach 併用による Hybrid TaTMEOral presentation
- 第35回日本内視鏡外科学会総会, Japanese, 藤田医科大学 先端ロボット・内視鏡手術学講座, 名古屋, Japan, Domestic conference一般演題(口演) 26 下部 TaTME 1Others
- 第35回日本内視鏡外科学会総会, Japanese, 藤田医科大学 先端ロボット・内視鏡手術学講座, 名古屋, Japan, Domestic conferenceTransanal アプローチ併用側方郭清の治療成績と安全に行うための工夫Oral presentation
- 第35回日本内視鏡外科学会総会, Japanese, 藤田医科大学 先端ロボット・内視鏡手術学講座, 名古屋, Japan, Domestic conferenceコロンの理論、みんなで議論 ~安全で美しい腹腔鏡下大腸切除術・私の工夫~Others
- 第35回日本内視鏡外科学会総会, Japanese, 藤田医科大学 先端ロボット・内視鏡手術学講座, 名古屋, Japan, Domestic conference当科における残胃癌に対する腹腔鏡下残胃全摘術の手術成績と予後の検討Public symposium
- 第35回日本内視鏡外科学会総会, Japanese, 藤田医科大学 先端ロボット・内視鏡手術学講座, 名古屋, Japan, Domestic conferenceロボット支援食道切除の短期成績 - 胸腔鏡手術との比較 -Public symposium
- 第26回日本バイオ治療法学会学術集会, Japanese, 徳島大学大学院社会産業理工学研究部生物資源産業学域, 大阪, Japan, Domestic conferenceAI 病理診断システムを用いた直腸癌の新規予後因子の探索Oral presentation
- 第43回日本肥満学会・第40回日本肥満症治療学会学術集会, Japanese, 琉球大学大学院 医学研究科 内分泌代謝・血液・膠原病内科学講座(第二内科)・大分大学医学部 消化器・小児外科学講座, 那覇, Japan, Domestic conference肥満が大腸癌腫瘍微小環境のCD4陽性T細胞に及ぼす影響Oral presentation
- 第43回日本肥満学会・第40回日本肥満症治療学会学術集会, Japanese, 琉球大学大学院 医学研究科 内分泌代謝・血液・膠原病内科学講座(第二内科)・大分大学医学部 消化器・小児外科学講座, 那覇, Japan, Domestic conferenceCOVID19 感染下における腹腔鏡下スリーブ状胃切除術の導入と短期治療成績Oral presentation
- 第35回日本バイオセラピィ学会学術集会総会, Japanese, 福島県立医科大学 消化管外科学講座, 福島, Japan, Domestic conference大腸癌の腫瘍免疫微小環境における CD4 陽性T細胞に与える肥満の影響Oral presentation
- 第35回日本バイオセラピィ学会学術集会総会, Japanese, 福島県立医科大学 消化管外科学講座, 福島, Japan, Domestic conference放射線治療における腫瘍内 CD8+T細胞の動態Public symposium
- 第35回日本バイオセラピィ学会学術集会総会, Japanese, 福島県立医科大学 消化管外科学講座, 福島, Japan, Domestic conferenceAI イメージサイトメトリーを用いた直腸癌術前化学放射線療法の腫瘍 CD8+T 細胞の新たな評価法の開発Public symposium
- 第84回日本臨床外科学会総会, Japanese, 久留米大学医学部外科学講座, 福岡, Japan, Domestic conference周術期チーム医療による腹臥位胸腔鏡下食道切除術Public symposium
- 第52回胃外科・術後障害研究会, Japanese, 静岡県立静岡がんセンター 胃外科, 沼津/Web, Japan, Domestic conference残胃癌に対する腹腔鏡下残胃全摘術の手術成績の検討Public symposium
- 第52回胃外科・術後障害研究会, Japanese, 静岡県立静岡がんセンター 胃外科, 沼津/Web, Japan, Domestic conference幽門側胃切除後の残胃内容排出遅延に関する検討Public symposium
- 第52回胃外科・術後障害研究会, Japanese, 静岡県立静岡がんセンター 胃外科, 沼津/Web, Japan, Domestic conference術前欠損歯数が胃癌術後患者の予後に及ぼす影響についての検討Oral presentation
- 第33回日本消化器癌発生学会総会, Japanese, 東京大学大学院医学系研究科消化管外科学, 東京/Web, Japan, Domestic conference大腸癌のおけるCD4陽性T細胞の抗腫瘍免疫に及ぼす肥満の影響Public symposium
- 第33回日本消化器癌発生学会総会, Japanese, 東京大学大学院医学系研究科消化管外科学, 東京/Web, Japan, Domestic conference放射線治療において抗腫瘍効果に寄与する腫瘍内CD8+T細胞の動態Public symposium
- Annual Congress of KSS 2022 & 74th Congress of the Korean Surgical Society, English, Korean Surgical Society, Seoul, Korea, Republic of, Domestic conferenceLaparoscopic Endoscopic Cooperative Surgery Using Openwindow Suturing Technique for Treating Non-ampullary Superficial Duodenal Neoplasms Located on the Pancreatic SideOthers
- Annual Congress of KSS 2022 & 74th Congress of the Korean Surgical Society, English, Korean Surgical Society, Seoul, Korea, Republic of, Domestic conferenceComparison of Laparoscopic Gastrectomy for Gastric Cancer with 3D and 2D MonitorsPublic symposium
- 大腸技術認定医を目指す!-LAC定型化・手技向上を目指したZoom Webinar-, Japanese, ジョンソン・エンド・ジョンソン株式会社, 神戸/Web, Japan, Domestic conference症例提示Public symposium
- JDDW2022(第30回日本消化器関連学会週間), Japanese, 一般社団法人 日本消化器関連学会機構(JDDW), 福岡/Web, Japan, Domestic conference食道胃接合部に近接する胃消化管間質腫瘍に対する腹腔鏡下局所切除の安全性についての検討Poster presentation
- JDDW2022(第30回日本消化器関連学会週間), Japanese, 一般社団法人 日本消化器関連学会機構(JDDW), 福岡/Web, Japan, Domestic conferenceオープンソースの物体検出アルゴリズムYOLOv3を用いた胸腔鏡下食道亜全摘術の手術動画解析Poster presentation
- JDDW2022(第30回日本消化器関連学会週間), Japanese, 一般社団法人 日本消化器関連学会機構(JDDW), 福岡/Web, Japan, Domestic conference下部直腸癌に対するTaTMEの手術成績~Lap-TMEとの比較~Public symposium
- 第60回日本癌治療学会学術集会, Japanese, 群馬大学大学院医学系研究科総合外科学講座 肝胆膵外科分野, 神戸/Web, Japan, Domestic conference術前欠損歯数が胃癌術後患者の予後に及ぼす影響についての検討Oral presentation
- 第60回日本癌治療学会学術集会, Japanese, 群馬大学大学院医学系研究科総合外科学講座 肝胆膵外科分野, 神戸/Web, Japan, Domestic conferencecStageIV胃癌に対するconversion surgeryの手術成績と予後因子の検討Public symposium
- 第60回日本癌治療学会学術集会, Japanese, 群馬大学大学院医学系研究科総合外科学講座 肝胆膵外科分野, 神戸/Web, Japan, Domestic conference鼠経リンパ節転移を伴う直腸癌に対する術前治療と選択的鼠経郭清の臨床的意義Poster presentation
- 第60回日本癌治療学会学術集会, Japanese, 群馬大学大学院医学系研究科総合外科学講座 肝胆膵外科分野, 神戸/Web, Japan, Domestic conference術前化学療法における Alb/ dNLR の推移は食道癌の予後に関与するかPoster presentation
- 第60回日本癌治療学会学術集会, Japanese, 群馬大学大学院医学系研究科総合外科学講座 肝胆膵外科分野, 神戸/Web, Japan, Domestic conference直腸癌術前化学放射線療法の予後因子としての modified Glasgow Prognostic ScoreOral presentation
- 第60回日本癌治療学会学術集会, Japanese, 群馬大学大学院医学系研究科総合外科学講座 肝胆膵外科分野, 神戸/Web, Japan, Domestic conference直腸癌術前化学放射線療法における AI を用いた腫瘍組織 CD8+T 細胞の評価方法の検討Oral presentation
- 第60回日本癌治療学会学術集会, Japanese, 群馬大学大学院医学系研究科総合外科学講座 肝胆膵外科分野, 神戸/Web, Japan, Domestic conferenceFDG-PET/CTによる進行胃癌の病理学的病期の術前予測の有用性Poster presentation
- American College of Surgeons Clinical Congress 2022, English, American College of Surgeons, San Diego,CA, United States, Domestic conferenceEn-bloc Radical Lateral Pelvic Lymph Node Dissection Assisted By A Transanal ApproachOthers
- 第75回日本胸部外科学会定期学術集会, Japanese, 東京大学医学部附属病院 呼吸器外科, 横浜/Web, Japan, Domestic conference腹臥位胸腔鏡下食道切除術における腹部操作アプローチの比較(LAP vs HALS)Oral presentation
- 18th ISDE World Congress for Esophageal Diseases, English, International Society for Diseases of the Esophagus, Web, Japan, Domestic conferenceComparison of Laparoscopic Surgeries With or Without Hand-Assisted Procedure in the Abdominal Phase of Thoracoscopic Esophagectomy in the Prone PositionPoster presentation
- 第76回日本食道学会学術集会, Japanese, 東邦大学大学院消化器外科学講座・臨床腫瘍学講座, 東京/Web, Japan食道扁平上皮癌術前補助療法における治療前血清SCC抗原の意義Public symposium
- 第76回日本食道学会学術集会, Japanese, 東邦大学大学院消化器外科学講座・臨床腫瘍学講座, 東京/Web, Japanロボット支援食道切除術の利点と課題Poster presentation
- 第76回日本食道学会学術集会, Japanese, 東邦大学大学院消化器外科学講座・臨床腫瘍学講座, 東京/Web, JapanAlbumin-derived NLR score is a novel prognostic marker for esophageal squamous cell carcinomaPoster presentation
- 第76回日本食道学会学術集会, Japanese, 東邦大学大学院消化器外科学講座・臨床腫瘍学講座, 東京/Web, Japan胸腔鏡下食道切除症例における栄養介入としての腸瘻チューブ留置期間の検討Poster presentation
- 第76回日本食道学会学術集会, Japanese, 東邦大学大学院消化器外科学講座・臨床腫瘍学講座, 東京/Web, Japan腹臥位胸腔鏡下食道切除術における腹部操作アプローチの比較(LAP vs HALS)Oral presentation
- 第76回日本食道学会学術集会, Japanese, 東邦大学大学院消化器外科学講座・臨床腫瘍学講座, 東京/Web, Japan低侵襲と合併症リスクの低減を目指した腹腔鏡下胸骨後経路作成の術後成績Oral presentation
- 第15回兵庫大腸ビデオカンファレンス, Japanese, コヴィディエンジャパン株式会社, Web, Japan総合司会Public discourse
- 第35回近畿内視鏡外科研究会, Japanese, 兵庫医科大学消化器外科学講座上部消化管外科, 西宮, Japan, Domestic conference当院における右側結腸癌に対する体腔内吻合の導入と治療成績Oral presentation
- 第35回近畿内視鏡外科研究会, Japanese, 兵庫医科大学消化器外科学講座上部消化管外科, 西宮, Japan当院における右側結腸癌に対する対腔内吻合の導入と治療成績Oral presentation
- 第35回近畿内視鏡外科研究会, Japanese, 兵庫医科大学消化器外科学講座上部消化管外科, 西宮, JapanSiewert Ⅱ型接合部癌に対する経裂孔的アプローチによる下縦隔リンパ節郭清Public symposium
- 第35回近畿内視鏡外科研究会, Japanese, 兵庫医科大学消化器外科学講座上部消化管外科, 西宮, Japan食道切除・胸骨後再建後胃管切除に対する仰臥位胸腔鏡アプローチOral presentation
- 第35回近畿内視鏡外科研究会, Japanese, 兵庫医科大学消化器外科学講座上部消化管外科, 西宮, Japan膵・十二指腸・横行結腸浸潤を伴う胃癌に対し術前化学療法奏効後に腹腔鏡下幽門側胃切除術を施行した一例Oral presentation
- 第35回近畿内視鏡外科研究会, Japanese, 兵庫医科大学消化器外科学講座上部消化管外科, 西宮, Japan腹臥位胸腔鏡下食道切除における当科の郭清概念Public symposium
- 第35回近畿内視鏡外科研究会, Japanese, 兵庫医科大学消化器外科学講座上部消化管外科, 西宮, Japan大腸・小腸1Public discourse
- 第35回近畿内視鏡外科研究会, Japanese, 兵庫医科大学消化器外科学講座上部消化管外科, 西宮, Japan直腸癌手術におけるTaTMEの有用性Public symposium
- international Colorectal Research Summit (iCRS) 2022, English, Korean Society of Coloproctology, Web/誌上開催, Korea, Republic ofAbdominoperineal Resection: How Is It done?Public symposium
- Korea International Gastric Cancer Week 2022 (KINGCA WEEK 2022), English, The Korean Gastric Cancer Association, Web/誌上開催, Korea, Republic ofPreoperative Prediction of the Pathological Stage of Advanced Gastric Cancer by 18F-fluoro-2-deoxyglucose Positron Emission TomographyPublic symposium
- Korea International Gastric Cancer Week 2022 (KINGCA WEEK 2022), English, The Korean Gastric Cancer Association, Web/誌上開催, Korea, Republic ofAssessment of Risk Factors for Delayed Gastric Emptying After Distal Gastrectomy for Gastric CancerPublic symposium
- 第13回札幌医科大学腹腔鏡手術手技セミナー, Japanese, 札幌医科大学医学部 消化器・総合、乳腺・内分泌外科学講座, 札幌, Japan「腹腔鏡下S状結腸切除術(Lap-S)/腹腔鏡下側方郭清術(Laps-LLND)」、「計肛門的前腸間膜切除術(Ta-TME)」Invited oral presentation
- ゼロコン+シンポジウム Minimally I nvasive T herapies S eminar for Colorectal The 7th ON WEB, Japanese, コヴィディエンジャパン株式会社, Web, Japan側方リンパ節郭清Public discourse
- ゼロコン+シンポジウム Minimally I nvasive T herapies S eminar for Colorectal The 7th ON WEB, Japanese, コヴィディエンジャパン株式会社, Web, Japanビデオカンファレンス3 側方リンパ節郭清Public discourse
- ゼロコン+シンポジウム Minimally I nvasive T herapies S eminar for Colorectal The 7th ON WEB, Japanese, コヴィディエンジャパン株式会社, Web, Japanビデオカンファレンス1 横行結腸切除Public discourse
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, Japan食道胃接合部に近接する胃GISTに対する腹腔鏡下局所切除の安全性についての検討Oral presentation
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, Japan術前サルコペニアの層別化による短期・長期リスク評価の有用性Oral presentation
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, Japan80歳以上の大腸癌患者における腹腔鏡手術の有用性Oral presentation
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, Japan下部直腸癌手術におけるTaTMEの有用性Public symposium
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, Japan胃癌におけるFDG-PET検査によるリンパ節SUVmax値を用いたリンパ節転移診断の有用性の検討Oral presentation
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, Japan幽門側胃切除後の胃内容排出遅延の発症リスクと治療法に関する検討Oral presentation
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, Japan術前欠損歯数が胃癌術後患者の予後に及ぼす影響についての検討Oral presentation
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, Japan抗凝固療法中の患者に対する胃切除術の安全性についてOral presentation
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, Japan胸腔鏡下食道切除症例における腸瘻チューブ留置による栄養介入とその意義Public symposium
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, Japan当院における右側結腸癌に対する体腔内吻合の手術手技と短期成績Oral presentation
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, JapancStageⅣ胃癌に対するconversion surgeryの治療成績Public symposium
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, Japan胃癌大弯側リンパ節郭清時に周囲リンパ節の郭清ラインとの連続性を意識した#4sb郭清手技の有用性Public symposium
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, Japan低肺機能患者に対する腹臥位胸腔鏡下食道切除術Oral presentation
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, Japan直腸悪性腫瘍に対するHybrid手術の短期成績に関する後ろ向き研究Oral presentation
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, JapanSiewert II型食道胃接合部癌に対する偽His角・穹窿部を付加したy字様Overlap食道胃管吻合の有用性Public symposium
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, Japan頭側アプローチによる腹腔鏡下結腸右半切除~術者経験を考慮した段階的導入と定型化~Public symposium
- 第77回日本消化器外科学会総会, Japanese, 横浜市立大学消化器・腫瘍外科学, 横浜/Web, Japan一般演題007 大腸:taTMEPublic discourse
- 第77回日本消化器外科学会総会, English, 横浜市立大学消化器・腫瘍外科学, 東京/Web, JapanLaparoscopic retrosternal route creation for gastric conduit - efficacy and outcomes 腹腔鏡による胸骨後経路作成の工夫と術後成績Public symposium
- 第77回日本消化器外科学会総会, English, 横浜市立大学消化器・腫瘍外科学, 東京/Web, JapanDevelopment of a new method for evaluation of rectal cancer after neoadjuvant chemoradiotherapy 直腸癌術前化学放射線療法における腫瘍組織CD8+T細胞の新たな評価方法の開発Public symposium
- 第77回日本消化器外科学会総会, English, 横浜市立大学消化器・腫瘍外科学, 東京/Web, JapanA predictive nomogram model of therapeutic effect in neoadjuvant treatment for esophageal cancer 食道癌術前補助療法の奏効を予測するツールの開発;多施設共同後ろ向き観察研究Oral presentation
- 第77回日本消化器外科学会総会, English, 横浜市立大学消化器・腫瘍外科学, Suwon, Korea, Republic ofThe multicenter validation study of NAC response and recurrence patterns for esophageal cancer 切除可能進行食道癌における術前化学療法の奏効と再発形式の検証 -85施設3995例による多施設共同研究-Oral presentation
- 第2回神戸ラパロ道場, Japanese, コヴィディエンジャパン株式会社, Web, Japan下部セッションPublic discourse
- 第31回日本がん転移学会学術集会・総会, Japanese, 京都大学医学研究科, 京都/Web, Japan大腸癌腹膜播種モデルでは、PMN-MDSCが病態を進行させるPoster presentation
- 第97回大腸癌研究会学術集会, Japanese, 埼玉医科大学総合医療センター 消化管・一般外科, 東京/Web, Japan閉塞性大腸癌患者に対する腹腔鏡下手術の術前自己拡張型金属ステントの有用性Oral presentation
- 第106回北播外科医会, Japanese, 北播外科医会/科研製薬株式会社, 小野, Japan当科における直腸癌外科治療についてInvited oral presentation
- 第5回腹腔鏡下大腸切除研究会学術集会, Japanese, 一般社団法人 腹腔鏡下大腸切除研究会, 東京/Web, Japan直腸癌に対する経肛門鏡視下アプローチの腫瘍学的安全性について検討する多施設共同研究:Ta-Ta-Mi studyOral presentation
