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NOMURA TadashiUniversity Hospital / Plastic Surgery & Aesthetic SurgeryAssociate Professor
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■ Paper- BACKGROUND: In patients with slow-flow vascular malformations (SFVMs) including venous malformations (VM), lymphatic malformations (LM) or Klippel-Trenaunay Syndrome (KTS), somatic gain-of-function mutations in genes encoding phosphatidyl inositol 3-kinase alpha (PI3Kα, gene name PIK3CA) have been identified. A phase 2 study was conducted with the patients to assess the efficacy and safety of ART-001 (serabelisib), an orally available selective PI3Kα inhibitor. METHODS: This is a multicenter, randomized, double-blind, proof-of-concept, phase 2 trial. Eligible participants were patients aged 2 years and older, diagnosed either with VM, LM or KTS. Participants were administered either 50 or 100 mg of ART-001 for 24 weeks. The primary endpoint was the response rate defined as the proportion of participants who achieved ≥ 20% reduction in lesion volume at week 24. Secondary endpoints include safety, pharmacokinetics, pain, and quality of life scores. RESULTS: Thirty-five patients (median age: 14 years old; VM, n = 17, KTS, n = 13 and LM, n = 5) were randomly assigned and received treatment (50 mg, n = 17 and 100 mg, n = 18). ART-001 showed a response rate: 29.4% (95% confidence interval 10.3-56.0%) at 50 mg and 33.3% (13.3-59.0%) at 100 mg. Mean lesion volume reductions at 50 mg and 100 mg were - 2.3% (95% CI - 14.3 to 9.6%) and - 12.6% (- 25.3 to 0.06%), respectively. No drug-related serious adverse events were observed. Treatment-emergent adverse events were generally mild to moderate and transient. Pharmacokinetic profiles were similar between pediatric and adolescent/adult patients except for lower Ctrough levels in pediatric patients. CONCLUSION: ART-001 was effective and well-tolerated in patients with SFVMs. These results support the further development of ART-001 in SFVMs and other PIK3CA-related overgrowth syndromes to confirm clinical benefits and long-term safety. TRIAL REGISTRATION: Japan Registry of Clinical Trial, jRCT2071210027. Registered May 25 2021, https://jrct.niph.go.jp/en-latest-detail/jRCT2071210027.Feb. 2025, Orphanet journal of rare diseases, 20(1) (1), 64 - 64, English, International magazineScientific journal
- Jan. 2025, Journal of Clinical MedicineScientific journal
- OBJECTIVE: To evaluate the effect and safety of sclerotherapy in patients with difficult-to-resect venous malformations treated with ethanolamine oleate. DESIGN AND SETTING: This investigator-initiated clinical trial employed a multicenter, single-arm design and was conducted in Japan. PATIENTS: Overall, 44 patients with difficult-to-resect venous malformations were categorized into two cohorts: 22 patients with cystic-type malformations and 22 patients with diffuse-type malformations, including children (<15 years old). INTERVENTIONS: Adult patients received injections of 5% ethanolamine oleate solution, double diluted with contrast or normal saline, with a maximum dose of 0.4 mL/kg. The same method of administration was used for children (<15 years old). The maximum volume of the prepared solution in one treatment was 30 mL. EVALUATION METHODS: Treatment effect was assessed by evaluating the difference in lesion volume using magnetic resonance imaging as a primary endpoint and differences in pain using a visual analog scale as a key secondary endpoint. RESULTS: Among the 45 patients who consented, one was excluded owing to potential intracranial involvement of venous malformations during screening. Regarding the primary outcome, 26 of 44 patients (59.1%, 95% confidence interval: 44.41-72.31%) achieved ≥ 20% reduction in malformation volume, with 16 patients having cystic lesions (72.7%, 51.85-86.85%) and 10 patients having diffuse lesions (45.5%, 26.92-65.34%). Both cohorts showed significant improvement in self-reported pain scores associated with lesions 3 months post-sclerotherapy. No death or serious adverse events occurred. Hemoglobinuria was observed in 23 patients (52%), a known drug-related adverse event. Prompt initiation of haptoglobin therapy led to full recovery within a month for these patients. CONCLUSIONS: Ethanolamine oleate shows potential as a therapeutic sclerosing agent for patients with difficult-to-resect venous malformations.2025, PloS one, 20(1) (1), e0303130, English, International magazineScientific journal
- Dec. 2024, Journal of reconstructive microsurgery, English, International magazineScientific journal
- INTRODUCTION: Arteriovenous malformations (AVMs) of facial bones are rare conditions. These lesions can cause aesthetic challenges, pain, impact on gums and teeth, facial asymmetry, and life-threatening bleeding. PRESENTATION OF THE CASE: This report described a case involving the resection of AVMs within the maxilla following preoperative embolization and sclerotherapy by using an ultrasonic bone aspirator (Sonopet®, Stryker, Kalamazoo, MI, USA) and a radiofrequency bipolar sealer (Aquamantys™, Medtronic, Minneapolis, MN, USA). The AVMs and deformed bone were resected en bloc through repeated cutting and hemostasis, preserving the maxillary crown and maintaining the maxillary structure by treating only the affected bone. DISCUSSION: Reducing inflow during surgery and controlling intraoperative bleeding requires thorough planning. Preoperative embolization and sclerotherapy can reduce inflow to the tumor, and appropriate surgical devices enable the resection of arteriovenous malformations within the maxilla. CONCLUSION: The method presented in this report is a viable treatment option because it allows for selective bone removal, thus leading to the preservation of crowns and maxillary contour.Nov. 2024, International journal of surgery case reports, 124, 110450 - 110450, English, International magazineScientific journal
- Orbital lymphatic malformations significantly impair visual function, with inflammation contributing to corneal dryness and diplopia due to exophthalmos. Disease progression may lead to blindness, and in severe cases, exenteration may be required. We treated two symptomatic cases of adult orbital slow-flow vascular malformations with oral sirolimus. Although the patients maintained good visual acuity before treatment, prominent exophthalmos posed a substantial risk to visual function. After medication, eyeball proptosis improved significantly in all cases, with magnetic resonance imaging volumetry analysis showing a reduction of 28.5% to 82.1%. This treatment demonstrated minimal side effects and may serve as an initial therapeutic option.Oct. 2024, Cureus, 16(10) (10), e71478, English, International magazineScientific journal
- In cases of lacrimal gland carcinoma requiring surgical excision of the orbital contents, skull base, and surrounding bones, definitive blockage of the cranial cavity and reconstruction of the anterior skull base with irradiation-acceptable tissue (for possible subsequent radiotherapy) is necessary. However, considerations for quality of life, including cosmetic aspects, such as artificial eye placement and contour morphology, make reconstruction challenging. In three cases of advanced lacrimal gland carcinoma, we performed a reconstruction surgery following an en bloc resection of the orbital contents and lateral orbital bones. A rectus abdominis flap was used, considering both function and morphology. This flap, characterized by reliable anatomical structure and good blood flow, adequately filled the three-dimensional dead space. In our case, the flap fully survived, and no complications such as cerebrospinal fluid leakage or meningitis were observed. Six months after surgery, the flap volume was 31.7-73.3% of its initial size. Considering potential flap shrinkage in the future, it was deemed beneficial to use a slightly excessive volume.Sep. 2024, Cureus, 16(9) (9), e69310, English, International magazineScientific journal
- Bowen's disease (BD), also known as squamous cell carcinoma (SCC) in situ, is a precancerous skin condition that can potentially progress to invasive tumors. Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine tumor typically found in sun-exposed areas of elderly Caucasians. The coexistence of BD and MCC is extremely rare, particularly when MCC is located in subcutaneous tissue rather than its typical epidermal or dermal layers. This case report presents an unusual instance of BD coexisting with subcutaneous MCC on the dorsum of the hand in an elderly Japanese male. An 87-year-old Japanese male with over 30 years of sun exposure presented with a progressively enlarging red tumor on the dorsum of his left hand. A biopsy confirmed BD, and the tumor was excised with a 5 mm margin followed by skin grafting. Histopathological examination revealed subcutaneous MCC along with BD, with MCC cells forming small nests in the dermal papillary layer. Immunohistochemistry showed positive staining for synaptophysin and CK20 in a perinuclear dot pattern, confirming the MCC diagnosis. Given the patient's advanced age and the absence of positive surgical margins, a watch-and-wait approach was adopted. The patient has been under close outpatient monitoring, and no recurrence has been observed after six months. This case highlights the rarity of subcutaneous MCC coexisting with BD, with only a few reported cases of such coexistence. The unusual subcutaneous presentation and the presence of multiple micro-nodules instead of large atypical cell clusters suggest an early-stage MCC beneath BD. The pathogenesis of this coexistence remains unclear but raises important questions regarding the relationship between sun exposure and viral factors like Merkel cell polyomavirus (MCPyV), which was not tested in this case. The findings underscore the need for comprehensive diagnostic evaluation when encountering complex or atypical skin lesions. This report emphasizes the rarity of subcutaneous MCC coexisting with BD and underscores the importance of comprehensive diagnostic assessment in unusual cases. Further research is warranted to better understand the underlying mechanisms and to guide optimal management strategies for such rare and challenging presentations.Sep. 2024, Cureus, 16(9) (9), e69114, English, International magazineScientific journal
- Myxomas, when they manifest in the paranasal sinuses and/or maxillae of infants, are classified as sinonasal myxomas (SNMs). We present a case of SNM in the maxilla of a 15-month-old infant. Following the initial surgical intervention, the patient unfortunately experienced a recurrence of the condition. However, a subsequent surgery employing marginal excision was performed, and since then, no further recurrence has been reported. SNM exhibits consistent clinical features and histological characteristics that are distinct from those of odontogenic myxomas. Furthermore, in this case, immunohistochemical staining was positive for β-catenin, whereas odontogenic myxomas are generally negative for β-catenin staining. Another study reported that SNMs share genetic mutations with desmoid tumors, which are not observed in odontogenic myxomas. This suggests that this entity is distinct from odontogenic myxomas, leading us to propose that it may indeed represent a separate disease entity. This fact may lead to the reclassification of the disease and, ultimately, to changes in treatment strategies.Corresponding, Aug. 2024, Cureus, 16(8) (8), e65933, English, International magazine[Refereed]Scientific journal
- Background Since the larynx and pharynx are vital for respiration, swallowing, and speech, chemoradiotherapy (CRT) has been widely applied for T3 hypopharyngeal cancer (HPC) as an organ-preserving treatment. However, CRT can lead to severe late adverse events such as dysphagia and aspiration pneumonia, especially in patients who have difficulty swallowing and/or aspiration at the time of initial diagnosis. Patients and methods Between 2012 and 2020, 86 patients with T3 HPC treated with curative intent at Kobe University Hospital were included in this study. The average age was 69 years old, ranging from 43 to 89. Diseases were classified as Stage III in 29 patients, Stage IVA in 52 patients, and Stage IVB in five patients. Thirty-five (41%) patients were treated by CRT, and 51 (59%) patients were treated by surgery. Patients were followed up for at least two years, and the follow-up period ranged from four to 128 months (median: 45 months). Results Three-year progression-free survival (PFS) rates of patients treated by CRT and patients treated by surgery were 56.2% and 60.3%, respectively. Three-year disease-specific survival (DSS) rates of patients treated by CRT and surgically treated patients were 79.0% vs. 70.8%, respectively. Three-year overall survival (OS) rates of patients treated by CRT and surgically treated patients were 64.5% and 69.0%, respectively. Of note, a significant difference was observed between three-year DSS and three-year PFS (79.0% vs. 56.2%, p = 0.0014) in the patients treated by CRT but not in the patients treated by surgery. Conclusions No significant differences were observed between the PFS, DSS, and OS rates of patients treated by CRT and those of surgically treated patients. Locoregional recurrences after CRT were significantly successfully salvaged by surgical intervention. These results suggest that CRT can be applied as an alternative to surgery without reducing survival, especially for patients without severe clinical symptoms. Meticulous follow-up is mandatory for early detection of recurrence to salvage by surgery and for the management of late adverse events.Jun. 2024, Cureus, 16(6) (6), e62553, English, International magazine[Refereed]Scientific journal
- Background: The natural history of venous malformation (VM) and Klippel-Trenaunay Syndrome (KTS) has not been quantitatively studied. To obtain benchmarks to guide designing clinical trials to assess safety and efficacy of novel drug candidates, the clinical course of the patients was followed for 6 months. Methods and Results: This is a multicenter prospective observational study evaluating the change rate in lesion volume from baseline with magnetic resonance images, as the primary endpoint. In addition, disease severities, performance status (PS), pain visual analog scale (VAS) score, quality of life (QoL), infections, and coagulation markers were also evaluated. Thirty-four patients (VM = 17, KTS = 17, 1-53 of age; median 15.9 years) with measurable lesion volume were analyzed. There was no statistically significant difference in the lesion volume between baseline and day 180, and the mean change rate (standard deviation) was 1.06 (0.28). There were no baseline characteristics that affected the change in lesion volume over 6 months. However, there were patients who showed more than 20% volume change and it was suggested that the lesion volume was largely impacted by local infection. There were no statistically significant changes in pain VAS score, severity, PS, QoL score, D-dimer, and platelet count over 6 months within all patients analyzed. Conclusion: The results showed the representative natural course of VM and KTS for a 6-month period with objective change of lesion volume and other factors, suggesting that it is scientifically reasonable to conduct a Phase 2 proof-of-concept study without a placebo arm, using the results of this study as the control. Clinical Trial Registration: NCT04285723, NCT04589650.Feb. 2024, Lymphatic research and biology, 22(1) (1), 27 - 36, English, International magazine[Refereed]Scientific journal
- We report a case of a second free jejunal transfer to treat metastasis in the mesenteric lymph node of the first jejunal flap. A 73-year-old man underwent total pharyngolaryngectomy, bilateral neck dissection, and free jejunal transfer for recurrent hypopharyngeal cancer [left pyriform sinus, pT2N0, moderately differentiated squamous cell carcinoma (SCC)] after radiotherapy. Seven years post-surgery, he underwent transoral videolaryngoscopic surgery for oropharyngeal cancer (soft palate, pT1N0, well-differentiated SCC). Ten years after the first jejunal transfer, metastasis was found in the mesenteric lymph node surrounding the jejunal flap's vascular pedicle. Under general anesthesia, resection of the first jejunum including the affected lymph node, and second jejunal transfer were performed. Lymph node pathological examination revealed poorly differentiated SCC, compatible with pharyngeal cancer metastasis. After neck dissection and jejunal flap transfer, lymphatic collateral pathways toward the flap's mesenteric lymph node might form. Possibly, hypopharyngeal or oropharyngeal cancer metastasized via this pathway.Dec. 2023, Journal of surgical case reports, 2023(12) (12), rjad686, English, International magazine[Refereed]
- 克誠堂出版(株), Nov. 2023, 形成外科, 66(11) (11), 1283 - 1287, Japanese[Refereed]
- Aug. 2023, The Journal of craniofacial surgery, 34(8) (8), 2410 - 2412, EnglishA Clinical Study of Histopathological and Clinical Image Changes After Sclerotherapy of Lip Venous Malformations.[Refereed]
- This study aimed to elucidate the vasodilatory effects and cytotoxicity of various vasodilators used as antispasmodic agents during microsurgical anastomosis. Rat smooth muscle cells (RSMCs) and human coronary artery endothelial cells (HCAECs) were used to investigate the physiological concentrations and cytotoxicity of various vasodilators (lidocaine, papaverine, nitroglycerin, phentolamine, and orciprenaline). Using a wire myograph system, we determined the vasodilatory effects of each drug in rat abdominal aortic sections at the concentration resulting in maximal vasodilation as well as at the surrounding concentrations 10 min after administration. Maximal vasodilation effect 10 min after administration was achieved at the following concentrations: lidocaine, 35 mM; papaverine, 0.18 mM; nitroglycerin, 0.022 mM; phentolamine, 0.11 mM; olprinone, 0.004 mM. The IC50 for lidocaine, papaverine, and nitroglycerin was measured in rat abdominal aortic sections, as well as in RSMCs after 30 min and in HCAECs after 10 min. Phentolamine and olprinone showed no cytotoxicity towards RSMCs or HCAECs. The concentrations of the various drugs required to achieve vasodilation were lower than the reported clinical concentrations. Lidocaine, papaverine, and nitroglycerin showed cytotoxicity, even at lower concentrations than those reported clinically. Phentolamine and olprinone show antispasmodic effects without cytotoxicity, making them useful candidates for local administration as antispasmodics.Jun. 2023, International journal of molecular sciences, 24(13) (13), English, International magazineScientific journal
- (一社)日本乳房オンコプラスティックサージャリー学会, Mar. 2023, Oncoplastic Breast Surgery, 8(1) (1), 32 - 35, Japanese
- UNLABELLED: Abdominal incisional hernia is a complication of the rectus abdominis myocutaneous (RAMC) flap harvest. This study aimed to compare the incidence of abdominal incisional hernia and donor-site closure time between absorbable barbed continuous (ABC) and non-absorbable non-barbed interrupted (nAnBI) methods. METHODS: This study included 145 patients who underwent free RAMC flap reconstruction after head and neck cancer surgery at Kobe University Hospital between January 2012 and March 2020. The nAnBI method was selected between January 2012 and August 2016, and the ABC method was selected between September 2016 and March 2020. The incidence of abdominal incisional hernia and the average time required for donor-site closure were compared between the two groups. RESULTS: Of the 145 patients surveyed, 116 (57 and 59 in the nAnBI and ABC groups, respectively) were followed-up for at least 90 days after the surgery. The incidence rates of abdominal incisional hernia were 0% and 5.1% (n = 3) in the nAnBI and ABC groups, respectively, with no significant differences (p = 0.244). The average donor-site closure times were 127.6 and 111.3 minutes in the nAnBI and ABC groups, respectively, with no significant differences (p = 0.122). CONCLUSIONS: No significant differences in the incidence of abdominal incisional hernia and donor-site closure time were observed between the nAnBI and ABC groups. However, there was a tendency for increased hernia occurrence and shorter wound closure time in the ABC group. A randomized prospective multicenter study is warranted to validate our findings of the ABC method.Jan. 2023, Plastic and reconstructive surgery. Global open, 11(1) (1), e4742, English, International magazineScientific journal
- Japan Neurosurgical Society, Dec. 2022, NMC Case Report Journal, 9, 243 - 247Scientific journal
- INTRODUCTION: Post-sternotomy surgical site infection (SSI) is a serious complication of cardiovascular surgery. Here, we proposed a new clinical classification and reconstructive strategy for this condition. METHODS: A retrospective study based on medical records was performed on 100 consecutive cases requiring wound management by plastic surgeons for post-sternotomy SSI at Kobe University Hospital between January 2009 and December 2021. We classified 100 cases into four categories according to the anatomical invasiveness of the infection (type 1, superficial SSI; type 2, sternal osteomyelitis; type 3, mediastinitis; and type 4, aortic graft infection). The standard treatment plan comprised initial debridement, negative pressure wound therapy with continuous irrigation, and reconstructive surgery. Reconstructive methods and their outcomes (in-hospital mortality rate, follow-up period, and infection recurrence rate) were investigated for each SSI category. RESULTS: There were nine SSI cases in type 1, 28 in type 2, 25 in type 3, and 38 in type 4. The pectoralis major (PM) muscle advancement flap was mainly selected in types 1 and 2 (100 and 70.4%, respectively), while the omental flap or latissimus dorsi (LD) myocutaneous flaps were mainly selected in types 3 and 4 (77.3 and 81.8%, respectively) for reconstructive surgery. The in-hospital mortality rates for types 1, 2, 3, 4 were 44.4, 3.6, 12.0, and 15.8%, respectively. The mean follow-up periods for types 1, 2, 3, 4 were 542.8, 1514.5, 1154.5, and 831.1 days, respectively. Infection recurrence rates for types 1, 2, 3, 4 were 0, 11.5, 13.3, and 19.2%, respectively. All of these recurrent cases, except for 4 cases of type 4 that required surgical intervention, were treated with conservative wound management. CONCLUSION: A volume-rich flap (omental or LD flap) was required to fill the dead space after debridement in mediastinitis (type 3) or aortic graft infection (type 4), whereas superficial SSI (type 1) or sternal osteomyelitis (type 2) received a less-invasive flap (PM muscle advancement flap). Our new classification method was based on the anatomical invasiveness of the infection, providing both a simple and easy diagnosis and definitive treatment strategy.Dec. 2022, Regenerative therapy, 21, 519 - 526, English, International magazineScientific journal
- We report a case of palliative surgery in a 73-year-old patient with metastatic plantar sarcoma. The patient underwent resection and irradiation of an undifferentiated spindle cell sarcoma in the right plantar region. The wound was not closed and systemic metastases were observed. The chief complaint of the patient on his first visit to our department was difficulty walking due to pain in the right plantar region. Since we were unsuccessful in relieving the pain with conservative treatment, we decided to perform a palliative free tissue transfer to the right plantar. The surgery was successful, the skin ulcer healed, and the pain was relieved after the surgery. When performing palliative surgery, more detailed preoperative management and planning are necessary to achieve a successful outcome. The selection of the flaps according to the local lesion and metastatic lesions and changes in the local hemodynamics should be considered when planning.Oct. 2022, Cureus, 14(10) (10), e30488, English, International magazine
- This study aimed to analyze the Hess area ratio (HAR%) in cases of blowout fracture treated in our department and clarify the outline of eye movement disorders in blowout fractures. Patients who underwent surgery for orbital blowout fractures in our department were included. Fracture locations were classified into 5 types (A, outside floor; B, C, anterior and posterior floor; and D, E, anterior and posterior medial wall). The HAR% was compared before and after surgery in eligible cases. The relationship between the fracture location and preoperative HAR% was investigated using multiple regression analysis. The study involved 85 patients. Hess area ratio was higher postoperatively than preoperatively (70.75 ± 18.26 versus 90.06 ± 13.99, P < 0.01). The postoperative HAR% tended to be higher when the iliac bones were compared to other materials; however, this difference was not significant (90.73 ± 12.91 versus 80.30 ± 17.81, P = 0.178). Fracture locations C and E significantly contributed to the prediction of HAR% as negative regression coefficients (P = 0.024 and 0.013, respectively). The posterior fracture area on both the orbital floor and medial wall contributed to the decrease in preoperative HAR%. This observation indicates that the reconstruction of the posterior region is extremely crucial.Jun. 2022, The Journal of craniofacial surgery, 33(4) (4), 1042 - 1045, English, International magazineScientific journal
- (株)全日本病院出版会, Feb. 2022, PEPARS, (182) (182), 35 - 41, Japanese【遊離皮弁をきれいに仕上げる-私の工夫-】遊離皮弁を用いた頭蓋再建
- We introduce a treatment that combines the cross-leg free flap with the Masquelet technique and describe two cases using this method for bone and soft tissue reconstruction. Both patients were successfully treated and ambulatory. This novel method can be safely performed using the delay technique, indocyanine-green angiography and near-infrared spectroscopy.2022, Case reports in plastic surgery & hand surgery, 9(1) (1), 99 - 104, English, International magazine
- 2022, Eplasty, 22, ic1, English, International magazineA Case of a Rare Branching Pattern in the Carotid Artery.
