Research activity information

• Dec. 2023 ACNS Red River Bootcamp, ACNS Red River Best Teacher award, Bypass Surgery in Vascular Neurosurgery: Fundamentals and Clinical Applications


• Jul. 2023 第37回日本脳神経外科国際学会フォーラム, Sammy’s Award (2位）


• Nov. 2021 第34回日本脳神経外科同時通訳夏期研修会, Ken’s Award


• Nov. 2021 第34回日本脳神経外科同時通訳夏期研修会, 会長賞


• 2009 神戸大学脳神経外科同門会学術奨励賞, 神戸大学脳神経外科同門会学術奨励賞 (臨床活動部門)

• A morphological features-based nomogram for predicting facial nerve function in the immediate postoperative period after vestibular schwannoma surgery.

  Yuichi Fujita, Yoichi Uozumi, Yosuke Fujimoto, Hiroaki Nagashima, Masaaki Kohta, Kazuhiro Tanaka, Hidehito Kimura, Atsushi Fujita, Eiji Kohmura, Takashi Sasayama

  PURPOSE: Tumor morphology critically influences facial nerve (FN) outcomes following vestibular schwannoma (VS) surgery. This study aimed to develop a nomogram based on preoperative features for preoperative prediction of FN outcomes after VS surgery. METHODS: A retrospective analysis included patients with sporadic VS who underwent surgical resection via the retrosigmoid approach. Tumor size was assessed using the Koos grade, the intrameatal components using the fundal fluid cap (FFC) sign, and the cerebellopontine angle cisternal components using our modified morphological subclassification. Logistic regression analysis was performed to construct a nomogram for predicting immediate postoperative FN function. RESULTS: A total of 265 patients with VS met the inclusion criteria. Of these patients, 62 (23.4%) had poor FN function (House-Brackmann grade ≥ III) immediately after surgery. Univariate logistic regression analysis identified the Koos grade (p = 0.001), FFC sign (p = 0.023), and morphological subtype (p < 0.001) as significant predictors of poor FN function immediately after surgery. In multivariate logistic regression analysis, the FFC sign (OR 2.07, p = 0.042) and morphological subtype (OR 8.21, p < 0.001) remained statistically significant independent predictors of poor FN function. A nomogram constructed based on these indicators demonstrated good discrimination in the training cohort (area under the curve [AUC] 0.80), internal validation cohort (AUC 0.79), and external validation cohort (AUC 0.97). CONCLUSIONS: A simple and reliable nomogram incorporating the Koos grade, FFC sign, and morphological subtype accurately predicts the risk of FN injury during surgery aimed at total resection of VS. This clinically straightforward tool can assist in patient counseling and development of more individualized surgical strategies to improve FN outcomes in patients with VS.

  Mar. 2025, Journal of neuro-oncology, English, International magazine

  Scientific journal


• 硬膜外内頸動脈瘤のFlow diverter留置後の遅発性破裂に関する自験例を含む系統的レビュー

  池内 佑介, 藤田 敦史, 甲田 将章, 中村 直人, 庄瀬 裕康, 木村 英仁, 篠山 隆司

  (一社)日本脳神経血管内治療学会, Nov. 2024, 日本脳神経血管内治療学会学術集会抄録集, 40回, 763 - 763, Japanese


• Efficacy of Surgical Reconstruction With Rectus Abdominis Flap Following en Bloc Resection of the Orbital Contents for Malignant Lacrimal Gland Cancer: A Case Series.

  Misato Ueda, Hirotaka Shinomiya, Ken-Ichi Nibu, Hidehito Kimura, Tadashi Nomura

  In cases of lacrimal gland carcinoma requiring surgical excision of the orbital contents, skull base, and surrounding bones, definitive blockage of the cranial cavity and reconstruction of the anterior skull base with irradiation-acceptable tissue (for possible subsequent radiotherapy) is necessary. However, considerations for quality of life, including cosmetic aspects, such as artificial eye placement and contour morphology, make reconstruction challenging. In three cases of advanced lacrimal gland carcinoma, we performed a reconstruction surgery following an en bloc resection of the orbital contents and lateral orbital bones. A rectus abdominis flap was used, considering both function and morphology. This flap, characterized by reliable anatomical structure and good blood flow, adequately filled the three-dimensional dead space. In our case, the flap fully survived, and no complications such as cerebrospinal fluid leakage or meningitis were observed. Six months after surgery, the flap volume was 31.7-73.3% of its initial size. Considering potential flap shrinkage in the future, it was deemed beneficial to use a slightly excessive volume.

  Sep. 2024, Cureus, 16(9) (9), e69310, English, International magazine

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Predicting impaired cerebrovascular reactivity and risk of hyperperfusion syndrome in carotid artery stenosis using BeamSAT magnetic resonance imaging.

  Yusuke Ikeuchi, Masaaki Kohta, Shunsuke Yamashita, Shunsuke Yamanishi, Yoji Yamaguchi, Jun Tanaka, Kazuhiro Tanaka, Hidehito Kimura, Atsushi Fujita, Kohkichi Hosoda, Eiji Kohmura, Takashi Sasayama

  Pencil-beam presaturation (BeamSAT) magnetic resonance imaging (MRI) produces selective magnetic resonance angiography (MRA) images of specific arteries, including the unilateral internal carotid artery (ICA-selective MRA) or vertebral artery (VA-selective MRA). We evaluate the influence of flow pattern, visualized using BeamSAT MRI, on preoperative cerebral hemodynamic status and postoperative hyperperfusion syndrome (HPS). Patients undergoing carotid artery stenting or carotid endarterectomy were categorized into two groups to evaluate flow pattern. Patients with neither crossflow on BeamSAT MRI nor mismatch in middle cerebral artery (MCA) signal intensity between ICA-selective and conventional MRA were classified into Group I, comprising 29 patients. Group II included all other patients comprising 19 patients, who were suspected of experiencing changes in intracranial flow patterns. Cerebral blood flow and cerebrovascular reactivity (CVR) were assessed using single-photon emission computed tomography, and potential HPS symptoms were retrospectively assessed by chart review. Preoperative ipsilateral CVR was significantly lower in Group II than in Group I (18.0% ± 20.0% vs. 48.3% ± 19.5%; P < 0.0001). Group II showed significantly impaired CVR (odds ratio 17.7, 95% confidence interval 1.82-171; P = 0.013) in multivariate analysis. The partial areas under the curve of the BeamSAT logistic model (0.843) were significantly larger than those of the conventional logistic model (0.626) over the range of high sensitivity (0.6-1) (P = 0.04). The incidence of postoperative HPS symptoms was significantly higher in Group II than in Group I (8/19 vs. 1/29; P = 0.001). BeamSAT MRI may be a valuable and non-invasive tool for assessing cerebral hemodynamics and predicting postoperative HPS.

  Aug. 2024, Journal of the neurological sciences, 463, 123114 - 123114, English, International magazine

  Scientific journal


• Acute morphological changes of impending rupture of vertebral artery dissection: clinical management of symptomatic but unruptured vertebral artery dissection. Illustrative case.

  Tatsuya Mori, Atsushi Fujita, Masaki Iwakura, Jun Imura, Kana Onobuchi, Masaaki Kohta, Hidehito Kimura, Takashi Sasayama

  BACKGROUND: The reported actual risk of rupture for vertebral artery dissection (VAD) in patients presenting with headache is very low, ranging from 0.4% to 1.0%. The authors report a case in which the dissection site dilated rapidly within several hours after the dissection occurred resulting in subarachnoid hemorrhage (SAH). OBSERVATIONS: A 49-year-old healthy man who had participated in a marathon noticed a headache while running. Magnetic resonance imaging (MRI) performed 2 days later revealed no findings suspicious for right VAD, but a string sign was observed in the left side, suggesting left VAD. Three hours following MRI, he developed severe headaches and became unconscious at home, prompting emergency services to rush him to the hospital. A computed tomography scan showed diffuse SAH and a rapidly enlarged aneurysmal dilatation in the right vertebral artery. He underwent endovascular internal trapping to prevent rebleeding. He was discharged without any neurological symptoms. No recurrence or new dissection occurred after 2 years of follow-up. LESSONS: Even in the absence of typical imaging findings, strict management, such as blood pressure control, is required when clinical findings strongly suggest VAD, and differentiation of VAD from primary headache is important. https://thejns.org/doi/10.3171/CASE24202.

  Jul. 2024, Journal of neurosurgery. Case lessons, 8(3) (3), English, International magazine

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• A vertebrobasilar junction aneurysm successfully treated with a combination of surgical clipping and flow diverter placement based on the results of computational fluid dynamics analysis: illustrative case

  Tatsuya Mori, Hidehito Kimura, Atsushi Fujita, Kosuke Hayashi, Tatsuo Hori, Masahiro Sugihara, Yusuke Ikeuchi, Masaaki Kohta, Akio Tomiyama, Takashi Sasayama

  BACKGROUND The treatment of vertebrobasilar junction (VBJ) aneurysms is challenging. Although flow diverters (FDs) are a possible treatment option, geometrical conditions hinder intervention. VBJ aneurysms possess dual inflow vessels from the bilateral vertebral arteries (VAs), one of which is ideally occluded prior to FD treatment. However, it remains unclear which VA should be occluded. OBSERVATIONS A 75-year-old male with a growing VBJ complex aneurysm exhibiting invagination toward the brainstem and causing perifocal edema required intervention. Preoperative computational fluid dynamics (CFD) analysis demonstrated that left VA occlusion would result in more stagnant flow and less impingement of flow than right VA occlusion. According to the simulated strategy, surgical clipping of the left VA just proximal to the aneurysm was performed, followed by FD placement from the basilar artery trunk to the right VA. The patient demonstrated tolerance of the VA occlusion, and follow-up computed tomography angiography at 18 months after FD treatment confirmed the disappearance of the aneurysm. LESSONS Preoperative flow dynamics simulations using CFD analysis can reveal an optimal treatment strategy involving a hybrid surgery that combines FD placement and direct surgical occlusion for a VBJ complex aneurysm.

  Journal of Neurosurgery Publishing Group (JNSPG), Mar. 2024, Journal of Neurosurgery: Case Lessons, 7(10) (10)

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Expression of EGFR and p16 in Squamous Cell Carcinoma of External Auditory Canal.

  Yasuyuki Kajimoto, Hirotaka Shinomiya, Natsumi Uehara, Masanori Teshima, Takeshi Fujita, Akinobu Kakigi, Yoshinori Imamura, Naomi Kiyota, Daisuke Miyawaki, Ryohei Sasaki, Hidehito Kimura, Ken-Ichi Nibu

  The expression of EGFR and p16 in the external auditory canal squamous cell carcinoma (EACSCC) and their impacts on oncological outcomes were not well studied. Seventeen-one consecutive patients who were treated for EACSCC at Kobe University Hospital from 1995 to 2018 were enrolled in this study. The expression of EGFR, and p16 were evaluated and their impacts on oncological outcomes were statistically analyzed. Positive expression of EGFR was observed in 62 patients (87%). Strong positive expression of p16 were observed in 18 patients (32.4%), and weakly positive expression in 30 patients (42.3%), respectively. While the number of the patients with negative EGFR expression were limited, all the surgically treated patients with negative EGFR expression have been alive without disease. In the patients with T3 & T4a EACSCC, prognosis of the patients with positive p16 expression EACSCC tended to be better than those with negative p16 expression. These results suggest the clinical significance of EGFR and p16 expressions in the patients with advanced EACSCC to predict oncological outcomes.

  Jan. 2024, The Kobe journal of medical sciences, 69(4) (4), E144-E150, English, Domestic magazine

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Incidence and Outcomes of Aneurysmal Subarachnoid Hemorrhage: A Multicenter Retrospective Registry-based Descriptive Trial in Kobe City.

  Tsuyoshi Ohta, Shirabe Matsumoto, Ryu Fukumitsu, Hirotoshi Imamura, Hidemitsu Adachi, Yoshie Hara, Kohkichi Hosoda, Hidehito Kimura, Kazuyuki Kuwayama, Takashi Mizowaki, Yasuhiko Motooka, Shiro Miyata, Narihide Shinoda, Yasushi Ueno, Ikuya Yamaura, Yasuhisa Yoshida, Chiaki Sakai, Nobuyuki Sakai

  The current study aims to evaluate the incidence and results of aneurysmal subarachnoid hemorrhage (aSAH) throughout Kobe City. Based on a multicenter retrospective registry-based descriptive trial involving all 13 primary stroke centers in Kobe City, patients with aSAH treated between October 2017 and September 2019 were studied. A total of 334 patients were included, with an estimated age-adjusted incidence of 11.12 per 100,000 person-years. Curative treatment was given to 94% of patients, with endovascular treatment (51%) preferred over surgical treatment (43%). Of the patients, 12% were treated by shunt surgery for sequential hydrocephalus with a worse outcome at 30 days or discharge (14% vs. 46%, odds ratio (OR): 0.19, 95% confidence interval (CI): 0.088-0.39, p-value <0.001). As for vasospasm and delayed cerebral ischemia, most patients were given intravenous fasudil infusion (73%), with endovascular treatment for vasospasm in 24 cases (7.2%). The fasudil group had more good outcomes (42% vs. 30%, OR: 1.64, 95% CI: 0.95-2.87, p-value = 0.075) and significantly less death (3.3% vs. 35%, OR: 0.064, 95% CI: 0.024-0.15, p-value <0.001) at 30 days or discharge. Mortality rose from 12% at 30 days or discharge to 17% at 1 year, but neurological function distribution improved over time (modified Rankin Scale 0-2 was 39% at 30 days or discharge, 53% at 60 days, and 63% at 1 year). Our retrospective registered trial presented various statistics on aSAH, summarizing the current treatment status and prognosis.

  Aug. 2023, Neurologia medico-chirurgica, English, Domestic magazine

  Scientific journal


• Combined transarterial and transvenous embolization of anterior cranial fossa dural arteriovenous fistula.

  Masahiro Sugihara, Atsushi Fujita, Yusuke Ikeuchi, Tatsuo Hori, Masaaki Kohta, Kazuhiro Tanaka, Hidehito Kimura, Takashi Sasayama

  BACKGROUND: Excessive glue injection into the drainage vein in patients with dural arteriovenous fistula (dAVF) can result in venous obstruction. We performed transarterial embolization (TAE) combined with transvenous embolization (TVE) with coils to prevent the glue from migrating into the normal cortical veins. CASE DESCRIPTION: A 57-year-old man was pointed out to have a Borden Type III anterior cranial fossa dAVF during a check-up for putaminal hemorrhage. Because a left frontal normal cortical vein drained into the pathological drainage vein, excessive glue injection into the drainage vein may have caused venous obstruction. We performed TVE with coils at the foot of the draining vein to prevent excessive migration of glue into the drainer, followed by TAE with glue. With this technique, complete obliteration of the shunt without venous ischemia was obtained. CONCLUSION: The combined treatment of TAE and TVE is effective in preventing venous ischemia caused by unintended migration of glue cast into the drainage vein.

  2023, Surgical neurology international, 14, 277 - 277, English, International magazine

  Link to Kobe Univ. Repository (Kernel)


• 髄液胎盤型アルカリフォスファターゼ測定が診断に有用だった脊髄再発germinomaの一例

  田中 智子, 刀坂 公崇, 十河 正弥, 千原 典夫, 上田 健博, 関口 兼司, 木村 英仁, 児玉 良典, 篠山 隆司, 松本 理器

  (一社)日本神経学会, Nov. 2022, 臨床神経学, 62(11) (11), 896 - 896, Japanese


• 髄液胎盤型アルカリフォスファターゼ測定が診断に有用だった脊髄再発germinomaの一例

  田中 智子, 刀坂 公崇, 十河 正弥, 千原 典夫, 上田 健博, 関口 兼司, 木村 英仁, 児玉 良典, 篠山 隆司, 松本 理器

  (一社)日本神経学会, Nov. 2022, 臨床神経学, 62(11) (11), 896 - 896, Japanese


• The impact of hormonal dynamics and serum sodium fluctuations on symptomatic vasospasm after subarachnoid hemorrhage.

  Tomoaki Harada, Yoichi Uozumi, Hidenori Fukuoka, Shigeru Miyake, Daisuke Yamamoto, Yusuke Okamura, Taiji Ishii, Shotaro Tatsumi, Takashi Mizobe, Hideo Aihara, Kazuhiro Tanaka, Eiji Kohmura, Takashi Sasayama

  BACKGROUND: Symptomatic vasospasm (SVS) is a major cause of morbidity and mortality in aneurysmal subarachnoid hemorrhage (SAH), and serum sodium frequently decreases before SVS. Serum sodium changes might be regulated by sodium metabolism-related hormones. This multi-institutional prospective cohort study therefore investigated the measurement of sodium metabolism-related hormones to elucidate the pathophysiology of serum sodium changes in SAH. METHODS: SAH patients were treated with clipping or coiling from September 2017 to August 2020 at five hospitals. The laboratory data of 133 SAH patients were collected over 14 days and correlations between changes in serum sodium, sodium metabolism-related hormones (plasma adrenocorticotropic hormone (ACTH), serum cortisol, plasma arginine vasopressin (AVP)), and SVS were determined. Serum sodium concentrations were measured every day and serum sodium levels >135 mEq/L were maintained until day 14. RESULTS: Of the 133 patients, 18 developed SVS within 14 days of subarachnoid hemorrhage onset (SVS group) and 115 did not suffer from SVS (non-SVS group). Circulating AVP, ACTH, and cortisol concentrations were significantly higher on day 1 in the SVS group compared with the non-SVS group. Fluctuations in serum sodium in the SVS group were significantly higher than those in the non-SVS group. There were antiparallel fluctuations in serum sodium and potassium from days 2 to 14. CONCLUSIONS: Elevated levels of ACTH/cortisol and AVP on day 1 may be predictive markers for the occurrence of SVS. Multiple logistic regression analysis showed that serum sodium fluctuations were associated with SVS occurrence. Serum sodium fluctuations were associated with stress-related hormonal dynamics. (249 words).

