Research activity information

• Uterine rupture in intramural ectopic pregnancy: A case report.

  Keiichi Washio, Masato Komatsu, Masako Tomimoto, Akiko Uchida, Yuki Sasagawa, Masashi Nishimoto, Satoshi Nagamata, Yui Yamasaki, Kenji Tanimura, Yoshito Terai

  Intramural pregnancy is a rare form of ectopic pregnancy. It is defined by a gestation within the uterine wall, completely surrounded by myometrium and separated from the uterine cavity and the fallopian tube. We report a rare case of intramural ectopic pregnancy. If a patient has a history of intrauterine surgery or myomectomy, the possibility of intramural pregnancy, although rare, should not be ruled out.

  Jan. 2023, Asian journal of endoscopic surgery, English, Domestic magazine


• Postsurgical urodynamic study of total laparoscopic nerve-sparing radical hysterectomy for uterine cervical cancer.

  Shinichi Terada, Yoshito Terai, Yoshimichi Tanaka, Tomohito Tanaka, Satoshi Tsunetoh, Masahide Ohmichi

  AIM: To evaluate the impact on urodynamic results between the laparoscopic nerve-sparing radical hysterectomy (LRH) following a step-by-step procedure and abdominal nerve-sparing radical hysterectomy (ARH) for patients with uterine cervical cancer. METHODS: This retrospective study enrolled 76 patients with cervical cancer: 35 in the LRH group and 41 in the ARH group. We analyzed their postoperative bladder function in a urodynamics study and examined the volume of resected pelvic nerves contained in parametrial sections using S-100 antibody staining. RESULTS: Estimated blood loss and hospital stay after operation for the LRH group were significantly better than those in the ARH group (p < 0.0001). As well, the number of harvested lymph nodes was significantly higher in the LRH group (p = 0.044). There was no difference in perioperative complications between the two groups in this study. The 5-year disease-free survival rates and overall survival rates were 91.2% and 94.0% in the LRH group and 87.8% and 95.1% in the ARH group, both respectively. Although the median residual urine volume were no statistical differences between the LRH group and the ARH group, the recovery of postoperative bladder function (uroflowmetry) in the LRH group rapidly reached presurgery levels at 1 month, and the LRH group had a smaller number of s-100 antibody stained nerves contained the parametrial sections. CONCLUSION: We demonstrated that LRH following a step-by-step procedure could achieve a higher level of prevention of damage to the bladder branch of the pelvic splanchnic nerve plexus and thus restore bladder function more rapidly.

  Nov. 2022, The journal of obstetrics and gynaecology research, 48(11) (11), 2863 - 2871, English, International magazine

  Scientific journal


• 梅毒の診療 ベンザチンペニシリンG筋肉注射治療も含め

  今福 仁美, 出口 雅士, 大路 剛, 寺井 義人

  「産婦人科の進歩」編集室, Aug. 2022, 産婦人科の進歩, 74(3) (3), 466 - 468, Japanese


• 妊娠中の副甲状腺摘出により正期産児を得た原発性副甲状腺機能亢進症合併妊娠の一例

  久保田 いろは, 今福 仁美, 益子 尚久, 福岡 秀規, 手島 直則, 谷村 憲司, 出口 雅士, 寺井 義人

  日本女性栄養・代謝学会, May 2022, 日本女性栄養・代謝学会誌, 27(2) (2), 131 - 131, Japanese


• Oncologic outcomes in elderly patients who underwent hysterectomy for endometrial cancer: a multi-institutional survey in Kinki District, Japan

  Tomohito Tanaka, Suguru Yamashita, Haruo Kuroboshi, Junya Kamibayashi, Atsushi Sugiura, Kaori Yoriki, Taisuke Mori, Kazuharu Tanaka, Aiko Nagashima, Michihide Maeda, Shoji Kamiura, Yukako Mizuno, Noriko Ohtake, Tomoyuki Ichimura, Taiki Kikuchi, Yuri Nobuta, Tsukuru Amano, Noriomi Matsumura, Hidekatsu Nakai, Eiji Kobayashi, Yuji Kamei, Masayo Ukita, Junzo Hamanishi, Junya Hirayama, Yasushi Mabuchi, Seiko Kato, Hiroyuki Fujita, Atsuko Kiyota, Shinsuke Koyama, Yosuke Fukui, Mai Kimura, Ryosuke Takahashi, Yoshito Terai, Madoka Suruga, Masaru Kawanishi, Kazuhiro Nishioka, Masahide Ohmichi

  Springer Science and Business Media LLC, Mar. 2022, International Journal of Clinical Oncology

  [Refereed]

  Scientific journal


• PET/MRI is useful for early detection of pelvic insufficiency fractures after radiotherapy for cervical cancer.

  Maho Azumi, Masuyo Matsumoto, Kaho Suzuki, Ryohei Sasaki, Yoshiko Ueno, Munenobu Nogami, Yoshito Terai

  Radiotherapy (RT) is used to manage cervical cancer, and pelvic insufficiency fracture (PIF) is known as a late complication of RT. The present study identified risk factors for PIF after radiotherapy for cervical cancer, and investigated its incidence rate. It also considered the usefulness of positron emission tomography/magnetic resonance imaging (PET/MRI) in PIF diagnosis. A total of 149 patients with cervical cancer who received definitive or adjuvant RT with/without concurrent chemotherapy between January 2013 and December 2018 were investigated in the present study and followed up for more than one month after RT at Kobe University Hospital. The median follow-up period was 32 months (range, 1-87 months), and the median age of all patients was 66 years (age range, 34-90 years). Computed tomography (CT), MRI, PET/CT or PET/MRI were used for image examination. Among the 149 patients, 31 (20.8%) developed PIF. The median age of these patients was 69 years (age range, 44-87 years). Univariate analysis using the log-rank test demonstrated that age (≥60 years) was significantly associated with PIF. The median maximum standardized uptake value of PIF sites on PET/CT was 4.32 (range, 3.04-4.81), and that on PET/MRI was 3.97 (range, 1.21-5.96) (P=0.162). Notably, the detection time of PIF by PET/MRI was significantly earlier compared with PET/CT (P<0.05). The incidence of PIF after RT for cervical cancer was 20.8%, and age was significantly associated with risk factors for such fractures. Taken together, these results suggest that PET/MRI, which offers the advantage of decreased radiation exposure to the patient, is useful for diagnosing PIF and can detect it earlier than PET/CT imaging.

  Nov. 2021, Oncology letters, 22(5) (5), 776 - 776, English, International magazine

  Scientific journal


• Sudden fetal death with placental mesenchymal dysplasia complicated by placenta previa.

  Kenji Tanimura, Yutoku Shi, Hitomi Imafuku, Takaaki Nakanishi, Maki Kanzawa, Yoshito Terai

  Placental mesenchymal dysplasia (PMD) is a rare placental abnormality that is closely related to severe pregnancy complications. A 27-year-old woman with fetal growth restriction and placenta previa was referred to a university hospital at 22 gestational weeks (GW). She was suspected of having a twin pregnancy with a complete or partial hydatidiform mole and coexisting normal live fetus, because two separate placentas, an enlarged one with multiple cystic lesions and a normal one, were shown on ultrasound examinations. At 27 GW, she experienced a sudden intrauterine fetal death (IUFD) after bleeding due to placenta previa, despite confirmation of fetal well-being at 2 h before bleeding. After delivery, histopathological examination confirmed the diagnosis of PMD. This is the first documented case of a woman with PMD and placenta previa who had a sudden IUFD after bleeding. Patients with both PMD and placenta previa should be considered at extremely high risk for IUFD.

  Nov. 2021, The journal of obstetrics and gynaecology research, 47(11) (11), 4087 - 4092, English, International magazine

  [Refereed]


• Abdominal compartment syndrome in a monochorionic-triamniotic triplet pregnancy complicated by feto-fetal transfusion syndrome.

  Kenta Obata, Kenji Tanimura, Naohisa Masuko, Hitomi Imafuku, Moritoki Egi, Yoshito Terai

  A 40-year-old primigravida woman with a monochorionic-triamniotic (MT) triplet pregnancy was hospitalized due to threatened abortion at 16 gestational weeks. Polyhydramnios in two fetuses and oligohydramnios in the third supported a diagnosis of feto-fetal transfusion syndrome (FFTS) at 23 weeks and 3 days of gestation. Severe dyspnea and liver dysfunction required intensive care unit admission and mechanical ventilation support, and abdominal compartment syndrome (ACS) caused by polyhydramnios was clinically diagnosed. When her general condition was not improved regardless of intensive care, the patient delivered the three fetuses by cesarean section at 23 weeks and 5 days gestation. Abdominal decompression was achieved with delivery, and the patient was discharged 13 days after operation without morbidity. This is the first case report of ACS caused by FFTS in a MT triplet pregnancy resulting in extremely preterm birth.

  Sep. 2021, The journal of obstetrics and gynaecology research, 47(9) (9), 3370 - 3373, English, International magazine

  [Refereed]


• Clinical factors associated with a placenta accreta spectrum.

  Hitomi Imafuku, Kenji Tanimura, Yutoku Shi, Akiko Uchida, Masashi Deguchi, Yoshito Terai

  INTRODUCTION: Placenta accreta spectrum (PAS) is a life-threating obstetric complication, and prenatal prediction of PAS can decrease maternal morbidity and mortality. The aim of this prospective cohort study was to determine the clinical factors associated with PAS. METHODS: Pregnant women who delivered at a university hospital were enrolled. Clinical data were collected from medical records, and logistic regression analyses were performed to determine which clinical factors were associated with PAS. RESULTS: Eighty-seven (2.1%) of the 4146 pregnant women experienced PAS. Multivariable analyses revealed that a prior history of cesarean section (CS) (OR 3.3; 95% CI 1.9-5.7; p < 0.01), dilation and curettage (D&C) (OR 2.8; 95% CI 1.7-4.6; p < 0.01), hysteroscopic surgery (OR 5.7; 95% CI 2.3-14.4; p < 0.01), uterine artery embolization (UAE) (OR 44.1; 95% CI 13.8-141.0; p < 0.01), current pregnancy via assisted reproductive technology (ART) (OR 4.1; 95% CI 2.4-7.1; p < 0.01), and the presence of placenta previa in the current pregnancy (OR 13.1; 95% CI 7.9-21.8; p < 0.01) were independently associated with the occurrence of PAS. CONCLUSION: Pregnant women who have a prior history of CS, D&C, hysteroscopic surgery, UAE, current pregnancy via ART, and the presence of placenta previa in the current pregnancy are high risk for PAS.

  Sep. 2021, Placenta, 112, 180 - 184, English, International magazine

  Scientific journal


• 非初感染母体から出生した重篤な症候性先天性サイトメガロウイルス感染症児の一例

  今福 仁美, 谷村 憲司, 益子 尚久, 内田 明子, 藤本 将史, 京野 由紀, 藤岡 一路, 出口 雅士, 寺井 義人

  (一社)日本周産期・新生児医学会, Jun. 2021, 日本周産期・新生児医学会雑誌, 57(Suppl.) (Suppl.), P163 - P163, Japanese


• 胎児治療と新生児治療の併用は先天性サイトメガロウイルス感染症児の予後を改善する

  谷村 憲司, 施 裕徳, 内田 明子, 今福 仁美, 藤岡 一路, 森岡 一朗, 出口 雅士, 峰松 俊夫, 寺井 義人, 山田 秀人

  (一社)日本周産期・新生児医学会, Jun. 2021, 日本周産期・新生児医学会雑誌, 57(Suppl.) (Suppl.), P177 - P177, Japanese


• Survey of the clinical practice pattern of using sentinel lymph node biopsy in patients with gynecological cancers in Japan: the Japan Society of Gynecologic Oncology study.

  Shinichi Togami, Hiroaki Kobayashi, Hitoshi Niikura, Muneaki Shimada, Nobuyuki Susumu, Tomohito Tanaka, Yoshito Terai, Tomoyuki Nagai, Tsukasa Baba, Hideaki Yahata, Wataru Yamagami, Ken Yamaguchi, Tsuyoshi Yamashita, Nobuo Yaegashi, Hidetaka Katabuchi, Daisuke Aoki

  BACKGROUND: Sentinel lymph node (SN) biopsy is essential for evaluating survival and minimal treatment-related morbidity associated with cervical, endometrial, and vulvar cancer in Japan. As such, our aim in this study was to evaluate the current practice pattern of using SN biopsy for cervical, endometrial, and vulvar cancer in Japan. METHODS: We deployed a 47-question survey on the use of SN biopsy for gynecological cancers to 216 gynecological oncology training facilities. The survey included information on the use of SN biopsy for uterine (cervical and endometrial) and vulvar cancers; details on the type, timing, and concentration of tracers used; surgical approach used for SN biopsy; method of biopsy and pathological examination; and facilities' experience with clinical research on SN biopsy. RESULTS: The response rate was 84% (181/216), with 40 facilities (22%) having experience in SN biopsy for gynecological cancers, 34 (85%) for uterine cancers, and 15 (37%) for vulvar cancers. Radioisotope, indocyanine green (ICG), and blue dyes were available for the detection of uterine cancers in 21 (52%), 25 (62%), and 19 (48%) facilities and for vulvar cancers in 9 (22%), 3 (7%), and 11 (27%) facilities, respectively. Thirty-four facilities (85%) used intraoperative frozen section procedure for diagnosis when possible, with 24 (71%) of these facilities using 2-mm specimen cuts. Diagnosis included pathological examination (85%), immunostaining (57%), and one-step nucleic acid amplification (5%). CONCLUSION: Increasing research evidence, providing insurance coverage for radioisotope tracers, and increasing the availability of training are expected to increase the use of SN biopsy in Japan.

  May 2021, International journal of clinical oncology, 26(5) (5), 971 - 979, English, Domestic magazine

  [Refereed]

  Scientific journal


• 胎児間輸血症候群によりabdominal compartment syndromeを発症した1症例

  益子 尚久, 谷村 憲司, 小畑 権大, 今福 仁美, 出口 雅士, 寺井 義人

  「産婦人科の進歩」編集室, May 2021, 産婦人科の進歩, 73(2) (2), 137 - 137, Japanese


• 症候性先天性サイトメガロウイルス感染症に対する胎児治療と新生児治療の有効性の検討

  谷村 憲司, 施 裕徳, 内田 明子, 上中 美月, 今福 仁美, 藤岡 一路, 森岡 一朗, 出口 雅士, 寺井 義人, 山田 秀人

  「産婦人科の進歩」編集室, May 2021, 産婦人科の進歩, 73(2) (2), 152 - 152, Japanese


• 先進医療下子宮体癌に対する腹腔鏡下傍大動脈リンパ節郭清術登録結果の検討

  鈴木 嘉穂, 高橋 良輔, 山中 啓太郎, 鷲尾 佳一, 清水 真帆, 長又 哲史, 村田 友香, 出口 雅士, 寺井 義人

  (公社)日本婦人科腫瘍学会, Jan. 2021, 日本婦人科腫瘍学会雑誌, 39(1) (1), 115 - 115, Japanese


• 腹腔鏡下手術及び開腹手術との比較によるロボット支援下準広汎子宮全摘術導入の安全性に関する検討

  村田 友香, 鈴木 嘉穂, 山中 啓太郎, 安積 麻帆, 鷲尾 佳一, 清水 真帆, 高橋 良輔, 長又 哲史, 松本 培世, 出口 雅士, 寺井 義人

  (公社)日本婦人科腫瘍学会, Jan. 2021, 日本婦人科腫瘍学会雑誌, 39(1) (1), 294 - 294, Japanese


• Saturated salt solution固定法Cadaverを用いた腹腔鏡下婦人科悪性腫瘍手術トレーニング

  長又 哲史, 山中 啓太郎, 安積 麻帆, 清水 真帆, 鷲尾 佳一, 高橋 良輔, 村田 友香, 鈴木 嘉穂, 出口 雅士, 寺井 義人

  (公社)日本婦人科腫瘍学会, Jan. 2021, 日本婦人科腫瘍学会雑誌, 39(1) (1), 311 - 311, Japanese


• 後期高齢者における抗がん剤治療の安全性についての検討

  高橋 良輔, 山中 啓太郎, 安積 麻帆, 鷲尾 佳一, 清水 真帆, 長又 哲史, 村田 友香, 鈴木 嘉穂, 出口 雅士, 寺井 義人

  (公社)日本婦人科腫瘍学会, Jan. 2021, 日本婦人科腫瘍学会雑誌, 39(1) (1), 318 - 318, Japanese


• The therapeutic potential of exosomal miR-22 for cervical cancer radiotherapy.

  Hiromi Konishi, Masami Hayashi, Kohei Taniguchi, Mayumi Nakamura, Yuki Kuranaga, Yuko Ito, Yoichi Kondo, Hiroshi Sasaki, Yoshito Terai, Yukihiro Akao, Masahide Ohmichi

  Cervical cancer is the fourth-most prevalent malignancy in women. For advanced cervical cancer, radiotherapy is a major treatment. Micro RNAs (miRNAs) are small, noncoding RNAs that negatively regulate the target gene expression posttranscriptionally. miR-22 is frequently downregulated in various cancers including cervical cancer, and is associated with a poor prognosis in cervical cancer. Exosomes are small endosomally secreted vesicles that carry components such as proteins, messenger RNA (mRNA), DNA and miRNA. We investigated whether or not exosomes can efficiently deliver miR-22 to recipient cervical cancer cells and affect the gene expression in the cells, as well as assessed the role of exosomal miR-22 in radiosensitivity. Exosomes containing high levels of miR-22 were extracted by ultracentrifugation and then characterized by Western blotting, a nanoparticle tracking analysis and electron microscopy. The high presence of miR-22 in the exosome was confirmed by real-time polymerase chain reaction. After the administration of the collected exosomal miR-22 to SKG-II and C4-I cervical cancer cells, the level of miR-22 in the cells was significantly increased, indicating the absorption of the exosomal miR-22. When miR-22 encapsulated in exosomes was administered to the SKG-II cells, the level of c-Myc binding protein (MYCBP) and human telomerase reverse transcriptase (hTERT) was significantly decreased in correlation with increased radiosensitivity determined by a clonogenic assay. Taken together, these results suggest that the administration of exosomal miR-22 may be a novel drug delivery system for cervical cancer radiotherapy.

  Dec. 2020, Cancer biology & therapy, 21(12) (12), 1128 - 1135, English, International magazine

  [Refereed]

  Scientific journal


• 卵巣癌・原発性腹膜癌の術前化学療法時の診断において、腹腔鏡下生検と体腔液cell block法の比較検討

  高橋 良輔, 清水 真帆, 長又 哲史, 松本 培世, 村田 友香, 鈴木 嘉穂, 出口 雅士, 寺井 義人

  「産婦人科の進歩」編集室, Aug. 2020, 産婦人科の進歩, 72(3) (3), 211 - 215, Japanese


• The differential expression of miRNAs between ovarian endometrioma and endometriosis-associated ovarian cancer.

  Natsuho Nakamura, Yoshito Terai, Misa Nunode, Kana Kokunai, Hiromi Konishi, Sayaka Taga, Mayumi Nakamura, Masae Yoo, Masami Hayashi, Yoshiki Yamashita, Masahide Ohmichi

  BACKGROUND: MicroRNAs (miRNAs) have been implicated to play a vital role in development, differentiation, cell proliferation and apoptosis. However, which miRNAs are actually associated with endometriosis-associated ovarian cancer remains controversial. METHODS: Serum and ascites samples were obtained from all patients. Serum samples from 5 cases of ovarian endometrioma and endometriosis-associated ovarian cancer each were submitted for comprehensive miRNA microarray profiling. We investigated the differential expression of miRNAs between the two groups to confirm the pivotal role of miRNAs. Quantitative reverse transcription-polymerase chain reaction validation of five selected miRNAs [miR-92a-3p, miR-486-5p, miR-4484, miR-6821-5p, and miR-7108-5p] was performed, and miR-486-5p expression analysis was followed by proliferation and wound healing assays, depending on the expression of miR-486-5p. RESULT: miR-486-5p expression in serum and ascites samples from endometriosis-associated ovarian cancer patients was significantly higher than that from ovarian endometrioma patients. Moreover, the miR-486-5p level in serum and ascites samples was significantly correlated with the severity of the endometriosis. The upregulation of miR-486-5p in immortalized ovarian endometrioma cells significantly increased proliferation and migration. In contrast, the downregulation of miR-486-5p in these cells significantly decreased proliferation and migration. CONCLUSION: miR-486-5p might function as an oncogenic miRNA in endometriosis-associated ovarian cancer and could be a noninvasive biomarker to prospect the severity of ovarian endometrioma.

  May 2020, Journal of ovarian research, 13(1) (1), 51 - 51, English, International magazine

  Scientific journal


• Sex cord tumor with annular tubulesの1例

  峯 凪り, 寺井 義人, 山中 啓太郎, 鷲尾 佳一, 清水 真帆, 高橋 良輔, 長又 哲史, 村田 友香, 鈴木 嘉穂, 出口 雅士, 山田 秀人

  「産婦人科の進歩」編集室, May 2020, 産婦人科の進歩, 72(2) (2), 169 - 169, Japanese


• 子宮筋腫の術前治療におけるGnRHアンタゴニストの有用性についての検討

  山中 啓太郎, 寺井 義人, 高橋 良輔, 鷲尾 佳一, 清水 真帆, 松本 培世, 長又 哲史, 村田 友香, 鈴木 嘉穂, 出口 雅士, 山田 秀人

  「産婦人科の進歩」編集室, May 2020, 産婦人科の進歩, 72(2) (2), 186 - 186, Japanese


• イリノテカン+シスプラチン療法が奏功した局所進行子宮頸部小細胞癌の一例

  安積 麻帆, 鈴木 嘉穂, 出口 雅士, 松本 培世, 長又 哲史, 高橋 良輔, 蝦名 康彦, 寺井 義人

  (公社)日本婦人科腫瘍学会, Apr. 2020, 日本婦人科腫瘍学会雑誌, 38(2) (2), 193 - 199, Japanese


• Pharmacokinetic evaluation and antitumor potency of liposomal nanoparticle encapsulated cisplatin targeted to CD24-positive cells in ovarian cancer.

  Keisuke Ashihara, Yoshito Terai, Tomohito Tanaka, Yoshimichi Tanaka, Satoe Fujiwara, Kazuya Maeda, Satoshi Tunetoh, Hiroshi Sasaki, Masami Hayashi, Masahide Ohmichi

  CD24, which is upregulated in several human malignancies, is related to Epithelial-mesenchymal-transition (EMT) and has characteristics of cancer stem-like cells, especially in cisplatin-resistant ovarian carcinoma cells. Drug delivery systems represent a promising therapeutic approach for diseases with treatment resistance, and the present study investigated a novel CD24-targeted drug delivery system for advanced ovarian carcinoma. We produced liposomal cisplatin with a red fluorescent substance - cyanine 5.5 (GL-CDDP-Cy5.5). In order to target CD24-positive cells, an anti-CD24 monoclonal antibody was modified to the above drug (CD24-GL-CDDP-Cy5.5). Specific uptake of CD24-GL-CDDP-Cy5.5 was confirmed using a therapeutically resistant ovarian cancer cell line, Caov-3 cells. Antitumor effects of CD24-GL-CDDP-Cy5.5 were then evaluated in Caov-3 ×enograft mice. CD24-GL-CDDP-Cy5.5 showed more specific uptake by flow cytometry than GL-CDDP-Cy5.5. In xenograft mice, GL-CDDP-Cy5.5 and CD24-GL-CDDP-Cy5.5 treatment had significantly higher platinum concentration in disseminated tumor cells than cisplatin (P<0.05). Moreover, CD24-GL-CDDP-Cy5.5 suppressed tumor growth and prolonged survival time compared with other treatments. Median survival times of the control, cisplatin, GL-CDDP-Cy5.5 and CD24-GL-CDDP-Cy5.5 groups were 37, 36, 46 and 54 days after inoculation, respectively. Immunohistochemical analysis showed that CD24-GL-CDDP-Cy5.5 treatment, compared with GL-CDDP-Cy5.5, decreased the number of CD24-positive cells and suppressed the EMT phenomenon significantly (P<0.05). The present study demonstrated that CD24-GL-CDDP-Cy5.5, compared with other treatments, improved therapeutic efficacy. The present results suggested the potential for targeting anticancer therapeutics for CD24-positive cells to prevent disease progression.

  Mar. 2020, Oncology letters, 19(3) (3), 1872 - 1880, English, International magazine

  Scientific journal


• 卵巣癌において浸潤能,遊走能を促進する新規遺伝子の検索

  川口 徹也, 清水 真帆, 鷲尾 佳一, 高橋 良輔, 長又 哲史, 松本 培世, 村田 友香, 鈴木 嘉穂, 出口 雅士, 山田 秀人, 寺井 義人, 鈴木 聡

  (公社)日本産科婦人科学会, Mar. 2020, 日本産科婦人科学会雑誌, 72(臨増) (臨増), S - 401, Japanese


• 当院における子宮頸癌に対するベバシズマブの使用経験

  長又 哲史, 山中 啓太郎, 鷲尾 佳一, 清水 真帆, 高橋 良輔, 松本 培世, 鈴木 嘉穂, 出口 雅士, 寺井 義人, 山田 秀人

  (公社)日本産科婦人科学会, Mar. 2020, 日本産科婦人科学会雑誌, 72(臨増) (臨増), S - 490, Japanese


• 子宮頸癌に対する放射線治療後の不全骨折発症のリスク因子についての後方視的検討

  松本 培世, 鈴木 嘉穂, 鷲尾 佳一, 清水 真帆, 高橋 良輔, 長又 哲史, 村田 友香, 出口 雅士, 山田 秀人, 寺井 義人

  (公社)日本産科婦人科学会, Mar. 2020, 日本産科婦人科学会雑誌, 72(臨増) (臨増), S - 535, Japanese


• 当院におけるロボット支援下手術の導入と腹腔鏡手術との比較検討

  鈴木 嘉穂, 長又 哲史, 山中 啓太郎, 鷲尾 佳一, 清水 真帆, 高橋 良輔, 松本 培世, 村田 友香, 出口 雅士, 山田 秀人, 寺井 義人

  (公社)日本産科婦人科学会, Mar. 2020, 日本産科婦人科学会雑誌, 72(臨増) (臨増), S - 627, Japanese


• BevacizumabとOlaparibの併用療法によって再発卵巣癌治療は変わったか?

  高橋 良輔, 鈴木 嘉穂, 山中 啓太郎, 鷲尾 佳一, 清水 真帆, 長又 哲史, 松本 培世, 村田 友香, 出口 雅士, 山田 秀人, 寺井 義人

  (公社)日本産科婦人科学会, Mar. 2020, 日本産科婦人科学会雑誌, 72(臨増) (臨増), S - 643, Japanese


• MicroRNA-22 enhances radiosensitivity in cervical cancer cell lines via direct inhibition of c-Myc binding protein, and the subsequent reduction in hTERT expression.

  Mayumi Nakamura, Masami Hayashi, Hiromi Konishi, Misa Nunode, Keisuke Ashihara, Hiroshi Sasaki, Yoshito Terai, Masahide Ohmichi

  MicroRNAs (miRs) influence the expression of their target genes post-transcriptionally and serve an important role in multiple cellular processes. The downregulation of miR-22 is associated with a poor prognosis in cervical cancer. However, the mechanisms underlying miR-22-mediated gene regulation and its function are yet to be elucidated. In the present study, the effect of miR-22 expression on the radiosensitivity of cervical cancer was investigated. First, miR-22 was either up- or downregulated to evaluate the regulation of the MYC-binding protein (MYCBP) in four cervical cancer cell lines (C-4I, SKG-II and SiHa). Notably, MYCBP expression was inversely associated with miR-22 induction. A dual-luciferase reporter gene assay revealed that miR-22 directly targets the MYCBP 3'-untranslated region. Subsequently, the level of human telomerase reverse transcriptase component (hTERT; an E-box-containing c-Myc target gene) was analyzed after the up- or downregulation of miR-22. Notably, miR-22-mediated repression of MYCBP reduced hTERT expression. In addition, the influence of miR-22 on radiosensitivity in C-4I, SKG-II and SiHa cells was examined using a clonogenic assay and in mouse xenograft models. Upregulation of miR-22 was associated with increased radiosensitivity. Furthermore, lentiviral transduction of miR-22 reduced the Ki-67 index while increasing the TUNEL index in xenograft tissue. The current findings indicate the potential utility of miR-22 in radiotherapy for cervical cancer.

  Mar. 2020, Oncology letters, 19(3) (3), 2213 - 2222, English, International magazine

  Scientific journal


• A Case of Significant Response to Olaparib in a Patient with Primary Peritoneal Carcinosarcoma Diagnosed by Laparoscopic Surgery.

  Satoshi Nagamata, Yukiko Nakasuji, Keitaro Yamanaka, Maho Azumi, Keiichi Washio, Maho Shimizu, Ryosuke Takahashi, Kazuyo Matsumoto, Yuka Murata, Kaho Suzuki, Masashi Deguchi, Hideto Yamada, Yoshito Terai

  Primary peritoneal carcinosarcomas which arise from extragenital locations are extremely rare. Carinosarcomas contain both carcinomatous and sarcomatous elements and can be mainly detected in the female genital tract. We herein report a case of primary peritoneal carcinosarcoma diagnosed by laparoscopic surgery and treated with olaparib. A 62-year-old woman referred to our hospital due to abdominal distension. From imaging findings, we suspected advanced primary peritoneal carcinoma, and laparoscopic surgery was thereafter performed. The pathological diagnosis was carcinosarcoma, and the patient received chemotherapy with docetaxel and carboplatin. After three cycles of chemotherapy, the interval debulking surgery was attempted but resulted in suboptimal results. Because the bilateral ovaries were observed with a normal size and normal findings, we considered that the most likely diagnosis was primary peritoneal carcinosarcoma. After the additional chemotherapy and a 6-month observation period, the tumor relapsed. The patient received chemotherapy again, and the peritoneal carcinosarcoma was judged to be a platinum-sensitive tumor. Oral administration of olaparib was thus initiated. Although a dose reduction was needed due to anemia, olaparib was effective, and the patient could continue the drug for another 7 months. This is the first report of primary peritoneal carcinosarcoma treated with olaparib and shows that it could be a treatment option for platinum-sensitive tumors.

  2020, Case reports in obstetrics and gynecology, 2020, 9106390 - 9106390, English, International magazine


• 当院における子宮頸癌に対するベバシズマブの使用経験

  長又 哲史, 清水 真帆, 高橋 良輔, 松本 培世, 村田 友香, 鈴木 嘉穂, 出口 雅士, 寺井 義人

  「産婦人科の進歩」編集室, Oct. 2019, 産婦人科の進歩, 71(4) (4), 419 - 419, Japanese


• 当科における腹腔鏡下子宮悪性腫瘍手術の導入と治療成績

  長又 哲史, 安積 麻帆, 清水 真帆, 高橋 良輔, 松本 培世, 鈴木 嘉穂, 出口 雅士, 寺井 義人

  (一社)日本産科婦人科内視鏡学会, Aug. 2019, 日本産科婦人科内視鏡学会雑誌, 35(Suppl.I) (Suppl.I), 281 - 281, Japanese


• Urodynamic outcomes after pelvic nerve-sparing radical hysterectomy with or without neoadjuvant chemotherapy.

  Tsunetoh S, Terai Y, Takai M, Fujiwara S, Tanaka Y, Tanaka T, Sasaki H, Ibuki N, Ubai T, Yamamoto K, Azuma H, Ohmichi M

  OBJECTIVE: Our purposes of this study were to characterize a group of bulky cervical cancer patients who underwent a nerve sparing radical hysterectomy (NSRH) with or without neoadjuvant chemotherapy (NAC), to compare surgical outcomes and the preservation of bladder function, and to compare prognoses. RESULTS: Fifty-three patients had NSRH without NAC (Group A), and 33 patients had NSRH after NAC (Group B). With regard to prognostic factors, there was only a significant difference between both groups with regard to lymph node metastasis (15% vs 42%, P = 0.01). Moreover, bladder function in Group B patients improved to the same extent as the preoperative rate three months postoperatively. These data were similar to the results in Group A. With regard to overall survival, the 5-year survival rate was 98.1% (95% confidence interval (CI) 87.8-99.7) in Group A and 86.7% (95% CI 71.7-96.7) in Group B (P > 0.1). METHODS: We retrospectively identified 86 patients with cervical cancer who underwent NSRH at Osaka Medical College from May 2009 to November 2016. NAC was performed via balloon occluded arterial infusion. We extracted data on the patient's stage of progress, tumor volume, histological subtype, bleeding volume, urodynamic study results, and postoperative complications. The data were divided into two groups - those patients who received NAC and those who did not - and then compared. CONCLUSIONS: According to our analysis, NSRH surgery after NAC via balloon occluded arterial infusion brings beneficial results to patients with bulky IB2 to IIB cervical cancers.

  Aug. 2019, Oncotarget, 10(50) (50), 5207 - 5216, English, International magazine

  [Refereed]

  Scientific journal


• 卵巣癌初回治療におけるdose-dense TC療法とTC+bevacizumab併用療法の比較

  鈴木 嘉穂, 中筋 由紀子, 安積 麻帆, 高橋 良輔, 長又 哲史, 松本 培世, 出口 雅士, 蝦名 康彦, 寺井 義人

  (公社)日本婦人科腫瘍学会, Jun. 2019, 日本婦人科腫瘍学会雑誌, 37(3) (3), 451 - 451, Japanese


• 卵巣癌・腹膜癌の術前化学療法時の診断において、腹腔鏡下生検と体腔液Cell block法の比較検討

  高橋 良輔, 鈴木 嘉穂, 中筋 由紀子, 安積 麻帆, 長又 哲史, 松本 培世, 出口 雅士, 蝦名 康彦, 寺井 義人

  (公社)日本婦人科腫瘍学会, Jun. 2019, 日本婦人科腫瘍学会雑誌, 37(3) (3), 457 - 457, Japanese


• 子宮頸がんに対する放射線治療後不全骨折発症のリスクについての検討

  松本 培世, 鈴木 嘉穂, 安積 麻帆, 中筋 由紀子, 清水 真帆, 高橋 良輔, 長又 哲史, 蝦名 康彦, 出口 雅士, 寺井 義人

  (公社)日本婦人科腫瘍学会, Jun. 2019, 日本婦人科腫瘍学会雑誌, 37(3) (3), 476 - 476, Japanese


• トラベクテジンの長期投与が可能であった平滑筋肉腫の二例

  長又 哲史, 蝦名 康彦, 安積 麻帆, 高橋 良輔, 松本 培世, 鈴木 嘉穂, 出口 雅士, 寺井 義人

  (公社)日本婦人科腫瘍学会, Jun. 2019, 日本婦人科腫瘍学会雑誌, 37(3) (3), 525 - 525, Japanese


• 妊孕性温存手術を施行したI期の卵巣上皮性境界悪性腫瘍の予後に関する検討

  安積 麻帆, 鈴木 嘉穂, 中筋 由紀子, 高橋 良輔, 松本 培世, 長又 哲史, 出口 雅士, 寺井 義人, 山田 秀人

  (公社)日本婦人科腫瘍学会, Jun. 2019, 日本婦人科腫瘍学会雑誌, 37(3) (3), 530 - 530, Japanese


• 卵管留水腫に対する腹腔鏡下卵管切除術前後の卵巣機能と術後妊娠率

  穀内 香奈, 奥田 喜代司, 中村 奈津穂, 田中 理恵, 恒遠 啓示, 林 正美, 寺井 義人, 大道 正英

  「産婦人科の進歩」編集室, May 2019, 産婦人科の進歩, 71(2) (2), 67 - 73, Japanese


• 当院で経験した腹膜原発癌肉腫の2例

  中筋 由紀子, 鈴木 嘉穂, 長又 哲史, 安積 麻帆, 高橋 良輔, 松本 培世, 蝦名 康彦, 出口 雅士, 寺井 義人, 山田 秀人

  「産婦人科の進歩」編集室, May 2019, 産婦人科の進歩, 71(2) (2), 230 - 230, Japanese


• 当院における稀少部位子宮内膜症10例の検討

  古形 祐平, 石川 渚, 飯藤 宰士, 田中 サキ, 中村 奈津穂, 小西 博巳, 恒遠 啓示, 林 正美, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2019, 日本産科婦人科学会雑誌, 71(臨増) (臨増), S - 354, Japanese


• 子宮内膜症関連卵巣癌の病態解明を目的とした遺伝子発現解析

  中村 奈津穂, 宮本 瞬輔, 古形 祐平, 寺田 信一, 小西 博巳, 穀内 香奈, 多賀 紗也香, 林 正美, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2019, 日本産科婦人科学会雑誌, 71(臨増) (臨増), S - 352, Japanese


• 当科におけるがん治療後トータルヘルスケアの取り組み ホルモン補充療法の更年期症状への効果

  佐々木 浩, 石川 渚, 宮本 瞬輔, 中村 奈津穂, 丸岡 寛, 穀内 香奈, 多賀 紗也香, 藤原 聡枝, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2019, 日本産科婦人科学会雑誌, 71(臨増) (臨増), S - 675, Japanese


• Association of matrix metalloproteinase-9 and decorin expression with the infiltration of cervical cancer

  Tanaka T, Terai Y, Ohmichi M

  Matrix metalloproteinase-9 (MMP9) has been recognized to be an important factor in cancer invasion and metastasis. In contrast, decorin has been revealed to inhibit primary tumor development. The aim of the present study was to investigate the function of MMP9 and decorin in cervical cancer. Three experiments were performed to analyze the function of MMP9 and decorin in the invasion of cervical cancer by: i) Analyzing the expression of MMP9 and decorin by immunohistochemistry in 100 cervical specimens; ii) determining the concentration of decorin by an enzyme-linked immunosorbent assay (ELISA) using the human squamous cervical cancer cell line CaSki and human endometrial stromal cell line CRL4003 and iii) evaluating the invasion ability of CaSki cells in a cervical invasion model by an invasion assay. Immunohistochemistry revealed that MMP9 was overexpressed in microinvasive carcinoma (100.0%) but was less strongly expressed in normal or pre-malignant squamous epithelium (0-41.9%). In contrast, the activity of decorin in stroma adjacent to neoplastic cells was lower in microinvasive carcinoma (9.1%) compared with in normal or pre-malignant lesions (74.2-100.0%). An ELISA revealed that MMP9 released from CaSki cells resolved the decorin released from CRL4003 cells. An invasion assay demonstrated that the invasive ability of CaSki cells was suppressed by an MMP inhibitor, and decorin was released from CRL4003 cells. These data suggested that decorin prevented the invasion of malignant cells in uterine cervical cancer; however, MMP9 promotes cell invasion by destroying decorin.

