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TANAKA HidekazuUniversity Hospital / Cardiovascular MedicineAssociate Professor
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■ Paper- Mar. 2019, J Echocardiogr, 17(1) (1), 17 - 24, EnglishUtility of strain imaging in conjunction with heart failure stage classification for heart failure patient management[Refereed]Scientific journal
- OBJECTIVES: Pulmonary hypertension (PH) is characterized by marked and sustained elevation of pulmonary vascular resistance and pulmonary artery pressure, and subsequent right-sided heart failure. Right ventricular (RV) function and exercise capacity have been recognized as important prognostic factors for PH. Our aim was to investigate RV contractile reserve and exercise capacity during a leg-positive pressure (LPP) maneuver. METHODS: The study population comprised 43 PH patients and 17 normal controls. All patients underwent echocardiography at rest and during LPP stress. Exercise capacity was assessed by 6-minute walk distance for PH patients. RV relative wall thickness was calculated from dividing by RV free wall thickness by basal RV linear dimensions at end-diastole. RV function was calculated by averaging peak speckle-tracking longitudinal strain from the RV free wall. RV contractile reserve was assessed as the difference in RV free wall strain at rest and during LPP stress. Changes in left ventricular stroke volume (ΔSV) during LPP stress were also calculated. RESULTS: ΔSV and RV contractile reserve of PH patients were significantly lower than of controls (3.6 ± 6.0 mL vs 8.5 ± 2.3 mL, and 8.2 ± 11.9% vs 14.5 ± 6.6%; both P < 0.01). RV contractile reserve of PH patients with ΔSV <3.3 mL was significantly lower than of PH patients with ΔSV >3.3 mL (3.9 ± 13.2% vs 12.3 ± 8.9%; P = 0.02). ΔSV had also significant correlation with 6-minute walk distance (r = 0.42, P = 0.006). Multivariate regression analysis showed that RV relative wall thickness was an independent determinant parameter of ΔSV during LPP stress for PH patients (β = 3.2, P = 0.003). CONCLUSIONS: Preload stress echocardiography in response to LPP maneuver, a noninvasive and easy-to-use procedure for routine clinical use, proved to be useful for the assessment of RV contractile reserve and exercise capacity of PH patients.Dec. 2018, Echocardiography (Mount Kisco, N.Y.), 35(12) (12), 1997 - 2004, English, International magazine[Refereed]Scientific journal
- Dec. 2018, Gen Thorac Cardiovasc Surg, EnglishA successful report of mitral valve repair for parachute-like mitral valve in adult[Refereed]Scientific journal
- BACKGROUND: The objective of this study was to investigate the impact of sodium glucose cotransporter type 2 (SGLT2) inhibitors on left ventricular (LV) diastolic function of type 2 diabetes mellitus (T2DM) patients with heart failure (HF). METHODS: This trial was a prospective multicenter study of 58 T2DM patients with stable HF at five institutions in Japan. Patients who had been taking at least one antidiabetic drugs other than SGLT2 inhibitors started the administration of 5 mg/day of dapagliflozin. The physical examinations, blood tests, and echocardiography were performed at baseline and 6 months after administration of dapagliflozin. The primary endpoint was defined as a change in mitral inflow E and mitral e' annular velocities (E/e') between baseline and 6 months after the administration of dapagliflozin. The secondary end points consisted of a change in brain natriuretic peptide (BNP), LV mass index (LVMI) and left atrial volume index (LAVI). RESULTS: E/e' significantly decreased from 9.3 to 8.5 cm/s (p = 0.020) 6 months after administration of dapagliflozin. LAVI and LVMI significantly decreased from 31 to 26 mL/m2 (p = 0.001), and from 75.0 to 67.0 g/m2 (p < 0.001), respectively, 6 months after administration of dapagliflozin. No significant change was observed in BNP (from 27.9 to 28.9 pg/mL; p = 0.132) 6 months after administration of dapagliflozin, except for a significant decrease from 168.8 to 114.3 pg/mL (p = 0.012) in patients with BNP ≥ 100 pg/mL. CONCLUSION: This prospective multicenter trial showed the beneficial effect of SGLT2 inhibitors on LV diastolic functional parameters for T2DM patients with HF. Our findings may thus offer a new insight into the management of T2DM patients. Trial registration UMIN000019789, Registered 28 September 2014, Date of registration: 11/14/2015, Date of enrolment of the first participant to the trial: 6/15/2016, Date of enrolment of the last participant to the trial: 12/9/2017.Oct. 2018, Cardiovascular diabetology, 17(1) (1), 132 - 132, English, International magazine[Refereed]Scientific journal
- Oct. 2018, Pulm Circ, 8(4) (4), 2045894018781537, EnglishThe optimization of iloprost inhalation under moderate flow of oxygen therapy in severe pulmonary arterial hypertension[Refereed]Scientific journal
- BACKGROUND: Our aim was to investigate the baseline clinical and echocardiographic parameters for predicting left ventricular (LV) dysfunction after anthracycline chemotherapy and heart failure (HF) hospitalization in a single cancer disease. Methods and Results: We studied 73 patients with malignant lymphoma and preserved LV ejection fraction (LVEF). Echocardiography was performed before and after anthracycline chemotherapy. Global longitudinal strain (GLS) was determined from 3 standard apical views. LV dysfunction after anthracycline chemotherapy was defined according to the current definition of cancer therapeutics-related cardiac dysfunction. Long-term (50-month) unfavorable outcome was prespecified as hospitalization for HF. A total of 10 patients had LV dysfunction after anthracycline chemotherapy. Multivariate logistic regression analysis showed that baseline GLS was the only independent predictor of this dysfunction. Receiver-operating characteristic curve analysis identified the optimal GLS cutoff for predicting LV dysfunction after anthracycline chemotherapy as ≤19% (P=0.008). Furthermore, the Kaplan-Meier curve indicated that fewer patients with GLS >19% were hospitalized for HF than among those with GLS ≤19% (log-rank P=0.02). For sequential logistic models, a model based on baseline clinical variables (χ2=2.9) was improved by the addition of baseline LVEF (χ2=9.0; P=0.01), and further improved by the addition of baseline GLS (χ2=13.1, P=0.04). CONCLUSIONS: Watchful observation or early therapeutic intervention with established cardioprotective medications may be necessary for patients with malignant lymphoma and preserved LVEF but with abnormal GLS.Sep. 2018, Circulation journal : official journal of the Japanese Circulation Society, 82(10) (10), 2566 - 2574, English, Domestic magazine[Refereed]Scientific journal
- Sep. 2018, Journal of echocardiography, 16(3) (3), 150 - 151, English, Domestic magazine[Refereed]Scientific journal
- An 86-year-old man was admitted our hospital because of sudden onset of dyspnea after blunt chest trauma. Because his oxygen saturation deteriorated from 92% in the supine position to 86% in the sitting position, platypnea-orthodeoxia syndrome was suspected. Transesophageal echocardiography showed severe tricuspid regurgitation (TR) caused by anterior papillary muscle rupture. Furthermore, right-to-left shunt with TR through a patent foramen ovale (PFO) was observed. The diagnosis was therefore platypnea-orthodeoxia syndrome with right-to-left shunt through PFO with shunting exacerbated by acute severe TR after blunt chest trauma. The patient underwent urgent tricuspid valve repair and PFO closure and has remained asymptomatic postoperatively.Aug. 2018, The Canadian journal of cardiology, 34(8) (8), 1088.e11-1088.e13, English, International magazine[Refereed]Scientific journal
- Jul. 2018, J Atheroscler Thromb, 25(7) (7), 557 - 565, EnglishFuture Perspectives for Management of Stage A Heart Failure[Refereed]Scientific journal
- BACKGROUND: The purpose of this study was to investigate associations between right ventricular (RV) function and left ventricular (LV) diastolic function in patients with reduced LV ejection fraction (LVEF) and preserved LVEF. METHODS: A total of 139 patients who had undergone echocardiography were recruited. LV diastolic function was determined as the ratio of mitral inflow E to mitral e' lateral annular velocities (E/e'). RV function was determined as the RV index of myocardial performance (RIMP). Patients were divided into two groups: the preserved LVEF group (n = 100, LVEF ≥ 50%) and the reduced LVEF group (n = 39, LVEF < 50%). RESULTS: Associations between RV function and LV diastolic function in patients with reduced LVEF and preserved LVEF differed significantly. RIMP correlated significantly with E/e' in patients with reduced LVEF (r = 0.47, p = 0.003), but not in those with preserved LVEF (r = 0.04, p = 0.68). An important finding of the multivariate regression analysis showed that RIMP was the only independent determinant of E/e' in patients with reduced LVEF, whereas age and gender (not RIMP) was the independent determinant of E/e' in patients with preserved LVEF. CONCLUSIONS: Associations between RV function and LV diastolic function in patients with reduced LVEF and preserved LVEF differed significantly, and RV function showed a close correlation with LV diastolic function in patients with reduced LVEF, but not in those with preserved LVEF. Thus, these findings may well have clinical implications for better management of patients with reduced LVEF.Jun. 2018, Journal of echocardiography, 16(2) (2), 81 - 86, English, Domestic magazine[Refereed]Scientific journal
- BACKGROUND: The leg-positive pressure maneuver can safely and noninvasively apply preload stress without increase in total body fluid volume. The purpose of this study was to determine whether preload stress could be useful for risk stratification of patients with heart failure with reduced ejection fraction. METHODS AND RESULTS: For this study, 120 consecutive patients with heart failure with reduced ejection fraction were prospectively recruited. The stroke work index was estimated as product of stroke volume index and mean blood pressure, and the E/e' ratio was calculated to estimate ventricular filling pressure. The echocardiographic parameters were obtained both at rest and during leg-positive pressure stress. During the median follow-up period of 20 months, 30 patients developed adverse cardiovascular events. During preload stress, stroke work index increased significantly (from 3280±1371 to 3857±1581 mm Hg·mL/m2; P<0.001) along with minimal changes in ventricular filling pressure (E/e', from 16±10 to 17±9; P<0.05) in patients without cardiovascular events. However, patients with cardiovascular events showed impairment of Frank-Starling mechanism (stroke work index, from 2863±969 to 2903±1084 mm Hg·mL/m2; P=0.70) and a serious increase in E/e' ratio (from 19±11 to 25±14; P<0.001). Both the patients without contractile reserve and those without diastolic reserve exhibited worse event-free survival than the others (P<0.001). In a Cox proportional-hazards analysis, the changes in stroke work index (hazard ratio: 0.44 per 500 mm Hg·mL/m2 increase; P=0.001) and in E/e' (hazard ratio: 2.58 per 5-U increase; P<0.001) were predictors of cardiovascular events. CONCLUSION: Contractile reserve and diastolic reserve during leg-positive pressure stress are important determinants of cardiovascular outcomes for patients with heart failure with reduced ejection fraction.May 2018, Circulation. Cardiovascular imaging, 11(5) (5), e007160, English, International magazine[Refereed]Scientific journal
- Mar. 2018, Clin Anat, EnglishThe relationship between the membranous septum and the virtual basal ring of the aortic root in candidates for transcatheter aortic valve implantation[Refereed]Scientific journal
- Mar. 2018, Echocardiography, EnglishOptimal reconstruction of left ventricular outflow tract obstruction before surgical myectomy in a case with hypertrophic obstructive cardiomyopathy[Refereed]Scientific journal
- BACKGROUND: Visual estimation of left ventricular ejection fraction (LVEF) is widely applied to confirm quantitative EF. However, visual assessment is subjective, and variability may be influenced by observer experience. We hypothesized that a learning session might reduce the misclassification rate. METHODS: Protocol 1: Visual LVEFs for 30 cases were measured by 79 readers from 13 cardiovascular tertiary care centers. Readers were divided into 3 groups by their experience: limited (1-5 years, n=28), intermediate (6-11 years, n=26), and highly experienced (12-years, n=25). Protocol 2: All readers were randomized to assess the effect of a learning session with reference images only or feedback plus reference images. After the session, 20 new cases were shown to all readers following the same methodology. To assess the concordance and accuracy pre- and post-intervention, each visual LVEF measurement was compared to overall average values as a reference. RESULTS: Experience affected the concordance in visual EF values among the readers. Groups with intermediate and high experience showed significantly better mean difference (MD), standard deviation (SD), and coefficient of variation (CV) than those with limited experience at baseline. The learning session with reference image reduced the MD, SD, and CV in readers with limited experience. The learning session with reference images plus feedback also reduced proportional bias. Importantly, the misclassification rate for mid-range EF cases was reduced regardless of experience. CONCLUSION: This large multicenter study suggested that a simple learning session with reference images can successfully reduce the misclassification rate for LVEF assessment.Feb. 2018, J Cardiol, 72(1) (1), 74 - 80, English, International magazine[Refereed]Scientific journal
- OBJECTIVES: The closure of atrial septal defect (ASD) results in normalized left ventricular (LV) and right ventricular (RV) geometry, and can increase LV stroke volume (LVSV), but the parameters associated with this increase after the closure of ASD remain uncertain. METHODS: Seventy ASD patients, who underwent transcatheter closure, were studied. Their mean age was 57.80 ± 16.88 years, 42 (60%) were female, and LV ejection fraction (LVEF) was 66.76% ± 7.91% (all ≥55%). Transthoracic echocardiography was performed before and 3 months after the procedure. Global longitudinal strain (GLS) was determined as the average peak speckle tracking strain of 18 segments from the 3 standard apical views, LV dispersion was defined as standard deviation of time-to-peak strain from the same views, and RV systolic function was calculated by averaging the 3-regional peak speckle tracking longitudinal strains from the RV free wall. A significant relative increase in LVSV between before and 3 months after the closure was defined as ∆LVSV ≥15%. Twenty age-, gender-, and LVEF-matched controls served as the control group. RESULTS: Global longitudinal strain (GLS) and RV free wall strain were similar for ASD patients and controls, but LV dispersion in ASD patients was significantly larger. Global longitudinal strain (GLS) remained unchanged after transcatheter closure, whereas RV free wall strain and LV dispersion decreased significantly. An important finding of the multivariate logistic regression analysis showed that ∆LV dispersion was the only independent determinant of increased LVSV after the closure (OR 1.023; 95% CI 1.001-1.046; P < .01). CONCLUSIONS: The assessment of LV dispersion may well have clinical implications for better management of ASD patients after transcatheter closure.Feb. 2018, Echocardiography (Mount Kisco, N.Y.), 35(2) (2), 218 - 226, English, International magazine[Refereed]Scientific journal
- Feb. 2018, Echocardiography, EnglishComparison between characteristics of severe and very severe aortic stenosis[Refereed]Scientific journal
- W.B. Saunders Ltd, 2018, Respiratory Medicine Case Reports, 23, 55 - 59, English[Refereed]Scientific journal
- This case report is about an 85-year-old woman with bicuspid aortic stenosis (AS). Although preoperative multimodality imaging showed challenging anatomical aspects, transcatheter aortic valve replacement (TAVR) was selected to be performed as a less invasive alternative treatment approach, owing to her comorbidity. Postoperative transesophageal echocardiography and multidetector-row computed tomography revealed the presence of "locked-in leaflet" caused by stent distortion due to pinching by calcified native leaflets, with nodular calcification preventing the full expansion of the valve, which resulted in moderate perivalvular leakage. This is the first reported case of bicuspid AS treated with TAVR that eventually resulted in "locked-in leaflet."Jan. 2018, Echocardiography (Mount Kisco, N.Y.), 35(1) (1), 110 - 113, English, International magazine[Refereed]Scientific journal
- Antiphospholipid syndrome (APS) is a cause of chronic thromboembolic pulmonary hypertension (CTEPH) and it is associated with an increased risk of postoperative neurological complications. We experienced a case of reversible parkinsonism after pulmonary endarterectomy (PEA) and subsequent multiple cerebral infarctions under standard anticoagulation therapy in a patient with CTEPH associated with APS. Strict management using a combination of antiplatelet and anticoagulation therapy should be considered in patients with a high titer of triple antiphospholipid antibodies in the perioperative period. We should be aware of the high risk of postoperative neurologic manifestations in patients with APS.Jan. 2018, Intern Med, 57(14) (14), 2019 - 2023, English, Domestic magazine[Refereed]Scientific journal
- The patient was a 19-year-old woman who was diagnosed with patent ductus arteriosus complicating Eisenmenger syndrome at a previous medical institution. She was referred to our hospital and arranged for lung transplantation. She developed hemoptysis after the introduction of i.v. epoprostenol, which was administered as a bridging treatment while the patient awaited lung transplantation. She continued to suffer from recurrent hemoptysis, even after switching from i.v. epoprostenol to i.v. treprostinil. Angiography of the systemic and pulmonary arteries revealed the vessel responsible for the recurrent hemoptysis and pulmonary artery embolization was successfully performed. It is essential to identify the culprit vessel and physicians must not hesitate in performing embolization when patients develop lethal hemoptysis.Dec. 2017, Internal medicine (Tokyo, Japan), 56(24) (24), 3299 - 3304, English, Domestic magazine[Refereed]Scientific journal
- Dec. 2017, Int J Cardiovasc Imaging, 33(12) (12), 1905 - 1914, EnglishImpact of left ventricular longitudinal functional mechanics on the progression of diastolic function in diabetes mellitus[Refereed]Scientific journal
- Elsevier B.V., Dec. 2017, Journal of Arrhythmia, 33(6) (6), 646 - 648, English[Refereed]Scientific journal
- BACKGROUND: Although aortic valve intervention is recommended for virtually all symptomatic patients with aortic stenosis (AS), how urgently the intervention should be performed remains controversial. The aim of this study was thus to determine whether the preload reserve in response to leg-positive pressure (LPP) maneuver could serve for decision-making for AS patients awaiting aortic valve intervention.Methods and Results:Sixty-eight patients with symptomatic AS, who were referred for aortic valve intervention, were recruited. Stroke volume (SV) was assessed by means of pulsed-wave Doppler, and the ratio between transmitral E wave and mitral annular velocity (e') was calculated to estimate ventricular filling pressure. While waiting for intervention, 11 patients experienced preoperative cardiac events. During acute preload stress, forward SV for patients without cardiac events increased significantly (from 43±9 to 49±10 mL/m2, P<0.01) along with a minimal change in filling pressure (E/e': from 20±8 to 21±9, NS). For patients with cardiac events, the Frank-Starling mechanism was significantly impaired (SVi: from 40±9 to 38±7 mL/m2, NS), while filling pressure increased to the critical level (E/e': from 24±8 to 31±8, P<0.001). Both the patients without flow reserve (∆SVi <4.5 mL/m2) and those without diastolic reserve (∆E/e' ≥2.9) exhibited significantly worse event-free survival than the others (P<0.05, respectively). CONCLUSIONS: Assessment of preload reserve during LPP stress could facilitate risk stratification of patients with severe AS waiting for aortic valve intervention.Nov. 2017, Circulation journal : official journal of the Japanese Circulation Society, 81(12) (12), 1927 - 1935, English, Domestic magazine[Refereed]Scientific journal
- Nov. 2017, JOURNAL OF CARDIOVASCULAR COMPUTED TOMOGRAPHY, 11(6) (6), 499 - 500, English[Refereed]Scientific journal
- Nov. 2017, ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES, 34(11) (11), 1721 - 1724, English[Refereed]Scientific journal
- Nov. 2017, Cardiovasc Diabetol, 16(1) (1), 145, EnglishImpact of overweight on left ventricular function in type 2 diabetes mellitus[Refereed]Scientific journal
- Nov. 2017, ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES, 34(11) (11), 1717 - 1720, English[Refereed]Scientific journal
- Although right ventricular (RV) pacing is the only effective treatment for patients with symptomatic bradycardia, it creates left ventricular (LV) dyssynchrony, which can induce LV dysfunction and heart failure. The current criterion for consideration of cardiac resynchronization therapy (CRT) is LV ejection fraction (LVEF) ≤ 35%, but indication for CRT in patients required for RV pacing with LVEF > 35% remains unclear.We studied 40 patients, all LVEF ≥ 35%, who had undergone implantable cardioverter-defibrillator implantation with RV pacing < 5%. Echocardiography was performed at baseline and during RV pacing. LV dyssynchrony was defined as anteroseptal-to-posterior wall delay from the mid-LV short-axis view using two-dimensional speckle-tracking radial strain (significant: ≥ 130 ms). Patients were divided into two groups based on baseline LVEF: normal LVEF ( ≥ 50%; n = 20) and mildly reduced LVEF (35-50%; n = 20).LVEF and LV dyssynchrony in patients with mildly reduced LVEF deteriorated significantly during RV pacing compared to those in patients with normal LVEF. Moreover, changes in LV dyssynchrony during RV pacing significantly correlated with changes in LVEF (r = -0.44, P < 0.01). Multivariate logistic regression analysis showed that baseline LVEF was the only independent predictor and baseline LVEF < 48% predictive of significant LV dyssynchrony during RV pacing.The extent of RV pacing-induced LV dysfunction may be associated with baseline LV function. These adverse effects on patients with mildly reduced LVEF of 35-50% and indications for RV pacing due to bradycardia can thus be prevented by CRT.Oct. 2017, International heart journal, 58(5) (5), 724 - 730, English, Domestic magazine[Refereed]Scientific journal
- Sep. 2017, JOURNAL OF CARDIOPULMONARY REHABILITATION AND PREVENTION, 37(5) (5), 341 - 346, English[Refereed]Scientific journal
- Jul. 2017, ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES, 34(7) (7), 1073 - 1076, English[Refereed]Scientific journal
- Mar. 2017, Int J Cardiovasc Imaging, 33(3) (3), 313 - 321, EnglishRight ventricular relative wall thickness as a predictor of outcomes and of right ventricular reverse remodeling for patients with pulmonary hypertension[Refereed]Scientific journal
- Mar. 2017, PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 40(3) (3), 301 - 309, English[Refereed]Scientific journal
- 2017, Intern Med, 56(2) (2), 163 - 168, EnglishAn Isolated Case of Late-onset Amyloidogenic Transthyretin Type Familial Amyloid Polyneuropathy Associated with a Mutant Transthyretin Substituting Methionine for Valine at Position 30 Showing Latent Progressive Cardiac Involvement Confirmed by Serial Ann[Refereed]Scientific journal
- 2017, INTERNAL MEDICINE, 56(16) (16), 2155 - 2158, English[Refereed]Scientific journal