- 第44回日本癌局所療法研究会, Japanese, 独立行政法人 労働者健康安全機構 関西労災病院, 大阪, Japan遠隔転移を有するHER2陽性進行胃癌に対しConversion Surgeryを施行し奏効を得た1例Oral presentation
- 第44回日本癌局所療法研究会, Japanese, 独立行政法人 労働者健康安全機構 関西労災病院, 大阪, Japan食道癌に対するESD後の良性狭窄に対し食道バイパス手術によりQOL向上を得られた一例Oral presentation
- 第44回日本癌局所療法研究会, Japanese, 独立行政法人 労働者健康安全機構 関西労災病院, 大阪, Japan鼠径リンパ節転移陽性直腸癌に対する治療戦略と低侵襲手術Public discourse
- 第31回日本癌病態治療研究会, Japanese, 徳島大学消化器 移植外科学, 鳴門/Web, Japan術前化学療法における Alb-dNLR ratioの推移は食道癌の予後に関与するかPoster presentation
- 第31回日本癌病態治療研究会, Japanese, 徳島大学消化器 移植外科学, 鳴門/Web, Japan大腸癌免疫微小環境におけるCD4陽性T細胞に及ぼす肥満の影響Poster presentation
- 第31回日本癌病態治療研究会, Japanese, 徳島大学消化器 移植外科学, 鳴門/Web, Japan放射線治療における腫瘍内 CD8+T 細胞の動態Public symposium
- 第31回日本癌病態治療研究会, Japanese, 徳島大学消化器 移植外科学, 鳴門/Web, JapancStageIV胃癌に対するconversion surgeryの予後の検討Poster presentation
- 第31回日本癌病態治療研究会, Japanese, 徳島大学消化器 移植外科学, 鳴門/Web, Japan低侵襲治療を目指したロボット支援下胃切除術の導入と短期治療成績Poster presentation
- 第65回関西胸部外科学会学術集会, Japanese, 浜松医科大学 外科学第一講座, 浜松, Japan食道切除・胸骨後再建後胃管癌に対する仰臥位胸腔鏡アプローチPublic symposium
- 19thMESDA: Laparoscopic Colorectal Surgery 101, English, Mekong Endo Surgery Development Association, Suwon, Korea, Republic ofLaparoscopic Left hemicolectomy Laparoscopic Low Anterior ResectionOral presentation
- 19thMESDA: Laparoscopic Colorectal Surgery 101, English, Mekong Endo Surgery Development Association, 横浜/Web, JapanCurrent status of Transanal TMEPublic symposium
- AOS 2022(2nd International Congress of ASIAN ONCOLOGY SOCIETY), English, Asian Oncology Society, 横浜/Web, JapanThoracic cavity-to-cage ratio is a predictor of technical difficulties in minimally invasive esophagectomyPublic symposium
- 第5回兵庫腹腔鏡下大腸切除研究会, Japanese, ジョンソン・エンド・ジョンソン株式会社, Web, Japan閉会の辞Public discourse
- 第5回兵庫腹腔鏡下大腸切除研究会, Japanese, ジョンソン・エンド・ジョンソン株式会社, Web, Japan【第一部】ビデオクリニックPublic discourse
- 第43回癌免疫外科研究会, Japanese, 京都府立医科大学大学院医学研究科 消化器外科学, 京都, Japan腫瘍抗原導入樹状細胞にiNKT細胞リガンドを付加したワクチンは、抗原特異的な抗腫瘍免疫を効果的に誘導するPublic symposium
- 第43回癌免疫外科研究会, Japanese, 京都府立医科大学大学院医学研究科 消化器外科学, 京都, Japan大腸癌の腫瘍免疫微小環境におけるCD4陽性T細胞に及ぼす肥満の影響Public symposium
- 第43回癌免疫外科研究会, Japanese, 京都府立医科大学大学院医学研究科 消化器外科学, 京都, Japan放射線治療における腫瘍内CD8+T細胞の動態Public symposium
- 第76回手術手技研究会, Japanese, 佐賀大学医学部 一般・消化器外科, 佐賀/Web, Japan腹腔鏡による胸骨後経路作成の工夫と短期成績Public symposium
- 第29回神戸内視鏡外科手術手技研究会, Japanese, 神戸内視鏡外科手術手技研究会・科研製薬株式会社・コヴィディエンジャパン株式会社, 神戸/Web, Japan特別講演「大腸癌に対するロボット手術・腹腔鏡手術の現状と未来」Public discourse
- 第36回兵庫大腸癌治療研究会, Japanese, ミヤリサン製薬株式会社、大鵬薬品工業株式会社, Web, Japan【アンケート結果報告】大腸癌に対する手術及び化学療法の現状と遺伝子変異についてPublic discourse
- 第122回日本外科学会定期学術集会, Japanese, 熊本大学大学院 消化器外科学, 熊本市/Web, Japan術前化学療法におけるAlb/dNLRの推移は食道癌の予後に関与するかPublic symposium
- 第122回日本外科学会定期学術集会, Japanese, 熊本大学大学院 消化器外科学, 熊本市/Web, Japan術前欠損歯数が胃癌予後に及ぼす影響についての検討Poster presentation
- 第122回日本外科学会定期学術集会, Japanese, 熊本大学大学院 消化器外科学, 熊本市/Web, Japan食道胃接合部に近接する胃GISTに対する腹腔鏡下局所切除の安全性についての検討Poster presentation
- 第122回日本外科学会定期学術集会, Japanese, 熊本大学大学院 消化器外科学, 熊本市/Web, Japanサルコペニアの層別化によるリスク評価の有用性Poster presentation
- 第122回日本外科学会定期学術集会, Japanese, 熊本大学大学院 消化器外科学, 熊本市/Web, JapanMIE施行症例における術前血小板リンパ球比の予後予測因子としての有用性Public symposium
- 第122回日本外科学会定期学術集会, Japanese, 熊本大学大学院 消化器外科学, 熊本市/Web, Japan当科における下部進行直腸癌に対する治療戦略Public symposium
- 第122回日本外科学会定期学術集会, Japanese, 熊本大学大学院 消化器外科学, 熊本市/Web, Japan高齢胃癌患者への内視鏡治療後非治癒切除症例における予後の検討Poster presentation
- 第122回日本外科学会定期学術集会, Japanese, 熊本大学大学院 消化器外科学, 熊本市/Web, Japan胃・食道胃接合部癌術前化学療法における予後予測因子の検討Public symposium
- 第122回日本外科学会定期学術集会, Japanese, 熊本大学大学院 消化器外科学, 熊本市/Web, Japan2チームによるTaTMEは狭骨盤や肥満による腹腔鏡下直腸癌手術の困難さを緩和するPublic symposium
- 第122回日本外科学会定期学術集会, Japanese, 熊本大学大学院 消化器外科学, 熊本市/Web, Japan直腸癌術前化学放射線療法における腫瘍内レジデントメモリーCD8+T細胞の動態とその予後Public symposium
- 第122回日本外科学会定期学術集会, Japanese, 熊本大学大学院 消化器外科学, 熊本市/Web, Japan下部直腸癌に対するTaTMEと融合させたRobotic surgeryPublic symposium
- 第122回日本外科学会定期学術集会, Japanese, 熊本大学大学院 消化器外科学, 熊本市/Web, Japanデジタルポスター(148) 大腸-縫合不全Public discourse
- 第122回日本外科学会定期学術集会, Japanese, 熊本大学大学院 消化器外科学, 熊本市/Web, Japanロボット支援食道切除におけるlearning curveと手技の工夫Public symposium
- AACR ANNUAL MEETING 2022, English, American Association for Cancer Research, Seoul/Web, Korea, Republic ofPolymorphonuclear myeloid-derived suppressor cells reflect the status of peritoneal dissemination in colon cancer mouse modelOral presentation
- 第94回日本胃癌学会総会, Japanese, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, 横浜/Web, Japan幽門側胃切除後の胃内容排出遅延の発症リスクと治療法に関する検討Public symposium
- 第94回日本胃癌学会総会, Japanese, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, 横浜/Web, Japan抗血栓療法中の患者に対する胃癌手術の安全性の検討Poster presentation
- 第94回日本胃癌学会総会, Japanese, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, 横浜/Web, Japanda Vinci Harmonicによるロボット支援下幽門側胃切除術の時間短縮効果と短期治療成績の検討Oral presentation
- 第94回日本胃癌学会総会, English, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, New Orleans/Web, Korea, Republic ofPhase Ⅱ study of neoadjuvant chemotherapy for locally advanced gastric cancer in elderly patientsPoster presentation
- 第94回日本胃癌学会総会, English, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, 横浜/Web, JapanThe Signicance of Surgical Intervention Following Chemotherapy for Stage IV Gastric CancerOral presentation
- 第94回日本胃癌学会総会, English, 横浜市立大学附属市民総合医療センター 消化器病センター 外科, 横浜/Web, JapanSafety management of laparoscopic endoscopic cooperative surgery for duodenal tumorPublic symposium
- 第14回日本ロボット外科学会学術集会, Japanese, 鹿児島大学医学部産科婦人科, Web, Japanロボット支援食道切除における反回神経麻痺低減の試みPublic symposium
- ゼロコン+シンポジウム, Japanese, コヴィディエンジャパン株式会社, Web, JapanTransanal approach 直腸癌に対する経肛門的直腸間膜切除術を学ぶ-改めて導入編-Public discourse
- 第54回制癌剤適応研究会, Japanese, 富山大学消化器・腫瘍・総合外科, Web/誌上開催, Japan癌幹細胞マーカーは食道扁平上皮癌に対する術前化学療法の治療効果予測に有用であるPublic symposium
- 第54回制癌剤適応研究会, Japanese, 富山大学消化器・腫瘍・総合外科, Web/誌上開催, Japan大腸癌腹膜播種モデルにおける骨髄由来免疫抑制細胞の機能Public symposium
- 第54回制癌剤適応研究会, Japanese, 富山大学消化器・腫瘍・総合外科, Web/誌上開催, Japan術前化学療法を施行した食道癌切除症例の予後を予測するバイオマーカーとしての血小板-リンパ球比の意義Public symposium
- 第18回日本消化管学会総会学術集会, Japanese, 東京大学大学院医学系研究科消化管外科学, 東京/Web, Japan癌関連線維芽細胞および癌細胞で発現する Metallothionein 2A は食道扁平上皮癌の進展に関与するPublic symposium
- 第18回日本消化管学会総会学術集会, Japanese, 東京大学大学院医学系研究科消化管外科学, 東京/Web, Japanマクロファージとの相互作用により発現誘導される S100A8/A9 は Akt、p38 を介して食道扁平上皮癌細胞の運動能、浸潤能を亢進させるPublic symposium
- 17th Annual Acasemic Surgical Congress, English, Academic Surgical Congress · Association for Academic Surgery · Society of University Surgeons, Florida/Web, United StatesAssessing The Risk Factors for Delayed Gastric Emptying after Distal Gastrectomy for Gastric CancerOral presentation
- エネルギーデバイスを語ろう~私の超音波凝固切開装置の使い方~, Japanese, コヴィディエンジャパン株式会社, Web, Japan大腸領域Oral presentation
- 第96回大腸癌研究会, Japanese, 帝京大学医学部外科学講座, 東京/Web, Japan当科における経肛門アプローチ併用による側方リンパ節郭清の手術成績Oral presentation
- 第34回日本内視鏡外科学会総会, Web開催/神戸, Domestic conference低肺機能に対する腹臥位胸腔鏡下食道切除術Oral presentation
- 第34回日本内視鏡外科学会総会, Web開催/神戸, Domestic conferenceロボット支援食道切除術においてenergy deviceが短期成績に及ぼす影響Public symposium
- 第34回日本内視鏡外科学会総会, Web開催/神戸, Domestic conference左結腸動脈処理に着目した腹腔鏡下左側結腸癌手術Oral presentation
- 第34回日本内視鏡外科学会総会, Web開催/神戸, Domestic conference当院における右側結腸癌に対する体腔内吻合の導入と治療成績Oral presentation
- 第34回日本内視鏡外科学会総会, Web開催/神戸, Domestic conference腹腔鏡下胃切除症例における周術期抗血栓療法の安全性の検討Oral presentation
- 第34回日本内視鏡外科学会総会, Web開催/神戸, Domestic conference当院におけるロボット支援下幽門側胃切除術の手技定型化の確立と短期治療成績Oral presentation
- 第34回日本内視鏡外科学会総会, Web開催/神戸, Domestic conferenceロボット支援食道手術による反回神経麻痺の軽減に関する試みOral presentation
- 第34回日本内視鏡外科学会総会, Web開催/神戸, Domestic conference直腸悪性腫瘍に対するHybird abdominal robotic approach with conventional TaTMEの導入Public symposium
- 第34回日本内視鏡外科学会総会, Web開催/神戸, Domestic conference直腸癌手術におけるTransanal minimally invasive ISRの有用性と課題Oral presentation
- 第34回日本内視鏡外科学会総会, Web開催/神戸, Domestic conferenceTaTME手術におけるNew Option ―機器が切り開く可能性―Public discourse
- 第34回日本内視鏡外科学会総会, Web開催/神戸, Domestic conference直腸癌手術におけるRobotic surgeryとTransanal approachの融合Public discourse
- 第34回日本内視鏡外科学会総会, Web開催/神戸, Domestic conferenceロボット支援食道切除における至適剥離層Public symposium
- 第32回日本消化器癌発生学会総会/第10回国際消化器癌発生会議, Web開催, Domestic conference直腸癌に対するAbdominal robotic approach併用によるHybrid TaTMEPoster presentation
- 第32回日本消化器癌発生学会総会/第10回国際消化器癌発生会議, Web開催, Domestic conference大腸癌術後の早期再発のリスク因子Poster presentation
- 第32回日本消化器癌発生学会総会/第10回国際消化器癌発生会議, Web開催, Domestic conference癌幹細胞マーカーは、食道扁平上皮癌に対する術前化学療法の治療効果予測に有用であるPoster presentation
- 第32回日本消化器癌発生学会総会/第10回国際消化器癌発生会議, Web開催, Domestic conference腫瘍抗原導入樹状細胞にα-GalCerを付加したワクチンベクターの抗腫瘍効果Poster presentation
- 第32回日本消化器癌発生学会総会/第10回国際消化器癌発生会議, Web開催, Domestic conference術前化学療法を施行した食道癌切除症例の予後を予測するバイオマーカーとしての血小板-リンパ球比の意義Poster presentation
- 第32回日本消化器癌発生学会総会/第10回国際消化器癌発生会議, Web開催, Domestic conference当科におけるStageⅣ胃癌に対するconversion surgeryの治療成績Poster presentation
- 第30回日本コンピュータ外科学会大会, Web開催/つくば, Domestic conference胸腔鏡下食道切除術における3D内視鏡システムは術後短期成績の改善に寄与するOral presentation
- 第30回日本コンピュータ外科学会大会, Web開催/つくば, Domestic conferenceロボット支援食道切除手術におけるlearning curveOral presentation
- 第30回日本コンピュータ外科学会大会, Web開催/つくば, Domestic conference3D/HDおよび2D/4Kモニターが術者技術レベルごとの手術操作にもたらす影響Oral presentation
- 第30回日本コンピュータ外科学会大会, Web開催/つくば, Domestic conference3D‒CT を用いた骨盤計測と直腸癌手術時間との関連―通常の腹腔鏡下手術と Transanal Total Mesorectal Excision との違い―Oral presentation
- 第72回日本気管食道科学会総会ならびに学術講演会, Web開催, Domestic conferenceオープンソースの物体検出アルゴリズムYOLOv3を用いた胸腔鏡下食道亜全摘術の手術動画解析Public symposium
- 第72回日本気管食道科学会総会ならびに学術講演会, Web開催, Domestic conference胸腔鏡下食道切除術における嚥下性肺炎の予防Public symposium
- 第51回胃外科・術後障害研究会, Web開催, Domestic conference幽門側胃切除後の残胃内容排出遅延に関する検討Oral presentation
- 第51回胃外科・術後障害研究会, Web開催, Domestic conference高齢者胃癌術後の肺炎併発が長期予後へ与える影響の検討Oral presentation
- JDDW2021(第29回日本消化器関連学会週間), Web開催/神戸, Domestic conference患者由来大腸癌オルガノイドを用いたバルプロ酸の新規治療薬としての有用性の検討Poster presentation
- 第22回腹腔鏡内視鏡合同研究会, Web開催, Domestic conference膵臓側に位置する表在性非乳頭部十二指腸に対する腹腔鏡内視鏡合同手術の工夫Oral presentation
- 第59回日本癌治療学会学術集会, Web開催/横浜, Domestic conferenceTaTMEを軸とした近未来の下部直腸癌手術Public symposium
- 日本外科代謝栄養学会第58回学術集会, Web開催/神戸, Domestic conference胃癌手術症例における欠損歯が予後に及ぼす影響についてOral presentation
- 日本外科代謝栄養学会第58回学術集会, Web開催/神戸, Domestic conference食道癌患者における術前のサルコペニア予測サロゲートマーカーの開発Oral presentation
- 第27回外科侵襲とサイトカイン研究会, Web開催/神戸, Domestic conference大腸癌免疫微小環境におけるCD4陽性T細胞に及ぼす肥満の影響Public symposium
- 17th ISDE World Congress for Esophageal Diseases(ISDE2021), Web開催, International conferenceProne Thoracoscopic Esophagectomy for Patients with Low Pulmonary FunctionOral presentation
- 17th ISDE World Congress for Esophageal Diseases(ISDE2021), Web開催, International conferenceLaparoscopic creation of retrosternal route for gastric conduit reconstruction; safe and feasible procedureOral presentation
- 17th ISDE World Congress for Esophageal Diseases(ISDE2021), Web開催, International conferenceA case of G-CSF(granulocyte-colony stimulating factor) producing esophageal cancer with enteroblastic differentiationPoster presentation
- 17th ISDE World Congress for Esophageal Diseases(ISDE2021), Web開催, International conferenceThoracoscopic retrosternal gastric conduit resection in the supine position for gastric tube cancerOral presentation
- 17th ISDE World Congress for Esophageal Diseases(ISDE2021), Web開催, International conferenceSurgical techniques and potential of mediastinal lymphadenectomy in robotic surgeryOral presentation
- 第34回近畿内視鏡外科研究会, Web開催, Domestic conferenceロボット支援食道切除術の短期成績と learning curveOral presentation
- 第34回近畿内視鏡外科研究会, Web開催, Domestic conference腹臥位胸腔鏡下食道切除術における上縦隔郭清手技の工夫と定型化Oral presentation
- 第34回近畿内視鏡外科研究会, Web開催, Domestic conference当院における腹腔鏡下胃切除を安全に行うためのちょっとした工夫Public symposium
- 第34回近畿内視鏡外科研究会, Web開催, Domestic conference直腸癌手術における Robotic TaTME の可能性Public symposium
- 第34回近畿内視鏡外科研究会, Web開催, Domestic conference当科におけるロボット支援食道手術の課題と可能性Public symposium
- 第75回日本食道学会学術集会, Web開催/東京, Domestic conferenceLaparoscopic retrosternal route creation; short-term postoperative outcomesPoster presentation