- (一社)日本頭蓋顎顔面外科学会, Nov. 2021, 日本頭蓋顎顔面外科学会学術集会プログラム・抄録集, 39回, 77 - 77, Japanese同種顔面移植-我が国の現況と展望- 頭蓋顎顔面外科、頭頸部再建外科、美容外科の協働によるCSTを活用した同種顔面移植手技の習得と開発
- We herein report three cases of mature teratomas with pineal gland differentiation, which is a less recognized phenomenon. Case 1 was a 6-year-old male with a neck mass, Case 2 was a 23-year-old female with a retroperitoneal mass, and Case 3 was a 45-year-old female with a retroperitoneal mass. Each case showed the typical macroscopic and histological findings of mature teratoma, such as solid and cystic lesions mainly lined with a mature squamous epithelium. All cases also showed glial differentiation. Small foci of lobulated cell nests were detected in the center of or adjacent to mature glial tissue. Cells had a clear to pale eosinophilic cytoplasm with small round nuclei. Immunohistochemically, cells were positive for synaptophysin, neurofilament protein with a perivascular "club-shaped swelling" pattern, and cone-rod homeobox protein. To the best of our knowledge, this is the first report of pineal gland differentiation arising in mature teratoma, which may be easily overlooked or misdiagnosed as somatic-type tumors, particularly neuroendocrine tumors. To avoid overtreatment, pathologists need to be aware that pineal gland differentiation may occur in mature teratomas.Nov. 2021, Pathology international, 71(11) (11), 771 - 776, English, International magazine
- INTRODUCTION: We hypothesized that hybrid artificial nerves might overcome the limitations of a nerve conduit by isolating nerve fascicles from autologous nerves. Nerve sacrifice during harvest, a drawback of conventional autologous nerve transplantation, may be reduced by the hot dog method. The hot dog method (based on the morphology of hybrid artificial nerves) adds nerve conduits to autologous nerve fascicles. METHODS: Forty-eight rats with a 10-mm sciatic nerve defect were divided into six groups (n = 8 per group) according to the neural reconstruction method: autologous nerve transplantation, the hot dog method, nerve conduit, nerve fascicle transplantation, sham control, and nerve fascicle isolation were classified as Groups I, II, III, IV, V, and VI, respectively. The sciatic nerve function was assessed in these groups, a histological evaluation was performed, and statistical analyses were conducted based on these data. RESULTS: Group III (nerve conduit) and Group IV (nerve fascicle transplantation) showed the lowest functional and axonal regenerative effects, followed by Group II (hot dog method) and Group I (autologous nerve transplantation). Group VI (nerve fascicle isolation) tended to achieve better recovery in motor function and axonal regeneration than Group I (autologous nerve transplantation). CONCLUSIONS: The hot dog method is simple, safe, and easy to execute. This method can serve as a new neural reconstruction method that uses artificial nerves.Oct. 2021, The International journal of artificial organs, 44(10) (10), 711 - 717, English, International magazineScientific journal
- Corresponding, (一社)日本形成外科学会, Sep. 2021, 日本形成外科学会会誌, 41(9) (9), 522 - 527, JapaneseSturge-Weber症候群に伴う口腔内化膿性肉芽腫の治療経験:術前塞栓療法と外科的切除の併用[Refereed]
- 克誠堂出版(株), Jul. 2021, 形成外科, 64(7) (7), 809 - 816, Japanese
- Corresponding, (一社)日本形成外科学会, Jul. 2021, 日本形成外科学会会誌, 41(7) (7), 371 - 377, Japanese外陰部に発生したaggressive angiomyxomaの1例
- A congenital cheek fistula is a rare malformation in the buccal area. Here, we report the case of a congenital cheek fistula in a 50-year-old woman who visited our clinic with complaints of swelling and pain in her left cheek. Physical examination revealed a small hole in the left corner of the mouth present since birth. She had no other congenital malformations in the maxillofacial region such as an accessory ear and cleft lip. Manual compression of the cheek mass induced serous discharge from the hole. Magnetic resonance imaging (MRI) showed a cystic lesion in the left cheek and a fistula within the orbicularis oris muscle that opened into the small hole. After immediate incision and drainage of the cyst, both the cyst and fistula were surgically resected. The cystic lesion was completely delineated from the boundary of the parotid gland. The orbicularis oris muscle was partially incised to remove the fistula and the surrounding scar tissue. Histopathological examination of the resected specimen revealed a cavity consisting of epithelium inside the fistula. The postoperative course was insignificant. No recurrence of the cyst was observed six months postoperatively. The operative and pathological findings demonstrated that the ectoderm-derived epithelial tissue was enclosed by the mesoderm-derived muscle tissue. The mixture of different germ layer-derived tissues suggested that the fistula was a type of congenital transverse facial cleft induced by malfusion of the mandibular and maxillary prominences during embryonic development. The differential diagnoses of the congenital cheek fistula included orocutaneous fistulas and salivary fistulas. MRI was useful in delineating the border between the lesion and the surrounding tissue.Jun. 2021, Cureus, 13(6) (6), e15657, English, International magazine
- Lead, (NPO)日本レーザー医学会, Apr. 2021, 日本レーザー医学会誌, 42(1) (1), 18 - 22, Japanese[Refereed][Invited]
- 日本シミュレーション外科学会, Mar. 2021, 日本シミュレーション外科学会会誌, 28(1) (1), 19 - 21, Japanese有茎腹直筋皮弁による骨盤底再建の3次元的解析 骨盤内最短経路
- Corresponding, Mar. 2021, JOURNAL OF VASCULAR ANOMALIES, 2(1) (1), e003, EnglishA Rare Case of Infantile Hemangioma Requiring Ear Reconstruction[Refereed]Scientific journal
- INTRODUCTION: Limited literature exists regarding the positional relationship between the pedicled-rectus abdominis myocutaneous (p-RAMC) flap and residual pelvic organs post posterior pelvic exenteration (PPE). PRESENTATION OF CASE: Four patients underwent PPE and reconstruction with a p-RAMC flap. After harvesting the p-RAMC flap with the deep inferior epigastric artery and veins as the vascular pedicle, the intra-pelvic shortest pathway of the flap was created. We dissected the subcutaneous tissues of the flap donor site toward the perineal defect along the inner wall of the pelvis. The pubic origin of the rectus abdominis muscle was preserved. A three-dimensional model was constructed using an image processing software. The vascular pedicle ran almost linearly along the inner wall of the pelvis. The muscle belly was placed on the pelvic floor through the posterior wall of the urinary bladder which filled the dead space of the resected area. All flaps survived without significant complications. DISCUSSION: Assigning the cranial side of the flap to the perineum and caudal side to the pelvic floor could reduce postoperative intrapelvic complications. By preserving the pubic origin of the rectus abdominis muscle, a shock absorber of the pedicle of the flap was created, preventing over-traction of the flap while passing through the intrapelvic pathway. CONCLUSION: A p-RAMC flap via intra-pelvic shortest pathway is an ideal reconstructive method for large skin defect in perineal area after PPE.Feb. 2021, International journal of surgery case reports, 80, 105629 - 105629, English, International magazineScientific journal
- BACKGROUND: Intraoperative vasospasm during reconstructive microvascular surgery is often unpredictable and may lead to devastating flap loss. Therefore, various vasodilators are used in reconstructive microsurgery to prevent and relieve vasospasm. Lidocaine is a vasodilator commonly used in microvascular surgery. Although many reports have described its in vitro and in vivo concentration-dependent vasodilatory effects, limited studies have examined the pharmacological effects of lidocaine on blood vessels in terms of persistence and titer. METHODS: In this study, the vasodilatory effect of lidocaine was examined by using the wire myograph system. Abdominal aortas were harvested from female rats, sliced into rings of 1-mm thickness, and mounted in the wire myograph system. Next, 10, 5, 2, and 1% lidocaine solutions were applied to the artery, and the change in vasodilation force, persistence of the force, and time required to reach equilibrium were measured. RESULTS: The vasodilatory effect was confirmed in all groups following lidocaine treatment. Although strong vasodilation was observed in the 10% lidocaine group, it was accompanied by irreversible degeneration of the artery. Vasodilation in the 1% lidocaine group was weaker than that in the other groups 500 seconds after lidocaine addition (p < 0.05). Between the 5 and 2% lidocaine groups, 5% lidocaine showed a stronger vasodilatory effect 400 to 600 seconds after lidocaine addition (p < 0.01); however, there was no significant difference in these groups after 700 seconds. Additionally, there was no difference in the time required for the relaxation force to reach equilibrium among the 5, 2, and 1% lidocaine groups. CONCLUSION: Although our study confirmed the dose-dependent vasodilatory effect of lidocaine, 5% lidocaine showed the best vasodilatory effect and continuity with minimal irreversible changes in the arterial tissue.Jan. 2021, Journal of reconstructive microsurgery, 37(6) (6), 541 - 550, English, International magazineScientific journal
- Corresponding, (一社)日本形成外科学会, Nov. 2020, 日本形成外科学会会誌, 40(11) (11), 612 - 618, Japanese播種性血管内凝固症候群を合併した青色ゴムまり様母斑症候群の治療経験[Refereed]
- PURPOSE: This study aimed to examine the usefulness of treating orbital blowout fracture using a customized rigid carrier. MATERIAL AND METHODS: Patients who underwent surgery for orbital blowout fractures in our department from April 2016 to March 2019 were recruited in the study. We molded a rigid thermoplastic material into the same shape as the reconstruction material according to the 3D model and transplanted it into the orbital space along with the reconstruction material. We assessed Hertel exophthalmometry, awareness of diplopia, and the Hess area ratio (HAR%). RESULTS: We performed this procedure in 15 patients with blowout fractures. Reconstruction materials used were iliac bone, absorbable plates, and titanium mesh in 12, 2, and 1 patient, respectively. None of the patients showed a difference of more than 2 mm on Hertel exophthalmometry. Only one patient had diplopia after surgery. The average preoperative and postoperative HAR% were 83.1 and 90.6, respectively. HAR% was more than 85% in 6 of 7 postoperative cases. CONCLUSIONS: This method can be applied for surgery using various reconstructive materials and can be a useful method, especially in patients with a wide range of orbital bone defects.Elsevier BV, Nov. 2020, Journal of Cranio-Maxillofacial Surgery, 48(11) (11), 1052 - 1056, English, International magazineScientific journal
- (一社)日本外科学会, Aug. 2020, 日本外科学会定期学術集会抄録集, 120回, SF - 7, Japanese食道癌術後の膵頭部癌に対しmicrosurgeryによる右胃大網動静脈再建を行い胃管温存膵頭十二指腸切除を施行した2例
- Correct anatomical reconstruction of the orbital wall for function and cosmesis is important; however, this is difficult because of the structure's complexity. The authors aimed to analyze and classify orbital morphology from computed tomography (CT) images and examine the relationship between orbital morphology and eyelid morphology in the Japanese population. CT images of 60 men (right side, 29; left side, 31) and 44 women (each side, 22) were included. The lengths of the orbital medial wall and floor in the coronal plane at the anterior, middle, and posterior planes of the orbit; angle between them; simotic index; and the thickness of upper eyelid were measured. Additionally, the presence or absence of double eyelids was evaluated. Non-paired Student's t test and Pearson correlation coefficient test were used for analysis. Orbital morphology was symmetrical on both sides, and men had a larger orbit than women. Orbital morphology was classified into 2 groups according to the posterior angle, and there was a difference between the groups in the simotic index. The difference between groups may represent a genetic difference between the Jomon and Yayoi people and not only provide a new classification for the orbit of the population but also be useful in orbital reconstruction.Ovid Technologies (Wolters Kluwer Health), Jul. 2020, Journal of Craniofacial Surgery, Publish Ahead of Print(7) (7), 1875 - 1878, English, International magazineScientific journal
- Infantile hemangioma (IH) is a benign vascular tumor that gradually involutes over several years. Rapidly involuting congenital hemangioma (RICH) is the relatively rare congenital vascular tumor that is fully grown at birth and does not undergo postnatal growth and involutes during the first year. However, after involution of both IH and RICH, some have severe sequelae, such as redundant skin or conspicuous scarring, requiring additional treatment. We present the case of a 6-year-old girl with a concave deformity due to subcutaneous atrophy, skin darkening, and altered skin texture of her left zygomatic region following involution of a hemangioma. We successfully treated this patient by transferring a dermal fat graft. This technique can be beneficial for atrophic sequelae after regression of a hemangioma and is easy to perform and cosmetically effective.Lead, Wiley, Jul. 2020, Pediatric Dermatology, 37(4) (4), 776 - 779, English, International magazine[Refereed]Scientific journal
- Factors Preventing Prolonged Closed-Suction Drain Placement after Immediate Breast Reconstruction with Tissue Expanders.BACKGROUND: Prolonged drain placement occasionally causes complications such as infection in patients who have undergone implant-based breast reconstruction; therefore, the drainage period must be shortened to avoid complications. PURPOSE: To identify the factors that prevent prolonged drain placement in patients who have undergone immediate breast reconstruction with tissue expanders. METHODS: This was a retrospective medical chart review of all patients who underwent immediate breast reconstruction with tissue expanders at a single center from April 2013 to March 2016. Closed-suction drains were placed in and on the implant pocket. An extra drain was positioned in the axilla in patients undergoing axillary lymph node dissection. The drains were removed at a drainage volume of ≤50 ml per 24 hours. Prolonged drain placement was defined as a period greater than the 75th percentile among all patients. Nine potential risk factors associated with prolonged drain placement were analyzed with multivariate logistic regression analysis. RESULTS: In total, 89 tissue expanders in 89 patients were placed in this study. Prolonged drain placement, determined as ≥9 days (range, 5-14 days), was significantly associated with body mass index ≥25 kg/m2, tissue expander size ≥500 ml, and intraoperative bleeding ≥100 ml, in the multivariate analysis. Axillary lymph node dissection with extra-axillary drainage did not prolong the drainage period. CONCLUSIONS: Our findings suggested that placing an extra-axillary closed-suction drain following axillary dissection, and reducing intraoperative bleeding and surgical trauma, could prevent prolonged drain placement in immediate breast reconstruction with tissue expanders.Feb. 2020, The Kobe journal of medical sciences, 65(4) (4), E132-E137, English, Domestic magazineScientific journal