- Significant prognostic impact of improvement in ventriculo-arterial coupling induced by dobutamine stress on cardiovascular outcome for patients with dilated cardiomyopathy.AIMS: The purpose of this study was to investigate the prognostic impact of the changes in ventriculo-arterial (VA) coupling during dobutamine stress on the cardiovascular events for patients with dilated cardiomyopathy (DCM). METHODS AND RESULTS: For this study, 89 DCM patients with ejection fractions of 32 ± 10% and 30 normal controls were recruited. Ees was estimated with the non-invasive single-beat method using three-dimensional echocardiography at rest and during dobutamine stress (20 μg/kg/min). Effective arterial elastance (Ea) was calculated as left ventricular (LV) end-systolic pressure divided by stroke volume, and VA coupling was calculated as Ea/Ees. Event-free survival was then tracked for 32 months. At baseline, VA coupling was far from optimal in patients with DCM compared with controls (Ea/Ees: 2.49 ± 1.02 vs. 1.04 ± 0.21, P < 0.001). During the follow-up period, 22 patients developed adverse cardiovascular events. During dobutamine stress, VA coupling was significantly improved in patients without cardiovascular events (from 2.47 ± 1.09 to 1.59 ± 0.68, P < 0.001), but remained unchanged in those with cardiovascular events. A multivariate Cox proportional-hazards analysis revealed that age, NYHA functional class (>II), and the change in VA coupling during dobutamine stress were the independent determinants of cardiovascular events (P < 0.05, <0.01, and <0.001, respectively). When patients were divided into two subgroups based on the finding of receiver operating characteristic curve analysis, patients with good VA coupling reserve (cut-off: change in VA coupling> 0.29) showed significantly favourable event-free survival than those with poor VA coupling reserve (P < 0.001). CONCLUSIONS: Improvement in VA coupling during dobutamine stress is an important determinant of cardiovascular outcome for patients with DCM.Nov. 2016, European heart journal cardiovascular Imaging, 17(11) (11), 1296 - 1304, English, International magazine[Refereed]Scientific journal
- Nov. 2016, Sci Rep, 6, 36749, English2-Aminobutyric acid modulates glutathione homeostasis in the myocardium[Refereed]Scientific journal
- Japanese College of Cardiology (Nippon-Sinzobyo-Gakkai), Oct. 2016, Journal of Cardiology, 68(4) (4), 308 - 315, English[Refereed]Scientific journal
- BACKGROUND: Right ventricular (RV) systolic function is one of the most important determinants of outcome for pulmonary hypertension (PH) patients, but the factors influencing prognosis vary widely. Elevated right atrial (RA) pressure is reported to be one of these prognostic factors, but its functional importance has scarcely been assessed. METHODS: Eighty-two PH patients, all of whom underwent echocardiography and right heart catheterization, were recruited. RV function was assessed by two-dimensional speckle tracking longitudinal strain from RV-focused apical four-chamber view and calculated by averaging the three regional peak strains from the RV free wall (RV-free). RA function was determined as the sum of three peak strain values comprising reservoir, conduit, and contractile function (sum of RA strain). RESULTS: Sum of RA strain correlated significantly with hemodynamic parameters such as mean right atrial pressure (r = -0.35, P = 0.002) and end-diastolic RV pressure (r = -0.29, P = 0.008). Patients with sum of RA strain ≥30.2% experienced more favorable outcomes than those with sum of RA strain <30.2% (log-rank P = 0.001). Furthermore, patients with impaired RV systolic function (RV-free <20%) and RA function (sum of RA strain <30.2%) showed the worst outcome (P = 0.001). A sequential Cox model based on clinical variables (χ(2) = 5.8) was improved by addition of RV-free (χ(2) = 8.7; P < 0.05) and further improved by addition of sum of RA strain (χ(2) = 12.0; P < 0.01). CONCLUSION: Right atrial strain appears to be a valuable additive factor for predicting outcomes for PH patients, and comprehensive functional assessment of right-sided heart using speckle tracking strain may have potential clinical implications for better management of PH patients.Jul. 2016, Echocardiography (Mount Kisco, N.Y.), 33(7) (7), 1001 - 8, English, International magazine[Refereed]Scientific journal
- Mar. 2016, Eur Heart J Cardiovasc Imaging, 17(3) (3), 334 - 42, EnglishLeft ventricular dyssynergy and dispersion as determinant factors of fatal ventricular arrhythmias in patients with mildly reduced ejection fraction[Refereed]Scientific journal
- Feb. 2016, Echocardiography, 33(2) (2), 207 - 15, EnglishAssociation of Apical Longitudinal Rotation with Right Ventricular Performance in Patients with Pulmonary Hypertension: Insights into Overestimation of Tricuspid Annular Plane Systolic Excursion[Refereed]Scientific journal
- 2016, INTERNAL MEDICINE, 55(22) (22), 3279 - 3283, English[Refereed]Scientific journal
- Jan. 2016, Echocardiography, 33(1) (1), 23 - 9, EnglishUtility of Isovolumic Contraction Peak Velocity for Evaluation of Adult Patient Status after Transcatheter Closure of Atrial Septal Defect[Refereed]Scientific journal
- Dec. 2015, Echocardiography, 32(12) (12), 1889 - 90, EnglishSevere Aortic Regurgitation Caused by Unicuspid Aortic Valve Based on Quadricuspid Aortic Valve[Refereed]Scientific journal
- Nov. 2015, Echocardiography (Mount Kisco, N.Y.), 32(11) (11), 1743 - 1743, English, International magazine[Refereed]Scientific journal
- Nov. 2015, Eur Heart J Cardiovasc Imaging, 16(11) (11), 1213 - 23, EnglishBi-ventricular contractile reserve offers an incremental prognostic value for patients with dilated cardiomyopathy[Refereed]Scientific journal
- Sep. 2015, J Cardiol, 66(3) (3), 212 - 7, EnglishCombining passive leg-lifting with transmural myocardial strain profile for enhanced predictive capability for subclinical left ventricular dysfunction in Duchenne muscular dystrophy[Refereed]Scientific journal
- Aug. 2015, J Arrhythm, 31(4) (4), 221 - 5, EnglishThe effectiveness of cardiac resynchronization therapy for patients with New York Heart Association class IV non-ambulatory heart failure[Refereed]Scientific journal
- Jun. 2015, Bone Marrow Transplantation, 50(6) (6), 870 - 872, English[Refereed]Scientific journal
- BACKGROUND: Identification of heart failure (HF) symptoms in patients with severe aortic stenosis (AS) and preserved left ventricular (LV) ejection fraction (EF) is clinically important, but assessment of HF symptoms is challenging. It was recently reported that resting left atrium (LA) functions are related to exercise performance and are also important prognostic markers for patients with HF. The aim of this study was to assess the association of the HF symptoms with LA function in patients with severe AS and preserved LVEF. METHODS: We retrospectively studied 40 patients with severe AS and preserved LVEF (all ≥50%) who were referred for aortic valve replacement (AVR). LA reservoir (SR-LAs), conduit (SR-LAe), and booster-pump (SR-LAa) functions were determined as the averaged global LA speckle tracking longitudinal strain rate from apical four- and two-chamber views. Twenty patients were symptomatic and 20 asymptomatic. RESULTS: Aortic stenosis severity was similar for the 2 groups. Symptomatic status was associated with age, LV mass index, hemoglobin, B-type natriuretic peptide, LV end-systolic volume index, LVEF, LA volume index, SR-LAs, SR-LAe, and SR-LAa. Importantly, multivariate logistic regression analysis revealed that SR-LAa was the only independent determinant of symptomatic status (OR = 0.242, P = 0.002). Furthermore, significant improvement of SR-LAa was observed along with the reduction in LA volume index and LV mass index after AVR. CONCLUSIONS: SR-LAa was found to be associated with the HF symptoms. Characterization of LA booster-pump function may be useful for the assessment of the symptomatic status in patients with severe AS patients and limited physical activity.May 2015, Echocardiography (Mount Kisco, N.Y.), 32(5) (5), 758 - 67, English, International magazine[Refereed]Scientific journal
- May 2015, European heart journal cardiovascular Imaging, 16(5) (5), 572 - 572, English, International magazine[Refereed]Scientific journal
- May 2015, Cardiovasc Diabetol, 14, 47, EnglishAssociation of peripheral nerve conduction in diabetic neuropathy with subclinical left ventricular systolic dysfunction[Refereed]Scientific journal
- Although impaired right ventricular (RV) performance has been associated with adverse outcomes for pulmonary hypertension (PH) patients, the relationship between bi-ventricular interdependence and outcomes is not yet fully understood. We studied 96 PH patients. RV systolic function was assessed by means of RV free-wall longitudinal speckle-tracking strain (RV-free), and left ventricular (LV) filling as early diastolic transmitral flow velocity (TMF-E). RV-free ≤19 % and TMF-E <60 cm/s were adopted as pre-defined cut-offs for RV systolic dysfunction and LV under-filling, respectively, associated with worse outcomes. Long-term outcome was tracked over 2.2 years. RV-free correlated significantly with TMF-E (r = 0.57, p < 0.001).TMF-E and RV-free were significantly lower in patients with than in those without cardiac events. RV systolic dysfunction and LV under-filling was observed in 35 patients. These features were associated with worse long-term survival compared to other sub-groups (log-rank p = 0.012). A sequential Cox model based on clinical variables including world health organization functional class IV and brain natriuretic peptide >150 pg/dl (χ(2) = 1.2) was improved by the addition of RV-free (χ(2) = 5.5, p = 0.04) as well as of TMF-E (χ(2) = 11.5, p = 0.01). In conclusions, RV systolic function was shown to correlate significantly with LV filling in PH patients. In addition, not only assessment of RV systolic function, but also of a combined bi-ventricular parameter comprising RV systolic function and LV filling may well have clinical implications for more successful management of PH patients.Apr. 2015, The international journal of cardiovascular imaging, 31(4) (4), 691 - 8, English, International magazine[Refereed]Scientific journal
- Apr. 2015, Can J Cardiol, 31(4) (4), 529 - 36, EnglishRight Ventricular Function and Right-Heart Echocardiographic Response to Therapy Predict Long-term Outcome in Patients With Pulmonary Hypertension[Refereed]Scientific journal
- Apr. 2015, Cardiovasc Diabetol, 14, 37, EnglishClinical features of subclinical left ventricular systolic dysfunction in patients with diabetes mellitus[Refereed]Scientific journal
- Feb. 2015, Eur Heart J, 36(8) (8), 471, EnglishInfective endarteritis associated with aortic dissection underlying bacterial meningitis[Refereed]Scientific journal
- 2015, Int Heart J, 56(5) (5), 516 - 21, EnglishImpact of Right Ventricular Geometry on Mitral Regurgitation After Transcatheter Closure of Atrial Septal Defect[Refereed]Scientific journal
- Dec. 2014, Int J Cardiovasc Imaging, 30(8) (8), 1473 - 81, EnglishGlobal endocardial area change rate for the assessment of left ventricular relaxation and filling pressure: using 3-dimensional speckle-tracking study[Refereed]Scientific journal
- Oct. 2014, Int J Cardiovasc Imaging, 30(7) (7), 1269 - 77, EnglishUtility of combining assessment of right ventricular function and right atrial remodeling as a prognostic factor for patients with pulmonary hypertension[Refereed]Scientific journal
- Oct. 2014, Int J Cardiovasc Imaging, 30(7) (7), 1279 - 87, EnglishEvaluation of global circumferential strain as prognostic marker after administration of β-blockers for dilated cardiomyopathy[Refereed]Scientific journal
- Aug. 2014, Echocardiography, 31(7) (7), 848 - 57, EnglishLeft Ventricular Endocardial Dysfunction in Patients with Preserved Ejection Fraction after Receiving Anthracycline[Refereed]Scientific journal
- May 2014, Pacing Clin Electrophysiol, 37(5) (5), 576 - 84, EnglishDiscrepancy between Electrical and Mechanical Dyssynchrony in Patients with Heart Failure and an Electrical Disturbance[Refereed]Scientific journal
- Apr. 2014, J Am Soc Echocardiogr, 27(4) (4), 430 - 439, EnglishPreliminary Observations of Prognostic Value of Left Atrial Functional Reserve during Dobutamine Infusion in Patients with Dilated Cardiomyopathy[Refereed]Scientific journal
- Apr. 2014, Echocardiography, 31(4) (4), 464 - 73, EnglishCombined baseline strain dyssynchrony index and its acute reduction predicts mid-term left ventricular reverse remodeling and long-term outcome after cardiac resynchronization therapy[Refereed]Scientific journal
- Mar. 2014, Heart Vessels, 29(2) (2), 282 - 5, EnglishSubsequent shunt closure after targeted medical therapy can be an effective strategy for secundum atrial septal defect with severe pulmonary arterial hypertension: two case reports : Strategy for ASD with Severe PAH[Refereed]Scientific journal
- Feb. 2014, Int J Cardiovasc Imaging, 30(2) (2), 295 - 304, EnglishLeft atrial booster-pump function as a predictive parameter for new-onset postoperative atrial fibrillation in patients with severe aortic stenosis[Refereed]Scientific journal
- 2014, Circ J, 78(9) (9), 2250 - 8, EnglishEasy-to-use comprehensive speckle-tracking approach for cardiac resynchronization therapy[Refereed]Scientific journal
- Jun. 2013, J Cardiovasc Transl Res, 6(3) (3), 425 - 9, EnglishFurther deterioration of LV ejection fraction and mechanical synchrony during RV apical pacing in patients with heart failure and LBBB[Refereed]Scientific journal
- May 2013, Hypertension, 61(5) (5), 1002 - 7, EnglishEndothelial lipase modulates pressure overload-induced heart failure through alternative pathway for Fatty Acid uptake[Refereed]Scientific journal
- AIMS: It remains difficult to detect subtle left ventricular (LV) myocardial dysfunction in chronic aortic regurgitation (AR) patients with the preserved ejection fraction (EF). METHODS AND RESULTS: We studied 36 chronic severe AR patients undergoing surgical correction with the EF of 58 ± 6% (all ≥ 50%). Echocardiography was performed before and 12 ± 8 months after surgical correction. We used two-dimensional speckle-tracking strain imaging to evaluate global radial strain in the inner-half (GRSinner), outer-half (GRSouter), and total (GRStotal) layer from the mid-LV short-axis view. We also evaluated the transmural strain profile in the LV posterior wall by using myocardial tissue Doppler radial strain, and the location of peak strain was determined as the percentage of the distance from the endocardium to the epicardium accounted for by the wall thickness. Fifteen EF-matched normal volunteers were studied for comparison. GRSinner for AR patients was significantly smaller than that for controls (28.9 ± 12.9 vs. 37.1 ± 9.1%, P = 0.032), and the location of peak strain had significantly shifted to the epicardial side compared with that in controls (27.1 ± 14.0-13.2 ± 4.8%, P = 0.001). In contrast, GRStotal and GRSouter were similar for the two groups. After surgical correction, EF increased from 58 ± 6 to 62 ± 7% (P = 0.018), GRSinner from 27.8 ± 12.5 to 37.7 ± 14.6% (P < 0.0001), and the location of peak strain significantly shifted to the endocardial side (26.9 ± 13.9-19.1 ± 11.9%, P = 0.028). However, GRStotal and GRSouter did not change. CONCLUSION: The LV endocardium side, impaired in chronic AR patients with the preserved EF, improved after surgical correction. Our observations may prove useful for evaluating subtle early changes in such patients.Apr. 2013, European heart journal cardiovascular Imaging, 14(4) (4), 339 - 46, English, International magazine[Refereed]Scientific journal
- Myocardial damage in Duchenne muscular dystrophy (DMD) has lethal outcomes, making early detection of myocardial changes in patients with DMD vital, because early treatment can help prevent the development of myocardial fibrosis. The aim of the present study was, therefore, to test the hypothesis that transmural strain profile (TMSP) analysis can predict future left ventricular (LV) dysfunction in patients with DMD with preserved ejection fraction. We studied 82 consecutive patients with DMD without LV wall motion abnormality, with an ejection fraction of 60 ± 5% (all ≥55%) and age 11 ± 3 years. Echocardiography was performed at baseline and 1 year of follow-up. TMSP in the posterior wall was evaluated from the mid-LV short-axis view. A normal TMSP pattern (1 peak in the endocardium, group 1) was seen in 44 patients, and TMSP with a notch (2 peaks in the endocardium, group 2) in the remaining 38 (46%). Wall motion abnormality in the posterior wall was observed in 16 patients (42%) in group 2 at 1 year of follow-up but in none of the patients in group 1 (42% vs 0%; p <0.001). Importantly, multivariate analysis showed that only TMSP with a notch (odds ratios 1.524, p <0.001) was an independent determinant of the presence of LV posterior wall motion abnormality at 1 year of follow-up. In conclusion, subclinical LV dysfunction can be detected by evaluation of TMSP in patients with DMD who do not have wall motion abnormalities by conventional echocardiography. TMSP with a notch proved effective for evaluating subtle early changes in patients with DMD and might be useful for predicting LV dysfunction.Mar. 2013, The American journal of cardiology, 111(6) (6), 902 - 7, English, International magazine[Refereed]Scientific journal
- Feb. 2013, Echocardiography, 30(2) (2), 147 - 54, EnglishImpact of preserved myocardial contractile function in the segments attached to the papillary muscles on reduction in functional mitral regurgitation[Refereed]Scientific journal
- Since cardiac sarcoidosis (CS) leads to substantial morbidity and sudden death, early diagnosis and appropriate management are crucial for patients with CS. Echocardiography used to be considered a useful diagnostic tool for patients with CS, but CS may clinically present as dilated cardiomyopathy (DCM). Our objective was to investigate whether a novel three-dimensional (3-D) speckle-tracking strain can identify patients with CS more accurately. We studied 23 CS patients with an ejection fraction (EF) of 46 ± 10 %, and 16 EF-matched patients with DCM (EF 45 ± 11 %). Global radial (GRS), circumferential (GCS) and longitudinal (GLS) strain was assessed using 3-D speckle-tracking system. GRS of patients with CS was significantly lower than that of patients with DCM (18.5 ± 8.4 vs. 28.5 ± 8.3 %, p < 0.01), but GCS and GLS in patients with CS and DCM were similar. GRS ≦ 21.1 could differentiate CS from DCM with a sensitivity of 70 %, specificity of 88 % and area under the curve of 0.79. An additional noteworthy findings was that, patients with CS showed more negative radial strain curves than did those with DCM (1.7 ± 2.3 vs. 0.1 ± 0.5, p < 0.01). In conclusion, 3-D speckle-tracking radial strain shows good potential to distinguish CS from DCM. Our observations can thus be expected to have clinical implications for management of CS patients.Feb. 2013, The international journal of cardiovascular imaging, 29(2) (2), 317 - 24, English, International magazine[Refereed]Scientific journal
- 2013, Internal Medicine, 52(24) (24), 2771 - 2775, English[Refereed]Scientific journal
- 2013, Circ J, 77(9) (9), 2383 - 9, EnglishNoninvasive and simple assessment of cardiac output and pulmonary vascular resistance with whole-body impedance cardiography is useful for monitoring patients with pulmonary hypertension[Refereed]Scientific journal
- 2013, Intern Med, 52(1) (1), 71 - 4, EnglishIsolated primary cardiac sarcoidosis presenting as acute heart failure[Refereed]Scientific journal
- 2013, Intern Med, 52(21) (21), 2473, EnglishAortic and mitral regurgitation associated with Behçet's disease[Refereed]Scientific journal
- 2013, Circulation Journal, 77(3) (3), 756 - 763, English[Refereed]Scientific journal
- Dynamic left ventricular dyssynchrony assessed on 3-dimensional speckle-tracking area strain during dobutamine stress has a negative impact on cardiovascular events in patients with idiopathic dilated cardiomyopathy.BACKGROUND: Left ventricular (LV) dyssynchrony is not a stable phenomenon, but rather, changes dynamically. Given that the prognostic impact of dynamic dyssynchrony has not yet been elucidated, the objective was to investigate the clinical impact of dynamic dyssynchrony on patients with dilated cardiomyopathy (DCM). METHODS AND RESULTS: Seventy DCM patients with ejection fraction 32±9% were retrospectively recruited, and 3-dimensional speckle-tracking area strain was used to measure both contractile reserve and changes in dyssynchrony during dobutamine stress. The standard deviation of time-to-peak area strain was adopted as the systolic dyssynchrony index. Event-free survival was then tracked over a 13-month period. A ≥7.55% increase in systolic dyssynchrony index during dobutamine stress (Δsystolic dyssynchrony index) was the best predictor of cardiovascular events with 77% sensitivity and 88% specificity. Multivariate Cox analysis indicated that not only the absence of contractile reserve (Δglobal area strain ≤21.1%: hazard ratio [HR], 15.29; P=0.01), but the presence of dynamic dyssynchrony (ΔLV dyssynchrony ≥7.55%: HR: 7.591; P=0.003) was an independent predictor of cardiovascular events. Importantly, absence of dynamic dyssynchrony and presence of contractile reserve were associated with the most favorable outcome (98%), whereas the reverse condition was associated with the worst outcome (20%, P<0.001). CONCLUSIONS: Dynamic dyssynchrony is a potential predictor of cardiovascular events in patients with DCM, while assessment of dynamic dyssynchrony in combination with contractile reserve may further improve prognostic risk stratification.2013, Circulation journal : official journal of the Japanese Circulation Society, 77(7) (7), 1750 - 9, English, Domestic magazine[Refereed]Scientific journal
- Dec. 2012, Am J Cardiol, 110(12) (12), 1814 - 9, EnglishUtility of combined assessment of baseline dyssynchrony and its acute improvement to predict long-term outcomes after cardiac resynchronization therapy[Refereed]Scientific journal
- Dec. 2012, J Am Soc Echocardiogr, 25(12) (12), 1299 - 308, EnglishContractile reserve assessed by three-dimensional global circumferential strain as a predictor of cardiovascular events in patients with idiopathic dilated cardiomyopathy[Refereed]Scientific journal
- Nov. 2012, JOURNAL OF CARDIOPULMONARY REHABILITATION AND PREVENTION, 32(6) (6), 379 - 385, English[Refereed]Scientific journal
- Nov. 2012, Eur Heart J, 33(21) (21), 2680 - 91, EnglishThe relationship of QRS morphology and mechanical dyssynchrony to long-term outcome following cardiac resynchronization therapy[Refereed]Scientific journal
- Nov. 2012, Echocardiography, 29(10) (10), 1201 - 10, EnglishRegional Heterogeneity of Systolic Dysfunction Is Associated with Ventricular Dyssynchrony in Patients with Idiopathic Dilated Cardiomyopathy and Narrow QRS Complex[Refereed]Scientific journal
- Nov. 2012, J Cardiopulm Rehabil Prev, 32(6) (6), 379 - 85, EnglishDifferences in hemodynamic parameters and exercise capacity between patients with pulmonary arterial hypertension and chronic heart failure[Refereed]Scientific journal
- Oct. 2012, Eur Heart J Cardiovasc Imaging, 13(10) (10), 849 - 56, EnglishMultidirectional left ventricular performance detected with three-dimensional speckle-tracking strain in patients with chronic right ventricular pacing and preserved ejection fraction[Refereed]Scientific journal
- Aug. 2012, 日本心臓病学会誌, 7(Suppl.I) (Suppl.I), 155, Japanese循環器疾患と交感神経系 左室同期不全が慢性心不全患者の心臓交感神経活性に及ぼす影響と心臓再同期療法の効果予測について[Refereed]Scientific journal
- Jul. 2012, Can J Cardiol, 28(4) (4), 515, EnglishSuccessful steroid therapy for heart failure due to myocarditis associated with primary biliary cirrhosis[Refereed]Scientific journal
- Jul. 2012, J Am Soc Echocardiogr, 25(7) (7), 726 - 32, EnglishSubclinical myocardial dysfunction in patients with reverse-remodeled dilated cardiomyopathy[Refereed]Scientific journal