- 第75回日本食道学会学術集会, Web開催/東京, Domestic conferenceSafety and validity of thoracoscopic esophagectomy for elderly patientsPublic symposium
- 第75回日本食道学会学術集会, Web開催/東京, Domestic conferenceEstablished upper mediastinum lymphadenectomy in prone MIE improves outcomesOral presentation
- 第75回日本食道学会学術集会, Web開催/東京, Domestic conferenceValidity of lymphadenectomy for No.106recL estimated by Efficacy IndexPublic symposium
- 第30回消化器疾患病態治療研究会, Web開催, Domestic conference直腸癌術後縫合不全は長期予後を悪化させるのか?マウスモデルと臨床研究で得られた結果からの考察Oral presentation
- 第30回日本がん転移学会学術集会・総会, Web開催, Domestic conferenceFDG-PET検査によるリンパ節SUVmax値を用いた胃癌リンパ節転移診断の有用性の検討Poster presentation
- 第30回日本がん転移学会学術集会・総会, Web開催, Domestic conferenceStageIV切除不能胃癌に対する外科治療Public symposium
- 第30回日本がん転移学会学術集会・総会, Web開催, Domestic conference大腸癌腹膜播種モデルにおけるPMN-MDSCの役割Poster presentation
- 第76回日本消化器外科学会総会, Web開催/京都, Domestic conferenceShort-Term Outcomes of Robot-Assisted Minimally invasive esophagectomyPublic symposium
- 第76回日本消化器外科学会総会, Web開催/京都, Domestic conference飽和食塩溶液固定法を用いたCadaver Surgical Trainingの有用性Public symposium
- 第76回日本消化器外科学会総会, Web開催/京都, Domestic conference腹腔鏡による胸骨後経路作成の工夫と短期成績Oral presentation
- 第76回日本消化器外科学会総会, Web開催/京都, Domestic conference食道癌患者における術前のサルコペニア予測サロゲートマーカーの開発と臨床的意義Oral presentation
- 第76回日本消化器外科学会総会, Web開催/京都, Domestic conference至適術前治療選択のためのバイオマーカーの重要性Oral presentation
- 第76回日本消化器外科学会総会, Web開催/京都, Domestic conference当院における胃・食道胃接合部癌に対する術前化学療法の治療成績の検討Oral presentation
- 第76回日本消化器外科学会総会, Web開催/京都, Domestic conferenceEstablished upper mediastinum lymphadenectomy in prone MIE improves outcomesPublic symposium
- 第76回日本消化器外科学会総会, Web開催/京都, Domestic conference直腸癌術後縫合不全は長期予後を悪化させるか?マウスモデルと臨床多施設共同研究で得られた結果からの考察Public symposium
- 第76回日本消化器外科学会総会, Web開催/京都, Domestic conferenceSimple and reliable transhiatal laparoscopic reconstruction for Siewert type II tumorPublic symposium
- 第76回日本消化器外科学会総会, Web開催/京都, Domestic conference直腸癌術前化学放射線療法におけるCD8+T細胞の誘導とその予後Oral presentation
- 第76回日本消化器外科学会総会, Web開催/京都, Domestic conferencetaTMEを安全に行うための工夫と手術成績,そして今後の展望Public symposium
- 第76回日本消化器外科学会総会, Web開催/京都, Domestic conference一般演題14 大腸:直腸 TaTME1Others
- 第76回日本消化器外科学会総会, Web開催/京都, Domestic conferencePotential of robotic surgery surpassing conventional thoracoscopic esophagectomyPublic symposium
- 第31回日本サイトメトリー学会学術集会, Web開催, Domestic conference放射線治療における腫瘍内CD8⁺T細胞の動態Oral presentation
- 第31回日本サイトメトリー学会学術集会, Web開催, Domestic conference大腸癌腹膜播腫モデルにおける骨髄由来免疫抑制細胞の機能Oral presentation
- 第46回日本外科系連合学会学術集会, Web開催/東京, Domestic conferenceAbdominal robotic approach 併用によるHybrid taTMEの安全性Public symposium
- 第46回日本外科系連合学会学術集会, Web開催/東京, Domestic conference当院におけるロボット支援下幽門側胃切除術の短期治療成績と定型化に向けた取り組みPublic symposium
- 第46回日本外科系連合学会学術集会, Web開催/東京, Domestic conference食道癌術後患者においてcomprehensive complication indexが予後に及ぼす影響Public symposium
- 第64回関西胸部外科学会学術集会, Web開催, Domestic conference高齢食道癌患者に対する胸腔鏡下食道切除術の安全性と妥当性Oral presentation
- 第43回日本癌局所療法研究会, Web開催, Domestic conference右水腎症を伴う進行直腸癌に対し術前化学療法を施行し、病理学的完全奏功を得た1例Oral presentation
- 第75回手術手技研究会, Web開催/三島, Domestic conference食道切除・胸骨後再建後胃管癌に対する仰臥位胸腔鏡アプローチOral presentation
- 第75回手術手技研究会, Web開催/三島, Domestic conferencetaTMEの手術成績と手技の工夫Poster presentation
- 第75回手術手技研究会, Web開催/三島, Domestic conference十二指腸乳頭に近接する表在型腫瘍に対する乳頭損傷予防として膵管ステントを用いた腫瘍切除術式の検討Poster presentation
- 第121回日本外科学会定期学術集会, Web開催, Domestic conference低肺機能食道癌患者に対する腹臥位胸腔鏡下食道切除術の安全性Oral presentation
- 第121回日本外科学会定期学術集会, Web開催, Domestic conference高齢者の胃癌ESD後追加外科切除に関する検討Poster presentation
- 第121回日本外科学会定期学術集会, Web開催, Domestic conference当科におけるcStageIV胃癌に対するconversion surgeryの治療成績Poster presentation
- 第121回日本外科学会定期学術集会, Web開催, Domestic conferenceFDG-PET検査によるリンパ節SUVmax値を用いた胃癌リンパ節転移診断の有用性の検討Public symposium
- 第121回日本外科学会定期学術集会, Web開催, Domestic conference直腸癌NACRT症例におけるサルコペニアの影響Public symposium
- 第121回日本外科学会定期学術集会, Web開催, Domestic conference食道癌におけるcomprehensive complication indexと長期予後の関係Oral presentation
- 第121回日本外科学会定期学術集会, Web開催, Domestic conferenceリンパ節転移比率はMinimally invasive esophagectomy(MIE)を施行した食道扁平上皮癌患者の独立予後因子であるOral presentation
- 第121回日本外科学会定期学術集会, Web開催, Domestic conference当科における胃腺癌・食道胃接合部腺癌に対する術前化学療法の治療成績Poster presentation
- 第121回日本外科学会定期学術集会, Web開催, Domestic conference最新内視鏡システムが腹腔鏡下胃癌手術にもたらすものPublic symposium
- 第121回日本外科学会定期学術集会, Web開催, Domestic conference大腸癌腹膜播腫モデルにおける PD-L1 耐性とその克服Oral presentation
- 第121回日本外科学会定期学術集会, Web開催, Domestic conference直腸癌におけるtransperineal minimally invasive APRの有用性:手術成績と定型化についてOral presentation
- 第121回日本外科学会定期学術集会, Web開催, Domestic conference当科で行っている胸管温存,反回神経非遊離のen-bloc 縦隔郭清Oral presentation
- 第13回兵庫大腸ビデオカンファレンス, Japanese, コヴィデイエンジャパン株式会社, web開催, Japan, Domestic conference情報提供Others
- 第13回兵庫大腸ビデオカンファレンス, Japanese, コヴィデイエンジャパン株式会社, web開催, Japan, Domestic conference司会Others
- 第33回日本内視鏡外科学会総会, Japanese, 大分大学医学部消化器・小児外科学講座, 横浜/web開催, Japan, Domestic conferenceComputer-based video analysis of device usage in laparoscopic gastrectomy.Public symposium
- 第33回日本内視鏡外科学会総会, Japanese, 大分大学医学部消化器・小児外科学講座, 横浜/web開催, Japan, Domestic conferenceProne thoracoscopic esophagectomy for patients with low respiratory functionOral presentation
- 第33回日本内視鏡外科学会総会, Japanese, 大分大学医学部消化器・小児外科学講座, 横浜/web開催, Japan, Domestic conferenceRobot-assisted gastrectomy: short-term outcomes and procedural standardization at a single hospitalOral presentation
- 第33回日本内視鏡外科学会総会, Japanese, 大分大学医学部消化器・小児外科学講座, 横浜/web開催, Japan, Domestic conferenceHow much operative time does transanal approach reduce for male patients with rectal cancer?Public symposium
- 第33回日本内視鏡外科学会総会, Japanese, 大分大学医学部消化器・小児外科学講座, 横浜/web開催, Japan, Domestic conferenceLaparoscopic vs. open right hemicolectomy: the Japanese National Clinical Database analysisPublic symposium
- 第33回日本内視鏡外科学会総会, Japanese, 大分大学医学部消化器・小児外科学講座, 横浜/web開催, Japan, Domestic conferenceTransanal vs. laparoscopic TME for low rectal cancer: clinical outcomes and technical tipsPublic symposium
- 第33回日本内視鏡外科学会総会, Japanese, 大分大学医学部消化器・小児外科学講座, 横浜/web開催, Japan, Domestic conferenceWhich surgical position is beneficial for thoracoscopic esophagectmoy?-Prone or lateral position-Poster presentation
- 第33回日本内視鏡外科学会総会, Japanese, 大分大学医学部消化器・小児外科学講座, 横浜/web開催, Japan, Domestic conference外側穿孔剥離による安全なTaTMEの実践と応用Public discourse
- 第93回日本胃癌学会総会, Japanese, 大阪市立大学大学院 医学研究科 消化器外科学, web開催, Japan, Domestic conference抗血栓療法中の患者に対する胃癌手術の安全性の検討Oral presentation
- 第93回日本胃癌学会総会, Japanese, 大阪市立大学大学院 医学研究科 消化器外科学, web開催, Japan, Domestic conference当院におけるロボット支援下幽門側胃切除術の短期治療成績と定型化に向けた取り組みOral presentation
- 第93回日本胃癌学会総会, Japanese, 大阪市立大学大学院 医学研究科 消化器外科学, web開催, Japan, Domestic conference高齢者に対する胃癌ESD後追加手術Public symposium
- 第93回日本胃癌学会総会, Japanese, 大阪市立大学大学院 医学研究科 消化器外科学, web開催, Japan, Domestic conference高齢進行胃・接合部癌患者に対する術前化学療法の安全性と有用性の検討Public symposium
- 第93回日本胃癌学会総会, Japanese, 大阪市立大学大学院 医学研究科 消化器外科学, web開催, Japan, Domestic conference術前化学療法を行いpCRを得られた6症例の検討Poster presentation
- 第93回日本胃癌学会総会, Japanese, 大阪市立大学大学院 医学研究科 消化器外科学, web開催, Japan, Domestic conference高齢者の胃癌に対する胃切除範囲の予後に及ぼす影響Oral presentation
- 第45回日本外科系連合学会学術集会, Japanese, 久留米大学病院 腫瘍センター, web開催, Japan, Domestic conference女性外科医のキャリア・アップを目指した一歩踏み込んだサポート体制Public symposium
- 第75回日本消化器外科学会総会, Japanese, 和歌山県立医科大学外科学第2講座, 和歌山/Web開催, Japan, Domestic conferenceStandardization of upper mediastinal lymphadenectomy in prone thoracoscopic esophagectomy(腹臥位胸腔鏡下食道切除術における上縦隔郭清の定型化)Public symposium
- 第75回日本消化器外科学会総会, Japanese, 和歌山県立医科大学外科学第2講座, 和歌山/Web開催, Japan, Domestic conferenceComparison of 3D and 4K for laparoscopic gastrectomy for gastric cancer(腹腔鏡下胃癌手術の手術成績に関する内視鏡画像システム(3Dvs4K)のランダム化比較試験)Public symposium
- 第75回日本消化器外科学会総会, Japanese, 和歌山県立医科大学外科学第2講座, 和歌山/Web開催, Japan, Domestic conferenceSurgical outcomes and technical tips of transanal total mesorectal excision for low rectal cancer (下部直腸癌に対するtaTMEの手術成績(vs. lap TME)と安全に行うための工夫)Public symposium
- 第75回日本消化器外科学会総会, Japanese, 和歌山県立医科大学外科学第2講座, 和歌山/Web開催, Japan, Domestic conferenceFeasibility of thoracic duct preservation in esophageal SCC: a propensity score matchied-cohort study(食道扁平上皮癌に対する食道切除における胸管温存の妥当性~傾向スコアを用いた後ろ向きコホート研究~)Public symposium
- 第75回日本消化器外科学会総会, Japanese, 和歌山県立医科大学外科学第2講座, 和歌山/Web開催, Japan, Domestic conferenceStandardization of the robotic esophagectomy based on standardized minimally invasive esophagectomy(胸腔鏡手術との互換性から考えるロボット支援下食道切除術への移行と定型化)Public symposium
- 第75回日本消化器外科学会総会, Japanese, 和歌山県立医科大学外科学第2講座, 和歌山/Web開催, Japan, Domestic conference腹腔鏡下胃切除術動画における手術器具自動認識システムの開発と臨床研究への応用Public symposium
- 第75回日本消化器外科学会総会, Japanese, 和歌山県立医科大学外科学第2講座, 和歌山/Web開催, Japan, Domestic conference腹腔鏡による安全な胸骨後経路作成の工夫Oral presentation
- 第75回日本消化器外科学会総会, Japanese, 和歌山県立医科大学外科学第2講座, 和歌山/Web開催, Japan, Domestic conference当院におけるロボット支援下胃切除術の短期治療成績と定型化に向けた取り組みOral presentation
- 第75回日本消化器外科学会総会, Japanese, 和歌山県立医科大学外科学第2講座, 和歌山/Web開催, Japan, Domestic conference臨床的側方リンパ節転移陽性直腸癌に対する術前化学放射線療法に伴う直腸癌手術後の再発リスクの検討Public symposium
- 第75回日本消化器外科学会総会, Japanese, 和歌山県立医科大学外科学第2講座, 和歌山/Web開催, Japan, Domestic conference局所進行胃癌に対する術前化学療法著効症例において術後補助化学療法は省略可能かOral presentation
- 第75回日本消化器外科学会総会, Japanese, 和歌山県立医科大学外科学第2講座, 和歌山/Web開催, Japan, Domestic conference腹膜播種における骨髄由来免疫抑制性細胞の働きとその治療応用Oral presentation
- 第75回日本消化器外科学会総会, Japanese, 和歌山県立医科大学外科学第2講座, 和歌山/Web開催, Japan, Domestic conference一般演題122 大腸:イレウス1Others
- 第75回日本消化器外科学会総会, Japanese, 和歌山県立医科大学外科学第2講座, 和歌山/Web開催, Japan, Domestic conference高度進行胃癌に対するConversion surgeryの検討Public symposium
- 第74回日本食道学会学術集会, Japanese, 徳島大学大学院医歯薬学研究部 胸部・内分泌・腫瘍外科学分野, 徳島/Web開催, Japan, Domestic conferenceEstablished upper mediastinum lymphadenectomy in prone MIE improves outcomesPublic symposium
- 第74回日本食道学会学術集会, Japanese, 徳島大学大学院医歯薬学研究部 胸部・内分泌・腫瘍外科学分野, 徳島/Web開催, Japan, Domestic conferenceFeasibility of lymphadenectomy with thoracic duct preservation in esophageal SCCPublic symposium
- 第74回日本食道学会学術集会, Japanese, 徳島大学大学院医歯薬学研究部 胸部・内分泌・腫瘍外科学分野, 徳島/Web開催, Japan, Domestic conference表在型食道癌(pMM/SM1)に対する胸腔鏡下食道切除術の治療成績Public symposium
- 第24回バイオ治療法研究会学術集会, Japanese, 福岡大学医学部産科婦人科学講座、福岡がん総合クリニック, web開催, Japan, Domestic conference食道癌術前化学療法の効果予測因子における癌幹細胞マーカーの有用性に関する検討Oral presentation
- 第24回バイオ治療法研究会学術集会, Japanese, 福岡大学医学部産科婦人科学講座、福岡がん総合クリニック, web開催, Japan, Domestic conference腹膜播種における腹腔内MDSCの役割Oral presentation
- 第33回日本外科感染症学会総会学術集会, Japanese, 防衛医科大学校 外科学講座, web開催, Japan, Domestic conferenceNACRT 施行後腹会陰式直腸切断術における大網充填術の有用性Poster presentation
- 第33回日本外科感染症学会総会学術集会, Japanese, 防衛医科大学校 外科学講座, web開催, Japan, Domestic conference高齢者胃癌切除後の肺炎併発による長期予後への影響の検討Public symposium
- 第33回日本外科感染症学会総会学術集会, Japanese, 防衛医科大学校 外科学講座, web開催, Japan, Domestic conference直腸癌術後縫合不全は長期予後を悪化させるのか?Poster presentation
- 第31回日本消化器癌発生学会総会, Japanese, 大阪市立大学大学院医学研究科 消化器外科, web開催, Japan, Domestic conference直腸癌に対するTa-TME併用直腸切除術の手術手技と手術成績Public symposium
- 第31回日本消化器癌発生学会総会, Japanese, 大阪市立大学大学院医学研究科 消化器外科, web開催, Japan, Domestic conference鼠経リンパ節転移陽性直腸癌に対する治療戦略Oral presentation
- 第31回日本消化器癌発生学会総会, Japanese, 大阪市立大学大学院医学研究科 消化器外科, web開催, Japan, Domestic conference大腸癌腹膜播種の病勢に骨髄由来免疫抑制細胞が及ぼす影響とその治療応用Public symposium
- 第31回日本消化器癌発生学会総会, Japanese, 大阪市立大学大学院医学研究科 消化器外科, web開催, Japan, Domestic conference放射線治療は、腫瘍内CD8+T細胞の増加とサイトカイン産生を増強し、抗腫瘍効果に寄与するPublic symposium
- 第31回日本消化器癌発生学会総会, Japanese, 大阪市立大学大学院医学研究科 消化器外科, web開催, Japan, Domestic conference当院における胃・食道胃接合部腺癌に対する術前化学療法の治療成績の検討Public symposium
- 第50回胃外科・術後障害研究会, Japanese, 帝京大学医学部外科学講座, web開催, Japan, Domestic conference当科における胃癌および食道胃接合部癌に対する術前化学療法の治療成績Public symposium
- TaTME Seminar -Basic 導入編-, Japanese, ジョンソン・エンド・ジョンソン株式会社, web開催, Japan, Domestic conference総合司会Others
- JDDW2020(第28回日本消化器関連学会週間), Japanese, 一般社団法人日本消化器関連学会機構, 神戸/web開催, Japan, Domestic conference完全腹腔鏡下幽門側胃切除における点墨による胃切離線決定法の有用性Poster presentation
- JDDW2020(第28回日本消化器関連学会週間), Japanese, 一般社団法人日本消化器関連学会機構, 神戸/web開催, Japan, Domestic conferenceNACRT施行後腹会陰式直腸切断術における大網充填術の有用性Poster presentation