  Sep. 2022, Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 103, 131 - 140, English, International magazine

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Absence of the Anterior Communicating Artery on Selective MRA is Associated with New Ischemic Lesions on MRI after Carotid Revascularization.

  S Yamashita, M Kohta, K Hosoda, J Tanaka, K Matsuo, H Kimura, K Tanaka, A Fujita, T Sasayama

  BACKGROUND AND PURPOSE: ICA-selective MRA using a pencil beam presaturation pulse can accurately visualize anterior communicating artery flow. We evaluated the impact of anterior communicating artery flow on the perioperative hemodynamic status and new ischemic lesions after carotid revascularization. MATERIALS AND METHODS: Eighty-three patients with carotid artery stenosis were included. We assessed anterior communicating artery flow using ICA-selective MRA. The preoperative hemodynamic status was measured using SPECT. We also measured the change in regional cerebral oxygen saturation after temporary ICA occlusion. New ischemic lesions were evaluated by DWI on the day after treatment. RESULTS: Anterior communicating artery flow was detected in 61 patients, but it was not detected in 22 patients. Preoperative cerebrovascular reactivity was significantly higher in patients with (versus without) anterior communicating artery flow with a mean peak systolic velocity of ≥200 cm/s (39.6% [SD, 23.8%] versus 25.2% [SD, 16.4%]; P = .030). The decrease in mean regional cerebral oxygen saturation was significantly greater in patients without (versus with) anterior communicating artery flow (8.5% [SD, 5.6%] versus 3.7% [SD, 3.8%]; P = .002). New ischemic lesions after the procedure were observed in 23 patients. The multivariate logistic regression analysis revealed that anterior communicating artery flow (OR, 0.07; 95% CI, 0.012-0.45; P = .005) was associated with new ischemic lesions. CONCLUSIONS: The absence of anterior communicating artery flow influenced the perioperative hemodynamic status in patients with carotid stenosis and was associated with an increased incidence of new ischemic lesions after carotid revascularization.

  Aug. 2022, AJNR. American journal of neuroradiology, 43(8) (8), 1124 - 1130, English, International magazine

  Scientific journal


• Lattice Boltzmann method for multiphase and multicomponent flows: A review

  Seta, Takeshi, Yamamoto, Keiichi, Yoshino, Masato, Takada, Naoki, Matsukuma, Yosuke, Yamamoto, Kazuhiro, Hayashi, Kosuke, Kimura, Hidehito, Tomiyama, Akio

  Abstract : The authors present the development of the lattice Boltzmann method (LBM) for application to gas-liquid flows, gas mixture, and gas-solid flows. The LBM scheme is constructed using a simple procedure that takes into account collision and propagation processes. The fluid density is calculated using the sum of the distribution function with respect to number of the discrete velocity. Since all distribution functions exist in the computational region with adequate boundary conditions, the LBM is effective for mass conservation and can be adjusted to the multiphase flow simulation. For the multiphase flow simulation, the color-gradient model is first proposed, and then the Shan-Chen and free energy models were implemented using the LBM. Then, the phase-field model, which is commonly used in LBMs, was investigated. The phase-field method easily captures the complicated interface and calculates multiphase flows with high density and viscosity ratios. For multicomponent flows, the LBM can calculate the Stefan--Maxwell equation. The present model calculates multicomponent phenomena, including uphill diffusion, without interpolating the distribution function. For particulate flows, we list the momentum exchange method and the immersed boundary -lattice Boltzmann method (IB-LBM) and explain the occurrence of boundary slip. Finally, we introduce models for wettability, including three phases: gas, liquid, and solid. Keywords : Lattice Boltzmann method, Multiphase flow, Multicomponent flow, Particulate flow, Wettability Cite this article : Seta, T.; Yamamoto, K.; Yoshino, M.; Takada, N.; Matsukuma, Y.; Yamamoto, K.; Hayashi, K.; Kimura, H.; Tomiyama, A. Lattice Boltzmann method for multiphase and multicomponent flows: A review. Muitiph. Sci. Technol. 2022, Vol. 34, in press. https://doi.org/10.1615/MultScienTechn.2022044039

  Begell House, Jul. 2022, Multiphase Science and Technology, 34, in press., English, International magazine

  [Refereed]

  Scientific journal


• Unilateral approach for bilateral middle cerebral artery aneurysms assisted by preoperative understandings of aneurysm wall properties:2-dimensional operative video.

  Hidehito Kimura, Kosuke Hayashi, Susumu Osaki, Ayaka Shibano, Yuichi Fujita, Hiroaki Nagashima, Akio Tomiyama, Takashi Sasayama

  Mar. 2022, World neurosurgery, English, International magazine

  Link to Kobe Univ. Repository (Kernel)


• Efficacy of a High-definition Three-dimensional Exoscope in Simultaneous Transcranial and Endoscopic Endonasal Surgery: A Case Report.

  Ayaka Shibano, Hidehito Kimura, Shun Tatehara, Tatsuya Furukawa, Kazuki Inoue, Yuichi Fujita, Hiroaki Nagashima, Shunsuke Yamanishi, Tadashi Nomura, Ken-Ichi Nibu, Takashi Sasayama

  Owing to recent advances in medical optical technology, a high-definition (4K) three-dimensional (3D) exoscope has been developed as an alternative tool to using conventional microscopes for microscopic surgery, and its efficacy for neurosurgery has been reported. We report a case who underwent simultaneous surgery aiming for en bloc resection of an anterior skull base malignancy with concurrent exoscopic transcranial and endoscopic endonasal approaches using a 4K 3D exoscope. The patient was a 76-year-old woman who underwent en bloc resection for an anterior skull base olfactory neuroblastoma 13 years ago. After confirming the recurrence of progressive olfactory neuroblastoma, tumor resection was again decided to be performed. As with the first procedure, surgery was performed in an en bloc manner, using both transcranial and endonasal approaches. Exoscope provided enough space above the surgical field to allow us to perform transcranial and endonasal surgeries simultaneously. Moreover, the surgeons could maintain a comfortable posture throughout the procedure, and total tumor removal was successfully achieved without any abnormal event. To our knowledge, this is the first report of the introduction of an exoscope aiming for en bloc resection of an anterior skull base malignancy while performing simultaneous surgery with both transcranial and endonasal approaches. We believe that the more cases are accumulated, the more efficacy of a 4K 3D exoscope will be elucidated.

  2022, NMC case report journal, 9, 243 - 247, English, Domestic magazine

  Link to Kobe Univ. Repository (Kernel)


• Roles of skull base surgery and particle radiotherapy for orbital malignant tumors involving the skull base.

  Masanori Teshima, Hirotaka Shinomiya, Hidehito Kimura, Kazunobu Hashikawa, Naomi Kiyota, Daisuke Miyawaki, Ryohei Sasaki, Eiji Kohmura, Ken-Ichi Nibu

  Purpose: To investigate the oncological outcomes of orbital malignant tumors invading the skull base. Methods: A retrospective analysis was conducted on 16 patients with orbital malignant tumors invading the skull base. Eleven patients were treated with skull base surgery, four patients were treated with particle therapies, and one patient was treated with chemoradiotherapy (CRT) as initial treatment. Results: The most frequent histological type was adenoid cystic carcinoma in seven patients, followed by squamous cell carcinoma in two patients. Local recurrence occurred in two of the six surgically treated patients who did not receive postoperative radiotherapy (RT) or CRT. One of them was successfully salvaged by RT, and the other died of disease. With a median follow-up of 24 months, the 2-year overall, local control, and disease-free survival rates of all patients were 82.5%, 87.5%, and 59%, respectively. Conclusions: Patients with positive surgical margins were at risk of local recurrence. Postoperative RT should be considered for all surgically treated patients.Level of Evidence: 4.

  Dec. 2021, Laryngoscope investigative otolaryngology, 6(6) (6), 1347 - 1352, English, International magazine

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• 内頸動脈狭窄症におけるBeam SAT MRAによる周術期脳血流循環動態評価

  山下 俊輔, 甲田 将章, 田中 潤, 細田 弘吉, 木村 英仁, 藤田 敦史, 篠山 隆司

  (一社)日本脳循環代謝学会, Nov. 2021, 脳循環代謝, 33(1) (1), 104 - 104, Japanese


• Numerical Simulations of Flows in a Cerebral Aneurysm Using the Lattice Boltzmann Method with the Half-Way and Interpolated Bounce-Back Schemes

  Susumu Osaki, Kosuke Hayashi, Hidehito Kimura, Takeshi Seta, Takashi Sasayama, Akio Tomiyama

  Lattice Boltzmann simulations and a velocity measurement of flows in a cerebral aneurysm reconstructed from MRA (magnetic resonance angiography) images of an actual aneurysm were carried out and the numerical results obtained using the bounce-back schemes were compared with the experimental data to discuss the effects of the numerical treatment of the no-slip boundary condition of the complex boundary shape of the aneurysm on the predictions. The conclusions obtained are as follows: (1) measured data of the velocity in the aneurysm model useful for validation of numerical methods were obtained, (2) the numerical stability of the quadratic interpolated bounce-back scheme (QBB) in the flow simulation of the cerebral aneurysm is lower than those of the half-way bounce-back (HBB) and the linearly interpolated bounce-back (LBB) schemes, (3) the flow structures predicted using HBB and LBB are comparable and agree well with the experimental data, and (4) the fluctuations of the wall shear stress (WSS), i.e., the oscillatory shear index (OSI), can be well predicted even with the jaggy wall representation of HBB, whereas the magnitude of WSS predicted with HBB tends to be smaller than that with LBB.

  MDPI AG, Sep. 2021, Fluids, 6(10) (10), 338 - 338

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Newly Identified Hemodynamic Parameter to Predict Thin-Walled Regions of Unruptured Cerebral Aneurysms Using Computational Fluid Dynamics Analysis.

  Hidehito Kimura, Susumu Osaki, Kosuke Hayashi, Masaaki Taniguchi, Yuichi Fujita, Takeshi Seta, Akio Tomiyama, Takashi Sasayama, Eiji Kohmura

  BACKGROUND: The thin-walled regions (TIWRs) of intracranial aneurysms have a high risk of rupture during surgical manipulation. They have been reported to be predicted by wall shear stress and pressure (PS) based on computational fluid dynamics analysis, although this remains controversial. In this study, we investigated whether the oscillatory shear index (OSI) can predict TIWRs. METHODS: Twenty-five unruptured aneurysms were retrospectively analyzed; the position and orientation of the computational fluid dynamics color maps were adjusted to match the intraoperative micrographs. The red area on the aneurysm wall was defined as TIWR, and if most of the regions on the color map corresponding to TIWR were OSI low (lower quartile range), time-averaged wall shear stress (TAWSS) high, or PS high (upper quartile range), each region was defined as a matched region and divided by the total number of TIWRs to calculate the match rate. In addition, the mean values of OSI, TAWSS, and PS corresponding to TIWRs were quantitatively compared with those in adjacent thick-walled regions. RESULTS: Among 27 TIWRs of 25 aneurysms, 23, 10, and 14 regions had low OSI, high TAWSS, and high PS regions (match rate: 85.2%, 37.0%, and 51.9%), respectively. Receiver operating characteristic curve analysis demonstrated that OSI was the most effective hemodynamic parameter (area under the curve, 0.881), followed by TAWSS (0.798). Multivariate analysis showed that OSI was a significant independent predictor of TIWRs (odds ratio, 18.30 [95% CI, 3.2800-102.00], P < 0.001). CONCLUSIONS: OSI may be a unique predictor for TIWRs. Low OSI strongly corresponds with TIWRs of intracranial aneurysms.

  Aug. 2021, World neurosurgery, 152, e377-e386, English, International magazine

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Potential of machine learning to predict early ischemic events after carotid endarterectomy or stenting: a comparison with surgeon predictions

  Kazuya Matsuo, Atsushi Fujita, Kohkichi Hosoda, Jun Tanaka, Taichiro Imahori, Taiji Ishii, Masaaki Kohta, Kazuhiro Tanaka, Yoichi Uozumi, Hidehito Kimura, Takashi Sasayama, Eiji Kohmura

  Springer Science and Business Media LLC, Jun. 2021, Neurosurgical Review

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Anatomical variation of the internal carotid artery and its implication to the endoscopic endonasal translacerum approach.

  Toru Umehara, Masaaki Taniguchi, Nobuyuki Akutsu, Hidehito Kimura, Yoichi Uozumi, Tomoaki Nakai, Haruhiko Kishima, Eiji Kohmura

  BACKGROUND: The endoscopic endonasal trans-lacerum approach (EETLA) is useful in handling skull base tumors around inferior petrous apex (IPA); however, its surgical corridor is exclusively a triangular space (supra-eustachian triangle [SET]), between the internal carotid artery (ICA) and eustachian tube. METHODS: We investigated correlation between SET size and extent of resection around the IPA (lateral extent of resection [EOR]) through a retrospective analysis of 15 surgeries using EETLA. RESULTS: Of 15 cases (9 chordomas, 4 chondrosarcomas, and 2 meningiomas), 20 sides of IPA were affected by the tumor. When being restricted to sides with severe lateral tumor extension beyond the midpoint of petrous ICA (10 sides), the SET size was significantly broader in the group with lateral EOR of ≥90% (p value = 0.019). CONCLUSIONS: The SET size was a powerful index of tumor resectability in EETLA, especially in cases with severe tumor extension. The individual anatomical variations should be considered when determining EETLA application.

  May 2021, Head & neck, 43(5) (5), 1535 - 1544, English, International magazine

  Scientific journal


• New proposal to revise the classification for squamous cell carcinoma of the external auditory canal and middle ear

  H Shinomiya, N Uehara, T Fujita, K Yoshida, Y Imamura, M Teshima, H Kimura, D Miyawaki, A Kakigi, N Kiyota, N Otsuki, R Sasaki, E Kohmura, K Nibu

  The prognosis of patients with advanced squamous cell carcinoma of the external auditory canal and middle ear has been improved by advances in skull base surgery and multidrug chemoradiotherapy during the last two decades. Ninety-five patients with squamous cell carcinoma of the external auditory canal and middle ear who were treated between 1998 and 2017 were enrolled. The number of patients with tumour stages T₁, T₂, T₃ and T₄ was 15, 22, 24 and 34, respectively. Oncological outcomes and prognostic factors were retrospectively investigated. Among patients with T₄ disease, invasion of the brain (p = 0.024), carotid artery (p = 0.049) and/or jugular vein (p = 0.040) were significant predictors of poor prognosis. The five-year overall survival rate of patients with at least one of these factors (T_4b) was significantly lower than that of patients without these factors (T_4a) (25.5 vs 65.5 per cent, p = 0.049). It is proposed that stage T₄ be subclassified into T_4a and T_4b according to the prognostic factors.

  Cambridge University Press (CUP), Apr. 2021, The Journal of Laryngology & Otology, 135(4) (4), 297 - 303

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Acute Occlusion of the Ventriculoperitoneal Shunt Due to Factor XIII Deficiency-related Postoperative Hemorrhage: A Case Report

  Shunsuke YAMANISHI, Hidehito KIMURA, Hideya HAYASHI, Yoji YAMAGUCHI, Yuichi FUJITA, Tomoaki NAKAI, Yoichi UOZUMI, Yoshio KATAYAMA, Masaaki TANIGUCHI, Takashi SASAYAMA

  Japan Neurosurgical Society, 2021, NMC Case Report Journal, 8(1) (1), 573 - 577

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Stroke Systems of Care During the COVID-19 Epidemic in Kobe City.

