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TAKAO Toshitatsu
Graduate School of Medicine / Department of Medical Device Engineering
Associate Professor

Researcher basic information

■ Research Areas
  • Life sciences / Tumor diagnostics and therapeutics

Research activity information

■ Paper
  • Hiroshi Saiga, Taro Oshikiri, Hironobu Goto, Yasufumi Koterazawa, Takashi Kato, Yukari Adachi, Toshitatsu Takao, Ryuichiro Sawada, Hitoshi Harada, Naoki Urakawa, Hiroshi Hasegawa, Shingo Kanaji, Kimihiro Yamashita, Takeru Matsuda, Yuzo Kodama, Yoshihiro Kakeji
    Elsevier BV, Dec. 2024, Journal of Gastrointestinal Surgery, 28(12) (12), 2001 - 2007
    Scientific journal

  • Hiroshi Takayama, Toshitatsu Takao, Douglas Motomura, Hitomi Hori, Yoshinori Morita, Takashi Toyonaga, Yuzo Kodama
    Dec. 2024, Endoscopy, 56(S 01) (S 01), E35-E36, English, International magazine
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • Hirofumi Abe, Tomoya Sako, Yoshinobu Yamamoto, Atsushi Ikeda, Fumiaki Kawara, Takayuki Ose, Toshitatsu Takao, Yasuaki Kitamura, Ryusuke Ariyoshi, Yoshinori Morita, Tsukasa Ishida, Takuya Ikegawa, Ryosuke Ishida, Tetsuya Yoshizaki, Hiroya Sakaguchi, Takashi Toyonaga, Yuzo Kodama
    Apr. 2024, BMJ Open
    [Refereed]
    Scientific journal

  • Tetsuya Yoshizaki, Yoshinobu Yamamoto, Tomoya Sako, Yasuaki Kitamura, Takayuki Ose, Tsukasa Ishida, Atsushi Ikeda, Ryusuke Ariyoshi, Mineo Iwatate, Fumiaki Kawara, Shinwa Tanaka, Toshitatsu Takao, Yoshinori Morita, Takashi Toyonaga, Yuzo Kodama
    BACKGROUND AND AIMS: Perforation during esophageal endoscopic submucosal dissection (ESD) typically results from electrical damage. However, there are cases in which perforation occurs due to segmental absence of intestinal musculature (SAIM) without iatrogenic muscular injury. We investigated the occurrence rate and clinical course of SAIM during esophageal ESD. METHODS: We conducted a retrospective review of esophageal ESDs performed between 2013 and 2019 in 10 centers in Japan. RESULTS: Five of 1708 patients (0.29%) received ESD for esophageal cancer and had SAIM. The median muscular defect size was 20 mm. All lesions were resected without discontinuation. After resection, three patients were closed with Endoloop. Four patients had mediastinal emphysema. All patients were managed conservatively. CONCLUSIONS: SAIM is a very rare condition, which is usually only diagnosed during ESD. Physicians performing esophageal ESD should be aware about SAIM. When SAIM is detected, the ESD technique should be modified to prevent full-thickness perforation.
    Nov. 2023, Gastrointestinal endoscopy, English, International magazine
    Scientific journal

  • Yoshinobu Yamamoto, Tetsuya Yoshizaki, Saeko Kushida, Shinwa Tanaka, Takayuki Ose, Tsukasa Ishida, Yasuaki Kitamura, Tomoya Sako, Mineo Iwatate, Atsushi Ikeda, Ryusuke Ariyoshi, Fumiaki Kawara, Hirofumi Abe, Toshitatsu Takao, Yoshinori Morita, Yasushi Sano, Eiji Umegaki, Hogara Nishisaki, Takashi Toyonaga, Yuzo Kodama
    OBJECTIVES: Endoscopic submucosal dissection (ESD) for superficial esophageal squamous cell carcinoma (ESCC) is performed for the treatment of lesions with varied backgrounds and factors. However, the predictive factors associated with the technical difficulty of ESD remain unknown in patients with varied lesions. Therefore, this study aimed to identify the predictive factors associated with the technical difficulty of ESD for ESCC using a retrospective cohort. METHODS: This multicenter, retrospective study was conducted in 10 hospitals in Japan. Consecutive patients who underwent esophageal ESD between January 2013 and December 2019 were enrolled. Lesions of subepithelial tumors, adenocarcinoma, and adenoma were excluded. Difficult lesions were defined as ESD requiring a long procedure time (≥120 min), perforation development, piecemeal resection, or discontinued ESD. In the present study, the clinical factors were assessed to identify the technical difficulty of ESD using univariate and multivariate analyses. RESULTS: Among 1708 lesions treated with esophageal ESD, eight subepithelial tumors, 44 adenocarcinomas, and two adenomas were excluded. Finally, 1505 patients with 1654 lesions were analyzed, and 217 patients with 217 lesions (13.1%) were classified as patients with difficult lesions. In multivariate analysis, the predictive factors associated with the technical difficulty of ESD were as follows: tumors with varices, tumors with diverticulum, antiplatelet use (discontinued), circumference of tumor (≥1/2), preoperative tumor size ≥30 mm, trainee, and nonhigh-volume center. CONCLUSION: This multicenter retrospective study identified the predictive factors associated with the technical difficulty of ESD for ESCC with varied backgrounds and factors.
    Aug. 2023, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, English, International magazine
    Scientific journal

  • Tatsuya Nakai, Tetsuya Yoshizaki, Shinwa Tanaka, Yoshinobu Yamamoto, Tomoya Sako, Yasuaki Kitamura, Takayuki Ose, Tsukasa Ishida, Atsushi Ikeda, Ryusuke Ariyoshi, Mineo Iwatate, Fumiaki Kawara, Toshitatsu Takao, Yoshinori Morita, Takashi Toyonaga, Yuzo Kodama
    BACKGROUND: Heavy drinking is associated with esophageal cancer and esophageal varices. However, there are limited reports of endoscopic resection for esophageal cancer with esophageal varices. In this multicenter study, we clarified the safety and efficacy of endoscopic submucosal dissection for superficial esophageal cancer with esophageal varices. METHODS: In this multicenter, retrospective, observational study, patients underwent esophageal endoscopic submucosal dissection at 10 referral centers in Japan from January 2013 to December 2019. We analyzed characteristics including backgrounds and varices, treatment outcomes, and adverse events in cases with esophageal varices. RESULTS: A total of 1708 patients were evaluated, 27 (1.6%) of whom had esophageal varices. In patients with esophageal varices, the en bloc resection rate and R0 resection rate were 100% and 77.8%, respectively. Patients with esophageal varices had longer procedure times than patients without esophageal varices (p = 0.015). There was no significant difference in adverse events. There was no significant difference in procedure time and number of adverse events between patients who underwent pretreatment and those who did not. There was no significant difference in these outcomes for patients with lesions on varices compared to those without. Child-Pugh classification and location of the lesions also did not affect these outcomes. CONCLUSIONS: Esophageal cancer with esophageal varices could be treated endoscopically safely and effectively.
    Jul. 2023, Esophagus : official journal of the Japan Esophageal Society, 20(3) (3), 515 - 523, English, Domestic magazine
    Scientific journal

  • Kazunori Tsuda, Shinwa Tanaka, Tetsuya Yoshizaki, Yoshinobu Yamamoto, Takayuki Ose, Tsukasa Ishida, Yasuaki Kitamura, Daisuke Obata, Mineo Iwatate, Atsushi Ikeda, Ryusuke Ariyoshi, Fumiaki Kawara, Hiroshi Takihara, Hirofumi Abe, Toshitatsu Takao, Yoshinori Morita, Yasushi Sano, Eiji Umegaki, Hogara Nishisaki, Takashi Toyonaga, Yuzo Kodama
    INTRODUCTION: Favorable long-term outcomes of endoscopic submucosal dissection (ESD) for early remnant gastric cancer (ERGC) have been reported in single-center studies from advanced institutions. However, no studies have examined the long-term outcomes using a multicenter database. This study aimed to investigate the long-term outcomes of the aforementioned approach using a large multicenter database. METHODS: This retrospective multicenter cohort study included 242 cases with 256 lesions that underwent ESD for ERGC between April 2009 and March 2019 across 12 centers. We investigated the long-term outcomes of these patients with the Kaplan-Meier method, and the relationship between curability, additional treatment, or hospital category, and the survival time was evaluated using the log-rank test. RESULTS: During the median follow-up period of 48.4 months, the 5-year overall survival rate was 81.3%, and the 5-year gastric cancer-specific survival rate was 98.1%. The survival time of patients of endoscopic curability (eCura) C-2 without additional surgery was significantly shorter than the corresponding of patients of eCura A/B/C-1 and eCura C-2 with additional surgery. There was no significant difference in either overall survival or gastric cancer-specific survival rate between the high-volume and non-high-volume hospitals. CONCLUSION: The gastric cancer-specific survival of ESD for ERGC using a multicenter database was favorable. ESD for ERGC is widely applicable regardless of the hospital case volume. Management in accordance with the latest guidelines will lead to long-term survival.
    Jun. 2023, Digestion, 1 - 10, English, International magazine
    Scientific journal