  Jan. 2019, Oncol Lett, 17(1) (1), 1306 - 1312, English, International magazine

  [Refereed]

  Scientific journal


• Rapidly growing juvenile granulosa cell tumor of the ovary arising in adult: a case report and review of the literature

  Inada Y, Nakai G, Yamamoto K, Yamada T, Hirose Y, Terai Y, Ohmichi M, Narumi Y

  Dec. 2018, J Ovarian Res, 11(1) (1), 100, English

  [Refereed]

  Scientific journal


• Neoadjuvant intra-arterial chemotherapy using an original four-lumen double-balloon catheter for locally advanced uterine cervical cancer

  Tanaka T, Terai Y, Fujiwara S, Tanaka Y, Sasaki H, Tsunetoh S, Yamamoto K, Yamada T, Ohmichi M

  OBJECTIVE: We report a balloon-occluded arterial infusion therapy with an original four-lumen double-balloon catheter (4L-DB) which allows for the efficient injection of an anticancer agent at a high concentration to the target spot for patients with locally advanced uterine cervical cancer. METHODS: One hundred and forty-three patients with locally advanced cervical cancer treated with neoadjuvant intra-arterial chemotherapy (NAIAC) or a primary radical hysterectomy (PRH) were retrospectively assessed. The patients in the NAIAC group received irinotecan 70 mg/m2 intravenously on day 1 and 8 and cisplatin 70 mg/m2 intra-arterially using the 4L-DB on day 2 of a 21-day course, and two courses were performed in principle. The radical hysterectomy was performed within 6 weeks after NAIAC. RESULTS: Ninety-four patients were treated with NAIAC, and 49 patients undertook a PRH. The response rate of NAIAC on MRI was 92.6%. Fourteen patients (14.6%) had no evidence of cancer cells on pathologic diagnoses. The NAIAC group had a longer disease-free survival than the PRH group (p=0.02); however, the overall survival was not significantly different. The relative risk (RR) for recurrence was higher in patients with lymph node metastasis (RR, 4.31; 95% CI, 2.23-8.43) and lower in those who underwent NAIAC (RR, 0.30; 95% CI, 0.14-0.68). CONCLUSION: Our results with NAIAC using the 4L-DB catheter in locally advanced cervical cancer indicates beneficial effects on primary lesions and improves disease-free survival.

  Dec. 2018, Oncotarget, 9(102) (102), 37766 - 37776, English, International magazine

  [Refereed]

  Scientific journal


• A case of torsion of a normal ovary in the third trimester of pregnancy: MRI findings with emphasis on asymmetry in the diameter of the ovarian veins

  Tanaka Y, Tsuboyama T, Yamamoto K, Terai Y, Ohmichi M, Narumi Y

  A 33-year-old woman, gravida two para one, at 31 weeks of gestational age experienced sudden onset of left lower quadrant pain and underwent unenhanced pelvic MRI. On fast imaging employing steady state precession (FIESTA) sequence images, a marked difference was observed in the diameters of the right and left ovarian veins. The right ovarian vein was torturous and dilated, measuring 35 mm in diameter, while the left ovarian vein was thin and linear, measuring 7 mm in diameter. The left ovary showed no apparent swelling or hemorrhage, but was suspected to have been shifted anteriorly. The patient underwent explorative laparotomy and was found to have left ovarian torsion. A difference in diameter of the ovarian veins, with thinning of the twisted side and compensatory dilatation of the contralateral side for drainage of increased uterine blood flow, may be a useful imaging sign for the diagnosis of ovarian torsion during pregnancy.

  Dec. 2018, Radiol Case Rep, 14(3) (3), 324 - 327, English, International magazine

  [Refereed]

  Scientific journal


• Establishment of a novel mouse xenograft model of human uterine leiomyoma

  Yusuke Suzuki, Masaaki Ii, Takashi Saito, Yoshito Terai, Yasuhiko Tabata, Masahide Ohmichi, Michio Asahi

  Nature Publishing Group, Dec. 2018, Scientific Reports, 8(1) (1), 8872, English

  [Refereed]

  Scientific journal


• Preoperative diffusion-weighted magnetic resonance imaging and intraoperative frozen sections for predicting the tumor grade in endometrioid endometrial cancer

  Tanaka T, Terai Y, Fujiwara S, Tanaka Y, Sasaki H, Tsunetoh S, Yamamoto K, Yamada T, Narumi Y, Ohmichi M

  Objective: The histological tumor grade is a strong predictor of nodal metastasis in endometrial cancer; as such, an accurate pre- or intraoperative diagnosis is important for performing lymphadenectomy. Methods: Ninety-one patients with endometrioid endometrial cancer were imaged on DW-MRI with the apparent diffusion coefficient (ADC) calculated and a frozen section (FS) diagnosis made before and at hysterectomy. The diagnostic accuracy for predicting the tumor grade for diffusion weighted magnetic resonance inaging (DW-MRI) and the FS diagnosis compared to the ultimate histologic status was analyzed. Results: Among 91 patients with endometrioid endometrial cancer, high-grade (endometrioid G3) tumors had lower ADC values than low-grade (endometrioid G1/2) tumors. The cut-off of the mean ADCmean values for predicting high-grade tumors resulted in 743×10-6 mm2/sec according to the receiver operating characteristic curve. The true positive rates of ADC values and FSs for the prediction of high-grade tumors did not differ to a statistically significant extent (73.3% vs. 66.7%, p=0.7), however, the true negative rate of ADC values for the prediction of low-grade tumors was significantly lower than that of the FSs (64.5% vs. 98.7%, p=0.01). The kappa statistics of ADC values and FSs were 0.23 and 0.73, respectively. Of note, all five patients with high-grade tumors for whom intraoperative FSs indicated low-grade tumors were predicted to have high-grade tumors on preoperative DW-MRI. Conclusion: A FS diagnosis is more suitable for predicting high-grade tumors than DW-MRI; however, physicians should pay close attention to tumors with low ADC values on preoperative DW-MRI.

  Nov. 2018, Oncotarget, 9(93) (93), 36575 - 36584, English, International magazine

  [Refereed]

  Scientific journal


• 内臓脂肪と子宮体癌の臨床病理学的特徴の関係

  丸岡 寛, 佐々木 浩, 大瀧 瑠璃, 田中 サキ, 多賀 紗也香, 古形 祐平, 藤原 聡枝, 田中 智人, 田中 良道, 恒遠 啓示, 寺井 義人, 大道 正英

  (一社)日本女性医学学会, Oct. 2018, 日本女性医学学会雑誌, 26(Suppl.) (Suppl.), 119 - 119, Japanese


• The diagnostic accuracy of fluorodeoxyglucose-positron emission tomography/computed tomography and sentinel node biopsy in the prediction of pelvic lymph node metastasis in patients with endometrial cancer: A retrospective observational study

  TanakaT, YamamotoK, YamadaT, OhmichiM

  According to the sentinel node biopsy (SNB), systematic pelvic lymph node dissection (PLND) may not be needed for patients with early-stage endometrial cancer. On the other hand, imaging technology including fluorodeoxyglucose-positron emission tomography/computed tomography (FDG PET/CT) has been developing worldwide. The aim of this study was to evaluate the combined diagnostic accuracy of FDG PET/CT and SNB in the prediction of pelvic lymph node metastasis in endometrial cancer patients.One hundred twenty-one patients with endometrial cancer underwent FDG PET/CT before hysterectomy and received SNB followed by systematic PLND. Univariate and multivariate analyses were performed to compare the diagnostic accuracy of FDG PET/CT and SNB in the prediction of pelvic node metastasis to the ultimate histologic status.FDG PET/CT had lower sensitivity (36.8% versus 57.9%, P = .1) and a higher specificity (96.4% versus 84.8%, P < .01) than SNB. The kappa statistics of FDG PET/CT and SNB were 0.37 (95% CI, 0.15-0.59) and 0.72 (95% CI, 0.53-0.90), respectively. The sensitivity of SNB was significantly higher than that of FDG PET/CT in all hemi-pelvises (HPs) in which the short axis of the largest metastatic lymph node was <5 mm in diameter (72.7% versus 18.2%, P = .01). In contrast, the sensitivity of FDG PET/CT was higher than that of SNB in all HPs in which the short axis of the largest metastatic lymph node was ≥5 mm in diameter (62.5% versus 37.5%, P = .2); however, the difference was not statistically significant. When the combined diagnosis of FDG PET/CT and SNB was made, the sensitivity and specificity were 84.2% and 82.1%, respectively.SNB was more useful for detecting lymph node metastasis than FDG PET/CT, especially in patients with small metastatic lymph nodes. The combined diagnosis of FDG PET/CT and SNB improves the sensitivity; PET-positive nodes should be dissected regardless of SNB status and HPs in which SNB was not detected should be dissected systematically regardless of FDG PET/CT status.

  Sep. 2018, Medicine (Baltimore), 97(38) (38), e - 12522, English, International magazine

  [Refereed]

  Scientific journal


• 臨床経験 当院における腹式広汎子宮頸部摘出術後の生殖補助医療についての検討

  小西博巳, 古形祐平, 藤原聡枝, 田中良道, 田中智人, 藤田太輔, 林正美, 大道正英

  金原出版(株), Sep. 2018, 産婦人科の実際, 67(9号) (9号), 1047 - 1051, Japanese

  [Refereed]

  Scientific journal


• 子宮内膜症合併不妊症における腹腔鏡下手術についての検討

  小西 博巳, 恒遠 啓示, 寺田 信一, 古形 祐平, 田中 良道, 田中 智人, 佐々木 浩, 林 正美, 寺井 義人, 大道 正英

  (一社)日本産科婦人科内視鏡学会, Aug. 2018, 日本産科婦人科内視鏡学会雑誌, 34(Suppl.I) (Suppl.I), 239 - 239, Japanese


• 腹腔鏡下手術で診断された卵巣原発偽粘液腫の1例

  丸岡 寛, 上田 尚子, 宮本 瞬輔, 小西 博巳, 村山 結美, 多賀 紗也香, 古形 祐平, 藤原 聡枝, 田中 智人, 佐々木 浩, 恒遠 啓示, 寺井 義人, 大道 正英

  (一社)日本産科婦人科内視鏡学会, Aug. 2018, 日本産科婦人科内視鏡学会雑誌, 34(Suppl.I) (Suppl.I), 185 - 185, Japanese


• A case of ovarian clear cell carcinoma arising from ovarian mature cystic teratoma

  MaedaK, TeradaS, MaruokaH, KogataY, AshiharaK, TanakaY, TanakaT, SasakiH, TsunetohS, YamadaT, OhmichiM

  BACKGROUND: It is well known that ovarian mature cystic teratomas (MCTs) occasionally go through malignant transformations. Among these, approximately 75% of histological types are squamous cell carcinoma, with the other types being exceptionally rare. We report an extremely rare case of ovarian clear cell carcinoma arising from ovarian mature cystic teratoma. CASE PRESENTATION: The case was a 71-year-old woman with abdominal distention. Ultrasonography and magnetic resonance imaging showed a huge mass in her abdominal cavity. Fluorodeoxyglucose-positron emission tomography (FDG-PET) showed FDG uptake not only in the pelvic tumor but also in the hepatic nodule, thus suggesting metastases. We performed a total abdominal hysterectomy, bilateral salpingo-oophorectomy, and an omentectomy. The pathological diagnosis showed clear cell carcinoma of the right ovary which arose from the MCT with malignant transformation pT2aNXM1. Although the patient underwent chemotherapy, she died after 17 months. CONCLUSION: This case is histologically characteristic of the proof of transition from simple squamous epithelium via simple glandular epithelium to papillary change with atypia. This is the first case report of unaccompanied clear cell carcinoma arising from MCT reported in English literatures.

  Aug. 2018, J Ovarian Res, 11(1) (1), e - 74, English, International magazine

  [Refereed]

  Scientific journal


• 尿細胞診が発見の契機となった膀胱内に発生した尖圭コンジローマの1例

  橋田宗祐, 藤原聡枝, 大道正英

  Jul. 2018, 日本臨床細胞学会雑誌, 57(4号) (4号), 213 - 216, Japanese

  [Refereed]

  Scientific journal


• 重症妊娠悪阻からWernicke脳症とRefeeding症候群を発症した1例

  箕浦麻陽, 藤田太輔, 佐野匠, 鈴木裕介, 大道正英

  Jul. 2018, 臨床婦人科産科, 72(7号) (7号), 721 - 725, Japanese

  [Refereed]

  Scientific journal


• 超緊急帝王切開術(グレードA)の院内システム構築後の課題 ワーキンググループ発足と病棟内での取り組み

  森村友貴, 宮越咲江, 草刈典子, 灘本武, 日南淳子, 英都貴子, 藤田太輔, 大道正英

  Jun. 2018, 大阪母性衛生学会雑誌, 54(1号) (1号), 134 - 138, Japanese

  [Refereed]

  Scientific journal


• 卵巣悪性腫瘍合併妊娠の1例

  田中サキ, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 大道正英

  May 2018, 産婦人科の進歩, 70(2号) (2号), 89 - 96, Japanese

  [Refereed]

  Scientific journal


• Recombinant human soluble thrombomodulin as an anticoagulation therapy improves recurrent miscarriage and fetal growth restriction due to placental insufficiency – The leading cause of preeclampsia

  Takumi Sano, Yoshito Terai, Atsushi Daimon, Misa Nunode, Yoko Nagayasu, Atsuko Okamoto, Daisuke Fujita, Masami Hayashi, Masahide Ohmichi

  W.B. Saunders Ltd, May 2018, Placenta, 65, 1 - 6, English

  [Refereed]

  Scientific journal


• Foretinib (GSK1363089) induces p53-dependent apoptosis in endometrial cancer

  Yuhei Kogata, Tomohito Tanaka, Yoshihiro J. Ono, Masami Hayashi, Yoshito Terai, Masahide Ohmichi

  Impact Journals LLC, Apr. 2018, Oncotarget, 9(32) (32), 22769 - 22784, English

  [Refereed]

  Scientific journal


• Motivating Mothers to Recommend Their 20-Year-Old Daughters Receive Cervical Cancer Screening: A Randomized Study.

  Tomomi Egawa-Takata, Yutaka Ueda, Akiko Morimoto, Yusuke Tanaka, Asami Yagi, Yoshito Terai, Masahide Ohmichi, Tomoyuki Ichimura, Toshiyuki Sumi, Hiromi Murata, Hidetaka Okada, Hidekatsu Nakai, Masaki Mandai, Shinya Matsuzaki, Eiji Kobayashi, Kiyoshi Yoshino, Tadashi Kimura, Junko Saito, Yumiko Hori, Eiichi Morii, Tomio Nakayama, Mikiko Asai-Sato, Etsuko Miyagi, Masayuki Sekine, Takayuki Enomoto, Yorihiko Horikoshi, Tetsu Takagi, Kentaro Shimura

  BACKGROUND: In Japan, the rate of cervical cancer screening is remarkably low, especially among women in their twenties and thirties, when cervical cancer is now increasing dramatically. The aim of this study was to test whether a modified government reminder for 20-year-old women to engage in cervical cancer screening, acting through maternal education and by asking for a maternal recommendation to the daughter to receive the screening, could increase their participation rate. METHODS: In two Japanese cities, 20-year-old girls who had not received their first cervical cancer screening before October of fiscal year 2014 were randomized into two study arms. One group of 1,274 received only a personalized daughter-directed reminder leaflet for cervical cancer screening. In the second group of 1,274, the daughters and their mothers received a combination package containing the same reminder leaflet as did the first group, plus an additional informational leaflet for the mother, which requested that the mother recommend that her daughter undergo cervical cancer screening. The subsequent post-reminder screening rates of these two study arms were compared. RESULTS: The cervical cancer screening rate of 20-year-old women whose mothers received the information leaflet was significantly higher than that for women who received only a leaflet for themselves (11% vs 9%, P = 0.0049). CONCLUSIONS: An intervention with mothers, by sending them a cervical cancer information leaflet with a request that they recommend that their daughter receive cervical cancer screening, significantly improved their daughters' screening rate.

  Mar. 2018, Journal of epidemiology, 28(3) (3), 156 - 160, English, Domestic magazine

  [Refereed]

  Scientific journal


• 妊娠中子宮頸部円錐切除症例の後方視的解析 子宮頸部円錐切除術の実態調査に関する小委員会(婦人科腫瘍委員会)報告

  古形祐平, 寺井義人, 田中良道, 大道正英, 池田仁惠, 三上幹男, 榎本隆之, 小林陽一, 永瀬智, 横山正俊, 片渕秀隆

  Feb. 2018, 日本産科婦人科学会雑誌, 70(2) (2), 846, Japanese


• 分娩後1年以内の子宮頸部円錐切除症例の後方視的解析 子宮頸部円錐切除術の実態調査に関する小委員会(婦人科腫瘍委員会)報告

  田中良道, 寺井義人, 古形祐平, 大道正英, 池田仁惠, 三上幹男, 榎本隆之, 小林陽一, 永瀬智, 横山正俊, 片渕秀隆

  Feb. 2018, 日本産科婦人科学会雑誌, 70(2) (2), 846, Japanese


• Which is better for predicting pelvic lymph node metastases in patients with cervical cancer: Fluorodeoxyglucose-positron emission tomography/computed tomography or a sentinel node biopsy? A retrospective observational study

  TanakaT, SasakiH, TsuchihashiH, YamamotoK, YamadaT, OhmichiM

  Systematic pelvic lymph node resection may not be needed for patients with cervical cancer, especially in the early stage, if the pre- or intraoperative diagnosis of lymph node status is correct. The aim of this study was to evaluate the diagnostic accuracy of pelvic lymph node metastasis for fluorodeoxyglucose-positron emission tomography/computed tomography (FDG PET/CT) and sentinel node biopsy (SNB) of cervical cancer patients.Forty-eight patients with cervical cancer were imaged with FDG PET/CT before radical hysterectomy and underwent an SNB followed by systematic pelvic lymph node dissection. The diagnostic accuracy for predicting pelvic node metastases for FDG PET/CT and SNB compared with the ultimate histologic status was analyzed.Among 96 hemi-pelvises (HPs) in 48 patients, pelvic lymph node metastases were obtained in 12 HPs. The sensitivity of pelvic node metastases for FDG PET/CT and SNB was 8.3% and 75.0%, respectively. The specificity for FDG PET/CT and SNB was 97.6% and 94.0%, respectively. The negative predictive value for FDG-PET/CT and SNB was 88.2% and 100%, respectively.SNB is more suitable for detecting pelvic node metastases than FDG PET/CT. The omission of systematic pelvic lymphadenectomy should be considered based on the findings of SNB, not FDG PET/CT.

  2018, Medicine (Baltimore), 97(16) (16), e - 0410, English, International magazine

  [Refereed]

  Scientific journal


• Time-dependent changes of the intention of mothers in Japan to inoculate their daughters with the HPV vaccine after suspension of governmental recommendation.

  Asami Yagi, Yutaka Ueda, Yusuke Tanaka, Ruriko Nakae, Reisa Kakubari, Akiko Morimoto, Yoshito Terai, Masahide Ohmichi, Tomoyuki Ichimura, Toshiyuki Sumi, Hiromi Murata, Hidetaka Okada, Hidekatsu Nakai, Noriomi Matsumura, Kiyoshi Yoshino, Tadashi Kimura, Junko Saito, Sayaka Ikeda, Mikiko Asai-Sato, Etsuko Miyagi, Masayuki Sekine, Takayuki Enomoto, Kei Hirai, Yorihiko Horikoshi, Tetsu Takagi, Kentaro Shimura

  In Japan, the trend for cervical cancer at younger ages has been increasing. As a countermeasure, the HPV vaccine was introduced as a routine vaccination in April 2013. However, the Ministry of Health, Labour and Welfare (MHLW) announced a "Suspension of its active inoculation recommendation for HPV vaccine" in June 2013. In 2016, 32 months after that suspension, we conducted survey via Internet and compared the results with our previous ones conducted at 9 and 23 months after suspension (in 2014 and 2015, respectively). We examined the 'time-dependent change' of the 'intention of mothers to inoculate their daughters with the HPV vaccine' in terms of efficacy of external decision-making support. 17.5% of mothers in the first survey replied that they would inoculate their daughters under the current circumstances, 12.1% in the second survey, and 6.7% in the third, showing a consistent decrease in willingness over time (p = 0.03, p < 0.01). If the government recommendation were to be reintroduced, 22.5% of mothers in the first survey replied they would inoculate their daughters, 21.0% in the second survey, which indicated no significant difference (p = 0.65) over the first interval; however, this was significantly decreased to 12.2% in the third survey (p < 0.01). Our study revealed that the intention to inoculate their daughters has been declining among Japanese mothers over time triggered by the suspension.

  2018, Human vaccines & immunotherapeutics, 14(10) (10), 2497 - 2502, English, International magazine

  [Refereed]

  Scientific journal


• The detection of sentinel lymph nodes in laparoscopic surgery can eliminate systemic lymphadenectomy for patients with early stage endometrial cancer

  TanakaT, FujiwaraS, TanakaY, SasakiH, TsunetohS, YamamotoK, YamadaT, OhmichiM

  BACKGROUND: The examination of a sentinel lymph node (SLN), where lymph node metastasis first occurs, may be advocated as an alternative staging technique. The aim of this study was to evaluate the feasibility and detection rates of an SLN biopsy in patients with endometrial cancer. STUDY DESIGN: Two hundred and eleven patients with endometrial cancer underwent an SLN biopsy at hysterectomy using three kinds of tracers including 99m-technetium-labeled tin colloid (99mTc), indigo carmine and indocyanine green. Factors related to the side-specific detection rate, sensitivity and false negative rate were analyzed. RESULTS: The detection rates of the SLN biopsy using 99mTc, indigo carmine and indocyanine green were 77.9, 17.0 and 73.4%, respectively. The detection rate was lower in elderly patients (≥60 years) (67.9 vs 89.2%, p < 0.01), patients with >50% myometrial invasion (68.3 vs 85.2%, p < 0.01), patients with high-grade tumors (69.5 vs 84.9%, p < 0.01) and patients who underwent laparotomy (71.2 vs 84.9%, p < 0.01). There were no significant differences in body mass index. The sensitivity was not significantly different in any factor. However, the false negative rate was higher in patients with > 50% myometrial invasion (11.5 vs 1.2%, p < 0.01), high-grade tumors (13.3 vs 0.8%, p < 0.01) and who underwent laparotomy (12.2 vs 0.4%, p < 0.01). CONCLUSION: Patients who underwent laparoscopy with < 50% myometrial invasion and low-grade tumors not only have higher detection rates, but also have lower false negative rates. These patients may avoid systemic lymphadenectomy according to the status of the SLN biopsy.

  2018, Int J Clin Oncol, 23(2) (2), 305 - 313, English, Domestic magazine

  [Refereed]

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Comparison of the impact of laparoscopic endometriotic cystectomy and vaporization on postoperative serum anti-Mullerian hormone levels

  SaitoN, YamashitaY, OkudaK, KokunaiK, OhmichiM

  2018, Asian J Endosc Surg, 11(1) (1), 23 - 29, English

  [Refereed]

  Scientific journal


• 卵巣癌患者における子宮内膜症癌化と脂質代謝の検討

  丸岡 寛, 佐々木 浩, 土橋 裕充, 中村 奈津穂, 多賀 紗也香, 藤原 聡枝, 田中 良道, 田中 智人, 恒遠 啓示, 寺井 義人, 大道 正英

  (一社)日本女性医学学会, Oct. 2017, 日本女性医学学会雑誌, 25(Suppl.) (Suppl.), 167 - 167, Japanese


• Intraperitoneal cytology after laparoscopic hysterectomy in patients with endometrial cancer A retrospective observational study

  Tomohito Tanaka, Yoshito Terai, Kazuya Maeda, Keisuke Ashihara, Yuhei Kogata, Hiroshi Maruoka, Shinichi Terada, Takashi Yamada, Masahide Ohmichi

  Jul. 2017, MEDICINE, 96(27) (27), English

  [Refereed]

  Scientific journal


• CD24 expression is a marker for predicting clinical outcome and regulates the epithelial-mesenchymal transition in ovarian cancer via both the Akt and ERK pathways.

  Kiyoko Nakamura, Yoshito Terai, Akiko Tanabe, Yoshihiro J Ono, Masami Hayashi, Kazuya Maeda, Satoe Fujiwara, Keisuke Ashihara, Michihiko Nakamura, Yoshimichi Tanaka, Tomohito Tanaka, Satoshi Tsunetoh, Hiroshi Sasaki, Masahide Ohmichi

  The degree of peritoneal dissemination and chemotherapy-resistant tumors is related to the prognosis in patients with advanced-stage ovarian cancer. The epithelial-mesenchymal-transition (EMT) is a multifaceted pathological program that endows cancer cells with the ability to invade and disseminate. CD24 is frequently overexpressed in various human cancers and is correlated with a poor prognosis. We herein examined the functions of CD24 in human ovarian cancer cell lines and evaluated how it contributes to the molecular mechanism underlying the regeneration of cancer stem-like cells (CSCs) through the EMT mechanism in ovarian carcinoma. We demonstrated that CD24 was expressed in 70.1% of primary ovarian carcinoma tissues, which were obtained from 174 patients, and that the expression of CD24 was an independent predictor of survival in patients with ovarian cancer. The expression of CD24 has been found to be correlated with the FIGO stage, presence of peritoneal and lymph node metastasis. CD24 induces the EMT phenomenon, which is involved in cell invasion, the highly proliferative phenotype, colony formation and which is associated with cisplatin resistance and the properties of CSCs, via the activation of PI3K/Akt, NF-κB and ERK in Caov-3 cisplatin-resistant cell lines. CD24-positive ovarian carcinomas have been shown to have a greater potential for intra-abdominal tumor cell dissemination in in vivo models. Our findings suggest that CD24 induced the EMT phenomenon in ovarian cancer, and that CD24 amplified cell growth-related intracellular signaling via the PI3K/Akt and MAPK pathways by affecting the EMT signal pathways. We believe that CD24 is a key molecule of metastatic progression in the EMT phenomenon and a promising therapeutic target for advanced ovarian cancer.

  Jun. 2017, Oncology reports, 37(6) (6), 3189 - 3200, English, International magazine

  Scientific journal


• Comparison between laparoscopy and laparotomy in systematic para-aortic lymphadenectomy for patients with endometrial cancer: A retrospective multicenter study

  Tomohito Tanaka, Yoshito Terai, Shigenori Hayashi, Daisuke Aoki, Michiyasu Miki, Eiji Kobayashi, Tadashi Kimura, Tsukasa Baba, Noriomi Matsumura, Masahide Ohmichi

  Mary Ann Liebert Inc., Jun. 2017, Journal of Gynecologic Surgery, 33(3) (3), 105 - 110, English

  [Refereed]

  Scientific journal


• Lower FOXO3 mRNA expression in granulosa cells is involved in unexplained infertility.

  Hikaru Yamamoto, Yoshiki Yamashita, Natsuho Saito, Atsushi Hayashi, Masami Hayashi, Yoshito Terai, Masahide Ohmichi

  AIM: The aim of this study was to investigate whether FOXO1 and FOXO3 mRNA expression in granulosa cells is the cause of unexplained infertility. METHODS: Thirty-one patients aged <40 years (13 with unexplained infertility and 18 with male partner infertility as a control group) whose serum anti-Müllerian hormone level was >0.5 ng/μL were enrolled in the study. All patients underwent oocyte retrieval under a short protocol from June 2012 to October 2013. Real-time PCR was carried out using mRNA extracted from granulosa cells retrieved from mature follicles. We compared FOXO1 and FOXO3 mRNA expression ratios in granulosa cells between the unexplained infertility group and the male infertility group. The relation between FOXO1 and FOXO3 mRNA expression ratios in granulosa cells and assisted reproduction technology clinical outcome was also examined. RESULTS: FOXO3 mRNA expression ratio was significantly lower in the unexplained infertility group than in the male infertility group. Moreover, FOXO3 mRNA expression ratio showed a positive correlation with both the number of retrieved oocytes and serum anti-Müllerian hormone level. A positive correlation was also identified between FOXO1 mRNA expression and total dose of hMG. As well, the number of retrieved oocytes in the unexplained infertility group was statistically lower than that in the male infertility group. CONCLUSION: A lower FOXO3 mRNA expression in granulosa cells leads to poor oocyte development in patients with unexplained infertility undergoing controlled ovarian stimulation for in vitro fertilization-embryo transfer.

  Jun. 2017, The journal of obstetrics and gynaecology research, 43(6) (6), 1021 - 1028, English, International magazine

  Scientific journal


• The detection of sentinel lymph nodes in laparoscopic surgery for uterine cervical cancer using 99m-technetium-tin colloid, indocyanine green, and blue dye.

  Tomohito Tanaka, Yoshito Terai, Keisuke Ashihara, Satoshi Tsunetoh, Hiroyuki Akagi, Takashi Yamada, Masahide Ohmichi

  OBJECTIVE: Our objective was to determine the feasibility and detection rates and clarify the most effective combination of injected tracer types for sentinel lymph node (SLN) mapping in uterine cervical cancer in patients who have undergone laparoscopic surgery or neoadjuvant chemotherapy (NAC). METHODS: A total of 119 patients with cervical cancer underwent SLN biopsy at radical hysterectomy using three types of tracers. The various factors related to side-specific detection rate, sensitivity, and false negative (FN) rate were analyzed. RESULTS: The SLN detection rates using 99m-technetium ((99m)Tc)-tin colloid, indigo carmine, and indocyanine green (ICG) were 85.8%, 20.2%, and 61.6%, respectively. The patients with ≥2-cm-diameter tumors and those who received NAC had lower detection rates than those with <2-cm-diameter tumors (75.7% vs. 91.5%, p<0.01) and those who did not receive NAC (67.9% vs. 86.3%, p<0.01), respectively. Laparoscopic procedures had a higher detection rate than laparotomy (100.0% vs. 77.1%, p<0.01). No factors significantly affected the sensitivity; however, the patients with ≥2-cm-diameter tumors (86.0% vs. 1.4%, p<0.01), NAC (19.4% vs. 2.2%, p<0.01), and those who underwent laparotomy (7.4% vs. 0%, p<0.01) had an unfavorable FN rate. CONCLUSION: Among the examined tracers, (99m)Tc had the highest detection of SLN mapping in patients with uterine cervical cancer. Patients with local advanced cervical cancer with/without NAC treatment might be unsuited for SLN mapping. SLN mapping is feasible and results in an excellent detection rate in patients with <2-cm-diameter cervical cancer. Laparoscopic surgery is the best procedure for SLN detection in patients with early-stage disease.

  Mar. 2017, Journal of gynecologic oncology, 28(2) (2), e13, English, International magazine

  Scientific journal


• Micro RNA-22を介した子宮頸癌の分子標的治療への応用

  中村 真由美, 林 正美, 橋田 宗祐, 丸岡 寛, 小西 博巳, 前田 和也, 田中 良道, 佐々木 浩, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2017, 日本産科婦人科学会雑誌, 69(2) (2), 664 - 664, Japanese


• The efficacy of the cyclin-dependent kinase 4/6 inhibitor in endometrial cancer.

  Tomohito Tanaka, Yoshito Terai, Keisuke Ashihara, Satoe Fujiwara, Yoshimichi Tanaka, Hiroshi Sasaki, Satoshi Tsunetoh, Masahide Ohmichi

  BACKGROUND: PD-0332991, the selective cyclin-dependent kinase 4/6 inhibitor palbociclib, causes cell cycle arrest by inhibiting phosphorylation of retinoblastoma (Rb) protein. The aim of this study was to evaluate the therapeutic potential of PD-0332991 in endometrial cancer. METHODS AND FINDINGS: Four human endometrial cancer cell lines, ECC, HEC1A, HEC108 and TEN, were treated with PD-0332991 and their function was evaluated. In vivo, the therapeutic efficacy was evaluated in a model of subcutaneous endometrial cancer. An immunohistochemical analysis was performed in 337 endometrial cancer specimens. A proliferation assay revealed that 2 of the 4 cell lines that expressed Rb were sensitive to PD-0332991 with an IC50 of 0.65 μM (HEC1A) and 0.58 μM (HEC108), respectively. Both cell lines had G0/G1 cell cycle arrest after treatment with PD-0332991 according to flow cytometry. In vivo, PD-0332991 had antitumoral efficacy with a reduction in the activity of Ki67 and phosphorylation of Rb. Immunohistochemical analyses revealed that the positive rate of Rb was 67.7%, however, there was no significant relationship between the expression levels of Rb and the tumor grade. CONCLUSIONS: PD-0332991 had therapeutic potential against endometrial cancer cell lines expressing Rb protein. Our immunohistochemical analysis revealed that approximately 70% of patients with endometrial cancer might have therapeutic indications for PD-0332991. Of note, the tumor grade had no impact on the indications for treatment.

  2017, PloS one, 12(5) (5), e0177019, English, International magazine

  Scientific journal


• A case of tuberculous peritonitis diagnosed with a laparoscope

  ASHIHARA Keisuke, MIYAMOTO Shunsuke, KOGATA Yuhei, FUJIWARA Satoe, TANAKA Tomohito, TSUNETOH Satoshi, TERAI Yoshito, OHMICHI Masahide

  It is difficult to diagnose patients with tuberculous peritonitis (TP) through a clinical examination. We herein report a case of TP diagnosed with a laparoscope. A 66-year-old female presented with weight loss, a low-grade fever and abdominal pain. Her serum CA125 level was 2010 U/ml. Computed tomography showed a thickened peritoneum and a large amount of ascites, which suggested that the patient had ovarian or peritoneal cancer. Mycobacterium tuberculosis was negative in culture from sputum and ascites. Laparoscopic surgery was performed to make a correct diagnosis, during which the bilateral ovaries were found to have no swelling, and macroscopic nodules were found on the peritoneum. A histological examination showed the presence of epithelioid granulomas with typical Langhans cells with areas of caseous necrosis. The patient finally diagnosed with peritoneal tuberculosis. Treatment with anti-tuberculosis drugs was started, with the combined use of isoniazid, rifampicin, ethambutol, and pyrazinamide. A laparoscope can be helpful for the diagnosis of TP. [Adv Obstet Gynecol, 69(2): 145-150, 2017 (H29.5)]

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2017, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 69(2) (2), 145 - 150, Japanese


• Successful laparoscopic management of primary peritoneal pregnancy: a case report

  MIYAMOTO Shunsuke, TANAKA Tomohito, TERADA Shinichi, KOGATA Yuhei, ASHIHARA Keisuke, HAYASHI Atsushi, TERAI Yoshito, OHMICHI Masahide

  Approximately 1% of ectopic pregnancies are peritoneal and could be life threatening. We present the case of a peritoneal pregnancy treated with laparoscopic surgery. A 29-year-old woman with abdominal pain and vaginal bleeding was suspected of a ruptured ectopic pregnancy on the basis of a trans-vaginal ultrasound. Emergency laparoscopic surgery was then performed. During the surgery, a gestational sac with blood clot was found on the vesico-uterine pouch and was completely resected. Primary peritoneal pregnancy was diagnosed after the surgery. Laparoscopic surgery could be useful for the treatment of peritoneal pregnancies as well as for the diagnosis of unusually located ectopic pregnancies. [Adv Obstet Gynecol, 69 (4):355-359, 2017 (H29.10)]

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2017, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 69(4) (4), 355 - 359, Japanese


• Analyzing the risk factors for a diminished oocyte retrieval rate under controlled ovarian stimulation.

  Mayumi Nakamura, Yoshiki Yamashita, Atsushi Hayashi, Natsuho Saito, Masae Yu, Masami Hayashi, Yoshito Terai, Masahide Ohmichi

  Aim: To investigate which risk factors contribute to a lower oocyte retrieval ratio in women who are receiving controlled ovarian hyperstimulation. Methods: The authors retrospectively analyzed 329 in vitro fertilization (IVF) cycles under controlled ovarian hyperstimulation by using a gonadotropin-releasing hormone antagonist or agonist at Osaka Medical College, Japan. The patients were classified into five groups: advanced age, male infertility, severe endometriosis, tubal infertility, and unexplained infertility. The primary outcomes were the patients' age, oocyte retrieval ratio, serum basal follicle-stimulating hormone, total dose of gonadotropin, and the clinical outcome. A secondary outcome was the stepwise multivariate logistic regression analysis to assess the factors associated with the failure of oocyte retrieval. Results: The oocyte retrieval ratio declined significantly with the patient's age. The ratio of endometriosis in unsuccessful cases was significantly higher than that in successful cycles. Advanced age and endometriosis were the factors that were significantly associated with a lowered oocyte retrieval rate. Conclusion: Advanced age and endometriosis are high-risk factors that contribute to oocyte retrieval failure in infertile patients who are receiving IVF treatment.