  Nobuyuki Ohara, Hirotoshi Imamura, Hidemitsu Adachi, Yoshie Hara, Kohkichi Hosoda, Hidehito Kimura, Kazuyuki Kuwayama, Takashi Mizowaki, Yasuhiko Motooka, Kazuya Nakashima, Narihide Shinoda, Takeshi Takamoto, Yasushi Ueno, Ikuya Yamaura, Chie Yanagihara, Yasuhisa Yoshida, Michi Kawamoto, Nobuyuki Sakai

  BACKGROUND: The novel coronavirus disease 2019 (COVID-19) outbreak raised concerns over healthcare systems' ability to provide suitable care to stroke patients. In the present study, we examined the provision of stroke care in Kobe City during the COVID-19 epidemic, where some major stroke centers ceased to provide emergency care. METHODS: This was a cross-sectional study. The Kobe Stroke Network surveyed the number of stroke patients admitted to all primary stroke centers (PSCs) in the city between March 1 and May 23, 2020, and between March 3 and May 25, 2019. In addition, online meetings between all PSC directors were held regularly to share information. The survey items included emergency response system characteristics, number of patients with stroke hospitalized within 7 days of onset, administered treatment types (IV rt-PA, mechanical thrombectomy, surgery, and endovascular therapy), and stroke patients with confirmed COVID-19. RESULTS: During the period of interest in 2020, the number of stroke patients hospitalized across 13 PSCs was 813, which was 15.5% lower than that during the same period of 2019 (p = 0.285). The number of patients admitted with cerebral infarction, intracerebral hemorrhage, and subarachnoid hemorrhage decreased by 15.4% (p = 0.245), 16.1% (p = 0.659), and 14.0% (p = 0.715), respectively. However, the rates of mechanical thrombectomy and surgery for intracerebral hemorrhage were slightly increased by 12.1% (p = 0.754) and 5.0% (p = 0.538), respectively. PSCs that ceased to provide emergency care reported a decrease in the number of stroke cases of 65.7% compared with the same period in 2019, while other PSCs reported an increase of 0.8%. No case of a patient with stroke and confirmed COVID-19 was reported during the study period. CONCLUSION: Kobe City was able to maintain operation of its stroke care systems thanks to close cooperation among all city PSCs and a temporal decrease in the total number of stroke cases.

  Dec. 2020, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 29(12) (12), 105343 - 105343, English, International magazine

  Scientific journal


• [Sellar and Parasellar Inflammatory Lesions with Impaired Visual Function:Clinical Features and Endoscopic Surgical Outcomes of Six Cases].

  Shinichi Miura, Yoichi Uozumi, Masaaki Taniguchi, Tomoaki Nakai, Hidehito Kimura, Eiji Kohmura

  Accurate diagnosis and treatment of sellar and parasellar inflammatory lesions is difficult. We report six patients with sellar and parasellar inflammatory lesions and impaired visual function, who underwent endonasal endoscopic surgery. These patients included one with aspergillosis, one with hypertrophic pachymeningitis, one patient with abscess, and three with idiopathic granulomatous lesions. Following surgery and medication, visual function improved in patients with aspergillosis, hypertrophic pachymeningitis, and abscess. In patients with idiopathic granulomatous inflammation, visual function improved in one out of three patients. The treatment outcome for sellar and parasellar inflammatory lesions with impaired visual function depends on the surgery as well as on the reaction to postoperative medication. In the present study, the functional prognosis of patients with idiopathic granulomatous lesions was relatively poor when compared with that of patients with other inflammatory lesions.

  Oct. 2020, No shinkei geka. Neurological surgery, 48(10) (10), 915 - 920, Japanese, Domestic magazine

  Scientific journal


• 頸動脈狭窄症治療(CEA/CAS)は長期生存に有効か?

  細田 弘吉, 藤田 敦史, 甲田 将章, 田中 潤, 松尾 和哉, 中居 友昭, 石井 大嗣, 木村 英仁, 甲村 英二

  (一社)日本脳卒中の外科学会, Jul. 2020, 脳卒中の外科, 48(4) (4), 275 - 280, Japanese


• En Bloc Subtotal Temporal Bone Resection in a Case of Advanced Ear Cancer: 2-Dimensional Operative Video.

  Hidehito Kimura, Masaaki Taniguchi, Hirotaka Shinomiya, Masanori Teshima, Yuichi Fujita, Kazunobu Hashikawa, Ken-Ichi Nibu, Eiji Kohmura

  Temporal bone cancer is extremely rare; thus, the optimal surgical strategy for advanced tumors, en bloc vs piecemeal resection, remain controversial. Some authors have favored piecemeal resection and reported comparable outcomes.1 Other authors recommend the use of en bloc subtotal temporal bone resection (STBR) for advanced tumors and reported better outcomes, although long-term cancer control remains uncertain.2 Because of the technical difficulty and the lack of demonstrative surgical videos, STBR has not been sufficiently distributed. This video demonstrates en bloc STBR in a stepwise manner with particular focus on the neurosurgeon's role and aims to improve its safety, feasibility, and distribution. This video conforms to the description of Osawa et al3 in the designations for each segment of the petrous ICA. A 67-yr-old man suffered from consistent otorrhea and underwent tympanoplasty at an outside hospital 1 yr earlier. Following a histopathological diagnosis of squamous cell carcinoma in the specimen, he underwent chemoradiotherapy (cisplatin + 70 Gy). However, a current imaging revealed a recurrent tumor and he was admitted to our hospital for radical resection. Computed tomography revealed a disrupted external auditory canal and magnetic resonance imaging indicated a carcinoma equivalent to Pittsburg stage T3. The patient underwent radical STBR without complications. His postoperative course was uneventful. At 2 yr postoperative, his modified Rankin scale score was 1, no recurrence was noted, and his facial nerve function was restored to House-Brackmann Grade IV. This video was reproduced with informed consent from the patient.

  May 2020, Operative neurosurgery (Hagerstown, Md.), English, International magazine

  [Refereed]

  Scientific journal


• Submucosal Inferior Turbinectomy to Widen the Surgical Corridor for Endoscopic Endonasal Skull Base Surgery.

  Yoichi Uozumi, Masaaki Taniguchi, Toru Umehara, Tomoaki Nakai, Hidehito Kimura, Eiji Kohmura

  The nasal cavity is the exclusive surgical corridor for endoscopic endonasal surgery; however, it is sometimes too narrow to allow extensive surgical maneuvering. Here we show the technique of submucosal inferior turbinectomy (SIT) to widen this surgical corridor. Its effectiveness is evaluated quantitatively by comparing pre- and intraoperative magnetic resonance images. Between March 2015 and October 2018, we performed endoscopic endonasal resection of 57 skull base tumors with 3T intraoperative magnetic resonance imaging (iMRI). Among these resections, cases with previous endonasal surgery and cases for which the iMRI did not cover the entire nasal cavity were excluded. Finally, six cases with and 19 cases without SIT were included in the subsequent retrospective analysis. We measured the dimensions of the narrowest area in inferior nasal cavity on pre- and intraoperative coronal plane gadolinium (Gd)-enhanced T1-weighted MR images using dedicated software, and compared them. The incidence rates of postoperative nasal complaints at outpatient clinics were also compared. Considerable widening of the inferior nasal cavity could be achieved with the SIT, which was statistically significant compared with those without the SIT (111.1 ± 56.5% vs. 39.4 ± 59.4%, respectively; P = 0.0093). In terms of the incidence rate of postoperative nasal complaints at 6 months, there was no statistical difference between the groups (33.3% vs. 15.8%, respectively; P = 0.35). SIT is effective for widening the surgical corridor while keeping nasal function and is especially helpful for lower clivus and laterally extended skull base lesions.

  May 2020, Neurologia medico-chirurgica, English, Domestic magazine

  [Refereed]

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Comparative Evaluation of 3-Dimensional High Definition and 2-Dimensional 4-K Ultra-High Definition Endoscopy Systems in Endonasal Skull Base Surgery.

  Yoichi Uozumi, Masaaki Taniguchi, Tomoaki Nakai, Hidehito Kimura, Toru Umehara, Eiji Kohmura

  BACKGROUND: The differences between 3-dimensional (3D) high definition (HD) and 2-dimensional (2D) 4-K ultra-HD (4K) endoscopy and their respective advantages remain unclear. OBJECTIVE: To evaluate the utility of these endoscopy systems in endonasal skull base surgery. METHODS: Consecutive series of endoscopic endonasal surgeries performed after introduction of 3D/HD and 2D/4K systems (July 2017) were retrospectively evaluated. Sporadic cases treated with either system, or a conventional 2D standard definition (SD) system, during the rental period from March 2016 were also included. Objective comparisons between the systems were made for newly diagnosed Knosp grade 0 to 3 pituitary adenomas. Surgical procedures were divided into nasal, sphenoidal, and intradural phases, and the surgical procedural time was compared for each phase. The time required for and accuracy of suturing the sellar floor dura was also evaluated. RESULTS: A total of 74 cases were treated with 3D/HD and/or 2D/4K, and 12 cases with 2D/SD. 3D/HD was advantageous in the nasal phase because of its intuitive depth perception. 2D/4K was advantageous in the intradural phase because of its superior image quality. Surgical time of the nasal phase with 3D/HD, and that of the intradural phase with 2D/4K, were significantly shorter than that with 2D/SD. The time required for and accuracy of sellar floor dural suturing showed a trend toward improving in the order of 2D/SD, 2D/4K, and 3D/HD. CONCLUSION: 3D/HD and 2D/4K endoscopy systems have different advantages, which are useful in distinct surgical phases. Understanding the characteristics of endoscopy systems is important for selecting the most appropriate system for distinct surgical situations.

  Jan. 2020, Operative neurosurgery (Hagerstown, Md.), English, International magazine

  [Refereed]


• Numerical simulations of flows in cerebral aneurysms using the lattice boltzmann method

  Susumu Osaki, Kosuke Hayashi, Hidehito Kimura, Eiji Kohmura, Akio Tomiyama

  American Society of Mechanical Engineers (ASME), 2020, American Society of Mechanical Engineers, Fluids Engineering Division (Publication) FEDSM, 2, English

  International conference proceedings


• DWI for Monitoring the Acute Response of Malignant Gliomas to Photodynamic Therapy

  Y. Fujita, T. Sasayama, K. Tanaka, K. Kyotani, H. Nagashima, M. Kohta, H. Kimura, A. Fujita, E. Kohmura

  BACKGROUND AND PURPOSE: Photodynamic therapy is a novel treatment that provides effective local control, but little is known about photodynamic therapy-induced changes on MR imaging. The aim of this study was to assess the utility of DWI and ADC in monitoring the response of malignant gliomas to photodynamic therapy. MATERIALS AND METHODS: Time-dependent changes in DWI and ADC values after photodynamic therapy were analyzed in a group that received photodynamic therapy in comparison with a group that did not. RESULTS: Twenty-four patients were enrolled (photodynamic therapy, n = 14; non-photodynamic therapy, n = 10). In all patients who received photodynamic therapy, linear high signals on DWI in the irradiated area were detected adjacent to the resection cavity and were 5-7 mm in depth from 1 day posttreatment and disappeared in about 30 days without any neurologic deterioration. The non-photodynamic therapy group did not show this change. The photodynamic therapy group had significantly lower ADC values from 1 day posttreatment (P < .001), which increased steadily and disappeared by 30 days. There was no decline or time-dependent change in ADC values in the non-photodynamic therapy group. CONCLUSIONS: The acute response of malignant gliomas to photodynamic therapy was detected as linear high signals on DWI and as a decrease in ADC values. These findings were asymptomatic and transient. Although the photodynamic therapy-induced acute response on MR imaging disappeared after approximately 30 days, it may be helpful for confirming the photodynamic therapy-irradiated area.

  American Society of Neuroradiology (ASNR), Nov. 2019, American Journal of Neuroradiology, 40(12) (12), 2045 - 2051, English, International magazine

  Scientific journal


• AIの機械学習で頸動脈狭窄症治療後早期の転帰を予測する 実臨床での応用

  松尾 和哉, 藤田 敦史, 細田 弘吉, 田中 潤, 今堀 太一郎, 石井 大嗣, 甲田 将章, 田中 一寛, 魚住 洋一, 木村 英仁, 甲村 英二

  (NPO)日本脳神経血管内治療学会, Nov. 2019, 脳血管内治療, 4(Suppl.) (Suppl.), S212 - S212, Japanese

  [Refereed]


• Pencil Beam Presaturation Magnetic Resonance Imaging Helps to Identify Patients at Risk for Intolerance to Temporary Internal Carotid Artery Occlusion During Carotid Endarterectomy and Carotid Artery Stenting.

  Jun Tanaka, Kohkichi Hosoda, Kazuya Matsuo, Katsusuke Kyotani, Youta Takemoto, Yusuke Yamamoto, Atsushi Fujita, Masaaki Kohta, Hidehito Kimura, Takashi Sasayama, Eiji Kohmura

  BACKGROUND: There has been no effective method to predict ischemic intolerance to temporary internal carotid artery (ICA) occlusion during carotid artery reconstruction. Pencil beam presaturation (BeamSAT) pulse suppresses the flow signal of the target vessel in magnetic resonance angiography (MRA). Applying this method, we constructed ICA-selective MRA images. The aim of this study was to identify patients at risk for ischemic intolerance by ICA-selective MRA. METHODS: By evaluating flow of anterior communicating artery (Acom) and A1 portion of anterior cerebral artery with ICA-selective MRA and posterior communicating artery (Pcom) with conventional MRA, we investigated associations of these collateral flow patterns with ischemic intolerance and decrease of regional cerebral oxygen saturation. RESULTS: The study included 58 patients who underwent carotid endarterectomy or carotid artery stenting. Six of 7 patients without Acom flow and Pcom flow demonstrated ischemic intolerance, whereas all patients (n = 51) with Acom and/or Pcom flow demonstrated tolerance. The accuracy of this prediction model according to Acom and Pcom flow patterns for ischemic intolerance was 0.98 (P = 0.01, binomial test). Regional cerebral oxygen saturation decrease after ICA occlusion was significantly larger in patients without Acom flow and Pcom flow (12.0% ± 6.0%) than in patients with Acom flow and Pcom flow (3.0% ± 3.1%, P < 0.01) and in patients with Acom flow but no Pcom flow (2.4% ± 5.2%, P < 0.01). CONCLUSIONS: These findings support the importance of Acom flow as a collateral route. ICA-selective MRA enables prediction of ischemic intolerance to temporary ICA occlusion during carotid endarterectomy or carotid artery stenting. This method provides valuable information regarding probability of an ischemic complication.

  Oct. 2019, World neurosurgery, 130, e899-e907, English, International magazine

  [Refereed]

  Link to Kobe Univ. Repository (Kernel)


• Thrombosed Middle Meningeal Artery Aneurysms Mimicking Aneurysmal Bone Cysts in a Patient with Fibrous Dysplasia.

  Shunsuke Yamashita, Hidehito Kimura, Masaaki Kohta, Atsushi Fujita, Eiji Kohmura

  BACKGROUND: The aneurysmal bone cyst (ABC) is a rare osteolytic lesion that is often associated with osseous disease such as fibrous dysplasia (FD). CASE DESCRIPTION: A 66-year-old woman previously diagnosed with FD presented with suddenly reduced visual acuity. Computed tomography and magnetic resonance imaging revealed a large osteolytic lesion in the middle cranial fossa that had invaded the left orbit. Although its radiological findings were compatible with an ABC, rotational digital subtraction angiography revealed that this osteolytic lesion was a large middle meningeal artery (MMA) aneurysm. To release the compression force on the optic nerve and confirm the diagnosis, we performed endovascular embolization, followed by surgical removal of the lesion. Histologic examination revealed that the resected lesion met the requirements of a thrombosed aneurysm. No new neurologic deficits appeared after the surgery, and no symptomatic recurrence have been noted during the 6-month follow-up. CONCLUSIONS: This is the first case report to show that ABC-like lesions in patients with FD could be thrombosed MMA aneurysms. It is thus possible that some lesions previously diagnosed as ABCs were thrombosed MMA aneurysms or included a thrombosed MMA aneurysm. It is therefore important to rule out the presence of a MMA aneurysm when we encounter what appears to be an ABC in the presence of FD.

  Oct. 2019, World neurosurgery, 130, 439 - 443, English, International magazine

  [Refereed]


• Application of a Minimally Invasive Liposuction Technique for Harvesting Fat during Transsphenoidal Surgery: A Technical Note.

  Yuichi Fujita, Masaaki Taniguchi, Takashi Tsuzuki, Tomoaki Nakai, Yoichi Uozumi, Hidehito Kimura, Eiji Kohmura

  Secure reconstruction in transsphenoidal surgery (TSS) is important for the prevention of the major and serious complication of postoperative cerebrospinal fluid (CSF) leak. Although abdominal fat can be safely and effectively used as a reconstruction tissue, harvesting it from the abdominal wall is traumatic and invasive, resulting in cosmetic problems. In this report, we present a method of harvesting abdominal fat using a minimally invasive liposuction technique to avoid cosmetic issues. Since 2016, we have been using fat harvested from the abdominal wall by suctioning with a dedicated syringe for reconstruction after TSS in selected cases. The liquefied fat obtained by the liposuction technique was wrapped with an oxycellulose sheet and changed its form to what we termed "fatty candy". In this form, the fat maintained its configuration and could be handled almost as easily as a conventional fat graft. In our experienced series, there was no case with wound complication nor postoperative or late-onset CSF leak during a postoperative follow-up of at least 3 months. The fat harvested by this simple and minimally invasive liposuction technique can be expected to provide an autologous graft that is adequate not only for prevention of cosmetic problems but also for prevention of postoperative CSF leak.

  May 2019, Neurologia medico-chirurgica, 59(5) (5), 184 - 190, English, Domestic magazine

  [Refereed]

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Numerical Simulations of Flows in Cerebral Aneurysms Using the Lattice Boltzmann Method with Single- and Multiple-Relaxation Time Collision Models

  OSAKI SUSUMU, HAYASHI KOSUKE, KIMURA HIDEHITO, SETA TAKESHI, KOHMURA EIJI, TOMIYAMA AKIO

  May 2019, Computers & Mathematics with Applications, in press, English

  [Refereed]

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Detection of Hemodynamic Characteristics Before Growth in Growing Cerebral Aneurysms by Analyzing Time-of-Flight Magnetic Resonance Angiography Images Alone: Preliminary Results.