  • 当院での虫垂開口部の大腸病変に対するESDの治療戦略と成績
    津田 一範, 吉崎 哲也, 豊永 高史, 永木 瑞穂, 石田 亮介, 堀 瞳, 高山 弘志, 上田 千勢, 阪口 博哉, 阿部 洋文, 池澤 伸明, 鷹尾 まど佳, 鷹尾 俊達, 森田 圭紀, 児玉 裕三
    (一社)日本消化器内視鏡学会, Apr. 2023, Gastroenterological Endoscopy, 65(Suppl.1) (Suppl.1), 892 - 892, Japanese

  • Hikari Asahara, Toshitatsu Takao, Yumiko Asahara, Masakyo Asahara, Douglas Motomura, Hiroya Sakaguchi, Tetsuya Yoshizaki, Nobuaki Ikezawa, Madoka Takao, Yoshinori Morita, Takashi Toyonaga, Masato Komatsu, Ryoji Kushima, Yuzo Kodama
    Objective We explored the clinicopathological characteristics and disease frequency of oxyntic gland neoplasms (OGNs). Methods We retrospectively evaluated the data of patients pathologically diagnosed with OGN at an internal medicine clinic. Patients A total of 13,240 upper gastrointestinal endoscopies were performed on 7,488 patients between December 1, 2017, and March 31, 2021. Results We identified 27 patients with 30 histopathologically confirmed OGNs, yielding a disease frequency of 0.36% (27/7,488). Furthermore, multiple simultaneous lesions were found in 3 of 27 patients (11%). One (3.3%) of the 30 lesions was present in the antrum, whereas the remaining lesions occurred in the body of the stomach. Nine (33%) of the 27 patients had no history of Helicobacter pylori infection, whereas the remaining 18 (67%) were either currently or had been previously infected. Nevertheless, 27/30 lesions (90%) still occurred in non-atrophied regions. After endoscopic treatment, a histopathological examination of the resected specimens revealed submucosal infiltration in 8 (44%) of the 18 lesions; however, none of the lesions showed submucosal desmoplasia. For all patients with submucosal involvement, only observation was performed. There were no recurrent lesions found on follow-up. Conclusion The period prevalence of OGN was 0.36%, which is much higher than previously reported. The discovery of a small submucosal appearing lesion with a faded yellow or white color and dilated microvasculature, especially in a non-atrophic area of the stomach, should raise suspicion for an OGN, which can be endoscopically managed.
    Feb. 2023, Internal medicine (Tokyo, Japan), English, Domestic magazine
    Scientific journal

  • 胃・十二指腸ESDにおける高難度症例への対処 幽門輪に接する胃・十二指腸腫瘍に対するESD治療成績と術後合併症の検討
    高山 弘志, 豊永 高史, 池澤 伸明, 吉崎 哲也, 阿部 洋文, 阪口 博哉, 鷹尾 俊達, 森田 圭紀, 児玉 裕三
    (一社)日本胃癌学会, Feb. 2023, 日本胃癌学会総会記事, 95回, 228 - 228, Japanese

  • Hiroshi Takayama, Takashi Toyonaga, Tetsuya Yoshizaki, Hirofumi Abe, Tatsuya Nakai, Chise Ueda, Satoshi Urakami, Hidetoshi Kaku, Yusaku Shimamoto, Kei Matsumoto, Kazunori Tsuda, Hiroya Sakaguchi, Shinichi Baba, Hiroshi Takihara, Nobuaki Ikezawa, Shinwa Tanaka, Madoka Takao, Toshitatsu Takao, Yoshinori Morita, Yuzo Kodama
    INTRODUCTION: Gastric stasis due to deformation occurs after endoscopic submucosal dissection in the lower part of the stomach. Endoscopic balloon dilation can improve gastric stasis due to stenosis; however, endoscopic balloon dilation cannot improve gastric stasis due to deformation. Furthermore, the characteristics of gastric stasis due to deformation are unknown. This study aimed to evaluate the characteristics of gastric stasis due to deformation after endoscopic submucosal dissection in the lower part of the stomach, focusing on the differences between stenosis and deformation. METHODS: We retrospectively reviewed 41 patients with gastric stasis after endoscopic submucosal dissection in the lower part of the stomach. We evaluated the characteristics of cases with gastric stasis due to deformation, such as the risk factors of deformation and the rate of deformation in each group with risk factors. RESULTS: Deformation was observed in 12% (5/41) of the patients with gastric stasis. All cases of deformation had a circumferential extent of the mucosal defect greater than 3/4. The number of cases with pyloric dissection was significantly lower in the deformation group than in the non-deformation group (0% vs. 72%; p = 0.004). The deformation group also had a significantly higher number of cases with angular dissection than the non-deformation group (100% vs. 17%; p < 0.001). Moreover, the deformation cases had a significantly larger specimen diameter (p < 0.001). Deformation was observed only in cases with angular and non-pyloric dissections. Deformation was not observed in cases with angular and pyloric dissections. CONCLUSIONS: All cases of gastric stasis due to deformation had a circumferential extent of the mucosal defect greater than 3/4. Deformation was also likely to occur in cases with a larger dissection that exceeded the angular region without pyloric dissection.
    2023, Digestion, 104(4) (4), 320 - 327, English, International magazine
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • 森田 圭紀, 鷹尾 俊達, 金治 新悟
    (一社)日本消化器内視鏡学会, Dec. 2022, Gastroenterological Endoscopy, 64(12) (12), 2524 - 2532, Japanese

  • 経時的に形態変化を観察し得た表在性非乳頭部十二指腸上皮性腫瘍の一例
    永木 瑞穂, 池澤 伸明, 堀 瞳, 石田 亮介, 高山 弘志, 津田 一範, 阪口 博哉, 阿部 洋文, 吉崎 哲也, 鷹尾 まど佳, 鷹尾 俊達, 森田 圭紀, 豊永 高史, 児玉 裕三
    日本消化器内視鏡学会-近畿支部, Nov. 2022, 日本消化器内視鏡学会近畿支部例会プログラム・抄録集, 109回, 103 - 103, Japanese

  • Shingo Kanaji, Yoshinori Morita, Takuya Kudo, Kouta Yamada, Takashi Kato, Arata Sakai, Toshitatsu Takao, Ryuichiro Sawada, Hitoshi Harada, Naoki Urakawa, Hironobu Goto, Hiroshi Hasegawa, Kimihiro Yamashita, Takeru Matsuda, Taro Oshikiri, Takashi Toyonaga, Yuzo Kodama, Yoshihiro Kakeji
    PURPOSE: No study has focused on the safety and feasibility of our previously developed open-window suturing technique to close mucosal defects on the pancreatic side after endoscopic submucosal dissection from the opened duodenal wall. This study aimed to evaluate the safety and usefulness of laparoscopic endoscopic cooperative surgery for duodenal tumors for treating superficial non-ampullary duodenal epithelial tumors on the pancreatic side of the duodenum. METHODS: This retrospective study included 61 consecutive patients who underwent surgery during August 2014-November 2021. After dissection when the tumor was on the pancreatic side, we sutured the mucosal defect from the opened duodenal wall. A preoperative endoscopic pancreatic stent was placed for tumors within 1 cm of the ampulla of Vater. The surgical outcomes were compared between tumors on the pancreatic and non-pancreatic sides. RESULTS: There were 27 and 34 patients with tumors on the pancreatic and non-pancreatic sides, respectively. The patient characteristics were similar. Preoperative pancreatic stents were placed in four patients in the pancreatic side group. The median operative time was significantly longer on the pancreatic side than in the non-pancreatic side group (241 vs. 209 min, P = 0.02). In one patient in the pancreatic side group, an intraoperative injury of the ampulla of Vater was successfully treated with intraoperative management. There were no significant differences in the incidence of postoperative grade II or higher complications between the groups. CONCLUSIONS: Laparoscopic endoscopic cooperative surgery for duodenal tumors for treating superficial non-ampullary duodenal epithelial tumors on the pancreatic side is safe and feasible.
    Jul. 2022, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 26(11) (11), 2266 - 2273, English, International magazine
    Scientific journal