  Jan. 2017, Reproductive medicine and biology, 16(1) (1), 40 - 44, English, Domestic magazine

  Scientific journal


• Bone Marrow-Derived Endothelial Progenitor Cells Reduce Recurrent Miscarriage in Gestation.

  Kanki K, Ii M, Terai Y, Ohmichi M, Asahi M

  Dec. 2016, Cell transplantation, 25(12) (12), 2187 - 2197

  [Refereed]


• リンパ浮腫に対する術前リンパシンチグラフィーの有用性について

  橋田 宗祐, 芦原 敬允, 前田 和也, 藤原 聡枝, 田中 智人, 田中 良道, 恒遠 啓示, 寺井 義人, 大道 正英, 塗 隆志, 上田 晃一

  「産婦人科の進歩」編集室, Oct. 2016, 産婦人科の進歩, 68(4) (4), 492 - 492, Japanese


• 卵巣チョコレート嚢胞の術後再発

  劉 昌恵, 林 篤史, 中村 真由美, 芦原 敬允, 小野 賀大, 林 正美, 寺井 義人, 大道 正英

  「産婦人科の進歩」編集室, Aug. 2016, 産婦人科の進歩, 68(3) (3), 350 - 353, Japanese


• 子宮体癌に対する腹腔鏡下傍大動脈リンパ節郭清の有用性に関する多施設共同研究

  林 茂徳, 山下 博, 寺井 義人, 田中 智人, 馬場 長, 小林 栄仁, 三木 通保

  (公社)日本婦人科腫瘍学会, Jun. 2016, 日本婦人科腫瘍学会雑誌, 34(3) (3), 431 - 431, Japanese


• A case of Sertoli cell tumor in a postmenopausal woman

  MURAYAMA Yumi, TANAKA Yoshimichi, TANAKA Tomohito, TSUNETOH Satoshi, SASAKI Hiroshi, KANEMURA Masanori, TERAI Yoshito, OHMICHI Masahide

  Sertoli-Leydig cell tumor belongs to the group of sex cord-stromal tumors of the ovary. They are very rare tumors and account for about 0.2-0.6 % of all ovarian tumors. Age at diagnosis averages 25 years, with 75% of these tumors occurring during the second and third decade of life, and less than 10% occurring either prior to menarche or after menopause. We present a case of a Sertoli cell tumor in a postmenopausal woman with signs of virilization. A 67-year-old nulliparous woman presented to our attention with the chief complaint of abdominal distension. Her past history was endometriosis, gout, hypertension and hepatitis C. Cervical cytology was NILM. A magnetic resonance image scan of the pelvic area revealed a 25 cm complex cystic and solid right pelvic mass. As well, the endometrium of the uterus was unusually thick. Serum estradiol was 163.6 pg/ml and serum testosterone was 5.6 ng/ml. We suspected a hormone producing ovarian tumor and performed an abdominal total hysterectomy, bilateral salpingo-oophorectomy and partial omentectomy. The tumor was cystic and solid right ovarian tumor. The predominant microscopic pattern was albeit or retiform. A mitotic count was 1-2/10 HPFs. The immunohistochemical findings showed α-inhibin, vimentin and PgR were positive, EMA, CEA, AE1/AE3, CK7, CK20, CD30, AFP, ER were negative, MIB-1 was positive in 1% of tumor. Leydig cells were not observed. Final diagnosis was right ovarian tumor, Sertoli cell tumor (intermediate differentiation, borderline malignancy) pT1a NX M0, FIGO stage1A. After the surgery, the level of serum estradiol and testosterone decreased rapidly. The patient was started on follow-up visits without adjuvant therapy and was found to be with no evidence of disease. [Adv Obstet Gynecol, 68(1) : 36-41 , 2016(H28.2)]

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2016, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 68(1) (1), 36 - 41, Japanese


• A Case of Intestinal Obstruction in Pregnancy Diagnosed by MRI and Treated by Intravenous Hyperalimentation.

  Atsushi Daimon, Yoshito Terai, Yoko Nagayasu, Atsuko Okamoto, Takumi Sano, Yusuke Suzuki, Kazuyoshi Kanki, Daisuke Fujita, Masahide Ohmichi

  Intestinal obstruction in pregnancy is rare and is mainly caused by prior pelvic surgery. We herein report a case of intestinal obstruction in a pregnant female with a history of laparoscopic myomectomy, who presented with hypogastric pain, abdominal distension, and vomiting at 26 weeks of gestation. A simple intestinal obstruction was diagnosed by MRI. Conservative treatments, including intravenous hyperalimentation and the placement of an ileus tube, were provided and her abdominal symptoms improved for 14 days. After restarting oral intake, she had no abdominal symptoms. She gave birth to a 2,146 g female infant by caesarean section at 37 weeks and 1 day of gestation. Although an area of cicatrization, which was thought to have been the starting point of the occlusion that caused the intestinal obstruction, was found, the excision of the small intestine was not necessary. Her postoperative course was uneventful. Intestinal obstruction requires a prompt diagnosis and aggressive intervention may be necessary to minimize the morbidity and mortality associated with this rare complication of pregnancy. MRI can be safely used during pregnancy to diagnose intestinal obstruction and intravenous hyperalimentation may improve the maternal and fetal prognoses.

  2016, Case reports in obstetrics and gynecology, 2016, 8704035 - 8704035, English, International magazine

  Scientific journal


• CD24 expression as a marker for predicting clinical outcome and invasive activity in uterine cervical cancer.

  Tomohito Tanaka, Yoshito Terai, Yuhei Kogata, Keisuke Ashihara, Kazuya Maeda, Satoe Fujiwara, Saha Yoo, Yoshimichi Tanaka, Satoshi Tsunetoh, Hiroshi Sasaki, Masanori Kanemura, Akiko Tanabe, Masahide Ohmichi

  CD24, a small heavily glycosylated mucin-like glycosyl-phosphatidylinositol-anchored cell surface protein, plays an important role in the carcinogenesis of various human malignancies. However, its function in cervical cancer remains unclear. The aim of the present study was to evaluate the expression of CD24 clinicopathologically and to analyze its functional behavior biologically in cervical cancer. A total of 117 uterine cervical cancer tumors were immunohistochemically analyzed using a CD24 monoclonal antibody on paraffin blocks. We also examined whether CD24 enhanced the invasive activity or the Akt, ERK, NF-κB and MMP activity in a uterine cervical cancer cell line (CaSki) by a western blot analysis. The patients with enhanced CD24 expression had a higher rate of advanced clinical stage (50 vs. 16.5%, p<0.01), lymph node metastasis (34.6 vs. 14.3%) and lymphovascular involvement (65.4 vs. 20.4%, p=0.01), and a poor overall and disease-free survival (5-year survival rate: 62 vs. 86%, p=0.03). CD24 overexpression in CaSki cells resulted in activation of Cell Signaling proteins, including Akt, ERK, NF-κB and MMP-9. An invasion assay showed that CD24 overexpression in CaSki cells led to increased invasion ability. The CD24 overexpression also increased mRNA expression of Slug but not Snail. Moreover, the CD24 overexpression also decreased expression of E-cadherin and increased N-cadherin protein levels. Increased expression of CD24 may be associated with tumor progression and prognosis in patients with uterine cervical cancer. CD24 expression may therefore be used not only as a prognostic marker in uterine cervical cancer, but also as a target for the development of new therapeutic approaches.

  Nov. 2015, Oncology reports, 34(5) (5), 2282 - 8, English, International magazine

  Scientific journal


• Hepatocyte growth factor secreted by ovarian cancer cells stimulates peritoneal implantation via the mesothelial-mesenchymal transition of the peritoneum.

  Michihiko Nakamura, Yoshihiro J Ono, Masanori Kanemura, Tomohito Tanaka, Masami Hayashi, Yoshito Terai, Masahide Ohmichi

  OBJECTIVE: A current working model for the metastatic process of ovarian carcinoma suggests that cancer cells are shed from the ovarian tumor into the peritoneal cavity and attach to the layer of mesothelial cells that line the inner surface of the peritoneum, and several studies suggest that hepatocyte growth factor (HGF) plays an important role in the dissemination of ovarian cancer. Our objectives were to evaluate the HGF expression of ovarian cancer using clinical data and assess the effect of HGF secreted from human ovarian cancer cells to human mesothelial cells. METHODS: HGF expression was immunohistochemically evaluated in 165 epithelial ovarian cancer patients arranged as tissue microarrays. HGF expression in four ovarian cancer cell lines was evaluated by using semi-quantitative polymerase chain reaction, Western blotting and enzyme-linked immunosorbent assay. The effect of ovarian cancer cell derived HGF to the human mesothelial cells was assessed by using morphologic analysis, Western blotting and cell invasion assay. The effect of HGF on ovarian cancer metastasis was assessed by using in vivo experimental model. RESULTS: The clinical data showed a significantly high correlation between the HGF expression and the cancer stage. The in vivo and in vitro experimental models revealed that HGF secreted by ovarian cancer cells induces the mesothelial-to-mesenchymal transition and stimulates the invasion of mesothelial cells. Furthermore, manipulating the HGF activity affected the degree of dissemination and ascite formation. CONCLUSIONS: We demonstrated that HGF secreted by ovarian cancer cells plays an important role in cancer peritoneal implantation.

  Nov. 2015, Gynecologic oncology, 139(2) (2), 345 - 54, English, International magazine

  Scientific journal


• The effect of moderate to severe endometriosis on expression of growth differentiation factor-9 mRNA in human granulosa cells under controlled ovarian hyperstimulation.

  Sachiko Kawabe, Yoshiki Yamashita, Natsuho Saito, Kana Kokunai, Atsushi Hayashi, Masami Hayashi, Yoshito Terai, Kazunori Miyazaki, Masahide Ohmichi

  Purpose: To investigate the effect of moderate to severe endometriosis on mRNA expression of growth differentiation factor-9 (GDF-9) in the granulosa cells of mature follicles. Methods: Follicular fluid (FF) was obtained from 13 patients with moderate to severe endometriosis and 11 without endometriosis, as a control group, and GDF-9 protein levels in both were assayed by western blotting. mRNA expression by GDF-9 and LH receptor (LHR) in granulosa cells obtained from all patients in the study were investigated by StepOne Real-Time PCR. Results: Although GDF-9 in FF from patients with endometriosis was no different from that of controls, GDF-9 mRNA expression in granulosa cells of patients with endometriosis was statistically significantly lower than for the control group. The number of oocytes and high-quality embryos was positively correlated with GDF-9 mRNA expression in controls but not in patients with endometriosis Moreover, a negative correlation was identified between GDF-9 mRNA expression and serum estrogen and progesterone levels in the control group, whereas no correlation was observed for the endometriosis group. Conclusions: Moderate to severe endometriosis can significantly reduce GDF-9 mRNA expression in the granulosa cells of patients with the disease compared with those without, thus causing poor oocyte maturation and lower embryo quality.

  Oct. 2015, Reproductive medicine and biology, 14(4) (4), 179 - 184, English, Domestic magazine

  Scientific journal


• 卵巣チョコレート嚢胞の術後再発

  劉 昌恵, 林 篤史, 中村 真由美, 小野 賀大, 林 正美, 寺井 義人, 大道 正英

  「産婦人科の進歩」編集室, Oct. 2015, 産婦人科の進歩, 67(4) (4), 522 - 522, Japanese


• Met Signaling Cascade Is Amplified by the Recruitment of Phosphorylated Met to Lipid Rafts via CD24 and Leads to Drug Resistance in Endometrial Cancer Cell Lines.

  Yoshihiro Joshua Ono, Akiko Tanabe, Tomohito Tanaka, Yoshimichi Tanaka, Masami Hayashi, Yoshito Terai, Masahide Ohmichi

  Endometrial cancer is the most prevalent gynecologic cancer in the Western world, and the number of advanced chemotherapy-resistant cancers is increasing with the absolute increase in patients. The development of resistance to chemotherapeutic drugs by cancer cells represents a major challenge in the clinical cure of advanced and metastatic cancers. CD24 has been reported to be a marker for a poor prognosis in several tumors, and we herein examined the functions of CD24 in human endometrioid adenocarcinoma cell lines and evaluated how it contributes to cancer drug resistance. We demonstrated that CD24 was responsible for the recruitment of phosphorylated Met to the lipid raft domain of the cell membrane, resulting in amplification of the Met signaling cascade, ultimately leading endometrial cancer cells to express higher levels of ATP-binding cassette (ABC) transporters. Our findings suggest that CD24-mediated amplification of the Met cascade may contribute to the drug resistance of endometrial cancer.

  Oct. 2015, Molecular cancer therapeutics, 14(10) (10), 2353 - 63, English, International magazine

  Scientific journal


• 卵巣ブレンナー腫瘍を細胞診で診断し得た1例

  服部 公亮, 山田 隆司, 明石 静香, 中山 裕子, 浦上 真由美, 武田 玲郁, 出口 千尋, 棚田 諭, 石崎 幸恵, 廣瀬 善信, 橋田 宗祐, 藤原 聡枝, 金村 昌徳, 寺井 義人, 大道 正英

  (公社)日本臨床細胞学会, Oct. 2015, 日本臨床細胞学会雑誌, 54(Suppl.2) (Suppl.2), 565 - 565, Japanese


• Mitotically active cellular fibroma of the ovary: a case report and literature review.

  Yamada T, Hattori K, Satomi H, Hirose Y, Nakai G, Daimon A, Hayashi A, Terai Y, Ohmichi M, Fukunaga M

  Oct. 2015, Journal of ovarian research, 8, 65

  [Refereed]


• Estradiol-mediated hepatocyte growth factor is involved in the implantation of endometriotic cells via the mesothelial-to-mesenchymal transition in the peritoneum.

  Yoshihiro J Ono, Masami Hayashi, Akiko Tanabe, Atsushi Hayashi, Masanori Kanemura, Yoshito Terai, Masahide Ohmichi

  The pathogenesis of endometriosis, a chronic painful gynecological disease characterized by the presence of endometrial tissue located outside of the uterus and often adhering to the peritoneum, is known to be estrogen dependent. However, the precise pathophysiology of endometriosis remains elusive. Recent studies indicate that the epithelial-to-mesenchymal transition (EMT) of human endometrial cells is important for the progression of endometriosis, and another previous study has implicated hepatocyte growth factor (HGF) in endometriosis progression. The aim of the present study was to examine the role of estradiol in the regulation of HGF production and progression of peritoneal endometriosis, focusing on the interactions between the peritoneum and endometriotic cells. Consequently, estradiol was found to promote the proliferation, invasion, and migration of immortalized human endometrial epithelial cells (hEECs) via HGF upregulation, and the estradiol-induced direct binding of estrogen receptor-α to the HGF promoter was confirmed on a chromatin immunoprecipitation (ChIP) assay. Estradiol also induced the EMT in hEECs by promoting HGF production. Furthermore, human mesothelial cells underwent the mesothelial-to-mesenchymal transition (MMT) during culture with estradiol-stimulated hEEC conditioned medium. Importantly, estradiol itself did not induce the MMT, and the estradiol-stimulated hEEC-conditioned medium in the presence of HGF antibodies reversed the MMT process. These results, which were obtained using immortalized hEECs, indicate that estradiol-induced HGF production may play a crucial role in the peritoneal implantation of human endometriotic cells by exerting proliferative and invasive effects via the EMT in hEECs and promoting the MMT in mesothelial cells.

  Jun. 2015, American journal of physiology. Endocrinology and metabolism, 308(11) (11), E950-9, English, International magazine

  Scientific journal


• Preoperative MRI and Intraoperative Frozen Section Diagnosis of Myometrial Invasion In Patients With Endometrial Cancer

  Tomohito Tanaka, Yoshito Terai, Yoshihiro J. Ono, Satoe Fujiwara, Yoshimichi Tanaka, Hiroshi Sasaki, Satoshi Tsunetoh, Masanori Kanemura, Kazuhiro Yamamoto, Takashi Yamada, Masahide Ohmichi

  Jun. 2015, INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 25(5) (5), 879 - 883, English

  [Refereed]

  Scientific journal


• 卵巣粘液性境界悪性腫瘍(内頸部様)の1例

  服部 公亮, 山田 隆司, 明石 静香, 橋田 宗祐, 藤原 聡恵, 佐々木 浩, 金村 昌徳, 寺井 義人, 大道 正英, 廣瀬 善信

  (公社)日本臨床細胞学会, Apr. 2015, 日本臨床細胞学会雑誌, 54(Suppl.1) (Suppl.1), 311 - 311, Japanese


• Genitofemoral neuropathy after pelvic lymphadenectomy in patients with uterine corpus cancer.

  Tomohito Tanaka, Yoshito Terai, Yoshihiro J Ono, Satoe Fujiwara, Yoshimichi Tanaka, Hiroshi Sasaki, Satoshi Tsunetoh, Masanori Kanemura, Masahide Ohmichi

  OBJECTIVE: The aim of this study was to estimate the incidence, etiology, and outcomes of genitofemoral neuropathy after pelvic lymphadenectomy (PLD) for uterine corpus cancer. MATERIALS AND METHODS: The medical records of women who underwent PLD for uterine corpus cancer between June 2001 and June 2013 were reviewed. Information regarding neuropathy was directly reported by each subject. RESULTS: Thirty-two of 300 patients undergoing PLD during the defined period experienced postoperative neuropathy due to genitofemoral nerve injury, for an incidence of 10.7%. The patients treated with PLD with para-aortic lymphadenectomy (PALD) exhibited a lower rate of genitofemoral neuropathy than those treated without PALD (4.3% vs 13.5%, P = 0.01). The laparoscopy group displayed a higher rate of genitofemoral neuropathy than the laparotomy group (19.1% vs 9.1%, P = 0.04). A total of 81.3% of the patients experienced a full recovery, with a medium time to resolution of 6 months (3-12 months). The administration of adjuvant chemotherapy, including paclitaxel, did not extend the time to recovery. CONCLUSIONS: Neuropathy resulting from genitofemoral nerve injury is not infrequent; however, most of the patients recover completely. In this study, the use of laparoscopic procedures increased the incidence of genitofemoral neuropathy, whereas that of PALD did not.

  Mar. 2015, International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 25(3) (3), 533 - 6, English, International magazine

  Scientific journal


• A case of gastric-type adenocarcinoma of the uterine cervix associated with lobular endocervical glandular hyperplasia: radiologic-pathologic correlation.

  Takahiro Tsuboyama, Kazuhiro Yamamoto, Go Nakai, Takashi Yamada, Satoe Fujiwara, Yoshito Terai, Masahide Ohmichi, Yoshifumi Narumi

  Gastric-type adenocarcinoma (GAS) of the uterine cervix is a recently defined subtype of mucinous adenocarcinoma. GAS is proposed to include minimal deviation adenocarcinoma (MDA) as a very well-differentiated form and has been suggested to arise from lobular endocervical glandular hyperplasia (LEGH). We report the magnetic resonance imaging (MRI) findings of a GAS associated with LEGH. On MRI, the LEGH component was detected as multiple cystic lesions arranged in a "cosmos pattern", while the GAS was depicted as a predominantly solid lesion containing obvious adenocarcinoma and MDA components, which appeared as mass-like and infiltrative components, respectively. The GAS exhibited tiny cysts on three-dimensional T2-weighted images, high intensity on diffusion-weighted images mostly due to T2 shine-through effect according to apparent diffusion coefficient (ADC) map, and reticular enhancement on dynamic contrast-enhanced MRI, which reflected numerous dilated glandular structures of the tumor. Low ADC was only observed at the deepest invasion front of the obvious adenocarcinoma component. Our case suggests that the MRI features of GAS vary depending on the tumor's histological components, and it is important to be aware of these imaging features when evaluating LEGH on MRI.

  Mar. 2015, Abdominal imaging, 40(3) (3), 459 - 65, English, International magazine

  Scientific journal


• 卵巣がん 新規治療法の探索 シスプラチン内包CD24高分子ミセルの開発とマウス難治性卵巣癌モデルへの治療検討

  芦原 敬允, 寺井 義人, 前田 和也, 小野 賀大, 中村 起代子, 兪 史夏, 田中 智人, 田中 良道, 林 正美, 田辺 晃子, 金村 昌徳, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2015, 日本産科婦人科学会雑誌, 67(2) (2), 499 - 499, Japanese


• Crosstalk between PI3K and Ras pathways via protein phosphatase 2A in human ovarian clear cell carcinoma

  Masaaki Takai, Takatoshi Nakagawa, Akiko Tanabe, Yoshito Terai, Masahide Ohmichi, Michio Asahi

  Feb. 2015, CANCER BIOLOGY & THERAPY, 16(2) (2), 325 - 335, English

  [Refereed]

  Scientific journal


• Laparoscopic management of torsion of an ovarian cyst with 13kg of tumor liquid

  TSUNETOH Satoshi, TERAI Yoshito, YOO Saha, FUJIWARA Satoe, TANAKA Yoshimichi, TANAKA Tomohito, KANEMURA Masanori, OHMICHI Masahide

  The definition of giant ovarian tumor applies when the total weight of the tumor is 10 to 20 kg (or more), or the weight ratio is 20% or more of body weight. Torsion caused by giant ovarian tumors is quite rare, occurring in only 2.9% of cases. We report a rare case where torsion occurred when the tumor had reached a size of 34 cm and had a liquid content of 13 kg. In this case, the patient was 26-year-old, nonparous, and morbidly obese with a body mass index of 43. She had no previous history. She began to feel pain in her lower abdomen and received a medical examination from another physician three days later. The doctor suspected an unusually large ovarian cyst and referred the patient to our hospital for medical treatment. At the initial visit, the patient's chief complaint was of lower abdominal pain and dyspnea. The suspected tumor was palpable as a large mass up to the hypochondrium, and mild Blumberg sign was seen in the lower left abdomen. Transabdominal ultrasonography revealed a single-wall cystic mass 32 cm in size. At the time, she was emergently hospitalized with the diagnosis of acute abdominal pain and giant ovarian cyst. The only tumor marker which was elevated was CA125 at 41.9 U/ml. A contrast CT examination revealed a mass 34 × 31 × 27 cm in size, and the patient was diagnosed with torsion of the left ovarian tumor due to the loss of contrast effect in that area. Thereafter, the patient underwent an emergency laparoscopic left salpingo-oophorectomy on the same day of hospitalization. The cyst surface was a deep violet-blue, and the left side adnexa was twisted 540 degrees counter-clockwise. The right side adnexa was normal. We used a SAND balloon catheter® to aspirate the intratumoral fluid at a rate of about 500 ml/min. A total of 13590ml of serous fluid was aspirated from the cyst. Although ovarian torsion was released, the color of tumor mass did not return to normal. After the left salpingo-oophorectomy, the cyst was recovered from the right side umbilical port by Endo Catch II®. Ascites fluid cytology revealed no malignant cells, and the intraoperative pathological diagnosis was a serous adenoma. Surgery time was 3 hours and 10 minutes, and intraoperative blood loss was 30g. The patient made an uneventful postoperative recovery and was discharged on the fifth postoperative day. The final pathological diagnosis was serous adenoma. [Adv Obstet Gynecol, 67 (2) : 95-100 , 2015 (H27.5)]

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2015, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 67(2) (2), 95 - 100, Japanese


• Fertility sparing staging laparotomy in early stage ovarian cancer

  KOGATA Yuhei, SASAKI Hiroshi, HASHIDA Sosuke, ASHIHARA Keisuke, MAEDA Kazuya, FUJIWARA Satoe, YOO Saha, TANAKA Tomohito, TANAKA Yoshimichi, TSUNETOH Satoshi, KANEMURA Masanori, TERAI Yoshito, OHMICHI Masahide

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2015, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 67(3) (3), 340 - 343, Japanese


• Endometrioid adenocarcinoma arising from uterine adenomyosis : a report of eight cases

  KONISHI Hiromi, SASAKI Hiroshi, YOO Saha, TANAKA Yoshimichi, TSUNETOH Satoshi, KANEMURA Masanori, TERAI Yoshito, OHMICHI Masahide

  Adenomyosis is defined by the presence of endometrial tissue within the myometrium, and the malignant transformation of adenomyosis in premenopausal women with normal endometrium is extremely rare. We report a case of eight endometrioid adenocarcinoma arising from an adenomyotic focus in the uterus. 497 patients with endometrial cancer were identified, of which eight had tumors arising from uterine adenomyosis. Among the 8 patients, 6 presented at stage IA (75%), 1 at stage IB (12.5%), and 1 at stage IIIC (12.5%). The histological subtype of the eight tumors was endometrioid, with 3 at grade 1 and 5 at grade 2. In all cases, a transition between the carcinomas and the adenomyotic glands was observed. Additionally, there was no difference of in median age (p=0.42) and myometrium invasion (p=0.10) in all cases when compared with normal cases without carcinoma arising from uterine adenomyosis.The accuracy of endometrium biopsy for preoperative diagnosis with hysteroscopy was 75%, and the accuracy of myometrial invasion for preoperative diagnosis with magnetic resonance imaging was 88%. Moreover, the accuracy of intraoperative consultation was 100%. All patients are currently disease-free. Endometrial cancer arising from adenomyosis is rare and difficult to diagnose preoperatively. Although these eight cases resulted in a good prognosis, their number was few. Therefore, we should accumulate more cases of endometrial cancer arising in adenomyosis. [Adv Obstet Gynecol, 67 (3) : 247-253, 2015 (H27.8)]

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2015, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 67(3) (3), 247 - 253, Japanese


• Uterine Intravenous Leiomyomatosis with Cardiac Extension: Radiologic Assessment with Surgical and Pathologic Correlation.

  Nakai G, Maeda K, Yamamoto K, Yamada T, Hirose Y, Terai Y, Ohmichi M, Katsumata T, Narumi Y

  2015, Case reports in obstetrics and gynecology, 2015, 576743

  [Refereed]


• Decorin induced by progesterone plays a crucial role in suppressing endometriosis

  Yoshihiro Joshua Ono, Yoshito Terai, Akiko Tanabe, Atsushi Hayashi, Masami Hayashi, Yoshiki Yamashita, Satoru Kyo, Masahide Ohmichi

  Nov. 2014, JOURNAL OF ENDOCRINOLOGY, 223(2) (2), 203 - 216, English

  [Refereed]

  Scientific journal


• Ovarian estradiol production and lipid metabolism in postmenopausal women.

  Risa Maruoka, Akiko Tanabe, Ayako Watanabe, Kiyoko Nakamura, Keisuke Ashihara, Tomohito Tanaka, Yoshito Terai, Masahide Ohmichi

  OBJECTIVE: Menopause is defined as the permanent cessation of menses. Although previous studies demonstrated a slight production of androgens and estrogens by postmenopausal ovaries, the impact of hormone production on lipid metabolism is still uncertain. The aim of this study was to evaluate whether the postmenopausal ovary is hormonally active and whether hormone status contributes to lipid metabolism. METHODS: This was a prospective study of 87 women who were treated for gynecological diseases (29% had cervical cancer, 49% had endometrial cancer, 7% had fibroid tumors, and 15% had cervical intraepithelial neoplasia). They were categorized as early postmenopausal (n = 40; mean [SD], 56.8 [3.8] y) or late postmenopausal (n = 47; mean [SD], 66.6 [5.7] y) women. Serum specimens were collected from the peripheral and ovarian veins of participants undergoing bilateral oophorectomy. Sex steroid hormone levels and lipid profiles were determined. RESULTS: Statistically significant differences in estradiol (E2) and testosterone were seen between the ovarian samples and the peripheral samples in all groups. E2 and estrone obtained from ovarian venous samples gradually decreased with age in postmenopausal women. There was a significant correlation between ovarian E2 and high-density lipoprotein cholesterol levels and the low-density lipoprotein-to-high-density lipoprotein ratio. However, there was no correlation between peripheral E2 levels and any of the lipid parameters examined. CONCLUSIONS: Although this study investigates women with gynecological diseases, the postmenopausal ovary is hormonally active, and the E2 produced by postmenopausal ovaries may therefore contribute to the maintenance of lipid metabolism.

  Oct. 2014, Menopause (New York, N.Y.), 21(10) (10), 1129 - 35, English, International magazine

  Scientific journal


• 体外受精治療における化学的流産周期の検討

  岡本 敦子, 林 篤史, 中村 真由美, 田吹 邦雄, 劉 昌恵, 小野 賀大, 林 正美, 寺井 義人, 大道 正英

  「産婦人科の進歩」編集室, Oct. 2014, 産婦人科の進歩, 66(4) (4), 490 - 490, Japanese


• Postmenopausal patients with endometrial cancer of type 1 have elevated serum estradiol levels in the ovarian vein.

  Keisuke Ashihara, Tomohito Tanaka, Risa Maruoka, Yoshihiro J Ono, Akiko Tanabe, Yoshito Terai, Masahide Ohmichi

  OBJECTIVE: Type 1 endometrial cancer (EC) is typically sex hormone sensitive; however, most women diagnosed with EC have already gone through menopause. Several studies have reported that the postmenopausal ovary is hormonally active, and estradiol (E2) production from the ovaries persists for as much as 10 years beyond menopause. The aim of this study was to evaluate whether sex steroid production from the ovaries contributes to the pathogenesis of type 1 EC. MATERIALS AND METHODS: This was a prospective study of 53 women treated for EC (28 cases of type 1 disease and 25 cases of type 2 disease). Serum specimens were collected from the peripheral and ovarian veins of participants undergoing bilateral oophorectomy. The sex steroid hormone levels and hormonal milieu on cervical cytology were evaluated as maturation value (MV). In addition, the degree of stromal hyperplasia of the ovary was evaluated histologically. RESULTS: Although the E2 levels of the peripheral veins did not show any significant differences [8.2 (5.1-12.4) vs 7.4 (5.1-11.7) pg/mL, respectively; P < 0.05], the patients with type 1 EC had a higher E2 level in the ovarian vein than those with type 2 EC [25 (13.8-42.5) vs 15 (10.0-23.0) pg/mL, respectively; P < 0.05]. There were also no significant differences in the rate of moderate to marked hyperplasia of the ovarian stroma between the groups; however, the thickness of the ovarian cortex demonstrated a correlation with the ovarian E2 level. In addition, the MV displayed a strong correlation with the ovarian E2 level, but not the peripheral E2 level. CONCLUSIONS: The postmenopausal ovary is hormonally active, especially in patients with type 1 EC. The degree of ovarian stromal hyperplasia may (at least in part) contribute to the progression of type 1 EC, and MV may predict the level of E2 production from the ovaries in postmenopausal women.

  Oct. 2014, International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 24(8) (8), 1455 - 60, English, International magazine

  Scientific journal


• The EMT (epithelial-mesenchymal-transition)-related protein expression indicates the metastatic status and prognosis in patients with ovarian cancer.

  Masaaki Takai, Yoshito Terai, Hiroshi Kawaguchi, Keisuke Ashihara, Satoe Fujiwara, Tomohito Tanaka, Satoshi Tsunetoh, Yoshimichi Tanaka, Hiroshi Sasaki, Masanori Kanemura, Akiko Tanabe, Masahide Ohmichi

  OBJECTIVES: The epithelial-mesenchymal-transition (EMT) is an important step in the invasion and metastasis of cancer. A critical molecular feature of this process is the downregulation of the E-cadherin expression, which is primarily controlled by Snail-related zinc-finger transcription factors. The aim of this study was to evaluate the prognostic impact of the expression of EMT-related proteins (E-cadherin and Snail) in patients with ovarian cancer. METHODS: An immunohistochemical analysis was conducted using tissue microarray samples of 174 primary tumors and 34 metastases of ovarian carcinoma, and the relationships between the protein expression, clinicopathological features and outcomes were investigated. RESULTS: A reduced E-cadherin expression was observed in 36.8% of the primary tumors and 30.4%, 35.7%, 37.7% and 52.7% of the stage I, II, III and IV tumors, respectively. The nuclear expression of Snail was positive in 33.9% of the primary tumors. The rate of an EMT-positive status, as represented by both a reduced E-cadherin expression and a nuclear expression of Snail, was significantly higher in the patients with peritoneal dissemination than in those without (p < 0.05). The EMT status was significantly associated with both the progression-free survival and overall survival (p <0.01). A multivariate analysis showed an EMT-positive status to be a significant predictor of both the progression-free survival (p < 0.05) and overall survival (P < 0.01). CONCLUSIONS: These data indicate that the EMT status is significantly associated with peritoneal metastasis and both the progression-free survival and overall survival in patients with ovarian cancer. Therefore, clarifying and controlling EMT signaling is a promising approach to molecular targeted therapy for ovarian cancer.

  Jul. 2014, Journal of ovarian research, 7, 76 - 76, English, International magazine

  Scientific journal


• Associations between the pre-pregnancy body mass index and gestational weight gain with pregnancy outcomes in Japanese women.

  Tomohito Tanaka, Keisuke Ashihara, Michihiko Nakamura, Takayoshi Kanda, Daisuke Fujita, Yoshiki Yamashita, Yoshito Terai, Hideki Kamegai, Masahide Ohmichi

  AIM: To examine the associations between the pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) with pregnancy outcomes in Japanese women. METHODS: The medical records of 1883 Japanese women who delivered singleton infants from January 2010 to January 2013 at Osaka-Minami Medical Center were retrospectively reviewed. We use the BMI classification which the World Health Organization defined for Asian populations and the GWG classified based on the current 2009 Institute of Medicine (IOM) recommendations. The odds ratio (OR) of each of the groups for the different pregnancy outcomes were compared to the recommended group using a logistic regression analysis adjusted by age, gestational weeks, parity, weight gain, mode of delivery, pregnancy induced hypertension (PIH) and gestational diabetes mellitus. RESULTS: Women who were obese (BMI, ≥25 kg/m(2) ) and overweight (BMI, 23-24.9 kg/m(2) ) had a higher rate of developing PIH (adjusted OR, 6.68 and 3.21 [95% confidence interval [CI], 3.31-13.3 and 1.29-7.24]). In contrast, GWG exhibited a correlation with the weight of the infant. The inadequate GWG group had a higher rate of small-for-gestational age (SGA) infants (adjusted OR, 1.72 [95% CI, 1.22-2.46]). The rate of emergency cesarean section was not significantly different between the groups. CONCLUSION: A pre-pregnancy BMI less than 23 kg/m(2) is desirable to prevent Japanese women from developing PIH. GWG within the IOM recommendations also reduced the risk of PIH and SGA.

  May 2014, The journal of obstetrics and gynaecology research, 40(5) (5), 1296 - 303, English, International magazine

  Scientific journal


• Gemcitabine as a molecular targeting agent that blocks the Akt cascade in platinum-resistant ovarian cancer.

  Hiroshi Kawaguchi, Yoshito Terai, Akiko Tanabe, Hiroshi Sasaki, Masaaki Takai, Satoe Fujiwara, Keisuke Ashihara, Yoshimichi Tanaka, Tomohito Tanaka, Satoshi Tsunetoh, Masanori Kanemura, Masahide Ohmichi

  BACKGROUND: Gemcitabine (2', 2' -difluorodeoxycytidine) is one of many nonplatinum drugs that exhibit activity in recurrent, platinum-resistant ovarian cancer. However, the molecular mechanisms by which Gemcitabine treatment inhibits the proliferation of platinum-resistant ovarian cancer cells still remain unclear. We investigated whether Gemcitabine increases the efficacy of Cisplatin in platinum-resistant ovarian cancer models in vitro and in vivo. METHODS: We used Cisplatin-resistant Caov-3 cells, A2780CP cells and Cisplatin-sensitive A2780 cells to examine the sensitivity of the cell viability of Cisplatin and Gemcitabine using a 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay and the sensitivity of the invasive activity of Cisplatin and Gemcitabine using an invasion assay with Matrigel. We examined the Akt kinase activity and matrix metalloproteinase 9 (MMP9) expression following Cisplatin and Gemcitabine treatment using a Western blot analysis and the mRNA expression of vascular endothelial growth factor (VEGF) using semi-quantitative RT-PCR. Moreover, we evaluated the effects of Cisplatin and Gemcitabine on the intra-abdominal dissemination of ovarian cancer in vivo. RESULTS: Gemcitabine significantly inhibited Cisplatin-induced Akt activation in the Caov-3 and A2780CP cells, but not in the A2780 cells. In the presence of Gemcitabine, Cisplatin-induced growth inhibition and apoptosis were significantly enhanced in the Caov-3 and A2780CP cells. Co-treatment with Cisplatin and Gemcitabine almost completely inhibited invasion of both types of cells through the Matrigel; however, neither Cisplatin nor Gemcitabine alone inhibited the invasion of both types of cells. Gemcitabine inhibited not only the Cisplatin-induced activation of Akt, but also the MMP9 and mRNA expression of VEGF. Moreover, treatment with Gemcitabine increased the efficacy of Cisplatin-induced growth inhibition of the intra-abdominal dissemination and production of ascites in the athymic nude mice inoculated with Caov-3 cells. CONCLUSIONS: We herein demonstrated that Gemcitabine inhibits the Akt kinase activity and angiogenetic activity following treatment with Cisplatin in platinum-resistant ovarian cancer cells. These results provide a rationale for using Gemcitabine in clinical regimens containing molecular targeting agents against platinum-resistant ovarian cancers.