  Hidehito Kimura, Kosuke Hayashi, Masaaki Taniguchi, Kohkichi Hosoda, Atsushi Fujita, Takeshi Seta, Akio Tomiyama, Eiji Kohmura

  OBJECTIVE: Cerebral aneurysm growth often precedes rupture. Definite contributors to aneurysm growth have not been determined even by means of recently developed commercially available computational fluid dynamics (CFD) software. We developed an original CFD tool that can analyze data from time-of-flight magnetic resonance angiography (TOF-MRA) before growth in the growing aneurysms and investigate possible factors for aneurysm growth in the near future. METHODS: We retrospectively reviewed unruptured aneurysms that were treated at our institute because of aneurysm growth (growing group) between April 2013 and March 2017. Stable aneurysms that had demonstrated no growth for more than 5 years were selected (stable group). TOF-MRA data of these aneurysms were retrospectively converted to 3-dimensional vessel geometric data; 3 hemodynamic indices including streamline, wall shear stress (WSS), and oscillatory shear index were calculated by our original CFD tool using the lattice Boltzmann method to quantitatively compare the 2 groups. RESULTS: Six growing aneurysms and 6 stable aneurysms were analyzed. Of the 6 growing aneurysms, WSS on the focal aneurysmal sac increased temporally in the vicinity of the constant low WSS area at the peak systolic phase. By contrast, WSS did not increase during any part of the cardiac cycle in 3 of the 6 stable aneurysms. The peak values of WSS were significantly different between the 2 groups. CONCLUSIONS: A focal increase in WSS in the peak systolic phase may be a risk factor for aneurysm enlargement in the near future.

  Feb. 2019, World neurosurgery, 122, e1439-e1448 - e1448, English, International magazine

  [Refereed]

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Clear Detection of Thin-Walled Regions in Unruptured Cerebral Aneurysms by Using Computational Fluid Dynamics.

  Hidehito Kimura, Masaaki Taniguchi, Kosuke Hayashi, Yosuke Fujimoto, Youichi Fujita, Takashi Sasayama, Akio Tomiyama, Eiji Kohmura

  OBJECTIVE: Thin-walled regions (TIWRs) within cerebral aneurysms have a high risk of rupture during surgical manipulation. Previous reports have demonstrated specific changes in the parameters of computational fluid dynamics in TIWRs; however, they have not been fully evaluated. We identified and investigated a novel parameter, wall shear stress vector cycle variation (WSSVV), with user-friendly software that could predict TIWRs. METHODS: Twelve unruptured cerebral aneurysms were analyzed. TIWRs were defined as reddish areas compared with the normal-colored parent artery on intraoperative views. The position and orientation of these clinical images were adjusted to match the WSSVV color maps. TIWRs and thick-walled regions (TKWRs) were marked and compared with the corresponding regions on WSSVV maps. The default images obtained from WSSVV imaging required appropriate maximum color bar value (MCBV) adjustment for predicting TIWRs. Sensitivity and specificity analyses were performed by changing the MCBV from 300 to 700 at intervals of 100. With the optimal MCBV, the WSSVV values were quantitatively compared. RESULTS: All of the selected 18 TIWRs and 16 TKWRs corresponded to low- and high-value regions of the WSSVV color maps at the adjusted MCBV, respectively. The mean optimal MCBV was 483.3 ± 167.50 (range, 300-700). According to receiver operating characteristic analysis, the best MCBV for predicting TIWRs was 500 (highest sensitivity, 0.89; specificity, 0.94). Under this condition, the quantitative values of the computational fluid dynamics color maps for TIWRs and TKWRs were significantly different (P < 0.01). CONCLUSIONS: Low WSSVV values may indicate TIWRs within cerebral aneurysms.

  Jan. 2019, World neurosurgery, 121, e287-e295 - e295, English, International magazine

  [Refereed]

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• AIの機械学習を用いて頸動脈狭窄症の治療後転帰を予測する

  松尾和哉, 藤田敦史, 細田弘吉, 田中潤, 今堀太一郎, 石井大嗣, 甲田将彰, 田中一寛, Kimura Hidehito, 甲村英二

  (NPO)日本脳神経血管内治療学会, Nov. 2018, 脳血管内治療, 3(Suppl.) (Suppl.), S115 - S115, Japanese

  Research society


• 海綿静脈洞進展下垂体腺腫摘出における内頸動脈蛇行の影響について

  TANIGUCHI MASAAKI, NAKAI TOMOAKI, KIMURA HIDEHITO, KOHMURA EIJI

  (一社)日本内分泌学会, Sep. 2018, 日本内分泌学会雑誌, 94(Suppl.HPT) (Suppl.HPT), 75 - 77, Japanese

  [Refereed]


• Complications in Salvage Surgery for Nasal and Paranasal Malignant Tumors Involving the Skull Base.

  Masanori Teshima, Hirotaka Shinomiya, Naoki Otsuki, Hidehito Kimura, Masaaki Taniguchi, Kazunobu Hashikawa, Eiji Kohmura, Ken-Ichi Nibu

  Objective  Nasal and paranasal malignant tumors invading the skull base are rare and poorly studied. We evaluated postoperative complications in patients undergoing salvage surgery for such tumors. Design  Retrospective study. Setting  Kobe University Hospital. Participants  Among 48 patients who underwent surgery for tumors involving the skull base between 1993 and 2015, 21 patients had squamous cell carcinoma, 13 had olfactory neuroblastoma, 5 had adenocarcinoma, 2 had sarcoma, 2 had adenoid cystic carcinoma, and 1 each had malignant melanoma, poorly differentiated carcinoma, undifferentiated carcinoma, myoepithelial carcinoma, and malignant peripheral nerve sheath tumor. Prior to skull base surgery, radiotherapy, chemoradiotherapy (CRT), particle radiotherapy, chemotherapy, or surgery were applied in 3, 15, 4, 5, and 3 patients, respectively. Main Outcome Measures  Main outcome measures were postoperative complications in patients who underwent skull base surgery after concomitant CRT and/or particle therapy. Results  Major postoperative complications were observed in 14 surgical procedures (29%; 2 patients with cerebral herniation, 3 with cerebrospinal fluid leakages, 3 with meningitis, 1 with hydrocephalus, 6 with epidural abscesses, 2 with local infections, and 2 with partial flap necrosis). Four patients developed ≥2 complications. One patient died of postoperative lung infarction. Three (16.7%) of 18 patients without prior treatment and 9 (50%) of 18 patients who underwent preoperative radiotherapy/CRT had severe postoperative complications. Two (50%) of four patients treated with particle radiotherapy had postoperative complications. Conclusions  CRT or particle radiotherapy were significantly associated with a high risk of severe postoperative complications after skull base surgery. Meticulous care should be taken in patients treated with radiotherapy/particle therapy prior to skull base surgery.

  Jun. 2018, Journal of neurological surgery. Part B, Skull base, 79(3) (3), 224 - 228, English, International magazine

  [Refereed]

  Scientific journal


• Endoscopic endonasal surgery for pituitary adenomas extending to the oculomotor cistern.

  Masaaki Taniguchi, Tomoaki Nakai, Hidehito Kimura, Yuichi Fujita, Yoichi Uozumi, Masaaki Kohta, Eiji Kohmura

  BACKGROUND: Extension of a pituitary adenoma to the oculomotor cistern harbors the risk of oculomotor nerve impairment and further extension into the interpeduncular cistern. The role of endoscopic endonasal surgery for those lesions was investigated. METHODS: The medical records were retrospectively analyzed. Attention was paid to the oculomotor nerve function and removal rate of the tumor within the oculomotor and interpeduncular cisterns. RESULTS: Six patients were eligible for the study, including 2 with oculomotor nerve palsy. The tumor from the oculomotor and interpeduncular cistern was removed in all except on one side of the case with bilateral tumor extension. The oculomotor nerve palsy demonstrated partial recovery in both cases during the 3-month follow-up. CONCLUSION: The pituitary adenoma extending to the oculomotor cistern can be removed under the endoscope. Improvement of oculomotor nerve palsy can be achieved, and further tumor extension into the interpeduncular cistern can be prevented.

  Mar. 2018, Head & neck, 40(3) (3), 536 - 543, English, International magazine

  [Refereed]

  Scientific journal


• 下垂体腺腫の海綿静脈洞部動眼神経孔進展の臨床的意義について

  谷口理章, 木村英仁, 中井友昭, Kohmura Eiji

  (一社)日本内分泌学会, Oct. 2017, 日本内分泌学会雑誌, 93(Suppl.HPT) (Suppl.HPT), 82 - 84, Japanese

  [Refereed]


• Clinical Implication of Temporary Hypointense Lesion on Diffusion-Weighted Imaging After Extracranial-Intracranial Bypass Surgery

  Hidehito Kimura, Masaaki Taniguchi, Tatsuya Mori, Kohkichi Hosoda, Eiji Kohmura

  Jan. 2017, WORLD NEUROSURGERY, 97, 754, English

  [Refereed]

  Scientific journal


• Communicating Hydrocephalus Associated with Small- to Medium-Sized Vestibular Schwannomas: Clinical Significance of the Tumor Apparent Diffusion Coefficient Map.

  Masaaki Taniguchi, Tomoaki Nakai, Masaaki Kohta, Hidehito Kimura, Eiji Kohmura

  BACKGROUND: The etiology of hydrocephalus associated with the small- to medium-sized vestibular schwannomas is still controversial. We investigated tumor-specific factors related to the association of hydrocephalus with small- to medium-sized vestibular schwannomas. METHODS: Among the 77 patients with vestibular schwannoma smaller than 30 mm, 9 patients demonstrated associated communicating hydrocephalus. Patient medical records, radiologic data, and histopathologic specimens were reviewed retrospectively. The age of the patients, and size, mean apparent diffusion coefficient (ADC) value, and histologic features of the tumors were compared with those of patients without hydrocephalus. RESULTS: The symptoms related to hydrocephalus improved in all patients after tumor removal. Both the mean size and ADC values exhibited a statistically significant difference between the tumors with and without hydrocephalus (P < 0.01). CONCLUSIONS: The size and ADC value of the tumor were significantly related to the association with hydrocephalus. The increased tumor ADC value was considered to be the result of degenerative change and suggested the involvement of protein sloughing in the etiology of the associated hydrocephalus.

  Oct. 2016, World neurosurgery, 94, 261 - 267, English, International magazine

  [Refereed]

  Scientific journal


• Minimum Transpetrosal Retrolabyrinthine Approach for Revascularization of Posterior Cerebral Artery: Operative Nuance

  Hidehito Kimura, Masaaki Taniguchi, Junji Koyama, Yousuke Fujimoto, Kohkichi Hosoda, Eiji Kohmura

  Jun. 2016, OPERATIVE NEUROSURGERY, 12(2) (2), 112 - 118, English

  [Refereed]

  Scientific journal


• Endoscopic endonasal translacerum approach to the inferior petrous apex.

  Masaaki Taniguchi, Nobuyuki Akutsu, Katsu Mizukawa, Masaaki Kohta, Hidehito Kimura, Eiji Kohmura

  OBJECTIVE: The surgical approach to lesions involving the inferior petrous apex (IPA) is still challenging. The purpose of this study is to demonstrate the anatomical features of the IPA and to assess the applicability of an endoscopic endonasal approach through the foramen lacerum (translacerum approach) to the IPA. METHODS: The surgical simulation of the endoscopic endonasal translacerum approach was conducted in 3 cadaver heads. The same technique was applied in 4 patients harboring tumors involving the IPA (3 chordomas and 1 chondro-sarcoma). RESULTS: By removing the fibrocartilaginous component of the foramen lacerum, a triangular space was created between the anterior genu of the petrous portion of the carotid artery and the eustachian tube, through which the IPA could be approached. The range of the surgical maneuver reached laterally up to the internal auditory canal, jugular foramen, and posterior vertical segment of the petrous portion of the carotid artery. In clinical application, the translacerum approach provided sufficient space to handle tumors at the IPA. Gross-total and partial removal was achieved in 3 and 1 cases, respectively, without permanent surgery-related morbidity and mortality. CONCLUSIONS: The endoscopic endonasal translacerum approach provides reliable access to the IPA. It is indicated alone for lesions confined to the IPA and in combination with other approaches for more extensive lesions.

  Apr. 2016, Journal of neurosurgery, 124(4) (4), 1032 - 8, English, International magazine

  [Refereed]

  Scientific journal


• Long-Term Outcomes of Carotid Endarterectomy and Carotid Artery Stenting for Carotid Artery Stenosis: Real-World Status in Japan.

  Taichiro Imahori, Kohkichi Hosoda, Atsushi Fujita, Yusuke Yamamoto, Takashi Mizowaki, Shigeru Miyake, Hidehito Kimura, Masaaki Kohta, Eiji Kohmura

  BACKGROUND AND PURPOSE: We investigated long-term outcomes of carotid endarterectomy (CEA) and carotid artery stenting (CAS) in our institute to evaluate the outcomes of real-world practice in Japan. METHODS: Between August 2006 and July 2013, 203 consecutive carotid revascularizations with either CEA or CAS were performed in our institute. The initial treatment was regarded as the starting point in the cases of the patients who received treatment by bilateral carotid artery stenosis or retreatment. We assessed the long-term outcomes with survival analyses. RESULTS: A total of 182 patients (CEA 111, CAS 71), including 86 symptomatic patients, were included in the current study with a mean follow-up period of 42.9 months. The periprocedural stroke/death/myocardial infarction (MI) rate was 3.6% for CEA and 5.6% for CAS groups (P = .71). Estimates of the 4-year event-free rate from the primary end point (the composite of any stroke, death, or MI within 30 days, and any ipsilateral stroke thereafter) using competing risk analysis were 3.6% for CEA and 7.1% for CAS (P = .156). Kaplan-Meier estimates of the 4-year event-free rate from the secondary end point (the composite of any stroke, death, or MI within 30 days, and any stroke or death thereafter) were 13.8% for CEA and 19.1% for CAS (P = .072). Age was the only significant predictor for the primary end point. Both age and CAS were significant predictors for the secondary end point. CONCLUSIONS: The current study on real-world practices demonstrated perioperative and long-term outcomes that were comparable to previous major studies of large numbers of patients.

  Feb. 2016, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 25(2) (2), 360 - 7, English, International magazine

  [Refereed]

  Scientific journal


• Radiographic occult cerebellar germinoma presenting with progressive ataxia and cranial nerve palsy

  Noriaki Minami, Kazuhiro Tanaka, Hidehito Kimura, Takanori Hirose, Tatsuya Mori, Masahiro Maeyama, Hiroaki Sekiya, Takeshi Uenaka, Satoshi Nakamizo, Hiroaki Nagashima, Katsu Mizukawa, Tomoo Itoh, Takashi Sasayama, Eiji Kohmura

  Jan. 2016, BMC NEUROLOGY, 16(1) (1), 4, English

  [Refereed]

  Scientific journal


• 【頸動脈狭窄症に関する諸問題】 無症候性頸動脈狭窄症に対する手術治療の現状と課題

  細田弘吉, Fujita Atsushi, 木村英仁, Kota Masaaki, 阿久津宣行, Kohmura Eiji

  (一社)日本脳卒中の外科学会, May 2015, 脳卒中の外科, 43(3号) (3号), 175 - 180, Japanese

  [Refereed]


• 自己血液から作製した灌流液による血管グラフトの術中灌流・保存

  Kimura Hidehito, 細田 弘吉, Kohmura Eiji

  Feb. 2015, Neurological Surgery, 43(2号) (2号), 109 - 115, Japanese

  [Refereed]

  Scientific journal


• Use of heparinized autologous blood for intraoperative rinsing and storage of vascular grafts

  Hidehito Kimura, Kohkichi Hosoda, Eiji Kohmura

  Igaku-Shoin Ltd, Feb. 2015, Neurological Surgery, 43(2) (2), 109 - 115, Japanese

  [Refereed]

  Scientific journal


• 頸動脈狭窄症に対する血行再建術(CEA/CAS)の中長期成績

  今堀 太一郎, 細田 弘吉, 藤田 敦史, 山本 祐輔, 木村 英仁, Kota Masaaki, 鵜山 淳, Kohmura Eiji

  Dec. 2014, JNET: Journal of Neuroendovascular Therapy, 8(6号) (6号), 234, Japanese

  [Refereed]

  Research society


• 80歳以上くも膜下出血患者への脳動脈瘤直達術の治療成績

  Kimura Hidehito, 三宅 茂, 千葉義幸, 小山淳二, 甲田将章, 甲村英二

  (一社)日本脳卒中の外科学会, Mar. 2014, 脳卒中の外科, 42(2) (2), 103 - 108, Japanese

  [Refereed]

  Scientific journal


• Cilostazol administration with combination enteral and parenteral nutrition therapy remarkably improves outcome after subarachnoid hemorrhage