  • Hiroshi Takayama, Toshitatsu Takao, Ryo Masumura, Yoshikazu Yamaguchi, Ryo Yonezawa, Hiroya Sakaguchi, Yoshinori Morita, Takashi Toyonaga, Kazutaka Izumiyama, Yuzo Kodama
    Objective Endoscopic reports are conventionally written at the end of each procedure, and the endoscopist must complete the report from memory. To make endoscopic reporting more efficient, we developed a new speech recognition (SR) system that generates highly accurate endoscopic reports based on structured data entry. We conducted a pilot study to examine the performance of this SR system in an actual endoscopy setting with various types of background noise. Methods In this prospective observational pilot study, participants who underwent upper endoscopy with our SR system were included. The primary outcome was the correct recognition rate of the system. We compared the findings generated by the SR system with the findings in the handwritten report prepared by the endoscopist. The initial correct recognition rate, number of revisions, finding registration time, and endoscopy time were also analyzed. Results Upper endoscopy was performed in 34 patients, generating 128 findings of 22 disease names. The correct recognition rate was 100%, and the median number of revisions was 0. The median finding registration time was 2.57 (interquartile range [IQR], 2.33-2.92) seconds, and the median endoscopy time was 234 (IQR, 194-227) seconds. Conclusion The SR system demonstrated high recognition accuracy in the clinical setting. The finding registration time was extremely short.
    Jun. 2022, Internal medicine (Tokyo, Japan), English, Domestic magazine
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • Nobuaki Ikezawa, Takashi Toyonaga, Shinwa Tanaka, Tetsuya Yoshizaki, Toshitatsu Takao, Hirofumi Abe, Hiroya Sakaguchi, Kazunori Tsuda, Satoshi Urakami, Tatsuya Nakai, Taku Harada, Kou Miura, Takahisa Yamasaki, Stuart Kostalas, Yoshinori Morita, Yuzo Kodama
    BACKGROUND/AIMS: Endoscopic submucosal dissection (ESD) for diverticulum-associated colorectal lesions is generally contraindicated because of the high risk of perforation. Several studies on patients with such lesions treated with ESD have been reported recently. However, the feasibility and safety of ESD for lesions in proximity to a colonic diverticulum (D-ESD) have not been fully clarified. The aim of this study was to evaluate the feasibility and safety of D-ESD. METHODS: D-ESD was defined as ESD for lesions within approximately 3 mm of a diverticulum. Twenty-six consecutive patients who underwent D-ESD were included. Two strategic approaches were used depending on whether submucosal dissection of the diverticulum-related part was required (strategy B) or not (strategy A). Treatment outcomes and adverse events associated with each strategy were analyzed. RESULTS: The en bloc resection rate was 96.2%. The rates of R0 and curative resection in strategies A and B were 80.8%, 73.1%, 84.6%, and 70.6%, respectively. Two cases of intraoperative perforation and one case of delayed perforation occurred. The delayed perforation case required emergency surgery, but the other cases were managed conservatively. CONCLUSION: D-ESD may be a feasible treatment option. However, it should be performed in a high-volume center by expert hands because it requires highly skilled endoscopic techniques.
    May 2022, Clinical endoscopy, 55(3) (3), 417 - 425, English, International magazine
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • Yoshitaka Takegawa, Toshitatsu Takao, Hiroya Sakaguchi, Tatsuya Nakai, Kazuhiro Takeo, Yoshinori Morita, Takashi Toyonaga, Yuzo Kodama
    Combined use of fibrin glue and polyglycolic acid (PGA) sheets has attracted attention as a preventive measure for complications associated with endoscopic submucosal dissection. However, fibrin glue is a protein that may be dissolved by gastric acid. We evaluated the effect of artificial gastric acid on fibrin clot. The dissolution time of three layers of fibrin glue with PGA sheets was measured in five groups (pH 1.2, 2.0, 4.0, 5.5, and 6.0 with pepsin). Measurements of three samples per group were made. The mean number of the remaining layers at each measurement point was observed for 168 h. The time to complete dissolution of the three layers of fibrin gel in the three samples was 2.5 h at pH 1.2, 5 h at pH 2.0, 24 h at pH 4.0, and 48 h and 6 h at pH 5.5. In order to maintain fibrin glue in the stomach for a long period, there was a need to avoid pepsin activation secondary to acidification of gastric juice. The use of strong antacids is recommended.
    Apr. 2022, Scientific reports, 12(1) (1), 6986 - 6986, English, International magazine
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • ESD traineeからExpertを目指して
    池澤 伸明, 森田 圭紀, 中井 達也, 津田 一範, 賀来 英俊, 松本 慶, 阪口 博哉, 阿部 洋文, 吉崎 哲也, 田中 心和, 鷹尾 まど佳, 鷹尾 俊達, 豊永 高史, 児玉 裕三
    (一社)日本胃癌学会, Mar. 2022, 日本胃癌学会総会記事, 94回, 515 - 515, Japanese

  • ESD traineeからExpertを目指して
    池澤 伸明, 森田 圭紀, 中井 達也, 津田 一範, 賀来 英俊, 松本 慶, 阪口 博哉, 阿部 洋文, 吉崎 哲也, 田中 心和, 鷹尾 まど佳, 鷹尾 俊達, 豊永 高史, 児玉 裕三
    (一社)日本胃癌学会, Mar. 2022, 日本胃癌学会総会記事, 94回, 515 - 515, Japanese

  • 貧血症状を契機に発見されESDにて切除し得た巨大十二指腸Brunner腺過形成の一例
    賀来 英俊, 吉崎 哲也, 中井 達也, 高山 弘志, 津田 一範, 松本 慶, 池澤 伸明, 阪口 博哉, 阿部 洋文, 鷹尾 まど佳, 鷹尾 俊達, 森田 圭紀, 豊永 高史, 児玉 貴之, 横崎 宏, 伊藤 智雄, 児玉 裕三
    日本消化器病学会-近畿支部, Feb. 2022, 日本消化器病学会近畿支部例会プログラム・抄録集, 116回, 124 - 124, Japanese

  • 胃腫瘍内視鏡治療における工夫 幽門側胃切除後の残胃吻合部の早期胃癌に対する内視鏡的粘膜下層剥離術の再建術式に基づく治療困難性および有効性、安全性の検討
    松本 慶, 鷹尾 俊達, 田中 心和, 森田 圭紀, 豊永 高史, 児玉 裕三
    (一社)日本消化管学会, Jan. 2022, 日本消化管学会雑誌, 6(Suppl.) (Suppl.), 168 - 168, Japanese

  • 胃腫瘍内視鏡治療における工夫 幽門側胃切除後の残胃吻合部の早期胃癌に対する内視鏡的粘膜下層剥離術の再建術式に基づく治療困難性および有効性、安全性の検討
    松本 慶, 鷹尾 俊達, 田中 心和, 森田 圭紀, 豊永 高史, 児玉 裕三
    (一社)日本消化管学会, Jan. 2022, 日本消化管学会雑誌, 6(Suppl.) (Suppl.), 168 - 168, Japanese

  • 低分化型腺癌と鑑別を要した乳癌胃転移の一例
    井上 築, 吉崎 哲也, 中井 達也, 高山 弘志, 津田 一範, 松本 慶, 賀来 英俊, 阪口 博哉, 阿部 洋文, 池澤 伸明, 鷹尾 まど佳, 鷹尾 俊達, 森田 圭紀, 豊永 高史, 児玉 裕三
    日本消化器内視鏡学会-近畿支部, Dec. 2021, 日本消化器内視鏡学会近畿支部例会プログラム・抄録集, 107回, 113 - 113, Japanese

  • Barrett食道腺癌ESD後の異時性多発病変に対し残存Barrett粘膜を含めESDで完全切除した一例
    津田 一範, 豊永 高史, 高山 弘志, 阿部 洋文, 中井 達也, 嶋本 有策, 賀来 英俊, 松本 慶, 池澤 伸明, 阪口 博哉, 吉崎 哲也, 鷹尾 まど佳, 鷹尾 俊達, 森田 圭紀, 児玉 裕三
    日本消化器内視鏡学会-近畿支部, Dec. 2021, 日本消化器内視鏡学会近畿支部例会プログラム・抄録集, 107回, 120 - 120, Japanese

  • 胃前庭部の粘膜下層剥離術後通過障害に対するバルーン拡張術無効例の検討
    高山 弘志, 豊永 高史, 吉崎 哲也, 中井 達也, 賀来 英俊, 松本 慶, 津田 一範, 阪口 博哉, 阿部 洋文, 池澤 伸明, 鷹尾 まど佳, 鷹尾 俊達, 森田 圭紀, 児玉 裕三
    日本消化器内視鏡学会-近畿支部, Dec. 2021, 日本消化器内視鏡学会近畿支部例会プログラム・抄録集, 107回, 121 - 121, Japanese

  • Hiroshi Takayama, Takashi Toyonaga, Tetsuya Yoshizaki, Hirofumi Abe, Tatsuya Nakai, Chise Ueda, Satoshi Urakami, Hidetoshi Kaku, Yusaku Shimamoto, Kei Matsumoto, Kazunori Tsuda, Hiroya Sakaguchi, Koki Matsuoka, Shinichi Baba, Hiroshi Takihara, Nobuaki Ikezawa, Shinwa Tanaka, Madoka Takao, Toshitatsu Takao, Yoshinori Morita, Yuzo Kodama
    BACKGROUND AND AIM: There have been studies on risk factors for stenosis after pyloric endoscopic submucosal dissection (ESD). However, the most appropriate strategies for the management of cases with these risk factors have not been established. This study aimed to investigate post-ESD management by evaluating the timing of stenosis and the effectiveness of endoscopic balloon dilation (EBD) after pyloric ESD. METHODS: We retrospectively reviewed cases of pyloric ESD. We first reassessed risk factors for stenosis in multivariate analysis and receiver operating characteristic curve and defined patients with the identified risk factors as the risk group. The primary outcome was the timing of stenosis in the risk group assessed by the Kaplan-Meier method. RESULTS: We reviewed 159 cases with pyloric ESD and observed pyloric stenosis in 25 cases. Cases with circumferential mucosal defect ≥ 76% were identified as the risk group. The stenosis-free probability in the risk group was 97% (95% confidence interval [CI]: 79-100%), 94% (95% CI: 76-98%), and 85% (95% CI: 66-93%) on days 7, 14, and 21, respectively. It decreased every week thereafter and did not significantly change after day 56. Twenty-three stenosis cases, except for conservative improvement, including six whole circumferential pyloric ESD cases, were improved by EBD without complications. CONCLUSIONS: Post-ESD stenosis often developed from the third to the eighth week. In all pyloric ESD cases, including whole circumferential pyloric ESD cases, pyloric stenosis was improved following EBD without complications.
    Wiley, Nov. 2021, Journal of Gastroenterology and Hepatology, 36(11) (11), 3158 - 3163, English, International magazine
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • 金治 新悟, 裏川 直樹, 鷹尾 俊達, 森田 圭紀, 豊永 高史, 掛地 吉弘
    金原出版(株), Oct. 2021, 手術, 75(11) (11), 1673 - 1677, Japanese