- OBJECTIVE: Free flap reconstruction in elderly patients is one of the most challenging surgeries in the treatment of head and neck cancers. The aim of this study was to examine the oncological and functional outcomes of free flap reconstruction for elderly patients with head and neck cancer. METHODS: We retrospectively reviewed elderly patients who underwent free flap reconstruction for the treatment of head and neck cancers. All patients were 80 years or older. Clinicopathologic features, surgical procedures, oncological and functional outcomes were obtained from medical records. RESULTS: Free flap reconstructions were performed in 13 patients (3 female, 10 male). The mean age was 82.6 ± 3.4 years (range: 80-91). The mean follow-up period was 23.3 months (range 4-41 months). The mean disease-free survival was 49 ± 6 months (range 4-60 months). All patients had been alive more than one year after surgery. Reconstruction was performed using free jejunum in 10 patients and radial forearm flap in 3 patients. Graft necrosis occurred in 2 patients. Other two patients experienced major postoperative medical complications. CONCLUSION: Free flap reconstruction in well-selected older adults is safe and effective. Advanced age should not preclude consideration of free flap reconstruction in those patients.Feb. 2020, Auris, nasus, larynx, 47(1) (1), 123 - 127, English, International magazine[Refereed]
- CLOVES syndrome is characterized by congenital lipomatous overgrowth, vascular malformation, epidermal nevi, and scoliosis/spinal malformation. It is caused by somatic mosaicism of gain-of-function variants of PIK3CA. Here, we describe a novel case of a 5-year-old Japanese girl with CLOVES and concurrent pancreatic steatosis. She had a recurrent somatic mutation in PIK3CA (NM_006218.3: c.1357G>A, p.Glu453Lys), elevated HbA1c levels, and pancreatic steatosis. This case indicates that pancreatic screening is critical for PIK3CA-related disorders.2019, Human genome variation, 6(6) (6), 31 - 31, English, International magazine[Refereed]Scientific journal
- Teratomas and lymphatic malformations are included in the differential diagnosis of congenital neck masses. They can exhibit similar clinical findings. The authors present a case of mature teratoma that had been managed as a lymphatic malformation for years. Clinicians should be careful not to dismiss clues for the correct diagnosis.Informa UK Limited, Jan. 2019, Case Reports in Plastic Surgery and Hand Surgery, 6(1) (1), 63 - 68, English, International magazineScientific journal
- A reverse vascular pedicle digital island flap is a useful treatment option for reconstruction in fingertip amputation. We describe a surgical procedure to preserve the dorsal branch of the digital nerve in the middle phalanx during elevation of this flap with favourable outcomes.Informa UK Limited, Jan. 2019, Case Reports in Plastic Surgery and Hand Surgery, 6(1) (1), 74 - 78, English, International magazineScientific journal
- INTRODUCTION: Diffuse plexiform neurofibroma (DPN) in patients with neurofibromatosis type 1 (NF1) causes motility dysfunction in severe cases. Transcatheter arterial embolisation (TAE) is an effective haemorrhage control method in vascular tumour surgery. PRESENTATION OF CASE: We performed debulking surgery for DPN in the buttock and posterior thigh of two NF1 patients. Preoperative TAE with gelatine particles to tumour feeder vessels was conducted in both cases. Operative bleeding volumes were 500 and 4970 mL, respectively. In the latter case, the resection area extended to the upper poles of the buttocks, and the tumour invaded deeply into the surrounding tissues. Massive haemorrhage occurred, and internal iliac arterial balloon was inflated temporarily to further suppress the bleeding. Delayed wound healing due to TAE occurred; debridement and wound closure were required. Motor function improvement was confirmed in both patients. DISCUSSION: Bleeding volumes varied because of highly developed collateral pathways and tumour invasiveness. As the upper pole of the buttock was perfused by the superior gluteal artery and its numerous collateral vessels, complete haemostasis was difficult despite adequate TAE. Because delineating the tumour border from the normal tissue was impossible due to the high tumour invasiveness, cutting into the hypervascular tumour was inevitable. As gelatine particles were absorbed but remained within the vessels, prolonged wound ischaemia and delayed healing occurred. CONCLUSION: Although TAE with gelatine particles and balloon occlusion were reliable haemorrhage control methods in debulking surgery for lower limb DPN, optimal haemorrhage control technique, compatible with haemostasis and wound healing, was desired.Jan. 2019, Int J Surg Case Rep, 55, 132 - 135, English, International magazine[Refereed]Scientific journal
- Dec. 2018, 日本形成外科学会会誌, 38(12号) (12号), 652 - 658, Japanese退縮後に摘出術を行った耳下腺乳児血管腫の治療経験[Refereed]Scientific journal
- Kokuseido Publishing Co. Ltd, Apr. 2018, Japanese Journal of Plastic Surgery, 61(4) (4), 450 - 456, JapaneseA comparative study of ethanolamine oleate and polidocanol for sclerotherapy in venous malformationsScientific journal
- (一社)日本形成外科学会, Apr. 2018, 日本形成外科学会会誌, 38(4) (4), 218 - 218, Japanese重度カリフラワー耳に対する肋軟骨移植術の治療経験
- Apr. 2018, 形成外科, 61(4号) (4号), 450 - 456, Japanese静脈奇形に対する硬化療法におけるオレイン酸エタノールアミンとポリドカノールの比較検討[Refereed]Scientific journal
- Kokuseido Publishing Co. Ltd, Jan. 2018, Japanese Journal of Plastic Surgery, 61(1) (1), 53 - 58, JapaneseUsefulness of iliac cancellous bone grafts in orbital fracture surgeryScientific journal
- (一社)日本マイクロサージャリー学会, Dec. 2017, 日本マイクロサージャリー学会学術集会プログラム・抄録集, 44回, 84 - 84, Japanese皮弁・切断指モニタリングのアップデート 当科における移植皮弁モニタリング法の選択 感度と簡便さを満たす最適な組み合わせとは
- (一社)日本マイクロサージャリー学会, Dec. 2017, 日本マイクロサージャリー学会学術集会プログラム・抄録集, 44回, 146 - 146, Japanese2回の遊離皮弁を含む複数回の手術加療を経て治癒した基礎疾患を有する脛骨開放骨折後感染症例の治療経験
- (一社)日本マイクロサージャリー学会, Dec. 2017, 日本マイクロサージャリー学会学術集会プログラム・抄録集, 44回, 147 - 147, Japanese当科での四肢における遊離皮弁移植の検討
- (一社)日本形成外科学会, Nov. 2017, 日本形成外科学会会誌, 37(11) (11), 667 - 668, Japanese節外性NK/T細胞リンパ腫鼻型の内科的治療後の外鼻変形に対して再建を要した1例
- (NPO)日本レーザー医学会, Oct. 2017, 日本レーザー医学会誌, 38(3) (3), 315 - 315, Japanese
- Kokuseido Publishing Co. Ltd, Jun. 2017, Japanese Journal of Plastic Surgery, 60(6) (6), 649 - 660, JapaneseSurgical treatment of arteriovenous malformationsScientific journal
- 克誠堂出版, Jun. 2017, 形成外科, 60(6号) (6号), 649 - 660, Japanese【頭頸部動静脈奇形の最新治療】 動静脈奇形に対する手術療法 nidusを見極めるわれわれの試み[Refereed]Scientific journal
- (一社)日本皮膚悪性腫瘍学会, May 2017, 日本皮膚悪性腫瘍学会学術大会プログラム・抄録集, 33回, 184 - 184, JapanesePerineural invasion(PNI)を示したCutaneous squamous cell carcinoma(SCC)の4例
- (一社)日本形成外科学会, Apr. 2017, 日本形成外科学会会誌, 37(4) (4), 207 - 208, Japaneseperipherally inserted central catheter(PICC)挿入時にガイドワイヤーの一部が遺残し、腱内に迷入していた1症例
- The Japanese Skin Cancer Society, Mar. 2017, Skin Cancer, 31(3号) (3号), 233 - 237, Japanese
The present case was of a 67-year-old male patient, who detected a black spot under his left hallux nail plate approximately one year prior to his initial medical examination. Subsequently, the lesion expanded, causing destruction of the nail ; this led the patient to undergo an examination at the department of dermatology at our hospital. Clinical analysis revealed primary malignant melanoma in the left hallux. Based on positron emission tomography-computed tomography results, the patient was suspected to have popliteal and inguinal lymph node metastasis ; he was therefore referred to our department. We performed a primary tumor resection, a sentinel lymph node biopsy, and a popliteal lymph node dissection. The primary tumor had a thickness of 11 mm and had infiltrated the periosteum. The inguinal lymph node biopsy was 1/3 positive (denoting metastasis to superficial inguinal lymph node) and the popliteal lymph node dissection was 1/2 positive (denoting metastasis to deep popliteal lymph node). At a later date, we performed an inguinal lymph node dissection and lymph node metastasis was no longer observed. Invasion of the primary tumor up to the hallux periosteum suggested that the tumor may have metastasized to the deep popliteal lymph node from the periosteum via deep lymphatic vessels. In conclusion, in cases where a primary tumor extends to deep tissues, it is important to consider the possibility of flow to deep lymphatic vessels.[Skin Cancer (Japan) 2016 ; 31 : 233-237]
[Refereed]Scientific journal - A Novel Method of Noninvasive Monitoring of Free Flaps With Near-Infrared Spectroscopy.Objective: Thrombosis of a site of anastomosis in microsurgical free tissue transfer can result in tissue necrosis. To salvage potentially failing free flap, various methods of monitoring the viability of tissue have been described. We report a novel method of monitoring free flaps using near-infrared spectroscopy. Methods: After microsurgical operation, we monitored the regional oxygen saturation of the flap with using the In-Vivo Optical Spectroscopy. A total of 57 patients participated in this study. Results: Of 57 cases, arterial insufficiency was detected in 1 case and venous insufficiency was detected in 3 cases. Regional oxygen saturation decreased before the flap color changed to a pale or congestive color. We could salvage these 4 patients by re-exploration. Conclusions: The postoperative monitoring with the In-Vivo Optical Spectroscopy is noninvasive, continuous, reliable, and reproducible. This technique could be one of the best methods for monitoring microsurgical free tissue transfers.2017, Eplasty, 17, e37, English, International magazine[Refereed]Scientific journal
- Low-Grade Myxofibrosarcoma of the Rectus Abdominus Muscle Infiltrating into Abdominal Cavity: A Case Report.Objective: Myxofibrosarcoma (MFS) is a relatively rare tumor that is histologically characterized by myxoid stroma and spindle cell proliferation. This tumor most commonly arises as a slow growing, enlarging painless mass in the extremities of elderly patients. Methods: We report a case of a primary, low-grade MFS in the rectus abdominis muscle infiltrating the abdominal cavity of a 75-year-old man. Results: The patient underwent a wide excision of the right abdominal wall mass with a 3-cm surgical margin from the scar due to a biopsy. The tumor infiltrated the urinary bladder, peritoneum, and external iliac vessels. Twenty-six months after the initial operation, he had recurrences in his abdominal wall, urinary bladder, and right iliac vessels. Conclusions: To our knowledge, primary MFS of the muscle in the abdomen has not been documented previously. Although this case was histopathologically classified as a low-grade tumor, it infiltrated the abdominal cavity. The tumor is suspected to have penetrated the abdominal cavity below the linea arcuata, which lacks the posterior sheath of the rectus abdominis muscle; from there, it could easily spread without being blocked by any biological barriers.2017, Eplasty, 17, e6, English, International magazine[Refereed]Scientific journal
- (一社)日本マイクロサージャリー学会, Nov. 2016, 日本マイクロサージャリー学会学術集会プログラム・抄録集, 43回, 105 - 105, Japanese皮弁移植術を極める 当科における遊離前腕皮弁移植を用いた再建戦略
- (一社)日本マイクロサージャリー学会, Nov. 2016, 日本マイクロサージャリー学会学術集会プログラム・抄録集, 43回, 175 - 175, Japanese術後血流不全により緊急再開創術を要した遊離空腸移植症例の検討
- (一社)日本マイクロサージャリー学会, Nov. 2016, 日本マイクロサージャリー学会学術集会プログラム・抄録集, 43回, 284 - 284, Japanese骨盤内臓全摘後に遊離広背筋皮弁移植による会陰部再建術を行った症例の検討
- (一社)日本頭蓋顎顔面外科学会, Oct. 2016, 日本頭蓋顎顔面外科学会誌, 32(3) (3), 213 - 213, Japaneseレックリングハウゼン病の下眼瞼外反に対し耳介軟骨移植とCaraji anchor suture systemで吊上げを行った1例
- (一社)日本皮膚悪性腫瘍学会, May 2016, 日本皮膚悪性腫瘍学会学術大会プログラム・抄録集, 32回, 142 - 142, Japanese皮膚切除を伴う骨盤内臓全摘後に遊離広背筋皮弁移植による再建術を行った症例の検討
- (NPO)日本レーザー医学会, Apr. 2016, 日本レーザー医学会誌, 37(1) (1), 58 - 64, Japanese
- BACKGROUND: The purpose of this study was to analyze outcomes for the treatment of locally advanced temporal bone cancer by means of concomitant chemoradiotherapy (CCRT) with a combination of cisplatin (CDDP), 5-fluorouracil (5-FU), and docetaxel (TPF). METHODS: Between 2006 and 2011, 34 patients with squamous cell carcinoma of the temporal bone were treated at Kobe University Hospital. Medical records were retrospectively reviewed to obtain information concerning patient characteristics, extent of disease, treatment, adverse events, and oncologic results. RESULTS: Ten patients were treated with CCRT using TPF regimen. The 5-year overall survival rate and disease-free survival rate were both 60%. Of special interest is that even for patients with unresectable T4 disease, the 5-year overall survival rate was 56%. CONCLUSION: The results of our study indicate that CCRT with TPF for locally advanced temporal bone cancer is an effective and promising regimen. © 2015 Wiley Periodicals, Inc. Head Neck 38: E949-E953, 2016.Apr. 2016, Head & neck, 38 Suppl 1, E949-53 - 53, English, International magazine[Refereed]Scientific journal
- (一社)日本形成外科学会, Mar. 2016, 日本形成外科学会会誌, 36(3) (3), 144 - 144, Japanese創内持続陰圧洗浄療法を用いた下腿コンパートメント症候群後皮膚潰瘍の治療
- 2016, Oncoplastic Breast Surgery, 1(2) (2), 1 - 6, Japanese[Refereed]Scientific journal
- (一社)日本マイクロサージャリー学会, Dec. 2015, 日本マイクロサージャリー学会会誌, 28(4) (4), 216 - 220, Japanese
- (一社)日本形成外科学会, May 2015, 日本形成外科学会会誌, 35(5) (5), 310 - 310, Japanese自家組織を用いた乳房二次再建における紙粘土による簡便なシミュレーション法
- May 2015, CYTOTECHNOLOGY, 67(3) (3), 507 - 514, English[Refereed]Scientific journal
- May 2015, JOURNAL OF RECONSTRUCTIVE MICROSURGERY, 31(4) (4), 305 - 312, English[Refereed]Scientific journal
- Negative pressure wound therapy (NPWT) has been introduced as a useful technique for wound treatment. However, some complications have been reported, such as infection, bleeding and pain, which make it impossible for patients to continue further treatment. Air leak is another problem, especially in hairy regions, such as the head and genital area. We have introduced a silicone gel adhesive dressing for NWPT, instead of using the film included in the original kit. The use of the silicone gel adhesive dressing greatly reduces pain, which was occurs when detaching the film. In addition, it plays a role in reducing air leak in hairy regions. Although there remains the problem of its high cost, silicone gel adhesive dressing for NPWT is quite useful.Japan Society for Surgical Wound Care, 2015, Jpn. J. Surg. Wound Care, 6(4) (4), 125 - 131, Japanese
- Simple and easy surgical technique for infantile hemangiomas: intralesional excision and primary closureOBJECTIVE: Infantile hemangioma (IH) is a benign vascular tumor that gradually shrinks over several years. Involuting or involuted IHs usually retain their shape, however, and result in redundant skin or conspicuous scarring due to ulceration in the proliferating phase. We present a case series of 12 patients who underwent intralesional excision and primary closure for treatment of involuting or involuted IH. METHODS: Twelve patients (5 boys, 7 girls) underwent our treatment method for involuting or involuted IH. A blinded assessor evaluated clinical result of each patient. RESULTS: Surgical results were excellent in 4 patients, good in 6, and fair in 2. A small dog ear was prominent in 1 patient; nevertheless, all parents were satisfied with the results. CONCLUSIONS: Intralesional excision and primary closure for treatment of involuting or involuted IH is an easy and simple procedure that does not result in dog-ear formation or elongated residual scarring.Jan. 2015, Eplasty, 15(-) (-), e3, English, International magazine[Refereed]Scientific journal
- (一社)日本頭蓋顎顔面外科学会, Dec. 2014, 日本頭蓋顎顔面外科学会誌, 30(4号) (4号), 171 - 178, Japanese開頭術後頭部皮膚潰瘍の原因に関する検討とその対策 死腔形成と脳室-腹腔シャントが及ぼす影響について[Refereed]Scientific journal
- (一社)日本マイクロサージャリー学会, Sep. 2014, 日本マイクロサージャリー学会会誌, 27(3) (3), 79 - 88, Japanese
- Sep. 2013, MICROSURGERY, 33(6) (6), 454 - 459, English[Refereed]Scientific journal
- (一社)日本形成外科学会, Jun. 2013, 日本形成外科学会会誌, 33(6) (6), 461 - 461, Japaneseプロプラノロール投与後に外科的切除を行った乳児血管腫の1例
- (一社)日本形成外科学会, Jun. 2013, 日本形成外科学会会誌, 33(6) (6), 461 - 461, Japanese当科における静脈奇形に対する手術治療の経験