- JDDW2020(第28回日本消化器関連学会週間), Japanese, 一般社団法人日本消化器関連学会機構, 神戸/web開催, Japan, Domestic conference低肺機能に対する腹臥位胸腔鏡下食道切除術Poster presentation
- JDDW2020(第28回日本消化器関連学会週間), Japanese, 一般社団法人日本消化器関連学会機構, 神戸/web開催, Japan, Domestic conference食道胃接合部癌Siewert2型におけるリンパ節転移の予後への影響Poster presentation
- JDDW2020(第28回日本消化器関連学会週間), Japanese, 一般社団法人日本消化器関連学会機構, 神戸/web開催, Japan, Domestic conferenceStageⅣ胃癌に対するconversion surgeryPoster presentation
- JDDW2020(第28回日本消化器関連学会週間), Japanese, 一般社団法人日本消化器関連学会機構, 神戸/web開催, Japan, Domestic conference十二指腸乳頭に近接する表在型腫瘍に対する乳頭損傷予防として膵管ステントを用いた腫瘍切除術式の検討Poster presentation
- 第73回日本胸部外科学会定期学術集会, Japanese, 名古屋大学大学院医学系研究科 心臓外科学, web開催, Japan, Domestic conference飽和食塩溶液固定法を用いた腹臥位胸腔鏡下食道切除術のCadaver Surgical TrainingInvited oral presentation
- 第26回神戸内視鏡外科手術手技研究会, Japanese, 神戸内視鏡外科手術手技研究会、科研製薬株式会社、コヴィディエンジャパン株式会社, 神戸, Japan, Domestic conference特別講演「私と内視鏡外科手術」Public discourse
- 第79回日本癌学会学術総会, English, 広島大学大学院医系化学研究科 分子病理学, 広島, Japan, Domestic conference放射線治療は新たに浸潤するCD8+T細胞を増強し、腫瘍内CD8+T細胞の増加と抗腫瘍効果に寄与する。Poster presentation
- 第12回兵庫大腸ビデオカンファレンス, Japanese, コヴィディエンジャパン株式会社, web開催, Japan, Domestic conference情報提供Public discourse
- 第12回兵庫大腸ビデオカンファレンス, Japanese, コヴィディエンジャパン株式会社, web開催, Japan, Domestic conference総合司会Public discourse
- 第203回近畿外科学会, Japanese, 大阪市立大学大学院医学研究科 消化器外科学 乳腺・内分泌外科学, webおよび誌上開催, Japan, Domestic conferenceKillian-Jamieson 憩室内に発生した食道癌の一例Oral presentation
- 第203回近畿外科学会, Japanese, 大阪市立大学大学院医学研究科 消化器外科学 乳腺・内分泌外科学, webおよび誌上開催, Japan, Domestic conferenceTa-TME併用による腹会陰式直腸切断術の手術手技と手術成績Oral presentation
- 第33回近畿内視鏡外科研究会, Japanese, 大阪市立大学大学院 医学研究科 消化器外科学 乳腺・内分泌外科学, web開催, Japan, Domestic conference当科における下部直腸癌に対するtaTMEの手術手技と手術成績Public symposium
- 第33回近畿内視鏡外科研究会, Japanese, 大阪市立大学大学院 医学研究科 消化器外科学 乳腺・内分泌外科学, web開催, Japan, Domestic conference低肺機能食道患者に対する腹臥位胸腔鏡下食道切除術Oral presentation
- 第33回近畿内視鏡外科研究会, Japanese, 大阪市立大学大学院 医学研究科 消化器外科学 乳腺・内分泌外科学, web開催, Japan, Domestic conference腹臥位胸腔鏡下食道切除における上縦隔郭清の工夫Public symposium
- 第33回近畿内視鏡外科研究会, Japanese, 大阪市立大学大学院 医学研究科 消化器外科学 乳腺・内分泌外科学, web開催, Japanワークショップ1 腹腔鏡下右半分結腸切除時の中枢郭清のこだわりPublic symposium
- 第33回近畿内視鏡外科研究会, Japanese, 大阪市立大学大学院医学研究科 消化器外科学 乳腺・内分泌外科学, web開催, Japan, Domestic conferenceエキスパートが語る最新の手術手技~新型フレキシブルスコープを用いた腹腔鏡下手術~Public discourse
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conference食道癌手術における術前の歯牙欠損と術後の予後との関係Poster presentation
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conference胸部食道癌術後にsevereな体重減少を認める症例は予後不良であり、周術期に短期的な経腸栄養を行っても改善しないPoster presentation
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conference間葉系幹細胞由来のCXCL16は胃癌細胞においてSTAT3経路を介してRor1の発現を誘導し増殖と遊走を促進するPoster presentation
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conference食道亜全摘術の再建経路選択におけるICG蛍光観察法の有用性Poster presentation
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conferenceオープンソースの物体検出アルゴリズムを用いた腹腔鏡下胃癌手術ビデオにおける手術器具自動認識システムの開発と利用Invited oral presentation
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conference食道癌手術における術後合併症予測因子及び長期予後予測因子としてのSurgical Apgar Scoreの有用性Public symposium
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conference食道胃接合部癌 Siewert2 型におけるリンパ節転移の予後への影響Poster presentation
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conference直腸癌術後縫合不全は長期予後を悪化させるのか?Poster presentation
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conference当院における腹腔鏡下胃全摘術の安全性と有用性Poster presentation
- 第120回日本外科学会定期学術集会, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conference表在性非乳頭部十二指腸腫瘍に対する腹腔鏡内視鏡合同手術~腫瘍局在に応じた外科手技の工夫と治療成績~Public symposium
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conference術後腹膜炎が転移を促進させる-マウス腹膜炎モデルにおける肺転移への影響Public symposium
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conference「外側先行剥離」による新しいTaTME手技Public symposium
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conferenceシンポジウム(13) 「画像情報を駆使した下部消化管手術」Others
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conferenceデジタルポスター(159) 大腸 リンパ節転移・郭清Others
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conferenceロボット支援手術における上縦隔郭清手技とその可能性Public symposium
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conference食道癌に対する胸腔鏡下手術の治療成績Public symposium
- 第120回日本外科学会定期学術集会, Japanese, 慶応義塾大学医学部外科学教室, web開催, Japan, Domestic conference食道胃接合部腺癌に対する術前補助化学療法の検討Poster presentation
- 第92回日本胃癌学会総会, English, 国立がん研究センター 先端医療開発センター, web開催, Japan, Domestic conferenceConversion surgery following chemotherapy for Stage Ⅳ gastric cancerPoster presentation
- 第92回日本胃癌学会総会, English, 国立がん研究センター 先端医療開発センター, web開催, Japan, Domestic conferenceリンパ節転移を伴う早期胃癌の予後に関する検討Oral presentation
- 第92回日本胃癌学会総会, English, 国立がん研究センター 先端医療開発センター, web開催, Japan, Domestic conference抗血栓療法中患者に対する胃切除術における周術期抗血栓療法の検討Poster presentation
- 第92回日本胃癌学会総会, English, 国立がん研究センター 先端医療開発センター, web開催, Japan, Domestic conference高齢者局所進行胃癌に対する術前化学療法の有効性と安全性Oral presentation
- 第92回日本胃癌学会総会, English, 国立がん研究センター 先端医療開発センター, web開催, Japan, Domestic conferenceSiewert Ⅱ型食道胃接合部癌に対する偽His角・fornix形成食道胃管再建Poster presentation
- 第92回日本胃癌学会総会, English, 国立がん研究センター 先端医療開発センター, web開催, Japan, Domestic conference食道胃接合部腺癌に対する術前補助化学療法の有用性Oral presentation
- 第41回癌免疫外科研究会, Japanese, 大阪大学大学院医学系研究科 臨床腫瘍免疫学, 大阪, Japan, Domestic conference腹膜播種の病勢に腹腔内骨髄由来抑制細胞が及ぼす影響と、治療標的としての可能性Oral presentation
- 第41回癌免疫外科研究会, Japanese, 大阪大学大学院医学系研究科 臨床腫瘍免疫学, 大阪, Japan, Domestic conferenceNKT細胞ワクチンベクターの抗原特異的T細胞の活性化Oral presentation
- AACR Annual Meeting 2020, English, web開催, International conferenceRadiationtherapy for tumors enhances newly-infiltrating CD8⁺T cells and contributes to the increase of intratumor CD8⁺T cells and anti-tumor effects.Poster presentation
- 第3回兵庫腹腔鏡下大腸切除研究会, Japanese, ジョンソン・エンド・ジョンソン株式会社, web開催, Japan, Domestic conference閉会の辞Public discourse
- 第3回兵庫腹腔鏡下大腸切除研究会, Japanese, ジョンソン・エンド・ジョンソン株式会社, web開催, Japan, Domestic conferenceコメンテーターPublic discourse
- 日本消化器病学会近畿支部第112回例会, Japanese, 京都府立医科大学大学院医学研究科消化器内科学, 誌上開催, Japan, Domestic conference当科における鼠径リンパ節転移陽性直腸癌に治療成績Oral presentation
- 第53回制癌剤適応研究会, Japanese, 京都府立医科大学大学院医学研究科 消化器外科学, 滋賀, Japan, Domestic conference当科における鼠径リンパ節転移陽性直腸癌の治療戦略Poster presentation
- 第53回制癌剤適応研究会, Japanese, 京都府立医科大学大学院医学研究科 消化器外科学, 滋賀, Japan, Domestic conference局所進行直腸癌に対する術前化学放射線療法における治療成績の比較検討Poster presentation
- 第53回制癌剤適応研究会, Japanese, 京都府立医科大学大学院医学研究科 消化器外科学, 滋賀, Japan, Domestic conference当院における高頻度マイクロサテライト不安定性大腸癌のスクリーニング方法の検討Public symposium
- 第53回制癌剤適応研究会, Japanese, 京都府立医科大学大学院医学研究科 消化器外科学, 滋賀, Japan, Domestic conference食道扁平上皮癌術前化学療法によるPD-L1発現とCD8陽性腫瘍浸潤リンパ球の誘導Public symposium
- 神戸から発信する最新がん治療法(神戸大学医学部 市民公開講座), Japanese, 神戸大学医学部付属病院、神戸大学医学部付属病院国際がん医療・研究センター、神戸大学大学院医学研究科、神戸新聞社, 神戸, Japan, Domestic conference大腸がんの最新外科治療~患者さん一人ひとりに合わせたオーダーメイド手術~Public discourse
- 第16回日本消化管学会総会学術集会, Japanese, 名古屋市立大学大学院 医学研究科 次世代医療開発学, 姫路, Domestic conferenceG-CSF(granulicyte-colony stimulating factor)産生胎児消化管上皮類似食道癌の1例Oral presentation
- 第16回日本消化管学会総会学術集会, Japanese, 名古屋市立大学大学院 医学研究科 次世代医療開発学, 姫路, Japan, Domestic conference輸血依存の重症再生不良性貧血経過中に大腸癌術後の穿通性吻合部潰瘍を発症し周術期管理が奏効した1例Oral presentation
- 15th ANNUAL ACADEMIC SURGICAL CONGRESS, English, Academic Surgical Congress · Association for Academic Surgery · Society of University Surgeons, Florida, United States, International conferenceContribution of 3-dimensional system in advance of Minimally Invasive Esophagectomy.Oral presentation
- 15th ANNUAL ACADEMIC SURGICAL CONGRESS, English, Academic Surgical Congress · Association for Academic Surgery · Society of University Surgeons, Florida, United States, International conferenceInfluence of Lymphatic Metastasis on the Recurrence of Adenocarcinoma of the Esophagogastric JunctionOral presentation
- 第96回大腸癌研究会, Japanese, 広島大学大学院医系科学研究科 内視鏡医学, 広島, Japan, Domestic conferenceStageⅢ大腸癌術後補助化学療法の検討Oral presentation
- 第32回日本内視鏡外科学会総会, Japanese, 東海大学医学部消化器外科, 横浜, Japan, Domestic conferenceミラーイメージの克服についての工夫と検討、左右差についてOral presentation
- 第32回日本内視鏡外科学会総会, Japanese, 東海大学医学部消化器外科, 横浜, Japan, Domestic conference完全腹腔鏡下幽門側胃切除術における点墨による病変マーキングの有用性Oral presentation
- 第32回日本内視鏡外科学会総会, Japanese, 東海大学医学部消化器外科, 横浜, Japan, Domestic conferenceASA class 3,4 のhigh risk 大腸癌患者における腹腔鏡手術の有用性Oral presentation
- 第32回日本内視鏡外科学会総会, Japanese, 東海大学医学部消化器外科, 横浜, Japan, Domestic conference低肺機能に対する腹臥位胸腔鏡下食道切除術Public symposium
- 第32回日本内視鏡外科学会総会, Japanese, 東海大学医学部消化器外科, 横浜, Japan, Domestic conference腹腔鏡下噴門側胃切除後の食道胃管再建に関する検討Oral presentation
- 第32回日本内視鏡外科学会総会, Japanese, 東海大学医学部消化器外科, 横浜, Japan, Domestic conference評価型外科縫合シミュレーターを活用した研修医・専攻医に対する腹腔鏡縫合結紮トレーニングOral presentation
- 第32回日本内視鏡外科学会総会, Japanese, 東海大学医学部消化器外科, 横浜, Japan, Domestic conference吻合を用いた腹腔鏡下胃全摘の検討Oral presentation
- 第32回日本内視鏡外科学会総会, Japanese, 東海大学医学部消化器外科, 横浜, Japan, Domestic conferenceロボット支援Minimally invasive esophagectomy の可能性Public symposium
- 第32回日本内視鏡外科学会総会, Japanese, 東海大学医学部消化器外科, 横浜, Japan, Domestic conference腹腔鏡下結腸右半切除D3郭清における頭側アプローチの有用性Public symposium
- 第32回日本内視鏡外科学会総会, Japanese, 東海大学医学部消化器外科, 横浜, Japan, Domestic conference外側先行剥離によるTa-TME の標準化Public symposium
- 第32回日本内視鏡外科学会総会, Japanese, 東海大学医学部消化器外科, 横浜, Japan, Domestic conference施設内定型化郭清手技による反回神経麻痺の低減Public symposium
- 第23回バイオ治療法研究会学術集会, Japanese, 新潟薬科大学 健康・自立総合研究機構, 新潟, Japan, Domestic conferenceα-ガラクトシルセラミドを付加し、腫瘍抗原を導入した樹状細胞ワクチンベクターの抗腫瘍効果Oral presentation
- 7th FACO Academic Conference, English, Chinese Society of Clinical Oncology, Shanghai, China, International conferenceWhen should esophagectomy be performed to non-curative superficial esophageal cancer after endoscopic resection?Poster presentation
- 7th FACO Academic Conference, English, Chinese Society of Clinical Oncology, Shanghai, China, International conferenceTreatment Strategy for Rectal Cancer Patients With Inguinal Lymph Node MetastasisPoster presentation
- 7th FACO Academic Conference, English, Chinese Society of Clinical Oncology, Shanghai, China, International conferenceSafety of preoperative chemotherapy for elderly gastric cancer patientsPoster presentation
- 第28回日本コンピューター外科学会大会, Japanese, 東京大学医学部附属病院 心臓外科, 東京, Japan, Domestic conference物体検出アルゴリズムを用いた鉗子軌道解析法の開発Oral presentation
- 第30回日本消化器癌発生学会総会, Japanese, 一般社団法人 日本消化器癌発生学会, 横浜, Japan, Domestic conferenceα-ガラクトシルセラミドを付加し、 腫瘍抗原を導入した樹状細胞ワクチンベクターの抗腫瘍効果Public symposium
- 第30回日本消化器癌発生学会総会, Japanese, 一般社団法人 日本消化器癌発生学会, 横浜, Japan, Domestic conference当院における高頻度マイクロサテライト不安定性大腸癌のスクリーニング方法の検討Public symposium
- 第30回日本消化器癌発生学会総会, Japanese, 一般社団法人 日本消化器癌発生学会, 横浜, Japan, Domestic conference当科における鼠径リンパ節転移陽性直腸癌の治療戦略と成績Poster presentation
- 第30回日本消化器癌発生学会総会, Japanese, 一般社団法人 日本消化器癌発生学会, 横浜, Japan, Domestic conference食道扁平上皮癌術前化学療法によるPD-L1発現とCD8陽性腫瘍浸潤リンパ球の誘導Public symposium
- 第30回日本消化器癌発生学会総会, Japanese, 一般社団法人 日本消化器癌発生学会, 横浜, Japan, Domestic conference腹膜播種における腹腔内腫瘍免疫微小環境の解析Public symposium
- 第30回日本消化器癌発生学会総会, Japanese, 一般社団法人 日本消化器癌発生学会, 横浜, Japan, Domestic conference胸部食道癌に対し予防的頸部リンパ節郭清は省略可能かPublic symposium
- Millennial Seminar of GI Cancer, Japanese, 中外製薬株式会社, 神戸, Japan, Domestic conference特別講演1Public discourse
- 第49回胃外科・術後障害研究会, Japanese, 鹿児島大学大学院 消化器・乳腺甲状腺外科学, 鹿児島, Japan, Domestic conference高齢者の胃癌切除後における炎症に基づく予後予測スコアの有用性Public symposium
- 第49回胃外科・術後障害研究会, Japanese, 鹿児島大学大学院 消化器・乳腺甲状腺外科学, 鹿児島, Japan, Domestic conference早期胃癌に対するESD後追加外科切除例の検討Public symposium
- 第49回胃外科・術後障害研究会, Japanese, 鹿児島大学大学院 消化器・乳腺甲状腺外科学, 鹿児島, Japan, Domestic conference食道胃接合部に近接するGISTに対する噴門機能を温存した腹腔鏡下局所切除の安全性に関する検討Public symposium
- 第57回日本癌治療学会学術集会, Japanese, 岐阜大学大学院医学系研究科 脳腫瘍制御学講座 腫瘍外科学分野, 福岡, Japan, Domestic conference歯牙欠損は食道癌術後の予後を悪化させるOral presentation
- 第57回日本癌治療学会学術集会, Japanese, 岐阜大学大学院医学系研究科 脳腫瘍制御学講座 腫瘍外科学分野, 福岡, Japan, Domestic conference食道扁平上皮癌術前化学療法によるPD-L1発現とCD8陽性腫瘍浸潤リンパ球の誘導Oral presentation
- 第57回日本癌治療学会学術集会, Japanese, 岐阜大学大学院医学系研究科 脳腫瘍制御学講座 腫瘍外科学分野, 福岡, Japan, Domestic conference下部進行直腸癌に対する術前化学放射線療法と選択的側方郭清の治療成績Public symposium