  • 表在性非乳頭部十二指腸上皮性腫瘍に対する腹腔鏡内視鏡合同手術の当院の成績
    鷹尾 俊達, 森田 圭紀, 児玉 裕三
    (一社)日本消化器内視鏡学会, Oct. 2021, Gastroenterological Endoscopy, 63(Suppl.2) (Suppl.2), 1860 - 1860, Japanese

  • 早期胃癌で発見された胎児消化管上皮類似癌の3例
    山中 大樹, 池澤 伸明, 中井 達也, 高山 弘志, 上田 千勢, 津田 一範, 松本 慶, 賀来 英俊, 阪口 博哉, 阿部 洋文, 吉崎 哲也, 鷹尾 まど佳, 鷹尾 俊達, 森田 圭紀, 豊永 高史, 児玉 裕三
    日本消化器病学会-近畿支部, Sep. 2021, 日本消化器病学会近畿支部例会プログラム・抄録集, 115回, 68 - 68, Japanese

  • Kei Matsumoto, Shinwa Tanaka, Takashi Toyonaga, Nobuaki Ikezawa, Mari Nishio, Masanao Uraoka, Tomoatsu Yoshihara, Hiroya Sakaguchi, Hirofumi Abe, Tetsuya Yoshizaki, Madoka Takao, Toshitatsu Takao, Yoshinori Morita, Hiroshi Yokozaki, Yuzo Kodama
    Background/Aims: The anastomotic site after distal gastrectomy is the area most affected by duodenogastric reflux. Different reconstruction methods may affect the lesion characteristics and treatment outcomes of remnant gastric cancers at the anastomotic site. We retrospectively investigated the clinicopathologic and endoscopic submucosal dissection outcomes of remnant gastric cancers at the anastomotic site.Methods: We recruited 34 consecutive patients who underwent endoscopic submucosal dissection for remnant gastric cancer at the anastomotic site after distal gastrectomy. Clinicopathology and treatment outcomes were compared between the Billroth II and non-Billroth II groups.Results: The tumor size in the Billroth II group was significantly larger than that in the non-Billroth II group (22 vs. 19 mm; p=0.048). More severe gastritis was detected endoscopically in the Billroth II group (2 vs. 1.33; p=0.0075). Moreover, operation time was longer (238 vs. 121 min; p=0.004) and the frequency of bleeding episodes was higher (7.5 vs. 3.1; p=0.014) in the Billroth II group.Conclusions: Compared to remnant gastric cancers in non-Billroth II patients, those in the Billroth II group had larger lesions with a background of severe remnant gastritis. Endoscopic submucosal dissection for remnant gastric cancers in Billroth II patients involved longer operative times and more frequent bleeding episodes than that in patients without Billroth II.
    The Korean Society of Gastrointestinal Endoscopy, Aug. 2021, Clinical Endoscopy, 55(1) (1), 86 - 94
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • 正中弓状靱帯症候群に合併した後下膵十二指腸動脈瘤破裂に対するコイル塞栓後に十二指腸狭窄をきたした一例
    中辻 政志, 池澤 伸明, 鷹尾 俊達, 中井 達也, 賀来 英俊, 森田 圭紀, 豊永 高史, 児玉 裕三
    日本消化器内視鏡学会-近畿支部, Jul. 2021, 日本消化器内視鏡学会近畿支部例会プログラム・抄録集, 106回, 96 - 96, Japanese

  • 豊永 高史, 阪口 博哉, 池澤 伸明, 中野 佳子, 田中 心和, 石田 司, 阿部 洋文, 吉崎 哲也, 鷹尾 俊達, 森田 圭紀, 馬場 慎一, 滝原 浩守, 西野 栄世, 横崎 宏, 児玉 裕三
    (株)医学書院, Jul. 2021, 胃と腸, 56(8) (8), 1047 - 1056, Japanese

  • Shinwa Tanaka, Tetsuya Yoshizaki, Yoshinobu Yamamoto, Takayuki Ose, Tsukasa Ishida, Yasuaki Kitamura, Daisuke Obata, Mineo Iwatate, Mikio Fujita, Atsushi Ikeda, Ryusuke Ariyoshi, Fumiaki Kawara, Hirofumi Abe, Toshitatsu Takao, Yoshinori Morita, Yasushi Sano, Eiji Umegaki, Hogara Nishisaki, Takashi Toyonaga, Yuzo Kodama
    BACKGROUND: Endoscopic submucosal dissection (ESD) for remnant gastric cancer (RGC) after distal gastrectomy (DG) is considered technically challenging due to the narrow working space, and severe fibrosis and staples from the previous surgery. Technical difficulties of ESD for RGC after DG have not been thoroughly investigated. This study aimed to develop and validate a risk-scoring system for assessing the technical difficulty of ESD for RGC after DG in a large multicenter cohort. METHODS: We investigated patients who underwent ESD for RGC after DG in 10 institutions between April 2008 and March 2018. A difficult case was defined as ESD lasting ≥ 120 min, involving piecemeal resection, or the occurrence of perforation during the procedure. A risk-scoring system for the technical difficulty of the procedure was developed based on multiple logistic regression analyses, and its performance was internally validated using bootstrapping. RESULTS: A total of 197 consecutive patients with 201 lesions were analyzed. There were 90 and 111 difficult and non-difficult cases, respectively. The scoring model consisted of four independent risk factors and points of risk scores were assigned for each as follows: tumor size > 20 mm: 2 points; anastomosis site: 2 points; suture line: 1 point; and non-expert endoscopist: 2 points. The C-statistics of the scoring system for technical difficulty was 0.72. CONCLUSIONS: We developed a validated risk-scoring model for predicting the technical difficulty of ESD for RGC after DG that can contribute to its safer and more reliable performance.
    Springer Science and Business Media LLC, Apr. 2021, Surgical Endoscopy, 36(2) (2), 1482 - 1489, English, International magazine
    Scientific journal

  • 十二指腸表在型腫瘍に対する内視鏡診療(LECS vs EMR vs ESD vs経過観察) 表在型非乳頭部十二指腸上皮性腫瘍に対する腹腔鏡内視鏡合同手術の治療成績
    鷹尾 俊達, 森田 圭紀, 児玉 裕三
    (一社)日本消化器内視鏡学会, Apr. 2021, Gastroenterological Endoscopy, 63(Suppl.1) (Suppl.1), 848 - 848, Japanese

  • 進行食道癌に対する食道ステント留置後の食事摂取状況に関する検討
    賀来 英俊, 鷹尾 俊達, 中井 達也, 高山 弘志, 嶋本 有策, 上田 千勢, 津田 一範, 松本 慶, 池澤 伸明, 阪口 博哉, 松岡 晃生, 阿部 洋文, 吉崎 哲也, 鷹尾 まど佳, 森田 圭紀, 豊永 高史, 児玉 裕三
    (一社)日本消化器内視鏡学会, Apr. 2021, Gastroenterological Endoscopy, 63(Suppl.1) (Suppl.1), 910 - 910, Japanese

  • 幽門側胃切除後の残胃吻合部の早期胃癌に対する内視鏡的粘膜下層剥離術の再建術式に基づく治療困難性および有効性、安全性の検討
    松本 慶, 鷹尾 俊達, 田中 心和, 森田 圭紀, 豊永 高史, 児玉 裕三
    (一社)日本消化器内視鏡学会, Apr. 2021, Gastroenterological Endoscopy, 63(Suppl.1) (Suppl.1), 956 - 956, Japanese

  • Shingo Kanaji, Yoshinori Morita, Yuta Yamazaki, Yasunori Otowa, Toshitatsu Takao, Shinwa Tanaka, Naoki Urakawa, Masashi Yamamoto, Takeru Matsuda, Taro Oshikiri, Tetsu Nakamura, Satoshi Suzuki, Takashi Toyonaga, Yuzo Kodama, Yoshihiro Kakeji
    Wiley, Mar. 2021, Digestive Endoscopy, 33(3) (3), 373 - 380
    Scientific journal