- (一社)日本頭頸部癌学会, May 2013, 頭頸部癌, 39(2号) (2号), 166 - 166, Japaneseがん切除後下顎骨再建における再建理論「CATコンセプト」 臨床症例における実践結果[Refereed]Research society
- (一社)日本形成外科学会, Sep. 2012, 日本形成外科学会会誌, 32(9) (9), 710 - 710, Japanese乳輪下膿瘍の3例
- (一社)日本形成外科学会, Sep. 2012, 日本形成外科学会会誌, 32(9) (9), 712 - 712, Japanese両側眼窩内腫瘍の1例
- (一社)日本皮膚悪性腫瘍学会, Jun. 2012, 日本皮膚悪性腫瘍学会学術大会プログラム・抄録集, 28回, 146 - 146, Japanese外科的治療を行った肺癌頭頸部転移症例の検討
- It is important to have sufficient thin, vascular lining for persistent good contour and nasal function in a nasal reconstruction. We have used the nasolabial flap as lining for two patients which required full-thickness reconstruction of the nose because of skin cancer. Case 1 : A 78-year-old man underwent resection for basal cell carcinoma of the nasal tip and ala. A nasolabial flap, median forehead flap and nasal septum cartilage were used for reconstructing the alar defect. Case 2 : A 76-year-old woman presented with contraction of the ala and columella after forearm flap transfer. The nasolabial flap was chosen to restore the nasal vault and columella. There were no complications and the postoperative result was acceptable. It is said that the nasolabial flap is thick and not highly vascular. Based on our experience, however, this flap can be safely used for nasal lining with satisfactory thinness.[Skin Cancer (Japan) 2012 ; 27 : 186-190]The Japanese Skin Cancer Society, 2012, Skin Cancer, 27(2) (2), 186 - 190, Japanese[Refereed]Scientific journal
- (一社)日本マイクロサージャリー学会, Jul. 2011, 日本マイクロサージャリー学会会誌, 24(2) (2), 168 - 168, Japanese新しい皮弁血流モニター法 INVOS:無侵襲混合血酸素飽和度監視装置を用いて(第2報)
- Sep. 2010, Skin Cancer, 25(2号) (2号), 195 - 199, JapaneseGluteal fold VY advancement flapに基づく再建を行った外陰癌の1症例[Refereed]Scientific journal
- 克誠堂出版(株), May 2008, 形成外科, 51(5) (5), 555 - 560, Japanese[Refereed]
- We reported two cases of basal cell carcinoma (BCC) that developed after radiation therapy. A 50-year-old woman, who had received an unknown amount of radiation therapy for the treatment of intracranial germinoma at the age of 22, presented with several tumors around the radiation ulcer. All tumors showed BCC. A 33-year-old woman, who had received an unknown amount of radiation therapy on the head for the treatment of leukemia at the age of 2, presented with a black nodule within the area of irradiation. The tumor showed BCC. We discuss the occurrence of BCC after radiation therapy. [Skin Cancer (Japan) 2007; 22: 256-262]The Japanese Skin Cancer Society, Mar. 2008, Skin Cancer, 22(3) (3), 256 - 262, Japanese
- We presented 6 cases who had undergone excision of skin metastases from lung cancer. The 6 patients, 4 male and 2 female, ranged in age from 57 to 76 years. The pathological findings were adenocarcinoma in four patients, and squamous cell carcinoma and small cell carcinoma in one patient. The median survival time from the diagnosis of lung cancer was 13.0 months and that from the diagnosis of skin metastasis was 6.2 months. We concluded that excision of skin metastases from lung cancer could not improve the vital prognosis. However, symptoms of the patients, including pain, exudate, and bleeding, were improved postoperatively, so we suggest that excision of skin metastases from lung cancer is an important procedure for improving the QOL of the patients. [Skin Cancer (Japan) 2008; 23: 47-52]The Japanese Skin Cancer Society, 2008, Skin Cancer, 23(1) (1), 47 - 52, Japanese[Refereed]
- The most frequent malignancy of the auricle is squamous cell carcinoma. Resection of auricular squamous cell carcinoma results in over one-third or one-fourth of auricular skin and cartilage defects. We experienced a case in which one half of the auricular skin and cartilage defects were due to auricular squamous cell carcinoma resection (T2N0M0 stage II) . We performed staged reconstruction of the auricle with the aim of auricular appearance and the functional purpose of wearing eyeglasses. We carried out auricular reduction in the affected side and cartilaginous graft transplantation from the unaffected side. Auricular wedge-shaped closure, chondrocutaneous advancement flap, temporoparietal fascial flap and split-thickness skin graft techniques were also employed.The Japanese Skin Cancer Society, 2008, Skin Cancer, 23(3) (3), 384 - 389, Japanese
One year after the auricular reconstruction, tumor recurrence and distal metastasis has not been observed. The reconstructed auricle is smaller than the unaffected auricle and has some deformity. However, the patient can wear eyeglasses. [Skin Cancer (Japan) 2008; 23: 384-389] - 日本シミュレーション外科学会, Jan. 2008, 日本シミュレーション外科学会会誌, 15(4) (4), 91 - 94, Japanese
- (一社)日本褥瘡学会, Aug. 2007, 日本褥瘡学会誌, 9(3) (3), 409 - 409, Japanese
- (一社)日本形成外科学会, Apr. 2007, 日本形成外科学会会誌, 27(4) (4), 346 - 346, Japanese血管奇形硬化療法における術中透視下病変造影の重要性 静脈奇形症例の検討
- 日本シミュレーション外科学会, Nov. 2006, 日本シミュレーション外科学会会誌, 14(1-2) (1-2), 42 - 42, Japanese
- (一社)日本頭蓋顎顔面外科学会, Sep. 2005, 日本頭蓋顎顔面外科学会誌, 21巻, 3号, pp.203-212(3) (3), 203 - 212, Japanese外鼻基底細胞癌100症例の必要切除深度に応じた部位別再建術式の選択[Refereed]Scientific journal
- Positive narrowing pharyngoplasty with forearm flap for functional restoration after extensive soft palate resectionThe restoration of velopharyngeal function after extensive soft palate resection to treat malignant oropharyngeal tumors is a major challenge to reconstructive surgeons. The authors had previously reconstructed soft palatal defects routinely with the folded forearm flap. A patient who had more than half of the soft palate excised experienced postoperative velopharyngeal dysfunction. To restore efficient velopharyngeal function, pharyngoplasty was additively applied where the folded ridge of the forearm flap was sutured to the posterior pharyngeal wall in an inverse manner of the pharyngeal flap technique. The essence of the procedure was positive narrowing of the nasopharyngeal space. Five patients who underwent this pharyngoplasty and another five who did not were evaluated for postoperative functions of speech intelligibility and of nasal regurgitation during oral feeding. The velopharyngeal movements of all patients were examined under a nasopharyngeal endoscope. The evaluations demonstrated that this surgical procedure afforded satisfactory results. This positive narrowing pharyngoplasty technique is simple, easy, and minimally invasive to the remaining healthy tissue, and it is the method of choice for the reconstruction of the soft palate after malignant tumor resection.2005, Plastic And Reconstructive Surgery, Vol. 115, No. 2, pp. 388-393(2) (2), 388 - 93, English, International magazine[Refereed]Scientific journal
- Jan. 2005, 日本口腔科学会雑誌, 54巻, 1号, pp. 127-127, JapanesePeriostesl blood supplyとdirect blood supplyによる骨生存形態を同時に観察し得た遊離腓骨皮弁再建の1例International conference proceedings
- Oct. 2004, Skin Cancer, 19巻, 2号, pp. 233-237, Japanese外陰部悪性黒色腫の治療経験[Refereed]Scientific journal
- Aug. 2004, 日本褥瘡学会誌, 6巻, 3号, pp. 417-417, Japanese褥瘡患者の便失禁に対する多孔性ポリウレタン素材肛門用装具(コンビーンアナルプラグ)の使用経験International conference proceedings
- Aug. 2004, 日本褥瘡学会誌, 6巻, 3号, pp. 430-430, Japanese放射線治療により創傷治癒が遅延した臀部褥瘡の一例International conference proceedings
- Aug. 2004, 日本褥瘡学会誌, 6巻, 3号, pp. 434-434, Japanese圧分布測定システム(FSA,VERG社製)を用いた座位における車椅子用体圧分散クッションの客観的評価International conference proceedings
- Jul. 2004, 日本口腔科学会雑誌, 53巻, 3号, pp. 143-143, Japanese同一の大胸筋皮弁にて2回の再建を施行した頬部未分化癌の1例 内側胸筋神経温存の有用性International conference proceedings
- (一社)日本マイクロサージャリー学会, Jun. 2004, 日本マイクロサージャリー学会会誌, 17(2) (2), 187 - 187, Japanese遊離皮弁移植により下腿切断を回避し得た症例
- Mar. 2004, 日本形成外科学会会誌, 24巻, 3号, pp. 214-214, Japaneseペーシングワイヤー残存による胸骨骨髄炎の1例International conference proceedings
- Mar. 2004, Journal Of Oral Science, Vol. 46, No. 1, pp. 65-70(1) (1), 65 - 70, English[Refereed]Scientific journal
- Do multiple venous anastomoses reduce risk of thrombosis in free-flap transfer? Efficacy of dual anastomoses of separate venous systemsWhether or not multiple venous anastomoses reduce the risk of free-flap failure is a subject of controversy. We report here, for the first time, on the importance of selecting 2 separate venous systems of the flap for dual anastomoses. The efficacy of multiple anastomoses was verified through a retrospective review of 310 cases of the free radial forearm flap transfer. Dual anastomoses of separate venous systems (the superficial and the deep) showed a lower incidence of venous insufficiency than single anastomosis did (0.7% versus 7.5%; P < 0.05). On the other hand, dual anastomoses of a sole venous system showed no significant difference in the incidence of venous insufficiency compared with single anastomosis (11.5% versus 7.5%; P = 0.48). Our results suggest that dual venous anastomoses of separate venous systems is conducive to reduced risk of flap failure and affords protection against venous catastrophe through a self-compensating mechanism that obviates thrombosis of either anastomosis.Jan. 2004, Annals Of Plastic Surgery, Vol. 52, No. 1, pp. 61-63(1) (1), 61 - 3, English, International magazine[Refereed]Scientific journal
- Dec. 2003, The British Journal Of Oral & Maxillofacial Surgery, Vol. 41, No. 6, pp. 380-382, English[Refereed]Scientific journal
- Dec. 2003, 日本ストーマリハビリテーション学会誌, 19巻, 3号, pp. 105-105, Japanese合併症 ストーマ周囲肉芽腫に対し硬化療法が有効であった一事例International conference proceedings
- Nov. 2003, 日本口腔科学会雑誌, 52巻, 6号, pp. 382-382, Japanese顎口腔再建での筋皮弁移植における支配神経温存,再形成の意義International conference proceedings
- Aug. 2003, 日本褥瘡学会誌, 5巻, 2号, pp. 377-377, Japanese精神疾患患者の褥瘡について(その2)International conference proceedings
- Aug. 2003, 日本褥瘡学会誌, 5巻, 2号, pp. 360-360, Japanese圧分布測定システム(FSA,VERG社製)を用いた体圧分散寝具の客観的評価International conference proceedings
- Aug. 2003, 日本褥瘡学会誌, 5巻, 2号, pp. 376-376, Japaneseベッドサイドのテレビの位置移動が褥瘡治癒に影響した1例の検討International conference proceedings
- Aug. 2003, 日本褥瘡学会誌, 5巻, 2号, pp. 310-310, Japaneseカデックス軟膏による皮膚への障害についての検討International conference proceedings
- Aug. 2003, 日本褥瘡学会誌, 5巻, 2号, pp. 314-314, JapaneseSLEと化膿性脊椎炎を合併した仙骨部褥瘡患者に対し多職種合同カンファレンスを行い褥瘡縮小に至った1例Scientific journal
- Jun. 2003, 日本熱傷学会機関誌, 29巻, 2号, pp. 117-117, Japanese熱傷後の脱色素斑に対する治療 Thin-minigraftingを用いてInternational conference proceedings
- Apr. 2003, 日本頭蓋顎顔面外科学会誌, 19巻, 1号, pp. 45-45, Japanese診断に難渋した顔面Low-grade fibromyxoid sarcomaの1例International conference proceedings
- Short-term postoperative flow changes after free radial forearm flap transfer: possible cause of vascular occlusion.The risk for free flap thrombosis is greatly influenced by blood flow. Postoperative hemodynamic changes in vascular pedicles of the microvascular skin flap have not been reported, however. This study focuses on the intraoperative and postoperative changes in the flow volume in the vascular pedicles of the free forearm flap examined by color Doppler ultrasonography. The arterial flow volume increased continuously until day 7, compared with which, the volume after flap elevation was 36%. On day 1, it reached only 52%. In the venous pedicle, the flow volume through the cutaneous vein was only 37% compared with that through the radial vena comitans after flap elevation, whereas the volume through both veins was equal on day 7. Drastic changes in the flow explain the possible vascular occlusion during the early postoperative period in the free forearm flap transfer.Feb. 2003, Annals of plastic surgery, 50(2) (2), 160 - 4, English, International magazineScientific journal
- 2003, Plastic and Reconstructive Surgery, 112(5) (5), 1228 - 1237, EnglishScientific journal
- (一社)日本褥瘡学会, 2003, 日本褥瘡学会誌, 5巻, pp. 33-36(1-1) (1-1), 33 - 36, JapaneseScientific journal
- 2003, Microsurgery, Vol. 23, No. 2, pp. 96-102, 96 - 102, EnglishIndications for vascularized free rectus abdominis musculocutaneous flap in oromandibular region in terms of efficiency of anterior rectus sheath[Refereed]Scientific journal
- (NPO)日本口腔科学会, Nov. 2001, 日本口腔科学会雑誌, 50(6) (6), 526 - 526, Japanese
- May 2001, Journal of Reconstructive Microsurgery, 17(4) (4), 225 - 228Scientific journal
- 2001, Journal of Cranio-Maxillofacial Surgery, 29(6) (6), 344 - 350Scientific journal
- (株)医学書院, Jul. 2024, 耳鼻咽喉科・頭頸部外科, 96(8) (8), 655 - 658, Japanese
- 医歯薬出版(株), May 2024, 医学のあゆみ, 289(7) (7), 491 - 495, Japanese
- (一社)日本皮膚悪性腫瘍学会, Feb. 2024, Skin Cancer, 38(3) (3), 159 - 165, Japanese
- 克誠堂出版(株), Feb. 2024, 形成外科, 67(2) (2), 137 - 142, Japanese
- 2024, 日本形成外科手術手技学会プログラム・抄録集, 29th脈管奇形に対する切除ならびに再建手術の工夫
- 2024, 日本形成外科学会会誌, 44(8) (8)顔面神経麻痺に対する鼻翼基部への筋膜移植の有効性
- 2024, 日本血管腫血管奇形学会学術集会プログラム・抄録集, 20th (CD-ROM)脈管奇形に対してシロリムスをどう使う?~当科での使用経験から得た知見~
- 2024, 日本形成外科学会総会・学術集会プログラム・抄録集, 67th特発性陰核肥大に対する陰核形成術をおこなった一例
- 2024, 日本形成外科学会総会・学術集会プログラム・抄録集, 67th顔面神経麻痺に対する鼻翼基部への筋膜移植の有効性
- 2024, 日本形成外科学会総会・学術集会プログラム・抄録集, 67th炭素イオン線照射後の鼻根部副鼻腔皮膚瘻に対する外科的再建の経験
- 2024, 日本形成外科学会総会・学術集会プログラム・抄録集, 67th動静脈奇形治療の未来を見据えて
- 克誠堂出版(株), Jan. 2024, 形成外科, 67(1) (1), 43 - 47, Japanese
- 克誠堂出版(株), Nov. 2023, 形成外科, 66(11) (11), 1283 - 1287, Japanese
- (一社)日本創傷治癒学会, Nov. 2023, 日本創傷治癒学会プログラム・抄録集, 53回, 77 - 77, Japanese重症下肢虚血患者の創傷治療の現状と展望 レオカーナを用いた血液浄化療法による創傷治療
- (一社)日本頭蓋顎顔面外科学会, Nov. 2023, 日本頭蓋顎顔面外科学会学術集会プログラム・抄録集, 41回, 146 - 146, Japanese人工骨を用いた頬骨上顎骨複合体欠損症例に対する二次再建の経験
- (一社)日本脈管学会, Oct. 2023, 脈管学, 63(Suppl.) (Suppl.), S125 - S125, Japanese血管腫・血管奇形・リンパ管奇形診療ガイドライン改訂とこれからの診療 リンパ管奇形におけるガイドライン改訂とこれからの診療への活用
- (一社)日本形成外科学会, Aug. 2023, 日本形成外科学会会誌, 43(8) (8), 484 - 484, Japaneseマイクロサージャリー 脈管奇形摘出における血管剥離
- (一社)日本形成外科学会, Aug. 2023, 日本形成外科学会会誌, 43(8) (8), 495 - 496, Japanese私たちの流儀 開心術後縦隔炎に対するデブリードマン
- (一社)日本皮膚悪性腫瘍学会, Jun. 2023, 日本皮膚悪性腫瘍学会学術大会プログラム・抄録集, 39回, 111 - 111, Japanese【最良の再建を目指して】最良の外鼻再建を目指す必要条件とは
- (一社)日本形成外科学会, Apr. 2023, 日本形成外科学会会誌, 43(4) (4), 233 - 233, Japanese上眼瞼脂腺癌の二期的再建後に生じた瞼球癒着
- 2023, 頭頸部癌, 49(2) (2)進行涙腺癌に対する眼窩内容及び眼窩上外側骨一塊切除後前頭蓋底再建手術~機能と整容に対する配慮~
- 2023, 日本形成外科学会総会・学術集会プログラム・抄録集, 66thマイクロサージャンとして鑷子を研ぐ
- 2023, 日本形成外科学会総会・学術集会プログラム・抄録集, 66th耳下腺悪性腫瘍切除後の即時顔面神経再建症例における術後経過の検討
- 2023, 日本形成外科学会総会・学術集会プログラム・抄録集, 66th上顎骨内動静脈奇形切除術における複合的治療と手術デバイスの工夫
- 2023, 日本形成外科学会基礎学術集会プログラム・抄録集, 32nd抗攣縮薬の血管拡張効果と血管平滑筋細胞および内皮細胞に対する細胞毒性
- (一社)日本頭蓋顎顔面外科学会, Nov. 2022, 日本頭蓋顎顔面外科学会学術集会プログラム・抄録集, 40回, 80 - 80, Japanese顔面皮膚悪性腫瘍手術に対するAesthetic mind 外鼻における皮膚悪性腫瘍切除と再建において形成外科医に求められること
- (一社)日本頭蓋顎顔面外科学会, Nov. 2022, 日本頭蓋顎顔面外科学会学術集会プログラム・抄録集, 40回, 121 - 121, Japanese3Dモデルを用いて移植肋軟骨片の形態を決定した陳旧性眼窩骨折の3例
- (一社)日本頭蓋顎顔面外科学会, Nov. 2022, 日本頭蓋顎顔面外科学会学術集会プログラム・抄録集, 40回, 124 - 124, Japanese頭蓋再建における前腕皮弁による頭皮再建
- (公社)日本医学放射線学会, Sep. 2022, 日本医学放射線学会秋季臨床大会抄録集, 59回, S308 - S308, Japanese脈管奇形・リンパ管の画像診断と治療戦略(診断) 画像診断から判断する脈管奇形の治療戦略 形成外科医の立場から
- Lead, 克誠堂出版(株), Jun. 2022, 形成外科, 65増刊(増刊) (増刊), S246 - S257, Japanese
- (株)全日本病院出版会, Feb. 2022, PEPARS, (182) (182), 35 - 41, Japanese【遊離皮弁をきれいに仕上げる-私の工夫-】遊離皮弁を用いた頭蓋再建
- 2022, 日本創傷外科学会総会・学術集会プログラム・抄録集, 14th顔面,頸部深達性熱傷後に複数回に及ぶ手術で顔面再建を行なった1例
- (株)全日本病院出版会, Jan. 2022, PEPARS, (181) (181), 74 - 81, Japanese【まずはここから!四肢のしこり診療ガイド】筋増殖疾患、筋原性腫瘍
- (株)医学書院, Dec. 2021, 耳鼻咽喉科・頭頸部外科, 93(13) (13), 1124 - 1127, Japanese
- (株)全日本病院出版会, Sep. 2021, Orthopaedics, 34(9) (9), 11 - 17, Japanese
- (株)日本医事新報社, Aug. 2021, 日本医事新報, (5076) (5076), 45 - 45, Japanese
- 2021, 日本形成外科学会基礎学術集会プログラム・抄録集, 30th各種血管抗攣縮薬における血管平滑筋細胞への細胞毒性の検討
- 2021, 日本病理学会会誌, 110(1) (1)Three cases of mature teratoma with pineal gland differentiation
- (一社)日本頭蓋顎顔面外科学会, Nov. 2020, 日本頭蓋顎顔面外科学会学術集会プログラム・抄録集, 38回, 83 - 83, Japanese「頭頸部の難渋する良性疾患I(NF-1、血管疾患)」 頭頸部の難治性血管性病変に対する治療戦略
- (一社)日本頭蓋顎顔面外科学会, Nov. 2020, 日本頭蓋顎顔面外科学会学術集会プログラム・抄録集, 38回, 114 - 114, Japanese眼球結膜の部分切除を施行した眼瞼基底細胞癌の1例
- (一社)日本頭蓋顎顔面外科学会, Oct. 2019, 日本頭蓋顎顔面外科学会学術集会プログラム・抄録集, 37回, 100 - 100, Japanese顔面・頭皮悪性腫瘍の再建 私の流儀:遊離皮弁を用いないでここまで治せる 顔面の再建材料選択に関する私の流儀
- (一社)日本頭蓋顎顔面外科学会, Oct. 2019, 日本頭蓋顎顔面外科学会学術集会プログラム・抄録集, 37回, 124 - 124, Japaneseテーラーメイドのリジッドキャリアを利用した眼窩骨折の再建法 熱可塑性プラスチックを用いた工夫
- 2019, PAPERS., 145, 27 - 35リンパ管奇形の診断と治療.