- 第57回日本癌治療学会学術集会, Japanese, 岐阜大学大学院医学系研究科 脳腫瘍制御学講座 腫瘍外科学分野, 福岡, Japan, Domestic conference局所進行胃癌に対するneoadjuvant cheterapyとしてのSOX療法の安全性Poster presentation
- 第57回日本癌治療学会学術集会, Japanese, 岐阜大学大学院医学系研究科 脳腫瘍制御学講座 腫瘍外科学分野, 福岡, Japan, Domestic conference抗血栓薬内服患者に対する胃切除術における周術期抗血栓療法の検討Public symposium
- 第57回日本癌治療学会学術集会, Japanese, 岐阜大学大学院医学系研究科 脳腫瘍制御学講座 腫瘍外科学分野, 福岡, Japan, Domestic conference食道癌手術治療に対するエノキサパリンによる静脈血栓塞栓症予防Poster presentation
- 第57回日本癌治療学会学術集会, Japanese, 岐阜大学大学院医学系研究科 脳腫瘍制御学講座 腫瘍外科学分野, 福岡, Japan, Domestic conference鼠径リンパ節転移を伴う直腸癌に対する術前化学放射線療法Oral presentation
- 第57回日本癌治療学会学術集会, Japanese, 岐阜大学大学院医学系研究科 脳腫瘍制御学講座 腫瘍外科学分野, 福岡, Japan, Domestic conferenceStageIV 胃癌に対するconversion surgeryの検討Oral presentation
- 第57回日本癌治療学会学術集会, Japanese, 岐阜大学大学院医学系研究科 脳腫瘍制御学講座 腫瘍外科学分野, 福岡, Japan, Domestic conference内視鏡治療後非治癒切除症例に対する食道切除術の意義と適応Public symposium
- 第27回近畿内視鏡下大腸手術研究会, Japanese, 近畿内視鏡下大腸手術研究会、株式会社ツムラ、ジョンソンエンド・ジョンソン株式会社、大鵬薬品工業株式会社, 京都, Japan, Domestic conference特別講演III 直腸癌におけるもう一つの選択肢〜TaTME〜Others
- 日本消化器病学会近畿支部第111回例会, Japanese, 神戸大学大学院医学研究科外科学講座食道胃腸外科学, 大阪, Japan, Domestic conference腹腔鏡下に切除し得た副腎腫瘤を合併した家族性大腸ポリポーシスの1例Oral presentation
- 日本消化器病学会近畿支部第111回例会, Japanese, 神戸大学大学院医学研究科外科学講座食道胃腸外科学, 大阪, Japan, Domestic conference胸腔鏡下核出術を施行した食道神経鞘腫の一例Oral presentation
- 日本消化器病学会近畿支部第111回例会, Japanese, 神戸大学大学院医学研究科外科学講座食道胃腸外科学, 大阪, Japan, Domestic conference術前化学療法中にG-CSF(granulocyte-colony stimulating factor)産生腫瘍の診断を得た進行食道腺癌Oral presentation
- 日本消化器病学会近畿支部第111回例会, Japanese, 神戸大学大学院医学研究科外科学講座食道胃腸外科学, 大阪, Japan, Domestic conference外側先行剥離による安全なTa-TME手技の確立Public symposium
- 第202回近畿外科学会, Japanese, 大阪大学大学院医学系研究科 外科学講座 消化器外科学, 大阪, Japan, Domestic conference完全内臓逆位を伴うS状結腸癌に対して腹腔鏡下S状結腸切除を施行した一例Oral presentation
- 第202回近畿外科学会, Japanese, 大阪大学大学院医学系研究科 外科学講座 消化器外科学, 大阪, Japan, Domestic conference炎症による反復性幽門狭窄をきたした胃異所性膵に対して腹腔鏡下幽門側胃切除術を行った1例Oral presentation
- 第202回近畿外科学会, Japanese, 大阪大学大学院医学系研究科 外科学講座 消化器外科学, 大阪, Japan, Domestic conference後縦隔経路再建胃管癌に対する腹臥位胸腔鏡下胃管全摘術の2例Oral presentation
- 第202回近畿外科学会, Japanese, 大阪大学大学院医学系研究科 外科学講座 消化器外科学, 大阪, Japan, Domestic conference鼠径リンパ節転移陽性直腸癌に対する治療戦略Oral presentation
- 第202回近畿外科学会, Japanese, 大阪大学大学院医学系研究科 外科学講座 消化器外科学, 大阪, Japan, Domestic conference大動脈十二指腸瘻の治療経験Oral presentation
- 第32回近畿内視鏡外科研究会, Japanese, 大阪大学大学院医学系研究科 産科学婦人科学教室, 大阪, Japan, Domestic conference頭側アプローチによる腹腔鏡下右半結腸切除Public symposium
- 第32回近畿内視鏡外科研究会, Japanese, 大阪大学大学院医学系研究科 産科学婦人科学教室, 大阪, Japan, Domestic conference腹臥位胸腔鏡下食道切除における上縦隔郭清の定形化Public symposium
- 第32回近畿内視鏡外科研究会, Japanese, 大阪大学大学院医学系研究科 産科学婦人科学教室, 大阪, Japan, Domestic conferenceワークショップ11Others
- 第29回兵庫腹腔鏡外科勉強会, Japanese, 兵庫腹腔鏡外科勉強会、ジョンソン・エンド・ジョンソン株式会社, 神戸, Japan, Domestic conference当科における株式会社直腸癌手術の治療成績 ta-TME vs.lap-TMEPublic discourse
- 第28回消化器疾患病態治療研究会, Japanese, 愛知医科大学 消化管内科, 名古屋, Japan, Domestic conference胃管癌に対する低侵襲治療Oral presentation
- 第28回消化器疾患病態治療研究会, Japanese, 愛知医科大学 消化管内科, 名古屋, Japan, Domestic conference当院における胃SMT に対する腹腔鏡手術に関する検討Oral presentation
- 日本・モンゴル国際消化器がんシンポジウム, English, Ulaanbaatar, Mongolia, International conferenceSafety and effectiveness of laparoscopic colorectomy for elderly patients: A propensity-score matching analysisOral presentation
- 日本・モンゴル国際消化器がんシンポジウム, English, Ulaanbaatar, Mongolia, International conferenceTransanal total mesorectal excision for rectal cancer by two-surgeon teamOral presentation
- 日本・モンゴル国際消化器がんシンポジウム, English, Ulaanbaatar, Mongolia, International conferenceLaparoscopic surgery for gastric GISTOral presentation
- 第74回日本消化器外科学会総会, Japanese, 東京慈恵会医科大学, 東京, Japan, Domestic conference胃管癌に対する胸腔鏡手術の導入Public symposium
- 第74回日本消化器外科学会総会, Japanese, 東京慈恵会医科大学, 東京, Japan, Domestic conference胸部食道癌に対し予防的頸部リンパ節郭清は全例に必要か;予防的頸部郭清省略の検討Public symposium
- 第74回日本消化器外科学会総会, Japanese, 東京慈恵会医科大学, 東京, Japan, Domestic conference食道癌に対する胸腔鏡下食道切除術、propensity scoreを用いた腹臥位と左側臥位の予後の比較Poster presentation
- 第74回日本消化器外科学会総会, Japanese, 東京慈恵会医科大学, 東京, Japan, Domestic conference胸壁前有茎空腸再建術の工夫と有用性Oral presentation
- 第74回日本消化器外科学会総会, Japanese, 東京慈恵会医科大学, 東京, Japan, Domestic conference腹腔鏡下噴門即胃切除後の食道胃管再建に関する検討Poster presentation
- 第74回日本消化器外科学会総会, Japanese, 東京慈恵会医科大学, 東京, Japan, Domestic conference胃癌に対する腹腔鏡下脾動脈近位側郭清における画像によるシミュレーションと左外側アプローチの有用性Oral presentation
- 第74回日本消化器外科学会総会, Japanese, 東京慈恵会医科大学, 東京, Japan, Domestic conference当科で術前化学療法を施行した腎機能障害を有する胃癌症例の検討Poster presentation
- 第74回日本消化器外科学会総会, Japanese, 東京慈恵会医科大学, 東京, Japan, Domestic conferenceαガラクトシルセラミド付加した抗原導入した樹状細胞抗腫瘍ベクターの抗腫瘍効果Public symposium
- 第74回日本消化器外科学会総会, Japanese, 東京慈恵会医科大学, 東京, Japan, Domestic conference進行横行結腸癌に対する発生解剖に基づいた鏡視下手術:頭側アプローチのコツと工夫Oral presentation
- 第74回日本消化器外科学会総会, Japanese, 東京慈恵会医科大学, 東京, Japan, Domestic conference消化器外科医に求められる大動脈食道瘻の手術治療戦略Oral presentation
- 第74回日本消化器外科学会総会, Japanese, 東京慈恵会医科大学, 東京, Japan, Domestic conference慢性腎臓病(CKD)の胃癌切除後の合併症発生に及ぼす影響Public symposium
- 第91回大腸癌研究会, Japanese, がん・感染症センター 都立駒込病院 外科, 東京, Japan, Domestic conference当院における大腸NETの手術治療成績Poster presentation
- 第26回外科侵襲とサイトカイン研究会, Japanese, 神戸大学大学院医学研究科外科系講座 災害・救急医学分野, 神戸, Japan, Domestic conference術後腹膜炎が肺転移の予後に及ぼす影響とその免疫学的検討Public symposium
- 2019大腸手術手技勉強会-Video CAMPS, Japanese, コヴィディエンジャパン株式会社, 名古屋, Japan, Domestic conference第2部 特別講演Invited oral presentation
- 2019大腸手術手技勉強会-Video CAMPS, Japanese, コヴィディエンジャパン株式会社, 名古屋, Japan, Domestic conference第1部 Video ConfarenceOthers
- 第28回日本癌病態治療研究会, Japanese, 埼玉医科大学総合医療センター 消化管・一般外科/ゲノム診療科, 川越, Japan, Domestic conference直腸癌手術における術中内視鏡検査による吻合部評価の有用性Poster presentation
- 第28回日本癌病態治療研究会, Japanese, 埼玉医科大学総合医療センター 消化管・一般外科/ゲノム診療科, 川越, Japan, Domestic conference食道癌における術前化学療法症例による免疫微小環境の変化Public symposium
- 第28回日本癌病態治療研究会, Japanese, 埼玉医科大学総合医療センター 消化管・一般外科/ゲノム診療科, 川越, Japan, Domestic conference胸部食道癌に対し予防的頸部リンパ節郭清は全例に必要かPublic symposium
- 第44回日本外科系連合学会学術集会, Japanese, 金沢医科大学 一般・消化器外科学, 金沢, Japan, Domestic conference3Dモニターが手術操作にもたらす影響に関する術者技術レベルごとの検討Public symposium
- 第44回日本外科系連合学会学術集会, Japanese, 金沢医科大学 一般・消化器外科学, 金沢, Japan, Domestic conference術前化学療法として SOX 療法を施行した進行食道胃接合部癌の 4 例Oral presentation
- 第44回日本外科系連合学会学術集会, Japanese, 金沢医科大学 一般・消化器外科学, 金沢, Japan, Domestic conference女性外科医から始める働き方改革Public symposium
- 第44回日本外科系連合学会学術集会, Japanese, 金沢医科大学 一般・消化器外科学, 金沢, Japan, Domestic conference高齢者の胃癌切除におけるCONUT scoreによるフレイル判定の有用性Public symposium
- 第44回日本外科系連合学会学術集会, Japanese, 金沢医科大学 一般・消化器外科学, 金沢, Japan, Domestic conference3ステップ法による腹腔鏡下結腸脾弯曲授動Public symposium
- 第44回日本外科系連合学会学術集会, Japanese, 金沢医科大学 一般・消化器外科学, 金沢, Japan, Domestic conference胸腔鏡下食道癌手術におけるエノキサパリンによる静脈血栓塞栓症予防Oral presentation
- 第41回日本癌局所療法研究会, Japanese, 川崎医科大学臨床腫瘍学, 岡山, Japan, Domestic conference虫垂腺癌術後の吻合部再発と診断され、神経内分泌癌と診断された1手術例Oral presentation
- 第41回日本癌局所療法研究会, Japanese, 川崎医科大学臨床腫瘍学, 岡山, Japan, Domestic conference高齢者の胃癌切除症例における術前末梢血中リンパ球数の臨床的意義Oral presentation
- 27th European Association for Endoscopic Surgery (EAES2019), English, Seville, Spain, International conferenceA new technique for lymph node dissection along proximal splenic artery during laparoscopic gastrectomy for gastric cancer: Left-lateral approach.Public symposium
- 第73回日本食道学会学術集会, Japanese, 独立行政法人国立病院機構 九州がんセンター, 福岡, Japan, Domestic conference高齢食道癌患者に対する胸腔鏡手術の妥当性Poster presentation
- 第73回日本食道学会学術集会, Japanese, 独立行政法人国立病院機構 九州がんセンター, 福岡, Japan, Domestic conferenceロボット支援下食道切除術の導入と初期治療成績Poster presentation
- 第73回日本食道学会学術集会, Japanese, 独立行政法人国立病院機構 九州がんセンター, 福岡, Japan, Domestic conference食道癌に対する胸腔鏡下食道切除術、腹臥位と左側臥位の予後の比較Poster presentation
- 第73回日本食道学会学術集会, Japanese, 独立行政法人国立病院機構 九州がんセンター, 福岡, Japan, Domestic conference当科での腹臥位胸腔鏡下食道切除術における上縦隔郭清手技と成績Poster presentation
- 第23回神戸内視鏡外科手術手技研究会, Japanese, 神戸内視鏡外科手術手技研究会、科研製薬株式会社、コヴィディエンジャパン株式会社, 神戸, Japan, Domestic conference特別講演 下部直腸癌に対する内視鏡外科治療Others
- 第29回日本サイトメトリー学会学術集会, Japanese, 順天堂大学医学部内科学血液学講座, 東京, Japan, Domestic conferenceαガラクトシルセラミド付加した抗原導入した樹状細胞ベクターの抗腫瘍効果Oral presentation
- 第29回日本サイトメトリー学会学術集会, Japanese, 順天堂大学医学部内科学血液学講座, 東京, Japan, Domestic conference腹膜播種マウスモデルにおける腹腔内骨髄由来抑制細胞(MDSC)の検討Oral presentation
- 第73回手術手技研究会, Japanese, 上尾中央総合病院 外科, 東京, Japan, Domestic conferenceTa-TME における「外側先行剥離」による安全な手術手技Public symposium
- 第40回癌免疫外科研究会, Japanese, 金沢大学 消化器・腫瘍・再生外科学, 金沢, Japan, Domestic conference消化器癌患者の末梢血T細胞におけるimmunological synapseの評価Public symposium
- 第40回癌免疫外科研究会, Japanese, 金沢大学 消化器・腫瘍・再生外科学, 金沢, Japan, Domestic conference直腸癌術前化学放射線療法における腫瘍免疫因子の発現動態の解析Public symposium
- 第40回癌免疫外科研究会, Japanese, 金沢大学 消化器・腫瘍・再生外科学, 金沢, Japan, Domestic conferenceタンパク抗原を導入したNKT細胞活性化樹状細胞ワクチンベクターの抗腫瘍効果Oral presentation
- IGCC 2019 第13回国際胃癌学会議, English, Prague, Czech Republic, International conferencePrediction of the dorsal landmark using 3D-CT during laparoscopic lymph node dissection along the proximal splenic artery in gastric cancerPoster presentation
- 第44回 KSELS & 国際シンポジウム, English, The Korean Society of Endoscopic & Laparoscopic Surgeons, Seoul, Korea, Republic of, International conferenceRoutine Placement of Feeding Jejunostomy Tube during Thoracoscopic Esophagectomy Increases Postoperative Complications and Does Not Improve Postoperative MalnutritionPoster presentation
- 第119回日本外科学会定期学術集会, Japanese, 一般社団法人日本外科学会, 大阪, Japan, Domestic conference胸部食道癌手術において経腸栄養tube は全例に必要か?Poster presentation
- 第119回日本外科学会定期学術集会, Japanese, 一般社団法人日本外科学会, 大阪, Japan, Domestic conferenceミラーイメージの克服についての工夫 モニターの位置とカメラの角度についての検討Poster presentation
- 第119回日本外科学会定期学術集会, Japanese, 一般社団法人日本外科学会, 大阪, Japan, Domestic conference局所進行直腸癌に対する術前化学放射線療法と画像診断に基づく選択的側方郭清の治療Poster presentation
- 第119回日本外科学会定期学術集会, Japanese, 一般社団法人日本外科学会, 大阪, Japan, Domestic conference局所進行胃癌に対する術前化学療法におけるSOX 療法の安全性と有効性Poster presentation
- 第119回日本外科学会定期学術集会, Japanese, 一般社団法人日本外科学会, 大阪, Japan, Domestic conference肺への浸潤を伴う食道癌に対する胸腔鏡下食道切除術の試みPoster presentation
- 第119回日本外科学会定期学術集会, Japanese, 一般社団法人日本外科学会, 大阪, Japan, Domestic conference腹腔鏡下胃切除術における術後大腰筋断面積変化の検討Public symposium
- 第119回日本外科学会定期学術集会, Japanese, 一般社団法人日本外科学会, 大阪, Japan, Domestic conferenceTa-TMEにおける安全な神経血管束温存と直腸尿道筋切離のための工夫Public symposium
- 第119回日本外科学会定期学術集会, Japanese, 一般社団法人日本外科学会, 大阪, Japan, Domestic conference高齢者胃癌後の肺炎併発による長期予後への影響の検討Public symposium
- 第119回日本外科学会定期学術集会, Japanese, 一般社団法人日本外科学会, 大阪, Japan, Domestic conference3D-CTを用いた脾動脈幹近位リンパ節背側境界の術前シミュレーションの有用性Public symposium
- 第119回日本外科学会定期学術集会, Japanese, 一般社団法人日本外科学会, 大阪, Japan, Domestic conference十二指腸腫瘍に対する腹腔鏡内視鏡合同手術の安全性に関する検討Public symposium
- 第119回日本外科学会定期学術集会, Japanese, 一般社団法人日本外科学会, 大阪, Japan, Domestic conference直腸癌術前化学放射線療法の免疫微小環境の変化とその予後因子の検討Public symposium
- 第119回日本外科学会定期学術集会, Japanese, 一般社団法人日本外科学会, 大阪, Japan, Domestic conferenceポスターセッション(96) 直腸-鏡視下手術-2Others
- 第31回兵庫大腸癌治療研究会, Japanese, 兵庫大腸癌治療研究会、ミヤリサン製薬株式会社、大鵬薬品株式会社, 神戸, Japan, Domestic conference術前化学放射線療法後に切除し得た直腸癌術後骨盤内再発の1例Oral presentation
- 第91回日本胃癌学会総会, Japanese, 静岡県立静岡がんセンター 胃外科, 静岡, Japan, Domestic conference術前化学療法を行った進行胃癌症例での再発例の検討Poster presentation
- 第91回日本胃癌学会総会, Japanese, 静岡県立静岡がんセンター 胃外科, 静岡, Japan, Domestic conferenceSiewertⅡ型食道胃接合部癌に対する偽His角・Fornix形成食道胃管再建Poster presentation
- 第52回制癌剤適応研究会, Mar. 2019, Japanese, 神戸大学大学院医学研究科外科学講座食道胃腸外科学分野, 神戸, Domestic conference免疫チェックポイント阻害薬の適用からみたマイクロサテライト不安定性検査の在り方Public symposium
- 第52回制癌剤適応研究会, Mar. 2019, Japanese, 神戸大学大学院医学研究科外科学講座食道胃腸外科学分野, 神戸, Domestic conference腹膜播種マウスモデルにおける腹腔内骨髄由来抑制細胞(MDSC)の検討Oral presentation
- 第52回制癌剤適応研究会, Mar. 2019, Japanese, 神戸大学大学院医学研究科外科学講座食道胃腸外科学分野, 神戸, Domestic conference直腸癌術前化学放射線療法の腫瘍免疫因子の発現動態の解析Oral presentation
- 第52回制癌剤適応研究会, Mar. 2019, Japanese, 神戸大学大学院医学研究科外科学講座食道胃腸外科学分野, 神戸, Domestic conference高齢進行胃癌患者における術前化学療法の安全性Oral presentation
- 第9回兵庫大腸ビデオカンファレンス, Mar. 2019, Japanese, コヴィディエンジャパン株式会社, 神戸, Domestic conference基調講演/ビデオカンファレンス(司会)Others
- 第52回制癌剤適応研究会, Mar. 2019, Japanese, 神戸大学大学院医学研究科外科学講座食道胃腸外科学分野, 神戸, Domestic conferenceSOX2 陰性食道扁平上皮癌はSOX2 プロモーター領域のメチル化を伴う高悪性組織亜型であるOral presentation
