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官澤 洋平
医学部附属病院 総合内科
助教

研究者基本情報

■ 学位
  • 学士（医学）, 東北大学
■ 研究キーワード
  • 多疾患併存
  • 誤嚥性肺炎
  • 総合診療
  • 心不全
  • 病院総合診療医
■ 研究分野
  • ライフサイエンス / 内科学一般 / 多疾患併存
  • ライフサイエンス / 内科学一般 / 病院総合医
■ 委員歴
  • 2026年07月 - 現在, 米国内科学会日本支部, Public Relations Committee（PRC）アドバイザー
  • 2026年02月 - 現在, 日本病院総合診療医学会, 評議員
  • 2026年01月 - 現在, 一般社団法人日本専門医機構, 総合診療専門医認定試験委員会 CBT 試験委員
  • 2024年08月 - 現在, 一般社団法人日本専門医機構, 総合診療専門医検討委員会 生涯学修部会／プログラム部会／専門医指導医部会 部会員部会員
  • 2023年06月 - 現在, 日本内科学会, 専門医部会 多疾患併存マネジメント ワーキンググループ
  • 2019年09月 - 現在, 日本プライマリ・ケア連合学会, ダイバシティ推進委員会
  • 2025年12月 - 2026年06月, 米国内科学会日本支部, Member, Annual Meeting Organizing Committee (AMOC)
  • 2022年09月 - 2026年06月, 米国内科学会日本支部, Public Relations Committee（PRC）委員長
  • 2025年07月 - 2026年03月, 厚生労働省「医療の効率化に向けた領域別タスクシフト推進事業」における プライマリ・ケア領域における特定行為研修修了看護師活用ガイド作成ワー キンググループ, ワーキンググループメンバー, https://jmsb.app.box.com/s/dzvxtkab7pk7n4aa4vmv5c0465ranq9m
  • 2023年10月 - 2026年02月, 日本病院総合診療医学会, 若手部会執行部 副代表
  • 2025年06月 - 2025年12月, 臨床研修協議会, 第7回 卒後医師臨床研修プログラム責任者講習会 タスクフォース
  • 2025年11月 - 2025年11月, 日本プライマリ・ケア連合学会近畿ブロック支部 第38回近畿地方会 実行委員, キャリアCafé担当委員
  • 2022年08月 - 2024年08月, 一般社団法人日本専門医機構, 第5期 総合診療専門医検討委員会 生涯学修部会 部会員
  • 2021年10月 - 2023年09月, 日本病院総合診療医学会, 若手部会執行部
  • 2021年09月 - 2022年08月, 米国内科学会日本支部, Public Relations Committee（PRC）副委員長
  • 2018年02月 - 2021年08月, 米国内科学会日本支部, Public Relations Committee（PRC）委員
  • 2017年02月 - 2021年05月, 日本プライマリ・ケア連合学会, 若手医師部会 病院総合医チーム

研究活動情報

■ 受賞
  • 2026年06月 米国内科学会日本支部, ACP Japan Chapter Contribution Award

  • 2023年06月 米国内科学会日本支部, ACP Japan Chapter Young Leadership Award, 米国内科学会日本支部PRC委員長

  • 2021年06月 米国内科学会日本支部, ACP Japan Chapter Academic Award, ITC翻訳プロジェクト プロジェクトリーダー

  • 2021年06月 日本プライマリ・ケア連合学会, 日野原賞

  • 2016年03月 神戸市立医療センター中央市民病院, 後期研修医ベストレジデント

  • 2016年03月 神戸市立医療センター中央市民病院, ベストティーチャー賞

  • 2015年03月 神戸市立医療センター中央市民病院, ベストティーチャー賞

  • 2013年03月 神戸市立医療センター中央市民病院, 初期研修医ベストレジデント

■ 論文
  • Yurika Kitabayashi, Naoto Ishimaru, Masataka Ono, Shimpei Mizuki, Yohei Kanzawa, Takahiro Nakajima
    2026年07月, Journal of Infection and Chemotherapy
    研究論文（学術雑誌）

  • Yohei Kanzawa, Yayoi Tetsuou Tsukada, Kenta Ishibashi, Masataka Ono, Yui Matsushima, Motohiro Shingu, Hideki Saito, Koichi Tamita, Naoto Ishimaru
    2026年03月, Journal of General and Family Medicine
    [査読有り]
    神戸大学リポジトリ（Kernel）へのリンク

  • Naoto Ishimaru, Toshio Shimokawa, Masataka Ono, Shimpei Mizuki, Yohei Kanzawa, Takahiro Nakajima
    BACKGROUND: Tranexamic acid (TXA) is sometimes used to relieve sore throat discomfort from acute upper-respiratory tract infection (URTI), but its clinical effect has not been demonstrated in robust randomized controlled trials. METHODS: The tranexamic acid for URTI study is a randomized double-blinded clinical trial that was conducted between November 2023 and March 2025. Patients with URTI and a sore throat (18-65 years old) were randomized to receive either 1 g placebo (lactose) or 1 g preparation of 50% TXA. Randomization was stratified according to age (< 45 vs. ≥ 45 years) and baseline sore throat visual analog scale (VAS) score (< 50 vs. ≥ 50). Change in the proportion of patients with sore throat score more than a moderate level within a 2-h period after taking TXA was the primary outcome. We also examined the difference in sore throat VAS scale score between before and 2 h after TXA was taken. Data were analyzed using analysis of covariance, controlling for stratification factors. RESULTS: We analyzed the 17 participants assigned to each group (total = 34). The groups were not significantly different in the proportion of patients whose sore throat had a moderate or greater impact on their day-to-day life (TXA 41.2% vs. placebo 47.1%; p = 1.00). Similarly, they did not significantly differ in mean change of sore throat score on VAS within 30 min (TXA 17.3 vs. placebo 13.1; p = 0.49). No side effects were reported. CONCLUSION: TXA was not significantly better than a placebo at relieving acute URTI-associated sore throat. TRIAL REGISTRATION: UMIN000056394.
    2026年01月, Journal of general and family medicine, 27(1) (1), e70097, 英語, 国内誌
    研究論文（学術雑誌）

  • Kosuke Ishizuka, Taiju Miyagami, Yohei Kanzawa, Aiko Harada, Dai Aoki, Yoshiki Umezawa, Masataka Ono, So Sakamoto
    2025年09月, Journal of general and family medicine, 26(5) (5), 495 - 496, 英語, 国内誌

  • Mari Yamaoka, Yohei Kanzawa, Nobuya Sano, Masataka Ono, Shimpei Mizuki, Takahiro Nakajima, Naoto Ishimaru
    A 64-year-old man presented with abdominal bloating and a fever. Initial imaging revealed an abdominal aneurysm suspected to be an infected aortic aneurysm (IAA); therefore, antibiotic treatment was initiated. Blood culture confirmed group A Streptococcus (GAS). Follow-up computed tomography revealed aneurysm expansion, confirming the diagnosis of IAA. The patient survived the emergency surgery. IAA is a potentially fatal disease with a high risk of rupture. IAA is rarely caused by GAS and is a diagnostic challenge owing to non-specific symptoms and imaging findings. We herein review reports of GAS-caused IAA and highlight diagnostic and therapeutic dilemmas, including the optimal timing for surgery, which warrants further research.
    2025年08月, Internal medicine (Tokyo, Japan), 英語, 国内誌
    研究論文（学術雑誌）
    神戸大学リポジトリ（Kernel）へのリンク