- 2019, 日本形成外科学会総会・学術集会プログラム・抄録集, 62nd右下腿前面に生じた類上皮肉腫の治療経験
- Oct. 2018, PEPARS, (142号) (142号), 33 - 41, Japanese【STEP UP!Local flap】 眼周囲で有用な局所皮弁 皮下茎皮弁による再建方法Introduction commerce magazine
- (一社)日本形成外科学会, Aug. 2018, 日本形成外科学会会誌, 38(8) (8), 457 - 457, Japanese左中指の腱鞘線維腫の一例
- Jul. 2018, 形成外科, 61(増刊) (増刊), S229 - S237, Japanese【形成外科 珠玉のオペ[2]応用編-次世代に継承したい秘伝のテクニック-】 四肢・体幹外科 血管腫 血液貯留型血管奇形に対する手術療法[Refereed]Introduction commerce magazine
- Jan. 2018, 形成外科, 61(1号) (1号), 53 - 58, Japanese【眼窩壁再建における材料の選択】 眼窩骨折に対する腸骨髄質移植[Refereed][Invited]Introduction commerce magazine
- Dec. 2017, 形成外科, 60(12号) (12号), 1359 - 1363, Japanese【レーザー治療の合併症から学ぶ】 乳児血管腫に対する早期レーザー治療により潰瘍を生じた1例[Refereed]Introduction scientific journal
- Sep. 2017, 日本医事新報, (4871号) (4871号), 7 - 8, Japanese似たもの画像、あいまい画像を一刀両断! 画像診断道場 実はこうだった(第74回) 急速に増大する耳下部の皮下腫瘤 診断・治療は?Introduction commerce magazine
- Sep. 2017, JOHNS, 33(9号) (9号), 1215 - 1217, Japanese【頭頸部悪性腫瘍の疑問に答える】 治療選択 基底細胞癌の治療を教えてくださいIntroduction commerce magazine
- 克誠堂出版, Aug. 2017, 形成外科, 60(8号) (8号), 859 - 873, Japanese【形成外科が扱う皮膚疾患の現在】 形成外科が扱う皮膚良性疾患のマクロ診断と手術治療Introduction scientific journal
- Jun. 2017, 日本形成外科学会会誌, 37(6号) (6号), 341, Japanese不全切断指の血行評価にICG蛍光造影法を用いた1例[Refereed]Meeting report
- 2017, NHKテキストきょうの健康, 3, 114 - 114, Japaneseなんでも健康相談.「血管腫」について教えてくださいIntroduction commerce magazine
- 全日本病院出版会, Dec. 2016, Pepars, (120) (120), 29 - 37, Japanese顔面の遊離植皮術の適応と実際 (特集 イチから見直す植皮術)
- Dec. 2016, Oncoplastic Breast Surgery, 1(2号) (2号), 82 - 87, Japanese非常勤形成外科医による乳房一次再建症例の検討[Refereed]
- (一社)日本形成外科学会, Jul. 2016, 日本形成外科学会会誌, 36(7号) (7号), 352 - 352, Japanese食道癌術後胃管気管支瘻に対して有茎広背筋弁を用いて閉鎖した1例[Refereed]Meeting report
- Apr. 2016, 日本レーザー歯学会誌, 27(1号) (1号), 21 - 26, JapaneseIntroduction scientific journal
- 全日本病院出版会, Mar. 2016, PEPARS, (111) (111), 1 - 9, Japanese毛細血管奇形(単純性血管腫)の標準的レーザー治療[Refereed]Introduction commerce magazine
- 日本皮膚悪性腫瘍学会, Mar. 2016, Skin Cancer, 30(3号) (3号), 157 - 162, Japanese[Refereed]Introduction scientific journal
- 2016, PAPERS, 120, 29 - 37, Japanese顔面の植皮[Refereed]Introduction commerce magazine
- (一社)日本マイクロサージャリー学会, Nov. 2015, 日本マイクロサージャリー学会学術集会プログラム・抄録集 42回, 42回, 206 - 206, Japanese無侵襲混合血酸素飽和度監視システム:INVOSを用いた遊離皮弁術後モニタリングMeeting report
- 全日本病院出版会, Apr. 2015, PEPARS, (100号) (100号), 23 - 33, Japanese【皮膚外科のための皮膚軟部腫瘍診断の基礎】 臨床ならびに病理診断 皮膚外科のための腫瘍病理の見方Introduction scientific journal
- (一社)日本マイクロサージャリー学会, Dec. 2014, 日本マイクロサージャリー学会学術集会プログラム・抄録集 41回, 41回, 161 - 161, Japanese複数回の化学放射線療法を施行された多重癌患者に対する遊離広背筋皮弁を用いた頭蓋再建の経験Others
- Dec. 2014, 日本マイクロサージャリー学会学術集会プログラム・抄録集 41回, 204, Japanese悪性腫瘍切除後に生じた胸腹壁欠損に対する再建術式の検討Others
- (一社)日本形成外科学会, Nov. 2014, 日本形成外科学会会誌, 34(11号) (11号), 851 - 851, Japanese再発胃癌切除後に生じた胸腹壁欠損に対する治療経験Others
- (一社)日本形成外科学会, Nov. 2014, 日本形成外科学会会誌, 34(11号) (11号), 860 - 860, Japanese骨および関節露出を伴う足背部潰瘍の地道な保存加療による治療経験Others
- (一社)日本マイクロサージャリー学会, Sep. 2014, 日本マイクロサージャリー学会会誌, 27(3号) (3号), 72 - 78, Japanese[Refereed]Introduction scientific journal
- Jul. 2014, 日本皮膚悪性腫瘍学会学術大会プログラム・抄録集 30回, 132, Japanese腫瘍切除後に生じた胸腹壁欠損に対する再建手術の検討Others
- May 2014, 日本形成外科学会会誌, 34(5号) (5号), 392, Japanese遊離皮弁移植のコツ 遊離皮弁移植の術前計画における画像検査の有用性Others
- 全日本病院出版会, Apr. 2014, PEPARS, (88号) (88号), 14 - 22, Japanese【コツがわかる!形成外科の基本手技-後期臨床研修医・外科系医師のために-】 ケロイドと肥厚性瘢痕の病態と治療法[Invited]Introduction scientific journal
- 克誠堂出版, Dec. 2013, 形成外科, 56(12号) (12号), 1271 - 1280, Japanese【皮弁移植に必要な血管の術前評価】 フェーズラグCTA(pl-CTA)による静脈術前評価[Refereed]Introduction commerce magazine
- Nov. 2013, 日本シミュレーション外科学会会誌, 21(2号) (2号), 96 - 97, Japanese血管奇形に対するエコーガイド下硬化療法の経験 有用性と問題点について[Refereed]Meeting report
- Nov. 2013, 薬局, 64(12号) (12号), 2979 - 2983, Japanese【小外傷・熱傷・褥瘡 創傷に対応する「ワザ」と「知恵」】 急性創傷のピットフォール!誤った対応をしないポイント すぐに家に帰らせてはいけない一見軽微な急性創傷を見逃さないポイント[Refereed][Invited]Introduction scientific journal
- (一社)日本マイクロサージャリー学会, Sep. 2013, 日本マイクロサージャリー学会学術集会プログラム・抄録集40周年記念, 40周年記念, 199 - 199, Japanese遊離皮弁による頭蓋再建症例の検討[Refereed]Meeting report
- (一社)日本マイクロサージャリー学会, Sep. 2013, 日本マイクロサージャリー学会学術集会プログラム・抄録集40周年記念, 40周年記念, 127 - 127, Japanese血管吻合術後の管理と移植組織サルベージ法の実際 多様な血管吻合術後皮弁モニタリング[Refereed]Meeting report
- (一社)日本マイクロサージャリー学会, Sep. 2013, 日本マイクロサージャリー学会学術集会プログラム・抄録集40周年記念, 40周年記念, 136 - 136, Japanese移植皮弁の選択 私のファーストチョイス 足部・下腿に用いる皮弁 Contourを重視した足部および下腿遠位部の再建法[Refereed][Invited]Meeting report
- Aug. 2013, 日本臨床, 71(増刊4 皮膚悪性腫瘍) (増刊4 皮膚悪性腫瘍), 633 - 638, Japanese【皮膚悪性腫瘍-基礎と臨床の最新研究動向-】 基底細胞癌 基底細胞癌の治療 外科的治療[Refereed][Invited]Introduction commerce magazine
- Jul. 2013, 静脈経腸栄養, 28(4) (4), 939 - 943, JapaneseIntroduction scientific journal
- 全日本病院出版会, Jul. 2013, PEPARS, (79号) (79号), 38 - 45, Japanese【褥瘡の治療 実践マニュアル】 褥瘡の保存的治療 被覆材と体圧分散方法Introduction commerce magazine
- Jul. 2013, 静脈経腸栄養, 28(4号) (4号), 939 - 943, Japanese[Refereed][Invited]Introduction scientific journal
- 克誠堂出版, Apr. 2013, 形成外科, 56(4) (4), 451 - 456, JapaneseA Case Report of Bilateral Orbital Tumor Diagnosed as Mikulicz's Disease by Biopsy
- (一社)日本マイクロサージャリー学会, Dec. 2012, 日本マイクロサージャリー学会学術集会プログラム・抄録集39回, 39回, 301 - 301, Japanese遊離皮弁を用いた頭頸部再建症例における周術期抗凝固療法の合併症について VTE予防の観点から[Refereed]Meeting report
- Dec. 2012, 日本マイクロサージャリー学会学術集会プログラム・抄録集39回, 230, Japanese微小脈管吻合における直針付き縫合糸の有用性[Refereed]Meeting report
- (一社)日本マイクロサージャリー学会, Dec. 2012, 日本マイクロサージャリー学会学術集会プログラム・抄録集39回, 39回, 207 - 207, Japanese後期高齢者に対するマイクロサージャリーは危険か?[Refereed]Meeting report
- Dec. 2012, 日本マイクロサージャリー学会学術集会プログラム・抄録集39回, 158, Japaneseリンパ浮腫の治療 簡易に良結果を得る方法 リンパ管静脈吻合手技を容易にするためのアイデアと工夫[Refereed]Meeting report
- Dec. 2012, 日本マイクロサージャリー学会学術集会プログラム・抄録集39回, 221, Japanese3D-CTA像の体表への投射を利用した血管マーキング[Refereed]Meeting report
- 20 Oct. 2012, 日形会誌 : 日本形成外科学会会誌 = Journal of Japan Society of Plastic and Reconstructive Surgery, 32(10) (10), 734 - 738, JapaneseIdiopathic Orbital Inflammation Diagnosed Inflammatory Myofibroblastic Tumor after Recurrence
- Oct. 2012, 日本レーザー医学会誌, 33(3号) (3号), 307, Japanese赤唇部の毛細血管奇形(単純性血管腫)に対するパルス色素レーザー照射効果の検討[Refereed]Meeting report
- 国立病院機構姫路医療センター, 2011, 独立行政法人国立病院機構姫路医療センター紀要, 12, 37 - 40, JapaneseComa blister 4症例の治療経験
- 克誠堂出版, Oct. 2009, Japanese journal of plastic surgery, 52(10) (10), 1173 - 1182, JapaneseSclerotherapy skills for vascular malformations and prevention of complications
- 25 Mar. 2009, 日本頭蓋顎顔面外科学会誌 = Journal of the Japan Society of Cranio-Maxillo-Facial Surgery, 25(1) (1), 60 - 67, JapaneseSimple Reconstruction of Subtotal Maxillectomy Defects Using Free Flaps
- 克誠堂出版, Mar. 2009, Japanese journal of plastic surgery, 52(3) (3), 325 - 331, JapaneseTwo cases of antegrade venous anastomosis employed on distally-based flap from dorsal foot
- 国立病院機構姫路医療センター, 2009, 独立行政法人国立病院機構姫路医療センター紀要, 11, 17 - 19, Japanese足趾Garlic-clove fibromaの2症例
- 25 May 2008, 静脈学, 19(3) (3), 161 - 168, JapaneseOur Strategy for the Treatment of Venous Malformations
- May 2008, WOUND REPAIR AND REGENERATION, 16(3) (3), 468 - 468, EnglishLipid analysis of normal dermis and hypertrophic scars (vol 15, pg 833, 2007)Others
- Nov. 2007, DERMATOLOGIC SURGERY, 33(11) (11), 1368 - 1373, EnglishOthers
- Nov. 2007, WOUND REPAIR AND REGENERATION, 15(6) (6), 833 - 837, English
- 克誠堂出版, Aug. 2007, Japanese journal of plastic surgery, 50(8) (8), 937 - 942, JapaneseTraumatic CCF in child caused by a chopstick
- 20 Jan. 2007, 日形会誌 : 日本形成外科学会会誌 = Journal of Japan Society of Plastic and Reconstructive Surgery, 27(1) (1), 46 - 50, Japanese痙性麻痺による股関節難治性皮膚潰瘍の治療経験
- 国立病院機構姫路医療センター, 2007, 独立行政法人国立病院機構姫路医療センター紀要, 10, 21 - 24, Japanese心臓手術後の前胸部難治性皮膚潰瘍に対する筋皮弁移植術による治療経験
- 20 Jan. 2003, 日形会誌 : 日本形成外科学会会誌 = Journal of Japan Society of Plastic and Reconstructive Surgery, 23(1) (1), 45 - 50, Japanese巨大皮膚欠損症例に対するVacuum-Assisted Closureによる治療経験
- (NPO)日本口腔科学会, Nov. 2002, 日本口腔科学会雑誌, 51(6) (6), 480 - 480, Japanese
- 20 Sep. 2001, 日形会誌 : 日本形成外科学会会誌 = Journal of Japan Society of Plastic and Reconstructive Surgery, 21(9) (9), 559 - 562, Japanese硬化療法による外耳道化膿性肉芽腫の治療経験
- Contributor, A皮膚皮下/軟部腫瘍 pp14-19、pp24-26, 全日本病院出版会, Sep. 2020, Japanese, ISBN: 9784865192766図解こどものあざとできもの : 診断力を身につける
- Contributor, 3章、Ⅱ.血管奇形、10.顔面部動静脈奇形, 克誠堂出版, Jun. 2020, Japanese, ISBN: 9784771905368もう迷わない血管腫・血管奇形 : 分類・診断と治療・手技のコツ
- Contributor, 克誠堂, 2018, Japanese形成外科治療手技全書 第5巻 腫瘍・母斑・血管奇形 / 第4章4動静脈奇形Scholarly book
- Others, 羊土社, 2017, Japanese皮膚科医・形成外科医のためのレーザー治療スタンダード / 第3章8 毛細血管拡張症の標準的治療Scholarly book
- Others, 羊土社, 2017, Japanese皮膚科医・形成外科医のためのレーザー治療スタンダード / 第1章3 色素レーザーScholarly book
- Others, 南山堂, Sep. 2014, Japaneseまるわかり創傷治療のキホン / 第2章急性創傷 I小外傷 3創傷治療のピットフォールScholarly book
- Others, 南山堂, Sep. 2014, Japaneseまるわかり創傷治療のキホン / 第2章急性創傷 II熱傷 3熱傷局所治療のピットフォールTextbook
- Joint work, 克誠堂出版, Sep. 2012, Japanese創傷のすべて / 第III章 その他の創傷,9. 動静脈奇形による潰瘍Scholarly book
- 第45回日本マイクロサージャリー学会学術集会, Dec. 2018, Japanese, 大阪, Domestic conference指神経背側枝を温存した逆行性指動脈皮弁による指尖部再建の経験Oral presentation
- 第120回関西形成外科学会学術集会, Nov. 2018, Japanese, 西宮, Domestic conference膠原病にPADを合併した難治性足潰瘍に対して腰部交感神経節ブロックを施行し、良好な結果が得られた3症例Oral presentation
- 第120回関西形成外科学会学術集会, Nov. 2018, Japanese, 西宮, Domestic conference食道癌胃管再建術後の膵頭十二指腸切除術において胃管血管茎の血行再建を行った2例Oral presentation
- 第4回日本下肢救済・足病学会関西地方会学術集会, Oct. 2018, Japanese, 大阪, Domestic conference動脈閉塞による虚血を合併する膠原病性潰瘍の治療経験Oral presentation
- 第41回日本美容外科学会総会, Oct. 2018, Japanese, 東京, Domestic conference超音波ガイド下ヒアルロン酸注入法と注入前後のLaser Speckle Flowgraphyによる皮膚血流評価の経験Oral presentation
- 第36回日本頭蓋顎顔面外科学会学術集会, Oct. 2018, Japanese, 札幌, Domestic conference唇裂術後様変形をきたした外傷性上口唇瘢痕拘縮の一例Oral presentation
- 第27回日本形成外科学会基礎学術集会, Oct. 2018, Japanese, 東京, Domestic conference【皮膚軟部腫瘍診療ガイドライン作成部門ガイドラインシンポジウム】 非上皮系良性腫瘍Public symposium
- 第72回東海形成外科学会, Oct. 2018, Japanese, 名古屋, Domestic conference【特別講演】血管腫・血管奇形の診断と治療.~過去20年の経験から~Public discourse
- 第36回日本頭蓋顎顔面外科学会学術集会, Oct. 2018, Japanese, 札幌, Domestic conference【教育パネルディスカッションⅡ「通」シリーズ~重箱のすみまで 2.外傷及び腫瘍切除後の顔面組織の再建:「NPWTを用いた頭皮~顔面・頸部皮膚欠損に対する再建」】開頭後の頭皮・頭蓋欠損に対するNPWTを用いた再建術の限界Others
- 第36回日本頭蓋顎顔面外科学会学術集会, Oct. 2018, Japanese, 札幌, Domestic conference【教育パネルディスカッションII 「通」シリーズ~重箱のすみまで 頭頸部癌の再建治療を行う頭頸部再建外科:Aesthetic mindをそなえた顔面再建~What are the final goals?】がん切除によって生じた顔面の全層欠損に対する再建戦略-Step-Surgery Concept-Others
- 平成30年度厚生労働省科学研究補助金難治性疾患等政策研究事業,第2回市民公開講座, Sep. 2018, Japanese, 松本, Domestic conference脈管奇形Public discourse
- 第10回日本創傷外科学会総会・学術集会, Jul. 2018, Japanese, さいたま, Domestic conference皮膚軟部組織欠損を伴う下腿骨髄炎・感染性偽関節に対するMasquelet法を用いた治療戦略Oral presentation
- 第10回血管腫血管奇形講習会, Jul. 2018, Japanese, 大阪, Domestic conference乳児血管腫・その他の血管性腫瘍Public discourse
- 第34回日本皮膚悪性腫瘍学会学術大会, Jul. 2018, Japanese, 浜松, Domestic conference当科で経験した外陰部悪性黒色腫の2例Oral presentation
- 第15回日本血管腫血管奇形学会学術集会, Jul. 2018, Japanese, 大阪, Domestic conference耳下腺部リンパ管奇形として長年加療を受けていた成熟嚢胞性奇形腫の一例Oral presentation
- 第10回日本創傷外科学会総会・学術集会, Jul. 2018, Japanese, さいたま, Domestic conference高気圧酸素療法が行われた難治性潰瘍35例の検討 ~継続・中止を検討するタイミングに関する分析~Oral presentation
- 第15回日本血管腫血管奇形学会学術集会, Jul. 2018, Japanese, 大阪, Domestic conferenceCLOVES症候群の一症例(第2報)Oral presentation
- 第3回TaKkle in WATER, Jun. 2018, Japanese, 徳島, Domestic conference切除に難渋した下肢巨大神経線維腫の一例Oral presentation
- 第42回日本頭頸部癌学会, Jun. 2018, Japanese, 東京, Domestic conference【シンポジウム8:標準化への挑戦-ビデオから学ぶ施設間の違い-】神戸大学における下顎区域切除後のプレート再建Public symposium
- 第38回日本静脈学会総会, Jun. 2018, Japanese, 横須賀, Domestic conference【シンポジウム4:手術手技ビデオ:経験を宝に】マイクロサージャリーを用いた脈管奇形の手術療法Public symposium
- Scientific Meeting of Infantile hemangioma by Leading Experts 2, May 2018, Japanese, 東京, Domestic conference潰瘍化した乳児血管腫に対するプロプラノロール内服療法の有用性の検討Oral presentation
- 第45回兵庫県形成外科医会研究会, May 2018, Japanese, 神戸, Domestic conference外陰部に発生したaggressive angiomyxomaの1例Oral presentation
- 22nd International Workshop of the International Society for the Study of Vascular Anomalies, May 2018, English, Amsterdam, International conferenceCompartmentalization using barbed sutures in the treatment of infiltrative venous malformations.Oral presentation
- 22nd International Workshop of the International Society for the Study of Vascular Anomalies, May 2018, English, Amsterdam, International conferenceComparison of Percutaneous Polidocanol Injection and Percutaneous Ethanolamine Oleate Injection for the Treatment of Venous Malformations.Oral presentation