- 兵庫腹膣鏡下大腸切除研究会~腹膣鏡下S状結腸切除の定型化を目指して~, Feb. 2019, Japanese, ジョンソン エンド ジョンソン株式会社, 神戸, Domestic conference閉会の辞Others
- 兵庫腹膣鏡下大腸切除研究会~腹膣鏡下S状結腸切除の定型化を目指して~, Feb. 2019, Japanese, ジョンソン エンド ジョンソン株式会社, 神戸, Domestic conference症例提示①関西労災病院 症例提示②加古川中央市民病院Others
- 14TH ANNUAL ACADEMIC SURGICAL CONGRESS, Feb. 2019, English, Academic Surgical Congress · Association for Academic Surgery · Society of University Surgeons, ヒューストン, International conferenceSuperiority of esophageal reconstruction by pedicled jejunal flap with microvascular augmentation.Oral presentation
- 14TH ANNUAL ACADEMIC SURGICAL CONGRESS, Feb. 2019, English, Academic Surgical Congress · Association for Academic Surgery · Society of University Surgeons, ヒューストン, International conferenceSkeletal muscle loss in laparoscopic gastrectomy: differences between laparoscopic procedures.Oral presentation
- 第22回バイオ治療法研究会, Dec. 2018, Japanese, 特定非営利活動法人環瀬戸内自然免疫ネットワーク, 東京, Domestic conference末梢T細胞のIS形成能の測定法の確立Oral presentation
- 第31回日本内視鏡外科学会総会, Dec. 2018, Japanese, 一般社団法人日本内視鏡外科学会, 福岡, Domestic conference腹腔鏡下胃切除症例における周術期抗血栓療法の安全性の検討Oral presentation
- 第31回日本内視鏡外科学会総会, Dec. 2018, Japanese, 一般社団法人日本内視鏡外科学会, 福岡, Domestic conference腹腔鏡下胃癌手術における術前CTを用いた難易度予測Oral presentation
- 第31回日本内視鏡外科学会総会, Dec. 2018, Japanese, 一般社団法人日本内視鏡外科学会, 福岡, Domestic conference腹臥位食道癌手術における気管分岐部郭清Oral presentation
- 第31回日本内視鏡外科学会総会, Dec. 2018, Japanese, 一般社団法人日本内視鏡外科学会, 福岡, Domestic conference腹臥位胸腔鏡下食道亜全摘術において食道・気管の位置関係が左上縦隔郭清手技に及ぼす影響Oral presentation
- 第31回日本内視鏡外科学会総会, Dec. 2018, Japanese, 一般社団法人日本内視鏡外科学会, 福岡, Domestic conference当科における十二指腸腫瘍に対する腹腔鏡内視鏡合同手術Public symposium
- Millennaial Seminar of GI Cancer, Dec. 2018, Japanese, 中外製薬株式会社, 神戸, Domestic conference鼠径リンパ説転移陽性直腸患者に対する集学的治療の取り組み(座長)Others
- 第31回日本内視鏡外科学会総会, Dec. 2018, Japanese, 一般社団法人日本内視鏡外科学会, 福岡, Domestic conference食道切除・胸骨後再建後の胃管癌に対して胸腔鏡下に胃管切除術を施行した1例Oral presentation
- 第22回バイオ治療法研究会, Dec. 2018, Japanese, 特定非営利活動法人環瀬戸内自然免疫ネットワーク, 東京, Domestic conference消化器癌における術前療法による癌免疫微小環境の変化Oral presentation
- 第31回日本内視鏡外科学会総会, Dec. 2018, Japanese, 一般社団法人日本内視鏡外科学会, 福岡, Domestic conference胸腔鏡下食道切除術に対する3D内視鏡の導入は術後合併症を減少させるか?Oral presentation
- 第31回日本内視鏡外科学会総会, Dec. 2018, Japanese, 一般社団法人日本内視鏡外科学会, 福岡, Domestic conference基礎および臨床データが示す腹腔鏡下胃全摘術における3D内視鏡システムの有用性Oral presentation
- 第31回日本内視鏡外科学会総会, Dec. 2018, Japanese, 一般社団法人日本内視鏡外科学会, 福岡, Domestic conference安全なTa-TMEの確立を目指して~当科の手術成績と工夫~Oral presentation
- 第22回バイオ治療法研究会, Dec. 2018, Japanese, 特定非営利活動法人環瀬戸内自然免疫ネットワーク, 東京, Domestic conferenceマウス腹膜播種モデルにおける腹腔内骨髄由来免疫抑制細胞(MDSC)の推移Oral presentation
- 第31回日本内視鏡外科学会総会, Dec. 2018, Japanese, 一般社団法人日本内視鏡外科学会, 福岡, Domestic conferenceデジタルポスター18 胃・十二指腸良性1(司会)Others
- 第29回日本消化器癌発生学会総会, Nov. 2018, Japanese, 一般社団法人日本消化器癌発生学会, 東京, Domestic conference腹膜播種モデルにおける腹腔内骨骨髄由来抑制細胞(MDSC)の推移Oral presentation
- 第27回日本コンピューター外科学会大会, Nov. 2018, Japanese, 一般社団法人日本コンピューター外科学会, 奈良, Domestic conference内視鏡手術による技術レベルごとの3D画像の影響Others
- 第29回日本消化器癌発生学会総会, Nov. 2018, Japanese, 一般社団法人日本消化器癌発生学会, 東京, Domestic conference食道癌患者におけるT細胞表面分子集簇による機能評価Poster presentation
- 第25回近畿内視鏡下大腸手術研究会, Oct. 2018, Japanese, 近畿内視鏡下大腸手術研究会/ジョンソンエンドジョンソン株式会社, 神戸, Domestic conference特別講演Ⅰ 最新の近赤外光を用いた腹腔鏡下大腸癌手術(座長)Others
- 第56回日本癌治療学会学術集会, Oct. 2018, Japanese, 一般社団法人 日本癌治療学会, 横浜, Domestic conference高齢者胃癌の外科治療Oral presentation
- Chugai Colorectal Cancer Symposium in HYOGO, Oct. 2018, Japanese, 中外製薬株式会社, 神戸, Domestic conference患者さんの生活スタイル・嗜好を取り入れた治療選択(司会)Oral presentation
- 第25回近畿内視鏡下大腸手術研究会, Oct. 2018, Japanese, 近畿内視鏡下大腸手術研究会/ジョンソンエンドジョンソン株式会社, 神戸, Domestic conference開会の辞Others
- 第56回日本癌治療学会学術集会, Oct. 2018, Japanese, 一般社団法人 日本癌治療学会, 横浜, Domestic conference化学療法後に胃切除術を行った進行胃癌症例における予後因子の検討Poster presentation
- 第31回近畿内視鏡外科研究会, Sep. 2018, Japanese, 近畿内視鏡外科研究会, 神戸, Domestic conference腹臥位胸腔鏡下食道切除術における縦隔郭清の工夫と定型化Public symposium
- 第11回神戸消化器癌勉強会, Sep. 2018, Japanese, 株式会社ヤクルト本社, 神戸, Domestic conference当科における直腸癌治療:術前治療から側方郭清、ta-TMEまでPublic discourse
- 第31回近畿内視鏡外科研究会, Sep. 2018, Japanese, 近畿内視鏡外科研究会, 神戸, Domestic conference当科におけるTa-TMEの導入と定型化Public symposium
- 第77回日本癌学会学術総会, Sep. 2018, Japanese, 日本癌学会, 大阪, Domestic conference直腸癌術前化学放射線療法によるCD8+T細胞とPD-L1陽性免疫細胞の誘導Oral presentation
- 日本消化器病学会近畿支部第109回例会, Sep. 2018, Japanese, 日本消化器病学会, 大阪, Domestic conference食道閉塞をきたし早期手術をおこなった酸性洗剤飲用による腐食性食道炎の一例Oral presentation
- 第31回近畿内視鏡外科研究会, Sep. 2018, Japanese, 近畿内視鏡外科研究会, 神戸, Domestic conference食道切除・胸骨後再建後の胃管癌に対して胸腔鏡下に胃管切除術を施行した1例Oral presentation
- 第31回近畿内視鏡外科研究会, Sep. 2018, Japanese, 近畿内視鏡外科研究会, 神戸, Domestic conference一般演題7 大腸・小腸①(座長)Others
- 第77回日本癌学会学術総会, Sep. 2018, Japanese, 日本癌学会, 大阪, Domestic conferenceT細胞刺激後免疫シナプス様表面分子の集簇反応の評価Poster presentation
- The international society for Diseases of the Esophagus (ISDE), Sep. 2018, English, International Society for Diseases of the Esophagus, Vienna, International conferenceStagedPedicled Jejunal after Aortoesophagectomy for Aortoesophageal Fistula.Poster presentation
- The international society for Diseases of the Esophagus (ISDE), Sep. 2018, English, International Society for Diseases of the Esophagus, Vienna, International conferenceReliable Surgical Techniques for Lymphadenectomy along the Left Recurrent Laryngeal Nerve during Thoracoscipic Esophagectomy Iin the Prone Position.Others
- The international society for Diseases of the Esophagus (ISDE), Sep. 2018, English, International Society for Diseases of the Esophagus, Vienna, International conferencePseudodiverticulosis-Related Esophageal Mass with Intense Fdg UptakePoster presentation
- The international society for Diseases of the Esophagus (ISDE), Sep. 2018, English, International Society for Diseases of the Esophagus, Vienna, International conferenceComparison of the clinical outcomes of esophagectomy and chemoradiotherapy after noncurative endoscopic submucosal dissection for esophageal squamous cell carcinomaOral presentation
- The international society for Diseases of the Esophagus (ISDE), Sep. 2018, English, International Society for Diseases of the Esophagus, Vienna, International conferenceClinical Impact of Surgical Apgar Score in Predicting Postoperative Complications and Long-Term Prognosis after Esophagectomy.Poster presentation
- 地域医療連携を考える会, Aug. 2018, Japanese, 第一三共株式会社, 神戸, Domestic conference当科における下部直腸癌に対する肛門温存手術の取り組みPublic discourse
- 第22回日本がん免疫学会総会, Aug. 2018, Japanese, 日本がん免疫学会, 岡山, Domestic conference消化器癌患者におけるT細胞の刺激応答性の評価方法の検討Poster presentation
- 第73回日本消化器外科学会総会, Jul. 2018, Japanese, 一般社団法人 日本消化器外科学会, 鹿児島, Domestic conference閉塞性大腸癌に対する術前大腸ステント留置の有用性の検討Others
- 第73回日本消化器外科学会総会, Jul. 2018, Japanese, 一般社団法人 日本消化器外科学会, 鹿児島, Domestic conference腹腔鏡下側方リンパ節郭清を安全に行うための2つの筋膜を意識した手術手技Poster presentation
- 第73回日本消化器外科学会総会, Jul. 2018, Japanese, 一般社団法人 日本消化器外科学会, 鹿児島, Domestic conference腹腔鏡下胃全摘術におけるOverlap法の工夫と検討Poster presentation
- 第73回日本消化器外科学会総会, Jul. 2018, Japanese, 一般社団法人 日本消化器外科学会, 鹿児島, Domestic conference腹臥位胸腔鏡下食道切除術のlearning curveが術後合併症に及ぼす影響と今後の展望Poster presentation
- 第73回日本消化器外科学会総会, Jul. 2018, Japanese, 一般社団法人 日本消化器外科学会, 鹿児島, Domestic conference当院における腹腔鏡下胃全摘術についての検討Poster presentation
- 第73回日本消化器外科学会総会, Jul. 2018, Japanese, 一般社団法人 日本消化器外科学会, 鹿児島, Domestic conference男性直腸癌Hartmann術後人工肛門閉鎖(再吻合)において術中内視鏡を活用し腹腔鏡手術を行った1例Poster presentation
- 第73回日本消化器外科学会総会, Jul. 2018, Japanese, 一般社団法人 日本消化器外科学会, 鹿児島, Domestic conference切除可能進行胃癌における術前補助化学療法の予後因子の検討Poster presentation
- 第73回日本消化器外科学会総会, Jul. 2018, Japanese, 一般社団法人 日本消化器外科学会, 鹿児島, Domestic conference術前抗血栓療法中の胃切除患者に対する周術期抗血栓療法の検討Poster presentation
- 第27回日本がん転移学会学術集会・総会, Jul. 2018, Japanese, 日本がん転移学会, 横浜, Domestic conference術後腹膜炎が肺転移の予後に及ぼす影響とその免疫学的検討Public symposium
- 日本外科代謝栄養学会第55回学術集会, Jul. 2018, Japanese, 日本外科代謝栄養学会, 大阪, Domestic conference高齢者の胃癌治癒切除後の予後予測におけるCONUT scoreの有用性Oral presentation
- 日本外科代謝栄養学会第55回学術集会, Jul. 2018, Japanese, 日本外科代謝栄養学会, 大阪, Domestic conference高齢者における術前化学療法の安全性と栄養評価Oral presentation
- 第73回日本消化器外科学会総会, Jul. 2018, Japanese, 一般社団法人 日本消化器外科学会, 鹿児島, Domestic conference後期高齢者進行胃癌患者に対する術前化学療法の安全性Poster presentation
- 第73回日本消化器外科学会総会, Jul. 2018, Japanese, 一般社団法人 日本消化器外科学会, 鹿児島, Domestic conference胸部食道癌手術において経腸栄養tube留置は省略できるか?Poster presentation
- 第8回兵庫大腸ビデオカンファレンス, Jul. 2018, Japanese, コヴィディエンジャパン株式会社, 神戸, Domestic conference基調講演/ビデオカンファレンス(司会)Others
- 第73回日本消化器外科学会総会, Jul. 2018, Japanese, 一般社団法人 日本消化器外科学会, 鹿児島, Domestic conference胃癌術後の合併症発生の予測因子としてのeGFRの有用性Poster presentation
- 第73回日本消化器外科学会総会, Jul. 2018, Japanese, 一般社団法人 日本消化器外科学会, 鹿児島, Domestic conferencepT4b症例における腹腔鏡手術の治療成績Others
- 第73回日本消化器外科学会総会, Jul. 2018, Japanese, 一般社団法人 日本消化器外科学会, 鹿児島, Domestic conferenceKM-CARTにより原発性胆汁性胆管炎による難治性腹水の減少を認めた1例Poster presentation
- 第89回大腸癌研究会, Jul. 2018, Japanese, 大腸癌研究会, 新潟, Domestic conferencecT1大腸癌におけるESD穿孔症例の検討Poster presentation
- 第43回日本外科系連合学会学術集会, Jun. 2018, Japanese, 一般社団法人 学会支援機構内日本外科系連合学会事務局, 東京, Domestic conference鼠径リンパ節転移を伴う進行直腸癌に対する術前化学放射線療法と手術の制御効果Oral presentation
- 第43回日本外科系連合学会学術集会, Jun. 2018, Japanese, 一般社団法人 学会支援機構内日本外科系連合学会事務局, 東京, Domestic conference高齢者胃癌患者における術後肺炎併発の長期予後への影響Public symposium
- 第72回日本食道学会学術集会, Jun. 2018, Japanese, 特定非営利活動法人 日本食道学会, 宇都宮, Domestic conference胸部食道癌手術において経腸栄養tubeは全例に必要か?Poster presentation
- 第72回日本食道学会学術集会, Jun. 2018, Japanese, 特定非営利活動法人 日本食道学会, 宇都宮, Domestic conference胸腔鏡下食道切除術後の合併症の予後Poster presentation
- 第43回日本外科系連合学会学術集会, Jun. 2018, Japanese, 一般社団法人 学会支援機構内日本外科系連合学会事務局, 東京, Domestic conferenceマルチライフ~女性外科医と家庭の真の両立を目指して~Public symposium
- 第72回日本食道学会学術集会, Jun. 2018, Japanese, 特定非営利活動法人 日本食道学会, 宇都宮, Domestic conferenceQOLに考慮した有茎空腸再建術の工夫Others
- 第72回日本食道学会学術集会, Jun. 2018, Japanese, 特定非営利活動法人 日本食道学会, 宇都宮, Domestic conferenceMIEにおいて3D内視鏡システムは反回神経麻痺を減少させるか?Others
- 第43回日本外科系連合学会学術集会, Jun. 2018, Japanese, 一般社団法人 学会支援機構内日本外科系連合学会事務局, 東京, Domestic conference3D/HDおよび2D/4Kモニターが内視鏡外科医の手術手技にもたらす効果Public symposium
- 第6回がんと代謝研究会, May 2018, Japanese, がんと代謝研究会, 奄美大島, Domestic conference放射線がもたらす腫瘍微小環境の変化の解析Poster presentation
- 7th Lap Colorectal Advanced Seminar, May 2018, Japanese, コヴィディエンジャパン株式会社, 東京, Domestic conference腹腔鏡下右側横行結腸癌手術(司会)Others
- 第72回手術手技研究会, May 2018, Japanese, 手術手技研究会事務局, 徳島, Domestic conference肺への浸潤を伴う食道癌に対する胸腔鏡下食道切除術Others
- 第72回手術手技研究会, May 2018, Japanese, 手術手技研究会事務局, 徳島, Domestic conference当科におけるTa-TMEの手術手技と手術成績Others
- 第201回近畿外科学会, May 2018, Japanese, 近畿外科学会事務局, 大阪, Domestic conference当院における十二指腸LECSの検討Oral presentation
- 第27回日本癌病態治療研究会, May 2018, Japanese, NPO法人 日本癌病態治療研究会事務局, 千葉, Domestic conference直腸癌術前化学療法の腫瘍免疫因子の発現動態の解析Public symposium
- 第72回手術手技研究会, May 2018, Japanese, 手術手技研究会事務局, 徳島, Domestic conference直腸癌手術における術中内視鏡検査と経肛門ドレーンの有効性Others
- 第28回日本サイトメトリー学会学術集会, May 2018, Japanese, 一般社団法人日本サイトメトリー学会, 東京, Domestic conference消化器癌患者におけるT細胞の刺激応答性の新規評価方法Poster presentation
- 第72回手術手技研究会, May 2018, Japanese, 手術手技研究会事務局, 徳島, Domestic conference十二指腸腫瘍に対す腹腔鏡内視鏡合同手術についてPoster presentation
- 第39回癌免疫外科研究会, May 2018, Japanese, 癌免疫外科研究会, 岐阜, Domestic conference腫瘍再発モデルにおける末梢血中の骨髄由来抑制細胞(MDSC)の推移Oral presentation
- 第6回がんと代謝研究会, May 2018, Japanese, がんと代謝研究会, 奄美大島, Domestic conference腫瘍再発モデルにおける末梢血中の骨髄由来抑制細胞(MDSC)の推移Poster presentation
- 第201回近畿外科学会, May 2018, Japanese, 近畿外科学会事務局, 大阪, Domestic conference酸性洗剤飲用により完全閉塞をきたした腐食性食道炎の一例Oral presentation
- 第201回近畿外科学会, May 2018, Japanese, 近畿外科学会事務局, 大阪, Domestic conference左結腸動脈温存D3郭清の定型化:当院での試みOral presentation
- 第201回近畿外科学会, May 2018, Japanese, 近畿外科学会事務局, 大阪, Domestic conference結腸癌における腹腔鏡下手術Public discourse
- 第27回日本癌病態治療研究会, May 2018, Japanese, NPO法人 日本癌病態治療研究会事務局, 千葉, Domestic conference癌患者におけるT細胞の刺激応答性の評価Others
- 第72回手術手技研究会, May 2018, Japanese, 手術手技研究会事務局, 徳島, Domestic conference開腹Hartmann術後の人工肛門形成状態に対する腹腔鏡下人工肛門閉鎖術の有効性Poster presentation
- 第201回近畿外科学会, May 2018, Japanese, 近畿外科学会事務局, 大阪, Domestic conferenceFDGの高度集積を認めた食道偽憩室に起因する食道腫瘤の一例Oral presentation