- Jun. 2012, European Association of Echocardiography, 13(6) (6), 531, EnglishMultiple regions of coarctation of the aorta associated with bicuspid aortic valve in a 74-year-old female[Refereed]Scientific journal
- Apr. 2012, 超音波医学, 39(Suppl.) (Suppl.), S526, Japanese多発性の大動脈縮窄症を合併した大動脈二尖弁の一例Research society
- Apr. 2012, 超音波医学, 39(Suppl.) (Suppl.), S383, Japanese心臓再同期療法前と施行急性期における左室同期不全の指標を用いた長期予後予測の検討Research society
- Apr. 2012, 超音波医学, 39(Suppl.) (Suppl.), S366, Japanese左室駆出率が保たれたアントラサイクリン系薬剤使用症例における左室心内膜機能障害[Refereed]Scientific journal
- Apr. 2012, The American journal of cardiology, 109(8) (8), 1187 - 93, EnglishRelation Between Strain Dyssynchrony Index Determined by Comprehensive Assessment Using Speckle-Tracking Imaging and Long-Term Outcome After Cardiac Resynchronization Therapy for Patients With Heart FailureScientific journal
- Apr. 2012, The American journal of cardiology, 109(8) (8), 1197 - 205, EnglishLeft Ventricular Dyssynchrony Using Three-Dimensional Speckle-Tracking Imaging as a Determinant of Torsional Mechanics in Patients With Idiopathic Dilated Cardiomyopathy[Refereed]Scientific journal
- Apr. 2012, Echocardiography (Mount Kisco, NY), 29(4) (4), 411 - 8, EnglishEfficacy of Longitudinal Speckle Tracking Strain in Conjunction with Isometric Handgrip Stress Test for Detection of Ischemic Myocardial Segments[Refereed]Scientific journal
- Apr. 2012, 超音波医学, 39(Suppl.) (Suppl.), S368, JapaneseDuchenne型筋ジストロフィーにおける機能的僧帽弁逆流と左房径の関係についてResearch society
- 2012, Circulation journal, 76(2) (2), 382 - 9, EnglishEffect of left ventricular dyssynchrony on cardiac sympathetic activity in heart failure patients with wide QRS duration[Refereed]Scientific journal
- Impact of left ventricular afterload on longitudinal dyssynchrony in patients with severe aortic stenosis and preserved ejection fraction.BACKGROUND: The purpose of this study was to investigate whether patients with severe aortic stenosis (AS) and preserved ejection fraction (EF) have dyssynchrony and whether it improves after aortic valve replacement (AVR). METHODS AND RESULTS: We studied 30 consecutive patients with severe AS and preserved EF undergoing AVR. For baseline comparison, we studied 17 EF-matched patients with mild-to-moderate AS, and 18 EF-matched normal volunteers. Longitudinal dyssynchrony was determined as the standard deviation for time-to-peak speckle-tracking strain in apical 4- and 2-chamber views at the basal- and mid-levels. Radial and circumferential dyssynchrony was determined as the difference for time-to-peak strain between the anteroseptum and posterior wall from the mid-left ventricular (LV) short-axis view. Each of the myocardial functions was also evaluated by averaging each peak systolic strain. Longitudinal dyssynchrony and function in patients with severe AS was significantly worse than in the patients with mild-to-moderate AS and the controls (94 ± 46 vs. 66 ± 18 ms* and 52 ± 17 ms*, and 12.5 ± 3.7% vs. 16 ± 3.5%* and 18.7 ± 3.7%*, respectively, *P<0.05, vs. severe AS). In contrast, radial and circumferential dyssynchrony were similar for the 3 groups. Importantly, the dyssynchrony of patients with severe AS significantly improved after AVR from 94 ± 46 ms to 68 ± 22 ms (P<0.005). CONCLUSIONS: Significant longitudinal dyssynchrony was present in patients with severe AS and preserved EF, and it improved after AVR.2012, Circulation journal : official journal of the Japanese Circulation Society, 76(3) (3), 744 - 51, English, Domestic magazine[Refereed]Scientific journal
- Tissue Doppler imaging-derived myocardial acceleration during isovolumetric contraction predicts pulmonary capillary wedge pressure in patients with reduced ejection fraction.BACKGROUND: Tissue Doppler imaging-obtained isovolumetric myocardial acceleration (IVA) is load independent, reportedly predicts systolic functions, and correlates with exercise capacity in patients with reduced ejection fraction (EF). We hypothesized that IVA correlates with the pulmonary capillary wedge pressure (PCWP) in patients with reduced EF. METHODS AND RESULTS: Of 113 patients, correlations between PCWP and IVA were done for all patients, 48 patients with EF ≥55%, and 65 patients with EF <55%. Results were compared to the correlation between PCWP and other echocardiographic predictors. IVA correlated moderately with PCWP in all patients (r=0.54, P<0.0001) and was comparable to the E/A and E/e' ratios. In patients with EF ≥55%, IVA lost correlation and the only predictor was the E/e' ratio (r=0.08, 0.58, P=0.58, <0.0001). In patients with EF <55%, IVA was better than E/A and E/e' (r=0.72, 0.61, 0.51, P<0.0001), especially for atrial fibrillation or when E/e' fell between 8 and 15. Furthermore, IVA >1.60 m/s(2) can predict PCWP ≥15 mmHg, with a sensitivity of 95%, specificity of 73%, and an area under the curve of 0.867 (P<0.0001). CONCLUSIONS: IVA can predict PCWP in patients with reduced EF, and can be considered an alternative to the E/e' ratio for patients with atrial fibrillation or E/e' ratio between 8 and 15.2012, Circulation journal : official journal of the Japanese Circulation Society, 76(6) (6), 1399 - 408, English, Domestic magazine[Refereed]Scientific journal
- Dec. 2011, Rev Esp Cardiol, 64(12) (12), 1082 - 9, English[Are new myocardial tracking systems of three-dimensional strain a reality in daily clinical practice?][Refereed]Scientific journal
- Nov. 2011, The American journal of cardiology, Vol. 108, No. 9, pp. 1327-34, EnglishRelation between left ventricular morphology and reduction in functional mitral regurgitation by cardiac resynchronization therapy in patients with idiopathic dilated cardiomyopathy[Refereed]Scientific journal
- Oct. 2011, Journal of the American Society of Echocardiography, Vol. 24, No. 10, pp. 1101-8, EnglishUtility of right ventricular free wall speckle-tracking strain for evaluation of right ventricular performance in patients with pulmonary hypertension[Refereed]Scientific journal
- Oct. 2011, European journal of echocardiography, Vol. 12, No. 10, pp. 782-9, EnglishReverse remodelling induces progressive ventricular resynchronization after cardiac resynchronization therapy 'from vicious to virtuous cycle'Scientific journal
- Sep. 2011, J Am Coll Cardiol, 58(14) (14), 1401 - 13, EnglishEchocardiographic assessment of myocardial strain[Refereed]Scientific journal
- Sep. 2011, Echocardiography (Mount Kisco, NY), Vol. 28, No. 8, pp. E172-3, EnglishA case of unicommissural unicuspid aortic valve stenosis diagnosed by real time three-dimensional transesophageal echocardiographyScientific journal
- May 2011, JACC Cardiovasc Imaging, 4(5) (5), 445 - 56, EnglishLeft ventricular mechanical dyssynchrony in acute onset cardiomyopathy: association of its resolution with improvements in ventricular function[Refereed]Scientific journal
- Apr. 2011, Cardiovascular ultrasound, Vol. 9, No. , pp. 11-11, EnglishStrain dyssynchrony index determined by three-dimensional speckle area tracking can predict response to cardiac resynchronization therapy[Refereed]Scientific journal
- Apr. 2011, Eur J Echocardiogr, 12(4) (4), 283 - 90, EnglishComparison of mitral valve area by pressure half-time and proximal isovelocity surface area method in patients with mitral stenosis: effect of net atrioventricular compliance.Scientific journal
- Mar. 2011, Am J Physiol Heart Circ Physiol, 300(3) (3), H853 - 8, EnglishLeft ventricular systolic torsion correlates global cardiac performance during dyssynchrony and cardiac resynchronization therapy[Refereed]Scientific journal
- Feb. 2011, Cardiovascular ultrasound, Vol. 9, No. 1, pp. 4-4, EnglishExercise-induced left bundle branch block and subsequent mechanical left ventricular dyssynchrony -resolved with pharmacological therapy[Refereed]Scientific journal
- Jan. 2011, EUROPEAN HEART JOURNAL, 32(1) (1), 93 - 103, English[Refereed]Scientific journal
- Dec. 2010, Eur Heart J, 31(24) (24), 3054 - 62, EnglishAssociation of intraventricular mechanical dyssynchrony with response to cardiac resynchronization therapy in heart failure patients with a narrow QRS complex[Refereed]Scientific journal
- Nov. 2010, Circulation, 122(19) (19), 1910 - 8, EnglishRelationship of echocardiographic dyssynchrony to long-term survival after cardiac resynchronization therapy[Refereed]Scientific journal
- Jul. 2010, Eur Heart J, 31(14) (14), 1690 - 700, EnglishDyssynchrony by speckle-tracking echocardiography and response to cardiac resynchronization therapy: results of the Speckle Tracking and Resynchronization (STAR) study[Refereed]Scientific journal
- Jun. 2010, Heart Rhythm, 7(6) (6), 813 - 9, EnglishDynamic and site-specific impact of ventricular pacing on left ventricular ejection fraction[Refereed]Scientific journal
- May 2010, JACC Cardiovasc Imaging, 3(5) (5), 461 - 71, EnglishComparative mechanical activation mapping of RV pacing to LBBB by 2D and 3D speckle tracking and association with response to resynchronization therapy[Refereed]Scientific journal
- Mar. 2010, CIRCULATION-CARDIOVASCULAR IMAGING, 3(2) (2), 134 - 141, English[Refereed]Scientific journal
- Feb. 2010, JACC Cardiovasc Imaging, 3(2) (2), 132 - 40, EnglishUsefulness of echocardiographic dyssynchrony in patients with borderline QRS duration to assist with selection for cardiac resynchronization therapy[Refereed]Scientific journal
- Jan. 2010, Am J Cardiol, 105(2) (2), 235 - 42, EnglishUsefulness of three-dimensional speckle tracking strain to quantify dyssynchrony and the site of latest mechanical activation[Refereed]Scientific journal
- Jun. 2009, J Am Soc Echocardiogr, 22(6) (6), 677 - 84, EnglishPrediction of response to cardiac resynchronization therapy by speckle tracking echocardiography using different software approaches[Refereed]Scientific journal
- Dec. 2008, J Am Soc Echocardiogr, 21(12) (12), 1382 - 8, EnglishEchocardiographic speckle tracking radial strain imaging to assess ventricular dyssynchrony in a pacing model of resynchronization therapy[Refereed]Scientific journal
- Apr. 2007, Circulation Journal, 71(4) (4), 517 - 23, EnglishRelationship between regional and global left ventricular systolic and diastolic function in patients with coronary artery disease assessed by strain rate imaging[Refereed]Scientific journal
- Jun. 2006, JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 19(6) (6), 756 - 762, EnglishScientific journal
- Jan. 2018, Heart Fail Rev, EnglishPotential impact of SGLT2 inhibitors on left ventricular diastolic function in patients with diabetes mellitus[Refereed]Introduction scientific journal
- Sep. 2016, Int J Cardiovasc Imaging, 32(9) (9), 1357 - 1361, EnglishVery early stage left ventricular endocardial dysfunction of patients with hypereosinophilic syndrome[Refereed]Report scientific journal
- Springer-Verlag Tokyo, 01 Jun. 2016, Journal of Echocardiography, 14(2) (2), 53 - 60, English[Refereed]Book review
- Jan. 2015, 心エコー, 16(1号) (1号), 24 - 31, Japanese【新しいAHA/ACC弁膜症ガイドラインを知る-心エコーの役割は変わったのか】 大動脈弁逆流Introduction commerce magazine
- Jun. 2014, 内科, 113(6号) (6号), 1220 - 1222, Japanese【内科疾患 最新の治療 明日への指針】(第4章)循環器 肥大型心筋症Introduction commerce magazine
- Jun. 2014, 内科, 113(6号) (6号), 1223 - 1224, Japanese【内科疾患 最新の治療 明日への指針】(第4章)循環器 二次性心筋症Introduction commerce magazine
- Jun. 2014, 内科, 113(6号) (6号), 1217 - 1219, Japanese【内科疾患 最新の治療 明日への指針】(第4章)循環器 拡張型心筋症Introduction commerce magazine
- Mar. 2014, 心エコー, 15(3号) (3号), 250 - 259, Japanese【Integrated Imagingのすすめ-心エコー・血管造影・CT・MRI・核医学はどのような使われ方をしているのか】 心筋症Introduction commerce magazine
- A case was 53-year-old female with dilated-phase hypertrophic cardiomyopathy. She was classified as New York Heart Association functional class III heart failure despite receiving optimal medical therapy. The electrocardiogram taken showed intraventricular conduction delay with a QRS width of 194 msec. The left ventricular (LV) end-diastolic and systolic volumes, and ejection fraction (EF) were 101 mL, 68 mL, and 32%, respectively. The patient showed no significant mechanical LV dyssynchrony as evidenced by two-dimensional (2D) speckle tracking radial strain, which is defined as the time difference between anterior-septum and posterior wall, of 105 msec (<130 msec). Three-dimensional (3D) speckle tracking radial strain was performed for more detailed LV mechanical dyssynchrony analysis. An especially important finding for 3D speckle tracking radial strain analysis was that the average time-to-peak strain of 5 septum segments at 3 different LV levels (basal-anterior-septum, basal-septum, mid-anterior-septum, mid-septum, apical-septum) was significantly shorter than that of 5 posterolateral segments at 3 different LV levels (basal-posterior, basal-lateral, mid-posterior, mid-lateral, apical-lateral). This time difference between septum and posterolateral wall was 216 msec (204 msec vs. 420 msec), which was considered to indicate significant LV mechanical dyssynchrony (≥130 msec). 12 months after cardiac resynchronization therapy (CRT), EF had improved to 47%, while end-systolic and diastolic volumes had decreased to 88 mL and 47 mL, respectively, so that the patient was classified as a responder. In conclusions, a newly developed 3D speckle tracking strain can provide a comprehensive evaluation of "true" LV mechanical dyssynchrony from pyramidal 3D data sets acquired in the same beat, thus yielding more accurate information than previously possible with the 2D speckle tracking system.Oct. 2013, Echocardiography (Mount Kisco, N.Y.), 30(9) (9), E292-5 - 5, English, International magazine
- Jan. 2013, 超音波医学, 40(1号) (1号), 69, Japanese古典的Ehlers-Danlos症候群に合併した高度僧帽弁閉鎖不全症の1例Meeting report
- Jan. 2013, 超音波医学, 40(1号) (1号), 72, Japanese拡張型心筋症様病態を合併したベーチェット病の一例Meeting report
- Jan. 2013, 超音波医学, 40(1号) (1号), 71, Japanese右房原発血管肉腫の1例Meeting report
- Aug. 2012, 日本心臓病学会誌, 7(Suppl.I) (Suppl.I), 313, Japanese肺動脈性高血圧症患者の長期予後予測における右室自由壁スペックルトラッキング法の有用性Meeting report
- Aug. 2012, 日本心臓病学会誌, 7(Suppl.I) (Suppl.I), 193, Japanese心エコー 手術適応をビジュアルに決める 重症大動脈弁閉鎖不全症に対する手術適応の検討と手術術式の決定における経食道心エコー図検査の役割Meeting report
- Others, 文光堂, 2018, Japaneseがん患者の心臓を守る!腫瘍循環器学Q&A / 化学療法薬の心毒性に対する予防法があれば教えてくださいScholarly book
- Others, 文光堂, Dec. 2017, JapaneseMedical Practice / ガイドラインに基づいた三尖弁逆流の治療Scholarly book
- Others, 文光堂, Oct. 2017, Japanese月間心エコー / 3D経食道エコーの役割 症例編Scholarly book
- Others, 医学図書出版, Feb. 2017, JapaneseICUとCCU / 急性肺血栓塞栓症を疑う患者におけるPOCUSGeneral book
- Others, 文光堂, 2017, Japanese非薬物療法で心不全をコントロールして癒す / 非薬物療法で心不全をコントロールして癒すScholarly book
- Others, 東京医学社, 2017, Japanese成人病と生活習慣病 / アミロイドーシスScholarly book
- Others, 文光堂, Nov. 2016, Japanese月刊心エコー / ドプラ法における匠の技 “応用編 ドプラ法を駆使した臨床診断 右心機能評価におけるドプラ法活用法指南General book
- Others, 文光堂, Sep. 2016, Japanese月間心エコー / Game-changing echocardiography治療の流れを変える心エコー検査“不整脈疾患におけるGame-changing echocardiography 心臓腫瘍”General book
- Others, 医学出版, Aug. 2016, Japanese月間糖尿病 / 糖尿病性神経障害の特殊な病型、病態 糖尿病性神経障害と左室機能障害General book
- Others, 南江堂, Apr. 2016, Japanese月間心エコー / ここまでは、ここからは“人工弁の「ここまでは」の見極めどころ”General book
- Others, 南江堂, Mar. 2016, Japanese循環器疾患 最新の治療 2016-2017 / 心膜疾患、腫瘍(心臓腫瘍)General book
- Others, 日本心臓財団, 2016, Japanese心臓 / 大動脈弁狭窄と逆流、“治療方針を決める大動脈弁逆流の心エコー”General book
- Others, 南山堂, 2016, Japaneseエキスパートが現場で明かす 心不全診療の極意 / 拡張不全に対する治療について Question:薬は効くの?Scholarly book
- Others, Medical View, 2016, JapaneseIntegrated Cardiac Imaging / 画像で病態に迫る、治療効果を判定する、“大動脈閉鎖不全症”General book
- Others, 南江堂, Oct. 2015, Japanese月間心エコー / 心筋症 up-to-date 2015 “二次性心筋症を逃さない 教えて!心エコー診断のポイント 心アミロイドーシス ”General book
- Others, 医学書院, Jun. 2015, Japanese臨床検査 / 日常検査としての心エコー “右心機能評価”General book
- Others, 南江堂, May 2015, Japanese月刊心エコー / 疾患ごとの評価項目マニュアル化“大動脈弁逆流”General book
- Others, 南江堂, Jan. 2015, Japanese月間心エコー / 新しくなったAHA/ACC弁膜症ガイドラインを読み解く“大動脈弁逆流”General book
- Others, 文光堂, Aug. 2014, Japanese月間心エコー / 心臓のカタチ“心膜液貯留×低収縮”General book
- Others, 文光堂, Mar. 2014, Japanese月間心エコー / 心エコー・血管造影・CT・MRI・核医学はどのような使われ方をしているのか“心筋症”General book
- Others, 南江堂, 2014, Japanese臨床雑誌 内科 / 循環器(肥大型心筋症)General book
- Others, 南江堂, 2014, Japanese臨床雑誌 内科 / 循環器(二次性型心筋症)General book
- Others, 南江堂, 2014, Japanese臨床雑誌 内科 / 循環器(拡張型心筋症)General book
- Others, 南江堂, 2014, Japanese循環器疾患 最新の治療 2014-2015 / 心膜疾患、腫瘍(心内血栓)General book
- Others, 文光堂, Dec. 2013, Japanese月間心エコー / ルーチン検査における右心機能評価General book
- Others, 文光堂, Sep. 2013, Japanese月間心エコー / これでわかる!FMRのエコーレポートはココを読め!General book
- Others, 文光堂, Mar. 2013, Japanese月間心エコー / 全身性疾患に合併する心疾患 膠原病と心疾患General book
- Others, 文光堂, Jul. 2012, Japanese月間心エコー / 大動脈弁閉鎖不全症をどう評価すべきか?General book
- Others, 文光堂, 2012, Japanese新・心臓病診療プラクティス / 画像検査で見つかる疾患と形態異常(Marfan症候群などの結合織異常)General book
- Others, 文光堂, Jan. 2012, Japanese月間心エコー / 手術適応を決める心エコーのツボ大動脈弁逆流:全てAHA/ACCガイドライン通りの手術適応でよいかGeneral book
- Others, 文光堂, Nov. 2011, Japanese月間心エコー / 肺塞栓症の超音波診断General book
- Others, 文光堂, Jul. 2011, Japanese月間心エコー / 収縮期雑音General book
- Others, 文光堂, Feb. 2011, Japanese月間心エコー / 肺塞栓症は急性と慢性で違うかOthers
- Others, 文光堂, 2011, Japanese新・心臓病診療プラクチティス / 大動脈弁閉鎖不全症をきたす疾患とそのみかたGeneral book
- Others, MEDICAL VIEW, 2011, Japanese今さら聞けない心エコー図 / 今さら聞けない特別な検査法(携帯型心エコーはどのような症例に有効ですか?またその限界は?)General book
- Others, MEDICAL VIEW, 2011, Japanese今さら聞けない心エコー図 / 今さら聞けない心エコー所見の読み方・書き方(肝静脈血流波形からなにがわかりますか?)General book
- Others, MEDICAL VIEW, 2011, Japanese今さら聞けない心エコー図 / 今さら聞けない計測法(右室径はどこを測定すればよいですか?)General book
- Others, MEDICAL EYE, Sep. 2010, JapaneseRad Fan / Speckle Tracking Strainを臨床でどのように利用するか?─左室Dyssynchronyの評価への応用-General book
- Others, 最新医学社, 2010, Japanese最新医学 / 狭心症の診断:心エコーOthers
- 第83回日本循環器学会学術集会, Mar. 2019, English, 横浜, Domestic conferenceImpact of Glycemic Variability on Left Ventricular Diastolic Function in Type 2 Diabetes MellitusOral presentation
- The 68th Annual Scientific Session of the American College of Cardiology, Mar. 2019, English, New Orleans, International conferenceImpact of Glycemic Variability on Left Ventricular Diastolic Function in Type 2 Diabetes MellitusPoster presentation
- 第83回日本循環器学会学術集会, Mar. 2019, Japanese, 横浜, Domestic conferenceImpact of Dapagliflozin on Left Ventricular Diastolic Function of Patients with Type 2 Diabetic Mellitus with Chronic Heart FailureOral presentation
- The 68th Annual Scientific Session of the American College of Cardiology, Mar. 2019, English, New Orleans, International conferenceEffect of Dapagliflozin on Left Ventricular Diastolic Function of Patients with Type 2 Diabetic Mellitus with Chronic Heart FailurePoster presentation
- The 68th Annual Scientific Session of the American College of Cardiology, Mar. 2019, English, New Orleans, International conferenceComprehensive Simplified Left Atrial Assessment for Predicting Recurrence of Atrial Fibrillation Following Pulmonary Vein Isolation in Patients with Paroxysmal Atrial FibrillationPoster presentation
- 第83回日本循環器学会学術集会, Mar. 2019, Japanese, 横浜, Domestic conferenceComprehensive Simplified Left Atrial Approach for Predicting Recurrence of Atrial Fibrillation Following Pulmonary Vein Isolation in Patients with Atrial FibrillationPoster presentation
- 第83回日本循環器学会学術集会, Mar. 2019, Japanese, 横浜, Domestic conferenceAssociation of Tricuspid Regurgitation with Long-Term Outcome in Patients with Pulmonary HypertensionPoster presentation
- The 68th Annual Scientific Session of the American College of Cardiology, Mar. 2019, English, New Orleans, International conferenceAssociation of Tricuspid Regurgitation with Long-Term Outcome in Patients with Pulmonary HypertensionPoster presentation
- The 68th Annual Scientific Session of the American College of Cardiology, Mar. 2019, English, New Orleans, International conferenceAssociation of Body Fat Mass with Left Ventricular Myocardial Systolic Longitudinal Dysfunction in Type 2 Diabetes MellitusPoster presentation
- The 68th Annual Scientific Session of the American College of Cardiology, Mar. 2019, English, New Orleans, International conferenceA Case of Sudden Onset of Platypnea-Orthodeoxia Syndrome Caused by Traumatic Tricuspid Regurgitation with Ruptured Chordae Tendineae After Blunt Chest TraumaPoster presentation
- 第47回人工心臓と補助循環懇話会学術集会, Feb. 2019, Japanese, 佐賀, 症例は 47 歳女性。20 歳代より労作時呼吸困難を自覚し、39 歳時分娩 中に急性左心不全を発症した。心エコーにて左室拡大を伴うびまん性左 室収縮能低下を認め、拡張型心筋症と考え内服加療を開始したが心機能 の改善を認めず、41 歳時に機能性僧帽弁閉鎖不全症に対して、僧帽弁置 換術および三尖弁輪形成術を施行した。また持続性心室頻拍に対して、 同年 ICD 植込み術を施行した。45 歳時より NYHAⅢ-Ⅳの状態が続き、 BNP 1000-1500pg/mL と高値で推移した。46 歳時に精査加療目的で入院後、 強心剤依存の状態となり、心臓移植適応登録後、同年 11 月植込型左室 補助人工心臓(LVAD)装着術を施行した。術直後は良好な循環動態であっ たが、術後 1 日目より心電図波形が著明な低電位となり、心室頻拍(VT) が出現した。電気的除細動に加, Domestic conference拡張型心筋症に対して植え込み型左室補助人工心臓装着術後、難治性心室頻拍と右心不全加療に難渋した一例Poster presentation
- 第47回人工心臓と補助循環懇話会学術集会, Feb. 2019, Japanese, 佐賀, Domestic conference拡張型心筋症に対して左室補助人工心臓装着後、微小なくも膜下出血を繰り返し認めた一例Poster presentation
- 第126回日本循環器学会近畿地方会, Nov. 2018, Japanese, 大阪, Domestic conference二次孔欠損型心房中隔欠損に合併する下大静脈欠損の診断を契機に判明した左側相同の一例Oral presentation
- 第126回日本循環器学会 近畿地方会, Nov. 2018, Japanese, 大阪, Domestic conference僧帽弁機械弁置換術,Maze 術後の僧帽弁輪を旋回する心房頻拍に冠静脈洞内での通電が有効であった一例Oral presentation
- 第1回日本腫瘍循環器学会学術集会, Nov. 2018, Japanese, 東京, Domestic conferenceType 2 CTRCDの発生予測におけるトロポニンIとGLSの有用性についてOral presentation
- The 45th Annual Scientific Meeting of the Korean Society of Echocardiography, Nov. 2018, English, Seoul, International conferenceShortened Posterior Mitral Leaflet in Patients with Atrial Fibrillation and Significant Mitral Regurgitation[Invited]Invited oral presentation
- 日本超音波医学会 第45 回関西地方会学術集会, Oct. 2018, Japanese, 神戸, Domestic conference疣腫を見誤った一例Oral presentation
- 日本超音波医学会 第45 回関西地方会学術集会, Oct. 2018, Japanese, 神戸, Domestic conference経カテーテル的心房中隔閉鎖術が奏功した超高齢者重症心不全の一例Oral presentation
- 日本超音波医学会 第45 回関西地方会学術集会, Oct. 2018, Japanese, 神戸, Domestic conference運動負荷エコー図の意義、適応、禁忌[Invited]Nominated symposium
- 第22回心不全学会学術集会, Oct. 2018, Japanese, 東京, Domestic conferenceTherapeutic Strategy and Predicting Prognosis in Patients of Fulminant Myocarditis with Mechanical Circulatory SupportOral presentation
- The 9th Asian Pacific Congress of Heart Failure, Oct. 2018, English, 東京, International conferenceImpact of Left Ventricular Longitudinal Myocardial Function on the Progression of DM-Related Cardiac Dysfunction[Invited]Invited oral presentation
- 第66回日本心臓病学会学術集会, Sep. 2018, Japanese, 大阪, Domestic conference可逆性の右室壁肥厚を呈した右室優位の心サルコイドーシスの一例Invited oral presentation
- 第66回日本心臓病学会学術集会, Sep. 2018, Japanese, 大阪, Domestic conference右心機能はどれくらい重要か? 何で診るか?[Invited]Nominated symposium
- 日本内科学会 第221回近畿地方会, Sep. 2018, Japanese, 大阪, Domestic conference悪性関節リウマチの急性期に発作性心房細動・洞不全症候群・僧帽弁逆流症の一過性増悪を認め、ステロイド投与にて改善が得られた1例Oral presentation
- 第66回日本心臓病学会学術集会, Sep. 2018, Japanese, 大阪, Domestic conferenceストレインの臨床応用-利点と問題点-[Invited]Nominated symposium
- European Society of Cardiology Congress 2018, Sep. 2018, English, Munich, International conferenceIntegrated assessment of aortic valve resistance using multi-detector computed tomography and echocardiography reflects aortic valvular burden and has prognostic value in patients with aortic stenosisPoster presentation
- 第66回日本心臓病学会学術集会, Sep. 2018, English, 大阪, Domestic conferenceAssociation of Relatively Shortened Posterior Mitral Leaflet with Mitral Regurgitation in Atrial FibrillationOral presentation
- European Society of Cardiology Congress 2018, Aug. 2018, English, Munich, International conferenceNon-invasive assessment of preload reserve using the leg-positive pressure manoeuvre in patients with repaired tetralogy of FallotPoster presentation
- 第126回 日本循環器学会近畿地方会, Jun. 2018, Japanese, 大阪, Domestic conference不整脈および左室収縮機能障害を合併した、抗ミトコンドリアM2抗体陽性筋炎の1例Oral presentation
- 日本超音波医学会 第91回学術集会, Jun. 2018, Japanese, 日本超音波医学会, 神戸, 右室収縮能は様々な心疾患において予後規定因子であると報告されている。特に、肺高血圧症患者では、右室収縮機能の低下は、独立した予後規定因子であることが多数の研究結果から証明されている。2009年にESC/ERSから公表された肺高血圧症の診断と治療に関するガイドラインでは、肺高血圧症(肺動脈性肺高血圧症)のリスク評価で推奨されている心エコー図指標は、心膜液の有無と三尖弁輪部収縮期移動距離(TAPSE)が記載されていた1。しかしながら、ESC/ERSから公表されている最新のガイドラインでは、肺高血圧症(肺動脈性肺高血圧症)のリスク評価で推奨されている心エコー図指標は、心膜液の有無と右房面積のみであり、右室収縮能に関する指標は他のモダリティーも含めて記載がない2。心エコー図法は優れた心機能評価法であるが、右室は左室と異なり形態が複雑であるため、回転楕円体と仮, Domestic conference肺高血圧症のガイドラインに物申すPublic symposium
- 日本超音波医学会 第91回学術集会, Jun. 2018, Japanese, 神戸, 【背景】肺高血圧症(PH)の予後には様々な因子が複雑に関与しており、その予測は単純ではない。近年、三尖弁閉鎖不全症(TR)が様々な心不全患者の予後予測に有用であり、独立した予後予測因子であると報告されている。しかしながら、TRとPH患者の予後との関連、さらにPH治療によるTRの変化がどのように予後と関連するのかは明らかではない。よって今回我々は、PH患者を対象にTRの重症度と予後との関連、ならびにPH治療によるTRの変化と予後との関連を評価した。, Domestic conference肺高血圧症における三尖弁閉鎖不全症と長期予後との関係Oral presentation