  Apr. 2014, Journal of ovarian research, 7, 38 - 38, English, International magazine

  Scientific journal


• Total laparoscopic modified radical hysterectomy with lymphadenectomy for endometrial cancer compared with laparotomy.

  Yoshito Terai, Tomohito Tanaka, Hiroshi Sasaki, Hiroshi Kawaguchi, Satoe Fujiwara, Saha Yoo, Yoshimichi Tanaka, Satoshi Tsunetoh, Masanori Kanemura, Masahide Ohmichi

  AIM: This is the first report to determine the feasibility and safety of total laparoscopic modified radical hysterectomy (TLMRH) in the treatment of presumed stage I endometrial cancer. METHODS: This was a retrospective study of 132 consecutive patients who underwent surgery for early endometrial cancer. Thirty-nine patients underwent TLMRH and bilateral salpingo-oophorectomy (BSO), and 93 had a total abdominal extrafascial hysterectomy and BSO. Lymphadenectomy was performed in 87 patients. The groups were compared for epidemiological and clinical characteristics, surgical outcomes, hospital stay, lymph nodes harvested, and intraoperative and postoperative complications. RESULTS: The patients in the TLMRH group had less blood loss (42.9 ± 76.3 vs 236.8 ± 186.6 mL, P < 0.0001), a similar number of lymph nodes removed (32.3 ± 13.1 vs 28.0 ± 11.9, P = 0.15), less need for analgesia and a shorter hospital stay (9.3 ± 2.5 vs 14.6 ± 12.6 days, P = 0.009) but longer operations (321.1 ± 65.9 vs 262.6 ± 75.0 min, P < 0.0001) than those treated by laparotomy. In our study, we had no conversions from laparoscopy to laparotomy. No major complications occurred in the TLMRH group. The patients who underwent TLMRH had less intense postoperative pain than patients treated by laparotomy. The median length of vaginal cuff removed was 12.0 ± 4.1 mm in the TLMRH group, and was 5.6 ± 6.6 mm in the laparotomy group (P < 0.0001). No patients demonstrated recurrence in either of the groups after a median follow-up of 48.5 months (range, 1-84). CONCLUSION: TLMRH is a safe and reliable alternative to open surgery in the management of early endometrial carcinoma, with a significantly reduced hospital stay and complications.

  Feb. 2014, The journal of obstetrics and gynaecology research, 40(2) (2), 570 - 5, English, International magazine

  Scientific journal


• A low-testosterone state associated with endometrioma leads to the apoptosis of granulosa cells.

  Yoshihiro J Ono, Akiko Tanabe, Yoko Nakamura, Hikaru Yamamoto, Atsushi Hayashi, Tomohito Tanaka, Hiroshi Sasaki, Masami Hayashi, Yoshito Terai, Masahide Ohmichi

  Although endometriosis is suspected to be a cause of premature ovarian insufficiency (POI), the mechanism(s) underlying this process have not been elucidated. Recently, androgens were shown to promote oocyte maturation and to play a role in folliculogenesis. In addition, several reports have documented low testosterone levels in the follicular fluid obtained from endometriosis patients. We therefore examined whether the low levels of serum testosterone are associated with the apoptosis of granulosa cells in follicles obtained from endometriosis patients. Serum samples were collected from 46 patients with endometriosis and from 62 patients without endometriosis who received assisted reproductive therapy. Specimens of the ovaries obtained from 10 patients with endometrioma were collected using laparoscopy. The mean serum testosterone concentration in the patients with endometriosis was significantly lower than that observed in the patients without endometriosis. Furthermore, high expression of a pro-apoptotic Bcl-2 member, BimEL, in the follicles was found to be associated with a low serum testosterone level. We clarified the underlying mechanisms using a basic approach employing human immortalized granulosa cells derived from a primary human granulosa cell tumor, the COV434 cell line. The in vitro examination demonstrated that testosterone inhibited apoptosis induced by sex steroids depletion via the PI3K/Akt-FoxO3a pathway in the COV434 cells. In conclusion, we elucidated the mechanism underlying the anti-apoptotic effects of testosterone on granulosa cells, and found that a low-testosterone status is a potentially important step in the development of premature ovarian insufficiency in patients with endometriosis.

  2014, PloS one, 9(12) (12), e115618, English, International magazine

  Scientific journal


• Clinicopathologic features of malignant transformation in four patients with ovarian endometrioma

  TABUKI Kunio, TERAI Yoshito, TANAKA Yoshimichi, SASAKI Hiroshi, TSUNETO Keiji, KANAMURA Masanori, OHMICHI Masahide

  Endometriois is a common gynecological disorder, and is seen in about 10% of women. It usually presents patients with complications such as pelvic pain, infertility or adnexal masses. Recently, endometiosis has been identified as a precursor of ovarian cancer, and it has been reported that 0.7% of the patients with ovarian endometrioma have a risk of developing ovarian cancer. The purpose of this study is to describe the clinicopathologic features of malignant transformation in four patients with ovarian endometrioma as well as their treatment and outcome. The mean age at presentation of malignant transformation was 43.3 years (range, 38-48 years). Two of four cases had a more than 10 year period since endometriosis was first diagnosed. However, in one of the four cases, there appeared a sign of malignant transformation within one month after ovarian endometrioma was found. The diameter of ovarian masses ranged from 8 cm to 20 cm. The preoperative CA125 level was 56.9~313 U/ml, and the CA19-9 level was 99~174 U/ml respectively. On the basis of MRI images, the appearance of contrast-enhanced mural nodules which were low signal in T2-weighted images were detected. T1-weighted MR images showed the cystic mass with iso-low signal intensity, and T2-weighted MR images showed high signal intensity. Optimal surgery for ovarian cancer was performed in all cases. The histological subtypes were two endometrioid adenocarcinomas and two clear cell adenocarcinomas. The FIGO stages were 1A, 1C, 2C and 3C respectively. Adjuvant chemotherapy was added in three cases. None of the patients experienced disease progression nor died of the disease. The appearance of contrast-enhanced mural nodules is the most important finding for the diagnosis of malignant transformation of endometrioma on the basis of MR imaging. Moreover, enlargement of the endometrioma with the disappearance of shading on T2-weighted images is suggestive of malignant transformation. We experienced a case in which mural nodules appeared in the short term (within one month) after endometrioma was found and another case in which advanced ovarian cancer was discovered even though the patient had taken an annual MRI. In the case of large endometriotic cysts around menopausal age, the risk of malignant transformation increases. Therefore, the management of endometriosis from the standpoint of endometriosis associated ovarian cancer is important. Clinicians should be aware of the increased risk of ovarian cancer in woman with endometriosis. [Adv Obstet Gynecol, 66 (2):155-162, 2014 (H26.5)]

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2014, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 66(2) (2), 155 - 162, Japanese


• Role of the two-point pull-up technique for treating the uterine arteries during radical hysterectomy and trachelectomy.

  Saha Yoo, Yoshito Terai, Tomohito Tanaka, Yoshimichi Tanaka, Satoshi Tsunetoh, Masanori Kanemura, Masahide Ohmichi

  OBJECTIVES: To introduce a safe and reliable method for the management of peripheral vessels around the uterine artery during abdominal radical hysterectomy or abdominal radical trachelectomy. STUDY DESIGN: From 2007 to 2011, 102 patients with invasive cervical cancer underwent an abdominal radical hysterectomy. In 48 operations in 2007-2009, we performed the conventional radical hysterectomy, in which we ligated and cut the uterine arteries at their origin, and we divided the anterior leaf of the vesico-uterine ligament by blindly inserting scissors into the ureteral tunnel, pushing the ureter laterally from the cervix. In 54 operations in 2009-2011, we pulled up the origin and the bifurcation of the uterine artery using vessel tape, skeletonized the uterine artery and directly divided the superficial uterine vein, superior vesical vein and ureteric branch of the uterine artery. We also performed four radical trachelectomies using the two point pull-up method. We investigated whether this method was useful for the management of peripheral vessels around the uterine artery. RESULTS: The mean total blood loss in the two point pull-up method group (485 ± 270 ml) was significantly lower than that in the conventional surgery group (686 ± 554 ml) (p<0.05). The mean length of the operation in the two point pull-up method group (481 ± 53 min) was not significantly different from the conventional surgery group (497 ± 74 min) (p=0.111). The mean number of dissected lymph nodes in the two point pull-up method group (37.2 ± 11.6) was not significantly different from that in the conventional method group (34.4 ± 10.2) (p=0.096). The overall survival and progression-free survival were also not substantially different between the two groups. In the radical trachelectomy, the mean blood loss was 377.5 ± 185.6 ml and the mean duration of surgery was 520.0 ± 48.5 min using the two point pull-up method. We were able to preserve both uterine arteries without accidental injury or disruptive bleeding. All four patients were menstruating normally as of the last examination. CONCLUSIONS: The two point pull-up method enabled us to reduce intraoperative blood loss without increasing other complications during abdominal radical hysterectomy or abdominal radical trachelectomy.

  Oct. 2013, European journal of obstetrics, gynecology, and reproductive biology, 170(2) (2), 544 - 9, English, International magazine

  Scientific journal


• Comparison of the perinatal outcomes after laparoscopic myomectomy versus abdominal myomectomy.

  Mamiko Fukuda, Tomohito Tanaka, Mika Kamada, Atsushi Hayashi, Yoshiki Yamashita, Yoshito Terai, Masahide Ohmichi

  BACKGROUND/AIMS: To compare the perinatal outcomes after laparoscopic myomectomy (LM) versus abdominal myomectomy (AM). METHODS: The medical records of 105 Japanese females who delivered after myomectomy from 2004 to 2012 at Osaka Medical College were reviewed retrospectively. RESULTS: Of the 105 females who delivered after myomectomy, 48 had undergone LM and 57 had undergone AM. There were no significant differences in the perinatal outcomes including the rates of emergency cesarean sections, preterm deliveries, placental abnormalities, pregnancy-induced hypertension, low Apgar score, non-reassuring fetal heart rate patterns, and intrauterine fetal death. No significant difference was observed in the incidence of post-partum hemorrhage. There was no uterine rupture in either group. 15 (31%) of the females who had LM were candidates for transvaginal delivery, and 14 delivered vaginally (93% success rate). In contrast, 20 (35%) of the females who had AM were candidates for transvaginal delivery, and 19 delivered vaginally (95% success rate). CONCLUSION: There were no significant differences in the perinatal outcomes between the females who had LM and AM. Moreover, both groups had a high rate of successful transvaginal delivery after selecting the appropriate candidates.

  2013, Gynecologic and obstetric investigation, 76(4) (4), 203 - 8, English, International magazine

  Scientific journal


• Laparoscopic diagnosis of adenocarcinoma of the appendix mimicking serous papillary adenocarcinoma of the peritoneum.

  Mayumi Yoshimura, Yoshito Terai, Hiromi Konishi, Yoshimichi Tanaka, Tomohito Tanaka, Hiroshi Sasaki, Masahide Ohmichi

  Primary carcinoma of the vermiform appendix is a rare disease with few clinical symptoms. Accordingly, preoperative diagnosis of appendiceal cancer is challenging because of the lack of specific symptoms. We herein report a case of appendicular adenocarcinoma found unexpectedly during laparoscopic surgery in a 69-year-old Japanese female patient diagnosed with serous papillary adenocarcinoma, in order to determine whether optimal cytoreduction could successfully be achieved at the time of primary surgery. We performed diagnostic laparoscopic surgery in order to make a correct diagnosis based on the histological tissue. The vermiform appendix was found to contain a tumor measuring 1.5 cm wide and 4.5 cm long. Laparoscopic appendectomy, partial omentectomy, and partial resection of the lesion in the peritoneum were performed. The histological diagnosis was mucinous adenocarcinoma of the vermiform appendix, and the stage was T4NxM1. The patient received adjuvant chemotherapy with mFOLFOX 6 (5FU, leucovorin, and oxaliplatin). She achieved stable disease and was alive with disease eleven months after surgery. We therefore recommend that gynecologists should not rule out the possibility of appendiceal cancer, even in cases with preoperative findings similar to those of serous papillary adenocarcinoma of the peritoneum with peritoneal disseminated tumors.

  2013, Case reports in obstetrics and gynecology, 2013, 248917 - 248917, English, International magazine

  Scientific journal


• The usefulness of laparoscopic surgery in diagnosis of advanced ovarian cancer before NAC (neo-adjuvant-chemotherapy)

  TANAKA Yoshimichi, TERAI Yoshito, TERADA Shinichi, KONISHI Hiromi, MARUOKA Hiroshi, SAITO Natsuho, FUKUDA Mamiko, KAWAGUCHI Hiroshi, HIGA Ryoko, NAKAMURA Michihiko, TAKAI Masaaki, FUJIWARA Satoe, YOO Saha, TANAKA Tomohito, TSUNETO Satoshi, KANEMURA Masanori, OHMICHI Masahide

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2013, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 65(4) (4), 461 - 464, Japanese


• GPR30 regulates the EGFR-Akt cascade and predicts lower survival in patients with ovarian cancer.

  Satoe Fujiwara, Yoshito Terai, Hiroshi Kawaguchi, Masaaki Takai, Saha Yoo, Yoshimichi Tanaka, Tomohito Tanaka, Satoshi Tsunetoh, Hiroshi Sasaki, Masanori Kanemura, Akiko Tanabe, Yoshiki Yamashita, Masahide Ohmichi

  OBJECTIVES: G protein-coupled receptor 30 (GPR30) is a 7-transmembrane estrogen receptor that functions alongside traditional estrogen receptors to regulate the cellular responses to estrogen. Recent studies suggest that GPR30 expression is associated with a poor prognosis, and that this is due to the GPR30-mediated transactivation of the EGFR in breast cancer. However, the biological contribution of GPR30 in ovarian cancer remains unclear. The purpose of this study was to elucidate the relationships between GPR30 expression and the clinicopathological findings, and to determine how the signaling cascade influences the prognosis of ovarian cancer. METHODS: The expression levels of GPR30, EGFR, ERα, and ERβ were analyzed using an immunohistochemical analysis, and their correlations with the clinicopathological features were examined in 10 patients with borderline malignant tumors and 152 patients with epithelial ovarian cancer. We also examined whether GPR30 signaling activates the EGFR-Akt pathway in an ovarian cancer cell line (Caov-3) by a Western blotting analysis. RESULTS: The GPR30 expression in ovarian carcinomas was significantly higher than that in borderline malignancies (p=0.0016), and was not associated with the expression of the EGFR, ERα, or ERβ. The expression of GPR30 in clear cell carcinomas was significantly lower than that in other subtypes of cancer (P <; 0.001). The expression of both GPR30 and EGFR was significantly associated with a poor prognosis in terms of the progression-free survival rate. The phosphorylation of the EGFR and Akt could be significantly enhanced by G1 (p <; 0.05) and inhibited by a Src family kinase inhibitor. CONCLUSION: The expression of both GPR30 and EGFR is associated with a poor outcome in ovarian cancer, and GPR30 increases the phosphorylation of Akt via the EGFR in ovarian cancer cells. The regulation of GPR30 might be a potentially useful new therapeutic target in ovarian cancer.

  Nov. 2012, Journal of ovarian research, 5(1) (1), 35 - 35, English, International magazine

  Scientific journal


• Analysis of the correlation between systematic lymphadenectomy and myometrial invasion in endometrial cancer

  FUJIWARA Satoe, TAKAI Masaaki, YU Saha, TANAKA Yoshimichi, TSUNETOH Satoshi, SASAKI Hiroshi, KANEMURA Masanori, TERAI Yoshito, OHMICHI Masahide

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2012, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 64(3) (3), 364 - 366, Japanese


• Successful long-term dienogest therapy for recurring pelvic pain due to endometriosis after laparoscopic surgery : a case report

  KUMAGAI Koji, OKUDA Kiyoji, TERAI Yoshito, YASUDA Masayuki, YAMASHITA Yoshiki, OHMICHI Masahide

  We report the case of successful long-term dienogest therapy for recurring pelvic pain due to endometriosis after laparoscopic surgery. A 38-year-old woman (46 years old at present; 2 gravida, 1 para) presented to our hospital with severe pelvic pain that persisted both during and around her menstrual period. Herbal medicines or oral contraceptives that were administered for 1 year partially reduced the pain. The patient underwent laparoscopic surgery for complete relief from the pain. Laparoscopic observation confirmed stage IV endometriosis, which was evaluated according to the revised American Society for Reproductive Medicine (r-ASRM) classification system. We dissected both the severe adnexal adhesions, excised both ovarian chocolate cysts, and dissected extensive adhesion in the cul-de-sac. After the surgery, the patient was prescribed oral contraceptives for 2 years as maintenance therapy. However, the pain recurred; hence, she was treated with oral dienogest (2 mg/day) for 56 weeks. 22 weeks after drug cessation, she was again treated with the same dose for the next 81 weeks, until presently. Almost complete relief from the pain was achieved using this long-term dienogest therapy. No obvious side effects adverse events were observed, except for dizziness and scant uterine bleeding. The present case indicates that long-term dienogest therapy (lasting even over 80 weeks) after laparoscopic surgery is effective and safe. Dienogest therapy may be a novel alternative post-laparoscopic treatment for pelvic pain due to endometriosis. [Adv Obstet Gynecol, 64(1) : 41-48, 2012 (H24.2)]

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2012, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 64(1) (1), 41 - 48, Japanese


• Interstitial pregnancy treated by transcervical aspiration of the gestational sac combined with systemic and local administration of methotrexate.

  Sousuke Kato, Tomohito Tanaka, Yoshito Terai, Yoshiki Yamashita, Masahide Ohmichi

  Interstitial pregnancy, which is a rare form of tubal ectopic pregnancy, can grow larger than those within the fallopian tube because the surrounding myometrium is more expandable than the tube; many cases are advanced and treated with surgical resection or a large amount of methotrexate (MTX). This report presents a case of an advanced interstitial pregnancy treated with systemic MTX and laparoscopic local MTX injection combined with transcervical aspiration of the gestational sac. A 27-year-old nulliparous female presented with an interstitial pregnancy. Serum human chorionic gonadotropin (hCG) level was 90000 IU/L. MTX was given systemically (50 mg/m(2) i.m.) and the gestational sac was aspirated transcervically under laparoscopic guidance followed by local injection of 25 mg MTX. The patient received a total of only 95 mg MTX. The gestational sac disappeared and serum hCG became undetectable. The patient became pregnant spontaneously six months later, and delivered a live 2482-g infant in good condition by planned cesarean section at 36 weeks and 3 days of gestation. No defect of the myometrium was seen during the surgery. This therapy may be effective for interstitial pregnancy and can be performed safely with laparoscopy.

  Sep. 2011, The journal of obstetrics and gynaecology research, 37(9) (9), 1250 - 4, English, International magazine

  Scientific journal


• 子宮体癌における筋層浸潤の予後への影響とリンパ節郭清の意義

  藤原 聡枝, 原田 洋子, 広田 千賀, 田吹 邦雄, 小西 博巳, 植木 絢子, 古形 祐平, 多賀 紗也香, 川口 浩史, 兪 史夏, 田中 良道, 関島 龍治, 恒遠 啓示, 佐々木 浩, 金村 昌徳, 寺井 義人, 大道 正英

  (公社)日本婦人科腫瘍学会, Jun. 2011, 日本婦人科腫瘍学会雑誌, 29(3) (3), 583 - 583, Japanese


• 当院で経験した境界悪性傍卵巣腫瘍の2例

  澤田 雅美, 林 美佳, 吉村 真由美, 多賀 紗也香, 広田 千賀, 川口 浩史, 藤原 聡枝, 兪 史夏, 田中 良道, 関島 龍治, 恒遠 啓示, 佐々木 浩, 金村 昌徳, 寺井 義人, 大道 正英

  「産婦人科の進歩」編集室, May 2011, 産婦人科の進歩, 63(2) (2), 241 - 241, Japanese


• Outcome of neoadjuvant chemotherapy for advanced uterine cervical cancer

  KAWAGUCHI Hiroshi, KANEMURA Masanori, ASHIHARA Keisuke, YU Masae, MAEDA Kazuya, NISHIO Keina, FUJIWARA Satoe, YU Saha, TANAKA Yoshimichi, SEKIJIMA Tatsuharu, TSUNETOH Satoshi, SASAKI Hiroshi, TERAI Yoshito, OHMICHI Masahide

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2011, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 63(3) (3), 356 - 358, Japanese


• Vascular Endothelial Growth Factor Is a Promising Therapeutic Target for the Treatment of Clear Cell Carcinoma of the Ovary

  Seiji Mabuchi, Chiaki Kawase, Deborah A. Altomare, Kenichirou Morishige, Masami Hayashi, Kenjiro Sawada, Kimihiko Ito, Yoshito Terai, Yukihiro Nishio, Andres J. Klein-Szanto, Robert A. Burger, Masahide Ohmichi, Joseph R. Testa, Tadashi Kimura

  Aug. 2010, MOLECULAR CANCER THERAPEUTICS, 9(8) (8), 2411 - 2422, English

  Scientific journal


• Outcome of mucinous epithelial ovarian cancer

  SASAKI Hiroshi, SEKIJIMA Ryuji, TANAKA Yoshimichi, TSUNETOH Keiji, KANEMURA Masanori, TERAI Yoshito, OHMICHI Masahide

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2010, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 62(1) (1), 32 - 34, Japanese


• The study of the significance of PET-CT for the diagnosis of gynecologic cancer

  TSUNETOH Satoshi, TERAI Yoshito, FUJIWARA Satoe, TANAKA Yoshimichi, SEKIJIMA Tatsuharu, SASAKI Hiroshi, KANEMURA Masanori, OHMICHI Masahide

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2010, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 62(3) (3), 255 - 257, Japanese


• Outcome of recurrent epithelial ovarian cancer

  TANAKA Yoshimichi, SEKIJIMA Tatsuharu, TSUNETOH Keiji, SASAKI Hiroshi, TAKEHARA Mikio, KANEMURA Masanori, TERAI Yoshito, OHMICHI Masahide

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2009, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 61(1) (1), 17 - 20, Japanese


• Para-aortic lymphadenectomy for gynecologic cancers

  TERAI Yoshito

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2009, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 61(1) (1), 61 - 64, Japanese


• The outpatient chemotherapy room introduction in our hospital

  TERAI Yoshito, SASAKI Hiroshi, TSUNETOH Satoshi, TANAKA Yoshimichi, TANABE Akiko, TAKEHARA Mikio, KANEMURA Masanori, OHMICHI Masahide

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2008, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 60(2) (2), 105 - 107, Japanese


• A study of conservative therapy with MPA to endometrial cancer and atypical endometrial hyperplasia

  YASUDA Masayuki, INOKI Chiharu, TANAKA Yoshimichi, TSUNETOH Satoshi, SASAKI Hiroshi, TAKEHARA Mikio, KANEMURA Masanori, TERAI Yoshito, OHMICHI Masahide

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2007, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 59(4) (4), 287 - 289, Japanese


• Cervical conization in pregnant woman

  TANAKA Yoshimichi, TSUNETO Keiji, NISHIYAMA Koji, YAMAGUCHI Hiroyuki, IZUMA Shinji, KANEMURA Masanori, YAMASHITA Yoshiki, TERAI Yoshito, KAMEGAI Hideki, OHMICHI Masahide

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2007, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 59(2) (2), 153 - 155, Japanese


• A case report of ovarian clear cell adenocarcinoma associated with atypical endometriosis

  TSUNETO Satoshi, TAKEHARA Mikio, KASAMATSU Mayumi, AKISE Daisuke, TERAI Yoshito, UEDA Masatsugu, TSUJI Motomu, OHMICHI Masahide

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2007, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 59(1) (1), 20 - 22, Japanese


• Clinicopathological analysis of cervical intraepitherial lesion in young women

  NISHIYAMA Koji, KANEMURA Masanori, TANAKA Yoshimichi, YAMAGUCHI Hiroyuki, DEBA Shinji, TSUNETO Keiji, YASUDA Katsuyuki, TAKEHARA Mikio, TERAI Yoshito, OHMICHI Masahide

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2007, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 59(2) (2), 92 - 94, Japanese


• 2 cases of recurrent ovarian borderline tumor after conservative treatment

  TANAKA Tomohito, TERAI Yoshito, YAMAGUCHI Hiroyuki, NISHIYAMA Koji, KANEMURA Masanori, OHMICHI Masahide

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2006, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 58(4) (4), 388 - 392, Japanese


• A case of glassy cell carcinoma of the uterine cervix effectively responding to multimodal therapy

  YASUDA Masayuki, UEDA Masatsugu, TERAI Yoshito, KANEMURA Masanori, NISHIYAMA Koji, TSUNETOH Satoshi, OHMICHI Masahide

  Glassy cell carcinoma (GCC) of the uterine cervix is a rare tumor, accounting for only 1-2% of all cervical carcinomas, and is characterized as an aggressive histologic subtype with poor prognosis. Here we report a case of cervical GCC effectively responding to preoperative intra-arterial infusion chemotherapy (IAC) and postoperative concurrent chemoradiation therapy (CCRT). A 37-year-old woman visited a previous doctor with a complaint of abnormal genital bleeding, was suspected of having cervical carcinoma and referred to our clinic. She was diagnosed with stage IIIb cervical GCC by cytology, colposcopy, biopsy, MRI and rectal examination. The patient received 2 courses of IAC (CDDP:100mg + MMC:20mg + THP:20mg + 5-FU:500mg) and underwent radical surgery after down-staging of the tumor. Postoperatively, she further received CCRT with 3 courses of systemic chemotherapy (CDDP: 20mg + 5-FU: 300mg 5 days) and 50.4 Gy irradiation of the whole pelvis. She has had no recurrent disease for 4 years after treatment. Preoperative IAC and postoperative CCRT may be effective for GCC of the uterine cervix.[Adv Obstet Gynecol, 58(4) : 351-355, 2006 (H18.11)]
  

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2006, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 58(4) (4), 351 - 355, Japanese


• Recurrent ovarian cancer : analysis of treatment outcomes

  AKISE Daisuke, TERAI Yoshito, HIRAI Ryuji, YAMAGUCHI Hiroyuki, UEDA Masatsugu, UEKI Minoru

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2004, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 56(3) (3), 318 - 321, Japanese


• 難治性卵巣癌に対する取り組み

  竹内 聡, 宮本 岳雄, 左右田 裕生, 鈴木 美奈子, 山辺 晋吾, 寺井 義人, 植田 正嗣, 植木 實, 濱名 伸也, 本山 覚, 丸尾 猛

  近畿産科婦人科学会, 2004, 産婦人科の進歩, 56(3) (3), 310 - 310, Japanese


• Neo-adjuvant chemotherapy (balloon occluded arterial infusion)for advanced uterine cervical adenocarcinoma

  UKEI Ken, YAMAGUCHI Hiroyuki, KANDA Koji, TERAI Yoshito, KUMAGAI Koji, UEDA Masatsugu, UEKI Minoru

  THE OBSTETRICAL GYNECOLOGICAL SOCIETY OF KINKI DISTRICT JAPAN, 2003, ADVANCES IN OBSTETRICS AND GYNECOLOGY, 55(1) (1), 33 - 35, Japanese

• 非認証機関でのNIPTで47,XXYもしくは47,XYYの可能性が指摘され、羊水染色体検査で正常核型の診断となった1例

  益子 尚久, 花房 宏昭, 濱 真奈美, 田中 敬子, 前田 美亜, 冨本 雅子, 今福 仁美, 粟野 宏之, 出口 雅士, 寺井 義人, 野津 寛大

  (一社)日本遺伝カウンセリング学会, Jun. 2023, 日本遺伝カウンセリング学会誌, 44(2) (2), 156 - 156, Japanese


• 胎児発育不全児の予後不良に関連する因子の検討

  吉本 梓希子, 谷村 憲司, 久保田 いろは, 栖田 園子, 施 裕徳, 内田 明子, 白川 得朗, 今福 仁美, 出口 雅士, 寺井 義人

  「産婦人科の進歩」編集室, Oct. 2021, 産婦人科の進歩, 73(4) (4), 500 - 500, Japanese


• 非初感染母体から出生した重篤な症候性先天性サイトメガロウイルス感染症児の一例

  今福 仁美, 谷村 憲司, 益子 尚久, 内田 明子, 藤本 将史, 京野 由紀, 藤岡 一路, 出口 雅士, 寺井 義人

  (一社)日本周産期・新生児医学会, Jun. 2021, 日本周産期・新生児医学会雑誌, 57(Suppl.) (Suppl.), P163 - P163, Japanese


• 胎児治療と新生児治療の併用は先天性サイトメガロウイルス感染症児の予後を改善する

  谷村 憲司, 施 裕徳, 内田 明子, 今福 仁美, 藤岡 一路, 森岡 一朗, 出口 雅士, 峰松 俊夫, 寺井 義人, 山田 秀人

  (一社)日本周産期・新生児医学会, Jun. 2021, 日本周産期・新生児医学会雑誌, 57(Suppl.) (Suppl.), P177 - P177, Japanese


• 当院における子宮頸癌に対するベバシズマブの使用経験

  長又 哲史, 清水 真帆, 高橋 良輔, 松本 培世, 村田 友香, 鈴木 嘉穂, 出口 雅士, 寺井 義人

  「産婦人科の進歩」編集室, Oct. 2019, 産婦人科の進歩, 71(4) (4), 419 - 419, Japanese


• 【迫り来る2020:新規保険収載へのロードマップと適正運用】外保連 腹腔鏡下傍大動脈リンパ節郭清術

  寺井 義人

  金原出版(株), Oct. 2019, 産婦人科の実際, 68(11) (11), 1359 - 1364, Japanese


• 当院での腹腔鏡下・ロボット支援下広汎子宮全摘術と開腹広汎子宮全摘術の比較検討

  寺田 信一, 寺井 義人, 宮本 瞬輔, 丸岡 寛, 古形 祐平, 藤原 聡枝, 田中 良道, 田中 智人, 恒遠 啓示, 佐々木 浩, 大道 正英

  (株)メジカルビュー社, Aug. 2019, 産婦人科手術, (30) (30), 162 - 162, Japanese


• 当院における腹腔鏡下子宮体癌手術の治療成績

  藤原 聡枝, 寺井 義人, 寺田 信一, 古形 祐平, 田中 良道, 田中 智人, 佐々木 浩, 恒遠 啓示, 大道 正英

  (株)メジカルビュー社, Aug. 2019, 産婦人科手術, (30) (30), 167 - 167, Japanese


• 卵巣癌初回治療におけるdose-dense TC療法とTC+bevacizumab併用療法の比較

  鈴木 嘉穂, 中筋 由紀子, 安積 麻帆, 高橋 良輔, 長又 哲史, 松本 培世, 出口 雅士, 蝦名 康彦, 寺井 義人

  (公社)日本婦人科腫瘍学会, Jun. 2019, 日本婦人科腫瘍学会雑誌, 37(3) (3), 451 - 451, Japanese


• 卵巣癌・腹膜癌の術前化学療法時の診断において、腹腔鏡下生検と体腔液Cell block法の比較検討

  高橋 良輔, 鈴木 嘉穂, 中筋 由紀子, 安積 麻帆, 長又 哲史, 松本 培世, 出口 雅士, 蝦名 康彦, 寺井 義人

  (公社)日本婦人科腫瘍学会, Jun. 2019, 日本婦人科腫瘍学会雑誌, 37(3) (3), 457 - 457, Japanese


• 子宮頸がんに対する放射線治療後不全骨折発症のリスクについての検討

  松本 培世, 鈴木 嘉穂, 安積 麻帆, 中筋 由紀子, 清水 真帆, 高橋 良輔, 長又 哲史, 蝦名 康彦, 出口 雅士, 寺井 義人

  (公社)日本婦人科腫瘍学会, Jun. 2019, 日本婦人科腫瘍学会雑誌, 37(3) (3), 476 - 476, Japanese


• トラベクテジンの長期投与が可能であった平滑筋肉腫の二例

  長又 哲史, 蝦名 康彦, 安積 麻帆, 高橋 良輔, 松本 培世, 鈴木 嘉穂, 出口 雅士, 寺井 義人

  (公社)日本婦人科腫瘍学会, Jun. 2019, 日本婦人科腫瘍学会雑誌, 37(3) (3), 525 - 525, Japanese


• 妊孕性温存手術を施行したI期の卵巣上皮性境界悪性腫瘍の予後に関する検討

  安積 麻帆, 鈴木 嘉穂, 中筋 由紀子, 高橋 良輔, 松本 培世, 長又 哲史, 出口 雅士, 寺井 義人, 山田 秀人

  (公社)日本婦人科腫瘍学会, Jun. 2019, 日本婦人科腫瘍学会雑誌, 37(3) (3), 530 - 530, Japanese


• 当院で経験した腹膜原発癌肉腫の2例

  中筋 由紀子, 鈴木 嘉穂, 長又 哲史, 安積 麻帆, 高橋 良輔, 松本 培世, 蝦名 康彦, 出口 雅士, 寺井 義人, 山田 秀人

  「産婦人科の進歩」編集室, May 2019, 産婦人科の進歩, 71(2) (2), 230 - 230, Japanese


• Laparoscopic surgery for boderline ovarian tumor during pregnancy: two case reports

  寺田信一, 恒遠啓示, 宮本瞬輔, 古形祐平, 田中良道, 田中智人, 寺井義人, 大道正英

  2019, 産婦人科の進歩, 71(1) (1)


• 子宮体がんにおける腹腔鏡下傍大動脈リンパ節郭清

  寺井義人, 田中智人, 大道正英

  2019, 臨床婦人科産科, 73(12) (12)


• 上皮性卵巣境界悪性腫瘍および卵巣癌118例におけるFDG-PET/CTのSUV max値の検討

  上田尚子, 田中智人, 大瀧瑠璃, 寺田信一, 丸岡寛, 藤原聡枝, 田中良道, 恒遠啓示, 寺井義人, 大道正英

  2019, 日本産科婦人科学会雑誌, 71


• プラチナ感受性再発卵巣癌に対するベバシズマブの有用性

  藤原聡枝, 宮本瞬輔, 丸岡寛, 上田尚子, 田中智人, 田中良道, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2019, 日本産科婦人科学会雑誌, 71


• 子宮頸癌における18F-FDG PET/CTの有用性

  大瀧瑠璃, 寺田信一, 上田尚子, 丸岡寛, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2019, 日本産科婦人科学会雑誌, 71


• 当院での腹腔鏡下広汎子宮全摘出術と開腹広汎子宮全摘出術の排尿障害の検討

  寺田信一, 寺井義人, 宮本瞬輔, 古形祐平, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 山田隆司, 大道正英

  2019, 日本産科婦人科学会雑誌, 71


• 子宮内膜癌・子宮内膜異型増殖症に対するMPA療法の再投与について

  田中良道, 古形祐平, 丸岡寛, 小西博巳, 穀内香奈, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2019, 日本産科婦人科学会雑誌, 71


• 【外科解剖学から解き明かす広汎子宮全摘出術】 子宮がんにおけるセンチネルリンパ節

  田中智人

  Dec. 2018, 産婦人科の実際, 67(13号) (13号), 1735 - 1739, Japanese

  Introduction commerce magazine


• 【妊婦のやせ・肥満 保健指導と分娩管理 リスクと予防法をエビデンスで解説】 やせ・肥満妊婦の分娩管理のポイント 現場で安心してお産に臨むには

  藤田太輔, 大道正英

  Oct. 2018, ペリネイタルケア, 37(10号) (10号), 949 - 951, Japanese

  [Invited]

  Introduction commerce magazine


• 【On Fleek 産婦人科手術】低侵襲手術 悪性 腹腔鏡下骨盤リンパ節郭清手術

  寺田信一, 丸岡寛, 古形祐平, 藤原聡枝, 田中智人, 田中良道, 大道正英

  Oct. 2018, 産婦人科の実際, 67(11号) (11号), 1330 - 1337, Japanese

  [Invited]

  Introduction commerce magazine


• 当院におけるMPA療法後の不妊治療についての検討

  小西 博巳, 林 正美, 田中 サキ, 穀内 香奈, 多賀 紗也香, 寺井 義人, 大道 正英

  (一社)日本生殖医学会, Aug. 2018, 日本生殖医学会雑誌, 63(3) (3), 397 - 397, Japanese


• 【婦人科がん-研究・臨床の新展開】 子宮体癌 子宮体癌 手術療法のあらたな展開

  寺井義人

  Jul. 2018, 医学のあゆみ, 266(1号) (1号), 57 - 62, Japanese

  [Invited]

  Introduction commerce magazine


• 【産科・婦人科の手術看護パーフェクトマニュアル】(第2章)実践編 術式別の術中看護マニュアル 広汎子宮全摘出術(腹腔鏡)

  田中智人

  May 2018, オペナーシング, (2018臨時増刊) (2018臨時増刊), 181 - 191, Japanese

  [Invited]

  Introduction commerce magazine


• 【今、話題になっていること-婦人科編】 婦人科悪性腫瘍に対する鏡視下手術

  寺井義人

  May 2018, 日本医事新報, (4906号) (4906号), 31 - 33, Japanese

  [Invited]

  Introduction commerce magazine


• 臨床経験 45歳以上の超高齢妊娠における周産期予後についての検討

  永昜洋子, 藤田太輔, 大門篤史, 布出実紗, 岡本敦子, 佐野匠, 鈴木裕介, 大道正英

  Mar. 2018, 産婦人科の実際, 67(3号) (3号), 335 - 340, Japanese

  [Refereed]

  Introduction commerce magazine


• 【婦人科がん(第2版)-最新の研究動向-】 子宮体がん 子宮体癌の治療 腹腔鏡下手術(傍大動脈リンパ節郭清を含めて)

  田中智人, 大道正英

  Mar. 2018, 日本臨床, 76(増刊2 婦人科がん) (増刊2 婦人科がん), 429 - 436, Japanese

  [Invited]

  Introduction scientific journal


• 【エキスパートの内視鏡手術-コツとピットフォールI】 子宮体がん 腹腔鏡下子宮体がん手術

  田中良道, 寺田信一, 古形祐平, 芦原敬允, 藤原聡枝, 田中智人, 恒遠啓示, 大道正英

  Mar. 2018, 産婦人科の実際, 67(3号) (3号), 275 - 280, Japanese

  [Refereed][Invited]

  Introduction commerce magazine


• 妊娠高血圧腎症妊婦における血管内皮機能異常と治療による改善効果の検討

  岡本 敦子, 藤田 太輔, 越田 裕一郎, 大門 篤史, 布出 実紗, 永昜 洋子, 中村 真由美, 佐野 匠, 鈴木 裕介, 林 正美, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2018, 日本産科婦人科学会雑誌, 70(2) (2), 808 - 808, Japanese


• 当院におけるMPA療法後の妊娠についての検討

  小西 博巳, 林 正美, 飯藤 宰士, 大瀧 瑠璃, 越田 裕一郎, 土橋 裕允, 穀内 香奈, 中村 奈津穂, 岡本 敦子, 中村 真由美, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2018, 日本産科婦人科学会雑誌, 70(2) (2), 940 - 940, Japanese


• 卵巣境界悪性腫瘍・悪性腫瘍合併妊娠に対する腹腔鏡下手術の検討

  寺田信一, 越田裕一郎, 大門篤史, 布出実紗, 小西博巳, 中村奈津穂, 芦原敬允, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2018, 日本産科婦人科学会雑誌, 70(2) (2)


• 高齢婦人科癌患者に対するweekly TC療法の安全性の検討

  藤原聡枝, 橋田宗祐, 芦原敬允, 古形祐平, 兪史夏, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, 寺井義人, 大道正英

  2018, 日本産科婦人科学会雑誌, 70(2) (2)


• 進行・再発子宮頸癌におけるBevacizumab併用療法の有用性について

  芦原敬允, 飯藤宰士, 橋田宗祐, 寺田信一, 丸岡寛, 古形祐平, 前田和也, 藤原聡枝, 田中智人, 恒遠啓示, 寺井義人, 大道正英

  2018, 日本産科婦人科学会雑誌, 70(2) (2)


• 中隔子宮を伴う不育症に対する子宮鏡下子宮中隔切除術の検討

  前田和也, 藤田太輔, 橋田宗祐, 寺田信一, 丸岡寛, 芦原敬允, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2018, 日本産科婦人科学会雑誌, 70(2) (2)


• 子宮体癌の骨盤リンパ節転移の予測においてのPET-CTとセンチネルリンパ節生検の有用性の比較

  橋田宗祐, 田中智人, 大瀧瑠璃, 丸岡寛, 古形祐平, 前田和也, 芦原敬允, 兪史夏, 藤原聡枝, 佐々木浩, 寺井義人, 大道正英

  2018, 日本産科婦人科学会雑誌, 70(2) (2)


• 70歳以上の高齢者における腹腔鏡下手術の安全性の検討

  丸岡寛, 藤原聡枝, 寺田信一, 中村奈津穂, 古形祐平, 前田和也, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, 寺井義人, 大道正英

  2018, 日本産科婦人科学会雑誌, 70(2) (2)


• 早期子宮頸癌患者に対するリンパ節転移の診断には,FDG PET/CTとセンチネルリンパ節生検術のどちらが有用か?