  • Madoka Takao, Yoshitaka Takegawa, Toshitatsu Takao, Hiroya Sakaguchi, Yoshiko Nakano, Shinwa Tanaka, Yoshinori Morita, Takashi Toyonaga, Eiji Umegaki, Hiromu Kutsumi, Yuzo Kodama
    Abstract Background and study aims Adequate mucosal elevation by submucosal injection is crucial for patient safety and efficiency during endoscopic submucosal dissection (ESD). This study aimed to evaluate the efficacy of fibrin glue (FG) as a long-lasting submucosal injection agent and to evaluate the technical feasibility of FG injection for ESD. Materials and methods To compare the capabilities of different agents in maintaining submucosal evaluation, we injected FG, hyaluronic acid solution, and normal saline into the porcine gastric specimen that was incised into approximately 5 × 5 cm squares. Then, we measured the height of submucosal elevations over time. Moreover, three hypothetical lesions from the resected porcine stomach underwent ESD with FG injection. Thereafter, we conducted macroscopic and histopathologic analyses. Results FG maintained the greatest submucosal elevation among all the injection agents. Three ESD procedures were performed with en bloc resection. Both macroscopic and histopathologic findings showed a thick FG clot on the ulcers. Conclusions The FG solution can be potentially used as an ESD submucosal injection agent in an in vitro model.
    Georg Thieme Verlag KG, Mar. 2021, Endoscopy International Open, 09(03) (03), E319 - E323
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • Tomoya Sako, Takashi Toyonaga, Yoshiko Nakano, Shinwa Tanaka, Toshitatsu Takao, Shinichi Baba, Hiroshi Takihara, Yoshinori Morita, Eiji Umegaki, Yuzo Kodama
    BACKGROUND: Although postoperative strictures after endoscopic submucosal dissection (ESD) in the rectum are relatively rare, some rectal lesions require resection involving the anal canal, which is a narrow tract comprising squamous epithelium. To the best of our knowledge, no studies have investigated narrow anal canals when evaluating post-ESD strictures. This study aimed to evaluate the impact of resections involving the anal canal on postoperative stricture development. METHODS: Between April 2005 and October 2017, 707 rectal lesions were treated with ESD. We retrospectively investigated 102 lesions that required ≥ 75% circumferential resection. Risk factors for post-ESD stricture and, among patients with strictures, obstructive symptoms, and number of dilation therapies required were investigated. RESULTS: Post-ESD stricture occurred in 18 of 102 patients (17.6%). In the multivariate analysis, circumferential resection ≥ 90% and ESD involving the anal canal (ESD-IAC) were risk factors for postoperative strictures (P ≤ 0.0001 and 0.0115, respectively). Among the patients with strictures, obstructive symptoms were significantly related to anal strictures compared to rectal strictures (100% vs. 27.2%, P = 0.0041). Furthermore, the number of dilation therapies required was significantly greater among patients with anal strictures compared to those with rectal strictures (6.5 times vs. 2.7 times, P = 0.0263). CONCLUSION: Not only circumferential resection ≥ 90% but also ESD-IAC was a significant risk factor for the stricture after rectal ESD. Furthermore, anal strictures were associated with a significantly higher frequency of obstructive symptoms and larger number of required dilation therapies than were rectal strictures.
    Springer Science and Business Media LLC, Mar. 2021, Surgical endoscopy, 35(3) (3), 1307 - 1316, English, International magazine
    Scientific journal

  • Hiroya Sakaguchi, Toshitatsu Takao, Yoshitaka Takegawa, Yuki Koga, Kazunori Yamanaka, Masataka Sagata, Shinwa Tanaka, Yoshinori Morita, Takashi Toyonaga, Yuzo Kodama
    The Korean Society of Gastrointestinal Endoscopy, Jan. 2021, Clinical Endoscopy, 54(1) (1), 64 - 72
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • Helicobacter pylori未感染胃に生じたラズベリー様腺窩上皮型胃癌の1例
    堀谷 晋, 松岡 晃生, 鷹尾 俊達, 田中 心和, 阿部 洋文, 森田 圭紀, 豊永 高史, 児玉 裕三
    日本消化器内視鏡学会-近畿支部, Dec. 2020, 日本消化器内視鏡学会近畿支部例会プログラム・抄録集, 105回, 60 - 60, Japanese

  • PGAシートにて胃ESD後遅発性穿孔を閉鎖し得た一例
    山本 顕, 賀来 英俊, 鷹尾 俊達, 中井 達也, 高山 弘志, 嶋本 有策, 上田 千勢, 津田 一範, 松本 慶, 池澤 伸明, 阪口 博哉, 松岡 晃生, 阿部 洋文, 吉崎 哲也, 鷹尾 まど佳, 森田 圭紀, 豊永 高史, 児玉 裕三
    日本消化器内視鏡学会-近畿支部, Dec. 2020, 日本消化器内視鏡学会近畿支部例会プログラム・抄録集, 105回, 60 - 60, Japanese

  • Yoshiko Nakano, Toshitatsu Takao, Yoshinori Morita, Shinwa Tanaka, Takashi Toyonaga, Eiji Umegaki, Yuzo Kodama
    The Korean Society of Gastrointestinal Endoscopy, Sep. 2020, Clinical Endoscopy, 53(5) (5), 575 - 582
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • Nobuaki Ikezawa, Shinwa Tanaka, Hidetoshi Kaku, Toshitatsu Takao, Yoshinori Morita, Takashi Toyonaga, Masato Komatsu, Hiroshi Yokozaki, Tomoo Ito, Yuzo Kodama
    Springer Science and Business Media LLC, Aug. 2020, Clinical Journal of Gastroenterology, 13(4) (4), 512 - 516
    Scientific journal

  • Shinwa Tanaka, Takashi Toyonaga, Fumiaki Kawara, Daisuke Watanabe, Namiko Hoshi, Hirohumi Abe, Ryusuke Ariyoshi, Yoshiko Ohara, Toshitatsu Takao, Yoshinori Morita, Eiji Umegaki, Yuzo Kodama
    BACKGROUND AND AIM: One of the main concerns related to peroral endoscopic myotomy (POEM) is postoperative gastroesophageal reflux (GER). The two penetrating vessels (TPVs) that are found at the boundary between the circular and oblique muscles in the posterior cardia wall have been suggested to be a good indicator of the optimal distal extent of POEM. However, the effect of performing myotomy using the TPVs as an anatomical reference on the frequency of post-POEM GER has not been studied. METHODS: This study involved consecutive patients who underwent POEM for the treatment of achalasia between April 2015 and June 2017. All enrolled patients underwent POEM in the 5 o'clock position and were divided into two groups: the conventional line group (CL group, n = 31), in which the TPVs were not exposed during submucosal tunnel dissection in the cardia, and the TPVs line group (TPVs group, n = 83), in which the TPVs were exposed and gastric myotomy was performed along the right side of the TPVs to preserve the oblique muscle. Examinations for post-POEM GER were conducted 3 months after the POEM. RESULTS: The frequency of grade B or higher reflex esophagitis was 26/83 (31.3%) in the TPVs group and 18/31 (58.1%) in the CL group (P = 0.017). Nine of 83 patients (10.8%) had GER symptoms in the TPVs group, and six of 31 (19.4%) had GER symptoms in the CL group (P = 0.23). CONCLUSIONS: The novel myotomy method preserving oblique muscle using TPVs as anatomical landmarks significantly reduced the frequency of post-POEM GER.
    Wiley, Dec. 2019, Journal of gastroenterology and hepatology, 34(12) (12), 2158 - 2163, English, International magazine
    Scientific journal

  • Yoshiko Nakano, Toshitatsu Takao, Yoshinori Morita, Hiroya Sakaguchi, Shinwa Tanaka, Tsukasa Ishida, Takashi Toyonaga, Eiji Umegaki, Yuzo Kodama
    Springer Science and Business Media LLC, Jun. 2019, Surgical Endoscopy, 33(6) (6), 1795 - 1801
    Scientific journal

  • Hiroya Sakaguchi, Takashi Toyonaga, Hidetoshi Kaku, Yoshiko Nakano, Shinwa Tanaka, Toshitatsu Takao, Yuzo Kodama
    Georg Thieme Verlag KG, Apr. 2019, Endoscopy, 51(04) (04), E88 - E89, English, International magazine
    Scientific journal

  • Shinwa Tanaka, Takashi Toyonaga, Hidetoshi Kaku, Hiroya Sakaguchi, Shinichi Baba, Toshitatsu Takao, Yuzo Kodama
    Georg Thieme Verlag KG, Apr. 2019, Endoscopy, 51(04) (04), E90 - E91, English, International magazine
    Scientific journal

  • Daisuke Watanabe, Shinwa Tanaka, Fumiaki Kawara, Hirohumi Abe, Ryusuke Ariyoshi, Yoshiko Nakano, Toshitatsu Takao, Yoshinori Morita, Takashi Toyonaga, Eiji Umegaki, Yuzo Kodama
    Abstract Background and study aims Previously, we reported that esophageal muscle layer thickness was associated with technical complexity of peroral endoscopic myotomy (POEM). However, there are no data regarding the mid-term effects of POEM procedures on esophageal muscle layer thickness. Therefore, we conducted this study to elucidate mid-term effects of POEM procedures, and to examine whether postoperative changes in esophageal muscle layer thickness were related to particular clinico-pathological features in patients with esophageal motility disorders. Patients and methods Seventy-four consecutive patients with esophageal motility disorders who underwent POEM at Kobe University Hospital from April 2015 to December 2016 were prospectively recruited into this study. First, we investigated the esophageal muscle layer thickness values obtained at 1 year after POEM. Second, we evaluated the effects of a reduction in muscle layer thickness on various clinico-pathological features. Results At 1 year after POEM, mean thickness of the inner circular muscle at 0 cm, 5 cm, and 10 cm from the esophagogastric junction was 1.06 ± 0.45 mm, 0.99 ± 0.36 mm, and 0.97 ± 0.44 mm, respectively. Among all sites, muscle layer thickness had significantly decreased after POEM. However, univariate logistic regression analysis demonstrated that no clinical factors were associated with esophageal muscle layer thickness after POEM procedure. Conclusions We demonstrated for the first time that thickness of the esophageal muscle layer was significantly decreased after POEM. This result reveals that changes in esophageal muscle layer thickness caused by esophageal motility disorders are reversible.
    Georg Thieme Verlag KG, Apr. 2019, Endoscopy International Open, 07(04) (04), E525 - E532
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • Umaporn Seehawong, Yoshinori Morita, Yoshiko Nakano, Takehiro Iwasaki, Chonlada Krutsri, Hiroya Sakaguchi, Tomoya Sako, Toshitatsu Takao, Shinwa Tanaka, Takashi Toyonaga, Eiji Umegaki, Yuzo Kodama
    Springer Science and Business Media LLC, Feb. 2019, Clinical Journal of Gastroenterology, 12(1) (1), 29 - 33
    Scientific journal