- 第125回日本循環器学会近畿地方会, Jun. 2018, Japanese, 大阪, Domestic conference肺高血圧症における三尖弁閉鎖不全症と長期予後との関係Oral presentation
- 日本超音波医学会 第91回学術集会, Jun. 2018, Japanese, 神戸, Domestic conference透析用シャントを閉鎖することで劇的な僧帽弁閉鎖不全症の改善が得られた一例Poster presentation
- 第126回 日本循環器学会近畿地方会, Jun. 2018, Japanese, 大阪, Domestic conference長期植込み後に心理的負担によってICD抜去に至った一例Oral presentation
- 第125回日本循環器学会近畿地方会, Jun. 2018, Japanese, 大阪, Domestic conference心房細動が僧帽弁形態に及ぼす影響と僧帽弁閉鎖不全症との関連についてOral presentation
- The 29th Annual Scientific Session of the American Society of Echocardiography, Jun. 2018, English, Nashville, International conferenceThe Emerging Role of 3D Speckle Tracking and RV Strain in Pulmonary Hypertension[Invited]Nominated symposium
- 日本超音波医学会 第91回学術集会, Jun. 2018, Japanese, 神戸, 心機能障害はないが、心不全発症の危険因子を有する場合は心不全のステージAに分類され、高血圧、糖尿病、メタボリックシンドローム、喫煙などを有する患者がこれに含まれる。ステージAは将来心不全を発症する最も早期の段階として捉えられており、この段階で、十分な対策が取られなければ、器質的な心臓疾患を発症し(ステージB)、症候性、また難治性の心不全へと移行していく(ステージC、D)。そのため、それぞれのステージで適切な治療を行うことが、病態の進行予防のためには重要であると考えられている。さらに、心不全は進行性の病態であるため、より早期での治療介入が望ましいと考えられている。しかしながら、ステージAの患者において、将来の心不全の発症ならびに構造的な心形態異常の出現を予測することは非常に困難である。よって、ステージAの段階での高血圧、糖尿病、メタボリックシンドローム, Domestic conferenceStage A心不全患者におけるストレイン法の役割Public symposium
- The 29th Annual Scientific Session of the American Society of Echocardiography, Jun. 2018, English, Nashville, International conferenceShortened Posterior Mitral Leaflet in Patients with Atrial Fibrillation and Significant Mitral RegurgitationPoster presentation
- The 29th Annual Scientific Session of the American Society of Echocardiography, Jun. 2018, English, Nashville, International conferenceAssociation of Tricuspid Regurgitation with Long-Term Outcome in Patients with Pulmonary HypertensionPoster presentation
- 日本心エコー図学会 第29回学術集会, Apr. 2018, Japanese, 日本心エコー図学会, 盛岡, 心肥大は心血管リスクを増大する独立因子であり、様々なタイプの心不全を発症する。また、心肥大の進行は心不全の悪化と関連していることも証明されている。心肥大を呈する最も一般的な病態は高血圧症であり、最も一般的な心筋症は肥大型心筋症である。よって心肥大の症例をみたら、高血圧症によるものなのか、肥大型心筋症であるのかを鑑別することがまず重要である。心肥大を呈する心筋症では、日常臨床では肥大型心筋症の他に、心アミロイドーシス、心サルコイドーシス、ミトコンドリア心筋症、心ファブリー病などを鑑別することが必要である。心肥大を最も簡便に評価できる画像診断法は心エコー図検査である。心エコー図検査では心肥大の程度のみならず、血行動態や心機能も同時に評価が可能である。また、Strain Imaging(特にGlobal Longitudinal Strain: GLS)を, Domestic conference肥大心をみたら・・・総論[Invited]Nominated symposium
- 日本心エコー図学会 第29回学術集会, Apr. 2018, Japanese, 盛岡, Domestic conference心房細動が僧帽弁形態に及ぼす影響と僧帽弁閉鎖不全症との関連についてOral presentation
- 日本心エコー図学会 第29回学術集会, Apr. 2018, Japanese, 盛岡, Domestic conference胸部打撲を契機に進行性に著明な低酸素血症を来した高齢男性の1例Poster presentation
- The 82nd Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2018, Japanese, The Japanese Circulation Society, 大阪, Background: The underlying mechanism of mitral regurgitation (MR) in atrial fibrillation (AF) is considered as isolated annulus dilation by left atrial (LA) remodeling. However, the association of mitral valve geometry with MR in AF patients remains uncle, Domestic conferenceShortened Posterior Mitral Leaflet in Patients with Atrial Fibrillation and Significant Mitral RegurgitationPoster presentation
- JCS2018, Mar. 2018, English, 日本循環器学会, 大阪, Domestic conferenceRelationship among Aortic Elongation, Tortuosity, and Configurations of the Aortic Root in Candidates for Transcatheter Aortic Valve ReplacementPoster presentation
- The 82nd Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2018, Japanese, The Japanese Circulation Society, 大阪, Diabetes mellitus (DM) is a major cause of heart failure (HF) with preserved ejection fraction (HFpEF) which is usually clinically presenting as left ventricular (LV) diastolic dysfunction. In addition, several studies of DM patients have identified LV diastolic dysfunction as the earliest functional alteration in the course of DM-related cardiac dysfunction, thus leading to it, Domestic conferenceImpact of Left Ventricular Longitudinal Myocardial Function on the Progression of Diastolic Function in Diabetes Mellitus[Invited]Nominated symposium
- JCS2018, Mar. 2018, English, 日本循環器学会, 大阪, Domestic conferenceImpact of Aortic Valve Calcification Burden and Distribution on Postprocedural Cardiac Conduction Disturbances following Transcatheter Aortic Valve ReplacementPoster presentation
- The 82nd Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2018, Japanese, The Japanese Circulation Society, 大阪, Background: Atrial fibrillation (AF) causes structural and electrical remodeling. Left atrial (LA) volume is a robust predictor for recurrence of AF after pulmonary vein isolation, however, recurrence of AF can be associated with multiple factors. Therefo, Domestic conferenceEchocardiography, Atrial FibrillationPoster presentation
- The 82nd Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2018, Japanese, The Japanese Circulation Society, 大阪, Background: Left ventricular (LV) longitudinal myocardial systolic dysfunction (LVSD) has been identified in type 2 diabetes mellitus (T2DM) patients, and it should be considered the first marker of a preclinical form of DM-related cardiac dysfunction. Ov, Domestic conferenceAssociation of Body Fat Mass with Left Ventricular Myocardial Systolic Longitudinal Dysfunction in Type 2 Diabetes MellitusOral presentation
- The 82nd Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2018, Japanese, The Japanese Circulation Society, 大阪, 2D speckle trackingによる右心機能評価の有用性を講演した, Domestic conference2D speckle trackingによる右心機能評価[Invited]Nominated symposium
- The 46th Annual Meeting for Artificial Heart and Assisted Circulation, Feb. 2018, Japanese, Research Conference for Artificial Heart and Assisted Circulation of Japan, 熱海, 当院の劇症型心筋炎症例より、治療戦略と今後の課題を検討した, Domestic conference当院の劇症型心筋炎症例より、治療戦略と今後の課題を検討するPoster presentation
- The 124th Kinki Regional Office of the Japanese Circulation Society, Nov. 2017, Japanese, The Japanese Circulation Society, 大阪, 動脈管開存と心房中隔欠損を合併した高度肺高血圧症の一成人例を発表した, Domestic conference動脈管開存と心房中隔欠損を合併した高度肺高血圧症の一成人例Oral presentation
- The 124th Kinki Regional Office of the Japanese Circulation Society, Nov. 2017, Japanese, The Japanese Circulation Society, 大阪, 症例は83歳女性。以前より大動脈弁狭窄症を指摘されていたが、一年前より合計3度の心不全入院を繰り返すようになり、精査加療目的で当院紹介となった。過去の心不全入院歴は高度大動脈弁狭窄症の経過として矛盾しないものの、大動脈弁位での圧較差に比して心エコー図での大動脈弁弁口面積および大動脈弁石灰化の程度は軽度であり、重症度に不一致を認めた。心臓CTによる任意多断面再構成(MPR)画像では、各交連部下に膜様組織の増生を認め、弁口部よりも左室流出路側に最狭窄部が存在していることが判明した。患者の全身状態から経カテーテル的大動脈弁置換術を施行し、その後心不全入院は消失した。弁交連部下の膜様組織による大動脈弁狭窄の様子を、心エコー図、心臓CT-MPR法にて同定しえたため画像とともに供覧する。, Domestic conference重症度の判別に苦慮した大動脈弁狭窄症の一例Oral presentation
- The 124th Kinki Regional Office of the Japanese Circulation Society, Nov. 2017, Japanese, The Japanese Circulation Society, 大阪, 【背景】TAFRO症候群は、Castleman病の類縁疾患明とし提案され、原因なく急性あるいは亜急性に、全身浮腫(胸腹水)、発熱、骨繊維症、肝脾腫(Thrombocytopenia、Anasasrca、Fevere、Reticuin fibrosis、Organomegaly)の5徴を特徴とする疾患である。2010年には本邦からCastleman病とは異なる独立した疾患単位であることが明らかになった。今回我々はTAFRO症候群に重症心不全を呈し、集学的治療が奏功した症例を経験したので報告する。【症例】17歳男性。インフルエンザ罹患後から持続する発熱、頸部および腋窩リンパ節腫大、胸背部痛ならびに腰痛のために近医を救急受診された。精査では炎症反応の上昇、造影CTでは少量の腹水、肝脾腫を認めた。感染のフォーカスは特定できなかったが、細菌感染が疑われ、抗生剤, Domestic conferenceA case of TAFRO syndrome with severely depressed left ventricular functionOral presentation
- The 124th Kinki Regional Office of the Japanese Circulation Society, Nov. 2017, Japanese, The Japanese Circulation Society, 大阪, 症例は85歳女性。Type 0の先天性大動脈二尖弁に基づく高度の大動脈弁狭窄症に対し経カテーテル的大動脈弁植え込み術(TAVI)を施行した。術前の画像検査にて楕円形の弁輪、ならびにそれと直交する線状の弁接合部と非対称性の弁尖石灰化を認めた。解剖学的懸念はあったものの、患者背景を考慮し低侵襲のTAVIを選択した。術後の経食道心エコー図及び心臓CTでは、弁尖の石灰化に挟まれ弁尖先端部でステントが歪曲し、一枚の弁尖の可動性が消失していた。また、弁輪部でも石灰化によりステント拡張が障害され、中等度の弁周囲逆流を認めた。幸い血行動態的影響は乏しく、外来にて慎重に経過観察することとした。今回先天性大動脈二尖弁の特徴的な形態により人工弁が十分に拡張せず、弁機能不全を呈した1例を経験したので報告する。, Domestic conference経カテーテル的大動脈弁植え込み術後に弁機能不全を呈した、先天性大動脈二尖弁の1例Oral presentation
- 第124回日本循環器学会近畿地方会, Nov. 2017, Japanese, 日本循環器学会, 大阪, Domestic conference急性増悪の経過をたどった悪性関節リウマチに伴う肺高血圧症の一例Oral presentation
- American Heart Association scientific session 2017, Nov. 2017, English, American Heart Association, Anaheim, CA, USA, 【Background】 Heart failure (HF) symptoms in severe aortic regurgitation (AR) often occur irrespective of AR severity and left ventricular ejection (LV) fraction (LVEF), and its precisely detection can be difficult. End-systolic ventricular elastance (Ees), International conferenceVentriculo-arterial Coupling to Detect Heart Failure Symptoms in Patients with Severe Aortic Regurgitation and Preserved Left Ventricular Ejection FractionPoster presentation
- American Heart Association scientific session 2017, Nov. 2017, English, American Heart Association, Anaheim, CA, USA, Background: Pulmonary hypertension (PH) is characterized by a marked and sustained elevation of pulmonary vascular resistance, leading to an increase in pulmonary artery pressure, and right ventricular (RV) failure. RV pressure overload in PH patients can, International conferenceVentricular Interdependence by Means of Preload Stress Echocardiography in Patients with Pulmonary HypertensionPoster presentation
- American Heart Association scientific session 2017, Nov. 2017, English, American Heart Association, Anaheim, CA, USA, Background: Atrial fibrillation (AF) causes structural and electrical remodeling, including atrial enlargement and fibrosis. Left atrial (LA) volume is a robust predictor for recurrence of AF after pulmonary vein isolation, however, recurrence of AF can b, International conferenceComprehensive Assessment of Left Atrium for Predicting Recurrence of Atrial Fibrillation Following Pulmonary Vein Isolation in Patients with Paroxysmal Atrial FibrillationPoster presentation
- The 124th Kinki Regional Office of the Japanese Circulation Society, Nov. 2017, Japanese, The Japanese Circulation Society, 大阪, 【背景】糖尿病では左室長軸方向の収縮能低下が左室拡張能障害よりも早期に起こることが知られている。また、肥満は糖尿病性心筋障害の増悪因子であると報告されているが、脂肪量との関連は明らかではない。【方法】冠動脈疾患がなく、左室駆出率が保持された73人糖尿病患者を対象とした(女性37人)。左室長軸方向の収縮能はglobal longitudinal strain (GLS)で評価した(異常値:<18%)。体脂肪量は体組成分析装置で測定し、体表面積で補正した(Body Fat Index:BFI)。【結果】単変量解析ではbody mass indexとBFIがGLS<18%と関連していたが、多変量解析ではBFIのみが関連していた。また、BFIとGLSは女性では有意な逆相関を認めたが(r=-0.49, p=0.002)、男性では認められなかった(r=-0.30, Domestic conference2型糖尿病患者の脂肪量と潜在的心機能障害の関連性および予測因子Oral presentation
- The 22th Annual Scientific of the Japanese Heart Failure Society, Oct. 2017, Japanese, The Japanese Heart Failure Society, 秋田, The risk stratification of patients with heart failure (HF) can be performed using echocardiographic parameters such as left ventricular (LV) ejection fraction (LVEF). Since LVEF reflects merely the change in LV volume but does not take into consideration ultrastructural changes that may occur at the myocardial level and that may impair LV systolic performance. Thus, LVEF may n, Domestic conferenceRole of Echocardiographic Strain Imaging for Patients with Heart FailurePublic symposium
- The 65th Annual Scientific of the Japanese College of Cardiology, Sep. 2017, Japanese, Japanese College of Cardiology, 大阪, 【目的】肺高血圧症(PH)患者において、下肢陽圧負荷を用いたpreload stress心エコー図検査を行い、その有用性を検討すること。【方法】対象はPH患者43例(肺動脈性肺高血圧症:24例、慢性肺血栓塞栓性肺高血圧症:19例)とPH群と年齢ならびに性別をマッチさせたと正常コントロール17例とした。全例に安静時ならびに下肢陽圧負荷心エコー図検査を行った(DR. Medomer DM-5000EX, Medo Industries CO., Ltd., Tokyo Japan)。右室収縮能は2次元スペックルトラッキング法を用いて、右室自由壁3領域のpeak longitudinal strainの平均値として評価し(RV free-wall strain)、右室収縮予備能は、下肢陽圧負荷によるRV free-wall strainの相対的変化率とした, Domestic conference肺高血圧症患者における下肢陽圧負荷心エコー図検査の有用性Poster presentation
- The 65th Annual Scientific of the Japanese College of Cardiology, Sep. 2017, Japanese, Japanese College of Cardiology, 大阪, 【背景】左室拡張能障害は糖尿病性心筋障害の主体であるが、左室長軸方向への収縮能の低下がより早期に出現し、予後予測因子であると近年報告されている。本研究は、我々のデータベースを用いて、下記の3点について検討した。(1)左室長軸方向の収縮能と糖尿病合併症との関連、(2)肥満が糖尿病に与える影響、(3)糖尿病患者と正常人における左室拡張能障害の進展の比較【方法】虚血性心疾患が除外され、左室駆出率が保持された(≥50%)糖尿病患者206例と、年齢、性別、左室駆出率をマッチさせた健常者91名を対象とした。左室長軸方向の収縮能の指標として2次元スペックルトラッキング法を用いてglobal longitudinal strain (GLS)を計測した(低下群:GLS<18%)。【結果】GLSと糖尿病合併症との関連多変量ロジスティック解析では、肥満、2型糖尿病、腎症, Domestic conference糖尿病性心筋障害を包括的に読み取るPublic symposium
- The 65th Annual Scientific of the Japanese College of Cardiology, Sep. 2017, Japanese, Japanese College of Cardiology, 大阪, 【背景】アントラサイクリン系薬剤による左室心筋障害は従来の薬物療法への反応が乏しく、予後不良と考えられている。そのため、どのような症例が投与後に左室収縮能障害が出現するのかどうかを予測できれば、臨床上非常に有用である。【方法】左室駆出率が保持された(左室駆出率≥50%)、アントラサイクリン系の化学療法を受けた77例の悪性リンパ腫の患者を対象とした(年齢:63.8±13.8歳、男性:44例、左室駆出率:63±6%)。化学療法後の心エコー図検査で左室駆出率が50%未満に低下した症例または左室駆出率が化学療法前, Domestic conference左室長軸方向の心筋収縮能と抗癌剤性心筋症Public symposium
- The 44th JSUM Kansai Regional Congress of the Japan Society of Ultrasonics in Medicine, Sep. 2017, Japanese, The Japan Society of Ultrasonic in Medicine, 大阪, 症例は75歳女性。44年前に心房中隔欠損孔に対し外科的にパッチ閉鎖術が施行されている。労作時息切れならびに心房中隔欠損症の再発のために当科に紹介となった。経食道心エコー図検査にてValsalva洞付近の心房中隔に外科的修復に使用されたパッチと思われる高輝度エコーと、その下後側に5.9mm×9.1mmの欠損とそれに付随した左右シャント血流を認めた。本症例に対して経皮的心房中隔欠損閉鎖術を施行したが、外科的修復術後の残存欠損孔に対し、また44年前に使用されたパッチの近傍にも関わらず経皮的にデバイス閉鎖した症例は極めて稀であるため報告する。, Domestic conference外科的心房中隔欠損修復後44年後に経皮的心房中隔欠損閉鎖術を施行した高齢女性の一例Oral presentation
- The 44th JSUM Kansai Regional Congress of the Japan Society of Ultrasonics in Medicine, Sep. 2017, Japanese, The Japan Society of Ultrasonic in Medicine, 大阪, 右室機能は様々な心疾患において予後規定因子であると報告されている。肺高血圧症のような右心系の疾患のみならず、拡張型心筋症のような左心系の疾患においても、進行した右室収縮機能不全は死亡や心不全だけでなく突然死の独立した予測因子にもなり得ると報告されている。このように、右室機能評価は重要ではあるが、右室は左室と異なり形態が複雑であるため、回転楕円体と仮定することはできず、単一断面のトレースから右室容積や右室駆出率を算出することは困難である。この右室の形態の複雑さが、心エコー図法による右室機能の定量的評価を困難にしている。 近年2次元スペックルトラッキング ストレイン法を用いた右室機能評価の有用性が数多く報告されている。本手法は米国心エコー図学会(ASE)のガイドラインにも記載されており、右室自由壁3領域の長軸方向のピークストレインの平均値として算出する。, Domestic conferenceストレインを用いた右室機能評価[Invited]Invited oral presentation
- ESC Congress 2017, Aug. 2017, English, European Society of Cardiology, Barcelona, Spain, We presented the clinical utility of leg positive pressure echocardiography for the assessment of patients prognosis., International conferenceThe assessment of contractile reserve and diastolic reserve during non-invasive preload stress echocardiography contributes to the risk stratification for patients with heart failureOral presentation
- 第23回日本心臓リハビリテーション学会学術集会, Jul. 2017, Japanese, Domestic conference肺高血圧症患者における唾液アミラーゼ亢進は運動耐容能低下を反映するOral presentation
- The 2nd Annual Scientific Session of the Japanese Pulmonary Circulation and Pulmonary Hypertension Society, Jun. 2017, Japanese, Japanese Pulmonary Circulation and Pulmonary Hypertension Society, 札幌, 肺高血圧症患者ではその原因となる病態、重症度を同定することが重要であり、これらの評価には心エコー図法が有用である。特に、肺高血圧症患者においては、右室収縮機能の低下は予後不良規定因子であるとも報告されている。そのため、肺高血圧症患者では、右室収縮能評価は重要ではあるが、右室は左室と異なり形態が複雑であるため、回転楕円体と仮定することはできず、単一断面のトレースから右室容積や右室駆出率を算出することは困難である。この右室の形態の複雑さが、心エコー図法での右室機能の定量的評価を困難にしているのが現状である。右室収縮能評価は一般的に大まかな視覚的評価がなされてきたのが現状ではあるが、その基準はきわめて曖昧である。さらに、現在まであまり注目されていなかった右房機能に関しても、肺高血圧症患者において付加的な役割を担っていることも報告されている。 本セッションで, Domestic conference心エコー図による右心機能評価[Invited]Invited oral presentation
- 第123回日本循環器学会近畿地方会, Jun. 2017, Japanese, 日本循環器学会, 大阪, Domestic conference逆Rivero-Carvallo徴候をMRIにて証明したStraight Back Syndromeの一例Oral presentation
- 第123回日本循環器学会近畿地方会, Jun. 2017, Japanese, 日本循環器学会, 大阪, Domestic conference悪性リンパ腫の患者における抗癌剤投与後の左室収縮能低下を予測する因子の検討Oral presentation
- The 28th Annual Scientific Session of the American Society of Echocardiography, Jun. 2017, English, American Society of Echocardiography, Baltimore, USA, Longitudinal strain is an excellent parameter for a measurement of subtle changes in LV systolic function, and a predictor of mortality and cardiac events in non-ischemic cardiomyopathy. LV dispersion by longitudinal strain and circumferential strain may, International conferenceStrain in the Evaluation of Non-ischemic Cardiomyopathy[Invited]Invited oral presentation
- The 28th Annual Scientific Session of the American Society of Echocardiography, Jun. 2017, English, American Society of Echocardiography, Baltimore, USA, International conferencePredictor of left ventricular systolic dysfunction in Patients malignant lymphoma after receiving anthracyclinePoster presentation
- The 28th Annual Scientific Session of the American Society of Echocardiography, Jun. 2017, English, American Society of Echocardiography, Baltimore, USA, Background: Atrial septal defect (ASD) is one of the most common forms of congenital heart disease in adults. In addition, the left-to-right shunt causes inadequate left ventricular (LV) diastolic filling, and reduced LV end-diastolic volume by right vent, International conferenceLeft Ventricular Dispersion as a Parameter for Increase Left Ventricular Stroke Volume in Patients with Atrial Septal Defect following Transcatheter ClosurePoster presentation
- The 28th Annual Scientific Session of the American Society of Echocardiography, Jun. 2017, English, American Society of Echocardiography, Baltimore, USA, International conferenceImpact of Obesity on Left Ventricular Longitudinal Function in Diabetes MellitusPoster presentation
- 第2回日本肺高血圧・肺循環学会学術集会, Jun. 2017, Japanese, 日本肺高血圧・肺循環学会, 札幌, Domestic conferenceCTEPHに対するハイブリッド治療の有効性・安全性についてOral presentation
- The 28th Annual Scientific Session of the American Society of Echocardiography, Jun. 2017, English, American Society of Echocardiography, Baltimore, USA, Background: Atrial septal defect (ASD) causes chronic volume overload on right-sided heart, resulting in right-sided heart failure. Transcatheter closure of ASD currently is widely considered to be the first-choice therapeutic option, but bi-ventricular i, International conferenceBi-ventricular Interaction in Patients with Atrial Septal Defect Following Transcatheter ClosurePoster presentation
- The 90th Annual Scientific Meeting of the Japan Ultrasonics in Medicine, May 2017, Japanese, The Japan Society of Ultrasonics in Medicine, 宇都宮, 大動脈弁閉鎖不全症(AR)に対して大動脈弁形成術が可能か否かの判断には心エコー図法、特に3次元法を含めた経食道心エコー図法(TEE)が極めて有用である。それと同様に術後の評価に対してもTEEは極めて重要である。我々の施設では大動脈弁形成術を施行した患者は全例術後安定期にTEEを施行し、弁の状態を確認し、術後の再発の予測を行っている。本セッションでは、以下に挙げた大動脈弁形成術後に評価すべき重要な項目を、実際の症例を提示しながら講演する。1. 術後のCoaptation Length ならびにEffective Heightの評価(図)大動脈弁形成術直後の評価においては、弁の接合が浅く、弁の接合の位置が低い(左室側にある)症例は遠隔期にARの再発が高いとされている。術直後に評価すべき項目としてはCoaptation LengthとEffective H, Domestic conferenceUtility of echocardiography for the assessment of aortic valve in patients who underwent aortic valve repair[Invited]Invited oral presentation
- The 90th Annual Scientific Meeting of the Japan Ultrasonics in Medicine, May 2017, Japanese, The Japan Society of Ultrasonics in Medicine, 宇都宮, 【背景】TAFRO症候群は、Castleman病の類縁疾患明とし提案され、原因なく急性あるいは亜急性に、全身浮腫(胸腹水)、発熱、骨繊維症、肝脾腫(Thrombocytopenia、Anasasrca、Fevere、Reticuin fibrosis、Organomegaly)の5徴を特徴とする疾患である。2010年には本邦からCastleman病とは異なる独立した疾患単位であることが明らかになった。今回我々はTAFRO症候群に重症心不全を呈し、集学的治療が奏功した症例を経験したので報告する。【症例】17歳男性。インフルエンザ罹患後から持続する発熱、頸部および腋窩リンパ節腫大、胸背部痛ならびに腰痛のために近医を救急受診された。精査では炎症反応の上昇、造影CTでは少量の腹水、肝脾腫を認めた。感染のフォーカスは特定できなかったが、細菌感染が疑われ、抗生剤, Domestic conferenceA case of TAFRO syndrome with severely depressed left ventricular functionOral presentation
- The 90th Annual Scientific Meeting of the Japan Ultrasonics in Medicine, May 2017, Japanese, The Japan Society of Ultrasonics in Medicine, 宇都宮, Domestic conference悪性リンパ腫の患者における抗癌剤投与後の左室収縮能低下を予測する因子の検討Keynote oral presentation
- The 28th Annual Scientific Meeting of the Japanese Society of Echocardiography, Apr. 2017, Japanese, Japanease Society of Echocardiography, 名古屋, 肺高血圧患者における治療後の右室reverse remodelingを予測にはrerative wall thicknessが有用であった, Domestic conference肺高血圧患者における治療後の右室reverse remodelingを予測する因子の検討Oral presentation
- The 28th Annual Scientific Meeting of the Japanese Society of Echocardiography, Apr. 2017, Japanese, Japanease Society of Echocardiography, 名古屋, Domestic conference糖尿病患者における肥満が左室長軸方向の収縮能ならびに左室拡張能に与える影響についてOral presentation
- The 28th Annual Scientific Meeting of the Japanese Society of Echocardiography, Apr. 2017, Japanese, Japanease Society of Echocardiography, 名古屋, 大動脈弁形成術という術式をご存じでしょうか?大動脈弁閉鎖不全症(AR)に対して施行される術式であるが、僧帽弁形成術と同様に、人工弁を留置せずに、自己弁を修復してARを制御する術式である。ARに対する大動脈弁形成術は現時点で標準術式ではなく、大動脈弁置換術があくまで標準術式であるものの、本邦でも、自己弁温存基部置換術を含む大動脈弁形成術を積極的に選択している施設がみられ、ガイドラインよりも早期に手術が施行される場合が多い。弁置換術と異なり、長期成績はまだ不明ではあるが、特に若年者に対しては機械弁の植え込みを回避できるため、有用な術式になり得る。ARに対して大動脈弁形成術が可能か否かの判断には心エコー図法、特に経食道心エコー図法(TEE)が極めて有用である。TEEでは弁の性状の評価や大動脈基部の拡大の有無などを詳細に観察する必要がある。また、3次元TEE, Domestic conference心エコー図と大動脈弁形成術[Invited]Invited oral presentation
- The 81th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2017, Japanese, Japanese Circulation Society, 金沢, Obesity has a greater effect on LV longitudinal function in patients with DM over non-DM healthy subjects. The strict control of obesity in DM patients may be associated with the prevention of HFpEF., Domestic conferenceImpact of Obesity on Left Ventricular Longitudinal Function in Diabetes MellitusPoster presentation
- The 81th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2017, Japanese, The Japanese Circulation Society, 金沢, また、左室拡張能障害と密接に関連する左室の心筋性状として、左室長軸方向の心筋収縮能が重要である。これは2次元スペックルトラッキング法を用いて、標準的な左室心尖部3断面の18領域の長軸方向の最大ストレイン値を平均することによって算出できる(Global Longitudinal Strain:GLS)。GLSは左室駆出率が保持された心不全(HFpEF)では有意に低下していることが報告されており、HFpEFではGLSが低下しているほど予後が悪いとも報告されている。, Domestic conferenceVentriculo-arterial Coupling for Detecting Heart Failure Symptoms in Patients with Severe Aortic Regurgitation and Preserved Left Ventricular Ejection FractionOral presentation
- The 81th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2017, Japanese, The Japanese Circulation Society, 金沢, 本セッションでは心エコー図法による左室拡張能評価のtips and tricks、ならびにGLSの有用性を講演する。, Domestic conferenceUtility of Ventriculo-arterial Coupling to Predict Post-operative Left Ventricular Dysfunction in Patients with Severe Aortic Regurgitation and Preserved Left Ventricular Ejection FractionPoster presentation
- The 81th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2017, Japanese, The Japanese Circulation Society, 金沢, Aims: To evaluate the ability to utilize the Frank-Starling mechanism without significant increase in left ventricular (LV) filling pressure in response to leg-positive pressure (LPP) maneuver could provide prognostic capability for patients with aortic s, Domestic conferenceSignificant prognostic values of acute preload stress echocardiography by using leg-positive pressure maneuver in patients with severe aortic stenosisPoster presentation
- 第84回日本循環器学会学術大会, Mar. 2017, English, 日本循環器学会, 金沢, Domestic conferenceSerum Phosphate Level Predicts Total Aortic Calcification Burden in Patients with Severe Aortic StenosisKeynote oral presentation
- 第81回 日本循環器学会学術集会, Mar. 2017, English, 日本循環器学会, 金沢, Domestic conferenceSafety of Complete Revascularization of Balloon Pulmonary Angioplasty on Chronic Thromboembolic Pulmonary Hypertension beyond Normalized Mean Pulmonary Arterial PressurePoster presentation
- 第81回 日本循環器学会学術集会, Mar. 2017, English, 日本循環器学会, 金沢, Domestic conferenceImprovement of hemodynamics and exercise tolerance should be necessary to achieve better quality of life on chronic thromboembolic pulmonary hypertension.Poster presentation
- 第81回日本循環器学会学術大会, Mar. 2017, English, 日本循環器学会, 金沢, Domestic conferenceComparison of Left Ventricular Outflow Tract Area Estimated by Transthoracic Echocardiography and Measured by Computed TomographyPoster presentation
- The 81th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2017, Japanese, The Japanese Circulation Society, 金沢, Aims: Our aim was to test the hypothesis that cancer-related left ventricular (LV) damage worsened as cancer progresses. We also evaluated if LV dysfunction by cardiotoxicity of anthracycline was associated with stages of cancer and concomitant diseases.M, Domestic conferenceAssociation of left ventricular function with stages of cancer and concomitant diseases in patients with lymphoma and preserved ejection fractionPoster presentation
- 第85回日本循環器学会学術大会, Mar. 2017, English, 日本循環器学会, 金沢, Domestic conferenceAortic Valve Calcification Density Predicts the Hemodynamic Severity of Aortic Stenosis Independently of Aortic Valve AreaPoster presentation
- The 84st Annual Scientific Meetign of the Japanese Circulation Society, Mar. 2017, English, Japanese Circulation Society, 金沢, We conducted a comprehensive quantification of serum metabolites using gas chromatography-mass spectrometry in patients with atrial septal defect to find clues for understanding myocardial metabolic regulation, and demonstrated that circulating 2-aminobut, Domestic conference2-aminobutyric acid as a newly identified modulator of glutathione homeostasis in failing myocardiumOral presentation
- The 9th annual meeting of Japanese society for adult congenital heart disease, Jan. 2017, Japanese, Japanese Society of Adult Congenital Heart Disease, 津, We presented two cases with rapidly progressive obstructive hypertropic cardiomyopathy who succesfully treated with surgical myectomy., Domestic conferenceTwo cases who showed rapid progression of hypertrophic cardiomyopathy in adrescencePoster presentation