  • Naoto Ishimaru, Takahiro Waki, Toshio Shimokawa, Shimpei Mizuki, Yohei Kanzawa, Takahiro Nakajima, Kenjiro Ito, Saori Kinami
    BACKGROUND AND OBJECTIVES: Hip fractures are associated with high morbidity and mortality. We compared the impacts of a hospitalist consultant model and hospitalist model on morbidity in patients with hip fractures with conventional orthopaedic surgeon-led care. METHOD: This retrospective cohort study included patients who underwent surgery for hip fractures between April 2017 and March 2022. The primary outcome was the rate of perioperative complications. Multivariate analysis was adjusted for age, gender and any significant variables shown in univariate analysis. RESULTS: Of the 982 patients, 329, 224 and 429 were treated within the orthopaedic department, the hospitalist consultant model and the hospitalist model, respectively. In adjusted analysis, time to surgery was shorter within the hospitalist model (odds ratio [OR]: -0.259; 95% confidence interval [CI]: -0.502 to -0.016), but there were no differences among groups in length of stay, complications or in-hospital mortality. DISCUSSION: A family physician-led hospitalist model might facilitate earlier surgery for hip fractures than a conventional care model.
    2025年06月, Australian journal of general practice, 54(6) (6), 400 - 406, 英語, 国際誌
    研究論文（学術雑誌）

  • Takahiro Minamii, Takahiro Nakajima, Shinpei Mizuki, Yohei Kanzawa, Naoto Ishimaru
    A 71-year-old woman with previously undiagnosed human T-lymphotropic virus type 1 (HTLV-1) infection presented with fever, urinary difficulties, acute abdominal pain, and severe acute kidney injury (AKI). Diagnostic evaluations confirmed acute pyelonephritis (APN) and acute focal bacterial nephritis (AFBN). Despite antibiotic treatment, she required temporary hemodialysis and eventually developed chronic kidney disease. This case highlights the importance of considering APN and AFBN as differential diagnoses in patients presenting with acute abdominal pain and severe AKI. It also underscores the need to investigate predisposing conditions. Notably, neuropathic bladder can be an isolated neurogenic manifestation of chronic HTLV-1 infection. Therefore, a thorough assessment of urinary dysfunction is essential in patients with APN and chronic HTLV-1 infection.
    2025年03月, Cureus, 17(3) (3), e81079, 英語, 国際誌
    研究論文（学術雑誌）

  • Naoto Ishimaru, Motohiro Shingu, Jun Ohnishi, Shimpei Mizuki, Yohei Kanzawa, Takahiro Nakajima, Saori Kinami
    Bacteremia due to Moraxella Catarrhalis is rare. An 85-year-old Japanese woman had productive cough, dyspnea, and fever. She had type 2 diabetes mellitus and chronic heart failure. Infiltration shown on chest radiography could be explained by heart failure or pneumonia. Initial blood culture yielded Gram-negative cocci, identified as M. catarrhalis. We therefore diagnosed cardiogenic pulmonary edema and M. catarrhalis pneumonia. M. catarrhalis has a high prevalence of β- lactamase production, so treatment comprised ampicillin/sulbactam. The clinical outcomes were favorable. Our case shows the importance of consideration of M. catarrhalis when patients with heart failure have pneumonia, and the importance of blood culture for such patients.
    2025年02月, Postgraduate medicine, 英語, 国際誌
    研究論文（学術雑誌）

  • Jun Ohnishi, Naoto Ishimaru, Toshio Shimokawa, Saori Kinami, Takahiro Nakajima, Yohei Kanzawa, Shimpei Mizuki
    BACKGROUND: Blood culture is important in the diagnosis of blood infections and the identification of treatment strategies. Increased contamination in blood culture is a reduction in quality of care. This retrospective observational study, set in an emergency department in Japan, aims to elucidate the contamination rate before and after the introduction of contamination prevention activities. METHODS: We compared the contamination rates before and one year after contamination prevention activities. Specifically, these activities included a novel and specific use of a blood culture cart and adherence to a checklist. The checklist included noting the actual site of collection, the method of disinfection, and whether gloves were worn. RESULTS: There were 1184 and 1129 blood culture samples before and after the preventive activities, respectively. The rates of contamination were 2.03% (95% Cl = 1.30% to 3.00%) and 1.24% (95% Cl = 0.68% to 2.07%), respectively. CONCLUSION: Prevention activities including specific use of a blood culture cart and careful adherence to a checklist were not associated with a significant decrease in contamination rate in our hospital. Further studies based in hospitals with greater rates of contamination may see higher rates of reduction.
    2025年02月, Journal of evaluation in clinical practice, 31(1) (1), e70024, 英語, 国際誌
    研究論文（学術雑誌）

  • Naoto Ishimaru, Toshio Shimokawa, Shimpei Mizuki, Yohei Kanzawa, Takahiro Nakajima, Nobuya Sano, Saori Kinami
    In hospitalized patients, dermatologist intervention can lead to rapid identification and treatment of skin disease. However, many medical centers lack a specialized dermatologist, so skin biopsies might instead be performed by hospitalists. We aimed to determine the impact of skin biopsies performed by hospitalists on the diagnosis of skin conditions. Included in this study were adult patients who had skin biopsies performed for skin conditions by hospitalists at our hospital between 2012 and 2022. We retrospectively analyzed the diagnostic contribution rate before and after skin biopsy. Skin biopsies were performed on 49 patients, with 37 patients (75.5%) having biopsy in one location, 5 patients (10.2%) in two locations, and 7 patients (14.3%) in three locations. The average age was 63.5 [20.2] years, 55% of the patients were male and 12% had an in-hospital dermatologist consultation prior to assessment. IgA vasculitis was suspected in 9 patients (18.4%), and vasculitis, erythema nodosum, and intravascular lymphoma were each suspected in 4 patients (8.2%), respectively. IgA vasculitis was ultimately diagnosed in 10 patients (20.4%), polyarteritis nodosa in 3 patients (6.1%), and erythema nodosa in 3 patients (6.1%). Skin biopsy performed by hospitalists had a diagnostic contribution of 75.5%, with a change in diagnosis of 30.6% and a change in therapy of 14.3%. There was no difference in the rate of treatment changes according to the type of skin condition. Hospitalist-performed skin biopsies are suggested by our results to be limited, but still informative in healthcare facilities without a dedicated dermatologist.
    2024年11月, Archives of dermatological research, 317(1) (1), 18 - 18, 英語, 国際誌
    研究論文（学術雑誌）

  • Naoto Ishimaru, Takahiro Waki, Toshio Shimokawa, Shimpei Mizuki, Jun Ohnishi, Yohei Kanzawa, Takahiro Nakajima, Tomonori Yano, Kenjiro Ito, Keisuke Oe, Saori Kinami
    Myocardial injury after non-cardiac surgery is due to ischaemia either during non-cardiac surgery or within 30 days after it. Our surveillance protocol includes hip fracture template and high-sensitivity troponin stratification, as recommended in European countries. Our retrospective study cohort included surgical patients for hip fracture at our hospital in Japan. The primary outcome was the rate of myocardial injury after non-cardiac surgery in comparison to patients managed with (213) and without (176) hip fracture template. The hip fracture template was used more in patients with myocardial injury after non-cardiac surgery than those without myocardial injury after non-cardiac surgery. When hip fracture template was used, patients had a higher likelihood of myocardial injury after non-cardiac surgery after adjusting for age, time to operation, diabetes mellitus, and chronic kidney disease (odds ratio 41.3; 95% confidence interval: 12.1, 259.6). Patients with myocardial injury after non-cardiac surgery had higher in-hospital mortality than those without myocardial injury after non-cardiac surgery, even in adjusted analysis. There was a high detection rate of myocardial injury after non-cardiac surgery when patients with hip fractures were managed with hip fracture template. Myocardial injury after non-cardiac surgery was associated with in-hospital mortality.
    2024年08月, Journal of perioperative practice, 17504589241268624 - 17504589241268624, 英語, 国際誌
    研究論文（学術雑誌）