- 第61回日本形成外科学会総会・学術集会, Apr. 2018, Japanese, 福岡, Domestic conference乳児血管腫に対してプロプラノール内服療法に加え、手術療法を併用した症例の検討Oral presentation
- 第61回日本形成外科学会総会・学術集会, Apr. 2018, Japanese, 福岡, Domestic conference頭部皮膚潰瘍に対するbipedicle flap法を用いた治療法Oral presentation
- 第61回日本形成外科学会総会・学術集会, Apr. 2018, Japanese, 福岡, Domestic conference当科で経験した外陰部悪性黒色腫の2例Oral presentation
- 第61回日本形成外科学会総会・学術集会, Apr. 2018, Japanese, 福岡, Domestic conference当科でのシリコン乳房インプラント抜去についての検討Oral presentation
- 第61回日本形成外科学会総会・学術集会, Apr. 2018, Japanese, 福岡, Domestic conference足部動静脈奇形による難治性潰瘍の治療経験Oral presentation
- 第61回日本形成外科学会総会・学術集会, Apr. 2018, Japanese, 福岡, Domestic conference術前診断で血管奇形を疑われた2例Oral presentation
- 第61回日本形成外科学会総会・学術集会, Apr. 2018, Japanese, 福岡, Domestic conference手指部に生じた静脈奇形に対する手術療法の検討Oral presentation
- 第61回日本形成外科学会総会・学術集会, Apr. 2018, Japanese, 福岡, Domestic conference眼窩形態の解析研究 ~内壁と下壁のなす角と距離の関係~Oral presentation
- 第61回日本形成外科学会総会・学術集会, Apr. 2018, Japanese, 福岡, Domestic conference【シンポジウム5:心臓血管術後縦隔炎に対するリカバリー】心臓血管術後87例の検討Public symposium
- 第61回日本形成外科学会総会・学術集会, Apr. 2018, Japanese, 福岡, Domestic conference【シンポジウム4:術後または外傷後の四肢骨髄炎に対するリカバリー】当院における下肢骨髄炎の治療経験(術後または外傷後の四肢骨髄炎に対するリカバリー)Public symposium
- 第61回日本形成外科学会総会・学術集会, Apr. 2018, Japanese, 福岡, Domestic conference【シンポジウム16:脳外科術後に生じた硬膜外膿瘍および頭蓋骨欠損に対するリカバリー】 脳外科術後に生じた頭部創傷に対する治療戦略Public symposium
- 第61回日本形成外科学会総会・学術集会, Apr. 2018, Japanese, 福岡, Domestic conferenceレーザースペックルフローグラフィーと血管造影所見を比較した3症例Oral presentation
- 第61回日本形成外科学会総会・学術集会, Apr. 2018, Japanese, 福岡, Domestic conferenceKlippel-Trenaunay症候群に合併したstreptococcal toxic shock syndromeの治療経験Oral presentation
- 第15回日本褥瘡学会近畿地方会学術集会, Mar. 2018, Japanese, 草津, Domestic conference褥瘡治癒後の瘢痕に生じたと考えられる皮膚石灰沈着症の1例Oral presentation
- 第118回関西形成外科学会学術集会, Mar. 2018, Japanese, 大阪, Domestic conference術前に血管奇形が疑われた大腿筋肉内病変の治療経験Oral presentation
- The 18th Kansai Interuniversity Symposium on State-of-the-art in PRS, Feb. 2018, Japanese, 別府, Domestic conference血管奇形の手術療法Oral presentation
- 第44回日本マイクロサージャリー学会学術集会(宮崎), Dec. 2017, Japanese, 日本マイクロサージャリー学会, 宮崎, Domestic conference当科での四肢における遊離皮弁移植の検討.Oral presentation
- 第44回日本マイクロサージャリー学会学術集会(宮崎), Dec. 2017, Japanese, 日本マイクロサージャリー学会, 宮崎, Domestic conference顕微鏡を用いた血管腫・血管奇形の治療経験.Oral presentation
- 第44回日本マイクロサージャリー学会学術集会(宮崎), Dec. 2017, Japanese, 日本マイクロサージャリー学会, 宮崎, Domestic conference【パネルディスカッション2 皮弁・切断指モニタリングのアップデート】当科における移植皮弁モニタリング法の選択 -感度と簡便さを満たす最適な組み合わせとは-.Public symposium
- 第44回日本マイクロサージャリー学会学術集会(宮崎), Dec. 2017, Japanese, 日本マイクロサージャリー学会, 宮崎, Domestic conference【シンポジウム1「神経再建術後に脳の可塑性はあるか?」】神経再建術後に脳の可塑性はあるか?~舌下神経-顔面神経クロスリンク型神経移植術の経験から考察する~.Public symposium
- 第44回日本マイクロサージャリー学会学術集会(宮崎), Dec. 2017, Japanese, 日本マイクロサージャリー学会, 宮崎, Domestic conference2回の遊離皮弁を含む複数回の手術加療を経て治癒した基礎疾患を有する脛骨開放骨折後感染症例の治療経験.Oral presentation
- 第117回関西形成外科学会学術集会(和歌山), Nov. 2017, Japanese, 関西形成外科学会, 和歌山, Domestic conference左中指の腱鞘線維腫の一例.Oral presentation
- 第35回日本頭蓋顎顔面外科学会学術集会(福岡), Nov. 2017, Japanese, 日本頭蓋顎顔面外科学会, 福岡, Domestic conference外斜視を呈した小児眼窩底骨折の一例.Oral presentation
- 第26回日本形成外科学会基礎学術集会(大阪), Oct. 2017, Japanese, 日本形成外科学会, 大阪, Domestic conference動静脈奇形に対するマイクロアレイによる網羅的検討.Oral presentation
- 第3回日本下肢救済・足病学会関西地方会学術集会(奈良), Oct. 2017, Japanese, 日本下肢救済・足病学会関西地方会, 奈良, Domestic conference当院における重症下肢虚血治療中のリハビリテーションの介入状況についての検討.Oral presentation
- 第26回日本形成外科学会基礎学術集会(大阪), Oct. 2017, English, 日本形成外科学会, 大阪, International conference撮影方法に関しての画像の簡易な補正方法に関しての工夫 -テープとマジックを用いて-.Oral presentation
- 第26回日本形成外科学会基礎学術集会(大阪), Oct. 2017, Japanese, 日本形成外科学会, 大阪, Domestic conference【第4回皮膚腫瘍外科分野指導医シンポジウム】外鼻広範囲欠損.Public symposium
- 第5回日本乳房オンコプラスティックサージャリー学会総会(東京), Sep. 2017, Japanese, 日本乳房オンコプラスティックサージャリー学会, 東京, Domestic conference遊離腹部皮弁移植術後に手術療法を要した腹壁ヘルニア症例の検討.Oral presentation
- 第9回血管腫血管奇形講習会(郡山), Jul. 2017, Japanese, 血管腫血管奇形学会, 郡山, Domestic conference乳児血管腫の診断と治療.Public discourse
- 第9回日本創傷外科学会総会・学術集会(岐阜), Jul. 2017, Japanese, 日本創傷外科学会, 岐阜, Domestic conference当科における陰圧閉鎖療法の応用について.Oral presentation
- 第9回日本創傷外科学会総会・学術集会(岐阜), Jul. 2017, Japanese, 日本創傷外科学会, 岐阜, Domestic conference当院における過去3年間で局所陰圧閉鎖療法および限局的洗浄型NPWTを用いた症例の検討.Public symposium
- 第30回日本レーザー医学会関西地方会(神戸), Jul. 2017, Japanese, 日本レーザー医学会, 神戸, Domestic conference色素レーザー照射後に潰瘍を生じた乳児血管腫症例の検討.Oral presentation
- 第116回関西形成外科学会学術集会(大阪), Jul. 2017, Japanese, 関西形成外科学会, 大阪, Domestic conference重度カリフラワー耳に対する肋軟骨移植術の治療経験.Oral presentation
- 第9回日本創傷外科学会総会・学術集会(岐阜), Jul. 2017, Japanese, 日本創傷外科学会, 岐阜, Domestic conference【シンポジウム3「マイクロサージャリーを用いた頭頸部領域の再手術」】頭頸部の既手術部位を遊離皮弁で再建する際の吻合血管選択に関する考察.Public symposium
- 第33回日本皮膚悪性腫瘍学会学術大会(秋田), Jun. 2017, Japanese, 日本皮膚悪性腫瘍学会, 秋田, Domestic conference【腫瘍切除・再建コロシアム1】外鼻広範囲欠損.Public symposium
- 第33回日本皮膚悪性腫瘍学会学術大会(秋田), Jun. 2017, Japanese, 日本皮膚悪性腫瘍学会, 秋田, Domestic conferencePerineural invasion(PNI)を示したCutaneous squamouscell carcinoma(SCC)の4例.Oral presentation
- 9th Congress of World Society for Reconstructive Microsurgery(Seoul), Jun. 2017, Japanese, World Society for Reconstructive Microsurgery, Seoul, Domestic conferenceFree Latissimus Dorsi Musculocutaneous Flap for Pelvic Floor Reconstruction Following.Pelvic Exenteration.Oral presentation
- 第9回日本下肢救済・足病学会学術集会(福岡), May 2017, Japanese, 日本下肢救済・足病学会, 福岡, Domestic conference重症下肢虚血患者が入院治療中に悪性腫瘍の診断に至った3例の経験.Oral presentation
- 第60回日本形成外科学会総会・学術集会(大阪), Apr. 2017, Japanese, 日本形成外科学会, 大阪, Domestic conference不全切断指の血行評価にICG蛍光造影法を用いた3例.Oral presentation
- 第60回日本形成外科学会総会・学術集会(大阪), Apr. 2017, Japanese, 日本形成外科学会, 大阪, Domestic conference当科で経験したTufted angiomaの4例.Oral presentation
- 第60回日本形成外科学会総会・学術集会(大阪), Apr. 2017, Japanese, 日本形成外科学会, 大阪, Domestic conference当院における坐骨部褥瘡に対する外科的治療の経験.Oral presentation
- 第60回日本形成外科学会総会・学術集会(大阪), Apr. 2017, Japanese, 日本形成外科学会, 大阪, Domestic conference高気圧酸素療法が行われた難治性潰瘍25例の検討 ~治療効果に対する影響因子の分析~.Oral presentation
- 第60回日本形成外科学会総会・学術集会(大阪), Apr. 2017, Japanese, 日本形成外科学会, 大阪, Domestic conference感染した植込み型デバイス抜去後の創傷管理についての検討-持続洗浄型局所陰圧閉鎖療法を中心に-.Oral presentation
- 第60回日本形成外科学会総会・学術集会(大阪), Apr. 2017, Japanese, 日本形成外科学会, 大阪, Domestic conference【シンポジウム5 血管奇形:自験例から見た「良い」「悪い」部分切除の条件】当科における血管奇形の部分切除の戦略と工夫 -脈管の構成要素に応じた手術術式-.Public symposium
- 第60回日本形成外科学会総会・学術集会(大阪), Apr. 2017, Japanese, 日本形成外科学会, 大阪, Domestic conference【シンポジウム2「頭頸部再建に残された課題-二次再建の挑戦と課題-」】重症下顎骨放射線骨髄炎に対する手術―デブリドマン範囲を病理組織学的検討結果から考察する―.Public symposium
- 第60回日本形成外科学会総会・学術集会(大阪), Apr. 2017, English, 日本形成外科学会, 大阪, 韓国, International conferenceブーメラン型有茎広背筋皮弁で閉鎖した慢性膿胸の2例.Oral presentation
- 第15回日本フットケア学会年次学術集会(岡山), Mar. 2017, Japanese, 日本フットケア学会, 岡山, Domestic conference当院での糖尿病性足病変における足関節可動域制限と潰瘍発症との関連についての検討.Oral presentation
- 第22回日本形成外科手術手技学会(東京), Feb. 2017, Japanese, 日本形成外科手術手技学会, 東京, Domestic conference不全切断指の血行評価にICG蛍光造影法を用いた1例.Oral presentation
- 第43回日本マイクロサージャリー学会学術集会, Nov. 2016, Japanese, 日本マイクロサージャリー学会学術集会, 広島市, Domestic conference複数の不全切断指の血行評価にICG蛍光造影法を用いた1例Oral presentation
- 第114回関西形成外科学会学術集会, Nov. 2016, Japanese, 関西形成外科学会学術集会, 高槻市, Domestic conference節外性NK/T細胞リンパ腫鼻型の内科的治療後の外鼻変形に対して再建を要した1例Oral presentation
- 第114回関西形成外科学会学術集会, Nov. 2016, Japanese, 関西形成外科学会学術集会, 高槻市, Domestic conference神経浸潤のみを認め手術を繰り返した鼻根部再発有棘細胞癌の一例Oral presentation
- 第44回日本マイクロサージャリー学会学術集会, Nov. 2016, Japanese, 日本マイクロサージャリー学会学術集会, 広島市, Domestic conference術後血流不全により緊急再開創術を要した遊離空腸移植症例の検討Oral presentation
- 第47回日本マイクロサージャリー学会学術集会, Nov. 2016, Japanese, 日本マイクロサージャリー学会学術集会, 広島市, Domestic conference骨盤内臓全摘後に遊離広背筋皮弁移植による会陰部再建術を行った症例の検討Oral presentation
- 第114回関西形成外科学会学術集会, Nov. 2016, Japanese, 関西形成外科学会学術集会, 高槻市, Domestic conference関節リウマチ患者の慢性創傷における治療方針決定因子についての検討Oral presentation
- 第48回日本マイクロサージャリー学会学術集会, Nov. 2016, Japanese, 日本マイクロサージャリー学会学術集会, 広島市, Domestic conference【ビデオシンポジウム 皮弁移植術を極める】当科における遊離前腕皮弁移植を用いた再建戦略[Invited]Nominated symposium
- 第34回日本頭蓋顎顔面外科学会学術集会, Nov. 2016, Japanese, 日本頭蓋顎顔面外科学会学術集会, 東京都, Domestic conferenceレックリングハウゼン病の下眼瞼外反に対し耳介軟骨移植とCaraji anchor suture systemで吊上げを行った1例Oral presentation
- 第37回日本レーザー医学会総会, Oct. 2016, Japanese, 日本レーザー医学会総会, 旭川市, Domestic conference治療抵抗性毛細血管奇形に対するパルス可変式色素レーザー・Nd:YAGレーザー併用療法の検討Oral presentation
- 第25回日本形成外科学会基礎学術集会, Sep. 2016, Japanese, 日本形成外科学会基礎学術集会, 大阪市, Domestic conference【パネルディスカッション3.血管治療の基礎から臨床へ】動静脈奇形の増殖機序に関する検討[Invited]Nominated symposium
- 第8回日本創傷外科学会総会・学術集会, Jul. 2016, Japanese, 日本創傷外科学会総会・学術集会, 東京都, Domestic conference踵骨骨髄炎に対し創内持続陰圧洗浄療法を用いて治療した3例Oral presentation
- 第113回関西形成外科学会学術集会, Jul. 2016, Japanese, 関西形成外科学会学術集会, 大阪市, Domestic conferencePeripherally Inserted Central Catheter(PICC) 挿入時にガイドワイヤーの一部が遺残し、腱内に迷入していた1症例Oral presentation
- 第32回日本皮膚悪性腫瘍学会学術大会, May 2016, Japanese, 日本皮膚悪性腫瘍学会, 鹿児島, Domestic conference膝窩リンパ節転移を認めた母趾悪性黒色腫の一例Oral presentation
- 第32回日本皮膚悪性腫瘍学会学術大会, May 2016, Japanese, 日本皮膚悪性腫瘍学会学術大会, 鹿児島市, Domestic conference皮膚切除を伴う骨盤内臓全摘後に遊離広背筋皮弁移植による再建術を行った症例の検討Oral presentation
- 第32回日本皮膚悪性腫瘍学会学術大会, May 2016, Japanese, 日本皮膚悪性腫瘍学会学術大会, 鹿児島市, Domestic conference当科における皮膚悪性腫瘍切除後の外鼻再建に対する検討Oral presentation
- 第13回日本血管腫血管奇形学会, May 2016, Japanese, 日本血管腫血管奇形学会, 石垣市, Domestic conference【ランチョンセミナー】乳児血管腫の病態と治療Public discourse
- 第13回日本血管腫血管奇形学会, May 2016, Japanese, 日本血管腫血管奇形学会, 石垣市, Domestic conferenceCLOVES syndromeが疑われた症例の経験Oral presentation
- 第59回日本形成外科学会総会・学術集会, Apr. 2016, Japanese, 日本形成外科学会総会・学術集会, 福岡市, Domestic conference流出型神経端側縫合を利用する腫瘍切除後顔面神経即時再建-同一施設における連続20症例の検討-Oral presentation
- 第59回日本形成外科学会総会・学術集会, Apr. 2016, Japanese, 日本形成外科学会総会・学術集会, 福岡市, Domestic conference当院で経験した踵骨骨髄炎の9例Oral presentation
- 第59回日本形成外科学会総会・学術集会, Apr. 2016, Japanese, 日本形成外科学会総会・学術集会, 福岡市, Domestic conference洗浄型NPWTを用いた下肢骨髄炎の検討Oral presentation
- 第59回日本形成外科学会総会・学術集会, Apr. 2016, Japanese, 日本形成外科学会総会・学術集会, 福岡市, Domestic conference仙腸骨部慢性放射線性潰瘍の治療経験Oral presentation
- 第59回日本形成外科学会総会・学術集会, Apr. 2016, Japanese, 日本形成外科学会総会・学術集会, 福岡市, Domestic conference静脈奇形に対する硬化療法におけるオレイン酸モノエタノールアミンとポリドカノールの比較検討Oral presentation
- 第59回日本形成外科学会総会・学術集会, Apr. 2016, Japanese, 日本形成外科学会総会・学術集会, 福岡市, Domestic conference青色ゴム球様母斑症候群の治療経験Oral presentation
- 第59回日本形成外科学会, Apr. 2016, Japanese, 日本形成外科学会, 福岡, Domestic conference食道癌術後胃管気管支瘻に対して有茎広背筋弁を用いて閉鎖した1例Oral presentation
- 第59回日本形成外科学会総会・学術集会, Apr. 2016, Japanese, 日本形成外科学会総会・学術集会, 福岡市, Domestic conference眼瞼部基底細胞癌の部位別組織像と切除法の検討Oral presentation
- 第59回日本形成外科学会総会・学術集会, Apr. 2016, Japanese, 日本形成外科学会総会・学術集会, 福岡市, Domestic conference我々の乳児血管腫に対する治療方針(プロプラノロール内服単独とレーザーおよび手術併用療法について)Oral presentation
- 第59回日本形成外科学会総会・学術集会, Apr. 2016, Japanese, 日本形成外科学会総会・学術集会, 福岡市, Domestic conference異所性蒙古斑のレーザー治療後の色素沈着に対する工夫と経過Oral presentation
- 第59回日本形成外科学会総会・学術集会, Apr. 2016, Japanese, 日本形成外科学会総会・学術集会, 福岡市, Domestic conference【シンポジウム5.動静脈奇形の最新治療:手術,塞栓,硬化療法】動静脈奇形に対する集学的治療 ~手術療法を成功に導く最新治療コンセプト~[Invited]Nominated symposium
- 第112回関西形成外科学会学術集会, Mar. 2016, Japanese, 関西形成外科学会学術集会, 枚方市, Domestic conference骨盤内臓全摘術後に有茎大網弁及び遊離広背筋充填術を施行した一例Oral presentation
- 第21回日本形成外科手術手技学会, Feb. 2016, Japanese, 日本形成外科手術手技学会, さいたま市, Domestic conference食道癌術後胃管気管支瘻に対して有茎広背筋弁を用いて閉鎖した1例Oral presentation
- 第27回日本眼瞼義眼床手術学会, Feb. 2016, Japanese, 日本眼瞼義眼床手術学会, 横浜市, Domestic conference【特別企画「眼窩骨折の治療指針」】神戸大学形成外科における眼窩骨折の治療[Invited]Invited oral presentation
- 第42回日本マイクロサージャリー学会学術集会, Nov. 2015, Japanese, 日本マイクロサージャリー学会学術集会, さいたま市, Domestic conference無侵襲混合血酸素飽和度監視システム:INVOSを用いた遊離皮弁術後モニタリングOral presentation
- 第24回日本形成外科学会 基礎学術集会, Oct. 2015, Japanese, 日本形成外科学会 基礎学術集会, 盛岡市, Domestic conference動静脈奇形の増殖機序に関する検討【第2報】-成長ホルモン受容体を巡って-Oral presentation
- 第3回日本乳房オンコプラスティックサージャリー学会総会, Sep. 2015, Japanese, 日本乳房オンコプラスティックサージャリー学会総会, 札幌市, Domestic conference常勤形成外科医不在施設における乳房一次再建症例の検討Oral presentation
- 第31回日本皮膚悪性腫瘍学会学術大会, Jul. 2015, Japanese, 日本皮膚悪性腫瘍学会学術大会, 大阪市, Domestic conference【シンポジウム3.皮膚悪性腫瘍に対する外科治療の現状とこれから】顔面基底細胞癌に対する外科治療~切除と再建を両立させる方策~[Invited]Nominated symposium
- 第12回血管腫血管奇形学会, Jul. 2015, Japanese, 血管腫血管奇形学会, 東京都, Domestic conference【アフタヌーンセミナー】表在性血管腫・血管奇形に対する色素レーザー治療Public discourse