- The 27th Japanese Society of Cardiovascular Imaging & Dynamics, Jan. 2017, Japanese, Japanese Society of Cardiovascular Imaging & Dynamics, 津, 左室が大動脈に駆出する血液量に相当する流入血液量を、拡張期に左房から受け入れる機能が左室拡張機能である。左室拡張機能は大きく分けると、拡張早期の流入を規定する能動的な左室弛緩能と拡張中期から後期の血液の流入を規定する左室スティフネスに分けられる。左室弛緩能はエネルギーを要する能動的な左室拡張能であり、左室スティフネスは受動的な左室の硬さを表している。左室拡張機能の指標としては、左室弛緩の指標である左室弛緩時定数(Tau)、左室スティフネスの指標であるスティフネス定数がゴールドスタンダードとされている。しかし、その計測には左室圧記録が必須となり、日常診療でこれらの指標を用いた拡張機能評価が行われることはほとんどない。そのため、日常臨床では通常は心エコー図検査で左室拡張能評価が代用されている。心エコー図検査では左室流入血流速波形、僧帽弁輪運動速波形、肺静, Domestic conference心エコー図による拡張能評価と心筋性状評価Public symposium
- ISHR 2016, Dec. 2016, Japanese, International Society for Heart Research, 東京, Recent studies have shown that the ketone body -hydroxybutyrate (βOHB) acts not only as a carrier of energy but also as a signaling molecule that has a role in diverse cellular functions. Circulating βOHB levels have been previously reported to be increa, Domestic conferenceCompensatory Accumulation of Myocardial β-Hydroxybutyrate Accompanied by SCOT Downregulation in Response to Oxidative StressOral presentation
- The 122th Annual Scientific Meeting of the Kinki Regional Office of the Japanese Circulation Society, Nov. 2016, Japanese, Kinki Regional Office of the Japanese Circulation Society, 大阪, 【目的】下肢陽圧負荷法を用いた急性前負荷増大負荷心エコー図検査により、大動脈弁狭窄症(AS)患者のリスク層別化を行うこと。【方法】対象は高度AS患者54例。心臓死および心不全入院を複合エンドポイントとした。【結果】経過中9例が心事故を認めた。非心事故群では前負荷増大負荷に対しE/e’の上昇なしに一回拍出量の有意な増大を認めたが(SVi 43±9 to 49±10ml/m2, p<0.001)、心事故群ではSViの増大反応を認めず、著明なE/e’の上昇を認めた(25±7 to 32±8, p<0.01)。ま, Domestic conference高度大動脈弁狭窄症患者における前負荷予備能の検討Oral presentation
- American Heart Association Scientific Sessions 2016, Nov. 2016, English, American Heart Association, New Orleans, USA, Background: Identification of heart failure (HF) symptoms in patients with severe aortic regurgitation (AR) and preserved left ventricular (LV) ejection fraction (EF) isclinically important, but assessment of HF symptoms is challenging. In addition, HF sy, International conferenceVentriculo-arterial Coupling to Detect Heart Failure Symptoms in Patients with Severe Aortic Regurgitation and Preserved Left Ventricular Ejection FractionPoster presentation
- American Heart Association Scientific Sessions 2016, Nov. 2016, English, American Heart Association, New Orleans, USA, Background: Patients with chronic aortic regurgitation (AR) suffer from volume and pressure overload. Post-operative left ventricular (LV) systolic function is an important determinant of post-operative prognosis, but its detection is rather difficult. Al, International conferenceUtility of End-systolic Ventricular Elastance for Predicting Post-operative Left Ventricular Dysfunction in Patients with Severe Aortic Regurgitation and Preserved Left Ventricular Ejection FractionPoster presentation
- American Heart Association Scientific Sessions 2016, Nov. 2016, English, American Heart Association, New Orleans, USA, Introduction: Recently, leg-positive pressure (LPP) maneuver, using customized air-bags inflated both lower limbs to maintain a constant loading pressure (90 mmHg for 5 minutes), is reported to be able to apply acute preload stress non-invasively without, International conferenceSignificant prognostic values of acute preload stress echocardiography by using leg-positive pressure maneuver in patients with severe aortic stenosisPoster presentation
- American Heart Association Scientific Sessions 2016, Nov. 2016, English, American Heart Association, New Orleans, USA, Right ventricular relative wall thickness(RV-RWT) could predict mid-term RV reverse remodeling after treatment in PH patients, and was associated with long-term outcomes. Our findings may have clinical implications for better management of PH patients., International conferencePredictor of right ventricular reverse remodeling after treatment in patients with pulmonary hypertensionPoster presentation
- American Heart Association Scientific Sessions 2016, Nov. 2016, English, American Heart Association, New Orleans, USA, Background: Left ventricular (LV) diastolic dysfunction was identified as the earliest functional alteration in the course of diabetic cardiomyopathy, and also established it as an important prognostic marker in patients with diabetes mellitus (DM). Furth, International conferenceImpact of Left Ventricular Longitudinal Functional Mechanics on the Progression of Diastolic Function in Diabetes MellitusPoster presentation
- American Heart Association Scientific Sessions 2016, Nov. 2016, English, American Heart Association, New Orleans, USA, Background: Diabetic nephropathy is independently associated with left ventricle (LV) longitudinal systolic myocardial dysfunction in asymptomatic diabetes mellitus (DM) patients with preserved LV ejection fraction (LVEF). However, the impact of diabetic, International conferenceImpact of Albuminuria on Left Atrial Function Mediated by Left Ventricular Longitudinal Function in Patients with Diabetic MellitusPoster presentation
- American Heart Association Scientific sessions 2016, Nov. 2016, English, American Heart Association, New Orleans, USA, Background and ObjectiveCirculating levels of ketone bodies have been previously reported to be increased in patients with congestive heart failure (HF). Recent studies have shown that the ketone body β-hydroxybutyrate (βOHB) acts not only as a carrier of, International conferenceCompensatory Accumulation of βHydroxybutyrate Accompanied by SCOT Downregulation in Failing HeartsPoster presentation
- The 20th Annual Scientific Meeting of the Japanese Heart Failure Society, Oct. 2016, Japanese, Japanese Heart Failure Society, 札幌, Background: Left ventricular (LV) hypertrophy (LVH) is an independent cardiovascular risk factor for heart failure (HF) patients. The renin-angiotensin system plays a key role in LVH, and since olmesartan increases plasma angiotensin-(1-7) through an incr, Domestic conferenceEffects of a changeover from other angiotensin II receptor blockers to olmesartan on left ventricular hypertrophy in heart failure patientsPoster presentation
- The 20th Annual Scientific Meeting of the Japanese Heart Failure Society, Oct. 2016, Japanese, Japanese Heart Failure Society, 札幌, 重症さ心不全患者における右心機能の有用性に対する講演, Domestic conference右心機能評価の実際Public symposium
- Japanese Pulmonary Hypertension Society(JPHS)・Japanese Pulmonary Circulation Society(JPCS), Oct. 2016, Japanese, Japanese Pulmonary Hypertension Societ,Japanese Pulmonary Circulation Societ, 東京, Domestic conference圧正常化CTEPH患者に対する追加BPA効果の検討Oral presentation
- The 64th Annual Scientific Session of the Japanease College of Cardiology, Sep. 2016, Japanese, Japanese College of Cardiology, 東京, 【背景】肺高血圧患者の右室収縮能は重要な予後予測因子であり、治療後中期の右室のreverse remodelingが長期予後と密接に関連していることを最近我々は報告した。しかし、肺高血圧患者における治療後の右室reverse remodelingを規定する予測因子は明らかではない。【目的】肺高血圧患者において、治療後の右室reverse remodelingを予測する因子を検討し、その因子が長期予後予測に有用か評価すること。【方法】対象は肺高血圧患者54例。治療前の安静時平均肺動脈圧は38±10mmHgであった。心エコー図検査は治療前と治療後10.2±9.6ヵ月後に施行した。右室のreverse remodelingの判定は右室収縮末期面積の15%以上の相対的な減少と定義した。長期予後予測の検討は、エンドポイントを死亡または右心不全による入院とし、5, Domestic conference肺高血圧症患者における治療後の右室reverse remodelingを予測する因子の検討Poster presentation
- The 64th Annual Scientific of the Japanese College of Cardiology, Sep. 2016, Japanese, Japanese College of Cardiology, 東京, 【背景】糖尿病性心筋症初期の特徴は左室拡張障害とされてきたが、近年2次元スペックルトラッキング法が普及し、左室長軸方向への収縮能の低下がより早期に出現し、さらには将来の心血管イベントの予測因子であると報告されるようになった。しかし左室長軸方向の収縮能低下や収縮同期不全が糖尿病患者における拡張能に及ぼす影響については知見がない。【方法】トレッドミル検査ならびに負荷心筋シンチグラフィにて虚血性心疾患が否定され、左室駆出率が保持された(≥50%)糖尿病患者連続177例と年齢、性別をマッチさせた健常者82名を対象とした。2次元スペックルトラッキング法を用いて心尖部3断面18領域モデルのpeak longitudinal strainの平均値をGLS、QRS開始点から各々のpeak strain値までの時間の標準偏差をDispersion indexとし、同一, Domestic conference糖尿病性心筋症の初期病態を心エコー図法の拡張能指標と左室長軸方向収縮期ストレイン指標から解くPublic symposium
- The 64th Annual Scientific of the Japanese College of Cardiology, Sep. 2016, Japanese, Japanese College of Cardiology, 東京, 大動脈弁閉鎖不全症(AR)の診断、重症度評価、原因疾患の同定、手術適応の有無の精査に関しては、心エコー図検査が中心的な役割を果たしている。本セッションではARの術前評価で特に重要な下記の項目について述べる。 心エコー図法によるARの重症度評価通常手術適応と判断されるARは“severe”の症例に限られるため、重症度評価は極めて重要である。弁の逸脱や感染性心内膜炎を合併した症例では逆流ジェットが偏位する場合もあり、逆流シグナルを3次元的に評価することが重要である。ガイドラインに記載されている定量評価法を併用しながら評価することも必要である。左室駆出率が保持された無症候性の重症ARの手術適応ガイドラインに基づいて治療を進めると、左室駆出率が保持された無症状の慢性重症AR患者では、左室収縮末期径が50mmの大きさに拡大するまで内科的治療をせざるを得ず、その, Domestic conference大動脈弁閉鎖不全症の術前診断では何が重要か?Public symposium
- The 64th Annual Scientific of the Japanese College of Cardiology, Sep. 2016, Japanese, Japanese College of Cardiology, 東京, 【背景】 症候性の大動脈弁狭窄症は一般に早期の外科的介入が必要であるとされているが、現在のところ心血管事故に対するリスクの層別化についての明確な指標はない。【目的】前負荷予備能の評価は、症候性の大動脈弁狭窄患者の管理において付加的な予後情報を与える可能性があるとの仮説のもと、下肢陽圧負荷心エコー図法を用いたpreload stress心エコー図検査にて、大動脈弁狭窄症患者のリスクを層別化すること。【方法】症候性の大動脈弁狭窄症患者35例(平均年齢:80±8歳, 大動脈弁弁口面積係数: 0.42±0.12cm2/m2 、左室駆出率: 68±12%)を対象とした。通常の心エコー図検査とともに、下肢陽圧負荷によるpreload stressエコー図検査を施行。一次エンドポイントを心臓死または症状増悪による再入院、複合エンドポイントを大動脈弁置換術と心臓死ま, Domestic conference症候性大動脈弁狭窄症患者における前負荷予備能の検討Oral presentation
- 第214回日本内科学会近畿地方会, Sep. 2016, Japanese, 日本内科学会, 大阪, Domestic conferenceUpfront combination therapyに治療抵抗性を認めた長期覚醒剤乱用歴のある肺動脈性肺高血圧症の一例Oral presentation
- The 64th Annual Scientific of the Japanese College of Cardiology, Sep. 2016, Japanese, Japanese College of Cardiology, 東京, 【背景】糖尿病性腎症を有する患者では左室駆出率が保持されていても左室長軸方向への収縮が低下している。しかしながら、左房機能と腎症の関係性のみならず、その関係性に左室長軸方向への収縮能を介した知見はない。【方法】虚血性心疾患が否定され、左室駆出率が保持された(≥50%)糖尿病患者連続198例と年齢、性別をマッチさせた健常者60名を対象とした。2次元スペックルトラッキング法を用いて、心尖部3断面18領域モデルのpeak longitudinal strainの平均値をGLSとして算出した。また、左房の収縮期最大strainをLAS-s (reservoir function)、拡張後期の左房収縮strainをLAS-a (contractile function)と定義し、心尖部2腔像、4腔像での平均値として算出した。24時間蓄尿での尿中アルブミン排泄率, Domestic conference2次元スペックルトラッキング法でみた左室-左房連関に及ぼす糖尿病性腎症の影響Poster presentation
- The 121th Annual Scientific Meeting of the Kinki Regional Office of the Japanese Circulation Society, Jul. 2016, Japanese, Kinki Regional Office of the Japanese Circulation Society, 京都, 背景:アンジオテンシンII受容体拮抗薬(ARB)は心肥大退縮効果を有しているが、中でもオルメサルタンはアルドステロンブレイクスルーを起こしにくいことが報告されており、より強力な心肥大抑制効果が期待される。方法:他剤ARBをすでに1年以上投与された慢性心不全患者59例を対象とし、オルメサルタンに変更後6ヶ月後の心肥大退縮効果、BNPの変化を検証した。結果:血圧、心拍数に有意な変化を認めなかったが、左室心筋重量係数は有意に減少し(119±38 g/m2 vs. 110±24 g/m2、p=0.007)、BNPは改善傾向であった(52pg/mL vs. 40pg/mL、p=0.2)。結論:オルメサルタンはARBの中で、より左室肥大の退縮に寄与する可能性が示唆された。, Domestic conferenceEffects of a Change-Over from Other Angiotensin II Receptor Blockers to Olmesartan on Left Ventricular Hypertrophy in Heart Failure PatientsOral presentation
- The 22nd Annual Meeting of the Japanese Association of Cardiac Rehabilitation, Jul. 2016, Japanese, 日本心臓リハビリテーション学会, 東京, Domestic conference心肺運動負荷試験結果に基づく運動療法は肺高血圧症患者の気分状態を即時的に改善させるOral presentation
- The 121th Annual Scientific Meeting of the Kinki Regional Office of the Japanese Circulation Society, Jul. 2016, Japanese, Kinki Regional Office of the Japanese Circulation Society, 京都, 背景:アンジオテンシンII受容体拮抗薬(ARB)は心肥大退縮効果を有しているが、中でもオルメサルタンはアルドステロンブレイクスルーを起こしにくいことが報告されており、より強力な心肥大抑制効果が期待される。方法:他剤ARBをすでに1年以上投与された慢性心不全患者59例を対象とし、オルメサルタンに変更後6ヶ月後の心肥大退縮効果、BNPの変化を検証した。結果:血圧、心拍数に有意な変化を認めなかったが、左室心筋重量係数は有意に減少し(119±38 g/m2 vs. 110±24 g/m2、p=0.007)、BNPは改善傾向であった(52pg/mL vs. 40pg/mL、p=0.2)。結論:オルメサルタンはARBの中で、より左室肥大の退縮に寄与する可能性が示唆された。, Domestic conferenceEffects of a Change-Over from Other Angiotensin II Receptor Blockers to Olmesartan on Left Ventricular Hypertrophy in Heart Failure PatientsOral presentation
- The 121th Annual Scientific Meeting of the Kinki Regional Office of the Japanese Circulation Society, Jul. 2016, Japanese, Kinki Regional Office of the Japanese Circulation Society, 京都, 【目的】経皮的心房中隔欠損閉鎖術(ASO)後の両心室の変化と、左室の心拍出量増加に寄与する因子が何であるかを検討すること。【方法】対象はASOが施行された心房中隔欠損症70例。術前および術後3ヶ月に左室心筋機能の評価として、global longitudinal strainとLV dispersion(左室収縮のばらつき)を、右室収縮能指標としてRV free-wall strainを算出した。【結果】ASO後にRV free-wall strainは有意に低下し、LV dispersionは有意に低下した。多変量解析ではRV free-wall strainの変化率とLV dispersionの変化率が、ASO後の左室心拍出量の増加に寄与する独立した規定因子であった。【結語】LV dispersionならびにRV free-wall strain, Domestic conference経皮的心房中隔欠損閉鎖術前後における両心室間の相互作用と心拍出量増加についてOral presentation
- 第213回日本内科学会近畿地方会, Jul. 2016, Japanese, 日本内科学会, 大阪, Domestic conferenceUpfront combination therapyにより肺水腫を来した肺動脈性高血圧症の1例Oral presentation
- The 212th Annual Scientific Meeting of the Kinki Regional Office of the Japanese Society of Internal Medicin, Jun. 2016, Japanese, The Japanese Society of Internal Medicine, 大阪, 【症例】22歳男性【主訴】胸部不快感、呼吸困難感【現病歴】生後9か月時に心雑音を指摘され、肥大型心筋症と診断。その後の遺伝子診断でRAF1遺伝子変異が確認され、Noonan症候群と確定診断された。当初薬物療法と運動制限により自覚症状なく経過していたが、2014年末頃より胸部不快感、呼吸困難感を自覚するようになった。心エコー図検査では心室中隔厚42mm、左室後壁厚30mmと著明な求心性左室肥大を認め、それに伴い心尖部、心室中部、および左室流出路にそれぞれ有意な動的閉塞を認めた。また、右室自由壁の肥大に伴う著明な右室内閉塞も併存していた。両心室の閉塞性肥大型心筋症による前方駆出の制限が症状の原因であると判断。これに対し、心尖部から流出路にかけての左室心筋切除、および右室流出路の心筋切除術を施行した。術後心内腔の拡大を認め、両心室における動的閉塞は解除され, Domestic conference外科的心筋切除術が奏功した、Noonan症候群に合併した両心室閉塞性肥大型心筋症の1例Oral presentation
- The 89th Annual Scientific Meeting of the Japan Ultrasonics in Medicine, May 2016, English, The Japan Society of Ultrasonics in Medicine, 京都, Right ventricular (RV) systolic function is a major determinant of prognosis for patients with pulmonary hypertension (PH), but it has remained unclear what is the best available noninvasive method for measuring RV systolic function. One of these methods, Domestic conferenceUtility of Echocardiography in Right-sided Heart for Better Management of Patients with Pulmonary HypertensionPublic symposium
- The 89th Annual Scientific Meeting of the Japan Ultrasonics in Medicine, May 2016, English, The Japan Society of Ultrasonics in Medicine, 京都, Duchenne muscular dystrophy (DMD) is an X-linked recessive disease affecting approximately 1 in 3,500 live-born male children worldwide. DMD is caused by mutations in the dystrophin gene that result in marked reduction or absence of the sarcolemnal protei, Domestic conferenceEchocardiographic Assessment of Subclinical Left Ventricular Dysfunction in Patients with Duchenne Muscular DystrophyPublic symposium
- The 89th annual scientific meeting of the Japanese society of ultrasonography, May 2016, Japanese, The Japan society of ultrasonics in medicine, 京都, We introduced the usefulness of the assessment of Non-invasive single-beat ventriculo-arterial coupling, Domestic conferenceClinical Application of Quantitative Assessment of Ventriculo-arterial Coupling by Using Non-invasive Single-beat MethodPublic symposium
- The 89th Annual Scientific Meeting of the Japan Society of Ultrasonics in Medicine, May 2016, Japanese, Japan Society of Ultrasonics in Medicine, 京都, 【背景】近年高齢者の心房中隔欠損(ASD)患者に対する、経皮的心房中隔欠損閉鎖術(ASO)は増加傾向にある。ASO後の右心負荷の軽減や左室の心拍出量の増大が、ASD患者の症状ならびに予後の改善に関連していると考えられている。しかしながら、ASO前後における両心室間の相互関係や、ASO後の左室心拍出量の増加に寄与する因子については十分に検討されていない。【目的】ASO後の両心室の変化と、左室の心拍出量増加に寄与する因子が何であるかを検討すること。【方法】ASOを施行されたASD患者70名を対象とした(平均年齢:57±16歳、女性:42例、左室駆出率:72±8%)。全例術前および術後3ヶ月に心臓超音波検査を施行した。左室心筋機能の評価として、2次元スペックルトラッキング法を用いて、左室18領域のpeak strain値の平均であるGlobal longi, Domestic conference経皮的心房中隔欠損閉鎖術前後における両心室間の相互作用についてOral presentation
- The 89th Annual Scientific Meeting of the Japan Ultrasonics in Medicine, May 2016, Japanese, The Japan Society of Ultrasonics in Medicine, 京都, 背景:中等度以上の二次性三尖弁閉鎖不全症(TR)は、右心不全の増悪因子となり、右心系のみならず左心系の疾患の予後増悪因子になることが知られている。中等度以上の二次性TRに関与する因子として弁輪拡大やtetheringによるメカニズムが報告されているが、二次性TRの原因は多岐にわたり、それらの進行の様式の違いは明らかではない。目的:3次元心エコー図法を用いて三尖弁の形態評価を行い、中等度以上の二次性TRに関与する因子と、それらの因子に影響を与えている右心系の要因を検討すること。方法:二次性TRを有する65名を対象とした(心房中隔欠損症:25名、肺高血圧症:21名、拡張型心筋症:19名)。TRは逆流ジェットエリアおよびその右房面積との比にvena contracta、肝静脈逆流波を加味して重症度を評価行った。三尖弁の形態指標として3次元心エコー図を用いて, Domestic conferenceTricuspid Valve Deformation Associated Factors In Functional Tricuspid RegurgitationPublic symposium
- The 27th Annual Scientific Meeting of Japanese Society of Echocardiography, Apr. 2016, Japanese, Japanease Society of Echocardiography, 大阪, 【背景】肺高血圧患者では様々な因子が予後と関連しているが、中でも右室収縮能は重要であり、右室収縮能障害の進行は予後と関連している。我々は治療後中期の右室のreverse remodelingが長期予後と密接に関連していることを最近報告した。しかしながら、肺高血圧患者における治療後の右室reverse remodelingを規定する因子は明らかではない。【方法】肺高血圧患者54例を対象とした(安静時平均肺動脈圧:38±10mmHg)。心エコー図検査は治療前と治療後10.2±9.6ヵ月後に施行した。治療後の右室reverse remodelingは右室収縮末期面積の15%以上の相対的な減少と定義した。長期予後予測の検討は、エンドポイントを死亡または右心不全による入院とし、5年間追跡した。【結果】54人中10人(19%)にイベントが発生した(死亡:7人、右, Domestic conference肺高血圧症患者では、何が治療後の右室reverse remodelingに関与しているのか?Oral presentation
- The 27th Annual Scientific Meeting of Japanese Society of Echocardiography, Apr. 2016, Japanese, Japanease Society of Echocardiography, 大阪, 【目的】左室拡張能障害が糖尿病性心筋症の初期指標と考えられてきたが、我々は心周期全体での心機能評価の重要性を考え、左室長軸方向の収縮能低下や同期不全が拡張能に及ぼす影響について検証した。【方法】左室駆出率が保持され、冠疾患が否定された糖尿病患者177例と年齢、性別をマッチさせた健常者82例を対象とした。2次元スペックルトラッキング法を用い、心尖部18領域からglobal longitudinal strain (GLS)、time-to-peak strainの標準偏差であるDispersion indexを計測した。先行文献に基づきGLS<18%を左室収縮能低下群と規定した。【結果】ANCOVA(共変量=年齢)では健常者、GLSの保持された糖尿病患者、GLSの低下した糖尿病患者の順で拡張能指標は段階的な悪化を示した。糖尿病患者での多変量解析では、E, Domestic conference左室長軸方向の収縮能低下と同期不全の増大が糖尿病患者の拡張能低下に及ぼす影響Oral presentation
- The 27th Annual Scientific Meeting of the Japanese Society of Echocardiography, Apr. 2016, Japanese, Japanease Society of Echocardiography, 大阪, 症例は既往歴のない56歳女性。2015年8月2日自宅で椅子に座っている時に意識消失を来したが経過観察とした。翌日には歩行時の浮遊感を自覚しその後に再度意識消失を来した。その後も意識消失を繰り返し認めたため8月7日に近医を受診され心電図上高度房室ブロックを認めたためペースメーカー植え込み術目的で8月10日に高次病院へ入院となった。入院後の経胸壁心エコー図検査で大動脈周囲の腫瘤を認め、心臓MRIで同部位にT2W1で高信号、遅延造影でのenhanceを認めた。その後に完全房室ブロック、うっ血肝の増悪を認めたため右内頸静脈より一時ペースメーカーを留置された。悪性リンパ腫や肉腫など悪性腫瘍に伴う可能性を考慮され、精査加療目的に8月11日に当院へ転院となった。当院にて施行した経胸壁心エコー図検査では大動脈周囲に最大径27.1×12.7mmの比較的平滑で可動性のな, Domestic conference完全房室ブロックで発症し、悪性が疑われた大動脈周囲腫瘍の1例Oral presentation
- The 27th Annual Scientific Meeting of the Japanese Society of Echocardiography, Apr. 2016, Japanese, Japanease Society of Echocardiography, 大阪, 右室収縮能は様々な心疾患において独立した予後規定因子でありその評価は重要である。心エコー図ガイドラインにおいてはTAPSEを含めた従来の指標が推奨されており、本セッションではそれらの指標および二次元スペックルトラッキング法、三次元心エコー図法さらに右房機能について概説する。, Domestic conference右心機能評価と心エコー図法[Invited]Nominated symposium
- The 27th Annual Scientific Meeting of Japanese Society of Echocardiography, Apr. 2016, English, Japanease Society of Echocardiography, 大阪, A 58-year-old female was admitted to our hospital because of exertional dyspnea. Echocardiography revealed a 20× 35 mm mass arising from the papillary muscles and involved the chordae tendineae. The mass was seen across the mitral valve in diastole, causi, Domestic conferenceHeart Failure with Functional Mitral Valve Stenosis Due to Left Ventricular Myxoma Originating from Papillary Muscle[Invited]Nominated symposium
- The 27th Annual Scientific Meeting of Japanese Society of Echocardiography, Apr. 2016, Japanese, Japanease Society of Echocardiography, 大阪, 心臓再同期療法(CRT)における心エコー図法の役割は何だろうか?CRTは心不全の治療法の一つであるので、一般的な心機能評価としての心エコー図法の重要性は言うまでもない。過去にはDyssynchronyの定量評価としての心エコー図法の有用性が報告されていたが、PROSPECT trial(Circulation 2008;117:2608-16)やJ-CRT(Circ J. 2011;75:1156-63)などの大規模臨床試験で、それは否定されている。しかしながらスペックルトラッキング法を用いると、Dyssynchronyがより正確に定量評価でき、試適左室リード位置の同定にも有用であるなど、CRTに対する有用性も数多く報告されている。 CRTに関する臨床研究の発展により、適応基準を満たす患者群の中でも、洞調律、左脚ブロック、QRS幅≥150ms、非虚血, Domestic conferenceBorderline QRS/非左脚ブロック症例におけるCRT[Invited]Nominated symposium
- The 27th Annual Scientific Meeting of Japanese Society of Echocardiography, Apr. 2016, Japanese, Japanease Society of Echocardiography, 大阪, 2次元スペックルトラッキング法を用いて初期の糖尿病性心筋症が同定可能であることが報告されているが、どのような特徴をもった糖尿病患者に心筋症が存在するのか知見が少なかった。更に、標準的な拡張能の指標との関連も不明であった。そこで左室駆出率が保持され、冠疾患が否定された糖尿病患者を登録し心エコー図を施行し、心尖部3断面からglobal longitudinal strain (GLS)を計測した。糖尿病の背景、病状、微小血管合併症(腎症、網膜症、神経症)を糖尿病内科専門医が詳細に評価した。合併症として糖尿病性腎症が最も強い糖尿病性心筋症のリスクファクターであり、尿中アルブミン量とGLSには相関関係を認めた。神経症もまた独立した心筋症のリスクファクターであり、神経症の鋭敏な指標であるF波潜時の延長はGLSと強い関連があった。さらに各種左室拡張能の低下にGL, Domestic conference2次元スペックルトラッキング法を用いた糖尿病性心筋症の同定とその臨床的患者背景についての検討[Invited]Invited oral presentation
- The 80th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2016, Japanese, The Japanese Circulation Society, 仙台, Domestic conference肺動脈性肺高血圧症および慢性血栓塞栓性肺高血圧症患者に対する運動耐容能および血行動態評価として心肺運動負荷試験は有用であるPoster presentation
- The 80th Annual Scientific Meeting of Japanese Circulation Socisty, Mar. 2016, Japanese, Japanese Circulation Society, 仙台, Background: Atrial septal defect (ASD) causes chronic volume overload on right-sided heart, but the potential adverse effects of this long-standing volume overload to left ventricle as well as the response to ASD closure remains unclear. Methods: Fifty-th, Domestic conferenceBi-ventricular Interaction in Patients with Atrial Septal Defect Following Transcatheter ClosureOral presentation
- 第80回日本循環器学会総会, Mar. 2016, English, 日本循環器学会, 仙台, Domestic conferenceExamination of the correlation between Health Related Quality of Life scores and parameters from six-minute walk test in pulmonary hypertensionOral presentation
- The 80th Annual Scientific Meeting of Japanese Circulation Socisty, Mar. 2016, Japanese, Japanese Circulation Society, 仙台, Background: It was reported that olmesartan increases plasma angiotensin-(1-7) through an increase in angiotensin-converting enzyme-related carboxypeptidase expression, resulting in a reducing left ventricular (LV) hypertrophy in animal models. Therefore,, Domestic conferenceEffects of a Change-Over from Other Angiotensin II Receptor Blockers to Olmesartan on Left Ventricular Hypertrophy in Heart Failure PatientsOral presentation
- The 80th Annual Scientific Meeting of Japanese Circulation Socisty, Mar. 2016, Japanese, Japanese Circulation Society, 仙台, Background: Right ventricular (RV) function is an important determinant of outcome for pulmonary hypertension (PH) patients, and elevated right atrial (RA) pressure is reported to be a prognostic factor. The purpose of this study was to evaluate the relat, Domestic conferenceComprehensive Functional Assessment of Right-Sided Heart Using Speckle-Tracking Strain for Patients with Pulmonary HypertensionOral presentation
- 第80回日本循環器学会総会, Mar. 2016, English, 日本循環器学会, 仙台, Domestic conferenceCharacterization of the patients with sustained low oxygen saturation at one year after balloon pulmonary angioplasty.Oral presentation
- 第18回日本成人先天性心疾患学会学術集会, Jan. 2016, Japanese, 日本成人先天性心疾患学会 (JSACHD), 大阪, Domestic conferenceClinical feature of post operative pulmonary hypertension in congenital heart diseasePublic symposium
- The 18th Annual Meeting of Japanese Society for Adult Congenital Heart Disease, Jan. 2016, Japanese, Japanese Society for Adult Congenital Heart Disease, 大阪, Background: Atrial septal defect (ASD) causes chronic volume overload on right-sided heart, but the potential adverse effects of this long-standing volume overload to left ventricle as well as the response to ASD closure remains unclear. Methods: We studi, Domestic conferenceBi-ventricular Interaction in Patients with Atrial Septal Defect Following Transcatheter ClosurePoster presentation
- The 18th Annual Meeting of Japanese Society for Adult Congenital Heart Disease, Jan. 2016, Japanese, Japanese Society for Adult Congenital Heart Disease, 大阪, Background: Prognostic factors after transcatheter closure for adult patients with atrial septal defect (ASD) have not been fully identified. Methods: Forty-nine patients who underwent transcatheter ASD closure were recruited for this study. Echocardiogra, Domestic conferenceUtility of Isovolumic Contraction Peak Velocity for Evaluation of Adult Patient Status after Transcatheter Closure of Atrial Septal DefectOral presentation
- The 5th Japanese Heart Valve Society, Nov. 2015, Japanese, Japanese Heart Valve Society, 東京, 大動脈弁閉鎖不全症(AR)に対して大動脈弁形成術が可能か否かの判断には心エコー図法、特に経食道心エコー図法(TEE)が極めて有用である。また、3次元TEE(3D-TEE)は弁の詳細な評価に有用であり、弁の逸脱部位や逸脱範囲、弁葉のサイズ、大動脈基部の情報など2次元TEEよりも正確な評価が可能である。特に多断面再構成法(MPR法)は、各弁尖に対して任意の断面を描出することが可能であり、病変部位の同定ならびに詳細な病変の評価に有用である。以下に大動脈弁形成術を考慮する症例における、評価すべき重要な項目を挙げる。1. ARの機能的分類の評価 Carpentierらによって提唱された僧帽弁閉鎖不全症の機能的分類と同様に、El KhouryらのグループはARの機能的分類を提唱している。これは特に大動脈弁形成術を念頭に置いた分類であり、各タイプ別に推奨される術式, Domestic conference大動脈弁形成術に必要な画像診断[Invited]Nominated symposium
- The 120th Kinki Regional Office of the Japanese Circulation Society, Nov. 2015, Japanese, Japanese Circulation Society, 大阪, 【背景】徐脈性不整脈の患者においては、恒久的ペースメーカー療法後の左室駆出率(EF)の低下を事前に予測する事は困難である。【目的】右室ペーシングによる心機能低下の違いを検討すること。【方法】植え込み型除細動器が植え込まれた38例を対象とし、安静時、右室ペーシング時のEFの変化ならびに左室内同期不全の程度を比較した。【結果】EF軽度低下群(35-50%、17例)ではEF正常群(50%以上、21例)と比較して、右室ペーシングによるEFの低下が有意に大であり、また左室内同期不全が有意に悪化した。【結論】心臓再同期療法の適応基準を満たさないEFが軽度低下した徐脈性不整脈症例では、通常のペースメーカーの植え込みでなく、心臓再同期療法を選択した方が将来の心筋障害を予防できる可能性が示唆された。, Domestic conference軽度左室機能低下患者における右室ペーシングの影響Oral presentation