  • Koki Hirose, Yohei Kanzawa, Nobuya Sano, Keishiro Tsuruta, Shimpei Mizuki, Takahiro Nakajima, Naoto Ishimaru, Saori Kinami
    Giant cell arteritis (GCA) can result in visual loss and other sequelae. An 81-year-old man presented with a one-week history of fever. He had bilateral temporal headache, jaw claudication, tenderness of the temporal arteries and a recent skin rash. A temporal artery biopsy showed typical GCA, but the symptoms were self-limiting. We continued close observation, without administering prednisolone treatment. Five months later, the symptoms did not recur, and prednisolone again was not administered. Our patient presented with an atypical course of GCA that created a clinical dilemma. The final diagnosis was self-limiting GCA.
    2024年08月, Internal medicine (Tokyo, Japan), 英語, 国内誌
    研究論文（学術雑誌）

  • Naoto Ishimaru, Takahiro Waki, Toshio Shimokawa, Shimpei Mizuki, Jun Ohnishi, Yohei Kanzawa, Takahiro Nakajima, Tomonori Yano, Kenjiro Ito, Shinji Matsushima, Saori Kinami
    2024年, Indian Journal of Orthopaedics
    研究論文（学術雑誌）

  • Daichi Umemoto, Yohei Kanzawa, Tomoko Nakamura, Ichizo Nishino, Shimpei Mizuki, Jun Ohnishi, Takahiro Nakajima, Naoto Ishimaru, Saori Kinami
    We herein report a case of immune-mediated necrotizing myopathy (IMNM) in a patient with microscopic polyangiitis (MPA). A 77-year-old Japanese woman presented with a 2-day history of proximal muscle weakness and myalgia, with elevated serum creatinine kinase (CK) levels. Findings of a muscle biopsy were compatible with IMNM; however, anti-SRP and anti-HMGCR antibodies were negative. She also had peripheral neuropathy with elevated serum MPO-ANCA titers, leading to a diagnosis of MPA. IMNM can be a pathological result of MPA muscle involvement.
    2023年10月, Internal medicine (Tokyo, Japan), 英語, 国内誌
    研究論文（学術雑誌）

  • Yohei Kanzawa, Hiroyuki Seto, Toshio Shimokawa, Takahiko Tsutsumi, Naoto Ishimaru, Saori Kinami, Yuichi Imanaka
    Objective: Aspiration pneumonia is a challenge in Japan, with many elderly citizens; however, there are insufficient experts on swallowing. Non-expert doctors may suspend oral intake for an overly long period because of the fear of further aspiration. We devised and modified an assessment protocol for swallowing function with reference to the Japanese and American practical guidelines for dysphagia. This study aimed to demonstrate clinical decision-making using the protocol by reporting the results of decisions on the safe and timely restart of adequate food intake for patients with aspiration pneumonia. Patients and Methods: This comparative retrospective study included 101 patients hospitalized with aspiration pneumonia between April 2015 and November 2017. We compared the parameters of patients for whom decisions on resumption of oral intake were aided by our protocol against those of patients from the previous year when the protocol was not used. We counted the days until either resumption of oral intake or events of aspiration/choking. Results: The duration of days until oral intake in the two groups was 1.64 ± 2.34 days in the protocol group (56 patients) and 2.09 ± 2.30 days in the control group (45 patients) (P=0.52). The adverse events of aspiration/choking were less frequent in the protocol group (5 vs. 15, odds ratio (OR) 0.32, P<0.001) as compared to the control group. The protocol group showed a significant reduction in aspiration/choking (OR 0.19, P<0.01). Conclusion: Clinical decision-making based on the protocol seems to help non-expert doctors make informed decisions regarding resuming oral intake after aspiration pneumonia.
    2023年04月, Journal of rural medicine : JRM, 18(2) (2), 62 - 69, 英語, 国内誌
    研究論文（学術雑誌）

  • Yohei Kanzawa, Naoto Ishimaru, Toshio Shimokawa, Saori Kinami, Yuichi Imanaka
    OBJECTIVE: In Japan, the benefits of hospitalist physician-led care after heart failure have not been sufficiently demonstrated. We evaluated quality of care by the general internal medicine hospitalist (GIM-H) system for patients after acute heart failure and compared it with care by cardiologists. METHODS: This retrospective cohort study enrolled adult patients from within a two-year period who were admitted to our institution for heart failure. Primary outcome measures were medico-economic indicators: length of hospital stay and medical costs. Secondary outcomes included readmission within 30 days of discharge, death within 30 days of admission, rate of prescription of ACEI/ARB and beta-blockers for heart failure with reduced left ventricular ejection fraction, and the percentage of patients receiving bespoke written treatment plans after discharge. This was thought to represent quality of heart failure-specific care. Outcomes between the groups were compared by adjusting for background factors using a propensity score. RESULTS: We enrolled 404 patients, and 81 were assigned to each group after matching (mean age: 86 years, female: 64.2%, mean left ventricular ejection fraction: 53.2%). The GIM-H-treated group had a significantly shorter hospital stay (13.7 days vs. 21.8 days, P<0.001), a significantly lower total medical cost (618,805 JPY vs. 867,857 JPY, P<0.05) but a higher medical cost per day (48,010 JPY vs 42,813 JPY, P<0.05) than the cardiologist-treated group. Other indicators were not significantly different. CONCLUSIONS: : GIM-H physicians in Japan are suggested to be useful and effective in care of patients with heart failure. The hospitalist system may positively impact the health economic outcomes of such patients.
    2023年03月, Hospital practice (1995), 英語, 国際誌
    研究論文（学術雑誌）

  • Naoto Ishimaru, Toshio Shimokawa, Takahiro Nakajima, Yohei Kanzawa, Saori Kinami
    OBJECTIVES: To determine the incidence of bacteremia in patients with DKA. METHODS: We conducted a cross-sectional study of patients aged 18 years and older with a principal diagnosis of DKA or hyperglycemic hyperosmotic syndrome (HHS) who presented to our community hospital between 2008 and 2020. Using medical records from initial visits, we retrospectively calculated the incidence of bacteremia. This was defined as the percentage of subjects with positive blood cultures except for those with contamination. RESULTS: Among 114 patients with hyperglycemic emergency, two sets of blood cultures were collected in 45 of 83 patients with DKA (54%), and 22 of 31 patients with HHS (71%). The mean age of patients with DKA was 53.7 years (19.1) and 47% were male, while the mean age of patients with HHS was 71.9 years (14.9) and 65% were male. The incidences of bacteremia and blood culture positivity were not significantly different between patients with DKA and those with HHS (4.8% vs. 12.9%, P = 0.21 and 8.9% vs. 18.2%, P = 0.42, respectively). Urinary tract infection was the most common concomitant infection of bacteria, with E. coli as the main causative organism. CONCLUSION: Blood cultures were collected in approximately half of the patients with DKA, despite a nonnegligible number of them testing positive in blood culture. Promoting awareness of the need for taking blood culture is imperative for the early detection and management of bacteremia in patients with DKA. CLINICAL TRIAL REGISTRATION: UMIN trial ID - UMIN000044097; jRCT trial ID - jRCT1050220185.
    2023年03月, Hospital practice (1995), 51(2) (2), 1 - 6, 英語, 国際誌
    研究論文（学術雑誌）

  • Masahiro Kaneko, Naoto Ishimaru, Takahiro Nakajima, Yohei Kanzawa, Hiroyuki Seto, Saori Kinami, Tsukasa Osaki, Masayoshi Souri, Akitada Ichinose
    Autoimmune factor XIII/13 deficiency (aFXIII deficiency) is a rare hemorrhagic disorder, for which typical guideline-directed treatment is aggressive immunosuppressive therapy. Approximately 20% of patients are over 80 years old; however, and optimum management of such patients has not reached consensus. Our elderly patient had massive intramuscular hematoma, and aFXIII deficiency was diagnosed. The patient opted against aggressive immunosuppressive therapy, so he was managed with conservative treatment only. Thorough survey of other correctable causes of bleeding and anemia is also required in similar cases. Our patient's serotonin-norepinephrine reuptake inhibitor use and multivitamin deficiency (vitamin C, B12 and folic acid) were revealed to be aggravating factors. Fall prevention and muscular stress prevention are also important in elderly patients. Our patient had two relapses of bleeding within 6 months, which were improved spontaneously by bed rest without factor XIII replacement therapy or blood transfusion. Conservative management may be preferred for frail and elderly patients with aFXIII deficiency when they opt against standard therapy.
    2023年02月, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 英語, 国際誌
    研究論文（学術雑誌）