  Hidehito Kimura, Yusuke Okamura, Yosiyuki Chiba, Miyake Shigeru, Taiji Ishii, Tatsuo Hori, Ryoji Shiomi, Yuusuke Yamamoto, Yousuke Fujimoto, Masahiro Maeyama, Eiji Kohmura

  Springer-Verlag Wien, 2014, Acta Neurochirurgica, Supplementum, 120, 147 - 152, English

  [Refereed]

  Scientific journal


• Subarachnoid Hemorrhage Caused by Ruptured Intracranial Fusiform Aneurysm Associated With Microscopic Polyangiitis -Case Report-

  Hidehito Kimura, Nobuyuki Akutsu, Ryoji Shiomi, Eiji Kohmura

  Jul. 2012, NEUROLOGIA MEDICO-CHIRURGICA, 52(7) (7), 495 - 498, English

  [Refereed]

  Scientific journal


• Vestibular dysfunction and compensation after removal of acoustic neuroma

  Natsumi Uehara, Hitoshi Tanimoto, Tasuku Nishikawa, Kiyoshi Doi, Sayaka Katsunuma, Hidehito Kimura, Eiji Kohmura, Ken-ichi Nibu

  2011, JOURNAL OF VESTIBULAR RESEARCH-EQUILIBRIUM & ORIENTATION, 21(5) (5), 289 - 295, English

  [Refereed]

  Scientific journal


• A very unusual case of fibromuscular dysplasia with multiple aneurysms of the vertebral artery and posterior inferior cerebellar artery Case report

  Hidehito Kimura, Kohkichi Hosoda, Yoshie Hara, Eiji Kohmura

  Dec. 2008, JOURNAL OF NEUROSURGERY, 109(6) (6), 1108 - 1112, English

  [Refereed]

  Scientific journal


• Effect of Anticoagulant or Antiplatelet Therapy on Outcome after Intracerebral Hemorrhage

  MOTOOKA Yasuhiko, MIZOBE Takashi, KIMURA Hidehito, SAITOH Minoru, KAWAGUCHI Tetsuro, Yasuhiko MOTOOKA, Takashi MIZOBE, Hidehito KIMURA, Minoru SAITOH, Tetsuro KAWAGUCHI, Department of Neurosurgery Hyogo Brain and Heart Center, Department of Neurosurgery Hyogo Brain and Heart Center, Department of Neurosurgery Hyogo Brain and Heart Center, Department of Neurosurgery Hyogo Brain and Heart Center, Department of Neurosurgery Hyogo Brain and Heart Center

  We investigated whether pretreatment of anticoagulant agents and antiplatelet agents affect the prognosis in patients with intracerebral hemorrhage (ICH).
  We retrospectively reviewed the medical records of 451 patients admitted to our center due to intracerebral hemorrhage within 24 hours after onset during an 8-year period from 1998 to 2005. The ICH patients were divided into 4 groups: patients with anticoagulant therapy (AC, 20 patients), with antiplatelet therapy (AP, 47 patients), with combined anticoagulant and antiplatelet therapy (AC+AP, 8 patients), and with no pretreatment (NT, 376 patients). We also selected 345 patients with ICH who had undergone a second CT within 24 hours of initial scan and evaluated the hematoma volume in each scan and the ratio of hematoma enlargement. The AC+AP group showed a worse prognosis and higher in-hospital mortality than the NT group. Meanwhile, the AC and AP group showed no tendency of higher mortality or poor prognosis.
  Pretreatment of combination of warfarin and aspirin is associated with poor prognosis and higher mortality in patients with ICH.
  

  The Japanese Society on Surgery for Cerebral Stroke, Mar. 2008, Nosotchu no Geka Kenkyukai koenshu, 36(2) (2), 100 - 105, Japanese


• Ultra-early Treatment for Poor-grade Patients with Subarachnoid Hemorrhage

  HOSODA Kohkichi, NAKAMURA Yosie, WADA Taro, KIMURA Hidehito, OHTA Kohei, KOHMURA Eiji

  Indications for treatment for poor-grade patients with subarachnoid hemorrhage (SAH) are still controversial. As an emergency center, our hospital admits many poor-grade patients with SAH at ultra-early stage. We have difficulty with the rationale of allowing these patients to have unsecured aneurysms during the peak rebleeding period to see which ones are likely to spontaneously improve. In this study, we report the results of ultra-early treatment for poor-grade patients with SAH. Between August 2003 and March 2005, our hospital admitted 73 patients with SAH. Fifty-two of them (71%) who had WFNS Grade IV (14) and V (38) were analyzed in this study. Patients were not selected based on age (mean age 63.1 years ranging from 27-91). After stable vital parameters were established, the patients underwent radiological examination and surgical treatment for aneurysms in the anterior circulation or endovascular treatment for aneurysms in the posterior circulation as soon as possible.
  Outcomes were assessed at 3 months after SAH onset. Forty-six (88%) of 52 poor-grade patients were admitted within 90 minutes after SAH onset. Despite the aggressive management policy, definitive treatment could be given in only 32 patients (62%). The treatment was initiated within 9 hours after SAH onset in 26 patients (81%). Clipping was performed in 19 patients and endovascular coil embolization in 13. Overall mortality was 52%, and overall good outcomes (good recovery+moderate disability) were obtained in 25%. All 17 patients resuscitated after cardiopulmonary arrest (CPA) had Grade V and died with or without treatment. On the other hand, good outcomes were obtained in 37% and mortality was 29% in 35 patients without CPA. However, 4 of the 35 (11%) died because of ultra-early rebleeding. In patients with Grade IV, mortality was 7% and good outcomes were obtained in 50%. In patients with Grade V, mortality was 68% and good outcomes were obtained in 16%.
  The outcomes of ultra-early treatment in poor-grade patients with SAH suggest that a non-selective policy of treatment as early as possible provides acceptable results, especially in Grade IV. However, definitive treatment should not be performed for patients with CPA because there is no chance to save them.
  

  The Japanese Society on Surgery for Cerebral Stroke, 2007, Nosotchu no Geka Kenkyukai koenshu, 35(1) (1), 7 - 12, Japanese


• Endovascular treatment for a unusually large mycotic aneurysm manifesting as intracerebral hemorrhage - Case report

  Yoshie Hara, Kohkichi Hosoda, Taro Wada, Hidehito Kimura, Eiji Kohmura

  Nov. 2006, NEUROLOGIA MEDICO-CHIRURGICA, 46(11) (11), 544 - 547, English

  [Refereed]

  Scientific journal


• Surgical Results of Carotid Endarterectomy for Asymptomatic Carotid Stenosis: 100 Consecutive Cases

  KAWAGUCHI Tetsuro, SHIBATA Yuji, KIMURA Hidehito, ARAI Atsushi, KOHMURA Eiji, Tetsuro KAWAGUCHI, Yuji SHIBATA, Hidehito KIMURA, Atsushi ARAI, Eiji KOHMURA, Department of Neurosurgery Hyogo Brain and Heart Center at Himeji, Department of Neurosurgery Hyogo Brain and Heart Center at Himeji, Department of Neurosurgery Hyogo Brain and Heart Center at Himeji, Department of Neurosurgery Hyogo Brain and Heart Center at Himeji, Department of Neurosurgery Kobe University Graduate School of Medicine

  We performed the CEA for 100 consecutive patients of asymptomatic carotid stenosis from May 1993 to December 2004. There were 81 men and 19 women (48-83 years old) with a mean age of 69. The high cervical lesion (distal end is higher than C2 vertebral body) was recognized in 14 patients and contralateral occlusion was seen in 12 pacients. Five patients were over 80 years old. Fifty-five patients had coronary heart disease, and 21 patients received coronary artery bypass. Another 21 patients had percutaneous coronary intervention before CEA. Of the 42 patients treated for coronary artery disease, 16 patients had no history of previous ischemic heart attack. The electroencephalogram and the flow of internal shunt were monitored during operation. Although perioperative morbidity was 2% and there was no mortality, transient complications were recognized. Two patients had transient hemiparesis; 8 had cranial nerve palsy; 1 had postoperative arteriovenous fistula; 1 had mild acute myocardial infarction; 2 had wound infections; and there were 4 hematomas (2 operations).
  To minimize complications, preoperative examination of the coronary artery disease, meticulous operative procedures and prevention of hyperperfusion syndrome are important.
  

  The Japanese Society on Surgery for Cerebral Stroke, Sep. 2006, Nosotchu no Geka Kenkyukai koenshu, 34(5) (5), 360 - 365, Japanese


• 急速な縮小を見た重症急性硬膜下血腫の超高齢者の一例

  木村英仁, 野垣秀和, 澤 秀樹, 玉木紀彦

  Lead, 2000, 脳神経外科ジャーナル, 9, 561 - 564, Japanese

  [Refereed]

  Scientific journal


• Idiopathic spinal cord herniation. Report of two cases and review of the literature

  S Miyake, N Tamaki, T Nagashima, H Kurata, T Eguchi, H Kimura

  Corresponding, 1999, Neurosurg Focus, 7(5) (5), e6, English

  [Refereed]

  Scientific journal


• Idiopathic spinal cord herniation. Report of two cases and review of the literature

  S Miyake, N Tamaki, T Nagashima, H Kurata, T Eguchi, H Kimura

  Corresponding, Feb. 1998, J Neurosurg, 88(2) (2), 331 - 335, English

  [Refereed]

  Scientific journal


• 1. 電気分離脱コイル（Guglielmi detachable coil; GDC）を用いて治療し得た脳底動脈先端部動脈瘤の1症例

  木村英仁, 野垣秀和, 富永正吾, 澤 秀樹

  Lead, 1997, 公立豊岡病院紀要, 9, 35 - 39, Japanese

  Research institution

• A case of facial schwannoma with extensive destruction and infiltration of the temporal bone: Strategies and challenges for radical resection

  下田光, 柿木章伸, 横井純, 上原奈津美, 藤田岳, 橋川和信, 木村英仁, 丹生健一

  2022, Facial Nerve Research Japan, 41


• 傍鞍部大型腫瘍に対する開頭・経鼻内視鏡二期的手術の有用性について

  谷口 理章, 木村 英仁, 甲村 英二

  (一社)日本内分泌学会, Sep. 2021, 日本内分泌学会雑誌, 97(Suppl.HPT) (Suppl.HPT), 7 - 9, Japanese


• 経鼻頭蓋底手術における3T-術中MRIの有効性について

  谷口 理章, 木村 英仁, 甲村 英二

  日本脳神経CI学会, Sep. 2021, CI研究, 43(2) (2), 75 - 80, Japanese


• 内頸動脈狭窄症におけるBeam SAT MRAによる術前脳血流循環動態評価の有効性

  山下 俊輔, 甲田 将章, 田中 潤, 細田 弘吉, 木村 英仁, 藤田 敦史, 篠山 隆司

  (一社)日本脳循環代謝学会, Nov. 2020, 脳循環代謝, 32(1) (1), 105 - 105, Japanese


• 視機能障害で発症した鞍部・傍鞍部炎症性疾患に対し経鼻内視鏡手術を行った6症例

  三浦 伸一, 魚住 洋一, 谷口 理章, 中井 友昭, 木村 英仁, 甲村 英二

  (株)医学書院, Oct. 2020, Neurological Surgery, 48(10) (10), 915 - 920, Japanese


• AIの機械学習で頸動脈狭窄症治療後早期の転帰を予測する 実臨床での応用

  松尾 和哉, 藤田 敦史, 細田 弘吉, 田中 潤, 今堀 太一郎, 石井 大嗣, 甲田 将章, 田中 一寛, 魚住 洋一, 木村 英仁, 甲村 英二

  (NPO)日本脳神経血管内治療学会, Nov. 2019, 脳血管内治療, 4(Suppl.) (Suppl.), S212 - S212, Japanese


• 【Hybrid Neurosurgeonのための疾患別臨床脳血管解剖テキスト】(第1章)開頭手術と血管内治療の選択 脳動脈瘤 IC-AChA IC-AChAの開頭手術

  木村 英仁, 甲村 英二

  (株)メディカ出版, Sep. 2018, 脳神経外科速報, (2018増刊) (2018増刊), 36,38,40,42,44,46,48 - 36,38,40,42,44,46,48, Japanese


• Long-term Outcomes of Carotid Endarterectomy and Carotid Artery Stenting: Real-World Status of Single Institute in Japan

  Kohkichi Hosoda, Taichiro Imahori, Atsushi Fujita, Yusuke Yamamoto, Hidehito Kimura, Masaaki Kohta, Eiji Kohmura

  Feb. 2016, STROKE, 47, English

  Summary international conference


• 脳神経外科診療における疼痛管理を目的としたアセトアミノフェン静注の有用性

  鵜山 淳, 甲田 将章, 田中 一寛, 水川 克, 木村 英仁, 藤田 敦史, 篠山 隆司, 谷口 理章, 細田 弘吉, 甲村 英二

  (一社)日本頭痛学会, Nov. 2014, 日本頭痛学会誌, 41(2) (2), 276 - 276, Japanese


• 特発性脊椎硬膜外血腫の2例

  河野 淳, 藤井 正彦, 杉村 和朗, 祖父江 慶太郎, 宮本 直和, 石井 一成, 木村 英仁, 本岡 康彦, 川口 哲郎

  (公社)日本医学放射線学会, Sep. 2006, 日本医学放射線学会秋季臨床大会抄録集, 42回, S518 - S518, Japanese

• 5th WINTER SEMINAR OF CEREBROVASCULAR DISEASE / How to dissect the sylvian fissure & preserve important neurovascular structure - For the treatment of anterior circulation aneurysms in the pterional approach

  Kimura Hidehito, EijiKohmura

  Others, BANTANE HOSPITAL, Jan. 2019, English

  Scholarly book


• Hybrid Neurosurgeonのための疾患別臨床脳血管解剖テキスト / IC-AChAの開頭手術

  Kimura Hidehito, 甲村英二

  Others, メディカ出版, Sep. 2018, Japanese

  Scholarly book


• 3rd WINTER SEMINAR OF CEREBROVASCULAR DISEASE / How to dissect the sylvian fissure & preserve important neurovascular structure - For the treatment of anterior circulation aneurysms in the pterional approach

  Kimura Hidehito, EijiKohmura

  Others, Fujita University Hospital Banbuntane Hotokukai Hospital, Jan. 2017, English

  Textbook


• シュミレーションで経験する手術・IVR 前大脳動脈瘤・椎骨脳底動脈瘤のすべて / 椎骨動脈瘤 解離（バイパス併用）

  Kimura Hidehito, 甲村英二

  Others, メディカ出版, May 2016, Japanese

  Textbook


• Textbook of 2nd Winter Seminar of cerebrovascular disease / How to dissect the sylvian fissure & preserve important neurovascular structure - For the treatment of anterior circulation aneurysms in the pterional approach -. 2st Bantane Winter Seminar 2015

  Kimura Hidehito, KohmuraE

  Others, Banbuntane Hotokukai Hospital, Jan. 2016, English

  Scholarly book


• VIDEO JOURNAL of Japan Neurosurgery 22(4), 2015

  Joint work, 2015


• ACNS Surgical Manual / Distal transsylvian approach for the cerebral aneurysm surgery

  Kimura Hidehito, Eiji Kohmura

  Others, Quill Design, 2014, English

  Textbook


• 1st Bantane Winter Seminar / How to dissect the sylvian fissure & preserve important neurovascular structure - For the treatment of anterior circulation aneurysms in the pterional approach -

  Kimura Hidehito

  Others, Banbuntane Hotokukai Hospital, 2014, English

  Textbook


• カンファレンスストーリーで覚える脳外科疾患

  Joint work, 巨大髄膜種の周術期看護のポイント, 日総研出版, 2011

• Current aneurysm clipping on preoperative simulation for reduced uncertainty and improved techniques for upgraded safety in endovascular era

  Hidehito Kimura, M.D., Ph.D, Tatsuya Mori M.D, Kosuke Hayashi, D.Eng, Akio Tomiyama, D.Eng, Takashi Sasayama, M.D., Ph.D

  ACNS Red River Bootcamp 2023, English

  [Invited]

  Nominated symposium


• Bypass surgery -step by step- for reliable revascularization

  Hidehito Kimura

  WFNS Foundation ACNS Autumn Web seminar, Nov. 2021, English

  Invited oral presentation


• CFDを用いた瘤壁菲薄部可視化による脳動脈瘤固有の破裂予測

  KIMURA HIDEHITO, TANIGUCHI MASAAKI, KOHMURA EIJI

  第42回日本脳神経CI学会総会, Mar. 2019, Japanese, 六本木, Domestic conference

  Oral presentation


• CFDによる脳動脈瘤固有の破裂予測：流線と壁菲薄部位からの後方視的検討

  KIMURA HIDEHITO, TANIGUCHI MASAAKI, KOHMURA EIJI

  第48回脳卒中の外科学会, Mar. 2019, Japanese, 横浜, Domestic conference

  Oral presentation


• 視機能障害で発症した鞍部・傍鞍部炎症性疾患に対する経鼻内視鏡手術成績

  UOZUMI YOICHI, TANIGUCHI MASAAKI, NAKAI TOMOAKI, KOHTA MASAAKI, KIMURA HIDEHITO, KOHMURA EIJI

  第29回日本間脳下垂体腫瘍学会, Feb. 2019, Japanese, 大阪, Domestic conference

  Oral presentation


• 海綿静脈洞進展下垂体腺腫に対する経鼻内視鏡下摘出術

  TANIGUCHI MASAAKI, NAKAI TOMOAKI, UOZUMI YOICHI, KIMURA HIDEHITO, KOHMURA EIJI

  第29回 日本間脳下垂体腫瘍学会, Feb. 2019, Japanese, 大阪, Domestic conference

  Public symposium


• Visibility of thin-walled region of cerebral aneurysms using computational fluid dynamics