- American Heart Association scientific session 2015, Nov. 2015, English, American Heart Association, Orland, USA, GCS would be closely associated with LV myocardial viability in HF patients. RV free-wall longitudinal strain is promising tools for the evaluation of RV myocardial viability in HF patients. Thus, assessment of speckle tracking strain offers an even bette, International conferenceStrain for Myocardial Viability[Invited]Nominated symposium
- American Heart Association scientific session 2015, Nov. 2015, English, American Heart Association, Orland, USA, Background: Although right ventricular (RV) pacing is the only effective treatment for patients with symptomatic atrioventricular block, it creates left ventricular (LV) mechanical dyssynchrony, which can induce LV dysfunction and heart failure. Current c, International conferenceRisk Stratification of Future Left Ventricular Dysfunction in Patients with Indication for Right Ventricular Pacing Owing to BradycardiaPoster presentation
- American Heart Association scientific session 2015, Nov. 2015, English, American Heart Association, Orland, USA, Background: Current guidelines recommend implantation of prophylactic implantable cardioverter-defibrillators (ICD) in patients with left ventricular (LV) ejection fraction (EF) <35%. We explored the prognostic factors of fatal ventricular arrhythmias for, International conferenceLeft ventricular dyssynergy and dispersion as determinant factors of fatal ventricular arrhythmias in patients with mildly reduced ejection fractionPoster presentation
- American Heart Association scientific session 2015, Nov. 2015, English, American Heart Association, Orland, USA, Introduction: Increasing stimulus strength of left ventricular (LV) coronary sinus pacing decreases QRS duration and inter-ventricular conduction time. Hypothesis: Increasing stimulus strength of LV coronary sinus pacing improves LV mechanical dyssynchron, International conferenceIncreasing Stimulus Strength of Coronary Sinus Pacing Improved Left Ventricular Mechanical Dyssynchrony and Contractile Function in Patients with Reduced Ejection FractionPoster presentation
- American Heart Association scientific session 2015, Nov. 2015, English, American Heart Association, Orland, USA, Introduction: Background: Functional tricuspid regurgitation (FTR) is widely recognized as being associated with poor outcomes in patients with various cardiac diseases, and the tricuspid valve (TV) deformation is an important mechanism of FTR. However, t, International conferenceAssociation of Three-Dimensional Tricuspid Valve Deformation with Functional Tricuspid RegurgitationPoster presentation
- The 19th Annual Scientific Meeting of the Japanese Heart Failure Society, Oct. 2015, Japanese, The Japanese Heart Failure Society, 大阪, Domestic conferenceCardio pulmonary Exercise Testing is Valuable for Assessing Exercise Capacity and Hemodynamic Status in Patients with Chronic Thromboembolic Pulmonary HypertensionOral presentation
- 第4回日本肺循環学会、第3回日本肺高血圧学会, Oct. 2015, Japanese, Japanese Pulmonary Circulation Siciety, Japanese Pulmonary Hypertension Society, 東京, CPXはPH患者の機能障害の評価のみならず、治療効果判定、予後予測に有用であり、付加的な診断法として期待されている。, Domestic conference肺高血圧症患者における心肺運動負荷試験の重要性[Invited]Nominated symposium
- The 19th Annual Meeting of the Japanese Heart Failure Society, Oct. 2015, Japanese, The Japanese Heart Failure Society, 大阪, Aim: Right ventricular (RV) as well as left ventricular (LV) function, has been recognized as an important prognostic factor for heart failure patients. Our objective was to investigate the prognostic significance of combined assessment of bi-ventricular, Domestic conferenceAssessment of Bi-ventricular Contractile Reserve for Patients with Left-sided Heart FailurePublic symposium
- 第4回日本肺循環学会(JPCS)第3回日本肺高血圧学会(JPHS)合同学術総会, Oct. 2015, Japanese, 日本肺循環学会(JPCS)/日本肺高血圧学会(JPHS), 東京, Domestic conferenceインドネシアと日本における心房中隔欠損症患者の疫学比較調査Oral presentation
- The 21th Annual Scientific Meeting of the Japanese Association of Cardiac Rehabilitation, Jul. 2015, Japanese, The Japanese Association of Cardiac Rehabilitation, 福岡, 【背景】当施設では新規肺高血圧症(PH)患者に対し、内科的、外科的治療を行う前の診断時から心臓リハビリテーション(心リハ)を行っている。【方法】2010年6月から2014年12月までに、診断時から心肺運動負荷試験を用い運動耐容能評価を行ったPH患者41例(年齢57±16歳、女性28例、治療前平均肺動脈圧:37.8±12.8mmHg、心係数:2.4±0.8 l/min/m2)を対象に治療前後の運動耐容能の変化を検討した(観察期間:293±261日)。【結果】治療後、運動耐容能は有意に改善したが、依然として低値であった(%予測最高酸素摂取量:46.8±11.8% vs. 58.6±14.0% p<0.0001, VE/VCO2 slope 45.1±13.9 vs. 36.6±12.5 p<0.0001)。対象患者のうち、心不全による再入院が5/41例、, Domestic conference肺高血圧症治療における心臓リハビリテーションと運動耐容能評価―診断時から回復期に渡る長期介入の提言―Public symposium
- The 21th Annual Scientific Meeting of the Japanese Association of Cardiac Rehabilitation, Jul. 2015, Japanese, The Japanese Association of Cardiac Rehabilitation, 福岡, Domestic conference左心補助人工心臓(LVAS)から離脱した症例における運動能力と社会心理的指標の推移Poster presentation
- The 79th Annual Scientific Meeting of the Japanese Circulation Society, Apr. 2015, Japanese, The Japanese Circulation Society, 大阪, 【背景】 慢性血栓塞栓性肺高血圧症(CTEPH)に対する治療目標として心肺運動負荷試験(CPX)指標の1つである最高酸素摂取量(Peak VO2)が用いられているが、バルーン肺動脈形成術(BPA)によるCTEPH患者のPeak VO2改善に関与する術前因子および治療前後変化に関する検討を認めない。【方法】2011年5月から2014年10月までに当院循環器内科にてBPAおよび治療前後評価としてCPXが施行されたCTEPH患者連続20例(年齢63±12歳、女性14例)を対象とし、後ろ向き解析を行った。BPA前後のPeak VO2改善(Δ Peak VO2)の中央値であった2.4ml/kg/minをカットオフ値とし、Responder群(RG、11例とNon-responder群(NRG、9例)の2群に分類し、術前因子および治療前後変化に関する比較検討を行, Domestic conferenceバルーン肺動脈形成術による慢性血栓塞栓性肺高血圧症患者の最高酸素摂取量改善に関与する術前因子および治療前後変化の検討Poster presentation
- The 64th Annusl Scientific Session of the American College of Cardiology, Mar. 2015, English, American College of Cardiology, San Diego, USA, RV systolic function was shown to correlate significantly with LV filling in PH patients. Furthermore, not only assessment of RV systolic function, but also of a combined bi-ventricular parameter comprising RV systolic function and LV filling may well have clinical implications for more successful management of PH patients., International conferenceInterdependence of Right Ventricular Systolic Function and Left Ventricular Filling and its Association with Outcome for Patients with Pulmonary HypertensionOral presentation
- The 64th Annusl Scientific Session of the American College of Cardiology, Mar. 2015, English, American College of Cardiology, San Diego, USA, Combined assessment of baseline RV function and mid-term reverse-remodeling in right-sided heart yields more accurate prediction of outcomes for PH patients after treatment with PH-specific drugs., International conferenceCombined Assessment of Right Ventricular Function and Mid-Term Reverse Remodeling in Right-Sided Heart Enhances Prognostic Capability for Pulmonary Hypertension Patient Outcome after Medical TreatmentPoster presentation
- The 26th Annual Metting of the Japanese Society of Echocardiography, Mar. 2015, Japanese, Japanese Society of Echocardiography, 北九州, 【背景】糖尿病患者における無症候性左室心筋障害が近年報告され、特に左室長軸方向の心筋収縮能の低下は心不全発症の独立した危険因子であるとされている。一方で心筋障害をきたす患者背景の特徴、危険因子の層別化は十分検討されていない。【方法】冠動脈疾患のない左室駆出率の保たれた糖尿病患者117例を対象とした(年齢:59±14歳、女性:63例、左室駆出率:66±4%)。Global longitudinal strain(GLS)は2次元スペックルトラッキング法を用いて左室心尖部3断面から算出し、過去の報告に基づき糖尿病患者における左室心筋障害をGLS<18%と定義した。24時間蓄尿での尿中アルブミン量30mg/日以上を腎症、末梢神経症状と神経伝達速度異常が存在する例を神経症、単純性網膜症以上の存在を網膜症、Body Mass Index≥25kg/m2を肥満と, Domestic conferenceImpact of Microvascular Complications on Left Ventricular Longitudinal Function in Patients with Diabetes Mellitus and Preserved Left Ventricular Ejection Fraction[Invited]Invited oral presentation
- The 64th Annusl Scientific Session of the American College of Cardiology, Mar. 2015, English, American College of Cardiology, San Diego, USA, Background: Left ventricular (LV) longitudinal function was related to subclinical LV dysfunction and development of heart failure in patients with diabetes mellitus (DM) and preserved LV ejection fraction (EF). However, the association of LV longitudinal dysfunction with major three diabetes-related microvascular complications including nephropathy, retinopathy and neuropathy, International conferenceImpact of Microvascular Complications on Left Ventricular Longitudinal Function in Patients with Diabetes Mellitus and Preserved Left Ventricular Ejection FractionPoster presentation
- The 26th Annual Metting of the Japanese Society of Echocardiography, Mar. 2015, Japanese, Japanese Society of Echocardiography, 北九州, 右室収縮能は様々な心疾患において予後規定因子であると報告されている。肺高血圧症患者では、右室収縮機能の低下は、独立した予後規定因子であることが多数の研究結果から証明されおり、さらに左心不全患者においても、右室収縮能の低下は心血管イベントの発生に強く関与していると報告されている。ゆえに、右室収縮能を評価することは日常臨床において重要であるが、その複雑な形態のため、一筋縄ではいかないのが現実である。米国心エコー図学会のガイドラインに明記されている右室収縮能の指標に加えて、近年、2次元スペックルトラッキング法により算出された右室自由壁の長軸方向のストレインが右室収縮能を鋭敏に表すと報告されている。しかしながら、心不全患者における右房評価の有用性や左心機能との関連性については、まだ十分に検討されていない。我々は、肺高血圧症患者において右室収縮能のみならず、右, Domestic conferenceBi-ventricular contractile reserve offers an incremental prognostic value for patients with dilated cardiomyopathy[Invited]Invited oral presentation
- The 64th Annusl Scientific Session of the American College of Cardiology, Mar. 2015, English, American College of Cardiology, San Diego, USA, Background: Uneven wall motion abnormalities characterized by the presence of dyskinetic or akinetic segments coexistent with normokinetic segments have been frequently observed in cardiac sarcoidosis. Case: A 65-year-old man was referred to our hospital because his acute heart failure (HF) had not improved in spite of having undergone optimal pharmacological therapy. Echocardi, International conferenceCardiac Sarcoidosis with Acute Heart Failure Presenting as Dilated CardiomyopathyPoster presentation
- 第7回植込みデバイス関連冬季大会, Feb. 2015, Japanese, 日本不整脈学会, 東京, Domestic conferenceGlenn手術既往のある心室品拍患者に対して、心外膜にICDリードを留置した1例Oral presentation
- The 5th Annual Scientific Meeting of Japanese Society of Heart Valve Disease, Dec. 2014, Japanese, Japanese Society of Heart Valve Disease, 東京, 3次元経食道心エコー図法(3D-TEE)では、2次元経食道心エコー図法(2D-TEE)で得られる情報に加えて、3次元のボリューム情報を得られることができるため、病変の空間的な広がりを瞬時に把握することができる。よって弁膜疾患では、3D-TEEを施行することで、僧帽弁疾患では詳細な逸脱部位の同定、大動脈弁疾患では、大動脈弁を含む大動脈弁複合体の形態異常の正確な位置、広がりの程度を適切に評価することができる。また、3D-TEE法で得られた3次元情報を元に作成した複数の2次元画像を用いることで、2D-TEEでは描出不可能であった任意の断面が得られることができる。これは多断面再構成法multi-planar reconstruction(MPR法)という手法であり、僧帽弁、大動脈弁を各弁尖ごとに評価することが可能である。また、これまでの2次元画像では超音波ビ, Domestic conferenceUtility of 3D echocardiography for valvular heart disease[Invited]Invited oral presentation
- The 5th Annual Scientific Meeting of Japanese Society of Heart Valve Disease, Dec. 2014, Japanese, Japanese Society of Heart Valve Disease, 東京, 症例は56歳男性。突然の構音障害と両下肢脱力を主訴に当院を受診した。頭部MRI検査にて左頭頂葉と右小脳半球に急性期~慢性期の混在した多発性脳梗塞が指摘された。患者は3年前にも同様の下肢脱力発作を認めていたが、症状は一過性であり医療機関は受診していなかった。繰り返す脳梗塞の精査のために心エコー図検査が施行されたところ、僧帽弁A2およびP2の左房側に可動性を有する疣腫を認め、また疣腫による弁尖接合不全とこれに伴う高度の僧帽弁逆流を認めた。臨床所見および血液検査所見上感染所見は皆無であり、また血液培養を繰り返すもすべて陰性であった。その後、先天性血液凝固異常症精査のために行われた免疫血清検査にて、抗リン脂質抗体およびループスアンチコアグラントがともに陽性であることが判明し、原発性抗リン脂質抗体症候群と診断した。僧帽弁に付着する無菌性疣腫は抗リン脂質抗体症候, Domestic conferenceA case of non-infective endocarditis accompanied by multiple cerebral infarction and severe mitral regurgitation as initial presentation of primary antiphospholipid syndromePoster presentation
- American Heart Association Scientific session 2014, Nov. 2014, English, American Heart Association, Cicago, USA, Mid-term RV reverse remodeling after adding PH-specific drugs was associated with long-term outcomes, and this combined approach may well have clinical implications for better management of PH patients., International conferenceCombined Assessment of Right Ventricular Function and Reverse Remodeling as Prognostic Marker after Administration of Medical Treatment for Pulmonary HypertensionPoster presentation
- The 41th Annual Scientific Meeting of the Japan Society of Ultrasonics in Medicine, Nov. 2014, Japanese, Japan Society of Ultrasonics in Medicine, 京都, A 74-year-old male without a history of immunological disorders was transferred to our hospital for further evaluation of persistent high fever in spite of having received optimal antibiotics administration for 13 days. He was diagnosed with bacterial meningitis, and streptococcus agalactiae was identified by the findings of both cerebrospinal fluid culture and blood culture st, Domestic conferenceInfective Endarteritis Associated with Aortic DissectionOral presentation
- The 41th Annual Scientific Meeting of the Japan Society of Ultrasonics in Medicine, Nov. 2014, Japanese, Japan Society of Ultrasonics in Medicine, 京都, Domestic conferenceSevere Aortic Regurgitation Caused by Unicuspid Aortic Based on Quadricuspid valveOral presentation
- American Heart Association Scientific session 2014, Nov. 2014, English, American Heart Association, Chicago, USA, Background: The occurrence of cardiopulmonary exercise testing-derived exercise oscillatory breathing (EOB) is a predictor of survival in heart failure (HF) patients. Whereas, it was recently reported that global circumferential strain (GCS) as assessed by two-dimensional speckle-tracking imaging reflects intrinsic left ventricular (LV) myocardial function and is a powerful pre, International conferenceUtility of Combined Assessment of Exercise Oscillatory Breathing and Global Circumferential Strain to Predict Cardiac Events in Heart Failure PatientsPoster presentation
- American Heart Association Scientific session 2014, Nov. 2014, English, American Heart Association, Chicago, USA, 右房ストレインは血行動態指標と関連しており、肺高血圧症患者の管理において有用である可能性がある。, International conferenceRight Atrial Function as Prognostic factor in Patients with Pulmonary HypertensionPoster presentation
- American Heart Association Scientific session 2014, Nov. 2014, English, American Heart Association, Chicago, USA, Assessment of right ventricular contractile reserve during dobutamine stress offers a significantly better prognostic value for patients with dilated cardiomyopathy. Further, combined assessment of bi-ventricular functional reserve may make a major contribution to better management of these patients., International conferenceIntegrated Assessment of Bi-ventricular Contractile Reserve under Dobutamine Stress Offers an Incremental Prognostic Value for Patients with Dilated CardiomyopathyOral presentation
- American Heart Association Scientific session 2014, Nov. 2014, English, American Heart Association, Chicago, USA, 右室機能と右房リモデリングを組み合わせると、より正確に肺高血圧患者の予後を予測することができる可能性がある。, International conferenceEfficacy of Combining Assessment of Right Ventricular Function and Right Atrial Remodeling as Prognostic Factor in Patients with Pulmonary HypertensionPoster presentation
- 第2回日本肺高血圧学会/第3回日本肺循環学会 合同学術集会, Oct. 2014, Japanese, 日本肺高血圧学会/日本肺循環学会, 東京, Domestic conference先天性心疾患の欠損孔サイズが肺高血圧発症に及ぼす影響評価Oral presentation
- 第2回日本肺高血圧学会/第3回日本肺循環学会 合同学術集会, Oct. 2014, Japanese, 日本肺高血圧学会/日本肺循環学会, 東京, Domestic conference異なる発症機序による体循環-肺循環短絡を伴う肺高血圧症の2例Oral presentation
- The 18th Japanese Heart Failure Society, Oct. 2014, Japanese, 日本心不全学会, 大阪, Domestic conferenceIs Cardiac Resynchronization Theraphy Contraindicated in Heart Failure Patients with A Narrow QRS Complex?Oral presentation
- The 62nd Annual Scientific Session of the Japanese College of Cardiology, Sep. 2014, Japanese, The Japanese College of Cardiology, 仙台, 肺高血圧の薬物治療後中期の右室revers remodelingは長期予後と関連しており、今後肺高血圧治療の管理における指標になる可能性がある。, Domestic conference肺高血圧患者の右室reverse remodelingと長期予後の関連についてOral presentation
- The 62nd Annual ScientificSession of the JapaneseCollege of Cardiology, Sep. 2014, English, Japanese College of Cardiology, 仙台, Domestic conferenceThe authors have no financial conflicts of interest to disclose concerning the presentationOral presentation
- The 62nd Annual Scientific Session of the Japanese College of Cardiology, Sep. 2014, Japanese, The Japanese College of Cardiology, 仙台, Global early diastolic area change rate by 3-dimensional speckle-tracking proved to be dependent on LV relaxation. Moreover, Early diastolic mitral inflow/global early diastolic area change rate was found to be a powerful predictor of LV filling pressure., Domestic conferenceGlobal Endocardial Area Change Rate for the Assessment of Left Ventricular Relaxation and Filling Pressure: Using Three-dimensional Speckle-tracking StudyPublic symposium
- European Society of Cardioglogy Congress 2014, Aug. 2014, English, European Society of Cardioglogy Congress, Barcelona, Spain, TAPSE may be overestimated in PH patients with clockwise rotation resulting from LV compression. TAPSE should thus be evaluated carefully in PH patients with marked apical rotation., International conferenceAssociation of Apical Longitudinal Rotation with Right Ventricular Performance in Patients with Pulmonary Hypertension:Insights into Overestimation of Tricuspid Annular Plane Systolic ExcursionPoster presentation
- Cardiovascular Interventionand Therapeuticsacientific meeting 2014, Jul. 2014, English, 日本心血管インターベンション治療学会, 名古屋, Domestic conferenceThe Mid-term Outcome of Transcatheter Closure of Atrial Septal Defect in the elderlyOral presentation
- American Society of Echocardiography, 25th Annual Scientific Sessions, Jun. 2014, English, American Society of Echocardiography, Portland, USA, Mid-term RV reverse remodeling after adding PH-specific drugs was associated with long-term outcomes, and may well have clinical implications for better management of PH patients., International conferenceAssociation of Right Ventricular Reverse Remodeling with Long-Term Outcomes in Patients with Pulmonary HypertensionPoster presentation
- American Society of Echocardiography, 25th Annual Scientific Sessions, Jun. 2014, English, American Society of Echocardiography, Portland, USA, International conferenceAssociation of Left Atrial Booster-Pump Function with Heart Failure Symptom in Patients with Severe Aortic Stenosis and Preserved Left Ventricular Ejection FractionPoster presentation
- The 87th Annual Scientific Meeting of the Japan Society of Ultrasonics in Medicine, May 2014, Japanese, Japanese Society of Echocardiography, 横浜, 【はじめに】卵円孔は胎生期に形成される心房中隔の開口部で、出生後、呼吸の開始により自然に閉鎖するが、中には成人に達しても自然閉鎖が見られない場合がある。剖検例や経食道心エコー図による検討では成人の約10〜25%認められ、多くの症例は無症状であるが、奇異性塞栓症あるいはplatypnea-orthodeoxia syndromeを来す症例は外科的、経皮的な閉鎖術の適応となる。【症例】約10年前にベトナムから来日した43歳男性で、粟粒結核、心室中隔欠損症の既往がある。2009年頃より労作時の呼吸困難が出現し、仕事の継続が困難となっていた。前医を受診し、低酸素血症を指摘されて精査を行うも、原因を明らかに出来ず経過観察となっていたが、その後も徐々に症状が増悪して日常生活に支障をきたすようになった(NYHA III)ため、精査目的に当院へ紹介となった。安静時室, Domestic conferenceHypoxemia due to patent foramen ovale and tricuspid regurgitationOral presentation
- 日本超音波医学会第87回学術集会, May 2014, Japanese, 日本超音波医学会, 横浜, Domestic conference好酸球増加症における左室心内膜障害の検討Oral presentation
- The 87th Annual Scientific Meeting of the Japan Society of Ultrasonics in Medicine, May 2014, Japanese, Japanese Society of Echocardiography, 横浜, ASD患者に対するカテーテル閉鎖術ではシャント量の少ない患者群でも、シャント量の多い患者群と同等の血行動態の改善が得られた, Domestic conferenceBeneficial Hemodynamic Effect of Transcatheter Closure of Atrial Septum Defect in Patients with Relatively Small ShuntOral presentation
- The 25ths Annual Scientific Meeting of Japanese Society of Echocardiography, Apr. 2014, Japanese, Japanese Society of Echocardiography, 金沢, The role of stress echocardiography for patients with cardiomyopathy is not well established. Thus we will describe the clinical utility and practical method of dobutamine stress echocardiography for these patients., Domestic conferenceDobutamine stress echocardiography for patients with non-ischemic cardiomyopathy ~How to perform?~Public symposium
- The 25th Annual Metting of the Japanese Society of Echocardiography, Apr. 2014, Japanese, Japanese Society of Echocardiography, 金沢, PH患者においては、TAPSEはRV-freeと異なり、収縮期に心尖部が時計回転する患者で過大評価されることが示唆され注意が必要である。, Domestic conference肺高血圧症患者のTAPSE評価におけるlongitudinal apical rotationの影響Oral presentation
- The 25th Annual Metting of the Japanese Society of Echocardiography, Apr. 2014, Japanese, Japanese Society of Echocardiography, 金沢, 近年、大動脈基部拡大を伴った大動脈弁閉鎖不全症に対して自己弁温存基部置換術を行うことが可能となり、本術式を選択される機会も多くなりつつある。これらは現時点では標準術式ではないが、症例数は徐々に増加傾向にあり、従来の弁置換術に劣らない遠隔成績が示されつつある(Oka T, Okita Y, et al. Ann Thorac Surg. 2011;92:1639-45.)。自己弁温存基部置換術を考慮する患者では、術前ならびに術後(術中)の経食道心エコー図検査が極めて有用である。特に大動脈弁複合体の評価と、El Khouryらが提唱している大動脈弁閉鎖不全症のfunctional classificationが重要である(Boodhwani M, El Khoury G. et al. J Thorac Cardiovasc Surg. 2009;137, Domestic conference大動脈基部拡大を伴った大動脈弁閉鎖不全症に対する治療方針-心エコー図で何を見るか?-Public symposium
- The 25th Annual Metting of the Japanese Society of Echocardiography, Apr. 2014, Japanese, Japanese Society of Echocardiography, 金沢, 右室機能は様々な心疾患において予後規定因子であると報告されている。肺高血圧症患者では、右室収縮機能の低下は、独立した予後規定因子であることが多数の研究結果から証明されている。さらに左心不全患者においても、右室収縮機能不全は心血管イベントの発生に強く関与していると報告されている。ゆえに、右心機能を評価することは日常臨床において重要であるが、一筋縄ではいかない。心エコー図法は優れた心機能評価法であるが、右室は左室と異なり形態が複雑であるため、回転楕円体と仮定することはできず、単一断面のトレースから右室容積や右室駆出率を算出することは困難である。この右室の形態の複雑さが、心エコー図法による右室機能の定量的評価を困難にしている。米国心エコー図学会のガイドラインでは、右室収縮能の指標として、三尖弁輪部収縮期移動距離、右室面積変化率、右室弁輪部の長軸方向移動速度, Domestic conference右心機能評価の新技術-スペックルトラッキング法や3次元心エコー図法は右心機能評価に有用か?Public symposium
- The 25th Annual Metting of the Japanese Society of Echocardiography, Apr. 2014, Japanese, Japanese Society of Echocardiography, 金沢, Domestic conferenceSpeckle Tracking 法を用いた抗がん剤による心毒性の早期発見Public symposium
- The 25th Annual Metting of the Japanese Society of Echocardiography, Apr. 2014, Japanese, Japanese Society of Echocardiography, 金沢, 心エコー図法により左室mechanical dyssynchronyの定量評価が可能になり、特に心臓再同期療法(CRT)の反応性が乏しいと予測される症例(非左脚ブロック、QRS幅<150msecなど)に対する、その有用性が報告されている。心エコー図法による左室mechanical dyssynchrony の指標をガイド下に、narrow QRS症例(QRS<130msec)に対するCRTの有用性を検討したEchoCRT(Echocardiography Guided Cardiac Resynchronization Therapy)の結果が最近発表された(N Engl J Med. 2013;369:1395-405.)。結果は散々たるものであり、心エコー図法で左室mechanical dyssynchronyを有すると判断されてCRTを施行され, Domestic conferenceNarrow QRSに対するCRTは禁忌か?Public symposium
- 第25回日本心エコー図学会学術集会, Apr. 2014, Japanese, 日本心エコー図学会, 金沢, Domestic conferenceDuchenne型筋ジストロフィー患者の潜在性左室心筋障害の検出における下肢挙上負荷心エコー図検査の有用性Oral presentation
- The 78th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2014, Japanese, Japanese Circulation Society, 東京, Background: Postoperative atrial fibrillation (POAF) is associated with increased risk of embolic events and heart failure, but its associated factors remains unknown. The purpose of our study was to test the hypothesis that preoperative left atrial (LA) subclinical myocardial dysfunction is a potential predictor of development of POAF in patients with aortic stenosis (AS).Meth, Domestic conferenceLeft Atrial Booster-Pump Function as a Predictive Parameter for New-Onset Postoperative Atrial Fibrillation in Patients with Aortic StenosisPoster presentation
- The 78th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2014, English, Japanese Circulation Society, 東京, Background: Right arterial (RA) pressure has been reported to be a predictor for outcome in pulmonary hypertension (PH) patients, but non-invasive assessment of RA pressure is limited. Our objective was to test the hypothesis that RA volume assessed by two-dimensional echocardiography was correlated with RA pressure by right heart catheterization, and could be a prognostic para, Domestic conferenceImpact of Right Atrial Volume Index as Prognostic Factor in Patients with Pulmonary HypertensionPoster presentation
- The 78th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2014, Japanese, Japanese Circulation Society, 東京, Background: Epicardial left ventricular (LV) pacing is hemodynamically less effective than endocardial LV pacing, whereas high voltage LV coronary sinus pacing decreases QRS duration and inter-ventricular conduction time. Although voltage of coronary sinus pacing has potential to effect the electrical conduction, it is unknown that the associations of voltage of coronary sinus, Domestic conferenceHigh Voltage Coronary Sinus Pacing Improved Left Ventricular Endocardial Function in Heart Failure PatientsPoster presentation
- The 78th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2014, English, Japanese Circulation Society, 東京, Background: The development of right ventricular (RV) dysfunction in patients with pulmonary hypertension (PH) has been associated with adverse outcomes. Right atrial (RA) function could be a prognostic factors as well as RV function, but non-invasive evaluation of RA function is limited. Our objective was thus to test the hypothesis that RA function was associated with hemodyn, Domestic conferenceEvaluation of Right Atrial Function as Potential Prognostic factor in Patients with Pulmonary HypertensionPoster presentation