  • Hazuki Fujimoto, Yohei Kanzawa, Hidemine Senba, Tetsuo Washio, Yukiko Kato, Kei Kawano, Shimpei Mizuki, Jun Ohnishi, Takahiro Nakajima, Naoto Ishimaru, Saori Kinami
    An 83-year-old woman with asymptomatic pulmonary sarcoidosis presented to our hospital with fever and malaise for three months. Abdominal CT showed splenomegaly, and bone marrow examination revealed non-caseating granulomas. Pancytopenia was diagnosed due to bone marrow and splenic lesions of sarcoidosis. Steroid pulses were administered, but the patient died without response to treatment. Pathological autopsy results showed non-caseating granulomas and hemophagocytosis in the spleen and bone marrow. This suggested hemophagocytic syndrome, which was not suspected before death, in addition to sarcoidosis. In patients with splenomegaly and pancytopenia with history of pulmonary sarcoidosis, hemophagocytic syndrome should be considered in differential diagnosis.
    2023年01月, Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 英語, 国際誌
    研究論文（学術雑誌）

  • Masahiro Kaneko, Naoto Ishimaru, Toshio Shimokawa, Takahiro Nakajima, Yohei Kanzawa, Hiroyuki Seto, Saori Kinami
    OBJECTIVES: The aim of this study was to examine whether the distance between the skin and the renal pelvis affects the detection of costovertebral angle (CVA) tenderness in patients with acute focal bacterial nephritis (AFBN). METHODS: We retrospectively reviewed the charts of our patients between April 2013 and June 2019 who were diagnosed as having AFBN. Diagnosis was based on ultrasound or computed tomography with contrast, revealing at least one wedge-shaped area of decreased vascularity and confirmation of fever not attributable to another condition. RESULTS: We extracted 23 cases, all Japanese (mean age 60.0 years old [range 45-81 years], 7 males, 16 females). CVA tenderness was present in 8 of these 23 patients. Receiver operating characteristic curves were drawn to evaluate the ability to differentiate skin-to-renal pelvis distance (SPD), body mass index, and age. Only SPD was a useful predictor of CVA tenderness, and 66 mm was determined as the optimal cutoff point (area under the receiver operating characteristic curve 0.858, 95% confidence interval 0.70-1.00). Logistic regression analysis was performed with CVA tenderness as a dependent variable, and SPD, body mass index, and age as explanatory variables. SPD was an independent predictive variable of CVA tenderness (P = 0.038, odds ratio 0.76, 95% confidence interval 0.590-0.986). CONCLUSIONS: CVA tenderness showed low yield in the diagnosis of AFBN in patients with longer SPD. Its use for diagnosis in obese patients may therefore be limited.
    2023年01月, Southern medical journal, 116(1) (1), 20 - 25, 英語, 国際誌
    研究論文（学術雑誌）

  • Naoto Ishimaru, Yohei Kanzawa, Takahiro Nakajima, Kayoko Okamura, Eiichiro Sando, Isao Ito, Saori Kinami, Hisashi Ohnishi
    Specific antibody deficiency against pneumococcal serotypes was detected in a patient with recurrent episodes of fever. A 21-year-old man presented with a two-month history of recurrent episodes of fever and shaking chills. He was diagnosed with recurrent episodes of pneumonia caused by Streptococcus pneumoniae serotype 19A and treated with amoxicillin. Serotype-specific antibodies were not produced against most of the serotypes, which were consistent with moderate specific antibody deficiency. After pneumococcal 13-valent conjugate vaccination and pneumococcal polysaccharide vaccination, he adequately responded to the infecting serotype with an antibody titer of 1.1 µg/mL. There were eventually no recurrent episodes of fever with pneumonia.
    2022年11月, Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 英語, 国際誌
    研究論文（学術雑誌）

  • Naoto Ishimaru, Satoshi Suzuki, Toshio Shimokawa, Kenji Iijima, Yohei Kanzawa, Takahiro Nakajima, Saori Kinami
    SAGE Publications, 2022年09月, Journal of Integrative and Complementary Medicine, 28(9) (9), 768 - 774
    研究論文（学術雑誌）

  • Yohei Kanzawa, Jun Ohnishi, Naoto Ishimaru, Saori Kinami
    Wiley, 2022年05月, Journal of General and Family Medicine
    研究論文（学術雑誌）

  • Hiroyuki Seto, Naoto Ishimaru, Jun Ohnishi, Yohei Kanzawa, Takahiro Nakajima, Toshio Shimokawa, Yuichi Imanaka, Saori Kinami
    Objective This study evaluated the effectiveness of a multidisciplinary team deprescribing intervention to reduce polypharmacy and potentially inappropriate medications (PIMs) in elderly orthopedic inpatients. Methods In this single-center retrospective observational study, orthopedic inpatients ≥75 years old and prescribed ≥6 different medications were enrolled as participants. Interventions comprised multidisciplinary team-led polypharmacy screening and suggestions regarding deprescribing any unnecessary medications during hospital stays. The primary outcome was reduction in the mean number of regular medicines and PIMs. Secondary outcomes included falls, delirium, and other adverse events during hospitalization as well as emergency department visits or unplanned hospital admissions within six months after discharge. Results After propensity score matching, 184 patients (intervention group, n=92; control group, n=92) were included in the analysis. The mean patient age was 83 years old. The mean number of prescribed medications and PIMs at admission were similar in both groups. The mean change in the number of regular medicines was -1.4 (standard deviation [SD], 2.3) in the intervention group and +0.2 (SD, 1.8) in the control group (p<0.001). The mean change in the number of PIMs was -0.5 (SD, 0.9) in the intervention group and +0.1 (SD, 0.8) in the control group (p<0.001). In-hospital adverse events other than falls and delirium were significantly less common in the deprescribing intervention group than in the control group. Conclusion Deprescribing intervention by our multidisciplinary team seems to have been effective in reducing the number of prescribed medicines and PIMs in elderly orthopedic inpatients, with some accompanying reduction in certain adverse events.
    2022年01月, Internal medicine (Tokyo, Japan), 英語, 国内誌
    研究論文（学術雑誌）

  • Mari Yamaoka, Yohei Kanzawa, Shun Tatehara, Koji Sasaki, Shimpei Mizuki, Jun Ohnishi, Takahiro Nakajima, Naoto Ishimaru, Saori Kinami
    Hereditary hemorrhagic telangiectasia (HHT) is a risk of infection, such as by brain abscess associated with pulmonary arteriovenous malformations. However, association between HHT and recurrent erysipelas is not well described. HHT can cause vessel malformations in organs, leading to various serious outcomes. Prophylactic treatment is effective, but many people with HHT are undiagnosed. HHT is not described as a risk factor for soft tissue infection, but may increase the risk of serious infections requiring hospitalization. Our 72-year-old female patient was admitted for recurrent erysipelas. Pulmonary nodules indicated pulmonary arteriovenous fistula on chest computed tomography. By recognizing this combination, although seemingly unrelated problems, we could diagnose HHT and the patient could receive adequate treatment to prevent life-threatening events. The recurrent erysipelas was likely associated with HHT. Recurrent erysipelas is an important presentation which may facilitate early diagnosis of HHT.
    2022年, Le infezioni in medicina, 30(1) (1), 129 - 133, 英語, 国際誌