  • Shinwa Tanaka, Takashi Toyonaga, Fumiaki Kawara, Daisuke Watanabe, Namiko Hoshi, Hirohumi Abe, Ryusuke Ariyoshi, Yoshiko Ohara, Tsukasa Ishida, Toshitatsu Takao, Yoshinori Morita, Eiji Umegaki
    Springer Science and Business Media LLC, Oct. 2018, Clinical Journal of Gastroenterology, 11(5) (5), 377 - 381
    Scientific journal

  • Elif Bilgic, Madoka Takao, Pepa Kaneva, Satoshi Endo, Toshitatsu Takao, Yusuke Watanabe, Katherine M. McKendy, Liane S. Feldman, Melina C. Vassiliou
    Background. Needs assessment identified a gap regarding laparoscopic suturing skills targeted in simulation. This study collected validity evidence for an advanced laparoscopic suturing task using an Endo StitchTM device. Methods. Experienced (ES) and novice surgeons (NS) performed continuous suturing after watching an instructional video. Scores were based on time and accuracy, and Global Operative Assessment of Laparoscopic Surgery. Data are shown as medians [25th-75th percentiles] (ES vs NS). Interrater reliability was calculated using intraclass correlation coefficients (confidence interval). Results. Seventeen participants were enrolled. Experienced surgeons had significantly greater task (980 [964-999] vs 666 [391-711], P = .0035) and Global Operative Assessment of Laparoscopic Surgery scores (25 [24-25] vs 14 [12-17], P = .0029). Interrater reliability for time and accuracy were 1.0 and 0.9 (0.74-0.96), respectively. All experienced surgeons agreed that the task was relevant to practice. Conclusion. This study provides validity evidence for the task as a measure of laparoscopic suturing skill using an automated suturing device. It could help trainees acquire the skills they need to better prepare for clinical learning.
    SAGE Publications, Jun. 2018, Surgical Innovation, 25(3) (3), 286 - 290, English, International magazine
    Scientific journal

  • Toshitatsu Takao, Ryo Masumura, Sumitaka Sakauchi, Yoshiko Ohara, Elif Bilgic, Eiji Umegaki, Hiromu Kutsumi, Takeshi Azuma
    Abstract Background and study aims We developed a new reporting system based on structured data entry, which selectively extracts only endoscopic findings from endoscopists’ oral statements and automatically inputs them into appropriate columns in real time during endoscopic procedures. Methods We compared the time for endoscopic procedures and report preparation (ER time) by using an esophagogastroduodenoscopy simulator in three groups: one preparing reports using a mouse after endoscopic procedures (CE group); a second group preparing reports by using voice alone during endoscopic procedures (SR group); and the final group preparing reports by operating the system with a foot switch and inputting findings using voice during endoscopic procedures (SR + FS group). For the SR and SR + FS groups, we identified the recognition rates of the speech recognition system. Results Mean ER times for cases with three findings each were 162, 130 and 119 seconds in the CE, SR and SR + FS groups, respectively. The mean ER times for cases with six findings each were 220, 144 and 128 seconds, respectively. The times in the SR and SR + FS groups were significantly shorter than that in the CE group (P < 0.017). The recognition rate of the SR group for cases with three findings each was 98.4 %, and 97.6 % in the same group for cases with six findings each. The rates in the SR + FS group were 95.2 % and 98.4 %, respectively. Conclusion Our reporting system was demonstrated to allow an endoscopist to efficiently complete the report in real time during endoscopic procedures.
    Georg Thieme Verlag KG, Jun. 2018, Endoscopy International Open, 06(06) (06), E676 - E687
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • Toshitatsu Takao, Yoshitaka Takegawa, Hiroyuki Ono, Madoka Takao, Shiro Oka, Noriko Shinya, Hiromu Kutsumi, Takeshi Azuma
    Background and aims Shielding methods for post-endoscopic submucosal dissection (ESD) ulcers have delivery-related problems. We developed an enveloped device for this purpose and evaluated its usefulness. Materials and methods Polyglycolic acid (PGA) sheets were delivered to six 3.0-cm ulcers in two resected porcine stomachs and six 5.0-cm ulcers in another three stomachs. In the regular method group, small PGA sheets were delivered via forceps. In the novel method group, a large PGA sheet was delivered via the new device. The methods were compared in terms of time, and macroscopic and histological findings of the ulcer floor. Results The median time required to cover a 3.0-cm ulcer was 0.39 min/cm2 in the novel method group and 1.03 min/cm2 in the regular method group (P = 0.03), and to cover a 5.0-cm ulcer was 0.38 min/cm2 and 0.85 min/cm2, respectively (P = 0.03). In the novel method group, the PGA sheets were in close contact, fully covering the ulcer floor. In the regular method group, the sheets were partly elevated from the ulcer floor. Conclusions This novel technique seems promising in this preliminary study.
    Georg Thieme Verlag KG, Jan. 2017, Endoscopy, 49(04) (04), 359 - 364, English, International magazine
    Scientific journal

  • Toshitatsu Takao, Yoshitaka Takegawa, Noriko Shinya, Kimihiro Tsudomi, Shiro Oka, Hiroyuki Ono
    Georg Thieme Verlag KG, Feb. 2015, Endoscopy International Open, 03(02) (02), E146 - E151
    Scientific journal

  • Fundamental examination into the use of fibrin glue and polyglycolic acid sheets as a method for covering post - ESD ulcers
    Yoshitaka Takegawa, Toshitatsu Takao, Hiroyuki Ono
    Japan Gastroenterological Endoscopy Society, 2015, Gastroenterological Endoscopy, 57(4) (4), 1150 - 1157, Japanese
    Scientific journal

  • Tomoko Hagiwara, Naomi Kakushima, Kenichiro Imai, Masaki Tanaka, Toshitatsu Takao, Kinichi Hotta, Yuichiro Yamaguchi, Kohei Takizawa, Hiroyuki Matsubayashi, Hiroyuki Ono, Takuma Oishi, Takashi Nakajima
    Springer Science and Business Media LLC, Apr. 2014, Clinical Journal of Gastroenterology, 7(2) (2), 123 - 128
    Scientific journal

  • Naomi Kakushima, Hiroyuki Ono, Toshitatsu Takao, Hideyuki Kanemoto, Keiko Sasaki
    Wiley, Apr. 2014, Digestive Endoscopy, 26, 35 - 40
    Scientific journal

  • Noboru Kawata, Naomi Kakushima, Masaki Tanaka, Hiroaki Sawai, Kenichiro Imai, Tomoko Hagiwara, Toshitatsu Takao, Kinichi Hotta, Yuichiro Yamaguchi, Kohei Takizawa, Hiroyuki Matsubayashi, Hiroyuki Ono
    Wiley, Mar. 2014, Digestive Endoscopy, 26(2) (2), 208 - 213
    Scientific journal

  • Naomi Kakushima, Tomoko Hagiwara, Masaki Tanaka, Hiroaki Sawai, Noboru Kawata, Kohei Takizawa, Kenichiro Imai, Toshitatsu Takao, Kinichi Hotta, Yuichiro Yamaguchi, Hiroyuki Matsubayashi, Hiroyuki Ono
    Wiley, Dec. 2013, United European Gastroenterology Journal, 1(6) (6), 453 - 460
    Scientific journal

  • Naomi Kakushima, Masaki Tanaka, Hiroaki Sawai, Kenichiro Imai, Noboru Kawata, Tomoko Hagiwara, Toshitatsu Takao, Kinichi Hotta, Yuichiro Yamaguchi, Kohei Takizawa, Hiroyuki Matsubayashi, Hiroyuki Ono
    Wiley, Jun. 2013, United European Gastroenterology Journal, 1(3) (3), 184 - 190
    Scientific journal

  • KINICHI HOTTA, YUICHIRO YAMAGUCHI, YUTAKA SAITO, TOSHITATSU TAKAO, HIROYUKI ONO
    Wiley, May 2012, Digestive Endoscopy, 24, 110 - 116
    Scientific journal

  • Hiroyuki Matsubayashi, Hiroaki Sawai, Hirokazu Kimura, Yuichiro Yamaguchi, Masaki Tanaka, Naomi Kakushima, Kohei Takizawa, Maho Kadooka, Toshitatsu Takao, Sachin Hebbar, Hiroyuki Ono
    Elsevier BV, Sep. 2011, Digestive and Liver Disease, 43(9) (9), 731 - 735
    Scientific journal

  • Hiroyuki Matsubayashi, Shohei Ooka, Hirokazu Kimura, Toshitatsu Takao, Yuichiro Yamaguchi, Hiroyuki Ono
    Hong Kong STM Publishing Co., Ltd., Apr. 2011, Journal of Interventional Gastroenterology, 1(2) (2), 90 - 92
    Scientific journal

  • Andres Sanchez-Yague, Yuichiro Yamaguchi, Toshitatsu Takao, Masaki Tanaka, Naomi Kakushima, Kohei Takizawa, Hisatomo Ikehara, Hiroyuki Matsubayashi, Hiroyuki Ono
    Elsevier BV, Feb. 2011, Gastrointestinal Endoscopy, 73(2) (2), 405 - 407
    Scientific journal