  土橋裕允, 田中智人, 兪史夏, 恒遠啓示, 前田和也, 芦原敬允, 寺田信一, 丸岡寛, 橋田宗祐, 田中良道, 寺井義人, 大道正英

  2018, 日本産科婦人科学会雑誌, 70(2) (2)


• 当院におけるHBOC診療体制の現況

  丸岡寛, 田中良道, 寺田信一, 古形祐平, 藤原聡枝, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2018, 産婦人科の進歩, 70(4) (4)


• 子宮頸癌における18F-FDG PET-CTの有用性

  大瀧瑠璃, 寺田信一, 上田尚子, 宮本瞬輔, 丸岡寛, 古形祐平, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 山本和宏, 鳴海善文, 大道正英

  2018, Abstracts. Annual Symposium. Japanese Society for the Advancement of Women’s Imaging, 19th


• 上皮性卵巣境界悪性腫瘍および卵巣癌におけるFDG-PET/CTのSUV max値の検討

  上田尚子, 田中智人, 大瀧瑠璃, 宮本瞬輔, 寺田信一, 丸岡寛, 古形祐平, 藤原聡枝, 田中良通, 恒遠啓示, 佐々木浩, 寺井義人, 山本和宏, 鳴海善文, 大道正英

  2018, Abstracts. Annual Symposium. Japanese Society for the Advancement of Women’s Imaging, 19th


• 凍結融解胚移植後,妊娠初期の大量腹水貯留を認め,診断に苦慮した進行胃癌の1例

  芦原敬允, 布出実紗, 佐野匠, 田中智人, 藤田太輔, 寺井義人, 大道正英

  2018, 日本周産期・新生児医学会雑誌, 54(2) (2)


• 胎児診断に至り,予後良好であったKlippel-Trenaunay-Weber症候群の2例

  佐野匠, 藤田太輔, 芦原敬允, 田中智人, 鈴木裕介, 丸岡寛, 岡本敦子, 大門篤史, 太田沙緒里, 布出実紗, 永易洋子, 寺井義人, 大道正英

  2018, 日本周産期・新生児医学会雑誌, 54(2) (2)


• First trimesterにおける鼻骨欠損・鼻骨低形成の評価について

  藤田太輔, 大門篤史, 太田沙緒里, 布出実紗, 丸岡寛, 小西博巳, 永昜洋子, 岡本敦子, 多賀紗也香, 佐野匠, 芹原敬允, 鈴木裕介, 田中智人, 寺井義人, 大道正英

  2018, 日本周産期・新生児医学会雑誌, 54(2) (2)


• 当院における出生前診断を受ける妊婦と家族の心理的支援システムの構築

  宮田郁, 小西博巳, 太田沙緒里, 布出実紗, 大門篤史, 永易洋子, 岡本敦子, 佐野匠, 芦原敬允, 鈴木裕介, 田中智人, 藤田太輔, 寺井義人, 大道正英

  2018, 日本周産期・新生児医学会雑誌, 54(2) (2)


• 産後に血栓性微小血管症をきたしたSLE合併妊娠の1例

  布出実紗, 藤田太輔, 大門篤史, 太田沙緒里, 永易洋子, 岡本敦子, 多賀紗也香, 芦原敬允, 佐野匠, 鈴木裕介, 田中智人, 寺井義人, 大道正英

  2018, 日本周産期・新生児医学会雑誌, 54(2) (2)


• 当院におけるTrial of labor after cesarean delivery(TOLAC)の検討

  岡本敦子, 藤田太輔, 大門篤史, 太田沙緒里, 布出実紗, 小西博巳, 永易洋子, 丸岡寛, 多賀紗也香, 芦原敬允, 佐野匠, 鈴木裕介, 田中智人, 寺井義人, 大道正英

  2018, 日本周産期・新生児医学会雑誌, 54(2) (2)


• 当院における腹腔鏡下子宮体癌手術の治療成績

  藤原聡枝, 寺田信一, 古形祐平, 芦原敬允, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2018, 日本産科婦人科内視鏡学会雑誌, 34(Supplement 1) (Supplement 1)


• 腹腔鏡手術を施行した妊娠合併未熟奇形腫の一例-当院の未熟奇形腫後方視的検討を加えて-

  上田尚子, 大瀧瑠璃, 宮本瞬輔, 寺田信一, 中村奈津穂, 穀内香奈, 古形祐平, 田中良通, 田中智人, 恒遠啓示, 寺井義人, 大道正英

  2018, 日本産科婦人科内視鏡学会雑誌, 34(Supplement 1) (Supplement 1)


• 腹膜透析中の子宮内膜増殖症患者に対して腹腔鏡下子宮全摘出術を施行した一例

  宮本瞬輔, 寺田信一, 小西博巳, 古形祐平, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 寺井義人, 大道正英

  2018, 日本産科婦人科内視鏡学会雑誌, 34(Supplement 1) (Supplement 1)


• 当院における腹腔鏡下広汎子宮全摘出術と開腹広汎子宮全摘出術の検討

  田中良道, 寺井義人, 村山結美, 寺田信一, 古形祐平, 藤原聡枝, 田中智人, 佐々木浩, 恒遠啓示, 大道正英

  2018, 日本産科婦人科内視鏡学会雑誌, 34(Supplement 1) (Supplement 1)


• 腹腔鏡下手術を施行した卵巣境界悪性腫瘍の予後の検討

  村山結美, 上田尚子, 中村奈津穂, 小西博巳, 穀内香奈, 古形裕平, 藤原聡枝, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, 寺井義人, 大道正英

  2018, 日本産科婦人科内視鏡学会雑誌, 34(Supplement 1) (Supplement 1)


• プラチナ感受性再発卵巣癌へのベバシズマブの有用性とプラチナフリー期間への関与

  藤原聡枝, 寺田信一, 古形祐平, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2018, 日本癌治療学会学術集会(Web), 56th


• 腹腔鏡下婦人科悪性腫瘍におけるセンチネルリンパ節ナビゲーション手術~ICGの有用性とこれから~

  田中智人, 寺井義人, 大道正英

  2018, 日本内視鏡外科学会雑誌, 23(7 (CD-ROM)) (7 (CD-ROM))


• 子宮体癌に対する腹腔鏡下手術適応拡大とさらなる低侵襲化を目指して

  寺井義人, 田中智人, 大道正英

  2018, 日本内視鏡外科学会雑誌, 23(7 (CD-ROM)) (7 (CD-ROM))


• 腹式広汎子宮頸部摘出術後妊娠3例に対する帝王切開術

  大門篤史, 藤田太輔, 布出実紗, 佐野匠, 鈴木裕介, 藤原聡枝, 田中智人, 田中良道, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2018, 産婦人科手術, (29) (29)


• エキスパートの内視鏡手術-コツとピットフォール I 子宮体がん 腹腔鏡下子宮体がん手術

  田中良道, 寺井義人, 寺田信一, 古形祐平, 芦原敬允, 藤原聡枝, 田中智人, 恒遠啓示, 大道正英

  2018, 産婦人科の実際, 67(3) (3)


• 境界悪性Brenner腫瘍の1例

  大瀧瑠璃, 田中良道, 土橋裕允, 橋田宗祐, 丸岡寛, 古形祐平, 芦原敬允, 藤原聡枝, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2018, 産婦人科の進歩, 70(2) (2)


• 当院での子宮内膜症性嚢胞に対する腹腔鏡下手術後の再発予防について

  古形祐平, 大瀧瑠璃, 田中サキ, 布出実紗, 中村奈津穂, 小西博巳, 穀内香奈, 田中智人, 恒遠啓示, 寺井義人, 大道正英

  2018, 日本産科婦人科内視鏡学会雑誌, 34(Supplement 1) (Supplement 1)


• 第一助手を育てれば,術者が育つ

  恒遠啓示, 寺井義人, 田中サキ, 寺田信一, 小西博巳, 村山結美, 穀内香奈, 古形祐平, 田中智人, 大道正英

  2018, 日本産科婦人科内視鏡学会雑誌, 34(Supplement 1) (Supplement 1)


• 非交通性副角子宮を伴う単角子宮に対し腹腔鏡補助下副角子宮摘出術を行った1例

  土橋裕允, 恒遠啓示, 小西博已, 穀内香奈, 藤原聡枝, 田中良道, 田中智人, 植木健, 寺井義人, 大道正英

  2018, 日本産科婦人科内視鏡学会雑誌, 34(Supplement 1) (Supplement 1)


• 当科で行っている腹腔鏡下神経温存広汎子宮全摘出術の実際

  寺井義人, 田中智人, 大道正英

  2018, 日本内視鏡外科学会雑誌, 23(7 (CD-ROM)) (7 (CD-ROM))


• 再発悪性腫瘍に対して,腹腔鏡下手術で腫瘍摘出しえた2例

  寺田信一, 寺井義人, 上田尚子, 宮本瞬輔, 村山結美, 多賀紗也加, 古形祐平, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 大道正英

  2018, 日本産科婦人科内視鏡学会雑誌, 34(Supplement 1) (Supplement 1)


• 13歳で手術を要した子宮筋腫の1例

  橋田宗祐, 寺田信一, 古形祐平, 芦原敬允, 藤原聡枝, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, 寺井義人, 大道正英

  2018, 産婦人科の進歩, 70(2) (2)


• 当科における妊娠中子宮頸部円錐切除症例の後方視的検討

  土橋裕允, 田中良道, 橋田宗祐, 古形祐平, 芦原敬允, 前田和也, 藤原聡枝, 兪史夏, 田中智人, 恒遠啓示, 寺井義人, 大道正英

  2018, 産婦人科手術, (29) (29)


• 卵管留水腫に対する腹腔鏡下卵管切除術(ストリップ法)前後の卵巣機能と術後妊娠率

  穀内 香奈, 奥田 喜代司, 中村 奈津穂, 田中 理恵, 佐々木 春菜, 寺尾 美輪子, 小西 博巳, 中村 真由美, 前田 和也, 林 正美, 寺井 義人, 大道 正英

  (一社)日本生殖医学会, Oct. 2017, 日本生殖医学会雑誌, 62(4) (4), 412 - 412, Japanese


• 卵巣機能低下不妊患者に対する経皮テストステロン剤の有用性の検討

  中村 真由美, 林 正美, 穀内 香奈, 中村 奈津穂, 小西 博巳, 劉 昌恵, 佐々木 春菜, 寺尾 美輪子, 寺井 義人, 大道 正英

  (一社)日本生殖医学会, Oct. 2017, 日本生殖医学会雑誌, 62(4) (4), 469 - 469, Japanese


• 当院における腹式広汎子宮頸部摘出術後の妊娠についての検討

  小西 博巳, 林 正美, 佐々木 春菜, 寺尾 美輪子, 穀内 香奈, 中村 奈津穂, 中村 真由美, 前田 和也, 寺井 義人, 大道 正英

  (一社)日本生殖医学会, Oct. 2017, 日本生殖医学会雑誌, 62(4) (4), 478 - 478, Japanese


• 血液凝固異常症 : 第Ⅻ因子・プロテインS欠乏症を含めて (今月の臨床 着床不全・流産をいかに防ぐか : PGS時代の不妊・不育症診療ストラテジー) -- (母体・子宮側因子による流産・不育症)

  藤田 太輔, 寺井 義人, 大道 正英

  医学書院, Sep. 2017, 臨床婦人科産科, 71(9) (9), 836 - 845, Japanese


• 卵管留水腫に対する腹腔鏡下卵管切除術(ストリップ法)前後の卵巣機能と術後妊娠率

  穀内 香奈, 奥田 喜代司, 中村 奈津穂, 小西 博巳, 中村 真由美, 林 正美, 田中 理恵, 寺井 義人, 大道 正英

  (一社)日本産科婦人科内視鏡学会, Aug. 2017, 日本産科婦人科内視鏡学会雑誌, 33(Suppl.I) (Suppl.I), 945 - 945, Japanese


• 卵巣予備能からみたチョコレート嚢胞への至適アプローチ AMHからみた子宮内膜症性嚢胞内壁焼灼術の有用性の検討

  中村 奈津穂, 奥田 喜代司, 穀内 香奈, 小西 博巳, 中村 真由美, 劉 昌恵, 林 正美, 山下 能毅, 寺井 義人, 大道 正英

  日本エンドメトリオーシス学会, Jul. 2017, 日本エンドメトリオーシス学会会誌, 38, 104 - 104, Japanese


• 子宮体癌2018年版・子宮頸癌2017年版 (第2章)【初回治療】に関して

  小林 裕明, 近藤 英司, 進 伸幸, 寺井 義人, 戸板 孝文, 新倉 仁, 渡利 英道, 河野 善明

  (公社)日本婦人科腫瘍学会, Jun. 2017, 日本婦人科腫瘍学会雑誌, 35(3) (3), 434 - 434, Japanese


• 3分でわかる 周産期医療キーワード2017(第15回)妊娠初期胎児超音波検査

  藤田 太輔, 寺井 義人, 大道 正英

  メディカ出版, May 2017, Perinatal care = ペリネイタルケア, 36(5) (5), 486 - 489, Japanese


• 腹腔鏡下手術 (今月の臨床 婦人科がん低侵襲治療の現状と展望) -- (子宮体がん)

  寺井 義人, 田中 智人, 古形 祐平, 芦原 敬允, 藤原 聡枝, 田中 良道, 佐々木 浩, 恒遠 啓示, 大道 正英

  医学書院, Apr. 2017, 臨床婦人科産科, 71(3) (3), 336 - 343, Japanese


• 腹腔鏡下子宮体がん手術の普及に向けて (第58回日本婦人科腫瘍学会学術講演会記録) -- (シンポジウム 婦人科悪性腫瘍鏡視下手術の展望 : 教育,普及)

  寺井 義人, 田中 智人, 芦原 敬允, 藤原 聡枝, 田中 良道, 佐々木 浩, 恒遠 啓示, 大道 正英

  日本婦人科腫瘍学会, Apr. 2017, 日本婦人科腫瘍学会雑誌, 35(2) (2), 96 - 103, Japanese


• 子宮内膜症性嚢胞内壁焼灼術におけるバイポーラ鉗子およびアルゴンプラズマコアギュレータの卵巣機能への影響

  中村 奈津穂, 奥田 喜代司, 小西 博巳, 穀内 香奈, 中村 真由美, 劉 昌恵, 林 正美, 山下 能毅, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2017, 日本産科婦人科学会雑誌, 69(2) (2), 699 - 699, Japanese


• 凍結融解胚移植における血中エストラジオール値と子宮内膜厚の関連についての検討

  劉 昌恵, 林 正美, 越田 裕一郎, 宮本 聖愛, 村山 結美, 中村 奈津穂, 小西 博巳, 中村 真由美, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2017, 日本産科婦人科学会雑誌, 69(2) (2), 848 - 848, Japanese


• 卵巣予備能評価として血清テストステロン基礎値は選択肢となりうるか

  越田 裕一郎, 劉 昌恵, 宮本 聖愛, 布出 実紗, 小西 博巳, 中村 奈津穂, 中村 真由美, 林 正美, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2017, 日本産科婦人科学会雑誌, 69(2) (2), 979 - 979, Japanese


• 転移性卵巣腫瘍における外科的治療の有用性について

  土橋裕允, 芦原敬允, 橋田宗祐, 前田和也, 藤原聡枝, 田中良道, 田中智人, 佐々木浩, 寺井義人, 大道正英

  2017, 日本産科婦人科学会雑誌, 69(2) (2)


• 当科における再発卵巣癌に対するBevacizumab併用療法の使用経験

  藤原聡枝, 田路明彦, 橋田宗祐, 芦原敬允, 田中智人, 田中良道, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2017, 日本産科婦人科学会雑誌, 69(2) (2)


• 子宮内膜癌・子宮内膜異型増殖症に対するMPA療法の治療成績

  田中良道, 橋田宗祐, 芦原敬允, 前田和也, 藤原聡枝, 田中智人, 佐々木浩, 恒遠啓示, 寺井義人, 大道正英

  2017, 日本産科婦人科学会雑誌, 69(2) (2)


• 生活習慣病からみた子宮体がんの臨床病理学的特徴

  佐々木浩, 宮本聖愛, 村山結美, 丸岡寛, 前田和也, 劉昌恵, 兪史夏, 田中智人, 寺井義人, 大道正英

  2017, 日本産科婦人科学会雑誌, 69(2) (2)


• 卵巣悪性腫瘍合併妊娠の1例

  田中サキ, 藤原聡枝, 芦原敬允, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2017, 産婦人科の進歩, 69(2) (2)


• 腹腔鏡下子宮体癌手術において,腹腔内播種のため開腹移行例の検討

  大瀧瑠璃, 藤原聡枝, 田路明彦, 橋田宗祐, 丸岡寛, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2017, 日本産科婦人科学会雑誌, 69(2) (2)


• 娩出困難な稽留流産に対しTCRを施行した1例

  前田和也, 芦原敬允, 藤原聡枝, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, 藤田太輔, 寺井義人, 猪木千春, 大道正英

  2017, 産婦人科の進歩, 69(2) (2)


• 子宮頸部癌肉腫の癌腫成分が神経内分泌腫瘍であった非常に稀な1例

  森田奈津子, 芦原敬允, 土橋裕允, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 山田隆司, 大道正英

  2017, 日本産科婦人科学会雑誌, 69(2) (2)


• 子宮頸癌で卵巣温存はどこまで可能か

  丸岡寛, 藤原聡枝, 佐々木駿, 芦原敬允, 兪史夏, 田中良道, 田中智人, 恒遠啓示, 寺井義人, 大道正英

  2017, 日本産科婦人科学会雑誌, 69(2) (2)


• 産婦人科画像診断トレーニング この所見をどう読むか?悪性腫瘍 症例:卵巣がん 2)婦人科腫瘍におけるセンチネルリンパ節生検の可能性

  寺井義人, 田中智人, 大道正英

  2017, 臨床婦人科産科, 71(4) (4)


• 2,347例のFirst trimester screeningにおける静脈管走行異常8例の検討

  藤田太輔, 佐野匠, 大野篤史, 布出実紗, 小西博己, 永易洋子, 岡本敦子, 芦原敬允, 鈴木裕介, 田中智人, 寺井義人, 大道正英

  2017, 日本周産期・新生児医学会雑誌, 53(2) (2)


• 出生後に先天性気管閉鎖症と診断した1例

  布出実紗, 藤田太輔, 大門篤史, 村山結美, 永易洋子, 小西博已, 丸岡寛, 岡本敦子, 芦原敬允, 佐野匠, 鈴木裕介, 田中智人, 寺井義人, 大道正英

  2017, 日本周産期・新生児医学会雑誌, 53(2) (2)


• 社会的ハイリスク妊産婦の検討大学病院における里親制度の支援について

  岡本敦子, 藤田大輔, 大門篤史, 布出実紗, 村山結美, 小西博巳, 永易洋子, 丸岡寛, 芦原敬允, 佐野匠, 鈴木裕介, 田中智人, 寺井義人, 大道正英, 宮田郁

  2017, 日本周産期・新生児医学会雑誌, 53(2) (2)


• 社会的ハイリスク妊産婦の支援システム~精神疾患合併妊産褥婦を中心に~

  宮田郁, 村山結実, 布出実紗, 大門篤史, 永易洋子, 岡本敦子, 佐野匠, 芦原敬允, 鈴木裕介, 田中智人, 藤田太輔, 寺井義人, 大道正英

  2017, 日本周産期・新生児医学会雑誌, 53(2) (2)


• 原発性アルドステロン症合併妊娠の一例

  森田奈津子, 藤田太輔, 大門篤史, 村山結美, 布出実紗, 永易洋子, 小西博巳, 丸岡寛, 岡本敦子, 佐野匠, 芦原敬允, 鈴木裕介, 田中智人, 寺井義人, 大道正英

  2017, 日本周産期・新生児医学会雑誌, 53(2) (2)


• 前置胎盤のMRIにおける子宮下節の占有面積率と帝王切開時出血量の予測について

  永易洋子, 藤田太輔, 大門篤史, 村山結美, 布出実紗, 小西博巳, 丸岡寛, 岡本敦子, 佐野匠, 芦原敬允, 鈴木裕介, 田中智人, 寺井義人, 大道正英

  2017, 日本周産期・新生児医学会雑誌, 53(2) (2)


• 子宮頸癌における骨盤リンパ節転移の術前術中診断:PET-CTおよびsentinel node biopsyの有用性

  田中智人, 寺井義人, 丸岡寛, 橋田宗祐, 前田和也, 芦原敬允, 藤原聡枝, 兪史夏, 田中良道, 佐々木浩, 恒遠啓示, 大道正英

  2017, 日本婦人科腫瘍学会雑誌, 35(3) (3)


• 子宮体がんに対する腹腔鏡下傍大動脈リンパ節郭清の有用性

  古形祐平, 寺井義人, 橋田宗祐, 芦原敬允, 前田和也, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 大道正英

  2017, 日本婦人科腫瘍学会雑誌, 35(3) (3)


• 子宮頸部初期病変(CIN)のHPV型と病変進展リスクについて

  田中良道, 橋田宗祐, 古形祐平, 芦原敬允, 前田和也, 藤原聡枝, 兪史夏, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2017, 日本婦人科腫瘍学会雑誌, 35(3) (3)


• 子宮頸がんに対する腹腔鏡下広汎子宮全摘出術の妥当性の検討

  橋田宗祐, 寺井義人, 田中智人, 古形祐平, 芦原敬允, 前田和也, 藤原聡枝, 田中良道, 恒遠啓示, 佐々木浩, 大道正英

  2017, 日本婦人科腫瘍学会雑誌, 35(3) (3)


• 当科で子宮頸部細胞診で「AGC」と判定された症例について

  寺田信一, 田中良道, 土橋裕允, 橋田宗祐, 丸岡寛, 古形祐平, 芦原敬允, 前田和也, 藤原聡枝, 兪史夏, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2017, 産婦人科の進歩, 69(4) (4)


• 肥満子宮体がんに対する腹腔鏡下手術の検討

  寺井義人, 田中智人, 橋田宗祐, 丸岡寛, 寺田信一, 古形祐平, 芦原敬允, 前田和也, 藤原聡枝, 佐々木浩, 大道正英

  2017, 日本女性医学学会雑誌, 25


• 婦人科悪性腫瘍でのリンパ節転移の診断における術前PET-CTの有用性

  寺田信一, 寺井義人, 橋田宗祐, 丸岡寛, 古形祐平, 前田和也, 芦原敬允, 藤原聡枝, 田中智人, 田中良道, 恒遠啓示, 佐々木浩, 大道正英

  2017, Abstracts. Annual Symposium. Japanese Society for the Advancement of Women’s Imaging, 18th


• 神経内分泌腫瘍成分を伴う子宮頸部癌肉腫の1例

  森田奈津子, 芦原敬允, 丸岡寛, 前田和也, 藤原聡枝, 田中智人, 田中良道, 寺井義人, 山田隆司, 大道正英

  2017, 日本臨床細胞学会雑誌(Web), 56


• A Case of cystic adenomyoma treated by TCR.

  前田和也, 古形祐平, 丸岡寛, 田中智人, 恒遠啓示, 寺井義人, 猪木千春, 大道正英

  2017, 日本産科婦人科内視鏡学会雑誌, 33(2) (2)


• 局所進行子宮頸癌に対する術前動注化学療法

  田中智人, 寺井義人, 丸岡寛, 橋田宗祐, 寺田信一, 古形祐平, 芦原敬之允, 前田和也, 兪史夏, 藤原聡枝, 田中良道, 恒遠啓示, 佐々木浩, 大道正英

  2017, 日本癌治療学会学術集会(Web), 55th


• 婦人科癌における高齢者へのweekly TC療法の安全性と有用性についての検討

  藤原聡枝, 古形祐平, 芦原敬允, 田中智人, 田中良道, 佐々木浩, 恒遠啓示, 寺井義人, 大道正英

  2017, 日本癌治療学会学術集会(Web), 55th


• ハイリスク症例への対応/肥満症例への対応-腹腔鏡下手術-肥満子宮体がんに対する腹腔鏡下手術の安全性評価の検討

  寺井義人, 橋田宗祐, 芦原敬允, 藤原聡枝, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, 大道正英

  2017, 産婦人科手術, (28) (28)


• 当科における婦人科悪性腫瘍術後のリンパ浮腫発症リスク因子

  橋田宗祐, 芦原敬允, 佐々木駿, 藤原聡枝, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, 寺井義人, 大道正英

  2017, 日本産科婦人科学会雑誌, 69(2) (2)


• 子宮内避妊具の抜去における子宮鏡の有用性の検討

  前田和也, 寺田信一, 丸岡寛, 古形祐平, 芦原敬允, 藤原聡枝, 田中良道, 田中智人, 佐々木浩, 寺井義人, 猪木千春, 大道正英

  2017, 日本産科婦人科内視鏡学会雑誌, 33(Supplement 1 (Web)) (Supplement 1 (Web))


• 腹腔鏡手術後に臍部周囲より動脈性に出血し緊急再手術となった1症例

  橋田宗祐, 藤原聡枝, 寺田信一, 古形祐平, 芦原敬允, 恒遠啓示, 佐々木浩, 田中智人, 寺井義人, 大道正英

  2017, 日本産科婦人科内視鏡学会雑誌, 33(Supplement 1 (Web)) (Supplement 1 (Web))


• センチネルリンパ節マッピングによるリンパ流を意識した骨盤リンパ節郭清術

  田中智人, 寺井義人, 寺田信一, 橋田宗祐, 丸岡寛, 古形祐平, 芦原敬允, 前田和也, 藤原聡枝, 田中良道, 恒遠啓示, 佐々木浩, 大道正英

  2017, 日本産科婦人科内視鏡学会雑誌, 33(Supplement 1 (Web)) (Supplement 1 (Web))


• 進行卵巣癌,腹膜癌に対して診断目的で行った腹腔鏡下手術の検討

  芦原敬允, 寺井義人, 橋田宗佑, 寺田信一, 古形祐平, 前田和也, 藤原聡枝, 田中智人, 恒遠啓示, 大道正英

  2017, 日本産科婦人科内視鏡学会雑誌, 33(Supplement 1 (Web)) (Supplement 1 (Web))


• 当院での大型子宮に対する腹腔鏡下子宮全摘出術の工夫

  寺田信一, 寺田信一, 田中智人, 田中智人, 宮本聖愛, 宮本瞬輔, 船内祐樹, 岩井恵美, 金村昌徳, 寺井義人, 大道正英

  2017, 日本産科婦人科内視鏡学会雑誌, 33(Supplement 1 (Web)) (Supplement 1 (Web))


• Mayer-Rokitansky-Kuster-Hauser(MRKH)症候群に対して腹腔鏡補助下McIndoe法を施行した3例

  佐々木浩, 寺田信一, 前田和也, 中村奈津穂, 藤原聡枝, 田中智人, 田中良道, 恒遠啓示, 寺井義人, 大道正英

  2017, 日本産科婦人科内視鏡学会雑誌, 33(Supplement 1 (Web)) (Supplement 1 (Web))


• 術前に診断が困難であった腹腔内播種病巣のため,腹腔鏡手術から開腹術移行症例の検討

  藤原聡枝, 橋田宗祐, 中村奈津穂, 芦原敬允, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2017, 日本産科婦人科内視鏡学会雑誌, 33(Supplement 1 (Web)) (Supplement 1 (Web))


• 難治性卵巣癌モデルマウスに対するCD24を標的とした高分子ミセルを用いた新規治療

  芦原敬允, 寺井義人, 土橋裕允, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 林正美, 大道正英

  2017, 日本産科婦人科学会雑誌, 69(2) (2)


• 当院におけるPPHに対する子宮動脈塞栓術とBakriバルーン使用例の検討

  大門篤史, 藤田太輔, 布出実紗, 村山結美, 小西博巳, 永易洋子, 岡本敦子, 丸岡寛, 佐野匠, 芦原敬允, 鈴木裕介, 田中智人, 寺井義人, 大道正英

  2017, 日本周産期・新生児医学会雑誌, 53(2) (2)


• 子宮体がんに対する腹腔鏡下手術における腹水細胞診

  田中智人, 寺井義人, 芦原敬允, 前田和也, 恒遠啓示, 藤原聡枝, 田中良道, 佐々木浩, 山田隆司, 大道正英

  2017, 日本臨床細胞学会雑誌(Web), 56


• 卵巣境界悪性腫瘍に対する腹腔鏡下手術の検討

  古形祐平, 寺井義人, 芦原敬允, 前田和也, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 大道正英

  2017, 日本産科婦人科内視鏡学会雑誌, 33(Supplement 1 (Web)) (Supplement 1 (Web))


• 腹腔鏡下婦人科悪性腫瘍手術における安全な視野展開と操作のコツ

  寺井義人, 田中智人, 大道正英

  2017, 日本内視鏡外科学会雑誌, 22(7 (CD-ROM)) (7 (CD-ROM))


• 鎖骨上窩リンパ節に再発を来した卵巣境界悪性腫瘍の1例

  藤原聡枝, 丸岡寛, 芦原敬允, 田中良道, 田中智人, 寺井義人, 山田隆司, 大道正英

  2017, 日本臨床細胞学会雑誌(Web), 56


• 子宮頸癌および子宮体癌におけるPET-CTとセンチネルリンパ節生検の有用性について

  佐々木駿, 田中智人, 田路明彦, 芦原敬允, 藤原聡枝, 田中良道, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2017, 日本産科婦人科学会雑誌, 69(2) (2)


• 転移性卵巣腫瘍における臨床的特徴と予後不良因子について

  芦原敬允, 前田和也, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 寺井義人, 大道正英

  2017, 日本婦人科腫瘍学会雑誌, 35(3) (3)


• 術前化学療法施行後の進行卵巣癌症例に対する後腹膜リンパ節郭清の意義

  藤原聡枝, 芦原敬允, 兪史夏, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2017, 日本婦人科腫瘍学会雑誌, 35(3) (3)


• Seromucinous borderline tumor(SMBT)の術前診断の精度について

  田路明彦, 田中良道, 土橋裕允, 前田和也, 藤原聡枝, 兪史夏, 田中智人, 恒遠啓示, 寺井義人, 大道正英

  2017, 日本産科婦人科学会雑誌, 69(2) (2)


• 子宮内膜癌における選択的サイクリン依存性キナーゼ(CDK)4/6阻害剤palbociclib(PD-0332991)の有効性

  田中智人, 寺井義人, 丸岡寛, 前田和也, 芦原敬允, 兪史夏, 藤原聡枝, 田中良道, 佐々木浩, 恒遠啓示, 大道正英

  2017, 婦人科がんバイオマーカー研究会学術集会プログラム・抄録集, 5th


• 子宮内膜症性嚢胞蒸散術後の卵巣抗ミュラー管ホルモン値、卵巣血流は術後再発予測因子となり得るか?