  • Nina Omoto, Yohei Kanzawa, Naoto Ishimaru, Saori Kinami
    Serotonin syndrome is a potentially life-threatening adverse reaction from therapeutic drug use, intentional self-poisoning, or inadvertent interactions between drugs. We report a case of the serotonin syndrome after an overdose of a commonly available over-the-counter cough medicine, Shin CONTAC sekidome daburu jizokusei. Over-the-counter drugs containing dextromethorphan may, in rare cases, cause health problems requiring hospitalization or worse. An appropriate explanation from the pharmacist at the time of purchase, although not mandatory, is recommended.
    2022年01月, Journal of general and family medicine, 23(1) (1), 38 - 40, 英語, 国内誌

  • Yasutaka Tsujimoto, Yohei Kanzawa, Naoto Ishimaru, Saori Kinami
    2021年10月, Internal medicine (Tokyo, Japan), 英語, 国内誌
    研究論文（学術雑誌）

  • Naoto Ishimaru, Yohei Kanzawa, Takahiro Nakajima, Hiroyuki Seto, Masayuki Ando, Saori Kinami
    Our patient had appendicitis complicated by Chlamydia trachomatis-induced Fitz-Hugh-Curtis syndrome and cervicitis. Differential diagnosis was challenging. A 22-year-old Japanese woman was febrile and presented with vomiting and subsequent abdominal pain. She had unprotected sexual intercourse with multiple partners. She had high Alvarado score and lack of cervical motion pain, despite cervical inflammation. Noncontrast CT showed enlarged appendix. Laparoscopic appendectomy revealed acute suppurative appendicitis and perihepatic adhesion. Cervical PCR assay was positive for C. trachomatis. She remained febrile but defervesced after azithromycin therapy. Clinicians should confirm whether females with abdominal pain are sexually active in view of screening for C. trachomatis.
    2021年09月, Journal of general and family medicine, 22(5) (5), 288 - 290, 英語, 国内誌

  • Motohiro Shingu, Naoto Ishimaru, Jun Ohnishi, Shimpei Mizuki, Yohei Kanzawa, Kei Kawano, Takahiro Nakajima, Nobuya Sano, Saori Kinami
    Hemolytic anemia is a rarely occurring manifestation of native valve infective endocarditis. We herein report an afebrile patient with hemolytic anemia caused by Cardiobacterium hominis endocarditis. A 60-year-old Japanese man had a history of aortic root replacement and the gradual onset of general fatigue. He had hemolytic anemia. Blood cultures detected C. hominis. A transthoracic echocardiogram showed aortic valve vegetation and periannular abscess with perforation of the non-coronary cusp. Intravascular hemolysis recovered after antimicrobial therapy, surgical removal of the vegetation and abscess, and aortic valve replacement. Subacute endocarditis should be considered if patients develop hemolytic anemia with signs of chronic inflammation without a fever.
    2021年05月, Internal medicine (Tokyo, Japan), 60(21) (21), 3489 - 3495, 英語, 国内誌
    研究論文（学術雑誌）

  • Saki Hieda, Naoto Ishimaru, Jun Ohnishi, Shimpei Mizuki, Yohei Kanzawa, Kei Kawano, Takahiro Nakajima, Saori Kinami
    Hyperosmolar hyperglycemic syndrome is a life-threatening diabetic emergency that manifests as altered mental status. An otherwise healthy 40-year-old man presented to our emergency department with headache and severe hypertension. Brain magnetic resonance imaging showed evidence of posterior reversible encephalopathy syndrome, a usually reversible neurological syndrome characterized by subcortical vasogenic oedema. This first reported case details posterior reversible encephalopathy syndrome concurrent with hyperosmolar hyperglycemic syndrome. Prompt diagnosis and management were essential to avoid non-reversible consequences.
    2021年04月, The American journal of emergency medicine, 英語, 国際誌

  • Naoto Ishimaru, Jun Ohnishi, Hiroyuki Seto, Yohei Kanzawa, Nobuya Sano, Saori Kinami
    A 23-year-old man had an 8-day history of fatigue and dry cough and papulo-nodular reactions on his extensive tattoos. Chest radiography revealed several small granular shadows, and a transbronchial lung biopsy showed non-caseating epithelioid cell granuloma. A skin biopsy of the tattooed area showed histiocytic infiltrates with phagocytized tattoo pigment. Antibody tests for hepatitis C virus were positive. The patient was successfully treated with corticosteroid therapy, and after inflammation was suppressed, he received delayed anti-viral therapy. Sarcoidosis should be considered as a concurrent condition if papules are presented on the tattoos of patients with hepatitis C.
    2021年02月, Internal medicine (Tokyo, Japan), 60(4) (4), 645 - 650, 英語, 国内誌
    研究論文（学術雑誌）

  • Yukiko Shiraishi, Yohei Kanzawa, Naoto Ishimaru, Saori Kinami
    2021年02月, Internal medicine (Tokyo, Japan), 英語, 国内誌
    研究論文（学術雑誌）

  • Mei Nakatsuji, Naoto Ishimaru, Jun Ohnishi, Shimpei Mizuki, Yohei Kanzawa, Kei Kawano, Takahiro Nakajima, Masaru Kuroda, Nobuya Sano, Saori Kinami
    SAGE Publications Ltd, 2021年, Journal of Scleroderma and Related Disorders, 英語
    研究論文（学術雑誌）

  • Hiroaki Nishioka, Yohei Kanzawa
    Antihistamines are known risk factors for restless legs syndrome (RLS). However, reports on RLS associated with fexofenadine or its combinations are rare. Here, we report a 30-year-old woman with RLS that was induced by fexofenadine/pseudoephedrine. She had been taking fexofenadine/pseudoephedrine for three months and felt a strong urge to move her legs at night, which was relieved by movement. Her condition improved by taking pramipexole, which she discontinued subsequently because of dizziness. One month later, she quitted taking fexofenadine/pseudoephedrine, after which her symptoms disappeared a week later. This case study demonstrates that RLS can be induced by fexofenadine/pseudoephedrine and we should always consider the possibility of drug-induced RLS.
    2020年11月, Journal of general and family medicine, 21(6) (6), 256 - 257, 英語, 国内誌

  • Naoto Ishimaru, Saori Kinami, Toshio Shimokawa, Hiroyuki Seto, Yohei Kanzawa
    Introduction: This study aimed to clarify the accuracy of an in-hospital mortality prediction score for patients with hypothermia. The score consists of five variables (age ≥70 years, mean arterial pressure <90 mm Hg, pH < 7.35, creatinine >1.5 mg/dL, and confusion). In contrast to the previously reported population in southern Israel, a desert climate, we apply the score system to a Japanese humid subtropical climate. Methods: The study included patients with a principal diagnosis of hypothermia who were admitted to our community hospital between January 2008 and January 2019. Using the medical records from initial visits, we retrospectively calculated in-hospital mortality prediction scores along with sensitivity and specificity. Results: We recruited 69 patients, 67 of which had analyzable data. Among them, the in-hospital mortality rate was 25.4%. Hypothermia was defined as mild (32-35°C) in 34 cases (50.7%), moderate (28-32°C) in 23 cases (34.3%), and severe (<28°C) in 10 cases (14.9%). The C-statistics of the in-hospital mortality prediction score was 0.703 (95% confidence interval, 0.55-0.84) for thirty-day survival prediction. After adjustment of the cutoff point of each item with ROC analysis and selection of the variants, the C-statistics of the in-hospital mortality prediction score rose to 0.81 (95% confidence interval, 0.69-0.92). Conclusion: The in-hospital mortality prediction scores showed slightly less predictive value than those in the previous report. With some modification, however, the score system could still be applied efficiently in the humid Japanese subtropical climate. An appropriate management strategy could be established based on the predicted mortality risk.
    2020年07月, Journal of general and family medicine, 21(4) (4), 134 - 139, 英語, 国内誌
    研究論文（学術雑誌）