  Hidehito Kimura, Eiji Kohmura

  Premier FUJITA-BANBUNTANE 5th Winter Seminar, Feb. 2019, English, 名古屋, International conference

  [Invited]

  Invited oral presentation


• Visibility of thin-walled region of cerebral aneurysms using computational fluid dynamics

  Hidehito Kimura, Eiji Kohmura

  International ediucational course: cerebral revascularization with hands-on workshop in microvascular anastomosis, Feb. 2019, English, Tyumen, International conference

  [Invited]

  Invited oral presentation


• Significance of extracranial - intracranial high flow bypass with trapping for ruptured ICA anterior wall aneurysms in the super-acute phase

  Hidehito Kimura, Eiji Kohmura

  Premier FUJITA-BANBUNTANE 5th Winter Seminar, Feb. 2019, English, 名古屋, International conference

  [Invited]

  Invited oral presentation


• Clinical application of skull base surgeryfor cerebrovascular lesion

  Hidehito Kimura, Eiji Kohmura

  International ediucational course: cerebral revascularization with hands-on workshop in microvascular anastomosis, Feb. 2019, English, Tyumen, International conference

  [Invited]

  Invited oral presentation


• Basic and Advanced technique of bypass surgery in cerebrovascular disease

  Hidehito Kimura, Eiji Kohmura

  International ediucational course: cerebral revascularization with hands-on workshop in microvascular anastomosis, Feb. 2019, English, Tyumen, International conference

  [Invited]

  Invited oral presentation


• Significance of extracranial- intracranial high flow bypass with trapping for ruptured ICA anterior wall aneurysms in the super-acute phase

  Hidehito Kimura, Eiji Kohmura

  WFNS Fundation ACNS Live Seminar, Dec. 2018, English, タシュケント, International conference

  Oral presentation


• Clinical significance of our original CFD analysis for cerebral aneurysms -What does CFD tell us ?-

  Hidehito Kimura, Eiji Kohmura

  WFNS Fundation ACNS Live Seminar, Dec. 2018, English, タシュケント, International conference

  Oral presentation


• 脳動脈瘤とCFD解析: CFDによる未破裂脳動脈瘤壁性状可視化の可能性 ー臨床家からの視点ー

  KIMURA HIDEHITO, TANIGUCHI MASAAKI, KOHMURA EIJI

  第77回日本脳神経外科学会学術総会, Oct. 2018, Japanese, 仙台, Domestic conference

  Oral presentation


• 内視鏡下経蝶形骨洞的手術における内頚動脈損傷回避のための取り組み

  NAKAI TOMOAKI, TANIGUCHI MASAAKI, KOHTA MASAAKI, UOZUMI YOICHI, KIMURA HIDEHITO, KOHMURA EIJI

  第25回日本神経内視鏡学会, Oct. 2018, Japanese, 新潟, Domestic conference

  Oral presentation


• 斜台下部病変に対する経鼻内視鏡下手術における下鼻甲介粘膜下骨切除の有用性について

  UOZUMI YOICHI, TANIGUCHI MASAAKI, NAKAI TOMOAKI, KOHTA MASAAKI, KIMURA HIDEHITO, KOHMURA EIJI

  第25回日本神経内視鏡学会, Oct. 2018, Japanese, 新潟, Domestic conference

  Oral presentation


• 視機能障害で発症した鞍部・傍鞍部炎症性疾患に対する経鼻内視鏡手術成績

  UOZUMI YOICHI, TANIGUCHI MASAAKI, NAKAI TOMOAKI, KOHTA MASAAKI, KIMURA HIDEHITO, KOHMURA EIJI

  日本脳神経外科学会 第77回学術総会, Oct. 2018, Japanese, 仙台, Domestic conference

  Oral presentation


• 交通性水頭症を合併する聴神経鞘腫におけるADCを用いた腫瘍摘出術後の水頭症改善予測

  NAKAI TOMOAKI, TANIGUCHI MASAAKI, KOHTA MASAAKI, UOZUMI YOICHI, KIMURA HIDEHITO, KOHMURA EIJI

  日本脳神経外科学会第77回学術総会, Oct. 2018, Japanese, 仙台, Domestic conference

  Oral presentation


• 各高位における内頚動脈走行を考慮した経鼻内視鏡頭蓋底手術

  TANIGUCHI MASAAKI, NAKAI TOMOAKI, UOZUMI YOICHI, KIMURA HIDEHITO, KOHMURA EIJI

  日本脳神経外科学会第77回学術総会, Oct. 2018, Japanese, 仙台, Domestic conference

  Public symposium


• 4K3D Video Microexoscope ORBEYEを用いた脳神経外科手術の初期経験

  KIMURA HIDEHITO, TANIGUCHI MASAAKI, NAKAI TOMOAKI, UOZUMI YOICHI, KOHMURA EIJI

  第25回日本神経内視鏡学会, Oct. 2018, Japanese, 新潟, Domestic conference

  Oral presentation


• 3D経鼻内視鏡下手術の利点と欠点

  TANIGUCHI MASAAKI, NAKAI TOMOAKI, UOZUMI YOICHI, KIMURA HIDEHITO, KOHMURA EIJI

  第25回日本神経内視鏡学会, Oct. 2018, Japanese, 新潟, Domestic conference

  Public symposium


• 内頚動脈が関与する頭蓋底腫瘍に対する経鼻内視鏡下手術のリスクマネージメント

  TANIGUCHI MASAAKI, NAKAI TOMOAKI, KIMURA HIDEHITO, KOHMURA EIJI

  第23回日本脳腫瘍の外科学会, Sep. 2018, Japanese, 和歌山, Domestic conference

  Public symposium


• 当院における聴器癌に対する側頭骨亜全摘術の手術手技と治療成績-脳神経外科からの視点 –

  KIMURA HIDEHITO, TANIGUCHI MASAAKI, SHINOMIYA HIROTAKA, TESHIMA MASANORI, NIBU KENICHI, KOHMURA EIJI

  第30回日本頭蓋底外科学会, Jul. 2018, Japanese, 東京, Domestic conference

  Oral presentation


• 経鼻内視鏡下経翼口蓋窩アプローチの臨床解剖

  TANIGUCHI MASAAKI, NAKAI TOMOAKI, KIMURA HIDEHITO, KOHMURA EIJI

  第30回日本頭蓋底外科学会, Jul. 2018, Japanese, 横浜, Domestic conference

  Public symposium


• 当科における頭蓋底進展眼窩悪性腫瘍の検討

  TESHIMA MASANORI, SHINOMIYA HIROTAKA, OTSUKI NAOKI, KIMURA HIDEHITO, TANIGUCHI MASAAKI, HASHIKAWA KAZUNOBU, KOHMURA EIJI, NIBU KENICHI

  第３０回日本頭蓋底外科学会, Jun. 2018, Japanese, 東京, Domestic conference

  Oral presentation


• 当科における頭蓋底進展眼窩悪性腫瘍の検討

  TESHIMA MASANORI, SHINOMIYA HIROTAKA, OTSUKI NAOKI, KIMURA HIDEHITO, TANIGUCHI MASAAKI, HASHIKAWA KAZUNOBU, KOHMURA EIJI, NIBU KENICHI

  第４２回日本頭頸部癌学会, Jun. 2018, Japanese, 東京, Domestic conference

  Oral presentation


• 破裂内頚動脈前壁動脈瘤に対する 緊急頭蓋内外 high flow bypass後トラッピング術：意義と問題

  KIMURA HIDEHITO, TANIGUCHI MASAAKI, KOHMURA EIJI

  第27回脳神経外科手術と機器学会CNTT 2018, Apr. 2018, Japanese, 奈良, Domestic conference

  Oral presentation


• Significance of extracranial- intracranial high flow bypass with trapping for ruptured ICA anterior wall aneurysms in the super-acute phase

  Hidehito Kimura, Eiji Kohmura

  2018 China-Japan Cerebrovascular disease forum, Apr. 2018, English, 東京, International conference

  Oral presentation


• CFDによる未破裂脳動脈瘤壁性状“見える化”の可能性

  Kimura Hidehito, Taniguchi Masaaki, Kohmura Eiji

  第41回日本脳神経CI学会総会, Mar. 2018, Japanese, 日本脳神経CI学会, 新潟, Domestic conference

  Oral presentation


• 海綿静脈洞進展下垂体腺腫摘出における内頚動脈蛇行の影響について

  Taniguchi Masaaki, Nakai Tomoaki, Kimura Hidehito, Kohmura Eiji

  第28回日本間脳下垂体腫瘍学会, Feb. 2018, Japanese, 日本間脳下垂体腫瘍学会, 浜松, Domestic conference

  Oral presentation


• How to dissect the sylvian fissure & preserve important neurovascular structurein the pterional approach

  Kimura Hidehito, Kohmura Eiji

  Premier FUJITA-BANBUNTANE 4th Winter Seminar, Feb. 2018, English, BANBUNTANE HOUTOKUKAI HOSPITAL, 名古屋, International conference

  [Invited]

  Invited oral presentation


• BASIC TECHNIQUE OF MICROANASTOMOSIS IN VASCULAR NEUROSURGERY

  Kimura Hidehito, Kohmura Eiji

  Microvascular anastomosis workshop, Feb. 2018, English, Association of neurosurgeons of the Tyumen Region, Tyumen, Russia, International conference

  [Invited]

  Invited oral presentation


• Anterior clinoidectomy for cerebrovascular lesion

  Kimura Hidehito, Kohmura Eiji

  Premier FUJITA-BANBUNTANE 4th Winter Seminar, Feb. 2018, English, BANBUNTANE HOUTOKUKAI HOSPITAL, 名古屋, International conference

  [Invited]

  Invited oral presentation


• Long-Term Survival of Carotid Endarterectomy and Carotid Artery Stenting in Japanese Population

  Hosoda Kokichi, Fujita Atsushi, Masaaki Kohta, Kimura Hidehito, Taichiro Imahori, Jun Tanaka, Kohmura Eiji

  International Stroke Conference 2018, Jan. 2018, English, American Heart Association, Los Angeles, USA, Introduction: According to the current guidelines, treatment for carotid stenosis with carotid endarterectomy (CEA) or carotid artery stenting (CAS) should be limited to patients with life expectancy of >3 to 5 years. We aimed to assess the long-term surv, International conference

  Poster presentation


• 3Dおよび4K内視鏡を併用した経鼻頭蓋底手術

  Taniguchi Masaaki, Nakai Tomoaki, Kimura Hidehito, Kohmura Eiji

  日本神経内視鏡学会, Nov. 2017, Japanese, 日本神経内視鏡学会, 横浜, Domestic conference

  Public symposium


• 頸動脈病変治療におけるトラブルシューティングとリスク回避

  Hosoda Kokichi, Kota Masaaki, Kimura Hidehito, Fujita Atsushi, 田中 潤, Nakai Tomoaki, 松尾 和哉, Kohmura Eiji

  日本脳神経外科学会第 76 回学術総会, Oct. 2017, Japanese, 日本脳神経外科学会, 名古屋, 【目的】頸動脈疾患・損傷に対する治療はCEA/CASをはじめとして基本的な手技であるが, トラブルに遭遇すると悲惨な結果となることもある. 当施設の経験をもとに, そのような事態を回避する方法やその予防を検討した.【方法】過去10年間の頸動脈疾患の治療経験 (CEA 188, CAS 127, 頸動脈再建 3など) からトラブルシューティングが必要であった代表症例の術中動画を検討し安全な対策や予防の確立を試みた.【結果】(1) 高度の石灰化症例の動脈遮断：総頸動脈が高度に石灰化している, Domestic conference

  Public symposium


• 頭蓋底脊索腫に対する集学的治療の中・長期成績

  Taniguchi Masaaki, Nakai Tomoaki, Kimura Hidehito, Kohmura Eiji

  一般社団法人日本脳神経外科学会第76回学術総会, Oct. 2017, Japanese, 日本脳神経外科学会, 名古屋, Domestic conference

  Oral presentation


• 手術解剖に基づいた傍正中部頭蓋底病変への経鼻内視鏡下アプローチ

  Taniguchi Masaaki, Nakai Tomoaki, Kota Masaaki, Kimura Hidehito, Kohmura Eiji

  一般社団法人日本脳神経外科学会第76回学術総会, Oct. 2017, Japanese, 日本脳神経外科学会, 名古屋, Domestic conference

  [Invited]

  Nominated symposium


• 急性期バイパス併用手術における大伏在静脈グラフトの有用性と取り扱い

  Kimura Hidehito, Taniguchi Masaaki, Hosoda Kokichi, Kohmura Eiji

  第76回日本脳神経外科学会学術総会, Oct. 2017, Japanese, 日本脳神経外科学会, 名古屋, Domestic conference

  Oral presentation


• The endoscopic endonasal “micro” surgery for deep intradural pathology

  Taniguchi Masaaki, Nakai Tomoaki, Kimura Hidehito, Kohmura Eiji

  EANS2017, Oct. 2017, English, Eropean association of neurological surgery, Venezia, Italy, International conference

  Oral presentation


• Surgical techniques for uncommon aneurysms

  Kimura Hidehito, Kohmura Eiji

  13th International conference on Cerebrovascular Surgery, Oct. 2017, English, International conference on Cerebrovascular Surgery, 名古屋, Domestic conference

  Oral presentation


• Operative technique of STA-MCA anastomosis Hidehito Kimura

  Kimura Hidehito, Kohmura Eiji

  13th International conference on Cerebrovascular Surgery, Oct. 2017, English, International conference on Cerebrovascular Surgery, 名古屋, Domestic conference

  Oral presentation


• CFDはクリッピング術者に有益な情報を伝えるか?- 未破裂脳動脈瘤壁の性状可視化の可能性-

  Kimura Hidehito, Taniguchi Masaaki, Kohmura Eiji

  第22回関西脳神経外科手術研究会, Oct. 2017, Japanese, CLSベーリング株式会社, 大阪, Domestic conference

  Oral presentation


• Anatomical and clinical significance of carotico-clinoid ligament from the perspective of endoscopic endonasal surgery

  Nakai Tomoaki, Taniguchi Masaaki, Kimura Hidehito, Kohmura Eiji

  EANS2017, the 17th European Congress of Neurosurgery, Oct. 2017, English, The European Association of Neurosurgical Societies (EANS), Venice, Italy, During the microscopic skull base surgery, especially when approaching the clinoid segment of internal carotid artery (ICA), the carotico-clinoid ligament (CCL), which connects the anterior and middle clinoid process, is sometimes focused on because of it, International conference

  Oral presentation


• 病変高位に応じた各アプローチによる斜台部への経鼻内視鏡手術

  Taniguchi Masaaki, Nakai Tomoaki, Kimura Hidehito, Kohmura Eiji

  第22回日本脳腫瘍の外科学会, Sep. 2017, Japanese, 日本脳腫瘍の外科学会, 鹿児島, Domestic conference

  [Invited]

  Nominated symposium


• 経鼻内視鏡下手術および重粒子線照射で治療した斜台脊索腫の晩期髄液漏について

  Taniguchi Masaaki, Nakai Tomoaki, Kimura Hidehito, Kohmura Eiji

  The 76th Annual meeting of the Japan Neurosurgical society, Sep. 2017, Japanese, the Japan Neurosurgical society, 名古屋, Domestic conference

  Oral presentation


• Behandlungsstrategie von Clivuschordomen mit wiederholter endonasaler Resektion und selektiver Schwerionenbestrahlung

  Taniguchi Masaaki, Nakai Tomoaki, Kimura Hidehito, Kohmura Eiji

  25th German skull base society, Sep. 2017, English, German skull base society, Heidelberg, Germany, International conference

  Oral presentation


• Anatomische Definition der individuelle endoskopische endonasale Zugänge zur oberen, mittleren und unteren para-clivus Läsionen.