  中村 奈津穂, 奥田 喜代司, 穀内 香奈, 小西 博巳, 中村 真由美, 劉 昌恵, 林 篤史, 林 正美, 山下 能毅, 寺井 義人, 大道 正英

  (一社)日本生殖医学会, Oct. 2016, 日本生殖医学会雑誌, 61(4) (4), 409 - 409, Japanese


• 凍結融解胚移植における内膜の厚さと血中エストラジオール値測定の臨床的意義について

  劉 昌恵, 林 正美, 小西 博巳, 中村 奈津穂, 中村 真由美, 寺井 義人, 大道 正英

  (一社)日本生殖医学会, Oct. 2016, 日本生殖医学会雑誌, 61(4) (4), 465 - 465, Japanese


• RECOMBINANT HUMAN THROMBOMODULIN IMPROVES MATERNAL AND FETAL CONDITIONS IN MOUSE MODEL OF RECURRENT MISCARRIAGE

  Takumi Sano, Fujita Daisuke, Nagayasu Yoko, Okamoto Atsuko, Kanki Kazuyoshi, Suzuki Yusuke, Terai Yoshito, Ohmichi Masahide

  Oct. 2016, PLACENTA, 46, 104 - 104, English

  Summary international conference


• 原因不明不妊とFOXO遺伝子との関係について

  山本 輝, 山下 能毅, 斎藤 奈津穂, 林 篤史, 林 正美, 寺井 義人, 大道 正英

  (一社)日本IVF学会, Sep. 2016, 日本IVF学会誌, 19(2) (2), 77 - 77, Japanese


• 内視鏡下婦人科悪性腫瘍手術の普遍化に向けて 子宮体癌に対する腹腔鏡下傍大動脈リンパ節郭清

  林 茂徳, 山下 博, 青木 大輔, 小林 栄仁, 三木 通保, 馬場 長, 寺井 義人

  (一社)日本産科婦人科内視鏡学会, Aug. 2016, 日本産科婦人科内視鏡学会雑誌, 32(Suppl.I) (Suppl.I), 111 - 111, Japanese


• 腹腔鏡下婦人科悪性腫瘍手術の適応拡大 子宮体癌における腹腔鏡下傍大動脈リンパ節郭清 多施設共同研究(TOTOK study)

  田中 智人, 寺井 義人, 大道 正英, 林 茂徳, 青木 大輔, 三木 通保, 藤原 潔, 小林 栄仁, 木村 正, 馬場 長, 松村 謙臣

  (一社)日本産科婦人科内視鏡学会, Aug. 2016, 日本産科婦人科内視鏡学会雑誌, 32(Suppl.I) (Suppl.I), 116 - 116, Japanese


• 婦人科腫瘍におけるセンチネルリンパ節生検の可能性

  寺井 義人, 田中 智人, 大道 正英

  医学書院, May 2016, 臨床婦人科産科, 70(5) (5), 433 - 438, Japanese


• 妊娠初期胎児精査外来による羊水検査症例の検討

  佐野 匠, 藤田 太輔, 土橋 裕允, 橋田 宗祐, 澤田 雅美, 中村 真由美, 岡本 敦子, 鈴木 裕介, 神吉 一良, 林 正美, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2016, 日本産科婦人科学会雑誌, 68(2) (2), 930 - 930, Japanese


• Nuchaltranslucencyを中心とした1,555例の妊娠初期胎児超音波精査の検討

  藤田 太輔, 佐野 匠, 箕浦 彩, 澤田 雅美, 永易 洋子, 劉 昌恵, 岡本 敦子, 鈴木 裕介, 神吉 一良, 林 正美, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2016, 日本産科婦人科学会雑誌, 68(2) (2), 931 - 931, Japanese


• ギランバレー症候群合併妊娠の3例

  永易 洋子, 藤田 太輔, 箕浦 彩, 宮本 瞬輔, 澤田 雅美, 岡本 敦子, 佐野 匠, 鈴木 裕介, 神吉 一良, 林 正美, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2016, 日本産科婦人科学会雑誌, 68(2) (2), 940 - 940, Japanese


• 妊娠高血圧腎症妊婦における血管内皮機能異常と治療による改善効果の検討

  岡本 敦子, 田辺 晃子, 澤田 雅美, 中村 真由美, 劉 昌恵, 佐野 匠, 鈴木 裕介, 神吉 一良, 藤田 太輔, 林 正美, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2016, 日本産科婦人科学会雑誌, 68(2) (2), 790 - 790, Japanese


• 重症妊娠悪阻からWernicke脳症を発症した症例

  箕浦 彩, 藤田 太輔, 澤田 雅美, 永易 洋子, 中村 真由美, 岡本 敦子, 佐野 匠, 鈴木 裕介, 神吉 一良, 林 正美, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2016, 日本産科婦人科学会雑誌, 68(2) (2), 942 - 942, Japanese


• モルセレーターを使用しない腹腔鏡下子宮筋腫核出術

  平松 敦, 林 篤史, 土橋 裕允, 中村 真由美, 永易 洋子, 劉 昌恵, 高井 雅聡, 林 正美, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2016, 日本産科婦人科学会雑誌, 68(2) (2), 619 - 619, Japanese


• 卵巣チョコレート嚢胞の術後再発予防策について

  劉 昌恵, 林 篤史, 土橋 裕允, 田中 サキ, 永易 洋子, 中村 真由美, 高井 雅聡, 林 正美, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2016, 日本産科婦人科学会雑誌, 68(2) (2), 793 - 793, Japanese


• 腹腔鏡下子宮体がん手術の適応と限界 (特集 婦人科腹腔鏡手術の適応と限界を考える)

  寺井 義人, 田中 智人, 古形 祐平

  金原出版, Feb. 2016, 産婦人科の実際, 65(2) (2), 125 - 131, Japanese


• 扁平上皮癌の成分を有する卵巣癌肉腫の1例

  宮本聖愛, 藤原聡枝, 芦原敬, 兪史夏, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 山田隆司, 大道正英

  2016, 産婦人科の進歩, 68(2) (2)


• 術前に卵巣腫瘍と鑑別診断が困難であった末梢神経鞘腫の1例

  森田奈津子, 恒遠啓示, 宮本瞬輔, 芦原敬允, 兪史夏, 藤原聡枝, 田中良道, 田中智人, 寺井義人, 大道正英

  2016, 産婦人科の進歩, 68(2) (2)


• 直腸および子宮体部に浸潤したダグラス窩原発扁平上皮癌の1例

  土橋裕允, 佐々木浩, 前田和也, 芦原敬允, 兪史夏, 藤原聡枝, 田中智人, 間中良道, 恒遠啓示, 寺井義人, 大道正英

  2016, 産婦人科の進歩, 68(2) (2)


• 当科における再発卵巣癌に対するベバシズマブ併用化学療法の検討

  田中良道, 寺井義人, 古形祐平, 芦原敬允, 前田和也, YUU Saha, 藤原聡枝, 田中智人, 佐々木浩, 恒遠啓示, 金村昌徳, 大道正英

  2016, 産婦人科の進歩, 68(3) (3)


• 癌性腹膜炎との鑑別を要した悪性腹膜中皮腫の一例

  芦原敬允, 古形祐平, 前田和也, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 寺井義人, 大道正英

  2016, 日本臨床細胞学会雑誌(Web), 55


• 進行卵巣癌・腹膜癌のNAC症例における,腹水細胞診と腹腔鏡下生検の有用性について

  古形祐平, 田中良道, 芦原敬允, 前田和也, 藤原聡枝, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2016, 日本臨床細胞学会雑誌(Web), 55


• 子宮癌における捺印細胞診を用いたセンチネルリンパ節術中迅速診断

  田中智人, 寺井義人, 前田和也, 芦原敬允, 藤原聡枝, 田中良道, 恒遠啓示, 山田隆司, 大道正英

  2016, 日本臨床細胞学会雑誌(Web), 55


• 当院における社会的リスク妊婦の検討

  岡本敦子, 藤田太輔, 大門篤史, 布出実紗, 村山結美, 小西博巳, 丸岡寛, 永易洋子, 芦原敬允, 佐野匠, 神吉一良, 鈴木裕介, 田中智人, 寺井義人, 大道正英

  2016, 日本周産期・新生児医学会雑誌, 52(2) (2)


• 妊娠初期胎児1,521例における三尖弁逆流の意義について

  藤田太輔, 佐野匠, 大門篤史, 布出実紗, 村山結美, 小西博巳, 丸岡寛, 岡本敦子, 芦原敬允, 神吉一良, 鈴木裕介, 田中智人, 寺井義人, 大道正英

  2016, 日本周産期・新生児医学会雑誌, 52(2) (2)


• 診断目的で行った腹腔鏡下生検術の検討

  芦原敬允, 前田和也, 藤原聡枝, 田中智人, 田中良道, 佐々木浩, 恒遠啓示, 寺井義人, 大道正英

  2016, 日本婦人科腫瘍学会雑誌, 34(3) (3)


• 捺印細胞診で推定し得た卵巣癌肉腫の1例

  藤原聡枝, 古形祐平, 芦原敬允, 田中良道, 田中智人, 恒遠啓示, 寺井義人, 山田隆司, 大道正英

  2016, 日本臨床細胞学会雑誌(Web), 55


• 卵巣成熟嚢胞性奇形腫の悪性転化により明細胞癌を発症した一例

  前田和也, 恒遠啓示, 芦原敬允, 藤原聡枝, 田中良道, 田中智人, 佐々木浩, 寺井義人, 大道正英

  2016, 日本婦人科腫瘍学会雑誌, 34(3) (3)


• 腹腔鏡下手術により,術中および術後に卵巣境界悪性腫瘍と診断された症例の検討

  古形祐平, 芦原敬允, 前田和也, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2016, 日本婦人科腫瘍学会雑誌, 34(3) (3)


• 子宮頸癌術後再発リスク群に対する術後補助化学療法の有用性についての検討

  藤原聡枝, 古形祐平, 芦原敬允, 兪史夏, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2016, 日本婦人科腫瘍学会雑誌, 34(3) (3)


• 当院における産科危機的出血の救急受け入れ体制の試み

  永昜洋子, 藤田太輔, 大門篤史, 布出実紗, 村山結美, 小西博巳, 丸岡寛, 岡本敦子, 芦原敬允, 佐野匠, 神吉一良, 鈴木裕介, 田中智人, 寺井義人, 大道正英

  2016, 日本周産期・新生児医学会雑誌, 52(2) (2)


• 子宮頸部初期病変の細胞診・組織診不一致症例の解析

  田中良道, 寺井義人, 古形祐平, 芦原敬允, 前田和也, 藤原聡枝, 田中智人, 恒遠啓示, 佐々木浩, 大道正英

  2016, 日本臨床細胞学会雑誌(Web), 55


• 当院でベバシズマブを投与した再発卵巣癌,卵管癌,腹膜癌症例の安全性と有効性の検討

  藤原聡枝, 芦原敬允, 前田和也, 兪史夏, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, 寺井義人, 大道正英

  2016, 日本癌治療学会学術集会(Web), 54th


• 子宮体癌におけるセンチネルリンパ節生検

  田中智人, 寺井義人, 芦原敬允, 前田和也, 藤原聡枝, 愈史夏, 田中良道, 佐々木浩, 恒遠啓示, 大道正英

  2016, 日本癌治療学会学術集会(Web), 54th


• 腹腔鏡下子宮体癌手術における合併症とその対応

  田中智人, 寺井義人, 斎藤奈津穂, 芦原敬允, 前田和也, 藤原聡枝, 田中良道, 恒遠啓示, 佐々木浩, 大道正英

  2016, 日本産科婦人科内視鏡学会雑誌, 32(Supplement 1) (Supplement 1)


• 腹腔鏡下に診断,治療し得た腹膜妊娠の一例

  宮本瞬輔, 田中智人, 橋田宗佑, 古形祐平, 芦原敬允, 藤原聡枝, 田中良道, 林篤史, 寺井義人, 大道正英

  2016, 日本産科婦人科内視鏡学会雑誌, 32(Supplement 1) (Supplement 1)


• 「婦人科内視鏡手術における安全担保」ガイドラインからみた安全担保

  寺井義人, 田中智人, 田中良道, 藤原聡枝, 佐々木浩, 恒遠啓示, 大道正英

  2016, 日本産科婦人科内視鏡学会雑誌, 32(Supplement 1) (Supplement 1)


• 子宮筋腫に対する筋腫核出術を併用した腹腔鏡下単純子宮全摘出術の検討

  田中良道, 寺井義人, 芦原敬允, 前田和也, 藤原聡枝, 田中智人, 林篤史, 佐々木浩, 大道正英

  2016, 日本産科婦人科内視鏡学会雑誌, 32(Supplement 1) (Supplement 1)


• Laparoscopic Nerve Sparing Radical Hysterectomy for Cervical Cancer

  田中智人, 寺井義人, 恒遠啓示, 大道正英

  2016, 日本内視鏡外科学会雑誌, 21(7 (CD-ROM)) (7 (CD-ROM))


• Sentinel Node Biopsy for uterine cancer

  田中智人, 寺井義人, 恒遠啓示, 大道正英

  2016, 日本内視鏡外科学会雑誌, 21(7 (CD-ROM)) (7 (CD-ROM))


• 子宮頸癌におけるCD24の機能解析

  田中智人, 寺井義人, 大道正英

  2016, 婦人科がんバイオマーカー研究会学術集会プログラム・抄録集, 4th


• 腹腔鏡下手術中に膀胱鏡検査を行うことで尿路損傷を把握できた1症例

  藤原聡枝, 斎藤奈津穂, 芦原敬允, 田中良道, 田中智人, 林篤史, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2016, 日本産科婦人科内視鏡学会雑誌, 32(Supplement 1) (Supplement 1)


• 子宮癌におけるセンチネルリンパ節生検

  田中智人, 寺井義人, 古形祐平, 前田和也, 芦原敬允, 藤原聡枝, 田中良道, 佐々木浩, 恒遠啓示, 山田隆司, 大道正英

  2016, 日本婦人科腫瘍学会雑誌, 34(3) (3)


• 子宮頸部初期病変円錐切除後の再発症例の後方視的検討

  田中良道, 寺井義人, 古形祐平, 芦原敬允, 前田和也, 藤原聡枝, 田中智人, 恒遠啓示, 佐々木浩, 大道正英

  2016, 日本婦人科腫瘍学会雑誌, 34(3) (3)


• 再発卵巣境界悪性腫瘍に対し骨盤内除臓術を施行した1例

  恒遠啓示, 寺井義人, 前田和也, 古形祐平, 芦原敬允, 藤原聡枝, 兪史夏, 田中良道, 田中智人, 佐々木浩, 金村昌徳, 大道正英

  2016, 産婦人科手術, (27) (27)


• 子宮頸部初期病変円錐切除後の再発症例の後方視的検討

  田中良道, 寺井義人, 丸岡寛, 芦原啓允, 前田和也, 藤原聡枝, 田中智人, 恒遠啓示, 佐々木浩, 大道正英

  2016, 日本癌治療学会学術集会(Web), 54th


• 腹腔鏡下子宮体がん手術の普及に向けて

  寺井義人, 田中智人, 古形祐平, 芦原敬允, 前田和也, 藤原聡枝, 田中良道, 恒遠啓示, 佐々木浩, 大道正英

  2016, 日本婦人科腫瘍学会雑誌, 34(3) (3)


• 子宮筋腫摘出後妊娠における周産期予後の検討

  田中智人, 寺井義人, 大門篤史, 布出実紗, 村山結美, 小西博巳, 丸岡寛, 永易洋子, 岡本敦子, 芦原敬允, 佐野匠, 藤田太輔, 大道正英

  2016, 日本周産期・新生児医学会雑誌, 52(2) (2)


• 嚢胞性子宮腺筋腫に対し子宮鏡下摘出術を施行した一例

  前田和也, 古形祐平, 芦原敬允, 藤原聡枝, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, 寺井義人, 猪木千春, 大道正英

  2016, 日本産科婦人科内視鏡学会雑誌, 32(Supplement 1) (Supplement 1)


• 抗NMDA受容体脳炎を合併し,緊急腹腔鏡下手術を行った卵巣未熟奇形腫の1例

  芦原敬允, 前田和也, 藤原聡枝, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, 寺井義人, 大道正英

  2016, 日本産科婦人科内視鏡学会雑誌, 32(Supplement 1) (Supplement 1)


• 適応と限界を考慮した腹腔鏡下子宮体がん手術術式

  寺井義人, 田中智人, 大道正英

  2016, 日本内視鏡外科学会雑誌, 21(7 (CD-ROM)) (7 (CD-ROM))


• P2-31-10 子宮頸癌4B期の孤立性リンパ節転移は層別化因子となりうるか(Group31 子宮頸癌・治療2・合併症・予後因子,一般演題,公益社団法人日本産科婦人科学会第68回学術講演会)

  芦原 敬允, 寺井 義人, 平松 敦, 田中 サキ, 前田 和也, 藤原 聡枝, 田中 智人, 田中 良道, 佐々木 浩, 恒遠 啓示, 大道 正英

  日本産科婦人科学会, 2016, 日本産科婦人科學會雜誌, 68(2) (2), 698 - 698, Japanese


• P2-32-4 進行,再発子宮頸癌に対するシスプラチン・イリノテカン併用療法の有用性に関する検討(Group32 子宮頸癌・治療3・化学療法・再建,一般演題,公益社団法人日本産科婦人科学会第68回学術講演会)

  藤原 聡枝, 橋田 宗祐, 箕浦 彩, 高井 雅聡, 前田 和也, 芦原 敬允, 田中 智人, 田中 良道, 佐々木 浩, 恒遠 啓示, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2016, 日本産科婦人科學會雜誌, 68(2) (2), 700 - 700, Japanese


• P3-27-3 当院における腹腔鏡下子宮体癌手術の治療成績(Group92 子宮体部腫瘍・腹腔鏡手術1,一般演題,公益社団法人日本産科婦人科学会第68回学術講演会)

  田中 良道, 寺井 義人, 橋田 宗祐, 平松 敦, 芦原 敬允, 前田 和也, 高井 雅聡, 藤原 聡枝, 田中 智人, 恒遠 啓示, 佐々木 浩, 大道 正英

  日本産科婦人科学会, 2016, 日本産科婦人科學會雜誌, 68(2) (2), 896 - 896, Japanese


• P3-16-7 進行卵巣癌での腹腔内生検における細胞表面マーカーCD24の発現の意義(Group 81 卵巣腫瘍・バイオマーカー,一般演題,公益社団法人日本産科婦人科学会第68回学術講演会)

  橋田 宗祐, 佐々木 浩, 前田 和也, 芦原 敬充, 田中 智人, 藤原 聡枝, 田中 良道, 恒遠 啓示, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2016, 日本産科婦人科學會雜誌, 68(2) (2), 867 - 867, Japanese


• MW3-1 子宮内膜癌におけるpalbociclib(PD-0332991)の機能解析(ミニワークショップ3 子宮体部腫瘍,一般演題,公益社団法人日本産科婦人科学会第68回学術講演会)

  田中 智人, 宮本 瞬輔, 前田 和也, 芦原 敬允, 藤原 聡枝, 田中 良道, 佐々木 浩, 恒遠 啓示, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2016, 日本産科婦人科學會雜誌, 68(2) (2), 596 - 596, Japanese


• P2-5-8 子宮内膜癌に対するforetinibの抗腫瘍効果についての検討(Group5 子宮体部腫瘍・基礎,一般演題,公益社団法人日本産科婦人科学会第68回学術講演会)

  古形 祐平, 寺井 義人, 宮本 瞬輔, 前田 和也, 芦原 敬允, 田中 智人, 藤原 聡枝, 田中 良道, 佐々木 浩, 恒遠 啓示, 大道 正英

  日本産科婦人科学会, 2016, 日本産科婦人科學會雜誌, 68(2) (2), 632 - 632, Japanese


• 出生前診断におけるエコーの役割 (特集 週数別 エコーのみかたコツとワザ : いつ診る?どこ診る?どう伝える?)

  藤田 太輔, 寺井 義人, 大道 正英

  メディカ出版, Jan. 2016, ペリネイタルケア, 35(1) (1), 61 - 71, Japanese


• 卵巣癌 (今月の臨床 婦人科腹腔鏡手術の進歩と"落とし穴") -- (腹腔鏡手術のピットフォール)

  寺井 義人, 大道 正英

  医学書院, Nov. 2015, 臨床婦人科産科, 69(11) (11), 1066 - 1072, Japanese


• 子宮体癌に対する腹腔鏡下手術 (特集 婦人科腹腔鏡手術の最前線)

  寺井 義人, 田中 智人, 古形 祐平

  診断と治療社, Nov. 2015, 産科と婦人科, 82(11) (11), 1242 - 1247, Japanese


• 微小浸潤癌への円錐切除術 (今月の臨床 がん妊孕性温存治療の適応と注意点 : 腫瘍学と生殖医学の接点) -- (婦人科腫瘍学 : 子宮頸癌)

  恒遠 啓示, 寺井 義人, 大道 正英

  医学書院, Sep. 2015, 臨床婦人科産科, 69(9) (9), 820 - 825, Japanese


• 異所性妊娠に対する待機療法の検討

  八田 幸治, 林 篤史, 中村 真由美, 岡本 敦子, 劉 昌恵, 小野 賀大, 林 正美, 寺井 義人, 大道 正英

  「産婦人科の進歩」編集室, May 2015, 産婦人科の進歩, 67(2) (2), 212 - 212, Japanese


• 子宮内膜癌における腹腔鏡下手術 (特集 子宮内膜癌治療の最前線) -- (子宮内膜癌に対する手術療法)

  寺井 義人, 田中 智人, 古形 祐平

  金原出版, May 2015, 産婦人科の実際, 64(5) (5), 635 - 641, Japanese


• 早産に対する黄体ホルモン療法の展望 (今月の臨床 早産の予知・予防の新たな展開) -- (早産の予防)

  藤田 太輔, 寺井 義人, 大道 正英

  医学書院, Apr. 2015, 臨床婦人科産科, 69(3) (3), 313 - 319, Japanese


• テストステロンの抗癌剤からの卵巣保護作用の検討

  劉 昌恵, 田辺 晃子, 中村 真由美, 八田 幸治, 芦原 敬允, 小野 賀大, 中村 起代子, 林 篤史, 藤田 太輔, 林 正美, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2015, 日本産科婦人科学会雑誌, 67(2) (2), 752 - 752, Japanese


• 子宮内膜症における低テストステロン環境の顆粒膜細胞に対する影響の検討

  小野 賀大, 田辺 晃子, 林 正美, 藤田 太輔, 林 篤史, 八田 幸治, 劉 昌恵, 田吹 邦雄, 中村 真由美, 大門 篤史, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2015, 日本産科婦人科学会雑誌, 67(2) (2), 898 - 898, Japanese


• 血清テストステロン値は卵巣予備能の指標として有用性である

  林 篤史, 林 正美, 高 智恵, 中村 真由美, 劉 昌恵, 小野 賀大, 渡辺 綾子, 藤田 太輔, 田辺 晃子, 寺井 義人, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2015, 日本産科婦人科学会雑誌, 67(2) (2), 731 - 731, Japanese


• 当院における顆粒膜細胞腫症例の検討

  宮本瞬輔, 田中良道, 箕浦彩, 古形祐平, 前田和也, 中村路彦, 藤原聡枝, 田中智人, 佐々木浩, 金村昌徳, 寺井義人, 大道正英

  2015, 日本産科婦人科学会雑誌, 67(2) (2)


• 腹腔鏡下生検にて診断した原発不明血管肉腫の1例

  古形祐平, 佐々木浩, 芦原敬允, 前田和也, 藤原聡枝, 兪史夏, 田中智人, 田中良道, 恒遠啓示, 金村昌徳, 寺井義人, 大道正英

  2015, 産婦人科の進歩, 67(2) (2)


• 腹腔鏡下広汎子宮全摘術

  田中智人, 寺井義人, 古形祐平, 芦原敬允, 前田和也, 高井雅聡, 田中良道, 藤原聡枝, 恒遠啓示, 佐々木浩, 大道正英

  2015, 日本産科婦人科内視鏡学会雑誌, 31(Supplement 1) (Supplement 1)


• 腹腔鏡下生検にて診断した原発不明血管肉腫の1例

  佐々木浩, 寺井義人, 古形祐平, 芦原敬允, 藤原聡枝, 田中智人, 田中良道, 恒遠啓示, 金村昌徳, 大道正英

  2015, 日本産科婦人科内視鏡学会雑誌, 31(Supplement 1) (Supplement 1)


• 子宮体がん 早期例の腹腔鏡から進行例にかけての手術の実際

  寺井義人, 田中智人, 佐々木浩, 田中良道, 古形祐平, 藤原聡枝, 兪史夏, 芦原敬允, 前田和也, 恒遠啓示, 金村昌徳, 大道正英

  2015, 日本婦人科腫瘍学会雑誌, 33(3) (3)


• 術前早期子宮体癌に対し腹腔鏡下準広汎子宮全摘術を施行することで,傍腟結合織への転移の診断が可能であった1例

  芦原敬允, 寺井義人, 前田和也, 藤原聡枝, 田中良道, 田中智人, 林篤史, 恒遠啓示, 金村昌徳, 大道正英

  2015, 日本産科婦人科内視鏡学会雑誌, 31(Supplement 1) (Supplement 1)


• 卵管間質部妊娠に対し,腹腔鏡下手術が有用であった3例

  古形祐平, 林篤史, 中村真由美, 芦原敬允, 前田和也, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 寺井義人, 大道正英

  2015, 日本産科婦人科内視鏡学会雑誌, 31(Supplement 1) (Supplement 1)


• モルセレーターを使用しない腹腔鏡下子宮筋腫核出術

  林篤史, 寺井義人, 中村真由美, 古形祐平, 前田和也, 芦原敬允, 藤原聡恵, 田中智人, 田中良道, 恒遠啓示, 佐々木浩, 大道正英

  2015, 日本産科婦人科内視鏡学会雑誌, 31(Supplement 1) (Supplement 1)


• 保険適応となった腹腔鏡下子宮体がん手術の現状と今後

  寺井義人, 田中智人, 古形祐平, 芦原敬允, 前田和也, 兪史夏, 藤原聡枝, 田中良道, 恒遠啓示, 佐々木浩, 大道正英

  2015, 日本産科婦人科内視鏡学会雑誌, 31(Supplement 1) (Supplement 1)


• 子宮体癌臍転移Sister Mary Joseph’s noduleの2例

  古形祐平, 田中良道, 芦原敬允, 前田和也, 中村路彦, 藤原聡枝, 田中智人, 恒遠啓示, 佐々木浩, 金村昌徳, 寺井義人, 大道正英

  2015, 日本婦人科腫瘍学会雑誌, 33(3) (3)


• 術前動注化学療法を施行した局所進行子宮頸癌に対する術後補助療法に関する検討

  藤原聡枝, 古形祐平, 芦原敬允, 兪史夏, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, 金村昌徳, 寺井義人, 大道正英

  2015, 日本婦人科腫瘍学会雑誌, 33(3) (3)


• 内膜細胞診が診断に有用であったタモキシフェン内服後に子宮癌肉腫を発症した2例

  古形祐平, 藤原聡枝, 芦原敬允, 田中智人, 田中良道, 金村昌徳, 寺井義人, 山田隆司, 大道正英

  2015, 日本臨床細胞学会雑誌(Web), 54


• 分葉状内頸部腺過形成(LEGH)との共存がみられた子宮頸部腺癌の1例

  前田和也, 田中良道, 芦原敬允, 藤原聡枝, 田中智人, 恒遠啓示, 佐々木浩, 金村昌徳, 寺井義人, 大道正英

  2015, 日本臨床細胞学会雑誌(Web), 54


• 当院における再発卵巣癌に対するアバスチン併用化学療法の検討

  田中良道, 寺井義人, 古形祐平, 芦原敬允, 前田和也, 藤原聡枝, 兪史夏, 田中智人, 佐々木浩, 恒遠啓示, 金村昌徳, 大道正英

  2015, 産婦人科の進歩, 67(4) (4)


• 骨盤リンパ節郭清における陰部大腿皮神経損傷

  田中智人, 寺井義人, 芦原敬允, 前田和也, 劉昌恵, 中村路彦, 高井雅聡, 藤原聡枝, 田中良道, 佐々木浩, 恒遠啓示, 金村昌徳, 大道正英

  2015, 産婦人科手術, (26) (26)


• 予後不良な子宮体癌に関する組織型からの検討

  芦原敬允, 前田和也, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 金村昌徳, 寺井義人, 大道正英

  2015, 日本癌治療学会学術集会(Web), 53rd


• 再発,進行子宮頸癌に対するシスプラチン・イリノテカン併用療法に関する検討

  藤原聡枝, 寺井義人, 古形祐平, 芦原敬允, 田中智人, 田中良道, 佐々木浩, 恒遠啓示, 金村昌徳, 大道正英

  2015, 日本癌治療学会学術集会(Web), 53rd


• 子宮癌に対するセンチネルリンパ節生検

  田中智人, 寺井義人, 古形祐平, 前田和也, 芦原敬允, 藤原聡枝, 田中良道, 恒遠啓示, 佐々木浩, 兪史夏, 金村昌徳, 山田隆司, 大道正英

  2015, 日本婦人科腫瘍学会雑誌, 33(3) (3)


• 子宮癌のセンチネルリンパ節術中診断における迅速捺印細胞診の有用性

  田中智人, 寺井義人, 古形祐平, 前田和也, 芦原敬允, 田中良道, 藤原聡枝, 金村昌徳, 山田隆司, 大道正英

  2015, 日本臨床細胞学会雑誌(Web), 54


• 子宮体癌の筋層浸潤評価における,術前MRI検査と術中迅速病理診断の有用性

  土橋裕允, 古形祐平, 橋田宗祐, 宮本瞬輔, 芦原敬允, 前田和也, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 金村昌徳, 寺井義人, 大道正英

  2015, Abstracts. Annual Symposium. Japanese Society for the Advancement of Women’s Imaging, 16th


• 腹腔鏡下手術により診断が可能であった子宮奇形の1例

  藤原聡枝, 箕浦彩, 田中智人, 永易洋子, 古形祐平, 中村真由美, 前田和也, 芦原敬充, 林篤史, 寺井義人, 大道正英

  2015, 日本産科婦人科内視鏡学会雑誌, 31(Supplement 1) (Supplement 1)


• 内膜症における低テストステロン環境の卵胞顆粒膜細胞に対する影響

  田辺晃子, 小野賀大, 田中智人, 林篤史, 寺井義人, 大道正英

  2015, 日本抗加齢医学会総会プログラム・抄録集, 15th


• 子宮頸がんに対する腹腔鏡下広汎子宮全摘出術

  寺井義人, 田中智人, 古形祐平, 中村真由美, 芦原敬允, 前田和也, 兪史夏, 藤原聡枝, 中村路彦, 田中良道, 恒遠啓示, 佐々木浩, 金村昌徳, 大道正英

  2015, 産婦人科手術, (26) (26)


• 早期子宮体癌に対する腹腔鏡下手術についての検討

  藤原聡枝, 寺井義人, 芦原敬允, 前田和也, 中村路彦, 兪史夏, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 金村昌徳, 大道正英

  2015, 産婦人科手術, (26) (26)


• 遺残子宮内膜症から発生したと考えられる癌肉腫の1例

  中村路彦, 田中良道, 古形祐平, 前田和也, 芦原敬允, 兪史夏, 藤原聡枝, 田中智人, 恒遠啓示, 佐々木浩, 金村昌徳, 寺井義人, 大道正英

  2015, 産婦人科の進歩, 67(2) (2)


• 先進医療に基づく子宮頸癌に対する腹腔鏡下広汎子宮全摘術の導入

  寺井義人, 田中智人, 古形祐平, 芦原敬允, 前田和也, 藤原聡枝, 田中良道, 恒遠啓示, 佐々木浩, 大道正英

  2015, 日本内視鏡外科学会雑誌, 20(7 (CD-ROM)) (7 (CD-ROM))


• P3-27-1 卵巣予備能を考慮した子宮内膜症性嚢胞に対する手術療法の選択(Group129 子宮内膜症1 薬物療法,一般演題,公益社団法人日本産科婦人科学会第67回学術講演会)

  斉藤 奈津穂, 奥田 喜代司, 穀内 香奈, 深澤 祐子, 中村 容子, 山下 能毅, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 884 - 884, Japanese


• P3-35-10 当院における19年間のTrial of labor after cesarean deliveryの管理について(Group137 子宮破裂 TOLAC,一般演題,公益社団法人日本産科婦人科学会第67回学術講演会)

  平松 敦, 藤田 太輔, 岡本 敦子, 田中 サキ, 高 智恵, 佐野 匠, 田中 健太郎, 神吉 一良, 鈴木 裕介, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 909 - 909, Japanese


• P1-12-1 子宮頸部筋腫に対する腹腔鏡下子宮全摘術(Group12 腹腔鏡下手術1,一般演題,公益社団法人日本産科婦人科学会第67回学術講演会)

  奥田 喜代司, 深澤 祐子, 斉藤 奈津穂, 中村 容子, 穀内 香奈, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 561 - 561, Japanese


• P3-43-6 抗リン脂質抗体陽性妊婦13例の検討(Group145 合併症妊娠8,一般演題,公益社団法人日本産科婦人科学会第67回学術講演会)

  佐野 匠, 藤田 太輔, 平松 敦, 中村 真由美, 岡本 敦子, 田中 健太郎, 鈴木 裕介, 神吉 一良, 林 正美, 田辺 晃子, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 933 - 933, Japanese


• P3-43-2 当院における膠原病合併妊娠の周産期予後の検討(Group145 合併症妊娠8,一般演題,公益社団法人日本産科婦人科学会第67回学術講演会)

  大門 篤史, 藤田 太輔, 岡本 敦子, 田中 健太郎, 佐野 匠, 芦原 敬允, 中村 路彦, 神吉 一良, 鈴木 裕介, 林 篤史, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 931 - 931, Japanese


• P3-44-9 帝王切開術後におけるVTE発症予防について : 低分子ヘパリン(エノキサパリン)の導入(Group146 合併症妊娠9,一般演題,公益社団法人日本産科婦人科学会第67回学術講演会)

  箕浦 彩, 神吉 一良, 田中 健太郎, 岡本 敦子, 劉 昌恵, 佐野 匠, 渡辺 綾子, 鈴木 裕介, 林 篤史, 藤田 太輔, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 936 - 936, Japanese


• P2-33-5 体外受精治療における化学的流産周期の予測・早期診断(Group 74 生殖補助医療3 妊娠予後,一般演題,公益社団法人日本産科婦人科学会第67回学術講演会)

  中村 真由美, 林 篤史, 田中 サキ, 箕浦 彩, 八田 幸治, 田中 良道, 恒遠 啓示, 佐々木 浩, 林 正美, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 734 - 734, Japanese


• P2-44-7 有経子宮頸癌女性に対する治療の骨密度への影響とエストロゲン補充による改善効果(Group 85 更年期2 治療,一般演題,公益社団法人日本産科婦人科学会第67回学術講演会)

  高井 雅聡, 田辺 晃子, 金村 昌徳, 恒遠 啓示, 兪 史夏, 藤原 聡枝, 渡辺 綾子, 中村 起代子, 八田 幸治, 平松 敦, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 764 - 764, Japanese


• P3-9-4 子宮内膜癌・子宮内膜異型増殖症に対するMPA療法後の再発率について(Group 111 子宮体部腫瘍 治療3 ホルモン療法,一般演題,第67回学術講演会)

  田中 良道, 寺井 義人, 前田 和也, 中村 路彦, 高井 雅聡, 藤原 聡枝, 恒遠 啓示, 佐々木 浩, 林 正美, 田辺 晃子, 金村 昌徳, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 839 - 839, Japanese


• P3-10-6 肥満子宮体がんに対しては腹腔鏡下手術と開腹手術のどちらがよいか?(Group 112 子宮体部腫瘍 治療4 腹腔鏡手術,一般演題,第67回学術講演会)

  高 智恵, 寺井 義人, 橋田 宗祐, 大門 篤史, 藤原 聡枝, 田中 智人, 田中 良道, 林 篤史, 恒遠 啓示, 佐々木 浩, 金村 昌徳, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 842 - 842, Japanese


• P3-4-1 術前化学療法施行した子宮頸癌に対する術後補助療法に関する検討(Group 106 子宮頸部腫瘍 治療1,一般演題,第67回学術講演会)

  藤原 聡枝, 寺井 義人, 橋田 宗祐, 大門 篤史, 古形 祐平, 劉 昌恵, 兪 史夏, 田中 良道, 恒遠 啓示, 佐々木 浩, 金村 昌徳, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 826 - 826, Japanese


• NW-18-2 手術適応外とされる18trisomy症候群に合併した心室中隔欠損症に対する外科治療介入の臨床像(ミニワークショップ18 胎児異常の諸問題,一般演題,公益社団法人日本産科婦人科学会第67回学術講演会)

  岡本 敦子, 藤田 太輔, 林 篤史, 神吉 一良, 鈴木 裕介, 佐野 匠, 田中 健太郎, 古形 祐平, 大門 篤史, 宮本 瞬輔, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 527 - 527, Japanese


• P2-8-2 子宮内膜癌における卵巣静脈中エストラジオール濃度(Group49 子宮体部腫瘍 症例検討,一般演題,公益社団法人日本産科婦人科学会第67回学術講演会)

  田中 サキ, 田中 智人, 金村 昌徳, 佐々木 浩, 恒遠 啓示, 藤原 聡枝, 高井 雅聡, 中村 路彦, 芦原 敬允, 前田 和也, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 669 - 669, Japanese


• P2-18-8 当院における穎粒膜細胞腫症例の検討(Group 59 卵巣腫瘍 症例検討1,一般演題,公益社団法人日本産科婦人科学会第67回学術講演会)

  宮本 瞬輔, 田中 良道, 箕浦 彩, 古形 祐平, 前田 和也, 中村 路彦, 藤原 聡枝, 田中 智人, 佐々木 浩, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 699 - 699, Japanese


• P3-15-9 術前化学療法によりpathological CRを得た進行卵巣癌症例7例の後方視的検討(Group 117 卵巣腫瘍 診断2,一般演題,第67回学術講演会)

  橋田 宗祐, 佐々木 浩, 宮本 瞬輔, 古形 祐平, 前田 和也, 藤原 聡枝, 田中 智人, 田中 良道, 恒遠 啓示, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 856 - 856, Japanese


• P3-23-4 腹腔鏡と子宮鏡による同時手術を必要とした症例の検討(Group 125 子宮鏡,一般演題,第67回学術講演会)

  穀内 香奈, 奥田 喜代司, 斉藤 奈津穂, 中村 容子, 深澤 祐子, 中村 路彦, 猪木 千春, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2015, 日本産科婦人科學會雜誌, 67(2) (2), 874 - 874, Japanese


• 血清テストステロン値は卵巣予備能の指標として有用である

  中村 真由美, 林 篤史, 岡本 敦子, 田吹 邦雄, 劉 昌恵, 小野 賀大, 林 正美, 寺井 義人, 大道 正英

  (一社)日本生殖医学会, Oct. 2014, 日本生殖医学会雑誌, 59(4) (4), 375 - 375, Japanese


• 子宮内膜症における低テストステロン環境の顆粒膜細胞に対する影響の検討

  田吹 邦雄, 小野 賀大, 岡本 敦子, 中村 真由美, 劉 昌恵, 林 篤史, 林 正美, 寺井 義人, 大道 正英

  (一社)日本生殖医学会, Oct. 2014, 日本生殖医学会雑誌, 59(4) (4), 436 - 436, Japanese


• 腹腔鏡下骨盤リンパ節郭清手術 (今月の臨床 あなたにもできる 最先端の婦人科手術)

  寺井 義人, 田中 智人, 大道 正英

  医学書院, Jul. 2014, 臨床婦人科産科, 68(7) (7), 628 - 634, Japanese


• 内膜症細胞に対するジエノゲストのデコリン分泌を介した抗増殖作用について

  小野 賀大, 寺井 義人, 村山 結美, 山本 輝, 林 篤史, 中村 容子, 吉田 陽子, 川邉 紗智子, 林 正美, 田辺 晃子, 山下 能毅, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2014, 日本産科婦人科学会雑誌, 66(2) (2), 845 - 845, Japanese


• 閉経後Sertoli細胞腫の1例

  宮本瞬輔, 村山結美, 芦原敬允, 劉昌恵, 川口浩史, 前田和也, 中村路彦, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 金村昌徳, 寺井義人, 北田文則, 大道正英