  • Masahiro Kaneko, Naoto Ishimaru, Takahiro Nakajima, Yohei Kanzawa, Hiroyuki Seto, Saori Kinami
    Japanese spotted fever (JSF) is an uncommon but potentially fatal infection transmitted by tick bites. We herein report a fulminant case of JSF infection that occurred in an immunocompetent adult that was complicated by disseminated intravascular coagulation and hemophagocytic lymphohistiocytosis (HLH). We discuss the difficulty in making the diagnosis and identifying the complication of HLH in our patient. HLH is a rare complication of rickettsiosis, and this is the first reported case in English of JSF complicated by HLH in an immunocompetent adult. Secondary HLH caused by rickettsiosis requires a different treatment from primary HLH. Rickettsiosis must therefore be considered in patients with HLH.
    2020年02月, Internal medicine (Tokyo, Japan), 59(3) (3), 445 - 451, 英語, 国内誌
    研究論文（学術雑誌）

  • Jun Ohnishi, Naoto Ishimaru, Hiroyuki Seto, Yohei Kanzawa, Saori Kinami
    A 65-year-old Japanese man was admitted to our hospital with fever and inflammation of the right ankle. We initiated antibiotics on suspicion of cellulitis. After no clinical improvement, we performed magnetic resonance imaging, which showed a fluid collection in the flexor hallucis longus (FHL) tendon sheath. Synovial fluid analysis revealed monosodium uric crystals. Final diagnosis was FHL tendonitis secondary to gout proven by synovial fluid analysis. To our knowledge, this is the first case report of FHL tendonitis caused by gout. When ankle inflammation is examined in clinical situations, FHL tendonitis caused by gout should be considered.
    2020年01月, Journal of the American Podiatric Medical Association, 110(1) (1), Article8, 英語, 国際誌
    研究論文（学術雑誌）

  • Necrotizing fasciitis and sepsis caused by Aeromonas hydrophila.
    Yasutaka Tsujimoto, Yohei Kanzawa, Hiroyuki Seto, Takahiro Nakajima, Naoto Ishimaru, Takahiro Waki, Saori Kinami
    Aeromonas hydrophila (A. hydrophila) occasionally causes necrotizing fasciitis (NF) and sepsis in immunocompromised hosts. NF is associated with high mortality. In cases of septic shock due to A. hydrophila, mortality is nearly 100%. Our 47-year-old male patient was diagnosed with NF and septic shock due to A. hydrophila. He had not been exposed to fresh or slightly salty water, which is where the bacterium is typically found, so its origin in this case is unclear. This is the first known case in which the patient was able to be completely cured without amputation. NF was suspected from his sepsis, medical history including alcoholic cirrhosis, and a severely poor general condition, but his skin lesions were mild. We promptly made an exploratory incision and debrided his legs. NF could then be diagnosed. At an early stage, A. hydrophila was recognized as a possible pathogen of NF because of the patient's medical background and the Gram stain findings of intraoperative exudate. Minocycline in addition to carbapenem and vancomycin plus clindamycin were administered as empiric therapy. When A. hydrophila was detected in the blood culture, ciprofloxacin was administered as definitive therapy. Successful treatment of NF requires early diagnosis, prompt debridement from onset and adequate empirical antibiotic therapy.
    2019年12月, Le infezioni in medicina, 27(4) (4), 429 - 435, 英語, 国際誌
    研究論文（学術雑誌）

  • Naoto Ishimaru, Saori Kinami, Toshio Shimokawa, Yohei Kanzawa
    Objective Kikyo-to (KKT) is a fixed combination of glycyrrhiza root and platycodon root extracts. It is an herbal medicine traditionally used in Japan for relieving sore throat associated with acute upper respiratory tract infection (URTI). No controlled studies have yet demonstrated its effect, however. We investigated the efficacy of KKT on sore throat associated with acute URTI. Methods Patients with sore throat who were diagnosed with URTI at the General Medicine Department Office, Akashi Medical Center Hospital, between December 2017 and May 2018 were enrolled. Participants were randomly assigned to two groups at a 1:1 ratio, with stratification by age and sore throat score on a Visual Analogue Scale (VAS), to receive 2.5 g of either KKT or a placebo. Participants and investigators were blinded to group allocation. The primary outcome was the change in sore throat score on VAS 10 minutes after KKT administration. Secondary outcomes were the impact of the sore throat on daily life (none, mild, moderate, and severe) at 10 minutes after administration. Results Thirty-five participants were assigned to each group (n=70, total). The difference in the mean change of sore throat score according to VAS within 10 minutes between the two groups was not statistically significant (KKT 14.40 vs. placebo 17.00; p=0.39). The proportion of patients with a moderate or greater impact of their sore throat on their daily life was also not significantly different between the groups (KKT 22.9% vs. placebo 40.0%; p=0.20). Patients reported no side effects. Conclusion KKT did not significantly relieve sore throat associated with acute URTI compared with placebo.
    2019年09月, Internal medicine (Tokyo, Japan), 58(17) (17), 2459 - 2465, 英語, 国内誌
    研究論文（学術雑誌）

  • Naoto Ishimaru, Yohei Kanzawa, Hiroyuki Seto, Saori Kinami
    We herein report a patient with syphilitic cervicitis and cervical cancer presenting as oropharyngeal syphilis. A 31-year-old Japanese woman with a history of unprotected vaginal and oral sex visited our hospital with right submandibular adenomas and erythema in the extremities. The fornix uteri was red, with a nodule noted. The rapid plasma reagin ratio was 1:3. She was diagnosed with syphilitic cervicitis and treated with amoxicillin for four weeks. Initial cervical cytology showed cells with mild nuclear enlargement, which was thought to be metaplasia associated with syphilis. Repeated cytology a month later showed a high-grade squamous intraepithelial lesion. A punch biopsy of the lesion led to the pathological diagnosis of cervical carcinoma in situ. We performed cervical conization, and no recurrence occurred. Human papillomavirus (HPV) immunostaining was positive in the lesion. Mucosal lesions are an infrequently reported symptom of syphilis. When oropharyngeal lesions are found, the sexual history should be ascertained, and the patient should be screened for sexually transmitted diseases. HPV is especially significant because of its association with cervical cancer. Coinfection of HPV with cervical cancer must be ruled out during follow-up for women when oropharyngeal syphilis involves genital lesions.
    2019年08月, Internal medicine (Tokyo, Japan), 58(15) (15), 2251 - 2255, 英語, 国内誌
    研究論文（学術雑誌）

  • Masaki Kobatake, Naoto Ishimaru, Yohei Kanzawa, Hiroyuki Seto, Saori Kinami
    In posterior reversible encephalopathy syndrome (PRES) triggered by scleroderma renal crisis (SRC), modulation and adherence in immunosuppressive therapy are key for avoiding recurrence, complications, and death. A patient with polymyositis (PM)/systemic sclerosis (SSc) overlap syndrome developed PRES triggered by SRC. To our knowledge, this is the first report of a case with PRES associated with PM/SSc overlap syndrome. This manifested as altered mental status and headaches. Vasogenic edema was seen by magnetic resonance imaging in the brainstem and cerebral white matter. Antihypertension therapy resulted in improvement in both neurological symptoms and blood pressure (BP). Reversible clinical course and radiological change were consistent with PRES diagnosis. Here, the importance of BP maintenance and removal of precipitating factors of PRES is shown.
    2019年07月, European journal of rheumatology, 6(3) (3), 158 - 160, 英語, 国際誌
    研究論文（学術雑誌）