- 4th Congress of Asian Society of Head and Neck Oncology, Jun. 2015, English, 日本頭頚部癌学会, 神戸, International conferenceEffectiveness of lymphography for lymphatic leakage after neck dissectionPoster presentation
- 第52回日本小児外科学会学術集会, May 2015, Japanese, 日本小児外科学会学術集会, 神戸市, Domestic conference【ランチョンセミナー】小児における創傷のtotal management~よりよい創傷治癒を実現するための原理原則~Public discourse
- 第58回日本形成外科学会総会・学術集会, Apr. 2015, Japanese, 日本形成外科学会総会・学術集会, 京都市, Domestic conference当科における転移性皮膚腫瘍の統計と治療Oral presentation
- 第58回日本形成外科学会総会・学術集会, Apr. 2015, Japanese, 日本形成外科学会総会・学術集会, 京都市, Domestic conference常勤形成外科不在施設における自家組織を用いた乳房一次再建Oral presentation
- 第58回日本形成外科学会総会・学術集会, Apr. 2015, Japanese, 日本形成外科学会総会・学術集会, 京都市, Domestic conference【第2回皮膚腫瘍外科分野指導医シンポジウム Oncoplastic Skin Surgery ~私ならこう治す!】外鼻皮膚腫瘍に対するtotal management[Invited]Nominated symposium
- 第58回日本形成外科学会総会・学術集会, Apr. 2015, Japanese, 日本形成外科学会総会・学術集会, 京都市, Domestic conference【ランチョンセミナー1.変わるレーザー治療 ~リスクが少ない治療へのシフト~】今さら聞けないQスイッチアレックスレーザーのキホンPublic discourse
- 第109回関西形成外科学会学術集会, Mar. 2015, Japanese, 関西形成外科学会, 京都, Domestic conference難治性下腿潰瘍の一例Oral presentation
- 第20回日本形成外科手術手技学会, Feb. 2015, Japanese, 日本形成外科手術手技学会, 鎌倉, Domestic conference自家組織を用いた乳房二次再建における紙粘土による簡便なシミュレーション法Oral presentation
- 第41回日本マイクロサージャリー学会学術集会, Dec. 2014, Japanese, 日本マイクロサージャリー学会, 京都, Domestic conference複数回の化学放射線療法を施行された多重癌患者に対する遊離広背筋皮弁を用いた頭蓋再建の経験Oral presentation
- 第41回日本マイクロサージャリー学会学術集会, Dec. 2014, Japanese, 日本マイクロサージャリー学会, 京都, Domestic conference海洋外傷により受傷した重度下腿開放骨折に対して、遊離広背筋皮弁により再建を行った1例Oral presentation
- 第108回関西形成外科学会学術集会, Dec. 2014, Japanese, 関西形成外科学会, 大阪, Domestic conference下肢血管造影検査後に手指壊疽を起こしたBuerger病の1例Oral presentation
- 第41回日本マイクロサージャリー学会学術集会, Dec. 2014, Japanese, 日本マイクロサージャリー学会, 京都, Domestic conference悪性腫瘍切除後に生じた胸腹壁欠損に対する再建術式の検討Oral presentation
- 第41回日本マイクロサージャリー学会学術集会, Dec. 2014, Japanese, 日本マイクロサージャリー学会, 京都, Domestic conference【シンポジウム1.リンパ浮腫治療におけるマイクロサージャリー】直針付き縫合糸を用いるback-wall techniqueの微小リンパ管吻合における有用性[Invited]Nominated symposium
- 第23回日本形成外科学会基礎学術集会, Oct. 2014, Japanese, 日本形成外科学会, 松本, Domestic conference動静脈奇形の増殖機序に関する検討-成長ホルモン受容体を巡って-Oral presentation
- 第107回関西形成外科学会・第49回中部形成外科学会合同学術集会, Jul. 2014, Japanese, 関西形成外科学会・中部形成外科学会, 加賀, Domestic conference吻合静脈閉塞も生存した遊離空腸パッチの一症例Oral presentation
- 第30回日本皮膚悪性腫瘍学会学術大会, Jul. 2014, Japanese, 日本皮膚悪性腫瘍学会, 東京, Domestic conference肺癌後頭部転移の2症例Oral presentation
- 第30回日本皮膚悪性腫瘍学会学術大会, Jul. 2014, Japanese, 日本皮膚悪性腫瘍学会, 東京, Domestic conference腫瘍切除後に生じた胸腹壁欠損に対する再建手術の検討Oral presentation
- 第6回日本創傷外科学会総会・学術集会, Jul. 2014, Japanese, 日本創傷外科学会, 高松, Domestic conference【イブニングセミナー2.Next Patient oriented Wound Therapy~次世代の患者本位の創傷治療~】局所陰圧閉鎖療法の変遷~「壁吸引」から「SNaP陰圧閉鎖療法システム」へ~Public discourse
- 第107回関西形成外科学会・第49回中部形成外科学会合同学術集会, Jul. 2014, Japanese, 関西形成外科学会・中部形成外科学会, 加賀, Domestic conferenceリピオドールによるリンパ管造影にて治癒を得た鼠径リンパ節郭清後リンパ漏の1例Oral presentation
- 第57回日本形成外科学会総会・学術集会, Apr. 2014, Japanese, 日本形成外科学会, 長崎, Domestic conference乳児血管腫に対する色素レーザー治療の検討~Vbeam は従来型ダイレーザーよりも退縮時期を早めるか?~Oral presentation
- 第57回日本形成外科学会総会・学術集会, Apr. 2014, Japanese, 日本形成外科学会, 長崎, Domestic conference動静脈奇形に対する集学的治療の適応と限界Oral presentation
- 第57回日本形成外科学会総会・学術集会, Apr. 2014, Japanese, 日本形成外科学会, 長崎, Domestic conference当院における胸壁・腹壁全層欠損の治療法についての検討Oral presentation
- 第57回日本形成外科学会総会・学術集会, Apr. 2014, Japanese, 日本形成外科学会, 長崎, Domestic conference開頭術後頭部人工物露出症例の原因に関する検討とその対策Oral presentation
- 第57回日本形成外科学会総会・学術集会, Apr. 2014, Japanese, 日本形成外科学会, 長崎, Domestic conference【特別企画 第1回皮膚腫瘍外科指導専門医シンポジウム"Unfavorable result cases~明日の治療に向けて~"】3-1:皮膚腫瘍外科における unfavorable result cases の分類 何が unfavorable なのか?[Invited]Nominated symposium
- ISSVA 20th International Workshop on Vascular Anomalies, Apr. 2014, English, ISSVA 20th International Workshop on Vascular Anomalies, Melbourne, Australia, International conferenceImportance of the control of sclerosant egress on the sclerotherapy for venous malformationsOral presentation
- 第57回日本形成外科学会総会・学術集会, Apr. 2014, Japanese, 日本形成外科学会, 長崎, Domestic conferenceCalvarial radionecrosisOral presentation
- 第57回日本形成外科学会総会・学術集会, Apr. 2014, Japanese, 日本形成外科学会, 長崎, Domestic conferenceBuerger 病による手指壊疽に対するDistal Venous Arterialization の一例Oral presentation
- 第57回日本手外科学会学術集会, Apr. 2014, Japanese, 日本手外科学会, 宜野湾, Domestic conferenceBuerger 病による手指壊疽に対するDistal Venous Arterializationの一例Oral presentation
- 第19回日本形成外科手術手技学会, Feb. 2014, Japanese, 日本形成外科手術手技学会, 愛知, Domestic conferenceパネルディスカッション3. ビデオで伝えたい私の手順Public discourse
- 第105回関西形成外科学会学術集会, Dec. 2013, Japanese, 関西形成外科学会学術集会, 大阪市, Domestic conference頭頸部再建術後に仮性動脈瘤を生じた一例.Oral presentation
- 第105回関西形成外科学会学術集会, Dec. 2013, Japanese, 関西形成外科学会学術集会, 大阪市, Domestic conference胃癌術後の腹壁再発切除術により生じた 胸腹壁欠損に対する治療経験Oral presentation
- 第23回日本シミュレーション外科学会, Nov. 2013, Japanese, 日本シミュレーション外科学会, 福岡市, Domestic conference血管奇形に対するエコーガイド下硬化療法の経験 ~有用性と問題点について~.Oral presentation
- 第31回日本頭蓋顎顔面外科学会学術集会, Oct. 2013, Japanese, 日本頭蓋顎顔面外科学会学術集会, 名古屋市, Domestic conference開頭術後頭部皮膚潰瘍の原因に関する検討とその対策.Oral presentation
- 第40回日本マイクロサージャリー学会学術集会, Sep. 2013, Japanese, 日本マイクロサージャリー学会学術集会, 盛岡市, Domestic conference遊離皮弁による頭蓋再建症例の検討.Oral presentation
- 第40回日本マイクロサージャリー学会学術集会, Sep. 2013, Japanese, 日本マイクロサージャリー学会学術集会, 盛岡市, Domestic conference脳外科術後SSIにおけるICG蛍光造影の有用性-腐骨の評価-.Oral presentation
- 第40回日本マイクロサージャリー学会学術集会, Sep. 2013, Japanese, 日本マイクロサージャリー学会学術集会, 盛岡市, Domestic conference【パネルディスカッション3-I.移植皮弁の選択 私のファーストチョイス-足部・下腿に用いる皮弁-】Contourを重視した足部および下腿遠位部の再建法.[Invited]Nominated symposium
- 第40回日本マイクロサージャリー学会学術集会, Sep. 2013, Japanese, 日本マイクロサージャリー学会学術集会, 盛岡市, Domestic conference【パネルディスカッション1.血管吻合術後の管理と移植組織サルベージ法の実際】多様な血管吻合術後皮弁モニタリング.[Invited]Nominated symposium
- 第40回日本マイクロサージャリー学会学術集会, Sep. 2013, Japanese, 日本マイクロサージャリー学会学術集会, 盛岡市, Domestic conference【シンポジウム2.知覚皮弁の適応と成績】皮弁と知覚に関する経験と考察.[Invited]Nominated symposium
- 第29回日本皮膚悪性腫瘍学会学術大会, Aug. 2013, Japanese, 日本皮膚悪性腫瘍学会学術大会, 甲府市, Domestic conference腹腔内へ広範囲に浸潤した腹直筋内low-grade myofibrosarcomaの治療経験.Oral presentation
- 第37回日本頭頸部癌学会, Jun. 2013, Japanese, 日本頭頸部癌学会, 東京都, Domestic conferenceがん切除後下顎再建における再建理論「CATコンセプト」.Oral presentation
- 第56回日本形成外科学会総会・学術集会, Apr. 2013, Japanese, 日本形成外科学会総会・学術集会, 東京都, Domestic conference苺状血管腫に対するレーザー照射後に潰瘍を形成した症例の検討.Oral presentation
- 第56回日本形成外科学会総会・学術集会, Apr. 2013, Japanese, 日本形成外科学会総会・学術集会, 東京都, Domestic conference鼻骨骨折整復固定術における術中エコーの有用性の検討.Oral presentation
- 第56回日本形成外科学会総会・学術集会, Apr. 2013, Japanese, 日本形成外科学会総会・学術集会, 東京都, Domestic conference当科における頭蓋再建の治療方針~シャントと術後合併症との検討~.Oral presentation
- 第56回日本形成外科学会総会・学術集会, Apr. 2013, Japanese, 日本形成外科学会総会・学術集会, 東京都, Domestic conference硬化療法施行後に、縮小することなく疼痛が改善された静脈奇形症例の検討.Oral presentation
- 第56回日本形成外科学会総会・学術集会, Apr. 2013, Japanese, 日本形成外科学会総会・学術集会, 東京都, Domestic conference【ミニシンポジウム11.頭頸部再建における周術期合併症】当院における頭頸部再建術後の安静期間と周術期合併症に関する検討.[Invited]Nominated symposium
- 第56回日本形成外科学会総会・学術集会, Apr. 2013, Japanese, 日本形成外科学会総会・学術集会, 東京都, Domestic conferenceシリコーンゲルドレッシング「エスアイエイドⓇ」を用いた tie over 法の一工夫.Oral presentation
- 第103回関西形成外科学会学術集会, Mar. 2013, Japanese, 関西形成外科学会学術集会, 大阪市, Domestic conference皮膚悪性腫瘍切除後に生じた眼角部上下眼瞼皮膚欠損に対するExtended V-Y flapの有用性に関する検討.Oral presentation
- 第18回日本形成外科手術手技学会, Feb. 2013, Japanese, 日本形成外科手術手技学会, 東京都, Domestic conference乳児血管腫対する病変内切除の有用性.Oral presentation
- 第18回日本形成外科手術手技学会, Feb. 2013, Japanese, 日本形成外科手術手技学会, 東京都, Domestic conferenceCATコンセプトによる下顎再建の実践.Oral presentation
- 第31回日本口腔腫瘍学会総会, Jan. 2013, Japanese, 日本口腔腫瘍学会, 東京, Domestic conference特異的な治癒様相を呈した遊離腓骨による下顎区域再建の1例Oral presentation
- 第39回日本マイクロサージャリー学会学術集会, Dec. 2012, Japanese, 日本マイクロサージャリー学会, 北九州, Domestic conference遊離皮弁を用いた頭頸部再建症例における周術期抗凝固療法の合併症について-VTE予防の観点から-Oral presentation
- 第39回日本マイクロサージャリー学会学術集会, Dec. 2012, Japanese, 日本マイクロサージャリー学会, 北九州, Domestic conference遊離鼠径皮弁により前足部再建を行なった2例Oral presentation
- 第39回日本マイクロサージャリー学会学術集会, Dec. 2012, Japanese, 日本マイクロサージャリー学会, 北九州, Domestic conference乳び胸水に対するリピオドールリンパ管造影法による治療法の検討Oral presentation
- 第39回日本マイクロサージャリー学会学術集会, Dec. 2012, Japanese, 日本マイクロサージャリー学会, 北九州, Domestic conference後期高齢者に対するマイクロサージャリーは危険か?Oral presentation
- 第39回日本マイクロサージャリー学会学術集会, Dec. 2012, Japanese, 日本マイクロサージャリー学会, 北九州, Domestic conferenceリンパ管静脈吻合手技を容易にするためのアイデアと工夫[Invited]Nominated symposium
- 第102回日本形成外科学会関西支部学術集会, Dec. 2012, Japanese, 日本形成外科学会関西支部, 神戸, Domestic conferenceNF1 患者の坐骨神経に発生したMPNST の1 例 ~大腿切断時の腫瘍摘出の観点から~Oral presentation
- 第39回日本マイクロサージャリー学会学術集会, Dec. 2012, Japanese, 日本マイクロサージャリー学会, 北九州, Domestic conference3D-CTA像の体表への投射を利用した血管マーキングOral presentation
- 第30回日本頭蓋顎顔面外科学会学術集会, Nov. 2012, Japanese, 日本頭蓋顎顔面外科学会, 大阪, Domestic conference陳旧性眼窩骨折の治療アルゴリズム[Invited]Nominated symposium
- 第33回日本レーザー医学会総会, Nov. 2012, Japanese, 日本レーザー医学会, 吹田, Domestic conference短パルス色素レーザー照射後に潰瘍を生じた乳児血管腫症例の検討Oral presentation
- 第33回日本レーザー医学会総会, Nov. 2012, Japanese, 日本レーザー医学会, 吹田, Domestic conference赤唇部の毛細血管奇形(単純性血管腫)に対するパルス色素レーザー照射効果の検討Oral presentation
- 第4回日本創傷外科学会総会・学術集会, Jul. 2012, Japanese, 日本創傷外科学会, 福岡, Domestic conference頭蓋再建術後、VPシャントチューブを介して腹膜炎を合併し、その後に硬膜下膿瘍が顕在化した一例Oral presentation
- 第28回日本皮膚悪性腫瘍学会学術大会, Jun. 2012, Japanese, 日本皮膚悪性腫瘍学会, 札幌, Domestic conference外科的治療を行った肺癌頭頸部転移症例の検討Oral presentation
- 第55回日本形成外科学会総会・学術集会, Apr. 2012, Japanese, 日本形成外科学会, 東京, Domestic conference鼻骨骨折における術後外観に影響を与える因子の検討Oral presentation
- 第55回日本形成外科学会総会・学術集会, Apr. 2012, Japanese, 日本形成外科学会, 東京, Domestic conference当院でのリンパ管奇形に対する治療効果の検討Oral presentation
- 第55回日本形成外科学会総会・学術集会, Apr. 2012, Japanese, 日本形成外科学会, 東京, Domestic conference前足部壊死性筋膜炎11例の検討 ―部位と治癒期間との関連―Oral presentation
- 第55回日本形成外科学会総会・学術集会, Apr. 2012, Japanese, 日本形成外科学会, 東京, Domestic conference手術療法を行った乳児血管腫の検討 ~病変内切除の有用性について~Oral presentation
- 第55回日本形成外科学会総会・学術集会, Apr. 2012, Japanese, 日本形成外科学会, 東京, Domestic conferenceFocal typeの静脈奇形はinfiltrative typeよりも硬化療法が効きやすいか? ~同一術者、硬化剤による検討~Oral presentation
- 第100回日本形成外科学会 関西支部, Mar. 2012, Japanese, 日本形成外科学会, 大阪, Domestic conference当科における静脈奇形に対する手術治療の経験Oral presentation
- 第100回日本形成外科学会 関西支部, Mar. 2012, Japanese, 日本形成外科学会, 大阪, Domestic conferenceプロプラノロール投与後に外科的切除を行った乳児血管腫の一例Oral presentation
- 第99回日本形成外科学会 関西支部学術集会, Dec. 2011, Japanese, 日本形成外科学会, 京都, Domestic conference両側眼窩内腫瘍の1例Oral presentation
- 第99回日本形成外科学会 関西支部学術集会, Dec. 2011, Japanese, 日本形成外科学会, 京都, Domestic conference乳輪下膿瘍の3例Oral presentation
- 第38回日本マイクロサージャリー学会学術集会, Nov. 2011, Japanese, 日本マイクロサージャリー学会学術集会, 新潟, Domestic conference当院での遊離下腹部皮弁による乳房再建におけるMDCTを用いた術前Planningの実際Oral presentation
- (社)日本形成外科学会 九州支部学術集会 第87回例会, Oct. 2011, Japanese, 日本形成外科学会, 大分, Domestic conference手術療法を行った乳児血管腫の検討Oral presentation
- 第20回日本形成外科学会基礎学術集会, Oct. 2011, Japanese, 日本形成外科学会, 東京, Domestic conferenceヒトリンパ管におけるプロスタノイドレセプターの発現Oral presentation
- 第98回日本形成外科学会 関西支部学術集会, Jul. 2011, Japanese, 日本形成外科学会, 大阪, Domestic conference心不全が原因と考えられるpunch out型下腿潰瘍の2例Oral presentation
- 第3回日本創傷外科学会総会・学術集会, Jul. 2011, Japanese, 日本創傷外科学会, 札幌, Domestic conferenceComa blister4症例の治療経験Oral presentation
- 第27回日本皮膚悪性腫瘍学会学術大会, Jun. 2011, Japanese, 日本皮膚悪性腫瘍学会, 東京, Domestic conference眼瞼悪性腫瘍切除後欠損に対する再建術式の検討Oral presentation
- 第54回日本形成外科学会総会・学術集会, Apr. 2011, Japanese, 日本形成外科学会総会, 徳島, Domestic conference鼻骨骨折における鼻中隔(鼻中隔軟骨, 篩骨垂直板, 鋤骨)整復の重要性Oral presentation
- 第54回日本形成外科学会総会・学術集会, Apr. 2011, Japanese, 日本形成外科学会総会, 徳島, Domestic conference頭部皮膚潰瘍に対する再建術式の検討Oral presentation
- 第54回日本形成外科学会総会・学術集会, Apr. 2011, Japanese, 日本形成外科学会総会, 徳島, Domestic conference虚血性心疾患を有する患者に対する遊離組織移植術の経験Oral presentation
- 第96回日本形成外科学会関西支部学術集会, Dec. 2010, Japanese, 日本形成外科学会関西支部学術集会, 大阪, Domestic conferenceextended V-Y flapにより内眼角部皮膚欠損を再建した2例Oral presentation
- 第37回日本マイクロサージャリー学会学術集会, Nov. 2010, Japanese, 日本マイクロサージャリー学会学術集会, 名古屋, Domestic conference新しい皮弁血流モニター法~INVOS:無侵襲混合血酸素飽和度監視装置を用いて~第2報Oral presentation
- 第37回日本マイクロサージャリー学会学術集会, Nov. 2010, Japanese, 日本マイクロサージャリー学会学術集会, 名古屋, Domestic conference広背筋皮弁を用いたcross-leg free flapにより下腿再建を行った2症例の経験Oral presentation
- 第28回日本頭蓋顎顔面外科学会学術集会, Oct. 2010, Japanese, 日本頭蓋顎顔面外科学会学術集会, 京都, Domestic conference頭部チタンメッシュ露出症例に対する再建の経験Oral presentation