- The 78th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2014, English, Japanese Circulation Society, 東京, Background: The use of β-blockers has improved the prognosis of dilated cardiomyopathy (DCM). While there are many prognostic predictors, not all of them are applicable to individual patients. Global circumferential strain (GCS) was recently identified as a powerful prognostic marker, which appears to be a better parameter than LV global function for patients with depressed lef, Domestic conferenceEvaluation of Global Circumferential Strain as Prognostic Marker after Administration of β-blockers in Patients with Dilated CardiomyopathyOral presentation
- The 78th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2014, Japanese, Japanese Circulation Society, 東京, Background: The early diastolic mitral inflow and annulus velocities ratio (E/e') were considered as the parameter to estimate left ventricular (LV) filling pressure. According to the guidelines, this parameter is recommended to use for patients with preserved ejection fraction (EF) (≥50%), but not for patients with depressed EF (<50%). A newly developed three-dimen, Domestic conferenceEndocardial Area Change Rate by Three-dimensional Speckle-tracking as an Accurate Predictor of Left Ventricular RelaxationPoster presentation
- American College of Cardiology 63th Annual Scientific Session & Expo, Mar. 2014, English, American College of Cardiology, Washington DC, USA, Background: Left ventricular (LV) dyssynchrony and intrinsic myocardial function are associated with response to cardiac resynchronization therapy (CRT). However, the presence of significant LV dyssynchrony can underestimate echocardiographic assessment of intrinsic LV myocardial function owing to time-phase mismatch contraction.Methods: We studied 131 CRT patients. LV dyssynch, International conferenceEfficacy of Segmental Circumferential Strain Analysis as a Parameter of Intrinsic Left Ventricular Myocardial Function for Cardiac Resynchronization TherapyPoster presentation
- The 78th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2014, English, Japanese Circulation Society, 東京, RV functional reserve as well as LV had significant prognostic impact in patients with DCM. Moreover, combined assessment of bi-ventricular functional reserve may play a key role for better management of such patients., Domestic conferenceCombined Assessment of Bi-ventricular Functional Reserve during Dobutamine Stress Offers a Significant Prognostic Impact for Patients with Dilated CardiomyopathyOral presentation
- The 78th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2014, Japanese, Japanese Circulation Society, 東京, Background: According to the current guidelines for patients with severe aortic stenosis (AS), the management of asymptomatic patients with severe AS and preserved ejection fraction (EF) remains controversial. The aim of this study was thus to assess the association of the development of heart failure symptoms with left atrial (LA) function in patients with severe AS to make us, Domestic conferenceAssociation of Left Atrial Booster-Pump Function with Heart Failure Symptoms in Patients with Severe Aortic Stenosis and Preserved Left Ventricular Ejection FractionPoster presentation
- American College of Cardiology 2013 Scientific Sessions, Mar. 2014, English, American College of Cardiology, Washington DC, USA, PH patients had significant apical counterclockwise rotation, resulting in an inaccurate assessment of TAPSE. RV free-wall longitudinal strain may have a potential clinical implication of more accurate parameter for predicting RV function in such patients., International conferenceAssociation of Apical Longitudinal Rotation with Tricuspid Annular Plane Systolic Excursion in Patients With Pulmonary HypertensionPoster presentation
- EuroEcho-Imaging 2013, Dec. 2013, English, European Association of Cardiovascular Imaging, Istanbul, Turkey, EF significantly decreased from baseline to 6 months and 12 months after anthracycline administration, but E/E' did not., International conferenceTime course of left ventricular myocardial dysfunction by cardiotoxicity of anthracyclinePoster presentation
- EuroEcho-Imaging 2013, Dec. 2013, English, European Association of Cardiovascular Imaging, Istanbul, Turkey, Only 3D-GAS and peak 3D global circumferential strains of the anthracycline group were significantly worse than those of the control group even though global LV systolic and diastolic functions were similar. 3D-GAS correlated significantly with the cumulative doxorubicin dose. It was noteworthy that multivariate analysis showed only 3D-GAS was independently associated with cumu, International conferenceEvaluation of endocardial dysfunction in patients with preserved ejection fraction after anthracycline therapy assessed by three-dimensional speckle tracking strainPoster presentation
- EuroEcho Imaging 2013, Dec. 2013, English, European Association of Cardiovascular Imaging, Istanbul, Turkey, Although, there are some limitations regarding 3D speckle tracking echocardiography, 3D echocardiography has a potential to provide more comprehensive evaluation of LV mechanical Dyssynchrony than was previously possible. So I do believe we should use these two methods complementarily for the assessment of dyssynchrony., International conference3D strain for evaluating left ventricular dyssynchrony[Invited]Nominated symposium
- 日本超音波医学会 第40回関西地方会学術集会, Nov. 2013, Japanese, The Japan Society of Ultrasonics in Medicine, 大阪, 古典的Ehlers-Danlos症候群に合併した稀な高度僧帽弁閉鎖不全症の1例を報告した, Domestic conference古典的Ehlers-Danlos症候群に合併した高度僧帽弁閉鎖不全症の1例Oral presentation
- 日本超音波医学会 第40回関西地方会学術集会, Nov. 2013, Japanese, The Japan Society of Ultrasonics in Medicine, 大阪, 右房に発生したまれな血管肉腫の1例を報告した, Domestic conference右房原発血管肉腫の1例Oral presentation
- American Heart Association Scientific Session 2013, Nov. 2013, English, American Heart Association, Dallas, USA, Background: Left ventricular (LV) dyssynchrony appears to play a major pathophysiologic role in response to cardiac resynchronization therapy (CRT), and intrinsic LV myocardial function is also associated with response. However, the presence of significant LV dyssynchrony can underestimate the assessment of echocardiographic intrinsic LV myocardial function owing to time-phase, International conferenceUtility of Segmental Circumferential Strain Analysis as a Parameter of Intrinsic Left Ventricular Myocardial Function for Cardiac Resynchronization TherapyPoster presentation
- Japanese Society for Heart Valve Disease 2013, Nov. 2013, English, Japanese Society for Heart Valve Disease, 東京, Significant Advances in Transesophageal Echocardiography for Aortic Valve Repair, Domestic conferenceSignificant Advances in Transesophageal Echocardiography for Aortic Valve Repair[Invited]Nominated symposium
- 日本超音波医学会 第41回関西地方会学術集会, Nov. 2013, Japanese, The Japan Society of Ultrasonics in Medicine, 大阪, 症例は31歳男性。健診で肺野異常陰影を指摘され前医にて精査中であった。完全右脚ブロックがあり経胸壁心エコー図にて僧帽弁形態異常を指摘され、無症状ではあったが精査目的にて当科紹介となった。経胸壁心エコー図、および経食道心エコー図における観察では僧帽弁両尖からのびる腱索はすべてが前乳頭筋に収束し、僧帽弁口も側壁側に偏位し、パラシュート僧帽弁を想起させた。しかし扁平で短い低形成の後乳頭筋が存在し、左室自由壁の高位より発生し僧帽弁輪に直接繋がっているように観察された。その他先天性心奇形の合併はなく、CTにおいても上行大動脈拡大、大動脈縮窄症などの合併は認めず、先天性心奇形を合併しないParachute-Like Asymmetric Mitral Valve(PLAMV)の成人例と診断した。PLAMVもパラシュート僧帽弁と同様に先天性の乳頭筋形成不全の1つと, Domestic conferenceParachute-Like Asymmetric Mitral Valveが観察された成人の1症例Oral presentation
- American Heart Association Scientific Session 2013, Nov. 2013, English, American Heart Association, Dallas, USA, Background: Postoperative atrial fibrillation (AF) has been reported to be associated with long-term mortality following aortic valve replacement (AVR), but its associated factors remains unknown. It was recently reported that left atrial (LA) strain rate parameters was associated with the development of AF in prior studies. We therefore used two-dimensional speckle-tracking st, International conferenceLeft Atrial Booster-Pump Function as a Predictive Parameter for New-Onset Postoperative Atrial Fibrillation in Patients with Severe Aortic StenosisPoster presentation
- American Heart Association Scientific Session 2013, Nov. 2013, English, American Heart Association, Dallas, USA, Diminished augmentation of LA reservoir and passive emptying function is closely associated with adverse cardiovascular event., International conferenceLeft Atrial "Reservoir" and "Passive Emptying" Reserve during Dobutamine Stress Have Prognostic Relevance for Patients with Dilated CardiomyopathyOral presentation
- American Heart Association 2013 Scientific Sessions, Nov. 2013, English, American Heart Association, Dallas, USA, LV circumferential myocardial relaxation expressed in Circ-ESR has a potential to show the biventricular condition, and might be a key parameter for better management of PH patients., International conferenceInterdependence in the Biventricle and Its Association with Long-Term Outcome in Patients with Pulmonary HypertensionPoster presentation
- American Heart Association Scientific Session 2013, Nov. 2013, English, American Heart Association, Dallas, USA, Patients who received anthracycline have LV endocardial dysfunction even if global LV function was preserved. Early detection of minor LV myocardial dysfunction may thus play a clinical role in predicting future global LV systolic dysfunction, International conferenceEvaluation of Time Course of Left Ventricular Dysfunction by Cardiotoxicity of AnthracyclinePoster presentation
- The 116th Annual Scientific Meeting of Kinki Regional Office of the Japanese Circulation Society, Nov. 2013, English, Japanese Circulation Society, 大阪, Background: The use of β-blockers has improved the prognosis of dilated cardiomyopathy (DCM). While there are many prognostic predictors, not all of them are applicable to individual patients. Global circumferential strain (GCS) was recently identified as a powerful prognostic marker, which appears to be a better parameter than LV global function for patients with depressed lef, Domestic conferenceEvaluation of Global Circumferential Strain as Prognostic Marker after Administration of β-blockers in Dilated CardiomyopathyOral presentation
- American Heart Association Scientific Session 2013, Nov. 2013, English, American Heart Association, Dallas, USA, Background: The prognosis of dilated cardiomyopathy (DCM) has improved by the use of β-blockers, and the appearance of left ventricular (LV) reverse remodeling is generally thought to result in a favorable prognosis. Although there are many prognostic predictors, they are not sensitive in individual patients. It is recently reported that global circumferential strain (GCS) is a, International conferenceEvaluation of Global Circumferential Strain as Prognostic Marker after Administration of β-blockers for Dilated CardiomyopathyOral presentation
- American Heart Association Scientific Session 2013, Nov. 2013, English, American Heart Association, Dallas, USA, Background: The early diastolic mitral inflow and annulus velocities ratio (E/e') were considered as the parameter to estimate left ventricular (LV) filling pressure. According to the guidelines, this parameter is recommended to use for patients with preserved ejection fraction (EF) (≥50%), but not for patients with depressed EF (<50%). A newly developed three-dimen, International conferenceEndocardial Area Change Rate by Three-dimensional Speckle-tracking as an Accurate Predictor of Left Ventricular RelaxationPoster presentation
- Japanese Society for Heart Valve Disease 2013, Nov. 2013, English, Japanese Society for Heart Valve Disease, 東京, Emerging Role in 3-Dimensional Transesophageal Echocardiography for Aortic Valve Disease, Domestic conferenceEmerging Role in 3-Dimensional Transesophageal Echocardiography for Aortic Valve Disease[Invited]Nominated symposium
- American Heart Association Scientific Session 2013, Nov. 2013, English, American Heart Association, Dallas, USA, Background: Left ventricular (LV) dyssynchrony has emerged as an important mechanism contributing to response to cardiac resynchronization therapy (CRT), but other potential factors, especially LV myocardial viability, can also influence response to CRT. Therefore, an approach combining assessment of LV dyssynchrony and myocardial viability may well be required.Methods: We stud, International conferenceEasy-to-Use Comprehensive Speckle Tracking Evaluation to Minimize Non-Responders Following Cardiac Resynchronization TherapyPoster presentation
- American Heart Association Scientific Session 2013, Nov. 2013, English, American Heart Association, Dallas, USA, Background: According to the current guidelines for patients with severe aortic stenosis (AS), the management of asymptomatic patients with severe AS and preserved ejection fraction (EF) remains controversial. The aim of this study was thus to assess the association of the development of heart failure symptoms with left atrial (LA) function in patients with severe AS to make us, International conferenceAssociation of Left Atrial Booster-Pump Function with Heart Failure Symptoms in Patients with Severe Aortic Stenosis and Preserved Left Ventricular Ejection FractionPoster presentation
- American Heart Association 2013 Scientific Sessions, Nov. 2013, English, American Heart Association, Dallas, USA, Intra RV and inter-ventricular dyssynchrony was associated with RV performance and RV after load, and improved after treatment in PH patients. These indices could have the potential to allow for noninvasive follow-up of such patients., International conferenceAssociation of Inter- and Intra-Ventricular Dyssynchrony with Right Ventricular Performance in Patients with Pulmonary HypertensionPoster presentation
- American Heart Association Scientific Session 2013, Nov. 2013, English, American Heart Association, Dallas, USA, RV functional reserve under dobutamine stress revealed to have a significant prognostic impact in patients with DCM. Moreover, the integrity of both ventricules may play a key role for the favorable outcome in these patients., International conferenceAssessment of Right Ventricular Functional Reserve during Dobutamine Stress Offers a Significant Prognostic Impact for Patients with Dilated CardiomyopathyPoster presentation
- 第61回心臓病学会, Sep. 2013, Japanese, Japanese College of Cardiology, 熊本, Domestic conference肺高血圧症における左室局所心筋拡張能指標の有用性Oral presentation
- 第61回日本心臓病学会学術集会, Sep. 2013, Japanese, 熊本, Domestic conference機能性僧帽弁逆流をもつ慢性重症心不全患者におけるピモベンダン投与の血行動態に与える影響Poster presentation
- 第23回日本心臓核医学会総会, Jun. 2013, Japanese, 日本心臓核医学会, 東京, Domestic conference心臓再同期療法施行患者における治療反応性の有無による99mTc-Tetrofosminのwashout rateの違い:心エコー図検査radial strain法との比較Oral presentation
- American Society Of Echocardiography 24th Annual scientific Sessions, Jun. 2013, English, American Society Of Echocardiography, Minneapolis, U.S.A, Background: Sarcoidosis is a systemic granulomatous disease of undefined cause involving multiple organs. Since cardiac involvement in patients with systemic sarcoidosis leads to substantial morbidity and sudden death, early diagnosis and appropriate management for such patients could be important. Accordingly, the objective of this study was to evaluate left ventricular (LV) s, International conferencePotential Diagnostic Tool of Two-dimensional Speckle-Tracking Strain to Identify Subclinical Myocardial Dysfunction in Patients with Systemic Sarcoidosis with Preserved Ejection FractionPoster presentation
- 日本超音波医学会第86回学術集会, May 2013, Japanese, 日本超音波医学会, 大阪, Domestic conferenceDuchenne型筋ジストロフィーにおける機能的僧帽弁閉鎖不全症と僧帽弁形態についてOral presentation
- The 72nd Annual Meeting of the Japan Radiological Society, Apr. 2013, Japanese, The Japan Radiological Society, 横浜, Domestic conferenceMRI Findings of Cardiac AmyloidosisOral presentation
- The 35th Annual Meeting of the Japan Society for Hematopoietic Cell Transplantation, Mar. 2013, Japanese, The Japan Society for Hematopoietic Cell Transplantation, 金沢, Domestic conferenceステロイド治療が著効したリンパ球浸潤を伴わない心GVHDPoster presentation
- The 77th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2013, English, Japanease Circulation Society, 横浜, RV-free has the potential to allow for noninvasive follow-up of patients with distal-type CTEPH referred for PTPA., Domestic conferenceUtility of Right Ventricular Free Wall Longitudinal Speckle-Tracking Strain for Detecting Right Ventricular Performance after Percutaneous Transluminal Pulmonary AngioplastyOral presentation
- The 77th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2013, Japanese, Japanease Circulation Society, 横浜, Non-invasively assessed RA volume index index was associated with RA pressure and long-term outcome in PH patients., Domestic conferencePrognostic Value of Right Atrial Volume Index and Its Association of Right Atrial Pressure in Patients with Pulmonary HypertensionPoster presentation
- The 77th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2013, English, Japanease Circulation Society, 横浜, Reduced augmentation of left atrial functional reserve during dobutamine stress demonstrated strong association with cardiovascular event., Domestic conferenceLeft Atrial Functional Reserve in "Reservoir" and "Passive Emptying" during Dobutamine Stress Has an Impact on Cardiac Events in Patients with Dilated CardiomyopathyOral presentation
- The 77th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2013, Japanese, Japanease Circulation Society, 横浜, Impact of Right Ventricular Geometry on Mitral Regurgitation after Transcatheter Closure of Atrial Septal Defect, Domestic conferenceImpact of Right Ventricular Geometry on Mitral Regurgitation after Transcatheter Closure of Atrial Septal DefectOral presentation
- The 77th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2013, English, Japanease Circulation Society, 横浜, We demonstrated that dynamic dyssynchrony during dobutamine stress constitutes a potential predictor of cardiovascular events in heart failure patients with dilated cardiomyopathy, and the assessment of dynamic dyssynchrony combined with that of contracti, Domestic conferenceImpact of Dynamic Dyssynchrony Assessed by Three-Dimensional Speckle-Tracking Area Strain during Dobutamine Stress on Cardiovascular Events in Patients with Dilated CardiomyopathyOral presentation
- The 77th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2013, English, Japanease Circulation Society, 横浜, 3-D speckle-tracking area strain was found to be useful for evaluating subtle endocardial dysfunction associated with anthracyclines, Domestic conferenceEndocardial Dysfunction in Patients with Preserved Ejection Fraction After Anthracycline Therapy Using Three-Dimensional Speckle-Tracking Area StrainPoster presentation
- American College of Cardiology Annual Scientific Session 2013, Mar. 2013, English, American College of Cardiology, San Francisco, CA, 3-D speckle-tracking area strain was found to be useful for evaluating subtle endocardial dysfunction associated with anthracyclines, International conferenceEndocardial Dysfunction in Patients with Preserved Ejection Fraction after Anthracycline Therapy as Assessed by Three-Dimensional Speckle-TrackingArea StrainPoster presentation
- The 77th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2013, Japanese, Japanease Circulation Society, 横浜, 三次元スペックルトラッキング法を用いた左室拡張指標が左室充満圧を予測できることを報告した, Domestic conferenceEndocardial Area Change Rate by Three-dimensional Speckle-tracking Predicts Left Ventricular Filling Pressures in Heart Failure Patients with Depressed Ejection FractionPoster presentation
- American College of Cardiology Annual Scientific Session 2013, Mar. 2013, English, American College of Cardiology, San Francisco, CA, Easy-to-use combined speckle-tracking approach from the same view may well have clinical implications for better management of CRT patients., International conferenceEasy-to-Use Comprehensive Speckle Tracking Approach to Minimize Non-Responders to Cardiac Resynchronization TherapyPoster presentation
- The 77th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2013, English, Japanease Circulation Society, 横浜, 心臓再同期療法による左室拡張能の急性改善が治療後の予後を予測することを三次元スペックルトラッキング法を用いて報告した, Domestic conferenceEarly Diastolic Area Change Rate by Three-dimensional Speckle Tracking Predicts Left Ventricular Reverse-Remodeling and Long-Term Outcome following Cardiac Resynchronization TherapyOral presentation
- The 77th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2013, English, Japanease Circulation Society, 横浜, Three dimensional global circumferential strain with dobutamine stress would have potential to predict cardiovascular events in heart failure patients with dilated cardiomyopathy., Domestic conferenceContractile Reserve Assessed by Three-Dimensional Global Circumferential Speckle-Tracking Strain as a Predictor of Cardiovascular Events in Patients with Idiopathic Dilated CardiomyopathyOral presentation
- The 77th Annual Scientific Meeting of the Japanese Circulation Society, Mar. 2013, English, Japanease Circulation Society, 横浜, 2次元スペックルトラッキング法により左室短軸像乳頭筋レベルの拡張早期のCircumferencial strain rateを用いて肺高血症患者の予後を推定しえた。また、同指標は右室収縮能・左室拡張指標とも相関した。, Domestic conferenceAssociation of Left Ventricular Myocardial Early Diastolic Motion with Long-Term Outcome in Patients with Pulmonary HypertensionPoster presentation
- The 15th annual meeting of Japanease Society of Adult Congenital Heart Disease, Jan. 2013, Japanese, Japanease Society of Adult Congenital Heart Disease, 東京, Ebstein奇形を合併したTRにドブタミン負荷エコーが右室機能を評価するのに有用であった。, Domestic conference肝硬変及び難治性心不全を呈した高齢Ebstein奇形に対して、外科的治療が奏効した一例Poster presentation
- 33rd Annual Scientific Meeting of the Korean Society of Echocardiography, Dec. 2012, English, Korean Society of Echocardiography, Seoul, Korea, 3次元speckle tracking法の有用性を報告した, International conferenceEmerging Role of Three Dimensional Speckle Tracking Strain for Accurate Quantification of Left Ventricular Dyssynchrony[Invited]Invited oral presentation
- American Heart Association Scientific Session 2012, Nov. 2012, English, American Heart Association, Los Angeles, CA, narrow QRSの心不全患者においても左室同期不全が存在することを報告した, International conferenceFeature of Mechanical Left Ventricular Dyssynchrony in Heart Failure Patients with "Very" Narrow QRS Duration: Using Three-dimensional Speckle-tracking StudyPoster presentation
- American Heart Association Scientific Session 2012, Nov. 2012, English, American Heart Association, Los Angeles, CA, We demonstrated that dynamic dyssynchrony during dobutamine stress constitutes a potential predictor of cardiovascular events in heart failure patients with dilated cardiomyopathy, and the assessment of dynamic dyssynchrony combined with that of contracti, International conferenceDynamic Left Ventricular Dyssynchrony Assessed by Three-Dimensional Speckle-Tracking Area Strain during Dobutamine Stress Has a Negative Impact on Cardiovascular Events in Patients with Idiopathic Dilated CardiomyopathyOral presentation
- American Heart Association Scientific Session 2012, Nov. 2012, English, American Heart Association, Los Angeles, CA, Non-invasively assessed right arterial volume was associated with right atrial pressure by hemodynamic measurement in PH patients., International conferenceCorrelation between Right Arterial Pressure and Right Arterial Volume Index in Patients with Pulmonary HypertensionPoster presentation
- American Heart Association Scientific Session 2012, Nov. 2012, English, American Heart Association, Los Angeles, CA, Three dimensional global circumferential strain with dobutamine stress would have potential to predict cardiovascular events in heart failure patients with dilated cardiomyopathy., International conferenceContractile Reserve Assessed by Three-Dimensional Global Circumferential Strain as a Predictor of Cardiovascular Events in Patients with Idiopathic Dilated CardiomyopathyOral presentation
- American Heart Association Scientific Session 2012, Nov. 2012, English, American Heart Association, Los Angeles, CA, 心臓再同期療法によるStrain Dyssynchrony Indexの急性期減少が治療後の長期予後を予測することを報告した, International conferenceAcute Reduction in Strain Dyssynchrony Index with Cardiac Resynchronization Therapy Predicts Mid-Term Left Ventricular Reverse-remodeling and Long-Term Outcome: Using Two-dimensional Speckle-tracking StudyOral presentation