  Taniguchi Masaaki, Youichi Uozumi, Nakai Tomoaki, Kimura Hidehito, Kohmura Eiji

  25. Jahrestagung der Deutschen Gesellschaft für Schädelbasischirurgie, Sep. 2017, English, Deutschen Gesellschaft für Schädelbasischirurgie, Heidelberg, Germany, International conference

  Oral presentation


• Prediction of Cerebral Aneurysm Growth using Our Novel Computational Fluid Dynamics Tool

  Kimura Hidehito, Kohsuke Hayashi, Hosoda Kokichi, Fujita Atsushi, Taniguchi Masaaki, Akio Tomiyama, Kohmura Eiji

  第32回日本脳神経外科国際学会フォーラム, Jul. 2017, English, 日本脳神経外科同時通訳団, 大宮, Domestic conference

  Oral presentation


• 当院の経鼻内視鏡下手術による脊索腫の中期治療成績について

  Taniguchi Masaaki, Nakai Tomoaki, Kimura Hidehito, Kohmura Eiji

  The 29th Annual meeting of Japanese Society for skull base surgery, Jun. 2017, Japanese, Japanese Society for skull base surgery, 松本, Domestic conference

  Oral presentation


• 診断に苦慮する稀な頭蓋底溶骨性病変 Central skull base osteomyelitisが疑われた症例

  Kimura Hidehito, Taniguchi Masaaki, Nakai Tomoaki, Kohmura Eiji

  第29回日本頭底外科学会, Jun. 2017, Japanese, 日本頭底外科学会, 松本, Domestic conference

  Oral presentation


• 3T-術中MRI支援下経鼻内視鏡下手術の有用性と問題点について

  Taniguchi Masaaki, Nakai Tomoaki, Kota Masaaki, Kimura Hidehito, 藤田 祐一, Kohmura Eiji

  第29回日本頭蓋底外科学会, Jun. 2017, Japanese, 日本頭蓋底外科学会, 松本, Domestic conference

  Oral presentation


• 頭蓋底腫瘍に対する経鼻内視鏡・開頭手術を組み合わせた計画的二期的手術

  Taniguchi Masaaki, Kimura Hidehito, Nakai Tomoaki, Kohmura Eiji

  第26回脳神経外科手術と機器学会（CNTT）学術総会, Apr. 2017, Japanese, 脳神経外科手術と機器学会（CNTT）, 山梨, Domestic conference

  Public symposium


• Effective use of deep temporal fat pad for skull base reconstruction

  Kimura Hidehito, Taniguchi Masaaki, Kohmura Eiji

  CNTT2017, Apr. 2017, Japanese, 日本脳神経外科手術と機器学会, 甲府, Domestic conference

  Oral presentation


• Unanticipated complication and its management in the direct surgery for paraclinoid aneurysms.

  Kimura Hidehito, Kohmura Eiji

  INTERNATIONAL CONFERENCE ON COMPLICATIONS IN NEUROSURGERY, Mar. 2017, English, INTERNATIONAL CONFERENCE ON COMPLICATIONS IN NEUROSURGERY, India, Mumbai, International conference

  [Invited]

  Invited oral presentation


• Treatment strategy for A ruptured giant internal carotid artery aneurysm

  Kimura Hidehito, Kohmura Eiji

  INTERNATIONAL CONFERENCE ON COMPLICATIONS IN NEUROSURGERY, Mar. 2017, English, INTERNATIONAL CONFERENCE ON COMPLICATIONS IN NEUROSURGERY, India, Mumbai, International conference

  [Invited]

  Invited oral presentation


• Prediction of cerebral aneurysm enlargement using MR-based computational fluid dynamics

  Kimura Hidehito, 林 公祐, Hosoda Kokichi, Fujita Atsushi, 冨山 明男, Kohmura Eiji

  Stroke 2017, Mar. 2017, Japanese, 日本脳卒中の外科学会, 大阪, Domestic conference

  Oral presentation


• Prediction of Cerebral Aneurysm Growth Using Novel Magnetic Resonance Imaging-based Computational Fluid Dynamics Tool

  Kimura Hidehito, Kohsuke Hayashi, Hosoda Kokichi, Fujita Atsushi, Taniguchi Masaaki, Akio Tomiyama, Kohmura Eiji

  International stroke conference 2017, Feb. 2017, English, American Heart Association & American Stroke Association, Houston, America, International conference

  Poster presentation


• How can we manage:A ruptured giant internal carotid artery aneurysm

  Kimura Hidehito, Taniguchi Masaaki, Kohmura Eiji

  第3回世界低侵襲脳神経外科学会 教育学会(ISIMINS), Feb. 2017, English, 世界低侵襲脳神経外科学会, 品川, International conference

  Oral presentation


• Extracranial-intracranial bypass - basics and advances -

  Kimura Hidehito, Kohmura Eiji

  Microvascular anastomosis workshop, Feb. 2017, English, Association of neurosurgeons of the Tyumen Region, Tyumen, Russia, International conference

  [Invited]

  Invited oral presentation


• Anterior clinoidectomy

  Kimura Hidehito, Kohmura Eiji

  Premier FUJITA-BANBUNTANE 3nd Winter Seminar, Jan. 2017, English, BANBUNTANE HOUTOKUKAI HOSPITAL, 名古屋, International conference

  [Invited]

  Invited oral presentation


• Technical considerations for safer and reliable direct surgery for paraclinoid aneurysms

  Kimura Hidehito, Kohmura Eiji

  International Educational Course Skull Base Surgery, Oct. 2016, English, Asian Congress of Neurological Surgeons, Tyumen, Russia, International conference

  [Invited]

  Invited oral presentation


• Anterior petrosal approach

  Kimura Hidehito, Kohmura Eiji

  International Educational Course Skull Base Surgery, Oct. 2016, English, Asian Congress of Neurological Surgeons, Tyumen, Russia, International conference

  [Invited]

  Invited oral presentation


• 傍前床突起部動脈瘤直達術のpitfallとrecovery

  Kimura Hidehito, Taniguchi Masaaki, Hosoda Kokichi, Kohmura Eiji

  第75回日本脳神経外科学会学術総会, Sep. 2016, Japanese, 日本脳神経外科学会, 福岡, Domestic conference

  Oral presentation


• 蝶形骨洞内に再発した頭蓋咽頭腫3例

  藤田 祐一, Taniguchi Masaaki, Nakai Tomoaki, Kimura Hidehito, Mizukawa Katsu, Kohmura Eiji

  第72回日本脳神経外科学会近畿支部学術集会, Sep. 2016, Japanese, 日本脳神経外科学会, 大阪, Domestic conference

  Oral presentation


• Clinical Significance of the Tumor ADC Map in Vestibular Schwannomas with Communicating Hydrocephalus

  Nakai Tomoaki, Kimura Hidehito, Taniguchi Masaaki, Kohmura Eiji

  日本脳神経外科学会第75回学術総会, Sep. 2016, Japanese, 日本脳神経外科学会, 福岡, 【目的】交通性水頭症を併発した聴神経鞘腫について、術後経過や腫瘍の特徴を解析し、水頭症合併の要因を考察した。【対象、方法】当科にて2008年1月より2015年5月までの7年5か月間で、手術加療を行なった聴神経鞘腫146症例を後方視的に調査した。閉塞性水頭症の関与を避けるため、大型腫瘍を除いたMax CPA 30mm以下の腫瘍に着目すると77症例あり、このうち9例に交通性水頭症の合併がみられた。なお、再発や放射線加療施行後、NF-2症例などは除外した。年齢や腫瘍サイズ、病理学的検査、術後経過などとともに、充実性腫瘍のADC（apparent diffusion coefficient）値を、交通性水頭症の有無で比較し、水頭症合併に関与する因子を検討した。【結果】交通性水頭症合併症例においては、腫瘍の摘出により、全例で水頭症症状および画像上の脳室拡大の改, Domestic conference

  Oral presentation


• Countermeasures against congenital toxoplasmosis and cytomegalovirus infection led by the research team under the supervision of the Ministry of Health, Labor and Welfare in Japan.

  Fujii T, Ikeda T, Inoue N, Kanayama N, Kawana T, Kimura Hidehito, Kobayashi Y, Koyano S, Masuzaki H, Matsuyama H, Minematsu T, Morioka Ichiro, Moriuchi H, Oka A, Saito S, Samejima H, Suzutani T, Yamada Hideto, Yoshikawa Takeshi

  CMV Public Health & Policy Conference, Sep. 2016, English, CMV Public Health & Policy Conference, Austin, USA, International conference

  Oral presentation


• CEA/CAS による相補的な治療に おける高難度症例の治療と成績

  Hosoda Kokichi, Fujita Atsushi, Kota Masaaki, 田中 潤, 山本 祐輔, Kimura Hidehito, Nakai Tomoaki, Kohmura Eiji

  日本脳神経外科学会第 75 回学術総会, Sep. 2016, Japanese, 日本脳神経外科学会, 福岡, Domestic conference

  Public symposium


• ナビゲータ・術中MRIを併用した経鼻内視鏡下手術

  Taniguchi Masaaki, Kota Masaaki, Kimura Hidehito, Kohmura Eiji

  第31回日本脳神経外科国際学会フォーラム, Jul. 2016, Japanese, 日本脳神経外科同時通訳団, 福岡, Domestic conference

  [Invited]

  Invited oral presentation


• Technical considerations for safer and reliable direct surgery for paraclinoid aneurysms

  Kimura Hidehito, Taniguchi Masaaki, Hosoda Kokichi, Kohmura Eiji

  第31回日本脳神経外科国際学会フォーラム, Jul. 2016, English, 日本脳神経外科同時通訳団, 福岡, Domestic conference

  Oral presentation


• Microvascular anastomosis training using a chicken wing

  Kimura Hidehito, Kohmura Eiji

  2016 China – Japan Cerebral vascular disease Forum, Jul. 2016, English, Renji Hosptital, Shanghai, China, International conference

  Public discourse


• How to perform safe and reliable extracranial-intracranial bypass

  Kimura Hidehito, Kohmura Eiji

  2016 China – Japan Cerebral vascular disease Forum, Jul. 2016, English, China Executive Leadership Academy, Shanghai, China, International conference

  [Invited]

  Invited oral presentation


• 頸動脈狭窄症に対する CEA と CAS の相補的な適応選択とそ の成績

  Hosoda Kokichi, Fujita Atsushi, Kota Masaaki, 今堀 太一郎, Kimura Hidehito, 山本 祐輔, 田中 潤, Nakai Tomoaki, Kohmura Eiji

  第3回日本心血管脳卒中学会学術集会, Jun. 2016, Japanese, 日本心血管脳卒中学会, 品川, Domestic conference

  [Invited]

  Nominated symposium


• Technical considerations for safer and reliable direct surgery for paraclinoid aneurysms

  Kimura Hidehito, Taniguchi Masaaki, Hosoda Kokichi, Kohmura Eiji

  7th International Congress of the World Federation of the skull base Societies28th Annual Meeting of Japanese of Skull Base Surgery, Jun. 2016, English, 日本頭蓋底外科学会, 大阪, International conference

  Oral presentation


• Distinct endoscopic endonasal approaches to paraclival skull base lesions

  Taniguchi Masaaki, Kimura Hidehito, Kohmura Eiji

  7th International Congress of the World Federation of Skull Base Societies, Jun. 2016, English, 日本頭蓋底外科学会, 大阪, International conference

  [Invited]

  Nominated symposium


• Communicating Hydrocephalus associated with small to medium sized Vestibular Schwannomas: Clinical Significance of the tumor ADC map

  Nakai Tomoaki, Taniguchi Masaaki, Kimura Hidehito, Kohmura Eiji

  7th International Congress of World Federation of Skull Base Societies, Jun. 2016, English, the World Federation of Skull Base Society, 大阪, Object: The postoperative temporal change of the hydrocephalus associated with the small to medium sized vestibular schwannoma was studied and tumor-specific factors related to the association of the hydrocephalus were investigated.Methods: Among the 77 p, International conference

  Poster presentation


• The technical tips for intracranial revascularization

  Kimura Hidehito, Hosoda Kokichi, Kohmura Eiji

  Stroke 2016, Apr. 2016, Japanese, 日本脳卒中の外科学会, 札幌, Domestic conference

  Oral presentation


• 高齢者の頚動脈狭窄症に対する治療成績からみた周術期管理の留意点の検討

  Kota Masaaki, Hosoda Kokichi, Fujita Atsushi, 今堀 太一郎, 山本 祐輔, 田中 潤, Kimura Hidehito, Kohmura Eiji

  第45回 日本脳卒中の外科学会学術集会, Apr. 2016, Japanese, 脳卒中の外科学会, 札幌, Domestic conference

  Oral presentation


• Technical tips in comtemporary skull base surgeries

  Kimura Hidehito, Kohmura Eiji

  The 7th Internatiaonal Mt. BANDAI Symposium for Neuroscience & The 8the Pan-Pancific Neurosurgery Congress, Apr. 2016, English, Pan-Pacific Neurosurgery Congress, Phnom Penh, Cambodia, International conference

  [Invited]

  Invited oral presentation


• Prediction of cerebral aneurysm enlargement using MR-based computational fluid dynamics

  Kimura Hidehito, 林 公祐, Hosoda Kokichi, Fujita Atsushi, 冨山 明男, Kohmura Eiji

  Stroke 2016, Apr. 2016, Japanese, 日本脳卒中の外科学会, 札幌, Domestic conference

  Poster presentation


• Microvascular anastomosis training using artificial blood vessel

  Kimura Hidehito, Kohmura Eiji

  The 7th Internatiaonal Mt. BANDAI Symposium for Neuroscience & The 8the Pan-Pancific Neurosurgery Congress, Apr. 2016, English, Pan-Pacific Neurosurgery Congress, Phnom Penh, Cambodia, International conference

  [Invited]

  Invited oral presentation


• 頭蓋内外血行再建における大伏在静脈の功罪

  Kimura Hidehito, Taniguchi Masaaki, Kohmura Eiji

  第25回脳神経外科手術と機器学会, Mar. 2016, Japanese, 脳神経外科手術と機器学会, 新潟, Domestic conference

  Oral presentation


• 経鼻内視鏡下手術における術野確保のための鼻腔内処置

  Taniguchi Masaaki, Kimura Hidehito, Kohmura Eiji

  第25回脳神経外科手術と機器学会, Mar. 2016, Japanese, 脳神経外科手術と機器学会, 新潟, Domestic conference

  Oral presentation


• Essential Technical Tips in Contemporary Skull Base Surgeries

  Kimura Hidehito

  The 11th Asian Congress of Neurological Surgeons 2016 in conjunction with The 21th Annual Scientific Meeting of Indonesian Society of Neurological Surgeons, Mar. 2016, English, Surabaya, Indonesia, International conference

  Oral presentation


• Long-term Outcomes of Carotid Endarterectomy and Carotid Artery Stenting : Real-World Status of Single Institute in Japan

  Hosoda Kokichi, Taichiro Imahori, Fujita Atsushi, Yusuke Yamamoto, Kimura Hidehito, Masaaki Kohta, Kohmura Eiji

  INTERNATIONAL STROKE 2016 CONFERENCE, Feb. 2016, Japanese, LosAngeles, USA, International conference

  Oral presentation


• Long-term outcomes of carotid endarterectomy and carotid artery stenting: real-world status of single institute in japan

  Hosoda Kokichi, Imahori T, Fujita Atsushi, Yamamoto Yasuji, Kimura Hidehito, Kota Masaaki, Kohmura Eiji

  International Stroke Conference 2016, Feb. 2016, English, American Heart Association, American Stroke Association, Los Angeles, USA, International conference

  Poster presentation


• How to dissect the sylvian fissure & preserve important neurovascular structurein the pterional approach

  Kimura Hidehito, Kohmura Eiji

  Premier FUJITA-BANBUNTANE 2nd Winter Seminar, Jan. 2016, English, 藤田保健衛生大学坂文種報德會病院, 名古屋, Domestic conference

  [Invited]

  Invited oral presentation


• 海綿静脈洞から頭蓋内外進展を来した再発頭蓋底髄膜腫の1例

  Kimura Hidehito, Taniguchi Masaaki, Kohmura Eiji

  第20回関西脳神経外科手術研究会, Dec. 2015, Japanese, 関西脳神経外科手術研究会, 大阪, Domestic conference

  Oral presentation


• 内視鏡導入後の脊索腫・軟骨肉腫の中期治療成績

  Taniguchi Masaaki, 阿久津 宣之, Mizukawa Katsu, Kimura Hidehito, 相原 英夫, Kohmura Eiji

  第22回日本神経内視鏡学会, Nov. 2015, Japanese, 日本内視鏡学会, 松島, Domestic conference

  Public symposium


• 神経内視鏡支援動脈瘤手術の課題と対策

  Kimura Hidehito

  第22回日本神経内視鏡学会, Nov. 2015, Japanese, 日本内視鏡学会, 松島, Domestic conference

  Public symposium


• 傍斜台部病変に対する経鼻内視鏡下手術 ―各病変首座に応じた進入経路の選択―

  Taniguchi Masaaki, Mizukawa Katsu, Kimura Hidehito, Kota Masaaki, Kohmura Eiji

  一般社団法人・日本脳神経外科学会第74回学術総会, Oct. 2015, Japanese, 日本脳神経外科学会, 札幌, Domestic conference

  Oral presentation


• 自施設の短期及び長期治療成績と文献資料に基づく頸動脈狭窄症の治 療戦略

  Hosoda Kokichi, Fujita Atsushi, Kota Masaaki, 今堀 太一郎, 山本 祐輔, 田中 潤, Kimura Hidehito, Kohmura Eiji

  日本脳神経外科学会 第74回学術総会, Oct. 2015, Japanese, 日本脳神経外科学会, 札幌, Domestic conference

  Oral presentation


• より安全で簡便な傍前床突起部動脈瘤直達術の考察

  Kimura Hidehito, Hosoda Kokichi, Kohmura Eiji

  第74回日本脳神経外科学会学術集会, Oct. 2015, Japanese, 日本脳神経外科学会学会, 北海道, Domestic conference

  Oral presentation


• Microvascular anastomosis trainingusing artificial blood vessel for STA-MCA, STA-SCA bypass