  2014, 産婦人科の進歩, 66(2) (2)


• 腹腔鏡下子宮全摘術における術式の工夫~筋腫核出術併用の有効性~

  林篤史, 寺井義人, 八田幸治, 吉田陽子, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 大道正英

  2014, 日本産科婦人科内視鏡学会雑誌, 30(Supplement 1) (Supplement 1)


• 子宮頸部明細胞腺癌の1例

  藤原聡枝, 芦原敬充, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, 金村昌徳, 寺井義人, 山田隆司, 大道正英

  2014, 日本臨床細胞学会雑誌, 53


• 子宮内膜癌は閉経後においても卵巣の影響をうけているか

  芦原敬允, 田中智人, 川口浩史, 前田和也, 丸岡理紗, 劉昌恵, 中村路彦, 高井雅聡, 藤原聡枝, 兪史夏, 田中良道, 佐々木浩, 恒遠啓示, 田辺晃子, 金村昌徳, 寺井義人, 大道正英

  2014, 日本婦人科腫瘍学会雑誌, 32(3) (3)


• 腹腔鏡下神経温存広汎子宮全摘術

  田中智人, 寺井義人, 芦原敬允, 中村路彦, 前田和也, 劉昌恵, 高井雅聡, 藤原聡枝, 兪史夏, 田中良道, 佐々木浩, 恒遠啓示, 金村昌徳, 大道正英

  2014, 日本産科婦人科内視鏡学会雑誌, 30(Supplement 1) (Supplement 1)


• 閉経後Sertoli細胞腫の1例

  村山結美, 田中良道, 藤原聡枝, 田中智人, 恒遠啓示, 佐々木浩, 金村昌徳, 寺井義人, 山田隆司, 大道正英

  2014, 日本臨床細胞学会雑誌, 53


• 子宮頸癌術後再発リスク群に対する術後補助化学療法の検討

  藤原聡枝, 劉昌恵, 芦原敬允, 前田和也, 川口浩史, 中村路彦, 高井雅聡, 兪史夏, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, 金村昌徳, 寺井義人, 大道正英

  2014, 日本婦人科腫瘍学会雑誌, 32(3) (3)


• 産科領域手術の進歩/妊娠中の腹腔鏡下手術 妊娠中の卵巣腫瘍に対する腹腔鏡下手術

  寺井義人, 林篤史, 藤原聡枝, 兪史夏, 田中智人, 田中良道, 藤田太輔, 恒遠啓示, 佐々木浩, 金村昌徳, 山下能毅, 亀谷英輝, 大道正英

  2014, 産婦人科手術, (25) (25)


• 子宮体がんに対する腹腔鏡下手術の現状と今後の展開

  寺井義人, 田中智人, 古形祐平, 中村真由美, 芦原敬允, 前田和也, 兪史夏, 藤原聡枝, 中村路彦, 田中良道, 恒遠啓示, 佐々木浩, 金村昌徳, 大道正英

  2014, 日本産科婦人科内視鏡学会雑誌, 30(Supplement 1) (Supplement 1)


• 子宮体癌の病理学的悪性度から見た拡散強調画像の有用性の検討

  斉藤奈津穂, 田中智人, 前田和也, 劉昌恵, 芦原敬允, 川口浩史, 中村路彦, 高井雅聡, 藤原聡枝, 兪史夏, 田中良道, 恒遠啓示, 佐々木浩, 金村昌徳, 寺井義人, 山本和宏, 大道正英

  2014, 日本婦人科腫瘍学会雑誌, 32(3) (3)


• 妊娠中の子宮頸部円錐切除術の留置点について

  芦原敬允, 田中良道, 前田和也, 中村路彦, 藤原聡枝, YOO Saha, 田中智人, 恒遠啓示, 金村昌徳, 寺井義人, 大道正英

  2014, 産婦人科の進歩, 66(3) (3)


• 所進行子宮頸癌に対するfour-lumen double-balloon catheterを用いた術前動注化学療法

  田中智人, 寺井義人, 芦原敬允, 川口浩史, 前田和也, 劉昌恵, 中村路彦, 高井雅聡, 藤原聡枝, 兪史夏, 田中良道, 佐々木浩, 恒遠啓示, 金村昌徳, 大道正英

  2014, 日本癌治療学会学術集会(CD-ROM), 52nd


• 抗癌剤誘発性の早発卵巣機能不全に対するテストステロンの予防効果-基礎的検討-

  田辺晃子, 小野賀大, 劉昌恵, 中村起代子, 丸岡理紗, 田中智人, 山下能毅, 寺井義人, 大道正英

  2014, 日本抗加齢医学会総会プログラム・抄録集, 14th


• 子宮体がんにおけるセンチネルリンパ節生検

  寺井義人, 田中智人, 佐々木浩, 田中良道, 劉昌恵, 古形祐平, 中村真由美, 藤原聡枝, 兪史夏, 芦原敬允, 前田和也, 中村路彦, 恒遠啓示, 金村昌徳, 大道正英

  2014, 日本癌治療学会学術集会(CD-ROM), 52nd


• 子宮頚部横紋筋肉腫の一例

  寺田信一, 前田和也, 芦原敬允, 劉昌恵, 中村路彦, 藤原聡枝, 兪史夏, 田中智人, 田中良道, 佐々木浩, 恒遠啓示, 金村昌徳, 寺井義人, 大道正英

  2014, 日本婦人科腫瘍学会雑誌, 32(3) (3)


• 性腺ホルモン供給源としての閉経後卵巣~閉経女性の健康に与える光と影~

  田辺晃子, 丸岡理紗, 渡辺綾子, 高井雅聡, 劉昌恵, 芦原敬允, 田中智人, 寺井義人, 大道正英

  2014, 日本産科婦人科栄養・代謝研究会誌, 20(1) (1)


• 早期子宮体癌に対する腹腔鏡下準広汎子宮全摘術

  田中智人, 寺井義人, 大道正英

  2014, 日本内視鏡外科学会雑誌, 19(7) (7)


• 当科における子宮体癌腹腔鏡下手術とその工夫

  佐々木浩, 寺井義人, 藤原聡枝, 田中智人, 田中良道, 恒遠啓示, 金村昌徳, 大道正英

  2014, 日本産科婦人科内視鏡学会雑誌, 30(Supplement 1) (Supplement 1)


• 子宮頸部横紋筋肉腫(ブドウ状肉腫)の一例

  前田和也, 田中良道, 藤原聡枝, 田中智人, 恒遠啓示, 佐々木浩, 金村昌徳, 寺井義人, 山田隆司, 大道正英

  2014, 日本臨床細胞学会雑誌, 53


• 早期子宮体癌に対する腹腔鏡下手術

  田中智人, 寺井義人, 芦原敬允, 前田和也, 劉昌恵, 中村路彦, 川口浩史, 高井雅聡, 兪史夏, 藤原聡枝, 田中良道, 恒遠啓示, 金村昌徳, 大道正英

  2014, 産婦人科手術, (25) (25)


• 卵巣線維腫に対する腹腔鏡下手術の有用性について

  田中良道, 藤原聡枝, 田中智人, 林篤史, 佐々木浩, 恒遠啓示, 寺井義人, 大道正英

  2014, 日本産科婦人科内視鏡学会雑誌, 30(Supplement 1) (Supplement 1)


• 子宮体部類内膜腺癌術後に発生した腟癌肉腫の1例

  中村路彦, 田中智人, 川口浩史, 芦原敬允, 藤原聡枝, 恒遠啓示, 佐々木浩, 金村昌徳, 寺井義人, 大道正英

  2014, 日本臨床細胞学会雑誌, 53


• 右房内に伸展した血管内子宮筋腫の1例

  橋田宗佑, 恒遠啓示, 古形祐平, 吉村真由美, 前田和也, 芦原敬允, 劉昌恵, 川口浩史, 中村路彦, 藤原聡枝, 田中智人, 田中良道, 佐々木浩, 金村昌徳, 寺井義人, 大道正英

  2014, 産婦人科の進歩, 66(2) (2)


• P2-51-7 子宮頸癌術後再発リスク群に対する術後補助化学療法の検討(Group 89 子宮頸部腫瘍・治療1,一般演題,公益社団法人日本産科婦人科学会第66回学術講演会)

  梅嵜 乃斗香, 藤原 聡枝, 太田 沙緒里, 前田 和也, 川口 浩史, 田中 良道, 田中 智人, 恒遠 啓示, 佐々木 浩, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 732 - 732, Japanese


• P2-54-7 卵巣癌におけるCD24の発現意義と機能解析について(Group 92 卵巣腫瘍・基礎3,一般演題,公益社団法人日本産科婦人科学会第66回学術講演会)

  芦原 敬允, 中村 起代子, 中村 路彦, 兪 史夏, 田中 良道, 田中 智人, 佐々木 浩, 恒遠 啓示, 田辺 晃子, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 740 - 740, Japanese


• MW-15-1 ヒト子宮筋腫組織皮下移植マウスモデルにおける腫瘍発育の多様性に関する検討(ミニワークショップ15 子宮筋腫・基礎と臨床,一般演題,公益社団法人日本産科婦人科学会第66回学術講演会)

  鈴木 裕介, 寺田 信一, 太田 沙緒里, 布出 実紗, 村山 結美, 中村 路彦, 神吉 一良, 高井 雅聡, 金村 昌徳, 田辺 晃子, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 455 - 455, Japanese


• P1-9-6 Uterine smooth muscle tumor of uncertain malignant potential(STUMP)7例の臨床病理学的検討(Group 9 子宮体部腫瘍・症例2,一般演題,公益社団法人日本産科婦人科学会第66回学術講演会)

  平松 敦, 恒遠 啓示, 徳重 悠, 宮本 瞬輔, 芦原 敬允, 前田 和也, 中村 路彦, 藤原 聡枝, 田中 良道, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 495 - 495, Japanese


• P1-11-7 妊娠中のCIN症例の管理について(Group 11 CIN・その他・診断・治療1,一般演題,公益社団法人日本産科婦人科学会第66回学術講演会)

  宮本 瞬輔, 田中 良道, 兪 史夏, 藤原 聡枝, 田中 智人, 藤田 太輔, 恒遠 啓示, 金村 昌徳, 寺井 義人, 亀谷 英輝, 北田 文則, 大道 正英

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 502 - 502, Japanese


• P1-19-4 子宮頸癌および子宮体癌に対するセンチネルリンパ節生検(Group 19 悪性腫瘍全般・診断2,一般演題,公益社団法人日本産科婦人科学会第66回学術講演会)

  田中 智人, 寺井 義人, 芦原 敬允, 前田 和也, 川口 浩史, 中村 路彦, 藤原 聡枝, 田中 良道, 佐々木 浩, 恒遠 啓示, 金村 昌徳, 大道 正英

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 520 - 520, Japanese


• 1. 妊娠中の婦人科良性・悪性腫瘍 : 検診,診断,治療(クリニカルカンファレンス3-Subspecialtyを越えて(周産期・腫瘍)-,生涯研修プログラム,公益社団法人日本産科婦人科学会第66回学術講演会)

  寺井 義人

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 371 - 371, Japanese


• 3. 難治性卵巣癌の浸潤・転移に関わる分子をターゲットとした新規治療法の開発(難治性卵巣癌の克服を目指して,シンポジウム2(腫瘍),公益社団法人日本産科婦人科学会第66回学術講演会)

  寺井 義人

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 341 - 342, Japanese


• P2-10-3 婦人科悪性腫瘍手術周術期管理におけるCK値の意義(Group48 悪性腫瘍全般・治療3,一般演題,公益社団法人日本産科婦人科学会第66回学術講演会)

  前田 和也, 恒遠 啓示, 寺田 信一, 川口 浩史, 劉 昌恵, 中村 路彦, 藤原 聡枝, 田中 良道, 佐々木 浩, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 610 - 610, Japanese


• P2-7-3 腹腔鏡下子宮全摘術における術式の工夫 : 筋腫核出術併用の有効性(Group45 腹腔鏡下手術2,一般演題,公益社団法人日本産科婦人科学会第66回学術講演会)

  徳重 悠, 林 篤史, 宮本 瞬輔, 太田 沙緒里, 小野賀 大, 中村 容子, 山本 輝, 吉田 陽子, 山下 能毅, 寺井 義人, 奥田 喜代司, 大道 正英

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 602 - 602, Japanese


• P2-8-2 婦人科悪性腫瘍に対するTC療法が及ぼす動脈硬化への影響とその予防について(Group46 悪性腫瘍全般・治療1,一般演題,公益社団法人日本産科婦人科学会第66回学術講演会)

  渡辺 綾子, 田辺 晃子, 徳重 悠, 丸岡 理紗, 八田 幸治, 中村 路彦, 中村 起代子, 高井 雅聡, 佐々木 浩, 恒遠 啓示, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 605 - 605, Japanese


• P2-39-5 習慣性流産および胎児発育不全におけるAnnexinA5の発現の免疫組織学的検討(Group 77 不育症・流産,一般演題,第66回学術講演会)

  佐野 匠, 藤田 太輔, 村山 結美, 田中 健太郎, 宮本 瞬輔, 鈴木 裕介, 神吉 一良, 渡辺 綾子, 田辺 晃子, 寺井 義人, 亀谷 英輝, 大道 正英

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 690 - 690, Japanese


• P3-27-5 子宮内膜症性嚢胞の内壁焼灼術は卵巣予備能の低下を回避できるか?(Group 124 子宮内膜症・臨床3,一般演題,公益社団法人日本産科婦人科学会第66回学術講演会)

  斉藤 奈津穂, 奥田 喜代司, 湯口 裕子, 山下 能毅, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 838 - 838, Japanese


• P3-52-9 初回完全摘出手術が困難である進行卵巣癌に対する腹腔鏡下手術の検討(Group 149 卵巣腫瘍・治療4,一般演題,公益社団法人日本産科婦人科学会第66回学術講演会)

  橋田 宗祐, 佐々木 浩, 梅嵜 乃斗香, 布出 実紗, 芦原 敬允, 中村 路彦, 田中 智人, 田中 良道, 恒遠 啓示, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 905 - 905, Japanese


• P3-50-4 卵巣粘液性腫瘍の術前正診率の向上を目指して(Group 147 卵巣腫瘍・診断1,一般演題,公益社団法人日本産科婦人科学会第66回学術講演会)

  寺田 信一, 寺井 義人, 平松 敦, 川口 浩史, 兪 史夏, 藤原 聡枝, 田中 良道, 田中 智人, 恒遠 啓示, 佐々木 浩, 金村 昌徳, 大道 正英

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 898 - 898, Japanese


• P1-5-7 子宮内膜症におけるドパミンD1,D2受容体の検討(Group 5 子宮内膜症・基礎1,一般演題,公益社団法人日本産科婦人科学会第66回学術講演会)

  八田 幸治, 山下 能毅, 小野 賀大, 山本 輝, 中村 容子, 吉田 陽子, 林 篤史, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 483 - 483, Japanese


• P1-3-3 不妊患者における子宮鏡下切除術の有用性(Group 3 不妊症1,一般演題,公益社団法人日本産科婦人科学会第66回学術講演会)

  中村 路彦, 田中 智人, 芦原 敬允, 前田 和也, 川口 浩史, 藤原 聡枝, 田中 良道, 林 篤史, 恒遠 啓示, 山下 能毅, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(2) (2), 474 - 474, Japanese


• 1. 妊娠中の婦人科良性腫瘍・悪性腫瘍 : 検診,診断,治療(クリニカルカンファレンス3-Subspecialtyを越えて(周産期・腫瘍)-,生涯研修プログラム,第66回日本産科婦人科学会学術講演会講演要旨)

  寺井 義人

  日本産科婦人科学会, 2014, 日本産科婦人科學會雜誌, 66(9) (9), 2089 - 2093, Japanese


• 子宮体がんとSERM (特集 ホルモン依存性悪性腫瘍 : 特徴と対処を考える) -- (子宮体がん)

  古形 祐平, 田辺 晃子, 寺井 義人

  金原出版, Sep. 2013, 産婦人科の実際, 62(9) (9), 1195 - 1200, Japanese


• 子宮体がんに対する腹腔鏡下手術 (今月の臨床 子宮体がん診療アップデート) -- (治療のトピックス)

  寺井 義人, 田中 智人, 大道 正英

  医学書院, May 2013, 臨床婦人科産科, 67(5) (5), 491 - 496, Japanese


• 腹腔鏡下生検で腹水細胞診陽性であった虫垂癌の一例

  小西博巳, 田中智人, 斉藤奈津穂, 藤原聡枝, 兪史夏, 田中良道, 恒遠啓示, 金村昌徳, 寺井義人, 大道正英

  2013, 日本臨床細胞学会雑誌, 52


• 茎捻転による急性腹症を伴った腫瘍内容液が13kgの巨大卵巣嚢腫の一例

  恒遠啓示, 寺井義人, 兪史夏, 徳重悠, 芦原敬允, 藤原聡枝, 田中智人, 田中良道, 林篤史, 金村昌徳, 山下能毅, 大道正英

  2013, 日本産科婦人科内視鏡学会雑誌, 29(Supplement 1) (Supplement 1)


• 婦人科癌における中等度催吐性化学療法TC療法に対する制吐剤3剤併用療法の効果検討

  藤原聡枝, 寺井義人, 川口浩史, 中村路彦, 兪史夏, 田中良道, 田中智人, 恒遠啓示, 金村昌徳, 大道正英

  2013, 日本癌治療学会学術集会(CD-ROM), 51st


• 若年子宮内膜癌・子宮内膜異型増殖症に対するMPA療法の治療成績

  田中良道, 寺井義人, 芦原敬允, 川口浩史, 前田和也, 劉昌恵, 中村路彦, 藤原聡枝, 兪史夏, 田中智人, 恒遠啓示, 金村昌徳, 大道正英

  2013, 日本癌治療学会学術集会(CD-ROM), 51st


• MRIで卵巣粘液性境界悪性腫瘍は診断できるか?

  寺田信一, 川口浩史, 野口智子, 徳重悠, 大門篤史, 村山結美, 前田和也, 芦原敬允, 劉昌恵, 中村路彦, 兪史夏, 藤原聡枝, 田中智人, 田中良道, 恒遠啓示, 金村昌徳, 寺井義人, 大道正英

  2013, 日本婦人科腫瘍学会雑誌, 31(3) (3)


• 婦人科癌における中等度催吐性化学療法TC療法に対する制吐剤3剤併用療法の効果検討

  藤原聡枝, 寺井義人, 太田沙緒里, 野口智子, 大門篤史, 芦原敬允, 劉昌徳, 前田和也, 徳重悠, 奥野勇輔, 布出実紗, 村山結美, 川口浩史, 中村路彦, 兪史夏, 田中良道, 田中智人, 恒遠啓示, 金村昌徳, 大道正英

  2013, 日本婦人科腫瘍学会雑誌, 31(3) (3)


• 若年子宮内膜癌・子宮内膜異型増殖症に対するMPA療法の治療成績

  田中良道, 寺井義人, 太田沙緒里, 寺田信一, 布出実紗, 村山結美, 徳重悠, 奥野勇輔, 劉昌恵, 前田和也, 芦原敬允, 川口浩史, 中村路彦, 兪史夏, 藤原聡枝, 関島龍治, 田中智人, 恒遠啓示, 金村昌徳, 大道正英

  2013, 日本婦人科腫瘍学会雑誌, 31(3) (3)


• 卵巣小細胞癌の1例

  丸岡寛, 藤原聡枝, 田中智人, 田中良道, 恒遠啓示, 金村昌徳, 寺井義人, 山田隆司, 辻求, 大道正英

  2013, 日本臨床細胞学会雑誌, 52


• プロメテウス 婦人科がん最新医療 子宮体がん 4.子宮体がんの手術療法(1)腹腔鏡下手術

  寺井義人, 田中智人, 藤原聡枝, YOO Saha, 田中良道, 佐々木浩, 恒遠啓示, 金村昌徳, 大道正英

  2013, 産婦人科の実際, 62(12) (12)


• 早期子宮体癌に対する腹腔鏡下手術

  田中智人, 寺井義人, 川口浩史, 中村路彦, 高井雅聡, 徳重悠, 野口智子, 大門篤史, 劉昌恵, 芦原敬允, 前田和也, 藤原聡枝, 兪史夏, 田中良道, 恒遠啓示, 金村昌徳, 大道正英

  2013, 日本婦人科腫瘍学会雑誌, 31(3) (3)


• 妊娠中の子宮頸部円錐切除術の留置点について

  芦原敬允, 田中良道, 前田和也, 中村路彦, 藤原聡枝, 兪史夏, 田中智人, 恒遠啓示, 金村昌徳, 寺井義人, 大道正英

  2013, 産婦人科の進歩, 65(4) (4)


• 当院における転移性卵巣腫瘍切除症例の検討

  芦原敬允, 佐野匠, 恒遠啓示, 川口浩史, 藤原聡枝, 兪史夏, 田中智人, 田中良道, 金村昌徳, 寺井義人, 大道正英

  2013, 日本癌治療学会学術集会(CD-ROM), 51st


• タモキシフェン内服後に発症した子宮癌肉腫の1例

  前沢早紀, 藤原聡枝, 兪史夏, 田中良道, 田中智人, 恒遠啓示, 金村昌徳, 寺井義人, 大道正英

  2013, 産婦人科の進歩, 65(2) (2)


• 白金製剤耐性卵巣癌におけるAktをターゲットとした分子標的薬としてのGemcitabineの機能解析

  川口浩史, 寺井義人, 寺田信一, 布出実紗, 野口智子, 大門篤史, 徳重悠, 前田和也, 劉昌恵, 芦原敬允, 中村路彦, 中村起代子, 高井雅聡, 兪史夏, 藤原聡枝, 田中智人, 田中良道, 恒遠啓示, 金村昌徳, 大道正英

  2013, 日本婦人科腫瘍学会雑誌, 31(3) (3)


• 先進医療に基づく腹腔鏡下子宮体癌手術

  田中智人, 寺井義人, 川口浩史, 中村路彦, 高井雅聡, 藤原聡枝, 愈史夏, 恒遠啓示, 金村昌徳, 大道正英

  2013, 産婦人科手術, (24) (24)


• 抗癌剤が及ぼす動脈硬化進展メカニズムの解析とフィブラートによる予防効果に関する検討

  渡辺綾子, 田辺晃子, 丸岡理紗, 川口浩史, 中村路彦, 中村起代子, 兪史夏, 藤原聡枝, 関島龍治, 田中智人, 田中良道, 恒遠啓示, 金村昌徳, 寺井義人, 大道正英

  2013, 日本婦人科腫瘍学会雑誌, 31(3) (3)


• 先進医療制度で始まった子宮体がんに対する腹腔鏡下手術

  寺井義人, 田中智人, 川口浩史, 高井雅聡, 兪史夏, 藤原聡枝, 中村路彦, 田中良道, 恒遠啓示, 金村昌徳, 山下能毅, 大道正英

  2013, 日本産科婦人科内視鏡学会雑誌, 29(Supplement 1) (Supplement 1)


• 子宮頸癌におけるCD24の発現意義

  田中智人, 寺井義人, 川口浩史, 中村路彦, 高井雅聡, 兪史夏, 藤原聡枝, 田中良道, 恒遠啓示, 田辺晃子, 金村昌徳, 大道正英

  2013, 日本癌治療学会学術集会(CD-ROM), 51st


• 子宮体がんに対する腹腔鏡下手術 (特集 婦人科がん手術の最前線) -- (子宮体がん)

  寺井 義人, 田中 智人, 佐々木 浩

  金原出版, Jan. 2013, 産婦人科の実際, 62(1) (1), 45 - 50, Japanese


• P1-1-7 婦人科悪性腫瘍に対する抗癌剤治療が動脈硬化へ及ぼす影響とフィブラートの予防効果について(Group 1 悪性腫瘍全般・基礎,一般演題,公益社団法人日本産科婦人科学会第65回学術講演会)

  渡辺 綾子, 田辺 晃子, 丸岡 理紗, 中村 起代子, 中村 路彦, 丸岡 寛, 中井 香奈, 斉藤 奈津穂, 澤田 雅美, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2013, 日本産科婦人科學會雜誌, 65(2) (2), 533 - 533, Japanese


• P3-2-5 卵巣癌における膜型エストロゲン受容体GPR30を介した転移メカニズムの解析(Group 107 卵巣腫瘍・基礎2,一般演題,公益社団法人日本産科婦人科学会第65回学術講演会)

  藤原 聡枝, 川口 浩史, 中村 路彦, 兪 史夏, 田中 智人, 田中 良道, 恒遠 啓示, 佐々木 浩, 金村 昌徳, 田辺 晃子, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2013, 日本産科婦人科學會雜誌, 65(2) (2), 861 - 861, Japanese


• P3-5-10 白金製剤耐性卵巣癌におけるAktをターゲットとした分子標的薬としてのGemcitabineの機能解析(Group 110 卵巣腫瘍・基礎5,一般演題,公益社団法人日本産科婦人科学会第65回学術講演会)

  川口 浩史, 寺井 義人, 恒遠 啓示, 佐々木 浩, 高井 雅聡, 藤原 聡枝, 兪 史夏, 田中 智人, 田中 良道, 金村 昌徳, 田辺 晃子, 大道 正英

  日本産科婦人科学会, 2013, 日本産科婦人科學會雜誌, 65(2) (2), 871 - 871, Japanese


• P3-4-3 卵巣癌におけるEMT現象の意義(Group 109 卵巣腫瘍・基礎4,一般演題,公益社団法人日本産科婦人科学会第65回学術講演会)

  高井 雅聡, 寺井 義人, 川口 浩史, 中村 路彦, 藤原 聡枝, 兪 史夏, 田中 良道, 田中 智人, 恒遠 啓示, 金村 昌徳, 田辺 晃子, 大道 正英

  日本産科婦人科学会, 2013, 日本産科婦人科學會雜誌, 65(2) (2), 866 - 866, Japanese


• P3-2-4 上皮間葉転換(EMT)を介した浸潤・転移の制御を目指して : CD24の機能解析(Group 107 卵巣腫瘍・基礎2,一般演題,公益社団法人日本産科婦人科学会第65回学術講演会)

  中村 起代子, 田中 良道, 川口 浩史, 高井 雅聡, 兪 史夏, 藤原 聡枝, 田中 智人, 恒遠 啓示, 田辺 晃子, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2013, 日本産科婦人科學會雜誌, 65(2) (2), 861 - 861, Japanese


• P3-8-1 卵巣腫瘍合併妊娠に対する妊娠時腹腔鏡下手術の検討(Group 113 卵巣腫瘍・腹腔鏡手術,一般演題,公益社団法人日本産科婦人科学会第65回学術講演会)

  藤山 史恵, 中村 嘉宏, 奥田 喜代司, 山下 能毅, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2013, 日本産科婦人科學會雜誌, 65(2) (2), 877 - 877, Japanese


• P3-35-1 子宮内膜症および卵巣嚢腫に対する各種細径腹腔鏡下手術の有用性(Group 140 腹腔鏡下手術3,一般演題,公益社団法人日本産科婦人科学会第65回学術講演会)

  斉藤 奈津穂, 奥田 喜代司, 中村 嘉宏, 藤山 史恵, 永易 洋子, 中井 里香, 樋口 容子, 山下 能毅, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2013, 日本産科婦人科學會雜誌, 65(2) (2), 958 - 958, Japanese


• P3-36-7 MRIで卵巣粘液性境界悪性腫瘍は診断できるか?(Group 141 卵巣腫瘍・診断,一般演題,公益社団法人日本産科婦人科学会第65回学術講演会)

  寺田 信一, 寺井 義人, 川口 浩史, 比嘉 涼子, 高井 雅聡, 兪 史夏, 藤原 聡枝, 田中 智人, 田中 良道, 恒遠 啓示, 金村 昌徳, 大道 正英

  日本産科婦人科学会, 2013, 日本産科婦人科學會雜誌, 65(2) (2), 962 - 962, Japanese


• P2-2-6 CINから初期子宮頸癌合併妊娠の管理について(Group 54 CIN・その他・診断・治療2,一般演題,公益社団法人日本産科婦人科学会第65回学術講演会)

  野口 智子, 田中 良道, 川口 浩史, 高井 雅聡, 中村 路彦, 兪 史夏, 藤原 聡枝, 田中 智人, 恒遠 啓示, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2013, 日本産科婦人科學會雜誌, 65(2) (2), 699 - 699, Japanese


• P1-22-3 早期子宮体癌に対する腹腔鏡手術(Group 22 子宮体部腫瘍・治療5,一般演題,公益社団法人日本産科婦人科学会第65回学術講演会)

  田中 智人, 寺井 義人, 川口 浩史, 中村 路彦, 高井 雅聡, 兪 史夏, 藤原 聡枝, 田中 良道, 恒遠 啓示, 佐々木 浩, 金村 昌徳, 大道 正英

  日本産科婦人科学会, 2013, 日本産科婦人科學會雜誌, 65(2) (2), 588 - 588, Japanese


• P1-29-4 当科における子宮内膜症に対する腹腔鏡下手術成績(Group 29 子宮内膜症・臨床4,一般演題,公益社団法人日本産科婦人科学会第65回学術講演会)

  徳重 悠, 山下 能毅, 林 篤史, 野口 智子, 寺田 信一, 斉藤 奈津穂, 澤田 雅美, 山本 輝, 吉田 陽子, 田中 智人, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2013, 日本産科婦人科學會雜誌, 65(2) (2), 607 - 607, Japanese


• 生殖免疫の立場から不妊症、不育症を議論する 子宮内膜症症例の黄体化顆粒膜細胞におけるアンドロゲン受容体とFSH受容体発現のエピジェネティック変化の検討(Expression and epigenetic change of the AR and FSHR genes in the granulosa cells of endometriosis patients)

  山下 能毅, 林 美佳, 林 篤史, 吉田 陽子, 川邉 紗智子, 林 正美, 寺井 義人, 亀谷 英輝, 大道 正英

  日本生殖免疫学会, Nov. 2012, Reproductive Immunology and Biology, 27(1-2) (1-2), 61 - 61, English


• 動注化学療後の神経温存広汎子宮全摘術における排尿機能の評価

  恒遠 啓示, 寺井 義人, 丸岡 寛, 川口 浩史, 中村 路彦, 高井 雅聡, 藤原 聡枝, 兪 史夏, 田中 良道, 田中 智人, 金村 昌徳, 稲元 輝生, 右梅 貴信, 東 治人, 大道 正英

  (一社)日本癌治療学会, Oct. 2012, 日本癌治療学会誌, 47(3) (3), 1783 - 1783, Japanese


• 妊娠子宮筋におけるプロゲステロン受容体とGPR30の筋収縮に対する発現意義

  加藤 壮介, 田辺 晃子, 澤田 雅美, 岡本 敦子, 鈴木 裕介, 湯口 裕子, 藤田 太輔, 荘園 ヘキ子, 林 正美, 寺井 義人, 亀谷 英輝, 大道 正英

  (公社)日本産科婦人科学会, Feb. 2012, 日本産科婦人科学会雑誌, 64(2) (2), 546 - 546, Japanese


• 骨盤内腫瘍に対する術前診断に苦慮し,腹腔鏡下手術で完全摘出術を行った尿膜管癌の1例

  兪史夏, 寺井義人, 中井香奈, 船内祐樹, 福田真美子, 川口浩史, 中村路彦, 高井雅聡, 藤原聡枝, 田中智人, 田中良道, 林篤史, 恒遠啓示, 金村昌徳, 山下能毅, 大道正英

  2012, 日本産科婦人科内視鏡学会雑誌, 28(1) (1)


• 妊娠中のCINから初期子宮頸癌の診断と治療

  田中良道, 川口浩史, 高井雅聡, 中村路彦, 兪史夏, 藤原聡枝, 田中智人, 恒遠啓示, 佐々木浩, 金村昌徳, 寺井義人, 大道正英

  2012, 日本癌治療学会学術集会(CD-ROM), 50th


• 進行卵巣癌NAC前の診断における腹腔鏡下手術の有用性について

  田中良道, 寺井義人, 寺田信一, 小西博巳, 丸岡寛, 斎藤奈津穂, 福田真実子, 川口浩史, 比嘉涼子, 中村路彦, 高井雅聡, 藤原聡枝, YU Saha, 田中智人, 恒遠啓示, 金村昌徳, 大道正英

  2012, 産婦人科の進歩, 64(3) (3)


• 腹腔鏡下手術で治療し得た腹膜妊娠の1例

  樋口容子, 林篤史, 吉田陽子, 山本輝, 川邉紗智子, 林美佳, 田中智人, 竹原幹雄, 山下能毅, 寺井義人, 大道正英

  2012, 日本産科婦人科内視鏡学会雑誌, 28(1) (1)


• 子宮頚部初期がんはどう治療するか

  寺井義人, 田中良道, 田中智人, 藤原聡枝, 兪史夏, 恒遠啓示, 川口浩史, 中村路彦, 金村昌徳, 大道正英

  2012, 日本婦人科腫瘍学会雑誌, 30(3) (3)


• 子宮頸部初期病変治療後のピットフォール

  田中良道, 寺井義人, 寺田信一, 丸岡寛, 小西博巳, 斎藤奈津穂, 永易洋子, 川口浩史, 比嘉涼子, 中村路彦, 兪史夏, 藤原聡枝, 田中智人, 恒遠啓示, 金村昌徳, 大道正英

  2012, 日本婦人科腫瘍学会雑誌, 30(3) (3)


• 術前に卵巣腫瘍と診断した脂肪成分を含む稀な充実性腫瘍の2例

  林篤史, 福田真実子, 山本輝, 樋口容子, 吉田陽子, 川邉紗智子, 林美佳, 藤原聡枝, 兪史夏, 田中良道, 田中智人, 山下能毅, 寺井義人, 山田隆司, 大道正英

  2012, 日本産科婦人科内視鏡学会雑誌, 28(1) (1)


• 血漿hCG低値の異所性妊娠に対して腹腔鏡下手術を施行した1例

  芦原敬允, 田中智人, 前田和也, 苅田正子, 岩井恵美, 神田隆善, 寺井義人, 大道正英

  2012, 日本産科婦人科内視鏡学会雑誌, 28(1) (1)


• 当科における卵巣境界悪性腫瘍に対する腹腔鏡手術の経験

  田中智人, 寺井義人, 川口浩史, 高井雅聡, 愈史夏, 藤原聡枝, 田中良道, 林篤史, 恒遠啓示, 金村昌徳, 山下能毅, 大道正英

  2012, 日本産科婦人科内視鏡学会雑誌, 28(1) (1)


• EBMに基づく子宮体がんに対する腹腔鏡下手術

  寺井義人, 田中智人, 丸岡寛, 小西博巳, 斉藤奈津穂, 比嘉涼子, 川口浩史, 高井雅聡, 兪史夏, 藤原聡枝, 中村路彦, 田中良道, 恒遠啓示, 金村昌徳, 大道正英

  2012, 日本産科婦人科内視鏡学会雑誌, 28(1) (1)


• 腹腔鏡下及び腹式筋腫核出後分娩の比較検討

  福田真実子, 林篤史, 船内祐樹, 樋口容子, 山本輝, 吉田陽子, 川辺紗智子, 鎌田美佳, 田中智人, 田中良道, 恒遠啓示, 山下能毅, 寺井義人, 大道正英

  2012, 日本産科婦人科内視鏡学会雑誌, 28(1) (1)


• 卵巣癌におけるエストロゲン受容体GPR30の上皮間葉転換(EMT)への関与

  藤原聡枝, 小西博巳, 斎藤奈津穂, 比嘉涼子, 高橋佳代, 川口浩史, 中村路彦, 高井雅聡, 兪史夏, 田中智人, 田中良道, 恒遠啓示, 金村昌徳, 寺井義人, 大道正英

  2012, 日本婦人科腫瘍学会雑誌, 30(3) (3)


• 婦人科癌の浸潤転移におけるEMT(Epithelial Mesenchymal Transition)の意義とEMT制御をターゲットとした新規治療の基礎的研究

  寺井義人, 田中良道, 川口浩史, 高井雅聡, 兪史夏, 藤原聡枝, 田中智人, 恒遠啓示, 金村昌徳, 田辺晃子, 大道正英

  2012, 日本婦人科腫瘍学会雑誌, 30(4) (4)


• 白金製剤耐性卵巣癌におけるAkt,ERKをターゲットとした分子標的薬としてのGemcitabineの機能解析

  川口浩史, 寺井義人, 恒遠啓示, 丸岡寛, 寺田信一, 永易洋子, 比嘉涼子, 中村路彦, 高井雅聡, 藤原聡枝, 兪史夏, 田中智人, 田中良道, 金村昌徳, 田辺晃子, 大道正英

  2012, 日本婦人科腫瘍学会雑誌, 30(3) (3)


• 卵巣癌の播種転移はEMT現象を反映する

  高井雅聡, 寺井義人, 川口浩史, 中村路彦, 藤原聡枝, 兪史夏, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, 金村昌徳, 田辺晃子, 大道正英

  2012, 日本癌治療学会学術集会(CD-ROM), 50th


• 0期子宮頸がんの治療 (婦人科がんの最新医学) -- (子宮頸がんの最新医学)

  寺井 義人

  日本評論社, 2012, からだの科学, (274) (274), 29 - 33, Japanese


• P1-11-8 婦人科悪性腫瘍手術及び術後化学療法の動脈硬化に及ぼす影響についての検討(Group11 婦人科腫瘍全般・症例3,一般演題,第64回日本産科婦人科学会学術講演会)