- American Heart Association Scientific Session 2012, Nov. 2012, English, American Heart Association, Los Angeles, CA, 右室自由壁のLongitudinalの2次元スペックルトラッキング法を用いて肺高血症患者の予後を推定しえた。また同指標に右室収縮機能の指標であるTAPSEを加えることにより精度が増すことも報告した。, International conferenceAbility of Right Ventricular Free Wall Longitudinal Speckle-Tracking Strain for Predicting Long-term Outcome in Patients with Pulmonary HypertensionOral presentation
- The 5th Asia Pacific Heart Rhythm Society Scientific Session, Oct. 2012, English, Asia Pacific Heart Rhythm Society, Tipei, Tiwan, 三次元スペックルトラッキング法を用いた左室同期不全についてreviewした, International conferenceEvaluation of Left Ventricular Function and Mechanical Dyssynchrony: Using Three-dimensional Speckle-tracking Strain[Invited]Invited oral presentation
- The 60th Annual Scientific Sessiion of the Japanese College of Cardiology, Sep. 2012, Japanese, The Japanese College of Cardiology, 金沢, 右室自由壁のLongitudinalの2次元スペックルトラッキング法を用いて肺高血症患者の予後を推定しえた。, Domestic conference肺動脈性高血圧症患者の長期予後予測における右室自由壁スペックルトラッキング法の有用性Oral presentation
- The 60th Annual Scientific Sessiion of the Japanese College of Cardiology, Sep. 2012, Japanese, The Japanese College of Cardiology, 金沢, 重症大動脈弁閉鎖不全症に対する手術適応の検討と手術術式の決定における経食道心エコー図検査の役割をreviewした, Domestic conference重症大動脈弁閉鎖不全症に対する手術適応の検討と手術術式の決定における経食道心エコー図検査の役割Public symposium
- The 60th Annual Scientific Sessiion of the Japanese College of Cardiology, Sep. 2012, Japanese, The Japanese College of Cardiology, 金沢, 左室同期不全と心臓交感神経活性との関連性を報告した, Domestic conference左室同期不全が慢性心不全患者の心臓交感神経活性に及ぼす影響と心臓再同期療法の効果予測についてPublic symposium
- Japanese Pulmonary Circulation Society, 1st Scientific Meeting, Sep. 2012, Japanese, Japanese Pulmonary Circulation Society, 東京, 肺高血圧症患者における運動負荷試験の有用性を報告した, Domestic conferenceAbility of cardiopulmonary exercise testing for assessing exercise capacity in patients with pulmonary arterial hypertension and normal lower limb muscle strength in comparison with 6-min walking testOral presentation
- 29th Korea-Japam Urological Congress, Sep. 2012, English, Korea-Japam Urological Congress, 鹿児島, International conferencePrognostic significance of primary Gleason pattern in Japanese men with Gleason score 7 prostate cancer treated with radical prostatectomyOral presentation
- American Society of Echocardiography 23th Annual Scientific Session, Jul. 2012, English, American Society of Echocardiography, Washington, DC, 3D心エコー図検査と心臓CTで左房の径、容積等を比較検討した, International conferenceComparison of Left Atrial Size Measured by Various Echocardiographic Approaches with That Measured by Multidetector Computed TomographyPoster presentation
- American Society of Echocardiography 23th Annual Scientific Session, Jun. 2012, English, American Society of Echocardiography, Washington, DC, 右室自由壁のLongitudinalの2次元スペックルトラッキング法を用いて肺高血症患者の予後を推定しえた。, International conferenceEfficacy of Right Ventricular Free Wall Longitudinal Speckle-Tracking Strain for Predicting Long-term Outcome in Patients with Pulmonary HypertensionPoster presentation
- The 85th Annual Scientific Meeting of the Japan Society of Ultrasonics in Medicine, May 2012, Japanese, The Japan Society of Ultrasonics in Medicine, 東京, 大動脈二尖弁に合併した大動脈縮窄症の1例を症例報告した, Domestic conferenceMultiple regions of coarctation of the aorta associated with bicuspid aortic valve in a 74-year-old femalePoster presentation
- The 85th annual scientific meeting of the Japan Society of Ultrasonics in Medicine, May 2012, Japanese, The Japan Society of Ultrasonics in Medicine, 東京, 【目的】心臓再同期療法(CRT)の効果を予測する際には、CRT前の左室dyssynchronyの評価が検討されてきたが、単一の指標のみでは十分ではない。一方、CRT植え込み後急性期の左室dyssynchronyの指標とCRTの効果を検討した研究は少ない。本研究の目的は、CRT施行急性期における左室dyssynchronyの改善と長期予後との関係、またCRT前の左室dyssynchronyの指標とCRT施行急性期におけるその改善度を組み合わせる事で、CRTの長期予後をより正確に予測できるかどうかを検討することである。【方法】CRTを施行した重症心不全患者121例(平均左室駆出率27±6%、平均QRS幅164±24ms、虚血性心疾患30例)を対象として、CRT前とCRT施行急性期(7±3日後)に心エコー図検査を施行した。左室dyssynchronyは2次, Domestic conference心臓再同期療法前と施行急性期における左室同期不全の指標を用いた長期予後の検討Oral presentation
- The 85th Annual Scientific Meeting of the Japan Society of Ultrasonics in Medicine, May 2012, Japanese, The Japan Society of Ultrasonics in Medicine, 東京, CRT]患者に合併する僧帽弁閉鎖不全症のメカニズムを奉公した, Domestic conferenceRelation Between Left Ventricular Morphology and Reduction in Functional Mitral Regurgitation by Cardiac Resynchronization TherapyPublic symposium
- The 85th annual scientific meeting of the Japan Society of Ultrasonics in Medicine, May 2012, Japanese, The Japan Society of Ultrasonics in Medicine, 東京, 左室全体の機能が保たれるが、アントラサイクリン系薬剤使用により左室心内膜障害が認められることが、3次元スペックルトラッキング法によるArea strainを用いて観察された, Domestic conferenceEndocardial Dysfunction in Patients with Preserved Ejection Fraction After Anthracycline Therapy by Three-Dimensional Speckle-Tracking Strain ImagingOral presentation
- The 85th Annual Scientific Meeting of the Japan Society of Ultrasonics in Medicine, May 2012, Japanese, The Japan Society of Ultrasonics in Medicine, 東京, Duchene型筋疾患患者に合併する僧帽弁閉鎖不全症のメカニズムを奉公した, Domestic conferenceRelationship between functional mitral regurgitation and left atrial size in Duchenne Muscular DystrophyOral presentation
- The 85th annual scientific meeting of the Japan Society of Ultrasonics in Medicine, May 2012, Japanese, The Japan Society of Ultrasonics in Medicine, 東京, wide QRS患者に多い左室同期不全がnarrow QRS患者にも存在することを報告した, Domestic conference3次元スペックルトラッキング法を用いた左室同期不全評価-wideからnarrow QRSまで-Public symposium
- The 23th annual meeting of the Japanease Society of Echocardiography, Apr. 2012, Japanese, Japanease Society of Echocardiography, 大阪, 二次元スペックルトラッキング法により算出された右室自由壁ストレインは肺高血圧症患者において非侵襲的な指標になりうる。, Domestic conference肺高血症患者における右室2次元スペックルトラッキング法の有用性Oral presentation
- The 23th annual meeting of the Japanease Society of Echocardiography, Apr. 2012, Japanese, Japanease Society of Echocardiography, 大阪, 僧帽弁閉鎖不全症の心エコー図法の評価のしかたならびに有用性をreviewした, Domestic conference僧帽弁逆流の定量化の必要性と問題点[Invited]Nominated symposium
- The 23th annual meeting of the Japanease Society of Echocardiography, Apr. 2012, Japanese, Japanease Society of Echocardiography, 大阪, 肺静脈波形による左房機能と肺静脈拡大の心房細動発症への関与を検討した, Domestic conference心房細動患者における左房機能と肺静脈リモデリングの関係Public symposium
- The 23th annual meeting of the Japanease Society of Echocardiography, Apr. 2012, Japanese, Japanease Society of Echocardiography, 大阪, 様々な心疾患に対する右室機能の重要性をreviewした, Domestic conference心不全における心機能指標の見方 右室機能[Invited]Nominated symposium
- The 23th annual meeting of the Japanease Society of Echocardiography, Apr. 2012, Japanese, Japanease Society of Echocardiography, 大阪, 急性心筋梗塞に合併する様々な致死的疾患をreviewした, Domestic conference急性心筋梗塞の合併症診断[Invited]Nominated symposium
- The 23th annual meeting of the Japanease Society of Echocardiography, Apr. 2012, Japanese, Japanease Society of Echocardiography, 大阪, 【症例】66歳男性。既往歴に糖尿病がある。2011年9月12日に呼吸困難が出現し、胸部X線にて肺うっ血を認め、急性心不全の診断で近医入院となった。しかし、酸素吸入とカテコラミンや利尿剤の持続投与を行うも、症状や心機能の改善は認められなかったため、9月21日に当院に転院となった。当院入院時は左室拡張末期径52mm、左室収縮末期径46mm、左室駆出率は25%と左室収縮能は高度に障害されていた。びまん性の左室壁障害を認め、壁の菲薄化や瘤などは認められなかった。冠動脈に有意狭窄はなかった。また、右室心筋から非乾酪性類上皮細胞肉芽腫の所見が得られ、心臓MRIでは心室中隔の右室側、前部中隔接合部~右室および左室下壁にかけて遅延造影が認められた。以上の結果から心サルコイドーシスと診断した。FDG-PETでは、前後部中隔接合部、左室側壁、および右室の一部でFDGの集, Domestic conference急性の経過を呈した心サルコイドーシスの一例Oral presentation
- The 23th annual meeting of the Japanease Society of Echocardiography, Apr. 2012, Japanese, Japanease Society of Echocardiography, 大阪, 3か月の経過で急激に心機能が低下した稀な小児のミトコンドリア心筋症の症例を報告した, Domestic conference急激に悪化した小児ミトコンドリア心筋症の一例Oral presentation
- The 23th annual meeting of the Japanease Society of Echocardiography, Apr. 2012, Japanese, Japanease Society of Echocardiography, 大阪, 右室自由壁のLongitudinalの2次元スペックルトラッキング法を用いて肺高血症患者の予後を推定しえた。, Domestic conference右室スペックルトラッキング法による肺高血圧症患者の長期予後予測の検討Public symposium
- The 23th annual meeting of the Japanease Society of Echocardiography, Apr. 2012, Japanese, Japanease Society of Echocardiography, 大阪, CRTに対する心エコー図法の有用性ならびにclinical implicationsを提示した, Domestic conferenceCRT症例検討会pre-review[Invited]Nominated symposium
- The 23th annual meeting of the Japanease Society of Echocardiography, Apr. 2012, Japanese, Japanease Society of Echocardiography, 大阪, Contractile Reserve by Three-Dimensional Global Circumferential Strain can Predict Outcome in Dilated Cardiomyopathy, Domestic conferenceContractile Reserve by Three-Dimensional Global Circumferential Strain can Predict Outcome in Dilated CardiomyopathyOral presentation
- The 23th annual meeting of the Japanease Society of Echocardiography, Apr. 2012, Japanese, Japanease Society of Echocardiography, 大阪, Acute Effects of Adaptive Servo-Ventilation Therapy on Left Ventricular Regional Myocardial Function, Domestic conferenceAcute Effects of Adaptive Servo-Ventilation Therapy on Left Ventricular Regional Myocardial FunctionOral presentation
- The 23th annual meeting of the Japanease Society of Echocardiography, Apr. 2012, Japanese, Japanease Society of Echocardiography, 大阪, 3次元speckkle tracking法のCRTへの有用性を報告した, Domestic conference3DTならではの功を奏したdyssynchrony評価の例[Invited]Nominated symposium
- The 23th annual meeting of the Japanease Society of Echocardiography, Apr. 2012, Japanese, Japanease Society of Echocardiography, 大阪, 右脚ブロック型のwide QRS症例は、左脚ブロック型の症例と比較して心臓再同期療法(CRT)により心機能が改善する確率が低く、その適応を見極めるのは容易ではない。今回2次元スペックルトラッキング法がCRTの適応に有用であった右脚ブロック型wide QRSの症例を提示する。78歳男性。虚血性心筋症にて内服加療をされていたが、心不全による入退院を繰り返していた。NYHAはIII°、心電図はQRS幅140msの完全右脚ブロックを呈しており、左室駆出率は23%と高度に低下していた。2次元スペックルトラッキング法による、左室短軸像心室中部レベルの前部中隔と後壁のpeak radial strainの時間差が425ms(≧130ms)と有意な左室のmechanical dyssynchronyを認めたため、CRTを施行した。CRT施行1週間後には左室駆出率は2, Domestic conference2次元スペックルトラッキング法が心臓再同期療法の適応に有用であった右脚ブロック型wide QRSの1症例Oral presentation
- American College of Cardiology Scientific Session 2012, Mar. 2012, English, American College of Cardiology, シカゴ, 米国, International conferenceUtility of Combined Assessment of Baseline Dyssynchrony and Its Acute Improvement to Predict Long-Term Outcome after Cardiac Resynchronization TherapyPoster presentation
- 第76回日本循環器病学会学術集会, Mar. 2012, English, 日本循環器病学会, 福岡, International conferenceSubendocardial Dysfunction in Patients with Chronic Severe Aortic Regurgitation and Preserved Ejection Fraction Using Speckle-Tracking Strain and Transmural Strain ProfileOral presentation
- 第76回日本循環器病学会学術集会, Mar. 2012, English, 日本循環器病学会, 福岡, International conferenceLeft Ventricular Mechanical Dyssynchrony in Heart Failure Patients with "Very" Narrow QRS Duration: Using Three-dimensional Speckle-tracking StudyOral presentation
- 第76回日本循環器病学会学術集会, Mar. 2012, English, 日本循環器病学会, 福岡, International conferenceLeft Ventricular Dyssynchrony as a Determinant of Torsional Mechanics in Patients with Dilated CardiomyopathyOral presentation
- 第76回日本循環器病学会学術集会, Mar. 2012, English, 日本循環器病学会, 福岡, International conferenceImpact of Left Ventricular Dyssynchrony on Cardiac Sympathetic Activity in Heart Failure Patients Following Cardiac Resynchronization TherapyOral presentation
- American College of Cardiology Scientific Session 2012, Mar. 2012, English, American College of Cardiology, シカゴ, 米国, International conferenceEvaluation of Left Ventricular Filling Pressures Using Tissue Doppler Derived Myocardial Acceleration During Isovolumic ContractionPoster presentation
- 第76回日本循環器病学会学術集会, Mar. 2012, Japanese, 日本循環器病学会, 福岡, International conferenceDetection of Subclinical Myocardial Dysfunction in Patients with Sarcoidosis Using Three-Dimensional Speckle Tracking StrainPoster presentation
- 第76回日本循環器病学会学術集会, Mar. 2012, English, 日本循環器病学会, 福岡, International conferenceComparison of Left Atrial Size Measured by Various Echocardiographic Approaches with That Measured by Multidetector Computed TomographyPoster presentation
- 第76回日本循環器病学会学術集会, Mar. 2012, English, 日本循環器病学会, 福岡, International conferenceAssociation of Acute Reduction in Strain Dyssynchrony Index with Mid-Term Left Ventricular Reverse Remodeling and Long-Term Outcome after Cardiac Resynchronization TherapyOral presentation
- 第76回日本循環器病学会学術集会, Mar. 2012, Japanese, 日本循環器病学会, 福岡, International conferenceAssociation of Acute Improvement in Left Ventricular Dyssynchrony with Long-Term Outcome after Cardiac Resynchronization TherapyPoster presentation
- 第76回日本循環器病学会学術集会, Mar. 2012, Japanese, 日本循環器病学会, 福岡, International conferenceAcute Effects of Adaptive Servo-Ventilation Therapy on Left Ventricular Regional Myocardial Function in Heart Failure PatientsPoster presentation
- American College of Cardiology Scientific Session 2012, Mar. 2012, English, American College of Cardiology, シカゴ, 米国, International conferenceAbility of Contractile Reserve Assessed by Three-Dimensional Global Circumferential Strain as a Predictor of Long-Term Outcome in Patients with Idiopathic Dilated CardiomyopathyPoster presentation
- 日本超音波医学会 第39回関西地方会学術集会, Nov. 2011, Japanese, 日本超音波医学会, 大阪, Domestic conference当院で経験した大動脈四尖弁の4症例Oral presentation
- 日本超音波医学会 第39回関西地方会学術集会, Nov. 2011, Japanese, 日本超音波医学会, 大阪, Domestic conference初回手術から11年後に発症したステントレス生体弁機能不全による急性大動脈弁閉鎖不全症の1例Oral presentation
- 日本超音波医学会 第39回関西地方会学術集会, Nov. 2011, Japanese, 日本超音波医学会, 大阪, Domestic conference一酸化炭素中毒を契機に一過性の壁運動異常を呈した1 例Oral presentation
- 第112回日本循環器病学会近畿地方会, Nov. 2011, Japanese, 日本循環器病学会, 京都, Domestic conferenceステロイドが奏功した抗ミトコンドリアM2抗体関連多発性筋炎に合併した慢性心筋炎の1例Oral presentation
- American Heart Association Scientific Sessions 2011, Nov. 2011, English, フロリダ, アメリカ, International conferenceUtility of Transmural Myocardial Strain Profile to Predict Early Left Ventricular Dysfunction in Patients with Duchenne Muscular Dystrophy.Poster presentation
- American Heart Association Scientific Session 2011, Nov. 2011, English, American Heart Association, シカゴ, 米国, International conferenceUtility of Transmural Myocardial Strain Profile to Predict Early Left Ventricular Dysfunction in Patients with Duchenne Muscular DystrophyOral presentation
- American Heart Association Scientific Session 2011, Nov. 2011, English, American Heart Association, シカゴ, 米国, International conferenceUtility of Three-Dimensional Speckle Tracking Radial Strain for Identifying Patients with Cardiac SarcoidosisPoster presentation
- American Heart Association Scientific Session 2011, Nov. 2011, English, American Heart Association, シカゴ, 米国, International conferenceRegional Heterogeneity of Systolic Dysfunction Leads to Ventricular Dyssynchrony in Patients with Idiopathic Dilated Cardiomyopathy and Narrow QRS Complex; 3-Dimensional Speckle-Tracking Strain AnalysisOral presentation
- American Heart Association Scientific Session 2011, Nov. 2011, English, American Heart Association, シカゴ, 米国, International conferenceMultidirectional Left Ventricular Performance Using Three-Dimensional Speckle-Tracking Strain in Patients with Chronic Right Ventricular Pacing and Preserved Ejection FunctionOral presentation
- American Heart Association Scientific Session 2011, Nov. 2011, English, American Heart Association, シカゴ, 米国, International conferenceLeft Ventricular Dyssynchrony as a Determinant of Torsional Mechanics in Patients with Dilated CardiomyopathyPoster presentation
- American Heart Association Scientific Session 2011, Nov. 2011, English, American Heart Association, シカゴ, 米国, International conferenceEndocardial Dysfunction in Patients with Chronic Aortic Regurgitation and Preserved Ejection FractionPoster presentation
- American Heart Association Scientific Session 2011, Nov. 2011, English, American Heart Association, シカゴ, 米国, International conferenceAbility of Comprehensive Assessment of Strain Dyssynchrony Index by Speckle Tracking Imaging to Predict Long-Term Outcome after Cardiac Resynchronization Therapy in Patients with Heart FailurePoster presentation
- 第59回日本心臓病学会学術集会, Sep. 2011, Japanese, 日本心臓病学会, 神戸, Domestic conference心臓再同期療法における3次元スペックルエリアトラッキング法の有用性Public symposium
- 第59回日本心臓病学会学術集会, Sep. 2011, Japanese, 日本心臓病学会, 神戸, Domestic conference左室駆出率の低下したnarrow QRS心不全患者にも左室同期不全は存在する −3次元スペックルトラッキング法を用いた検討−Public symposium
- 第59回日本心臓病学会学術集会, Sep. 2011, Japanese, 日本心臓病学会, 神戸, Domestic conference抗ミトコンドリアM2抗体関連多発性筋炎に合併した慢性心筋炎の1例Poster presentation
- European Society of Cardiology National Meeting 2011, Aug. 2011, English, European Society od cardiology, パリ, フランス, International conferenceReverse remodeling induces progressive resynchronization after cardiac resynchronization therapy: from vicious to virtuous cycleOral presentation
- 第111回日本循環器病学会近畿地方会, Jun. 2011, Japanese, 日本循環器病学会, 神戸, Domestic conferenceカルチノイド症候群に合併した高度肺動脈弁閉鎖不全症および三尖弁閉鎖不全症の1症例Oral presentation
- American Society of Echocardiography National Meeting 2011, Jun. 2011, English, American Society of Echocardiography, モントリオール, カナダ, International conferenceMultidirectional Left Ventricular Performance Using Three-Dimensional Speckle-Tracking Strain in Patients with Chronic Right Ventricular Pacing and Preserved Ejection FunctionOral presentation
- American Society of Echocardiography National Meeting 2011, Jun. 2011, English, American Society of Echocardiography, モントリオール, カナダ, International conferenceImpact of Left Ventricular Afterload on Left Ventricular Longitudinal Dyssynchrony in Patients with Severe Aortic Valve StenosisPoster presentation
- 第111回日本循環器病学会近畿地方会, Jun. 2011, Japanese, 日本循環器病学会, 神戸, Domestic conference3次元経食道心エコー図が診断に有用であったUnicommissural Unicuspid Aortic Valve Stenosisの一例Oral presentation
- 日本超音波医学会第84回学術集会, May 2011, Japanese, 日本超音波医学会, 東京, Domestic conferenceA case of thrombus through a patent foramen ovale complicated by acute pulmonary thromboembolismPoster presentation
- 日本超音波医学会第84回学術集会, May 2011, Japanese, 日本超音波医学会, 東京, Domestic conferenceUtility of Three-Dimensional Speckle-Tracking System for Cardiac Resynchronization TherapyOral presentation
- 日本超音波医学会第84回学術集会, May 2011, Japanese, 日本超音波医学会, 東京, Domestic conferenceA Case of Nonbacterial Thrombotic Endocarditis Associated with Cancer of Unknown Origin Complicated with Thrombus in the Left Auricular AppendageOral presentation
- 日本超音波医学会第84回学術集会, May 2011, Japanese, 日本超音波医学会, 東京, Domestic conferenceUsefulness of longitudinal speckle tracking strain with handgrip and Dobutamine stress for identifying ischemic myocardial segments In patients with angina pectorisOral presentation
- 第22回日本心エコー図学会学術集会, Apr. 2011, Japanese, 日本心エコー図学会, 鹿児島, Domestic conference心サルコイドーシスの診断における3次元スペックルトラッキング法の有用性Poster presentation
- 第22回日本心エコー図学会学術集会, Apr. 2011, Japanese, 日本心エコー図学会, 鹿児島, Domestic conference左室正常壁運動のDuchenne型筋ジストロフィーにおけるradial strain中に見られたノッチの臨床的意義についてOral presentation
- 第22回日本心エコー図学会学術集会, Apr. 2011, Japanese, 日本心エコー図学会, 鹿児島, Domestic conference左室Dyssynchronyの評価における2-Dおよび3-D Speckle Tracking法の有用性Invited oral presentation
- 第22回日本心エコー図学会学術集会, Apr. 2011, Japanese, 日本心エコー図学会, 鹿児島, Domestic conference高度三尖弁閉鎖不全と右室機能低下を伴ったEbstein奇形の術後の予後予測にドブタミン負荷心エコー法が有用であった1例Poster presentation
- 第22回日本心エコー図学会学術集会, Apr. 2011, Japanese, 日本心エコー図学会, 鹿児島, Domestic conference経胸壁心エコー図法を用いた大動脈弁置換術における適切な人工弁サイズの推測方法に関する検討Poster presentation
- 第22回日本心エコー図学会学術集会, Apr. 2011, Japanese, 日本心エコー図学会, 鹿児島, Domestic conference拡張型心筋症における左室収縮能障害の不均一性と左室同期不全との関係 3D Speckle-Tracking 法を用いた定量化の試みOral presentation
- 第22回日本心エコー図学会学術集会, Apr. 2011, Japanese, 日本心エコー図学会, 鹿児島, Domestic conferenceスペックルトラッキング法を用いた慢性大動脈弁閉鎖不全症患者における局所心筋機能評価の有用性Oral presentation
- 第22回日本心エコー図学会学術集会, Apr. 2011, Japanese, 日本心エコー図学会, 鹿児島, Domestic conferenceカルチノイド症候群に合併した高度肺動脈弁閉鎖不全症および三尖弁閉鎖不全症の1症例Oral presentation
- 第22回日本心エコー図学会学術集会, Apr. 2011, Japanese, 日本心エコー図学会, 鹿児島, Domestic conference2D、3D Speckle TrackingによるCRT評価の実際Invited oral presentation
- 第75回日本循環器学会総会・学術集会, Mar. 2011, English, 日本循環器学会, 横浜, Domestic conferenceUsefulness of Right Ventricular Speckle Tracking Strain to Evaluate the Effect of Medical Treatment in Patients with Pulmonary HypertensionOral presentation
- 第75回日本循環器学会総会・学術集会, Mar. 2011, Japanese, 日本循環器学会, 横浜, Domestic conferenceThe usefulness of longitudinal speckle tracking strain with handgrip stress to detect ischemic myocardial segmentsPoster presentation
- 第75回日本循環器学会総会・学術集会, Mar. 2011, English, 日本循環器学会, 横浜, Domestic conferenceRegional Heterogeneity of Systolic Dysfunction Leads to Ventricular Dyssynchrony in Patients with Dilated Cardiomyopathy and Narrow QRS Complex Assessed by 3-Dimensional Speckle-Tracking StrainOral presentation
- 第75回日本循環器学会総会・学術集会, Mar. 2011, English, 日本循環器学会, 横浜, Domestic conferenceMultidirectional Left Ventricular Performance Using Three-Dimensional Speckle-Tracking Strain in Patients with Chronic Right Ventricular Pacing and Preserved Ejection FunctionOral presentation
- 第75回日本循環器学会総会・学術集会, Mar. 2011, English, 日本循環器学会, 横浜, Domestic conferenceLeft Ventricular Longitudinal Dyssynchrony in Patients with Severe Aortic Valve StenosisOral presentation
- 第75回日本循環器学会総会・学術集会, Mar. 2011, English, 日本循環器学会, 横浜, Domestic conferenceImpact of Left Ventricular Dyssynchrony on Cardiac Sympathetic Activity in Heart Failure Patients with Wide QRS DurationOral presentation
- American Heart Association 2010, Nov. 2010, English, American Heart Association, シカゴ, アメリカ合衆国, International conferenceUtility of Comprehensive Assessment of Strain Dyssynchrony Index by Speckle Tracking Imaging for Predicting Response to Cardiac Resynchronization TherapyPoster presentation
- American Heart Association 2010, Nov. 2010, English, American Heart Association, シカゴ, アメリカ合衆国, International conferenceRegional Myocardial Systolic Function Using Transmural Myocardial Strain Profile Predicts Postoperative Left Ventricular Systolic Dysfunction in Chronic Aortic RegurgitationPoster presentation
- American Heart Association 2010, Nov. 2010, English, American Heart Association, シカゴ, アメリカ合衆国, International conferenceArea Strain Dyssynchrony Index by Three-dimensional Speckle Tracking Imaging Predicts Left Ventricular Reverse Remodeling with Cardiac Resynchronization TherapyPoster presentation
- 日本超音波医学会 第37回関西地方会学術集会, Oct. 2010, Japanese, 日本超音波医学会, 神戸, Domestic conference卵円孔に血栓が陥入した急性肺血栓塞栓症の一例Oral presentation
- 日本超音波医学会 第37回関西地方会学術集会, Oct. 2010, Japanese, 日本超音波医学会, 神戸, Domestic conference心エコー図検査が治療方針決定に有用であった左室流出路狭窄の2症例Oral presentation
- 日本超音波医学会 第37回関西地方会学術集会, Oct. 2010, Japanese, 日本超音波医学会, 神戸, Domestic conference重症三尖弁閉鎖不全に対して三尖弁形成術を行い、良好な結果を得た高齢Ebstein奇形の一例Oral presentation
- 第14回日本心不全学会学術集会, Oct. 2010, Japanese, 日本心不全学会, 東京, Domestic conferenceLöffler’s endocarditis with severely impaired left ventricular function and thrombusPoster presentation
- 第58回日本心臓病学会学術集会, Sep. 2010, Japanese, 日本心臓病学会, 東京, Domestic conference重症大動脈弁狭窄症における左室同期不全と左室後負荷の関係Poster presentation
- 日本超音波医学会第83回学術集会, May 2010, Japanese, 日本超音波医学会, 京都, Domestic conference心臓再同期療法の適応決定にストレインは役立つか?Others
- 第21回日本心エコー図学会学術集会, May 2010, Japanese, 日本心エコー図学会, 北海道, Domestic conference重症大動脈弁狭窄症における左室同期不全と左室後負荷の関係Poster presentation
- 第21回日本心エコー図学会学術集会, May 2010, Japanese, 日本心エコー図学会, 札幌, Domestic conference虚血性心疾患におけるハンドグリップ負荷2D speckle tracking心エコー図法の有用性Oral presentation
- 第21回日本心エコー図学会学術集会, May 2010, Japanese, 日本心エコー図学会, 北海道, Domestic conference拡張型心筋症における左室収縮能障害の不均一性と左室同期不全との関係 -Real-time 3D 心エコー図法を用いた検討-Poster presentation
- 日本超音波医学会第83回学術集会, May 2010, Japanese, 日本超音波医学会, 京都, Domestic conferenceEffectiveness of pimobendan for intractable heart failure caused by cardiac sarcoidosis. A case report.Oral presentation
- The American Society of Echocardiography 19th Annual Scientific Sessions, Jun. 2008, English, American Society of Echocardiography, トロント, カナダ, International conferenceScreening Utility of Electrocardiography and Echocardiography for Progressive Hypertrophic CardiomyopathyPoster presentation
- The World Congress of Cardiology 2008, May 2008, English, World Congress of Cardiology, ブエノスアイレス, アルゼンチン, International conferenceThe Role of Abnormal Q Waves and ST-Segment Elevation as a Marker for Disease Progression in Hypertrophic CardiomyopathyPoster presentation
- 第55回日本心臓病学会学術集会, Sep. 2007, Japanese, 日本心臓病学会, 東京, Domestic conference無症候性慢性大動脈弁閉鎖不全症患者における、収縮期ストレインレートの予後指標としての重要性Oral presentation
- 第80回日本超音波医学会学術集会, May 2007, Japanese, 日本超音波医学会, 鹿児島, Domestic conference急速に進行した感染性心内膜炎の一例Poster presentation
- 第182回日本内科学会近畿地方会, May 2007, Japanese, 日本内科学会, 大阪, Domestic conference化学療法が著効した心臓原発悪性リンパ腫の1例Oral presentation
- 日本心エコー図学会学術集会, Apr. 2007, Japanese, 日本心エコー図学会, 長野県軽井沢, Domestic conference肥大型心筋症における左房機能の評価 -等尺性ハンドグリップ運動負荷を併用した左房strain rateによる検討-Oral presentation
- 日本心エコー図学会学術集会, Apr. 2007, Japanese, 日本心エコー図学会, 長野県軽井沢, Domestic conference左室内血栓を伴った左室緻密化障害の一例Oral presentation