- 第118回日本外科学会定期学術集会, Apr. 2018, Japanese, 一般社団法人日本外科学会, 東京, Domestic conference腹壁瘢痕ヘルニアinlay-meshにおける腹腔鏡手術と開腹手術の比較Poster presentation
- 第118回日本外科学会定期学術集会, Apr. 2018, Japanese, 一般社団法人日本外科学会, 東京, Domestic conference腹臥位での胸腔鏡手術による食道癌根治術Oral presentation
- 第118回日本外科学会定期学術集会, Apr. 2018, Japanese, 一般社団法人日本外科学会, 東京, Domestic conference食道癌内視鏡的粘膜下層剥離術後非治療切除症例に対する追加治療例の検討Others
- 第118回日本外科学会定期学術集会, Apr. 2018, Japanese, 一般社団法人日本外科学会, 東京, Domestic conference食道癌手術における合併症および長期予後予測因子としてのSurgical Apgar ScorePublic symposium
- 第118回日本外科学会定期学術集会, Apr. 2018, Japanese, 一般社団法人日本外科学会, 東京, Domestic conference高齢者進行胃癌に対する術前化学療法の安全性Poster presentation
- 第118回日本外科学会定期学術集会, Apr. 2018, Japanese, 一般社団法人日本外科学会, 東京, Domestic conference高齢者の胃癌治癒切除後の予後予測因子におけるCONUT scoreの有用性Public symposium
- 第118回日本外科学会定期学術集会, Apr. 2018, Japanese, 一般社団法人日本外科学会, 東京, Domestic conference胸腔鏡下食道切除術に対する3D内視鏡の導入と治療成績Others
- 第118回日本外科学会定期学術集会, Apr. 2018, Japanese, 一般社団法人日本外科学会, 東京, Domestic conference下部進行直腸癌に対する術前化学放射線療法+選択的側方郭清の治療成績Others
- AACR Annual Meeting 2018, Apr. 2018, English, American Association for Cancer Research, Chicago, International conferenceThe induction of PD-L1 positive immune cells and CD8-positive T lymphocytes by neoadjuvant chemoradiotherapy for rectal cancerPoster presentation
- SAGES2018, Apr. 2018, English, Society of American Gastrointestinal and Endoscopic Surgeons, Washington, International conferenceSurgical strategy for splenic flexure cancer.Others
- 第90回日本胃癌学会総会, Mar. 2018, Japanese, 日本胃癌学会, 横浜, Domestic conference神経内分泌細胞成分を伴う胃癌に対する集学的治療の有用性Poster presentation
- 第1回兵庫腹腔鏡下大腸切除研究会, Mar. 2018, Japanese, ジョンソンエンドジョンソン株式会社, 神戸, Domestic conference症例提示および製品紹介Oral presentation
- 第1回兵庫腹腔鏡下大腸切除研究会, Mar. 2018, Japanese, ジョンソンエンドジョンソン株式会社, 神戸, Domestic conference症例提示(1)『ポート挿入~血管処理』Others
- 第51回制癌剤適応研究会, Mar. 2018, Japanese, 制癌剤適応研究会, 下呂, Domestic conference術前化学放射線療法を施行した進行直腸癌におけるmodified Glassgow Prognostic Scoreを用いた治療効果予測Oral presentation
- 第51回制癌剤適応研究会, Mar. 2018, Japanese, 制癌剤適応研究会, 下呂, Domestic conference高齢者食道癌における術前補助化学療法についての検討Oral presentation
- 第90回日本胃癌学会総会, Mar. 2018, Japanese, 日本胃癌学会, 横浜, Domestic conference高齢者の胃癌切除症例における術前末梢血の総リンパ球数の臨床的意義Oral presentation
- 第90回日本胃癌学会総会, Mar. 2018, Japanese, 日本胃癌学会, 横浜, Domestic conference高齢者の胃癌切除後の予後予測における血小板/リンパ球比の有用性Oral presentation
- 第51回制癌剤適応研究会, Mar. 2018, Japanese, 制癌剤適応研究会, 下呂, Domestic conference局所進行直腸癌における術前化学放射線療法後の免疫細胞の解析Oral presentation
- 第51回制癌剤適応研究会, Mar. 2018, Japanese, 制癌剤適応研究会, 下呂, Domestic conference化学療法後に胃切除術を行った進行胃癌症例の検討Oral presentation
- 第51回制癌剤適応研究会, Mar. 2018, Japanese, 制癌剤適応研究会, 下呂, Domestic conferenceStageIV胃癌に対するconversion surgeryの適応と予後の検討Oral presentation
- 第90回日本胃癌学会総会, Mar. 2018, Japanese, 日本胃癌学会, 横浜, Domestic conference80歳以上の胃癌患者に対する術前補助化学療法の経験Poster presentation
- 第14回日本消化管学会総会学術集会, Feb. 2018, Japanese, 日本消化管学会, 東京, Domestic conference発生と解剖に基づいた脾弯曲癌に対する腹腔鏡下結腸間膜全切除Public symposium
- 第14回日本消化管学会総会学術集会, Feb. 2018, Japanese, 日本消化管学会, 東京, Domestic conference当科における噴門部GISTの手術成績と治療戦略の検討Public symposium
- 第14回日本消化管学会総会学術集会, Feb. 2018, Japanese, 日本消化管学会, 東京, Domestic conference神経内分泌細胞成分を含む胃癌に対する集学的治療の有用性Public symposium
- 第7回兵庫大腸ビデオカンファレンス, Feb. 2018, Japanese, コヴィディエンジャパン株式会社, 神戸, Domestic conferenceビデオカンファレンスOthers
- 第30回日本内視鏡外科学会総会, Dec. 2017, Japanese, 日本内視鏡外科学会, 京都, Domestic conference腹臥位食道癌手術における左右上縦隔郭清Public symposium
- 第30回日本内視鏡外科学会総会, Dec. 2017, Japanese, 日本内視鏡外科学会, 京都, Domestic conference進行胃癌に対する腹腔鏡下胃切除術の短期、長期成績 開腹術との比較Public symposium
- 第21回バイオ治療法研究会学術集会, Dec. 2017, Japanese, バイオ治療研究会, 福岡, Domestic conference術後腹膜炎が肺転移の予後に及ぼす影響とその免疫学的検討Oral presentation
- 第21回バイオ治療法研究会学術集会, Dec. 2017, Japanese, バイオ治療研究会, 福岡, Domestic conference腫瘍抗原導入DCGを用いた抗原特異的抗腫瘍免疫活性化Oral presentation
- 第30回日本内視鏡外科学会総会, Dec. 2017, Japanese, 日本内視鏡外科学会, 京都, Domestic conference高齢者食道癌に対する胸腔鏡下手術成績の検討Poster presentation
- 第30回日本内視鏡外科学会総会, Dec. 2017, Japanese, 日本内視鏡外科学会, 京都, Domestic conference横行結腸癌に対する腹腔鏡下手術における発生学的観点からみた至適切除範囲とアプローチ法についてPoster presentation
- 第1回神戸消化器学術講演会, Nov. 2017, Japanese, ミヤリサン製薬株式会社, 神戸, Domestic conference閉会の挨拶Others
- 第79回日本臨床外科学会総会, Nov. 2017, Japanese, 日本臨床外科学会, 東京, Domestic conference直腸癌術前化学放射線療法の腫瘍免疫因子の発現動態の解析[Invited]Nominated symposium
- 第28回日本消化器癌発生学会, Nov. 2017, Japanese, 日本消化器癌発生学会, 熊本, Domestic conference消化器癌患者におけるT細胞の刺激応答性の評価方法の検討Oral presentation
- 第28回日本消化器癌発生学会, Nov. 2017, Japanese, 日本消化器癌発生学会, 熊本, Domestic conference術後腹膜炎が肺転移の予後に及ぼす影響とその免疫学的検討Oral presentation
- 第28回日本消化器癌発生学会, Nov. 2017, Japanese, 日本消化器癌発生学会, 熊本, Domestic conference腫瘍再発モデルにおける末梢血中の骨髄由来抑制細胞(MDSC)の推移Oral presentation
- 第28回日本消化器癌発生学会, Nov. 2017, Japanese, 日本消化器癌発生学会, 熊本, Domestic conference腫瘍抗原導入DCGを用いた抗腫瘍免疫活性化の検討Oral presentation
- 第47回胃外科・術後障害研究会, Nov. 2017, Japanese, 胃外科・術後研究会, 横浜, Domestic conference高齢者進行胃癌症例治療成績からみた戦略Poster presentation
- 第79回日本臨床外科学会総会, Nov. 2017, Japanese, 日本臨床外科学会, 東京, Domestic conference高齢者の胃癌切除後における炎症に基づく予後予測スコアの有用性Oral presentation
- 第79回日本臨床外科学会総会, Nov. 2017, Japanese, 日本臨床外科学会, 東京, Domestic conferenceStage IV胃癌に対するconversion surgeryの適応と治療成績Public symposium
- JDDW2017, Oct. 2017, Japanese, 日本消化器関連学会機構, 福岡, Domestic conference閉塞性大腸癌に対する術前大腸ステント留置の有用性の検討Poster presentation
- JDDW2017, Oct. 2017, Japanese, 日本消化器関連学会機構, 福岡, Domestic conference大腸ESD後穿孔症例に対するクリッピング閉鎖の有効性についてPoster presentation
- JDDW2017, Oct. 2017, Japanese, 日本消化器関連学会機構, 福岡, Domestic conference早期胃癌に対するESD後の追加外科切除症例の検討Poster presentation
- JDDW2017, Oct. 2017, Japanese, 日本消化器関連学会機構, 福岡, Domestic conference食道切除術におけるSurgical Apgar Scoreの有用性の検討Poster presentation
- 第55回日本癌治療学会学術総会, Oct. 2017, Japanese, 日本癌治療学会, 横浜, Domestic conference高齢者食道癌における術前補助化学療法の検討Poster presentation
- JDDW2017, Oct. 2017, Japanese, 日本消化器関連学会機構, 福岡, Domestic conference高齢者食道癌における胸腔鏡下手術に関する検討(優秀演題)Poster presentation
- JDDW2017, Oct. 2017, Japanese, 日本消化器関連学会機構, 福岡, Domestic conference高齢者胃癌の術後合併症発生の予測因子としてのCONUT scoreの有用性Poster presentation
- JDDW2017, Oct. 2017, Japanese, 日本消化器関連学会機構, 福岡, Domestic conference高齢者の胃癌切除症例における術前末梢血の白血球系細胞数の臨床的意義Poster presentation
- 第55回日本癌治療学会学術総会, Oct. 2017, Japanese, 日本癌治療学会, 横浜, Domestic conference高齢者の胃癌切除後における炎症に基づく予後予測スコアの有用性Oral presentation
- JDDW2017, Oct. 2017, Japanese, 日本消化器関連学会機構, 福岡, Domestic conference回腸双孔式人工肛門閉鎖における創部線状縫合閉鎖と巾着縫合閉鎖の比較Poster presentation
- JDDW2017, Oct. 2017, Japanese, 日本消化器関連学会機構, 福岡, Domestic conferenceStage IV胃癌に対するconversion surgeryの適応と治療成績Poster presentation
- 第55回日本癌治療学会学術総会, Oct. 2017, Japanese, 日本癌治療学会, 横浜, Domestic conferencecStageII/III胃癌に対する術前化学療法の有用性Poster presentation
- JDDW2017, Oct. 2017, English, 日本消化器関連学会機構, 福岡, Domestic conferenceClinical outcomes of selective lateral pelvic lymph node dissection with preoperative chemoradiotherapy for lower rectal cancerPublic symposium
- 第30回近畿内視鏡外科研究会, Sep. 2017, Japanese, 近畿内視鏡外科研究会, 大阪, Domestic conference腹腔鏡下食道亜全摘術を施行した食道炎症性腫瘤の1例Oral presentation
- 第30回近畿内視鏡外科研究会, Sep. 2017, Japanese, 近畿内視鏡外科研究会, 大阪, Domestic conference腹腔鏡下胃切除後にPetersen's herniaをきたした3例Oral presentation
- 第30回近畿内視鏡外科研究会, Sep. 2017, Japanese, 近畿内視鏡外科研究会, 大阪, Domestic conference当科におけるTAMIS併用直腸癌手術の経験と今後の課題Public symposium
- 第200回近畿外科学会, Sep. 2017, Japanese, 近畿外科学会, 京都, Domestic conference術前診断し腹腔鏡下小腸部分切除術をおこなった小腸血管腫の1例Oral presentation
- 第200回近畿外科学会, Sep. 2017, Japanese, 近畿外科学会, 京都, Domestic conference術前化学放射線療法を施行した局所進行肛門管癌に対して有茎腹直筋皮弁再建が有用であった1例Oral presentation
- 第200回近畿外科学会, Sep. 2017, Japanese, 近畿外科学会, 京都, Domestic conference回腸ストマ閉鎖における創部環状閉鎖と線上閉鎖との比較Oral presentation
- 第200回近畿外科学会, Sep. 2017, Japanese, 近畿外科学会, 京都, Domestic conference炎症性食道腫瘤の1例Oral presentation
- 第30回近畿内視鏡外科研究会, Sep. 2017, Japanese, 近畿内視鏡外科研究会, 大阪, Domestic conferenceイレウス症状を呈し腹腔鏡下に切除した小腸神経内分泌腫瘍の1例Oral presentation
- 6th Reduced Port Surgery Forum 2017 in Oita、第11回 単孔式内視鏡手術研究会、第17回 Needlescopic Surgery Meeting, Aug. 2017, Japanese, 単孔式内視鏡手術研究会, 大分, Domestic conference右側結腸癌に対するReduced port Surgeryの短期成績についてOral presentation
- 日本・モンゴル国際消化器がんシンポジウム, Aug. 2017, English, 中山がん研究所, ウランバートル, モンゴル, International conferenceLaparoscopic complete mesocolic excision for splenic flexure cancer based on embryologyOral presentation
- 日本・モンゴル国際消化器がんシンポジウム, Aug. 2017, English, 中山がん研究所, ウランバートル, モンゴル, Domestic conferenceComparison of two-and three-dimensional display for performance of laparoscopic total gastrectomy for gastric cancerOral presentation
- 第72回日本消化器外科学会総会, Jul. 2017, Japanese, 日本消化器外科学会, 金沢, Domestic conference閉塞性大腸癌に対するステント留置の有用性Oral presentation
- 第72回日本消化器外科学会総会, Jul. 2017, Japanese, 日本消化器外科学会, 金沢, Domestic conference当院における進行下部直腸癌に対する側方リンパ節郭清についてPublic symposium
- 第87回大腸癌研究会, Jul. 2017, Japanese, 大腸癌研究会, 四日市, Domestic conference大腸ESD後穿孔症例に対するクリッピング閉鎖の有効性の検討Oral presentation
- 第72回日本消化器外科学会総会, Jul. 2017, Japanese, 日本消化器外科学会, 金沢, Domestic conference食道癌手術におけるSurgical Apgar Scoreと合併症予測因子Public symposium
- 第72回日本消化器外科学会総会, Jul. 2017, Japanese, 日本消化器外科学会, 金沢, Domestic conference食道癌cStageII/IIIで術前補助化学療法を施行した症例におけるCRP/Albの有用性Oral presentation
- 第72回日本消化器外科学会総会, Jul. 2017, Japanese, 日本消化器外科学会, 金沢, Domestic conference術前抗血栓療法中の胃切除患者に対する周術期抗血栓療法の検討Oral presentation
- 第87回大腸癌研究会, Jul. 2017, Japanese, 大腸癌研究会, 四日市, Domestic conference術前化学放射線療法施行直腸癌における免疫関連因子の発現動態の検討Oral presentation
- 第72回日本消化器外科学会総会, Jul. 2017, Japanese, 日本消化器外科学会, 金沢, Domestic conference周術期腹膜炎に伴う免疫抑制メカニズムの解明と治療:マウスモデルでの検討Oral presentation
- 第72回日本消化器外科学会総会, Jul. 2017, Japanese, 日本消化器外科学会, 金沢, Domestic conference高齢者胃癌手術後の予後予測におけるCONUT scoreの有効性Oral presentation
- 第72回日本消化器外科学会総会, Jul. 2017, Japanese, 日本消化器外科学会, 金沢, Domestic conference血管吻合付有茎空腸再建術の工夫と治療成績Public symposium
- 第72回日本消化器外科学会総会, Jul. 2017, Japanese, 日本消化器外科学会, 金沢, Domestic conference局所進行直腸癌における術前化学放射線療法後のPD-L1発現の変化Oral presentation
- 第72回日本消化器外科学会総会, Jul. 2017, Japanese, 日本消化器外科学会, 金沢, Domestic conference胸腔鏡下食道切除術における術後合併症と予後との検討Oral presentation
- 第72回日本消化器外科学会総会, Jul. 2017, Japanese, 日本消化器外科学会, 金沢, Domestic conference化学療法施行後に手術を行った高度進行胃癌の検討Oral presentation
- 第72回日本消化器外科学会総会, Jul. 2017, Japanese, 日本消化器外科学会, 金沢, Domestic conference胃GISTに対するLECS(laparoscopy and endoscopy cooperative surgery)により切除された胃壁長の検討Oral presentation
- 第71回日本食道学会学術集会, Jun. 2017, Japanese, 日本食道学会, 軽井沢, Domestic conference腹腔鏡下食道癌手術手技の施設内統一と成績Poster presentation
- 第26回癌病態治療研究会, Jun. 2017, Japanese, 日本癌病態治療研究会, 横浜, Domestic conference内視鏡的粘膜下層剥離術後非治療切除症例に対する食道切除の意義とその役割Public symposium
- 第71回日本食道学会学術集会, Jun. 2017, Japanese, 日本食道学会, 軽井沢, Domestic conference食道非上皮性腫瘍の術前診断とその有用性Public symposium
- 第71回日本食道学会学術集会, Jun. 2017, Japanese, 日本食道学会, 軽井沢, Domestic conference食道癌同時性重複癌症例に対する同時手術治療症例の検討Poster presentation
- 第42回日本外科系連合学会学術集会, Jun. 2017, Japanese, 日本外科系連合学会, 徳島, Domestic conference食道癌手術における呼吸器合併症の低減を目指したmultidisciplinary team manegementPublic symposium
- 第26回癌病態治療研究会, Jun. 2017, Japanese, 日本癌病態治療研究会, 横浜, Domestic conference術前化学放射線療法を施行した進行直腸癌におけるmodified Glasgow Prognostic Scoreを用いた治療効果予測Public symposium
- 第27回日本サイトメトリー学会学術集会, Jun. 2017, Japanese, 日本サイトメトリー学会, 神戸, Domestic conference腫瘍抗原導入DCGを用いた抗腫瘍免疫活性化の検討Oral presentation
- 第71回日本食道学会学術集会, Jun. 2017, Japanese, 日本食道学会, 軽井沢, Domestic conference高齢者食道癌に対する腹腔鏡下手術の治療成績の検討Poster presentation
- 第60回関西胸部外科学会学術集会, Jun. 2017, Japanese, 日本胸部外科学会, 大阪, Domestic conference高齢者食道癌に対する胸腔鏡下手術の治療成績の検討Public symposium
- 第26回癌病態治療研究会, Jun. 2017, Japanese, 日本癌病態治療研究会, 横浜, Domestic conference局所進行直腸癌術前化学放射線療法の免疫チェクポイント分子の変化Public symposium
- 第39回日本癌局所療法研究会, Jun. 2017, Japanese, 日本癌局所療法研究会, 京都, Domestic conferenceTmab+XP療法が著効しConversion surgeryを施行した胃癌腹膜播種の一例Oral presentation
- 第26回癌病態治療研究会, Jun. 2017, Japanese, 日本癌病態治療研究会, 横浜, Domestic conferenceStage IV胃癌に対するConversion surgeryの適応と治療成績Public symposium
- 第25回欧州内視鏡外科会議(EAES), Jun. 2017, English, EAES, フランクフルト, ドイツ, International conferenceSingle incision laparoscopic colectomy for colon cancer in a patient with situs inversus totalis;A case reportPoster presentation