  渡辺 綾子, 田辺 晃子, 斎藤 奈津穂, 丸岡 理紗, 高井 雅聡, 中村 起代子, 兪 史夏, 田中 良道, 恒遠 啓示, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2012, 日本産科婦人科學會雜誌, 64(2) (2), 453 - 453, Japanese


• P1-11-11 有経女性の婦人科悪性腫瘍治療の骨密度に及ぽす影響について(Group11 婦人科腫瘍全般・症例3,一般演題,第64回日本産科婦人科学会学術講演会)

  中村 起代子, 田辺 晃子, 寺田 信一, 古形 祐平, 岡本 敦子, 丸岡 理紗, 渡辺 綾子, 高井 雅聡, 恒遠 啓示, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2012, 日本産科婦人科學會雜誌, 64(2) (2), 454 - 454, Japanese


• P2-3-4 白金製剤耐性卵巣癌におけるAktをターゲットとした分子標的薬としてのGemcitabineの機能解析(Group59 卵巣腫瘍・基礎3,一般演題)

  川口 浩史, 寺井 義人, 丸岡 寛, 岡本 敦子, 古形 祐平, 中村 路彦, 高井 雅聡, 藤原 聡枝, 兪 史夏, 恒遠 啓示, 金村 昌徳, 大道 正英

  日本産科婦人科学会, 2012, 日本産科婦人科學會雜誌, 64(2) (2), 598 - 598, Japanese


• P2-2-8 卵巣癌におけるEMT現象の指標となるE-cadherin,snail,slugの発現意義(Group58 卵巣腫瘍・基礎2,一般演題)

  高井 雅聡, 寺井 義人, 川口 浩史, 比嘉 涼子, 藤原 聡枝, 兪 史夏, 田中 良道, 佐々木 浩, 恒遠 啓示, 金村 昌徳, 田辺 晃子, 大道 正英

  日本産科婦人科学会, 2012, 日本産科婦人科學會雜誌, 64(2) (2), 595 - 595, Japanese


• P2-22-2 閉経後女性における卵巣機能とウィミンズヘルス(Group78 更年期・老年期1,一般演題)

  丸岡 理紗, 田辺 晃子, 広田 千賀, 中村 起代子, 高井 雅聡, 渡辺 綾子, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2012, 日本産科婦人科學會雜誌, 64(2) (2), 663 - 663, Japanese


• P2-11-2 傍大動脈リンパ節郭清におけるナビゲーションシステムを用いた卵巣動脈温存術とその応用(Group67 卵巣腫瘍・診断・予後1,一般演題)

  斎藤 奈津穂, 金村 昌徳, 田中 良道, 古形 祐平, 川口 浩史, 高井 雅聡, 兪 史夏, 藤原 聡枝, 佐々木 浩, 恒遠 啓示, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2012, 日本産科婦人科學會雜誌, 64(2) (2), 626 - 626, Japanese


• P3-7-8 安全な広汎子宮全摘出術を目指した術式の開発 : 子宮動脈2点pull up法(Group119 子宮頸部腫瘍・治療3)

  松波 早百合, 金村 昌徳, 兪 史夏, 吉村 真由美, 川口 浩史, 高井 雅聡, 藤原 聡枝, 田中 良道, 佐々木 浩, 恒遠 啓示, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2012, 日本産科婦人科學會雜誌, 64(2) (2), 779 - 779, Japanese


• P3-15-1 当院における子宮悪性腫瘍手術における腹腔鏡下手術(Group127 婦人科腫瘍・手術3)

  藤原 聡枝, 寺井 義人, 寺田 信一, 吉村 真由美, 比嘉 涼子, 樋口 容子, 中村 路彦, 兪 史夏, 田中 良道, 恒遠 啓示, 金村 昌徳, 大道 正英

  日本産科婦人科学会, 2012, 日本産科婦人科學會雜誌, 64(2) (2), 804 - 804, Japanese


• P1-7-1 子宮腺筋症癌化5症例における臨床病理学的検討(Group7 子宮体部腫瘍・診断・予後3,一般演題,第64回日本産科婦人科学会学術講演会)

  小西 博巳, 金村 昌徳, 兪 史夏, 比嘉 涼子, 川口 浩史, 高井 雅聡, 藤原 聡枝, 田中 良道, 佐々木 浩, 恒遠 啓示, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2012, 日本産科婦人科學會雜誌, 64(2) (2), 436 - 436, Japanese


• P1-8-4 子宮内膜癌のスクリーニング検査としての子宮鏡検査の有用性(Group8 子宮体部腫瘍・診断・治療1,一般演題,第64回日本産科婦人科学会学術講演会)

  恒遠 啓示, 寺井 義人, 寺田 信一, 川口 浩史, 神吉 一良, 藤原 聡枝, 兪 史夏, 関島 龍治, 田中 良道, 金村 昌徳, 猪木 千春, 大道 正英

  日本産科婦人科学会, 2012, 日本産科婦人科學會雜誌, 64(2) (2), 440 - 440, Japanese


• P1-2-8 子宮体癌におけるEMTのマーカーとしてのCD24の有用性(Group2 子宮体部腫瘍・基礎2,一般演題,第64回日本産科婦人科学会学術講演会)

  田中 良道, 寺井 義人, 斎藤 奈津穂, 川口 浩史, 中村 路彦, 兪 史夏, 藤原 聡枝, 佐々木 浩, 恒遠 啓示, 金村 昌徳, 田辺 晃子, 大道 正英

  日本産科婦人科学会, 2012, 日本産科婦人科學會雜誌, 64(2) (2), 420 - 420, Japanese


• 子宮頸部微小浸潤癌の治療戦略 (今月の臨床 子宮頸癌--予防と妊孕性温存のための治療戦略) -- (妊孕性温存のための治療戦略)

  寺井 義人, 金村 昌徳, 大道 正英

  医学書院, Oct. 2011, 臨床婦人科産科, 65(10) (10), 1239 - 1242, Japanese


• S状結腸癌の膣断端転移における細胞学的所見

  中村路彦, 田中智人, 金村昌徳, 寺井義人, 大道正英, 棟方哲

  2011, 日本臨床細胞学会雑誌, 50


• P2-13-14 進行子宮頸癌患者に対する術前化学療法(neoadjuvant chemotherapy:NAC)の治療成績(Group94 子宮頸部腫瘍・治療5,一般演題,第63回日本産科婦人科学会学術講演会)

  兪 史夏, 金村 昌徳, 吉村 真由美, 川口 浩史, 藤原 聡枝, 田中 良道, 関島 龍治, 恒遠 啓示, 佐々木 浩, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2011, 日本産科婦人科學會雜誌, 63(2) (2), 773 - 773, Japanese


• P2-14-16 エストロゲン受容体GPR30の子宮内膜癌における制御機構の解明(Group97 子宮体部悪性腫瘍・基礎1,一般演題,第63回日本産科婦人科学会学術講演会)

  佐々木 浩, 小西 博巳, 丸岡 寛, 兪 史夏, 藤原 聡枝, 関島 龍治, 田中 良道, 恒遠 啓示, 田辺 晃子, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2011, 日本産科婦人科學會雜誌, 63(2) (2), 784 - 784, Japanese


• P2-12-24 当科での骨盤神経温存広汎子宮全摘術の妥当性とurodynamics studyによる排尿機能の評価(Group92 子宮頸部腫瘍・治療4,一般演題,第63回日本産科婦人科学会学術講演会)

  恒遠 啓示, 寺井 義人, 丸岡 寛, 吉村 真由美, 川口 浩史, 鈴木 裕介, 藤原 聡枝, 田中 良道, 関島 龍治, 佐々木 浩, 金村 昌徳, 大道 正英

  日本産科婦人科学会, 2011, 日本産科婦人科學會雜誌, 63(2) (2), 768 - 768, Japanese


• P2-15-18 子宮体癌においてEMT(上皮間葉転換)は予後因子となりえるか?(Group100 子宮体部悪性腫瘍・診断・予後,一般演題,第63回日本産科婦人科学会学術講演会)

  田中 良道, 寺井 義人, 川口 浩史, 吉村 真由美, 兪 史夏, 藤原 聡枝, 関島 龍治, 佐々木 浩, 恒遠 啓示, 金村 昌徳, 田辺 晃子, 大道 正英

  日本産科婦人科学会, 2011, 日本産科婦人科學會雜誌, 63(2) (2), 795 - 795, Japanese


• P2-16-11 子宮体癌における脈管侵襲と臨床病理学的因子の検討(Group103 子宮体部悪性腫瘍・診断・手術2,一般演題,第63回日本産科婦人科学会学術講演会)

  川口 浩史, 恒遠 啓示, 寺井 義人, 丸岡 寛, 藤原 聡枝, 兪 史夏, 田中 良道, 関島 龍治, 佐々木 浩, 金村 昌徳, 山田 隆司, 大道 正英

  日本産科婦人科学会, 2011, 日本産科婦人科學會雜誌, 63(2) (2), 801 - 801, Japanese


• P2-20-23 卵巣癌におけるエストロゲン受容体GPR30およびER・PRの発現と臨床病理学的意義(Group114 悪性卵巣腫瘍・基礎4,一般演題,第63回日本産科婦人科学会学術講演会)

  藤原 聡枝, 寺井 義人, 田辺 晃子, 川口 浩史, 芦原 敬允, 古形 祐平, 兪 史夏, 田中 良道, 関島 龍治, 佐々木 浩, 金村 昌徳, 大道 正英

  日本産科婦人科学会, 2011, 日本産科婦人科學會雜誌, 63(2) (2), 837 - 837, Japanese


• P2-21-10 転移性卵巣粘液性腺癌の術前・術中診断のポイント : 2症例からの考察(Group115 悪性卵巣腫瘍・症例1,一般演題,第63回日本産科婦人科学会学術講演会)

  吉村 真由美, 田中 良道, 古形 祐平, 劉 昌恵, 藤原 聡枝, 兪 史夏, 関島 龍治, 佐々木 浩, 恒遠 啓示, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2011, 日本産科婦人科學會雜誌, 63(2) (2), 842 - 842, Japanese


• P2-21-9 子宮内膜性嚢胞癌化を示唆する画像所見の変化について : 3症例からの考察(Group115 悪性卵巣腫瘍・症例1,一般演題,第63回日本産科婦人科学会学術講演会)

  田吹 邦雄, 田中 良道, 吉村 真由美, 古形 祐平, 芦原 敬允, 西尾 桂奈, 兪 史夏, 藤原 聡枝, 佐々木 浩, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2011, 日本産科婦人科學會雜誌, 63(2) (2), 842 - 842, Japanese


• P2-24-26 婦人科悪性腫瘍における傍大動脈リンパ節郭清術の必要性と安全性(Group126 婦人科悪性腫瘍・手術合併症2,一般演題,第63回日本産科婦人科学会学術講演会)

  岡本 敦子, 田中 良道, 劉 昌恵, 川口 浩史, 兪 史夏, 藤原 聡枝, 関島 龍治, 佐々木 浩, 恒遠 啓示, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2011, 日本産科婦人科學會雜誌, 63(2) (2), 877 - 877, Japanese


• 神経温存広汎子宮全摘術における排尿機能の評価

  恒遠 啓示, 川口 浩史, 寺井 義人, 二村 元, 芦原 敬允, 藤岡 聡枝, 田中 良道, 関島 龍治, 佐々木 浩, 金村 昌徳, 田邊 晃子, 右梅 貴信, 東 治人, 勝岡 洋治, 大道 正英

  (一社)日本癌治療学会, Sep. 2010, 日本癌治療学会誌, 45(2) (2), 1043 - 1043, Japanese


• 卵巣がん治療ガイドライン2010年版について 卵巣がん治療ガイドライン 上皮性悪性卵巣腫瘍(概論・卵巣癌の治療・手術療法)

  大道 正英, 田畑 務, 寺井 義人, 八幡 哲郎, 渡利 英道, 岡本 愛光, 佐藤 豊実

  (公社)日本婦人科腫瘍学会, Jun. 2010, 日本婦人科腫瘍学会雑誌, 28(3) (3), 279 - 279, Japanese


• 産婦人科教室 私たちの教室紹介(SERIES 3)大阪医科大学産婦人科学教室

  寺井 義人, 大道 正英

  診断と治療社, Mar. 2010, 産科と婦人科, 77(3) (3), 328 - 330, Japanese


• 若年性卵巣腫瘍茎捻転の1例

  田中智人, 岩井恵美, 神田隆善, 山下能毅, 寺井義人, 奥田喜代司, 大道正英

  2010, 日本産科婦人科内視鏡学会雑誌, 26(1) (1)


• P1-263 婦人科悪性腫瘍手術における傍大動脈リンパ節郭清は合併症を増加させるか?(Group32 婦人科腫瘍その他2,一般演題,第62回日本産科婦人科学会学術講演会)

  芦原 敬允, 田中 良道, 藤岡 聡枝, 前田 和也, 佐野 匠, 高橋 良明, 関島 龍治, 佐々木 浩, 恒遠 啓示, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2010, 日本産科婦人科學會雜誌, 62(2) (2), 436 - 436, Japanese


• P3-207 卵巣癌における抗癌剤感受性に基づいた新規molecular markerとしてのNFκBの意義(Group124 卵巣腫瘍9,一般演題,第62回日本産科婦人科学会学術講演会)

  佐々木 浩, 寺井 義人, 高橋 良明, 芦原 敬允, 古形 祐平, 田吹 邦雄, 藤岡 聡枝, 関島 龍治, 恒遠 啓示, 金村 昌徳, 田辺 晃子, 大道 正英

  日本産科婦人科学会, 2010, 日本産科婦人科學會雜誌, 62(2) (2), 693 - 693, Japanese


• P3-143 婦人科悪性腫瘍に対して深部静脈血栓症(DVT)・肺血栓塞栓症(PE)のスクリーニング検査は必要か : 致死性PEを防ぐために(Group116 婦人科腫瘍血栓症2,一般演題,第62回日本産科婦人科学会学術講演会)

  中村 路彦, 金村 昌徳, 宮本 良子, 樋口 容子, 山本 輝, 藤岡 聡枝, 田中 良道, 関島 龍治, 恒遠 啓示, 佐々木 浩, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2010, 日本産科婦人科學會雜誌, 62(2) (2), 672 - 672, Japanese


• P1-216 卵巣癌におけるGPR30とEGFRの免疫組織化学的検討(Group26 卵巣腫瘍2,一般演題,第62回日本産科婦人科学会学術講演会)

  藤岡 聡枝, 寺井 義人, 田中 良道, 樋口 容子, 芦原 敬允, 古形 祐平, 関島 龍治, 佐々木 浩, 恒遠 啓示, 金村 昌徳, 田辺 晃子, 大道 正英

  日本産科婦人科学会, 2010, 日本産科婦人科學會雜誌, 62(2) (2), 420 - 420, Japanese


• P1-211 卵巣癌におけるEGFR遺伝子変異とその下流シグナル分子の発現解析(Group26 卵巣腫瘍2,一般演題,第62回日本産科婦人科学会学術講演会)

  田中 良道, 寺井 義人, 藤岡 聡枝, 中村 路彦, 高橋 良明, 芦原 敬允, 関島 龍治, 佐々木 浩, 恒遠 啓示, 金村 昌徳, 田辺 晃子, 大道 正英

  日本産科婦人科学会, 2010, 日本産科婦人科學會雜誌, 62(2) (2), 419 - 419, Japanese


• P2-156 子宮頸癌術後治療におけるCCRTの合併症と抗癌化学療法の可能性について(Group63 子宮頸部悪性腫瘍4,一般演題,第62回日本産科婦人科学会学術講演会)

  恒遠 啓示, 寺井 義人, 中村 路彦, 加藤 壮介, 川辺 紗智子, 藤岡 聡枝, 田中 良道, 関島 龍治, 佐々木 浩, 金村 昌徳, 大道 正英

  日本産科婦人科学会, 2010, 日本産科婦人科學會雜誌, 62(2) (2), 516 - 516, Japanese


• 子宮頸部微小浸潤扁平上皮癌の子宮温存の適応と限界 (特集 QOLを考慮した婦人科がん治療) -- (妊孕能温存)

  寺井 義人, 佐々木 浩, 恒遠 啓示

  医学書院, Dec. 2009, 臨床婦人科産科, 63(12) (12), 1486 - 1489, Japanese


• The management of the microinvasive carcinoma of the cervix

  寺井 義人, 大道 正英

  日本臨床社, Aug. 2009, Japanese journal of clinical medicine, 67, 210 - 214, Japanese


• エストロゲン・プロゲステロン合剤内服後に生じた子宮内外同時妊娠の1例

  田中智人, 山下能毅, 岩井恵美, 神田隆善, 加藤俊, 加藤壮介, 寺井義人, 大道正英

  2009, 日本産科婦人科内視鏡学会雑誌, 25(1) (1)


• 経頚管的吸引法とMTXにより治療した子宮間質部妊娠の1例

  田中智人, 山下能毅, 岩井恵美, 神田隆善, 加藤壮介, 寺井義人, 大道正英

  2009, 日本産科婦人科内視鏡学会雑誌, 25(1) (1)


• P3-100 CTよるリンパ節転移の画像診断の有用性(Group88 画像診断,一般演題,第61回日本産科婦人科学会学術講演会)

  恒遠 啓示, 寺井 義人, 川辺 紗智子, 加藤 壮介, 藤岡 聡枝, 田中 良道, 佐々木 浩, 金村 昌徳, 田辺 晃子, 大道 正英

  日本産科婦人科学会, 2009, 日本産科婦人科學會雜誌, 61(2) (2), 701 - 701, Japanese


• P3-27 当科における子宮内膜間質肉腫症例の検討(Group79 子宮体部悪性腫瘍8,一般演題,第61回日本産科婦人科学会学術講演会)

  高井 雅聡, 金村 昌徳, 藤岡 聡枝, 田中 良道, 関島 龍治, 佐々木 浩, 恒遠 啓示, 田辺 晃子, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2009, 日本産科婦人科學會雜誌, 61(2) (2), 676 - 676, Japanese


• P1-39 子宮内膜癌に対するmedroxyprogesterone acetate(MPA)の作用機序(Group6 子宮体部悪性腫瘍4,一般演題,第61回日本産科婦人科学会学術講演会)

  佐々木 浩, 寺井 義人, 田中 良道, 関島 龍治, 恒遠 啓示, 藤岡 聡枝, 金村 昌徳, 田辺 晃子, 大道 正英

  日本産科婦人科学会, 2009, 日本産科婦人科學會雜誌, 61(2) (2), 459 - 459, Japanese


• Maintenance Treatment with Bevacizumab Prolongs Survival in an In vivo Ovarian Cancer Model

  Seiji Mabuchi, Yoshito Terai, Kenichiro Morishige, Akiko Tanabe-Kimura, Hiroshi Sasaki, Masanori Kanemura, Satoshi Tsunetoh, Yoshimichi Tanaka, Masahiro Sakata, Robert A. Burger, Tadashi Kimura, Masahide Ohmichi

  Dec. 2008, CLINICAL CANCER RESEARCH, 14(23) (23), 7781 - 7789, English


• 卵巣癌における抗癌剤耐性の克服 (今月の臨床 卵巣癌診療の最新情報) -- (卵巣癌治療の将来展望)

  寺井 義人, 大道 正英

  医学書院, Oct. 2008, 臨床婦人科産科, 62(10) (10), 1332 - 1337, Japanese


• P-147 子宮体部原発神経内分泌腫瘍の1例(子宮体部(6),グローバル時代の細胞診,第47回日本臨床細胞学会秋期大会)

  藤岡 聡枝, 田中 良道, 恒遠 啓示, 竹原 幹雄, 金村 昌徳, 寺井 義人, 山田 隆司, 辻 求, 岡田 仁克

  特定非営利活動法人日本臨床細胞学会, 22 Sep. 2008, 日本臨床細胞学会雑誌, 47(2) (2), 553 - 553, Japanese


• P-140 子宮体部癌肉腫の1症例(子宮体部(4),グローバル時代の細胞診,第47回日本臨床細胞学会秋期大会)

  田中 良道, 恒遠 啓示, 佐々木 浩, 竹原 幹雄, 金村 昌徳, 寺井 義人, 山田 隆司, 岡田 仁克, 芝山 雄老, 大道 正英

  特定非営利活動法人日本臨床細胞学会, 22 Sep. 2008, 日本臨床細胞学会雑誌, 47(2) (2), 549 - 549, Japanese


• 産婦人科医が行う乳がん検診 (特集 婦人科がんの検診--その効果と問題点)

  篠原 智子, 寺井 義人, 大道 正英

  金原出版, Sep. 2008, 産婦人科の実際, 57(9) (9), 1411 - 1419, Japanese


• 卵巣癌における分子標的治療の展望は? (今月の臨床 産婦人科臨床の難題を解く--私はこうしている) -- (婦人科癌治療 卵巣癌)

  寺井 義人, 大道 正英

  医学書院, Apr. 2008, 臨床婦人科産科, 62(4) (4), 643 - 649, Japanese


• A case report of abdominal wall endometriosis

  田中智人, 寺井義人, 加藤壮介, 加藤俊, 大道正英

  2008, 産婦人科の進歩, 60(4) (4)


• P2-17 局所進行子宮頸がん患者に対する術前化学療法CPT-11 iv/CDDP BOAI第II相試験(Group36 子宮頸部悪性腫瘍6,一般演題,第60回日本産科婦人科学会学術講演会)

  金村 昌徳, 寺井 義人, 竹原 幹雄, 恒遠 啓示, 佐々木 浩, 田中 良道, 大道 正英

  日本産科婦人科学会, 2008, 日本産科婦人科學會雜誌, 60(2) (2), 619 - 619, Japanese


• P2-242 Topoisomerase 1 inhibitorであるtopotecanのCDDP耐性解除機構(Group62 感染症3,一般演題,第60回日本産科婦人科学会学術講演会)

  佐々木 浩, 寺井 義人, 金村 昌徳, 竹原 幹雄, 恒遠 啓示, 田中 良道, 田辺 晃子, 大道 正英

  日本産科婦人科学会, 2008, 日本産科婦人科學會雜誌, 60(2) (2), 694 - 694, Japanese


• P1-201 topoisomerase I inhibitorであるtopotecanはin vivoにおいてCDDP耐性を解除するか?(Group23 卵巣腫瘍1,一般演題,第60回日本産科婦人科学会学術講演会)

  恒遠 啓示, 寺井 義人, 金村 昌徳, 竹原 幹緒, 佐々木 浩, 田中 良道, 田辺 晃子, 大道 正英

  日本産科婦人科学会, 2008, 日本産科婦人科學會雜誌, 60(2) (2), 563 - 563, Japanese


• P3-116 大動脈周囲リンパ節郭清術の合併症軽減に向けた工夫(Group80 卵巣腫瘍8,一般演題,第60回日本産科婦人科学会学術講演会)

  寺井 義人, 金村 昌徳, 竹原 幹雄, 悟遠 啓示, 佐々木 浩, 田中 良道, 大道 正英

  日本産科婦人科学会, 2008, 日本産科婦人科學會雜誌, 60(2) (2), 769 - 769, Japanese


• 260 短期間で進行した子宮体部明細胞腺癌の一症例(子宮体部2(9),一般演題,第46回日本臨床細胞学会秋期大会)

  田中 良道, 恒遠 啓示, 佐々木 浩, 安田 勝行, 竹原 幹雄, 金村 昌徳, 寺井 義人, 山田 隆司, 辻 求, 大道 正英

  特定非営利活動法人日本臨床細胞学会, 22 Sep. 2007, 日本臨床細胞学会雑誌, 46(2) (2), 541 - 541, Japanese


• 子宮体癌とSERM (今月の臨床 子宮体癌の最新知見--専門医のために)

  大道 正英, 寺井 義人, 森嶌 祥子

  医学書院, Feb. 2007, 臨床婦人科産科, 61(2) (2), 112 - 117, Japanese


• P1-91 局所進行子宮頸がん患者に対する術前化学療法CPT-11 iv/CDDP BOAI第II相試験(Group7 子宮頸部腫瘍7,一般演題,第59回日本産科婦人科学会学術講演会)

  金村 昌徳, 寺井 義人, 西山 浩司, 安田 勝行, 山口 裕之, 竹原 幹雄, 恒遠 啓示, 荘園 ヘキ子, 大道 正英

  日本産科婦人科学会, 2007, 日本産科婦人科學會雜誌, 59(2) (2), 379 - 379, Japanese


• P2-76 定期的子宮鏡検査で管理した子宮内膜癌と子宮内膜異型増殖症に対するMPA療法(Group111 子宮体部腫瘍10,一般演題,第59回日本産科婦人科学会学術講演会)

  安田 勝行, 猪木 千春, 恒遠 啓示, 荘園 へキ子, 西山 浩司, 山口 裕之, 竹原 幹雄, 金村 昌徳, 寺井 義人, 大道 正英

  日本産科婦人科学会, 2007, 日本産科婦人科學會雜誌, 59(2) (2), 589 - 589, Japanese

• 腹腔鏡下婦人科悪性腫瘍におけるセンチネルリンパ節ナビゲーション手術

  田中智人, TERAI YOSHITO, 大道正英

  第31回日本内視鏡外科学会, Dec. 2018, Japanese, 福岡, Domestic conference

  Public symposium


• 当科で行っている腹腔鏡下神経温存広汎子宮全摘出術の実際

  TERAI YOSHITO, 田中智人, 大道正英

  第31回日本内視鏡外科学会, Dec. 2018, Japanese, 福岡, Domestic conference

  Public symposium


• 子宮体癌に対する腹腔鏡下手術適応拡大とさらなる低侵襲化を目指して

  TERAI YOSHITO, 田中智人, 大道正英

  第31回日本内視鏡外科学会, Dec. 2018, Japanese, 福岡, Domestic conference

  Public symposium


• 当院におけるHBOC診療体制の現況

  丸岡 寛, 田中良道, 寺田信一, 古形祐平, 藤原聡枝, 田中智人, 恒遠啓示, 佐々木浩, TERAI YOSHITO, 大道正英

  第139回近畿産科婦人科学会総会ならびに学術集会, Oct. 2018, Japanese, 大阪, Domestic conference

  Oral presentation


• プラチナ感受性再発卵巣癌へのベバシズマブの有用性とプラチナフリー期間への関与

  藤原聡枝, 寺田信一, 古形祐平, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, TERAI YOSHITO, 大道正英

  第56回日本癌治療学会, Oct. 2018, Japanese, 横浜, Domestic conference

  Oral presentation


• 腹腔鏡下子宮体癌手術の現状と展望

  TERAI YOSHITO

  第60回日本婦人科腫瘍学会, Sep. 2018, Japanese, 京都, Domestic conference

  Public symposium


• 化学療法無効の子宮内膜間質肉腫（high grade）に対してパゾパニブが効果を示した1 例

  丸岡 寛, 田中良道, 寺田信一, 古形祐平, 藤原聡枝, 田中智人, 恒遠啓示, 佐々木浩, TERAI YOSHITO, 大道正英

  第60回日本婦人科腫瘍学会, Sep. 2018, Japanese, 京都, Domestic conference

  Oral presentation


• 腹膜透析中の子宮内膜増殖症患者に対して腹腔鏡下子宮全摘出術を施行した一例

  宮本瞬輔, 寺田信一, 小西博巳, 古形祐平, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, TERAI YOSHITO, 大道正英

  第58回日本産科婦人科内視鏡学会, Aug. 2018, Japanese, 島根, Domestic conference

  Oral presentation


• 腹腔鏡手術を施行した妊娠合併未熟奇形腫の一例 －当院の未熟奇形腫後方視的検討を加えて

  上田尚子, 大瀧瑠璃, 宮本瞬輔, 寺田信一, 中村奈津穂, 穀内香奈, 古形祐平, 田中良道, 田中智人, 恒遠啓示, TERAI YOSHITO, 大道正英

  第58回日本産科婦人科内視鏡学会, Aug. 2018, Japanese, 島根, Domestic conference

  Oral presentation


• 腹腔鏡下手術を施行した卵巣境界悪性腫瘍の予後の検討

  村山結美, 上田尚子, 中村奈津穂, 小西博巳, 穀内香奈, 古形祐平, 藤原聡枝, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, TERAI YOSHITO, 大道正英

  第58回日本産科婦人科内視鏡学会, Aug. 2018, Japanese, 島根, Domestic conference

  Oral presentation


• 腹腔鏡下手術で診断された卵巣原発偽粘液腫の1例

  丸岡 寛, 上田尚子, 宮本瞬輔, 小西博巳, 村山結美, 多賀紗也香, 古形祐平, 藤原聡枝, 田中智人, 佐々木浩, 恒遠啓示, TERAI YOSHITO, 大道正英

  第58回日本産科婦人科内視鏡学会, Aug. 2018, Japanese, 島根, Domestic conference

  Oral presentation


• 当院における腹腔鏡下子宮体癌手術の治療成績

  藤原聡枝, 寺田信一, 古形祐平, 芦原敬允, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, TERAI YOSHITO, 大道正英

  第58回日本産科婦人科内視鏡学会, Aug. 2018, Japanese, 島根, Domestic conference

  Oral presentation


• 当院における腹腔鏡下広汎子宮全摘出術と開腹広汎子宮全摘出術の検討

  田中良道, TERAI YOSHITO, 村山結美, 寺田信一, 古形祐平, 藤原聡枝, 田中智人, 佐々木浩, 恒遠啓示, 大道正英

  第58回日本産科婦人科内視鏡学会, Aug. 2018, Japanese, 島根, Domestic conference

  Oral presentation


• 当院での子宮内膜症性嚢胞に対する腹腔鏡下手術後の再発予防について

  古形祐平, 大瀧瑠璃, 田中サキ, 布出実紗, 中村奈津穂, 小西博巳, 穀内香奈, 田中智人, 恒遠啓示, TERAI YOSHITO, 大道正英

  第58回日本産科婦人科内視鏡学会, Aug. 2018, Japanese, 島根, Domestic conference

  Oral presentation


• 第一助手を育てれば、術者が育つ

  恒遠啓示, TERAI YOSHITO, 田中サキ, 寺田信一, 小西博巳, 村山結美, 穀内香奈, 古形祐平, 田中智人, 大道正英

  第58回日本産科婦人科内視鏡学会, Aug. 2018, Japanese, 島根, Domestic conference

  Oral presentation


• 子宮内膜症合併不妊症における腹腔鏡下手術についての検討

  小西博巳, 恒遠啓示, 寺田信一, 古形祐平, 田中良道, 田中智人, 佐々木浩, 林 正美, TERAI YOSHITO, 大道正英

  第58回日本産科婦人科内視鏡学会, Aug. 2018, Japanese, 島根, Domestic conference

  Oral presentation


• 再発悪性腫瘍に対して、腹腔鏡下手術で腫瘍摘出しえた2例

  寺田信一, TERAI YOSHITO, 上田尚子, 宮本瞬輔, 村山結美, 多賀紗也香, 古形祐平, 藤原聡枝, 田中良道, 田中智人, 恒遠啓示, 大道正英

  第58回日本産科婦人科内視鏡学会, Aug. 2018, Japanese, 島根, Domestic conference

  Oral presentation


• 境界悪性Brenner腫瘍の1例

  大瀧瑠璃, 田中良道, 土橋裕允, 橋田宗祐, 丸岡 寛, 古形祐平, 芦原敬允, 藤原聡枝, 田中智人, 恒遠啓示, 佐々木浩, TERAI YOSHITO, 大道正英

  第138回近畿産科婦人科学会総会ならびに学術集会, Jun. 2018, Japanese, 大阪, Domestic conference

  Oral presentation


• 13歳で手術を要した子宮筋腫の1例

  橋田宗祐, 寺田信一, 古形祐平, 芦原敬允, 藤原聡枝, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, TERAI YOSHITO, 大道正英

  第138回近畿産科婦人科学会総会ならびに学術集会, Jun. 2018, Japanese, 大阪, Domestic conference

  Oral presentation


• 卵巣境界悪性腫瘍・悪性腫瘍合併妊娠に対する腹腔鏡下手術の検討

  寺田信一, 越田裕一郎, 大門篤史, 布出実紗, 小西博巳, 中村奈津穂, 芦原敬允, 田中智人, 恒遠啓示, 佐々木浩, TERAI YOSHITO, 大道正英

  第70回日本産科婦人科学会, May 2018, Japanese, 仙台, Domestic conference

  Oral presentation


• 分娩後1年以内の子宮頸部円錐切除症例の後方視的解析 子宮頸部円錐切除術の実態調査に関する小委員会(婦人科腫瘍委員会）報告

  田中良道, TERAI YOSHITO, 古形祐平, 大道正英, 池田仁惠, 三上幹男, 榎本隆之, 小林陽一, 永瀬 智, 横山正俊, 片渕秀隆

  第70回日本産科婦人科学会, May 2018, Japanese, 仙台, Domestic conference

  Oral presentation


• 腹腔鏡下婦人科悪性腫瘍におけるアドスプレーの有用性

  TERAI YOSHITO

  第70回日本産科婦人科学会, May 2018, Japanese, 仙台, Domestic conference

  Public discourse


• 妊娠中子宮頸部円錐切除症例の後方視的解析 子宮頸部円錐切除術の実態調査に関する小委員会(婦人科腫瘍委員会）報告

  古形祐平, TERAI YOSHITO, 田中良道, 大道正英, 池田仁惠, 三上幹男, 榎本隆之, 小林陽一, 永瀬 智, 横山正俊, 片渕秀隆

  第70回日本産科婦人科学会, May 2018, Japanese, 仙台, Domestic conference

  Oral presentation


• 早期子宮頸癌患者に対するリンパ節転移の診断には、FDG PET/CTとセンチネルリンパ節生検術のどちらが有用か？

  土橋裕允, 田中智人, 兪 史夏, 恒遠啓示, 前田和也, 芦原敬允, 寺田信一, 丸岡 寛, 橋田宗祐, 田中良道, TERAI YOSHITO, 大道正英

  第70回日本産科婦人科学会, May 2018, Japanese, 仙台, Domestic conference

  Oral presentation


• 進行・再発子宮頸癌における Bevacizumab 併用療法の有用性について

  芦原敬允, 飯藤宰士, 橋田宗祐, 寺田信一, 丸岡 寛, 古形祐平, 前田和也, 藤原聡枝, 田中智人, 恒遠啓示, TERAI YOSHITO, 大道正英

  第70回日本産科婦人科学会, May 2018, Japanese, 仙台, Domestic conference

  Oral presentation


• 子宮内膜症合併卵巣がんと脂質異常症は関連しているか？

  佐々木浩, 丸岡 寛, 大瀧瑠璃, 飯藤宰士, 越田裕一郎, 中村真由美, 太田沙緒里, 穀内香奈, 多賀紗也香, 寺田信一, TERAI YOSHITO, 大道正英

  第70回日本産科婦人科学会, May 2018, Japanese, 仙台, Domestic conference

  Oral presentation


• 子宮体癌の骨盤リンパ節転移の予測においてのPET-CTとセンチネルリンパ節生検の有用性の比較

  橋田宗祐, 田中智人, 大瀧瑠璃, 丸岡 寛, 古形祐平, 前田和也, 芦原敬允, 兪 史夏, 藤原聡枝, 佐々木浩, TERAI YOSHITO, 大道正英

  第70回日本産科婦人科学会, May 2018, Japanese, 仙台, Domestic conference

  Oral presentation


• 佐々木浩、丸岡 寛、大瀧瑠璃、飯藤宰士、越田裕一郎、中村真由美、太田沙緒里、穀内香奈、多賀紗也香、寺田信一、寺井義人、大道正英

  前田和也, 藤田太輔, 橋田宗祐, 寺田信一, 丸岡 寛, 芦原敬允, 田中良道, 田中智人, 恒遠啓示, 佐々木浩, TERAI YOSHITO, 大道正英

  第70回日本産科婦人科学会, May 2018, Japanese, 仙台, Domestic conference

  Oral presentation


• Neoadjuvant intraarterial chemotherapy using an original four-lumen doubleballoon catheter for locally advanced uterine cervical cancer

  Tanaka T, Tsuchihashi H, Terada S, Nunoda M, Konishi H, Nakamura N, Ashihara K, Maeda K, Yoo S, Sasaki H, TERAI YOSHITO, Ohmichi M

  第70回日本産科婦人科学会, May 2018, English, 仙台, Domestic conference

  Public discourse


• 70歳以上の高齢者における腹腔鏡下手術の安全性の検討

  丸岡 寛, 藤原聡枝, 寺田信一, 中村奈津穂, 古形祐平, 前田和也, 田中良道, 田中智人, 佐々木浩, 恒遠啓示, TERAI YOSHITO, 大道正英

  第70回日本産科婦人科学会, May 2018, Japanese, 仙台, Domestic conference

  Oral presentation


• 膀胱、尿管損傷を回避するために我々が気を付けること ビデオを見ながら

  TERAI YOSHITO

  2017年度 腹腔鏡下子宮悪性腫瘍手術セミナー, Feb. 2018, Japanese, 大阪, Domestic conference

  Oral presentation


• 婦人科腫瘍医が目指す腹腔鏡下手術

  TERAI YOSHITO

  2017年度 腹腔鏡下子宮悪性腫瘍手術セミナー, Feb. 2018, Japanese, 大阪, Domestic conference

  Public discourse


• 子宮腺筋症に対するSequential療法の検討

  古形祐平, TERAI YOSHITO, 中村奈津穂, 大道正英

  第39回日本エンドメトリオーシス学会学術講演会, Jan. 2018, Japanese, 京都, Domestic conference

  Oral presentation