  • Liver abscess with Citrobacter koseri bacteremia.
    Yohei Kanzawa, Naoto Ishimaru, Hiroyuki Seto, Takahiko Tsutsumi, Saori Kinami
    Citrobacter koseri is a rare cause of liver abscess with two reported cases in diabetic patients. We report a rare case of C. koseri liver abscess with C. koseri bacteremia in an elderly male with chronic kidney disease. He presented vomiting and weakness without any other signs. He was diagnosed with liver abscess by ultrasound, and blood culture showed C. koseri growth. The patient was treated effectively with a course of antibiotics and drainage. When C. koseri is isolated in patients with comorbidity, such as chronic kidney disease, we should consider the possibility of abscess including liver abscess and utilize a combined treatment of drainage and course of antibiotics for mixed infection.
    2018年09月, Le infezioni in medicina, 26(3) (3), 266 - 269, 英語, 国際誌
    研究論文（学術雑誌）

  • Yohei Kanzawa, Yukihiro Imai, Yasushi Mizuno, Hiroaki Nishioka
    Testicular vasculitis is a rare condition and little is known about its morphological features. Herein, we report a case of testicular lymphocytic vasculitis, which is rarely documented, in an elderly man. He presented with left testicular swelling and fever, but without any signs of other organ involvement. He was effectively treated with prednisolone and azathioprine. This case report offers information related to the disease course and the importance of biopsy.
    2017年07月, Modern rheumatology, 27(4) (4), 705 - 707, 英語, 国際誌
    研究論文（学術雑誌）

  • Yohei Kanzawa, Yasushi Mizuno, Yukihiro Imai, Hiroaki Nishioka
    The detection of abnormalities of the cranial arteries on magnetic resonance imaging (MRI) is useful for the diagnosis of giant cell arteritis (GCA). However, reports on the veins of GCA patients are rare. We report the case of an elderly woman with GCA who presented with facial edema. She presented with a one month history of headache and facial edema. After MRI and enhanced computed tomography revealed delayed blood flow in the left jugular vein, a temporal artery biopsy was performed. She was diagnosed with GCA based on the biopsy findings. Following corticosteroid therapy, her symptoms and venous flow improved. The present case indicates that delayed jugular venous flow can occur in GCA patients with facial edema.
    2016年, Internal medicine (Tokyo, Japan), 55(15) (15), 2077 - 80, 英語, 国内誌
    研究論文（学術雑誌）

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  • Clinician Update : ホスピタリストが押さえておくべき20論文をセレクト 拡大版(2)
    官澤 洋平, 石丸 直人
    メディカル・サイエンス・インターナショナル, 2022年, Hospitalist = ホスピタリスト, 10(2) (2), 370 - 377, 日本語

  • 日本の心不全入院診療における病院総合医のインパクト 後方視的コホート研究
    官澤 洋平, 水木 真平, 大西 潤, 河野 圭, 中島 隆弘, 石丸 直人, 木南 佐織, 今中 雄一
    (一社)日本プライマリ・ケア連合学会, 2021年05月, 日本プライマリ・ケア連合学会学術大会, 12回, np222 - np222, 日本語

  • 市販の鎮咳去痰薬の過量内服を契機としたセロトニン症候群の一例
    尾本 仁那, 官澤 洋平, 水木 真平, 大西 潤, 河野 圭, 中島 隆弘, 石丸 直人, 木南 佐織
    (一社)日本プライマリ・ケア連合学会, 2021年05月, 日本プライマリ・ケア連合学会学術大会, 12回, np460 - np460, 日本語

  • 糖尿病性ケトアシドーシス患者における菌血症発症率
    石丸直人, 水木真平, 大西潤, 官澤洋平, 河野圭, 中島隆弘, 木南佐織
    2021年, 日本プライマリ・ケア連合学会学術大会(Web), 12th

  • Clinician Update : ホスピタリストが押さえておくべき20論文をセレクト
    官澤 洋平, 石丸 直人
    2021年, 9(1) (1), 256 - 263, 日本語

  • 確定診断に時間を要した急性僧帽弁逆流(MR)の一例の診断過程を振り返る
    鶴田慧司郎, 石丸直人, 大西潤, 河野圭, 官澤洋平, 水木真平, 中島隆弘, 木南佐織
    2021年, 日本病院総合診療医学会雑誌(Web), 17

  • 丹毒での入院を契機に遺伝性出血性毛細血管拡張症を診断し専門治療につなげた一例
    山岡茉莉, 官澤洋平, 山崎菜々美, 小野雅敬, 河野圭, 水木真平, 大西潤, 中島隆弘, 石丸直人, 木南佐織
    2021年, 日本病院総合診療医学会雑誌(Web), 17

  • MULTIDISCIPLINARY TEAM INTERVENTION FOR ELDERLY ORTHOPEDIC INPATIENTS AND ITS IMPACT ON POLYPHARMACY AND POTENTIALLY INAPPROPRIATE MEDICATIONS
    Hiroyuki Seto, Toshio Shimokawa, Jun Ohnishi, Yohei Kanzawa, Kei Kawano, Takahiro Nakajima, Naoto Ishimaru, Saori Kinami, Yuichi Imanaka
    2020年07月, JOURNAL OF GENERAL INTERNAL MEDICINE, 35(SUPPL 1) (SUPPL 1), S203 - S203, 英語
    研究発表ペーパー・要旨（国際会議）

  • 運航後の船舶座礁:クラミジアによるFitz-Hugh-Curtis syndrome(FHCS)に虫垂炎を合併した一例
    石丸直人, 安藤正恭, 水木真平, 大西潤, 官澤洋平, 河野圭, 中島隆弘, 世戸博之, 木南佐織
    2020年, 日本プライマリ・ケア連合学会学術大会(Web), 11th

  • 特異的な症状に乏しく,初期診断が困難であった感染性大動脈瘤の一例
    田邊皓, 中島隆弘, 大西潤, 瀬戸博之, 官澤洋平, 河野圭, 石丸直人, 木南佐織
    2020年, 日本プライマリ・ケア連合学会学術大会(Web), 11th

  • Clinician Update : ホスピタリストが押さえておくべき20論文をセレクト
    官澤 洋平, 石丸 直人
    2020年, 8(3) (3), 584 - 591, 日本語

  • Clinician Update : ホスピタリストが押さえておくべき20論文をセレクト
    官澤 洋平, 石丸 直人
    2020年, 8(4) (4), 788 - 795, 日本語

  • Clinician Update : ホスピタリストが押さえておくべき20論文をセレクト
    官澤 洋平, 石丸 直人
    2020年, 8(2) (2), 338 - 345, 日本語

  • Clinician Update : ホスピタリストが押さえておくべき20論文をセレクト
    官澤 洋平, 石丸 直人
    2019年, 7(3) (3), 636 - 643, 日本語

  • Clinician Update : ホスピタリストが押さえておくべき20論文をセレクト
    官澤 洋平, 石丸 直人
    2019年, 7(4) (4), 928 - 935, 日本語

  • Clinician Update : ホスピタリストが押さえておくべき20論文をセレクト
    官澤 洋平, 石丸 直人
    2019年, 7(1) (1), 184 - 191, 日本語

  • Clinician Update : ホスピタリストが押さえておくべき20論文をセレクト
    官澤 洋平, 石丸 直人
    2019年, 7(2) (2), 420 - 427, 日本語

  • 官澤 洋平, 石丸 直人
    株式会社医学書院, 2018年12月01日, Hospitalist, 6(4) (4), 1064 - 1071

  • 官澤 洋平, 石丸 直人
    株式会社医学書院, 2018年09月01日, Hospitalist, 6(3) (3), 772 - 779

  • ビタミンB12欠乏によりジストニアを生じた引きこもりの一例
    世戸博之, 藤井千尋, 官澤洋平, 石丸直人, 木南佐織
    2018年, 日本病院総合診療医学会雑誌, 14(1) (1)