- 第19回日本形成外科学会基礎学術集会, Sep. 2010, Japanese, 日本形成外科学会基礎学術集会, 横浜, Domestic conference無血清HFDM-1に脂肪酸を添加した培地での培養線維芽細胞の検討 ~安全な培養細胞注入を目指して~Oral presentation
- 第12回日本褥瘡学会学術集会, Aug. 2010, Japanese, 日本褥瘡学会学術集会, 千葉, Domestic conference重度褥瘡(潰瘍)をどこで診る?~褥瘡(潰瘍)ターミナルを取り巻く問題点~Oral presentation
- 第95回日本形成外科学会関西支部学術集会, Jul. 2010, Japanese, 日本形成外科学会関西支部学術集会, 大阪, Domestic conference肘部褥瘡の2例Oral presentation
- 第2回日本創傷外科学会総会・学術集会, Jul. 2010, Japanese, 日本創傷外科学会総会・学術集会, 神戸, Domestic conference肘部褥瘡の2例Oral presentation
- 第95回日本形成外科学会関西支部学術集会, Jul. 2010, Japanese, 日本形成外科学会関西支部学術集会, 大阪, Domestic conference左足底に生じた石灰化腱膜線維腫の一例Oral presentation
- 第2回日本創傷外科学会総会・学術集会, Jul. 2010, Japanese, 日本創傷外科学会総会・学術集会, 神戸, Domestic conferenceけがの手当て ~早くきれいに治すには~Oral presentation
- 第26回日本皮膚悪性腫瘍学会学術大会, Jun. 2010, Japanese, 日本皮膚悪性腫瘍学会学術大会, 東京, Domestic conference鼻腔裏打ち再建の経験Oral presentation
- 第53回日本形成外科学会総会・学術集会, Apr. 2010, Japanese, 日本形成外科学会総会・学術集会, 金沢, Domestic conference当科における肋軟骨炎の治療経験Oral presentation
- 第53回日本形成外科学会総会・学術集会, Apr. 2010, Japanese, 日本形成外科学会総会・学術集会, 金沢, Domestic conference新しい皮弁血流モニター法~INVOS:無侵襲混合血酸素飽和度監視装置を用いて~Oral presentation
- 第53回日本形成外科学会総会・学術集会, Apr. 2010, Japanese, 日本形成外科学会総会・学術集会, 金沢, Domestic conference血管腫の治療Public symposium
- 第53回日本形成外科学会総会・学術集会, Apr. 2010, Japanese, 日本形成外科学会総会・学術集会, 金沢, Domestic conference外鼻全層欠損における鼻腔裏打ち再建の経験Oral presentation
- 第53回日本形成外科学会総会・学術集会, Apr. 2010, Japanese, 日本形成外科学会総会・学術集会, 金沢, Domestic conferenceCystic typeの静脈奇形に対する治療法選択の検討 ~切除術?硬化療法?~Oral presentation
- 第32回兵庫県形成外科医会研究会, Nov. 2009, Japanese, 兵庫県形成外科医会研究会, 神戸, Domestic conference特異な経過をたどった眼窩腫瘍の一例Oral presentation
- 第36回日本マイクロサージャリー学会学術集会, Oct. 2009, Japanese, 日本マイクロサージャリー学会, 徳島, Domestic conference遊離皮弁術後モニタリングとしての無侵襲混合血酸素飽和度監視装置(INVOS5100C)の可能性.Oral presentation
- 第6回血管腫・血管奇形研究会, Jul. 2009, Japanese, 血管腫・血管奇形研究会, 札幌, Domestic conference四肢spindle cell hemangiomaの治療経験Oral presentation
- 第6回血管腫・血管奇形研究会, Jul. 2009, Japanese, 血管腫・血管奇形研究会, 札幌, Domestic conferenceKasabach-Merritt現象を呈した右手・前腕tufted angiomaの1例Oral presentation
- 第92回日本形成外科学会関西支部学術集会, Jun. 2009, Japanese, 日本形成外科学会, 大阪, Domestic conferenceリンパ管奇形に対する 当科でのエタノール硬化療法.Oral presentation
- 第25回日本皮膚悪性腫瘍学会学術大会, May 2009, Japanese, 日本皮膚悪性腫瘍学会, 岡山, Domestic conferenceGluteal fold V-Y advancement flapに基づき再建した外陰癌の1症例.Oral presentation
- 第52回日本形成外科学会総会・学術集会, Apr. 2009, Japanese, 日本形成外科学会総会, 横浜, Domestic conference-外鼻, 口唇を中心として-外鼻, 上口唇基底細胞癌の治療指針~再発ゼロ&マスクゼロを目指すPublic symposium
- 第52回日本形成外科学会総会・学術集会, Apr. 2009, Japanese, 日本形成外科学会, 横浜, Domestic conference全身麻酔下における皮膚レ-ザ-照射時の引火の危険性~多施設を対象としたアンケート調査に基づく検討~.Oral presentation
- 第52回日本形成外科学会総会・学術集会, Apr. 2009, Japanese, 日本形成外科学会, 横浜, Domestic conference静脈奇形の硬化療法における硬化剤の注入量と血色素尿の関連について-理想的な注入量を目指して-.Oral presentation
- 第52回日本形成外科学会総会・学術集会, Apr. 2009, Japanese, 日本形成外科学会, 横浜, Domestic conference手の静脈奇形に対する硬化療法.Oral presentation
- 第52回日本手の外科学会学術集会, Apr. 2009, Japanese, 日本手の外科学会, 東京, Domestic conference手に発生した静脈奇形に対する硬化療法 Sclerotherapy for venous malformations in the hand and forearm.Oral presentation
- 第1回日本創傷外科学会総会・学術集会, Jan. 2009, Japanese, 日本創傷外科学会, 東京, Domestic conference頭部皮膚潰瘍に対する手術方法の検討Oral presentation
- 第22回神戸形成外科集談会, Oct. 2008, Japanese, 神戸形成外科集談会, 神戸, Domestic conference遊離前腕皮弁による鼻部悪性腫瘍再建の経験Oral presentation
- 第17回日本形成外科学会基礎学術集会, Oct. 2008, Japanese, 日本形成外科学会, 東京, Domestic conference無血清での培養線維芽細胞の検討~安全な培養細胞注入を目指して~Public symposium
- 第26回日本頭蓋顎顔面外科学会学術集会, Oct. 2008, Japanese, 日本頭蓋顎顔面外科学会, 福岡, Domestic conference整復術後に眼球陥凹が遷延した外下方転移型頬骨骨折の2症例Oral presentation
- 第24回日本皮膚悪性腫瘍学会学術大会, Jul. 2008, Japanese, 日本皮膚悪性腫瘍学会, 岐阜, Domestic conference機能的耳介温存および根治的摘出を行った耳介後面有棘細胞癌の1症例Oral presentation
- 第90回日本形成外科学会関西支部学術集会, Jun. 2008, Japanese, 日本形成外科学会, 奈良, Domestic conference直腸瘻を伴った骨盤骨折後殿部難治性皮膚潰瘍の治療経験Oral presentation
- 第90回日本形成外科学会関西支部学術集会, Jun. 2008, Japanese, 日本形成外科学会, 奈良, Domestic conference足趾Garlic-Clove Fibromaの2症例Oral presentation
- 第5回血管腫・血管奇形研究会, Apr. 2008, Japanese, 血管腫・血管奇形研究会, 名古屋, Domestic conference全身麻酔下におけるDYE laser照射術中に引火による顔面熱傷を生じた一症例Oral presentation
- 第51回日本形成外科学会総会・学術集会, Apr. 2008, Japanese, 日本形成外科学会, 名古屋, Domestic conference静脈奇形に対する神戸大学の治療戦略Oral presentation
- 第51回日本形成外科学会総会・学術集会, Apr. 2008, Japanese, 日本形成外科学会, 名古屋, Domestic conference静脈奇形に対する硬化療法による治療経験-治療効果と組織壊死について-Oral presentation
- 第5回血管腫・血管奇形研究会, Apr. 2008, Japanese, 血管腫・血管奇形研究会, 名古屋, Domestic conferenceVenous Malformation のより確実な診断にむけて~病理所見と画像所見を比較した観点から~Oral presentation
- 第89回日本形成外科学会関西支部学術集会, Dec. 2007, Japanese, 日本形成外科学会, 高槻, Domestic conference逆行性皮弁により再建した前足部皮膚潰瘍の2例.Oral presentation
- 第89回日本形成外科学会関西支部学術集会, Dec. 2007, Japanese, 日本形成外科学会, 高槻, Domestic conferenceInfantile Hemangiomaの潰瘍形成に関する検討.Oral presentation
- 第25回日本頭蓋顎顔面外科学会学術集会, Nov. 2007, Japanese, 日本頭蓋顎顔面外科学会, 東京, Domestic conference内視鏡下経鼻腔的整復術(EER)は眼窩内側壁骨折治療の標準的術式となり得るか.Oral presentation
- 第25回日本頭蓋顎顔面外科学会学術集会, Nov. 2007, Japanese, 日本頭蓋顎顔面外科学会, 東京, Domestic conference上顎部分切除症例に対する遊離皮弁による再建手術の経験.Oral presentation
- 第25回日本頭蓋顎顔面外科学会学術集会, Nov. 2007, Japanese, 日本頭蓋顎顔面外科学会, 東京, Domestic conference硬膜外膿瘍に対し遊離広背筋皮弁とGORE-TEXを用いた1例.Oral presentation
- 第16回日本形成外科学会基礎学術集会, Oct. 2007, Japanese, 日本形成外科学会, 神戸, Domestic conference組織内脂肪酸組成解析によるscarless wound healingへのアプローチ.Public symposium
- 第34回日本マイクロサイジャリー学会学術集会, Oct. 2007, Japanese, 日本マイクロサイジャリー学会, 福島, Domestic conference喉頭全摘舌根部部分切除症例に対する舌動脈再建の治療経験.Oral presentation
- 第9回日本褥瘡学会学術集会, Sep. 2007, Japanese, 日本褥瘡学会, 前橋, Domestic conference坐骨結節切除により会陰部褥瘡を生じた車いす患者2例の報告.Oral presentation
- 第31回日本頭頸部癌学会・第28回頭頸部手術手技研究会, Jun. 2007, Japanese, 日本頭頸部癌学会, 横浜, Domestic conference頭頸部再建におけるconventional flap,とくに前腕皮弁のreliabilityとversatilityについて.Public symposium
- 第31回日本頭頸部癌学会, Jun. 2007, Japanese, 日本頭頸部癌学会, 横浜, Domestic conference頭頸部再建Conventional flap vs.Perforator flapとくに前腕皮弁のrealiabilityとversatilityOral presentation
- 第27回日本静脈学会総会, Jun. 2007, Japanese, 日本静脈学会, 京都, Domestic conference静脈奇形の治療戦略 血行動態を考慮した静脈奇形に対する我々の治療戦略 硬化療法の適応と限界について.Public symposium
- 第23回日本皮膚悪性腫瘍学会, May 2007, Japanese, 日本皮膚悪性腫瘍学会, 新潟, Domestic conference頭部への放射線療法により発生した基底細胞癌の2例.Oral presentation
- 第24回日本皮膚悪性腫瘍学会, May 2007, Japanese, 日本皮膚悪性腫瘍学会, 新潟, Domestic conference当科における肺癌皮膚転移切除症例の検討.Oral presentation
- 第50回日本形成外科学会総会・学術集会, Apr. 2007, Japanese, 日本形成外科学会, 東京, Domestic conference乳房温存手術後に生じた皮膚潰瘍症例の検討.Oral presentation
- 第50回日本形成外科学会総会・学術集会, Apr. 2007, Japanese, 日本形成外科学会, 東京, Domestic conference静脈奇形硬化療法における術中透視下病変造影の重要性.Oral presentation
- 第50回日本形成外科学会総会・学術集会, Apr. 2007, Japanese, 日本形成外科学会, 東京, Domestic conference口唇部血液貯留性病変に対する硬化療法による治療経験.Oral presentation
- 日本頭頸部癌学会
- JAPAN SOCIETY OF CRANIO-MAXILLO-FACIAL SURGERY
- 日本創傷外科学会
- JAPANESE SOCIETY OF PRESSURE ULCERS
- 日本皮膚悪性腫瘍学会
- JAPANESE SOCIETY FOR RECONSTRUCTIVE MICROSURGERY
- JAPAN SOCIETY FOR LASER SURGERY AND MEDICINE
- 日本血管腫血管奇形学会
- JAPAN SOCIETY OF PLASTIC AND RECONSTRUCTIVE SURGERY
- 日本学術振興会, 科学研究費助成事業, 基盤研究(C), 神戸大学, 01 Apr. 2024 - 31 Mar. 2027Gq変異による悪性腫瘍転移能への影響を探る-Melanomaをモデルとして-
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Kobe University, Apr. 2023 - Mar. 2026Is mechanical stimulation involved in worsening arteriovenous malformations?
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Kobe University, 01 Apr. 2021 - 31 Mar. 2025Transfection of plasmid vector for AMPs to wound treatmentわれわれは抗菌ペプチドであるdefensinに注目し、これを培養細胞において強制的に発現させることで細胞が感染への抵抗性を示すことを確認することを第一の目標とした。human defensinはアルファ型とベータ型とに分類され。さらにそのサブファミリーが存在する。これらはそれぞれに抗菌スペクトラムや発現部位が異なることが明らかとなっている。われわれはhuman beta defensin-3に注目した。本ペプチドは広い抗菌スペクトラムを持つためである。殺菌活性は細胞外に分泌して作用しなくてはならず、シグナルペプチドを組み合わせる必要があると考えられた。一方で、各defensinには一次構造にはシグナルペプチドが含まれており、この配列をベクターに組み込むこととして発現ベクターを設計した。この時、CMVプロモータ下流に位置させることとしたが、これとは別に発現が傾向タンパク質により確認できるように双方向性の発現ベクターを選択した。 まずカスタム合成によりhuman defense-3の全長配列を作成した。これに対してPCRを行うことで全長配列を増幅した。この配列をpBIおよびpBAプラスミドベクターに組み込みを行なっている。得られたクローンの塩基配列を現在確認している。 今後、プラスミドベクターへの組み込みが確認されたのち、ヒト培養皮膚線維芽細胞に導入し、ELISA法などにより培養上澄中に含まれるdefensinの発現量の測定や細菌耐性について検討を行う予定である。この細菌耐性の検討を行うにあたり、病原性を持つ細菌によるモデル化は汎用性に乏しいため、納豆菌によるバイオフィルム形成実験も併せて行なっている。
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Kobe University, 01 Apr. 2021 - 31 Mar. 2025Mechanism of hair cycle with irradiation of blue lightわれわれはヒト皮膚に光受容タンパク質が発現し、この発現はGPCRのセカンドメッセンジャーの1つであるGqを介して、細胞内シグナルへと変換されることを明らかにした。この過程でヒト皮膚の光受容タンパク質の1つであるMelanopsin (以下、OPN4)の発現動態を観察したところ、毛包や脂腺などの付属器にOPN4の強い発現と、Gqの共発現している所見を見出し、外毛根鞘および毛乳頭細胞におけるOPN4およびGnaqの強い発現を認めた。これは、青色光がOPN4を介して細胞内シグナルへと変換されることを示唆している。青色光の照射により、 細胞増殖シグナルであるERK1/2のリン酸化を促進すること、細胞レベルでの生体時計を調節することを見出していることから、青色光の①体内時計と毛周期の連動、②毛乳頭細胞への影響、③毛髪のメラニン保持の促進について検討することとした。 ① 毛髪から、実体顕微鏡下に毛乳頭部分を分離・培養し、毛乳頭細胞・毛母細胞の単離培養を行う。hBmal1およびhPer2遺伝子のプロモーター領域を組み込んだルシフェラーゼ発現ベクターを導入し、培養下にreal-time Luciferase assayを行い、青色光の照射により時計遺伝子の発現がリセットされることを確認した。 ② ①で得られた毛乳頭細胞を利用し、青色光を照射後、ウェスタンブロッティング法によりERK1/2のリン酸化の促進を確認する。次にend-point Luciferase assayを行い、SRF(ERK1/2の下流)の転写促進を確認する。さらにscratch assayおよびBRdU法により、細胞が青色光の照射により増殖することを確認する。③ 青色光によりMITFの転写促進を、real time PCRにより確認する。次に、reporter assayによりtyrosinaseの転写の促進を確認する。
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), 01 Apr. 2020 - 31 Mar. 2024Analysis of metastasis and growth of melanoma cells under irradiation of specific light exposure with Gq mutation虹彩に発生する悪性黒色腫(以下Melanoma)のうち、遠隔転移を起こした群ではGタンパク質ファミリーのうちGqαサブユニット群(以下Gq)の遺伝子変異が高率に認められること、また動物実験により、Gq遺伝子変異株ではMAPキナーゼ系の活性化(細胞増殖の活性化)および有意に転移をきたしたことが報告された。その後、Melanomaのみならず消化器系や呼吸器系に発生した悪性腫瘍においても同様の知見が報告されつつある。本研究の目的は、光とMelanomaの関連においてこれまで示されてきた「光線暴露が発生の危険因子である」ことに加え、「光線暴露は増殖・転移の危険因子でもある」ことを細胞生物学的に示すことにある。われわれは2つのMelanoma細胞株(MEWO株およびG361株)を研究対象として選んだ。これらの細胞株をモデルとし、Gq変異を加えることで、Melanomaの転移活性への影響を検討するため、まず、それぞれの細胞株におけるGq(GnaqおよびGq11)の遺伝子変異について探索を行なった。それぞれの細胞株から抽出したmRNAを元に、cDNAライブラリーを作成し、これに対して全長のGqに対するPCRを行なった。これをクローニングすることで、これらの遺伝子配列を解析した。その結果、いずれの細胞株においてもDNAレベルでは変異が認められるもののアミノ酸配列には影響を持たなかった。次に、変異を導入するためにゲノム編集を行うこととした。まずはGnaqをターゲットに、R183Q変異の導入を計画した。これに沿って、CRISPR/CAS9を用いたベクターの配列を設計した。同時にssODNの配列(1塩基置換)を設計した。これに沿って、Cas9と同時発現ベクターを構築した。
- 国立研究開発法人日本医療研究開発機構, 臨床研究・治験推進研究事業(委託事業), 杏林大学, Jan. 2021 - Mar. 2023, Coinvestigator静脈奇形に対するモノエタノールアミンオレイン酸塩を用いた硬化療法の有効性および安全性を評価する医師主導治験
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Kobe University, Apr. 2020 - Mar. 2023, Principal investigatorBiological analysis of smooth muscle cells in soft tissue vascular malformation脈管奇形は先天性の脈管形成異常である。特に動静脈奇形や静脈奇形では軟部組織の醜状変 形にとどまらず、筋・骨格系の変形、病変からの出血など組織破壊的となることもあり、日 常生活に著しい制限を生じる。病変の多くは進行性であり、難治病変では進行を止める手段 さえない場合がある。動静脈奇形や静脈奇形を含めた脈管奇形の病態生理および悪化の機序 にはなお不明な点が多い。われわれは本研究を通じて、脈管奇形のうち特に静脈奇形におけ る悪化機序について、主に「血管平滑筋細胞」に焦点を当てて分子生物学的側面より評価し、本疾患の分類・診断基準作成の補助ならびに疾患治療の確立へ結びつけることを目的とした。本年度は「血管平滑筋細胞」の細胞培養を行い、免疫組織学的検討ならびにMTTアッセイによる増殖能の確認を行い細胞培養法に関する手技の確立を行った。
- 学術研究助成基金助成金/基盤研究(C), Apr. 2018 - Mar. 2021Competitive research funding
- 科学研究費補助金/基盤研究(B), Apr. 2018 - Mar. 2021Competitive research funding
- 学術研究助成基金助成金/基盤研究(C), Mar. 2018 - Mar. 2021乳児血管腫におけるstem cellの関与 ~増殖・分化機構の解明~Competitive research funding
- 国立研究開発法人日本医療研究開発機構, 臨床研究・治験推進研究事業, 大阪医科薬科大学, Apr. 2019 - Mar. 2020静脈奇形に対するモノエタノールアミンオレイン酸塩を用いた硬化療法の有効性および安全性の検討
- 厚生労働科学研究費補助金難治性疾患等政策研究事業, Apr. 2017 - Mar. 2020難治性血管腫・血管奇形・リンパ管腫・リンパ管腫症および関連疾患についての調査研究班Competitive research funding
- 学術研究助成基金助成金/基盤研究(C), Apr. 2016 - Mar. 2019Competitive research funding
- 学術研究助成基金助成金/基盤研究(C), Apr. 2016 - Mar. 2019, Principal investigatorCompetitive research funding
- 学術研究助成基金助成金/挑戦的萌芽研究, Apr. 2013 - Mar. 2016Competitive research funding
- 学術研究助成基金助成金/基盤研究(C), Apr. 2013 - Mar. 2016, Principal investigatorCompetitive research funding
- Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Kobe University, 2011 - 2012, Principal investigatorWe analyzed the expression of 5 kinds of prostanoid receptors on lymphatic vessel, TP, IP, EP2, EP4, DP1, which are related to the contraction and extension of vasoactivity. All of these receptors were expressed on lymphatic vessel and patterns of expression were compatible to arteries. Our result suggest that prostanoid mayrelate to the activity of lymphatic vessels.Competitive research funding