- 第39回日本癌局所療法研究会, Jun. 2017, Japanese, 日本癌局所療法研究会, 京都, Domestic conferenceS-1/CDDP療法後に手術を施行し長期予後を得ている腹膜播種陽性胃癌の1例Oral presentation
- 第25回欧州内視鏡外科会議(EAES), Jun. 2017, English, EAES, フランクフルト, ドイツ, International conferenceNext generation laparoscopic surgery using EMARO(Endoscopic Manipulator Robot)and a 3D endoscope systemPoster presentation
- 第25回欧州内視鏡外科会議(EAES), Jun. 2017, English, EAES, フランクフルト, ドイツ, International conferenceEmbryological consideration of laparoscopic completeOral presentation
- 第25回欧州内視鏡外科会議(EAES), Jun. 2017, English, EAES, フランクフルト, ドイツ, International conferenceComparison of operative skill using two -and three-dimensional monitor during laparoscopic phantom tasks by the position trackerPoster presentation
- 第27回日本サイトメトリー学会学術集会, Jun. 2017, Japanese, 日本サイトメトリー学会, 神戸, Domestic conferenceB16F10細胞を用いた再発モデルにおける末梢血中MDSCの経時的測定の有用性Oral presentation
- 第71回手術手技研究会, May 2017, Japanese, 手術手技研究会, 名古屋, Domestic conference鉗子操作の3次元軌跡解析を用いた内視鏡外科手術の適正評価法の開発と技術評価が学習効果に及ぼす影響に関する研究Others
- 第38回癌免疫外科研究会, May 2017, Japanese, 癌免疫外科研究会, 倉敷, Domestic conference直腸癌における腫瘍免疫関連因子の発現動態と化学療法前後の腫瘍浸潤CD8陽性T細胞の発現の変化と組織学的効果判定の関連の検討Oral presentation
- 第38回癌免疫外科研究会, May 2017, Japanese, 癌免疫外科研究会, 倉敷, Domestic conference胆癌状態における腫瘍誘導性骨髄由来抑制細胞(MDSC)を与える影響Oral presentation
- 第71回手術手技研究会, May 2017, Japanese, 手術手技研究会, 名古屋, Domestic conference大動脈食道瘻手術における消化器外科医の役割‐食道切除と再建を中心に‐Oral presentation
- 第38回癌免疫外科研究会, May 2017, Japanese, 癌免疫外科研究会, 倉敷, Domestic conference穿孔性腹膜炎が肺転移の予後に及ぼす影響とその免疫学的検討Oral presentation
- 第71回手術手技研究会, May 2017, Japanese, 手術手技研究会, 名古屋, Domestic conference進行横行結腸癌に対する頭側アプローチによる腹腔鏡下拡大結腸右半切除術Oral presentation
- 第38回癌免疫外科研究会, May 2017, Japanese, 癌免疫外科研究会, 倉敷, Domestic conference腫瘍抗原導入DCGを用いた抗原特異的な抗腫瘍免疫活性化Oral presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference腹腔鏡下幽門側胃切除術における簡便な手術難易度を示す指標に関する検討Oral presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference腹腔鏡下右側結腸切除術においてReduced Port Surgeryをいかに教育するか?Poster presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference腹腔鏡下S状結腸・直腸癌における下腸間膜動脈high ligationの重要性Poster presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference動作解析システムを用いた3D腹腔鏡下での手術手技の検討Oral presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference当院における腹腔鏡下胃全摘術における食道空腸吻合法の検討Poster presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference直腸癌の術前化学放射線療法施行例における免疫関連因子の検討Poster presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference担癌状態におけるmyeloid derived suppressor cellsの治療による変化と治療成績への影響Poster presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference大腸ESD後穿孔症例に対するクリッピング閉鎖の有用性についてPoster presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference大腸ESD後穿孔症例に対するクリッピング閉鎖の有効性についてOral presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference消化器外科医からみた大動脈食道瘻の治療戦略Oral presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference根治切除を施行したpStageII-III胃癌に対するS-1術後補助化学療法Poster presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference高齢者食道癌に対する術前補助化学療法の治療成績Oral presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference呼吸器合併症低減をめざした食道癌手術とmultidisciplinary team managementPoster presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference血流に配慮した食道再建術の工夫Poster presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference胸腔鏡下食道癌手術症例における術後合併症の発生と予後の検討Poster presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference患者左右から攻略する腹腔鏡下膵上縁D2郭清Oral presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference下部直腸癌の鼠径リンパ節転移に対する術前化学放射線療法の有用性Poster presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference胃癌肝転移の外科治療の問題点Oral presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference胃癌ESD後の腹腔鏡下胃切除による追加治療Poster presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference胃・十二指腸腫瘍に対するLECS(laparoscopy and endoscopy cooperative surgery)Poster presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference胃GISTに対する腹腔鏡下胃切除の有用性Poster presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conferenceStage IV胃癌に対するConversion surgeryの適応Poster presentation
- 第117回日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会, 横浜, Domestic conference3Dモニターが初心者の内視鏡外科修練にもたらす影響Oral presentation
- 第50回制癌剤適応研究会, Mar. 2017, Japanese, 制癌剤適応研究会, 徳島, Domestic conference大腸癌肝転移に対する術前化学療法の効果とその予後Oral presentation
- 第50回制癌剤適応研究会, Mar. 2017, Japanese, 制癌剤適応研究会, 徳島, Domestic conference局所進行直腸癌における術前化学放射線療法の免疫関連因子への影響Public symposium
- 第89回日本胃癌学会総会, Mar. 2017, English, 一般社団法人 日本胃癌学会, 広島, Domestic conferenceThe significance of surgery following chemotherapy for stage IV gastric cancer (StageIV胃癌に対する化学療法後の外科切除の意義)Poster presentation
- 第89回日本胃癌学会総会, Mar. 2017, Japanese, 一般社団法人 日本胃癌学会, 広島, Domestic conferenceThe laparoscopic lymphadenectomy along proximal splenic artery from patient's left side(患者左から攻略する腹腔鏡下脾動脈近位側郭清)Others
- 第89回日本胃癌学会総会, Mar. 2017, Japanese, 一般社団法人 日本胃癌学会, 広島, Domestic conferenceSurveillance and treatment for gastric cancer after radical esophagectomy(当科における食道切除後再建胃管癌の検討)Poster presentation
- 第89回日本胃癌学会総会, Mar. 2017, Japanese, 一般社団法人 日本胃癌学会, 広島, Domestic conferencePostoperative pneumonia after gastrectomy for elderly gastric cancer patients(高齢者胃癌の術後肺炎の長期予後に及ぼす影響)Poster presentation
- 第89回日本胃癌学会総会, Mar. 2017, Japanese, 一般社団法人 日本胃癌学会, 広島, Domestic conferenceLECS(laparoscopy and endoscopy cooperative surgery) for gastric GIST(胃・十二指腸腫瘍に対するLECS(laparoscopy and endoscopy cooperative surgery)Oral presentation
- SAGES 2017 Annual Meeting, Mar. 2017, English, Society of American Gastrointestinal and Endoscopic Surgeons, HOUSTON, USA, International conferenceLAPAROSCOPIC COMPLETE MESOCOLIC EXCISION FOR RIGHT-SIDED COLON CANCER USING A CRANIAL APPROACH: EMBRYOLOGICAL AND ANATOMICAL CONSIDERATIONOthers
- 第89回日本胃癌学会総会, Mar. 2017, Japanese, 一般社団法人 日本胃癌学会, 広島, Domestic conferenceClinicopathologic Study of Gastric Stump Cancer after Proximal Gastrectomy(噴門側胃切除術後の残胃の癌の特徴)Poster presentation
- 第13回日本消化管学会総会学術集会, Feb. 2017, Japanese, 日本消化管学会, 名古屋, Domestic conferenceHER2陽性胃癌に対するTrastuzumabを併用した集学的治療Public symposium
- 第86回大腸癌研究会, Jan. 2017, Japanese, 大腸癌研究会, 盛岡, Domestic conference腹腔鏡下直腸低位前方切除術を安全に施行するための工夫Oral presentation
- 第9回日本ロボット外科学会学術集会, Jan. 2017, Japanese, J-robo 日本ロボット外科学会 事務局, 佐賀, Domestic conferenceロボット支援幽門側胃切除術における助手ポートからの超音波凝固切開装置使用の有用性Oral presentation
- 第9回日本ロボット外科学会学術集会, Jan. 2017, Japanese, J-robo 日本ロボット外科学会 事務局, 佐賀, Domestic conferenceEMARO(Endoscope Manipulate Robot)と3D内視鏡による次世代の腹腔鏡下手術についてOral presentation
- 第29回日本内視鏡外科学会総会, Dec. 2016, Japanese, 一般社団法人 日本内視鏡外科学会, 横浜, Domestic conference腹腔鏡下直腸癌手術における3D内視鏡の有用性Oral presentation
- 第29回日本内視鏡外科学会総会, Dec. 2016, Japanese, 一般社団法人 日本内視鏡外科学会, 横浜, Domestic conference腹腔鏡下中結腸動静脈郭清における出血をさせないための工夫Oral presentation
- 第29回日本内視鏡外科学会総会, Dec. 2016, Japanese, 一般社団法人 日本内視鏡外科学会, 横浜, Domestic conference高齢者胃癌に対する腹腔鏡下胃切除術の手術成績の検討Oral presentation
- 第29回日本内視鏡外科学会総会, Dec. 2016, Japanese, 一般社団法人 日本内視鏡外科学会, 横浜, Domestic conference胸腔鏡下食道切除術に対する3D内視鏡の有用性と治療成績Oral presentation
- 第20回バイオ治療法研究会学術集会, Dec. 2016, Japanese, 特定非営利活動法人環瀬戸内自然免疫ネットワーク, 博多, Domestic conference外科切除のmyeloid derived suppressor cellsに対する影響と臨床的意義Oral presentation
- 第29回日本内視鏡外科学会総会, Dec. 2016, Japanese, 一般社団法人 日本内視鏡外科学会, 横浜, Domestic conferenceSiewert TypeII型食道胃接合部腺癌に対するロボット支援下経裂孔的下縦隔郭清の有用性Public symposium
- 第29回日本内視鏡外科学会総会, Dec. 2016, Japanese, 一般社団法人 日本内視鏡外科学会, 横浜, Domestic conference3ステップ法による腹腔鏡下脾弯曲授動の定型化Oral presentation
- 第24回日本消化器関連学会週間(JDDW2016), Nov. 2016, Japanese, JDDW 2016 運営委員会, 神戸, Domestic conference発生学的観点から見た横行結腸切除の特殊性・困難性と、安全・確実に腹腔鏡下D3横行結腸切除を行うための工夫Public symposium
- 第71回日本大腸肛門病学会学術集会, Nov. 2016, Japanese, 日本大腸肛門病学会事務局, 三重, Domestic conference直腸癌の術前化学放射線療法の免疫関連因子の検討Oral presentation
- 第78回日本臨床外科学会総会, Nov. 2016, Japanese, 日本臨床外科学会 事務局, 東京, Domestic conference超高齢者胃癌に対する胃切除術の適応Public symposium
- 第78回日本臨床外科学会総会, Nov. 2016, Japanese, 日本臨床外科学会 事務局, 東京, Domestic conference進行食道疣状扁平上皮癌の1例Oral presentation
- 第78回日本臨床外科学会総会, Nov. 2016, Japanese, 日本臨床外科学会 事務局, 東京, Domestic conference3D映像が内視鏡外科手術トレーニングに及ぼす影響の検討Oral presentation
- 第46回胃外科・術後障害研究会, Oct. 2016, Japanese, 胃外科・術後障害研究会, 米子, Domestic conference術前抗血栓療法中の胃切除患者に対する周術期抗血栓療法の検討Oral presentation
- 第54回日本癌治療学会学術集会, Oct. 2016, Japanese, 一般社団法人 日本癌治療学会, 横浜, Domestic conference高齢者の胃癌切除後の呼吸器合併症への予後への影響についての検討Public symposium
- 8th AASD Scientific Meeting, Oct. 2016, English, Taipei, Taiwan, International conferenceThe role of casein kinase 2 in ER stress associated pancreatic β cell failureOral presentation
- 第54回日本癌治療学会学術集会, Oct. 2016, Japanese, 一般社団法人 日本癌治療学会, 横浜, Domestic conferenceStageIV胃癌に対する外科切除例の予後規定因子に関する検討Public symposium
- 第29回近畿内視鏡外科研究会, Sep. 2016, Japanese, 近畿内視鏡外科研究会事務局, 京都, Domestic conference腹臥位食道癌手術における左上縦隔郭清の定型化Public symposium
- 第27回日本消化器癌発生学会総会, Sep. 2016, Japanese, 日本消化器癌発生学会, 鹿児島, Domestic conference直腸癌の術前化学放射線療法施行例における免疫関連因子の検討Oral presentation
- 第27回日本消化器癌発生学会総会, Sep. 2016, Japanese, 日本消化器癌発生学会, 鹿児島, Domestic conference担癌状態における骨髄由来抑制細胞(MDSC)の治療による変化とその治療成績への影響Oral presentation
- 第25回消化器疾患病態治療研究会, Sep. 2016, Japanese, 消化器疾患病態治療研究会, 高崎市, International conference神経内分泌細胞成分を伴う胃癌に対する集学的治療の有用性Oral presentation
- 第27回日本消化器癌発生学会総会, Sep. 2016, Japanese, 日本消化器癌発生学会, 鹿児島, Domestic conference手術治療をおこなった食道GISTの2例Oral presentation
- 第25回消化器疾患病態治療研究会, Sep. 2016, Japanese, 消化器疾患病態治療研究会, 高崎市, International conference胃GIST に対するLECS(laparoscopy and endoscopy cooperative surgery)の検討Oral presentation
- 第29回近畿内視鏡外科研究会, Sep. 2016, Japanese, 近畿内視鏡外科研究会事務局, 京都, Domestic conference胃GISTに対するLECS(laparoscopy and endoscopy cooperative surgery)症例の検討Public symposium
- 第27回日本消化器癌発生学会総会, Sep. 2016, Japanese, 日本消化器癌発生学会, 鹿児島, Domestic conferenceHER2陽性胃癌に対するTrastuzumab併用化学療法後の外科切除の安全性と有効性Oral presentation
- 第27回日本消化器癌発生学会総会, Sep. 2016, Japanese, 日本消化器癌発生学会, 鹿児島, Domestic conferenceDOGにおけるCD40-CD40L interaction の抗腫瘍効果への影響Oral presentation
- 第27回日本消化器癌発生学会総会, Sep. 2016, Japanese, 日本消化器癌発生学会, 鹿児島, Domestic conferenceAllogeneic DCGを用いた抗腫瘍免疫活性化の検討Oral presentation
- 第29回近畿内視鏡外科研究会, Sep. 2016, Japanese, 近畿内視鏡外科研究会事務局, 京都, Domestic conference3ステップ法による腹腔鏡下結腸脾弯曲授動Oral presentation
- 第29回近畿内視鏡外科研究会, Sep. 2016, Japanese, 近畿内視鏡外科研究会事務局, 京都, Domestic conference3Dモニターが初心者の内視鏡外科トレーニングにもたらす影響Public symposium
- 第10回単孔式内視鏡手術研究会/第14回 Needlescopic Surgery Meeting, Aug. 2016, Japanese, 単孔式内視鏡手術研究会事務局, 大阪, Domestic conference右側結腸癌に対する単孔式腹腔鏡下手術の有用性についてOral presentation
- 第71回日本消化器外科学会総会, Jul. 2016, Japanese, 一般社団法人 日本消化器外科学会, 徳島, Domestic conference腹腔鏡下胃切除における胃切離ラインの決定:新たな知見に基づく術中超音波(ILUS)の有用性(ポスター発表)Poster presentation
- 第71回日本消化器外科学会総会, Jul. 2016, Japanese, 徳島大学, 徳島, Domestic conference腹腔鏡下胃切除における胃切離ラインの決定:新たな知見に基づく術中超音波(ILUS)の有用性Public symposium
- 第26回日本サイトメトリー学会学術集会, Jul. 2016, Japanese, 日本サイトメトリー学会, 福岡, Domestic conference担癌状態における腫瘍誘導性骨髄由来抑制細胞(MDSC)の与える影響と治療による変化Oral presentation
- 第85回大腸癌研究会, Jul. 2016, Japanese, 大腸癌研究会, 大阪, Domestic conference後期高齢者大腸癌に対する腹腔鏡手術の有用性Oral presentation
- 第26回日本サイトメトリー学会学術集会, Jul. 2016, Japanese, 日本サイトメトリー学会, 福岡, Domestic conferencealpha-galactosylceramideによるNKT細胞活性化と肝傷害Oral presentation
- 第26回日本サイトメトリー学会学術集会, Jul. 2016, Japanese, 日本サイトメトリー学会, 福岡, Domestic conferenceAllogeneic DCG療法を用いた抗腫瘍免疫活性化の検討Oral presentation
- 第41回日本外科系連合学会学術集会, Jun. 2016, Japanese, 日本外科系連合学会, 大阪, Domestic conference腹臥位食道癌手術におけるエネルギーデバイスの使い分けとコツPublic symposium
- 第41回日本外科系連合学会学術集会, Jun. 2016, Japanese, 日本外科系連合学会, 大阪, Domestic conference胃GISTに対するLECS(laparoscoopy and endoscopy cooperative surgery)の検討Poster presentation
- 24th International congress of the European Association for Endoscopic Surgery, Jun. 2016, English, The European Association for Endoscopic Surgery, Amsterdam, The Netherlands, International conferenceLaparoscopic right hemicolectomy using a cranial approach: Technical tipsOral presentation