  • Toshitatsu Takao, Takeshi Ishikawa, Takashi Ando, Madoka Takao, Tsuguhiro Matsumoto, Yutaka Isozaki, Mika Okita, Yasuyuki Nagao, Hirokazu Oyamada, Keiichi Yokoyama, Atsushi Tatebe, Kazuhiko Uchiyama, Osamu Handa, Tomohisa Takagi, Nobuaki Yagi, Satoshi Kokura, Yuji Naito, Toshikazu Yoshikawa
    Aim. Chronic gastritis was assessed serologically, endoscopically and histologically to identify correlations between these methods.Methods. Subjects comprised 319 patients who had provided informed consent. Serological assessment of chronic gastritis was based on the pepsinogen test method. Endoscopic gastritis and histological gastritis were assessed and scored according to the Kimura-Takemoto classification system and the updated Sydney classification system respectively, and correlations between these three methods were studied.Results. Pepsinogen I/II ratio showed a significant correlation to the extent of mononuclear cell infiltration of the gastric corpus. When histological gastritis was divided, on the basis of the distribution of mononuclear cell infiltration, into gastritis limited to the antrum and corpus gastritis, these types were distinguished with high accuracy using a pepsinogen I/II ratio of 3 as the cutoff. A good correlation was also seen between pepsinogen I/II ratio and development of atrophy in endoscopic gastritis, where groups with and without advanced atrophy were also distinguished with high accuracy using a cutoff value of 3.Conclusion. Significant correlations exist between serum pepsinogen levels, endoscopic gastritis, and histological gastritis. Pepsinogen I/II ratio allows prediction of the existence of endoscopic gastritis and histological gastritis, or the extent of their development, with high accuracy.
    Hindawi Limited, 2011, Gastroenterology Research and Practice, 2011, 1 - 7, English, International magazine
    Scientific journal

  • Successful treatment for advanced hepatocellular carcinoma by hepatic arterial infusion of CDDP powder as second-line chemotherapy
    Yasuyuki Gen, Hiroyuki Kimura, Reiko Akitake, Aya Sakai, Akifumi Fukui, Toshitatsu Takao, Satoshi Ikezawa, Atsuhiro Masuda, Hidetaka Takashima, Eiji Funatsu, Hideki Nakamura, Yusuke Okuyama, Masahiro Arai, Nobuaki Yagi, Hiromu Kutsumi, Sotaro Fujimoto, Yoshito Takeuchi
    2006, Gan to kagaku ryoho. Cancer & chemotherapy, 33(4) (4), 505 - 508, Japanese
    Scientific journal

  • 高齢者の総胆管結石症例に対するダブルチューブステントの有用性
    八木 信明, 鷹尾 俊達, 新井 正弘, 久津見 弘, 藤本 荘太郎, 古倉 聡, 内藤 裕二, 吉田 憲正, 吉川 敏一
    (一社)日本抗加齢医学会, Jun. 2005, 日本抗加齢医学会総会プログラム・抄録集, 5回, 71 - 71, Japanese
    [Refereed]

  • 高齢者における出血性消化性潰瘍の救急初療の現状
    鷹尾 俊達, 八木 信明, 新井 正弘, 久津見 弘, 藤本 荘太郎, 古倉 聡, 内藤 裕二, 吉田 憲正, 吉川 敏一
    (一社)日本抗加齢医学会, Jun. 2005, 日本抗加齢医学会総会プログラム・抄録集, 5回, 71 - 71, Japanese
    [Refereed]

  • Toshitatsu Takao, Yutaka Kobayashi, Junya Kuroda, Atsusi Omoto, Tomoko Nishimura, Yuri Kamitsuji, Etsuko Fukiya, Chie Nakamura, Shinya Kimura, Toshikazu Yoshikawa
    Wiley, Dec. 2004, American Journal of Hematology, 77(4) (4), 419 - 420, English, International magazine
    Scientific journal

■ MISC
  • 十二指腸表在型腫瘍に対する内視鏡診療(LECS vs EMR vs ESD vs経過観察) 表在型非乳頭部十二指腸上皮性腫瘍に対する腹腔鏡内視鏡合同手術の治療成績
    鷹尾 俊達, 森田 圭紀, 児玉 裕三
    (一社)日本消化器内視鏡学会, Apr. 2021, Gastroenterological Endoscopy, 63(Suppl.1) (Suppl.1), 848 - 848, Japanese

  • 進行食道癌に対する食道ステント留置後の食事摂取状況に関する検討
    賀来 英俊, 鷹尾 俊達, 中井 達也, 高山 弘志, 嶋本 有策, 上田 千勢, 津田 一範, 松本 慶, 池澤 伸明, 阪口 博哉, 松岡 晃生, 阿部 洋文, 吉崎 哲也, 鷹尾 まど佳, 森田 圭紀, 豊永 高史, 児玉 裕三
    (一社)日本消化器内視鏡学会, Apr. 2021, Gastroenterological Endoscopy, 63(Suppl.1) (Suppl.1), 910 - 910, Japanese

  • 幽門側胃切除後の残胃吻合部の早期胃癌に対する内視鏡的粘膜下層剥離術の再建術式に基づく治療困難性および有効性、安全性の検討
    松本 慶, 鷹尾 俊達, 田中 心和, 森田 圭紀, 豊永 高史, 児玉 裕三
    (一社)日本消化器内視鏡学会, Apr. 2021, Gastroenterological Endoscopy, 63(Suppl.1) (Suppl.1), 956 - 956, Japanese

  • 小腸多発血管異形成に対するダブルバルーン内視鏡、およびアルゴンプラズマ凝固術後に、遅発性小腸穿孔を来たした一例
    吉治 誠, 松本 慶, 鷹尾 俊達, 岡本 典大, 宮崎 はる香, 松岡 晃生, 竹中 春香, 大井 充, 森田 圭紀, 豊永 高史, 児玉 裕三
    日本消化器病学会-近畿支部, Feb. 2021, 日本消化器病学会近畿支部例会プログラム・抄録集, 114回, 72 - 72, Japanese

  • Diagnostic imaging and endoscopic treatment of colon cancer
    津田一範, 鷹尾俊達, 児玉裕三
    (株)へるす出版, 2021, 消化器外科, 44(6) (6), 730 - 737, Japanese

  • Helicobacter pylori未感染胃に生じたラズベリー様腺窩上皮型胃癌の1例
    堀谷 晋, 松岡 晃生, 鷹尾 俊達, 田中 心和, 阿部 洋文, 森田 圭紀, 豊永 高史, 児玉 裕三
    日本消化器内視鏡学会-近畿支部, Dec. 2020, 日本消化器内視鏡学会近畿支部例会プログラム・抄録集, 105回, 60 - 60, Japanese

  • PGAシートにて胃ESD後遅発性穿孔を閉鎖し得た一例
    山本 顕, 賀来 英俊, 鷹尾 俊達, 中井 達也, 高山 弘志, 嶋本 有策, 上田 千勢, 津田 一範, 松本 慶, 池澤 伸明, 阪口 博哉, 松岡 晃生, 阿部 洋文, 吉崎 哲也, 鷹尾 まど佳, 森田 圭紀, 豊永 高史, 児玉 裕三
    日本消化器内視鏡学会-近畿支部, Dec. 2020, 日本消化器内視鏡学会近畿支部例会プログラム・抄録集, 105回, 60 - 60, Japanese

  • 軟性持針器を用いた内視鏡的胃全層縫合術の開発
    阪口 博哉, 鷹尾 俊達, 森田 圭紀
    (一社)日本消化器内視鏡学会, Aug. 2020, Gastroenterological Endoscopy, 62(Suppl.1) (Suppl.1), 1390 - 1390, Japanese

  • 表在性非乳頭部十二指腸上皮性腫瘍に対する治療戦略 表在型非乳頭部十二指腸上皮性腫瘍に対する腹腔鏡内視鏡合同手術の治療成績(膵臓側病変を含む)
    鷹尾 俊達, 森田 圭紀, 児玉 裕三
    (一社)日本消化器内視鏡学会, Aug. 2020, Gastroenterological Endoscopy, 62(Suppl.1) (Suppl.1), 1169 - 1169, Japanese

  • ガイドライン追補版導入後の抗血栓薬服用者における胃ESDの後出血に関する検討
    津田 一範, 田中 心和, 池澤 伸明, 阿部 洋文, 鷹尾 俊達, 森田 圭紀, 豊永 高史, 児玉 裕三
    (一社)日本消化器内視鏡学会, Aug. 2020, Gastroenterological Endoscopy, 62(Suppl.1) (Suppl.1), 1322 - 1322, Japanese

  • 当院における産学・医工連携による消化器内視鏡分野への取り組み
    森田 圭紀, 鷹尾 俊達, 児玉 裕三, 阪口 博哉
    (一社)日本消化器内視鏡学会, Aug. 2020, Gastroenterological Endoscopy, 62(Suppl.1) (Suppl.1), 1359 - 1359, Japanese

  • NSAIDs外用薬によって多発小腸潰瘍をきたした1例
    城端慧, 津田一範, 田中心話, 乾沙苗, 宮崎はる香, 徳永英里, 賀来英俊, 阿部洋文, 具潤亜, 迫智也, 池澤伸明, 若原ちか, 大井充, 鷹尾まど佳, 鷹尾俊達, 飛松和俊, 森田圭紀, 豊永高史, 児玉裕三
    日本消化器病学会-近畿支部, 2020, 日本消化器病学会近畿支部例会プログラム・抄録集, 112th, 110 - 110, Japanese