  • 刺青上の丘疹結節状反応を契機にサルコイドーシスと診断した慢性C型肝炎の一例
    大西潤, 石丸直人, 官澤洋平, 世戸博之, 木南佐織
    2018年, 日本プライマリ・ケア連合学会学術大会抄録集, 9th

  • アスペルギルス硬膜外膿瘍・インプラント感染の一例
    水木真平, 官澤洋平, 世戸博之, 石丸直人, 木南佐織
    2018年, 日本プライマリ・ケア連合学会学術大会抄録集, 9th

  • 頸部リンパ節腫脹と紅斑を契機に診断し子宮頸癌を合併した口腔咽頭梅毒の1例
    石丸直人, 官澤洋平, 世戸博之, 木南佐織
    2018年, 日本プライマリ・ケア連合学会学術大会抄録集, 9th

■ 書籍等出版物
  • 治療 CHIRYO 2026年8月号【第1特集】感染症のillness scriptと治療メルクマール／【第2特集】ここが知りたい プライマリ・ケアのオピオイド
    分担執筆, 感冒，インフルエンザ，COVID-19, 南山堂, 2026年08月

  • 雑誌「診断と治療」2026年 Vol.114 No.6 どうみる？ 多疾患併存 マルチモビディティへのアプローチ
    官澤洋平
    共著, マルチモビディティの全体像をつかむ マルチモビディティをどう評価するか① よくみられる疾患クラスター・パターン, 株式会社 診断と治療, 2026年07月

  • 日本プライマリ・ケア連合学会 基本研修ハンドブック 改訂4版
    日本プライマリ・ケア連合学会, 研修ハンドブック編集委員会, 飯塚玄明, 松村真司, 小曽根早知子, 村山愛, 官澤洋平, 矢吹拓, 中山明子, 山梨啓友, 深瀬龍, 横田雄也
    共編者(共編著者), 多疾患併存, 南山堂, 2026年06月

  • 治療 CHIRYO 2026年3月号【第1特集】教科書通りにいかない心不全診療／【第2特集】事例で学ぶ! レセプト返戻・査定の知識
    齋藤秀輝/遠井敬大
    分担執筆, ガイドラインを“ 活かす ”地域心不全診療 ─単なる遵守ではなく，現場で応用する視点─, 南山堂, 2026年03月

  • 2026年03月, 厚生労働省 医療の効率化に向けた領域別タスクシフト推進事業 ( 令和 7 年 3 月公募 )

  • 病みの軌跡を意識した 患者に寄り添う心不全診療 －薬物療法・非薬物療法から緩和療法・ACPまで－
    官澤洋平, 齋藤秀輝
    編者(編著者), 金芳堂, 2025年12月, 日本語, ISBN: 9784765320726

  • 治療 CHIRYO 7月号【第1特集】「治療」presents 総合診療を語り明かす／【第2特集】市販薬のオーバードーズ
    治療編集委員
    分担執筆, Talk 官澤洋平×折茂圭介 専門医取得後の医師のキャリア 医師のライフワークバランス 総合診療は今どこにいて，どこへ向かうのか, 南山堂, 2025年07月

  • レジデントノート 2025年6月号 Vol.27 No.4 誰も教えてくれなかった病棟回診 各時間帯でみるべきもの、やるべきこと、情報収集の勘所
    官澤洋平
    編者(編著者), 羊土社, 2025年05月, ISBN: 9784758127349

  • 老年医学のトビラ
    山田, 悠史, 原田, 洸 (内科医), 坂井, 智達, 内田, 直樹, 榎本 貴一, 吉野, 鉄大, 百武, 美沙, 北澤, 耕司, 前田, 陽平, 官澤 洋平, 柏木, 秀行, 植村, 健司
    分担執筆, 第11章 「食べられない」, メディカルサイエンスインターナショナル, 2025年04月, 日本語, ISBN: 9784815731328

  • 治療 CHIRYO 2025年2月号【第1特集】診療所救急 かかりつけ患者の症状，どこまで診る？／【第2特集】令和の育児観と家族志向のケア
    坂本壮, 宮本侑達
    分担執筆, 動悸 ─すぐに診断がつかないときの心構え─, 2025年02月

  • 総合診療 2024年10月号 特集 化かしが得意なカメレオンな疾患を捕まえろ！ よくある騙され方のゲシュタルト
    佐藤直行
    ④感染性心内膜炎, 2024年10月

  • medicina 2024年10月号 特集 続・Quality Indicatorの実装とその改善 日々の診療に役立つ診療評価指標
    小坂鎮太郎
    分担執筆, 心房細動（AF）の評価指標, 狭心症（胸痛）の評価指標, 2024年10月

  • 治療(CHIRYO)2024年106巻3月号 実際どうなの? SGLT2阻害薬
    官澤洋平
    編者(編著者), 南山堂, 2024年03月, ISBN: 9784525930028

  • がん・非がん患者の呼吸器症状を診る
    官澤, 洋平, 松田, 能宣, 吉松, 由貴, 柏木, 秀行, 森田, 達也
    南江堂, 2023年07月, 日本語, ISBN: 9784524232741

  • 入院患者管理パーフェクト : 病棟診療の勘所 : 受け持ちのその日から退院までフォローする36項目
    石丸, 裕康, 官澤, 洋平
    羊土社, 2023年06月, 日本語, ISBN: 9784758116992

  • medicina 2023年5月号 特集 Common diseaseの処方箋ファイル 臨床経過から学ぶ20症例
    分担執筆, CASE 3 慢性心不全──高血圧症，脂質異常症の既往のある，糖尿病の既往のない65歳男性, 医学書院, 2023年05月

  • meidinca 2023年2月号 特集 慢性疾患診療のお悩みポイントまとめました 高血圧からヘルスメンテナンスまで
    長野 広之
    分担執筆, 慢性心不全の増悪を防ぐにはどうすればいいですか？, 医学書院, 2023年02月

  • medicina 2022年10月号（増大号） 特集 これからもスタンダード！ Quality Indicatorの診療への実装 生活習慣病を中心に
    小坂鎮太郎
    分担執筆, 肺がんの予防と検診の臨床評価指標, 医学書院, 2022年10月

  • 総合診療 2022年8月号 特集 こんなところも！“ちょいあて”エコー POCUSお役立ちTips！ ISSN 2188-8051 定価 2,750円 （本体2,500円+税）
    佐藤直行
    分担執筆, ⑧皮膚軟部感染症×エコー 蜂窩織炎と膿瘍、壊死性筋膜炎, 医学書院, 2022年08月

  • medicina 2022年7月号 特集 日常診療に潜む臨床検査のピットフォールを回避せよ
    鋪野 紀好
    分担執筆, Case 14．コルチゾール正常だから副腎機能は大丈夫！？, 医学書院, 2022年07月

  • エキスパートナース 37巻9号 （2021年7月発行） 特集 よく出会うマルチモビディティ多疾患併存患者をどうみてケアする?
    官澤洋平
    単著, (Part2)(事例1) 比較的よくみかける状態, 照林社, 2021年07月

■ 講演・口頭発表等
  • 多疾患併存マネジメント ワーキンググループ〜アンケート調査について〜
    官澤洋平
    第123回日本内科学会講演会 シンポジウム 内科医による「多疾患併存診療虎の巻」, 2026年04月
    公開講演，セミナー，チュートリアル，講習，講義等

  • In the Clinic クリニカルボトムラインレクチャー(Lecture with Clinical Bottom Line in the "In The Clinic")
    水木 真平, 官澤 洋平, 吉野 鉄大, 河野 圭
    ACP(米国内科学会)日本支部年次総会プログラム集, 2024年06月, 日本語, (一社)米国内科学会日本支部

■ 学術貢献活動
  • In The Clinic翻訳プロジェクト
    米国内科学会日本支部
    学会・研究会等

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