  • 大腸ESDの工夫 3 トラクション(4)エンドトラック法
    阪口博哉, 豊永高史, 豊永高史, 田中心和, 鷹尾俊達, 森田圭紀, 児玉裕三
    (株)日本メディカルセンター, 2020, 臨床消化器内科, 35(3) (3), 269 - 274, Japanese

  • 肛門管切開を伴う内視鏡的粘膜下層剥離術(ESD)の術後狭窄の検討
    迫 智也, 豊永 高史, 中野 佳子, 田中 心和, 鷹尾 俊達, 森田 圭紀, 児玉 裕三
    (一社)日本消化管学会, Jan. 2020, 日本消化管学会雑誌, 4(Suppl.) (Suppl.), 265 - 265, Japanese

  • 短期間で増大傾向を示した十二指腸低分化腺癌/印環細胞癌の一例
    土井 真由実, 迫 智也, 鷹尾 俊達, 池澤 伸明, 田中 心和, 森田 圭紀, 豊永 高史, 児玉 裕三
    日本消化器病学会-近畿支部, Oct. 2019, 日本消化器病学会近畿支部例会プログラム・抄録集, 111回, 74 - 74, Japanese

  • バルーン拡張術が有効であったPlummer-vinson症候群の一例
    津田 一範, 田中 心和, 阿部 洋文, 若原 ちか, 浦上 聡, 朝治 直紀, 松本 慶, 池澤 伸明, 賀来 英俊, 阪口 博哉, 迫 智也, 鷹尾 まど佳, 鷹尾 俊達, 森田 圭紀, 豊永 高史, 児玉 裕三
    日本消化器病学会-近畿支部, Oct. 2019, 日本消化器病学会近畿支部例会プログラム・抄録集, 111回, 109 - 109, Japanese

  • 当院での粘膜切開生検法45例の検討 組織採取不成功例の検討を中心に
    鷹尾 俊達, 中野 佳子, 森田 圭紀
    (一社)日本消化器内視鏡学会, May 2019, Gastroenterological Endoscopy, 61(Suppl.1) (Suppl.1), 928 - 928, Japanese

  • Transanal Endoscopic Microsurgery(TEM)後の遺残再発病変に対するESDの有用性と安全性についての検討
    池澤 伸明, 田中 心和, 石田 司, 中野 佳子, 鷹尾 俊達, 森田 圭紀, 梅垣 英次, 豊永 高史, 児玉 裕三
    (一社)日本消化器内視鏡学会, May 2019, Gastroenterological Endoscopy, 61(Suppl.1) (Suppl.1), 940 - 940, Japanese

  • 肛門管切開を伴う内視鏡的粘膜下層剥離術(ESD)の術後狭窄の検討
    迫 智也, 中野 佳子, 豊永 高史, 田中 心和, 鷹尾 俊達, 森田 圭紀, 梅垣 英次, 児玉 裕三
    (一社)日本消化器内視鏡学会, May 2019, Gastroenterological Endoscopy, 61(Suppl.1) (Suppl.1), 946 - 946, Japanese

  • 当院で胃ESD後にPGAシートを貼付した16症例の検討
    阪口 博哉, 鷹尾 俊達, 森田 圭紀, 児玉 裕三
    (一社)日本消化器内視鏡学会, May 2019, Gastroenterological Endoscopy, 61(Suppl.1) (Suppl.1), 1019 - 1019, Japanese

  • エキスパートへの道-上部消化管 胃 病変内に線維化を伴うESDのコツ
    豊永高史, 石田司, 鷹尾俊達, 児玉裕三
    (株)東京医学社, 2019, 消化器内視鏡, 31(1) (1), 80 - 84, Japanese

  • Endoscopic submucosal dissection in a patient with idiopathic mesenteric phlebosclerosis
    R. Schroder, Yoshiko Nakano, T. Toyonaga, H. Abe, R. Ariyoshi, S. Tanaka, T. Takao, Y. Morita, E. Umegaki, Y. Kodama
    2019, Acta Gastro-Enterologica Belgica, 82(2) (2), 341 - 342
    Report scientific journal

  • 軟性持針器を用いた内視鏡的胃全層縫合術の開発
    阪口 博哉, 鷹尾 俊達, 森田 圭紀
    (一社)日本消化器内視鏡学会, Oct. 2018, Gastroenterological Endoscopy, 60(Suppl.2) (Suppl.2), 2141 - 2141, Japanese

  • 阪口博哉, 豊永高史, 中野佳子, 有吉隆佑, 阿部洋文, 田中心和, 鷹尾俊達, Morita Yoshinori, 梅垣英次
    (株)東京医学社, Jul. 2018, 消化器内視鏡, 30(7) (7), 859 - 867, Japanese
    Introduction scientific journal

  • Double scope法による軟性持針器を用いた内視鏡的胃全層縫合術の開発
    阪口 博哉, 鷹尾 俊達, 森田 圭紀
    (一社)日本消化器内視鏡学会, Apr. 2018, Gastroenterological Endoscopy, 60(Suppl.1) (Suppl.1), 691 - 691, Japanese

  • フィブリン糊とポリグリコール酸シートを用いた被覆法における反重力面へのシート貼付に関する基礎的検討
    竹川 佳孝, 鷹尾 俊達, 小原 佳子, 阪口 博哉, 森田 圭紀
    (一社)日本消化器内視鏡学会, Apr. 2018, Gastroenterological Endoscopy, 60(Suppl.1) (Suppl.1), 869 - 869, Japanese

  • ポリグリコール酸シート運搬・貼付時のエンベロープ型デリバリーシステムの有用性に関する検討
    鷹尾 俊達, 竹川 佳孝, 小原 佳子, 阪口 博哉, 森田 圭紀
    (一社)日本消化器内視鏡学会, Apr. 2018, Gastroenterological Endoscopy, 60(Suppl.1) (Suppl.1), 870 - 870, Japanese

  • Effectiveness of self-expandable metal stent for afferent loop obstruction caused by cancer recurrence after pancreaticoduodenectomy
    Arata Sakai, Hideyuki Shiomi, Seiji Fujigaki, Koudai Yamanaka, Takeshi Ezaki, Yuichi Hirata, Takao Iemoto, Takashi Nakagawa, Yousuke Yagi, Takashi Kobayashi, Toshitatsu Takao, Mamoru Takenaka, Yoshifumi Arisaka, Hiromu Kutsumi, Yoshihiro Okabe, Takeshi Azuma
    Nov. 2014, JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 29, 43 - 43, English
    Summary international conference

  • ブラシ後膵管洗浄とENPD留置による細胞診が確定診断に有用であった膵上皮内癌の1症例
    木村 公一, 松林 宏行, 鷹尾 まど佳, 鷹尾 俊達, 田中 雅樹, 角嶋 直美, 滝沢 耕平, 堀田 欣一, 山口 裕一郎, 小野 裕之
    肝胆膵治療研究会, Aug. 2012, 肝胆膵治療研究会誌, 10(1) (1), 122 - 122, Japanese

  • 血清IgG4値による自己免疫性膵炎の臨床的差異
    松林 宏行, 木村 公一, 山口 裕一郎, 滝沢 耕平, 角嶋 直美, 田中 雅樹, 西出 憲史, 鷹尾 俊達, 鷹尾 まど佳, 柳下 淳, 澤井 寛明, 今井 健一郎, 黄 勇澤, 川田 登, 大岡 正平, 萩原 朋子, 小野 裕之
    肝胆膵治療研究会, Aug. 2011, 肝胆膵治療研究会誌, 9(1) (1), 122 - 122, Japanese

  • 胃腫瘍に対する内視鏡的粘膜下層剥離術(ESD法)の有用性と今後の展望について
    八木 信明, 秋武 玲子, 坂井 文, 福居 顕文, 玄 泰行, 鷹尾 俊達, 池澤 聡, 増田 充弘, 高島 英隆, 船津 英司, 中村 英樹, 奥山 祐右, 木村 浩之, 新井 正弘, 藤本 荘太郎
    (一社)日本消化器内視鏡学会, Apr. 2006, Gastroenterological Endoscopy, 48(Suppl.1) (Suppl.1), 751 - 751, Japanese

  • Second-Line治療としての粉末Cisplatin製剤肝動注が効果的であった肝細胞癌の1例
    玄 泰行, 木村 浩之, 秋武 玲子, 坂井 文, 福居 顕文, 鷹尾 俊達, 池澤 聡, 増田 充弘, 高島 英隆, 船津 英司, 中村 英樹, 奥山 祐右, 新井 正弘, 八木 信明, 久津見 弘, 藤本 荘太郎, 竹内 義人
    (株)癌と化学療法社, Apr. 2006, 癌と化学療法, 33(4) (4), 505 - 508, Japanese

  • 急性膵炎11例の検討
    玄 泰行, 久津見 弘, 鷹尾 俊達, 池澤 聡, 西田 憲生, 葺屋 悦子, 増田 充弘, 船津 英司, 中村 英樹, 奥山 祐右, 木村 浩之, 八木 信明, 藤本 荘太郎
    (一財)日本消化器病学会, Mar. 2005, 日本消化器病学会雑誌, 102(臨増総会) (臨増総会), A350 - A350, Japanese

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