  Kimura Hidehito, Kohmura Eiji

  4th Nepal Japan Neurosurgical Conference 3rd National Meeting of NESON (Nepalese Society of Neurosurgeons, Oct. 2015, English, Nepalese Society of Neurosurgeons, カトマンヅ, ネパール, International conference

  [Invited]

  Invited oral presentation


• Essential technical tips in skull base surgeries

  Kimura Hidehito, Kohmura Eiji

  4th Nepal Japan Neurosurgical Conference 3rd National Meeting of NESON (Nepalese Society of Neurosurgeons, Oct. 2015, English, Nepalese Society of Neurosurgeons, カトマンヅ, ネパール, International conference

  [Invited]

  Invited oral presentation


• Clinical application of skull base surgery for cerebrovascular lesion

  Kimura Hidehito, Kohmura Eiji

  China – Japan Neurosurgical Skull Base and Cerebral vascular disease Forum, Oct. 2015, English, China – Japan Neurosurgical Skull Base and Cerebral vascular disease Forum, 上海, 中国, International conference

  [Invited]

  Invited oral presentation


• 当科における経鼻内視鏡頭蓋底手術の現状

  Taniguchi Masaaki, 阿久津 宣行, Kimura Hidehito, Inokuchi Gou, Kohmura Eiji

  第20回日本脳腫瘍の外科学会, Sep. 2015, Japanese, 日本脳腫瘍の外科学会, 名古屋, Domestic conference

  Public symposium


• Long-term outcomes of carotid endarterectomy and carotid artery stenting for carotid artery stenosis: real-world status in japan

  Hosoda Kokichi, Imahori T, Fujita Atsushi, Yamamoto Yasuji, Mizowaki T, Miyake S, Kimura Hidehito, Kota Masaaki, Kohmura Eiji

  15th INTERIM MEETINGOF THE WORLD FEDERATIONOF NEUROSURGICAL SOCIETIES, Sep. 2015, English, THE WORLD FEDERATIONOF NEUROSURGICAL SOCIETIES, Rome, Italy, International conference

  Oral presentation


• Long-term outcome of carotid endarterectomy and carotid artery stenting for carotid artery stenosis in octogenarians: real- world status in Japan

  Taichiro Imahori, Hosoda Kokichi, Fujita Atsushi, Yusuke Yamamoto, Tomoaki Nakai, Shigeru Miyake, Kimura Hidehito, Masaaki Kohta, Kohmura Eiji

  15th INTERIM MEETINGOF THE WORLD FEDERATIONOF NEUROSURGICAL SOCIETIES, Sep. 2015, English, THE WORLD FEDERATIONOF NEUROSURGICAL SOCIETIES, Rome, Italy, International conference

  Poster presentation


• Endoscopic endonasal trans-lacerum approach to the inferior petrous apex

  Taniguchi Masaaki, Nobuyuki Akutsu, Mizukawa Katsu, Masaaki Kohta, Kimura Hidehito, Kohmura Eiji

  15th WFNS Interim Meeting, Sep. 2015, English, THE WORLD FEDERATIONOF NEUROSURGICAL SOCIETIES, ローマ, イタリア, International conference

  Oral presentation


• Distinct approaching routes to para-median skull base lesions in the endoscopic endonasal surgery.

  Taniguchi Masaaki, 阿久津 宣行, Mizukawa Katsu, Inokuchi Gou, Kimura Hidehito, Nibu Ken-ichi, Kohmura Eiji

  第27回日本頭蓋底外科学会, Jul. 2015, Japanese, 日本頭蓋底外科学会, 名古屋, Domestic conference

  Public symposium


• 当院における頚動脈狭窄症に対する血行再建術（CEA/CAS）の中長期成績と周術期抗血栓療法

  Kota Masaaki, Hosoda Kokichi, 今堀 太一郎, Fujita Atsushi, 山本 祐輔, Kimura Hidehito, Kohmura Eiji

  第45回兵庫県脳神経外科医懇話会, Jul. 2015, Japanese, 兵庫県脳神経外科懇話会, 神戸, Domestic conference

  Keynote oral presentation


• Technical consideration for safe and feasible revascularization procedure for SCA & PCA

  Kimura Hidehito, Taniguchi Masaaki, Kohmura Eiji

  第30回日本脳神経外科国際学会フォーラム, Jul. 2015, English, 日本脳神経外科同時通訳団, 兵庫, Domestic conference

  Oral presentation


• PCAバイパスのためのMinimum Transpetrosal Approach

  Kimura Hidehito, Taniguchi Masaaki, Kohmura Eiji

  第27回日本頭蓋底外科学会, Jul. 2015, Japanese, 日本頭蓋底外科学会, 名古屋, Domestic conference

  Oral presentation


• Postoperative complications in skull base surgery for nasal and paranasal malignant tumors involving skull base

  手島 直則, 四宮 弘隆, Ohtsuki Naoki, Kimura Hidehito, Hashikawa Kazunobu, Kohmura Eiji, Nibu Ken-ichi

  The Joint Meeting of 4th Congress of Asian Society of Head and Neck Oncology (ASHNO) and 39th Annual Meeting of Japan Society for Head and Neck Cancer (JSHNC), Jun. 2015, English, Japan Society for Head and Neck Cancer, 神戸, International conference

  Poster presentation


• 80歳以上の高齢者の頚動脈狭窄症に対する血行再建術（CEA/CAS）の長期予後

  今堀 太一郎, Hosoda Kokichi, Fujita Atsushi, 山本 祐輔, 田中 潤, 中井 友昭, Kota Masaaki, Kimura Hidehito, Kohmura Eiji

  第2回日本心血管脳卒中学会学術集会, Jun. 2015, Japanese, 日本心血管脳卒中学会, 徳島, Domestic conference

  Oral presentation


• “Microsurgical” technique during the endosopic endonasal surgery

  Taniguchi Masaaki, 阿久津 宣之, Kimura Hidehito, Kohmura Eiji

  第24回 脳神経外科手術と機器学会, Apr. 2015, Japanese, 脳神経外科手術と機器学会, 大阪, Domestic conference

  Public symposium


• Selection and management of autologous vascular grafts in extracranial-intracranial bypass surgery

  Kimura Hidehito, Taniguchi Masaaki, Kohmura Eiji

  第24回脳神経外科手術と機器学会 (CNTT2015), Apr. 2015, Japanese, 日本脳神経外科手術と機器学会, 大阪, Domestic conference

  Oral presentation


• T2*およびSWIで低信号を呈した小脳原発胚細胞腫の一例

  森 達也, 南 徳明, Tanaka Kazuhiro, Kimura Hidehito, 前山 昌博, Nakamizo Satoshi, 長嶋 宏明, Mizukawa Katsu, Sasayama Takashi, Kohmura Eiji

  第69回日本脳神経外科近畿支部学術集会, Apr. 2015, Japanese, 日本脳神経外科学会, 大阪, Domestic conference

  Oral presentation


• MRAを用いたCFD解析- 脳動脈瘤の増大予測は可能か -

  木村英仁, 林 公佑, 甲村英二

  第44回日本脳卒中の外科学会学術集会 一般演題（優秀ポスター演題）, Mar. 2015

  Poster presentation


• The importance of emergent high flow bypass in treating ruptured blister-like aneurysms

  Kimura Hidehito, Hosoda Kokichi, Kohmura Eiji

  Stroke 2015, Mar. 2015, Japanese, 日本脳卒中学会, 広島, Domestic conference

  Oral presentation


• 頚動脈内膜剥離術 (CEA) と頚動 脈ステント (CAS) の中長期成績

  Hosoda Kokichi, 今堀太一郎, Fujita Atsushi, Kimura Hidehito, Kota Masaaki, Uyama Atsushi, 山本祐輔, Kohmura Eiji

  Stroke 2015, Mar. 2015, Japanese, 日本脳卒中学会, 広島, Domestic conference

  Oral presentation


• Prediction of cerebral aneurysm enlargement using MR-based computational fluid dynamics

  Kimura Hidehito, 林 公祐, Hosoda Kokichi, Fujita Atsushi, 冨山明男, Kohmura Eiji

  Stroke 2015, Mar. 2015, Japanese, 日本脳卒中学会, 広島, Domestic conference

  Poster presentation


• How to dissect the sylvian fissure & preserve important neurovascular structure in the pterional approach

  Kimura Hidehito, Kohmura Eiji

  Premier FUJITA-BANTANE CVD Winter Seminar 2015, Feb. 2015, English, Banbuntane Hospital, 名古屋, Domestic conference

  [Invited]

  Invited oral presentation


• 術中動脈損傷に対するトラブルシューティング -クロス縫合とトランスポジションの有効性-

  Kimura Hidehito, Taniguchi Masaaki, Kohmura Eiji

  第19回関西脳神経外科手術研究会, Dec. 2014, English, 関西脳神経外科手術研究会, 大阪, Domestic conference

  Oral presentation


• Middle and Long-term Outcomes for Carotid Artery Stenosis with CEA or CAS

  今堀太一郎, Hosoda Kokichi, Fujita Atsushi, 山本祐輔, Kimura Hidehito, Kota Masaaki, Uyama Atsushi, Kohmura Eiji

  第30回日本脳神経血管内治療学会総会, Dec. 2014, Japanese, 日本脳神経血管内治療学会, 横浜, Domestic conference

  Oral presentation


• 硬膜外傍正中頭蓋底病変に対する経鼻内視鏡手術 -進入経路の解剖学的・臨床的検討-

  Taniguchi Masaaki, 阿久津宣行, Kota Masaaki, Kimura Hidehito, Kohmura Eiji

  第21回日本神経内視鏡学会, Nov. 2014, Japanese, 日本神経内視鏡学会, 東京, Domestic conference

  Public symposium


• 錐体尖下部・斜台下部外側病変に対する経鼻内視鏡下アプローチ

  Taniguchi Masaaki, 阿久津宣行, Kota Masaaki, Kimura Hidehito, Kohmura Eiji

  日本脳神経外科学会第73回学術総会, Oct. 2014, Japanese, 日本脳神経外科学会, 東京, Domestic conference

  Public symposium


• 頚動脈狭窄症に対する頚動脈内膜 剥離術 (CEA) と頚動脈ステント (CAS) の中長期成績

  Hosoda Kokichi, 今堀太一郎, Fujita Atsushi, Kimura Hidehito, Kota Masaaki, Uyama Atsushi, 山本祐輔, Kohmura Eiji

  日本脳神経外科学会第 73 回学術総会, Oct. 2014, Japanese, 日本脳神経外科学会, 東京, Domestic conference

  Oral presentation


• Technical consideration for safe and reliable revascularization procedure of the superior cerebellar artery and the posterior cerebral artery

  Kimura Hidehito, 岡村 有祐, 小山 淳二, Nakamizo Satoshi, Kohmura Eiji

  第72回日本脳神経外科学会学術総会, Oct. 2014, Japanese, 日本脳神経外科学会, 東京, Domestic conference

  Public symposium


• Essential technical tips in contemporary skull base surgery

  Kimura Hidehito, Kohmura Eiji

  The Second Shuguang International Conference on Neurosurgery, Oct. 2014, English, Shuguang Hosipital, 上海, 中国, International conference

  [Invited]

  Invited oral presentation


• Clinical application of skull base surgery for cerebrovascular lesion

  Kimura Hidehito, Kohmura Eiji

  The 4th ACNS Course, Oct. 2014, English, Asian Congress of Neurological Surgeons, チュメニ, ロシア, International conference

  [Invited]

  Invited oral presentation


• 80歳以上の高齢者頚動脈狭窄症に対する血行再建術(CEA/CAS)の中長期成績

  山本祐輔, Hosoda Kokichi, Fujita Atsushi, 今堀太一郎, 中井友昭, Kimura Hidehito, Kota Masaaki, Uyama Atsushi, Kohmura Eiji

  日本脳神経外科学会第 73 回学術総会, Oct. 2014, Japanese, 日本脳神経外科学会, 東京, Domestic conference

  Oral presentation


• Essential technical tips in contemporary skull base surgery - Learning from cadaver dissection- 1

  Kimura Hidehito, Kohmura Eiji

  10th Asian Congress of Neurological Surgeons, Sep. 2014, English, Asian Congress of Neurological Surgeons, アスタナ, カザフスタン, International conference

  Oral presentation


• 頭蓋咽頭腫に対するBasal interhemispheric trans-lamina terminalis sub-A com approach

  Kimura Hidehito, Taniguchi Masaaki, Kohmura Eiji

  第26回日本頭蓋底外科学会, Jun. 2014, Japanese, 日本頭蓋底外科学会, 千葉, Domestic conference

  Public symposium


• 錐体尖下部・斜台下部外側病変に対する経鼻的内視鏡下手術

  Taniguchi Masaaki, 阿久津宣行, Kota Masaaki, Kimura Hidehito, Kohmura Eiji

  第26回日本頭蓋底外科学会, Jun. 2014, Japanese, 日本頭蓋底外科学会, 千葉, Domestic conference

  Public symposium


• Technical consideration for safe and feasible revascularization procedure of the superior cerebellar artery and the posterior cerebral artery

  Kimura Hidehito, Taniguchi Masaaki, Kohmura Eiji

  11th European Skull Base Society Congress, Jun. 2014, English, European Skull Base Society, パリ, フランス, International conference

  Oral presentation


• Endoscopic endonasal supra-Rosenmueller fossa approach to the inferior petrous apex and jugular tubercle

  Taniguchi Masaaki, Kimura Hidehito, Kohmura Eiji

  11th European Skull Base Society Congress, Jun. 2014, English, European Skull Base Society, パリ, フランス, International conference

  Oral presentation


• traoperative flushing and storage of the saphenous vein graft by using autologous blood

  Kimura Hidehito, Kohmura Eiji

  第23回脳神経外科手術と機器学会, Apr. 2014, Japanese, 脳神経外科手術と機器学会, 福岡, Domestic conference

  Oral presentation


• Status and problems of surgical treatment for asymptomatic carotid stenosis

  Hosoda Kokichi, Fujita Atsushi, Kimura Hidehito, Kota Masaaki, Akutsu Nobuyuki, 今堀 太一郎, 溝脇 卓, 石井 大嗣, Kohmura Eiji

  STROKE2014, Mar. 2014, Japanese, STROKE, 大阪, 【目的】当施設でのCEA/CASの成績を調査し無症候性頚動脈狭窄症に対する治療の現状と課題を検討した。【対象と方法】対象は当施設で7年間に施行した210例（CEA 125、CAS 85）、無症候性121例（CEA 69、CAS 52）、症候性89例（CEA 56、CAS 33）であった。RCTに基づき適応を決定。全麻不可はCASとした。【結果】(1) 無症候性群と症候性群の間で、年齢（70.9 vs 72.7）、男女比（103/18 vs 79/10）、狭窄率（75.1% vs 76.5%）、CEA/CAS比率（69/52 vs 56/33）に有意差なし。(2) 冠動脈疾患と大動脈疾患の罹患率は症候性群の方が高かったが（17% vs 25%）、有意差なし。(3) 無症候性から症候性となった5例はMRIやエコーでsoft plaqueであった。(4), Domestic conference

  Public symposium


• 左内頸動脈-後交通動脈分岐部動脈瘤のneck clipping後に再出血を来した超高齢者の1例

  Okamura Yusuke, 三宅 茂, Kimura Hidehito

  STROKE2014, Mar. 2014, Japanese, STROKE, 大阪, 【はじめに】近年、高齢社会となった日本において、くも膜下出血患者の高齢化も起こっており、その治療適応・方法および時期においても施設間格差のある状況である。今回、我々は左内頸動脈-後交通動脈分岐部動脈瘤のneck clipping後に再出血を来した超高齢者の一例を経験したため報告する。【症例】90歳男性。突然の頭痛にて発症し救急搬送。CTにてくも膜下出血（H&K grade2、WFNS grade2）を認め、3D-CTAにて左内頸動脈-後交通動脈分岐部に径2.7×3.5mm程度の動脈瘤を確認、同日クリッピング術を施行した。術中所見では動脈瘤壁は非常に薄く、一部P-comに伸展を認めるtrunk typeの動脈瘤であった。術後脳血管攣縮予防を行うと共に早期リハビリを開始した。術後8日目に再出血した為、脳血管撮影を施行すると動脈瘤の再増大を認めていた。親動, Domestic conference

  Poster presentation


• 安全な確実なSCAやPCAへのバイパス手術のために

  Kimura Hidehito, Hosoda Kokichi, Kohmura Eiji

  STROKE2014, Mar. 2014, Japanese, STROKE, 大阪, ＜目的＞脳血管障害の外科治療において時に後方循環系へのバイパス術が必要となるが、これらは深部での縫合となり各種の工夫が必要である。今回SCAあるいはPCAをレシピエントとするバイパス術をより安全確実に行うためのポイントを自験例から検討して報告する。＜対象＞対象は2010年5月以降に行ったSCA,PCAをレシピエントとするバイパス術6例 (STA-SCA 4例, STA-PCA 1例,V3-RA-P2 1例)＜手術の要点＞SCAへのバイパス術はsubtemporal approachで行うが、体位はpresigmoid approachへの拡大も考えPark Benchとし頭頂側を充分下げて固定する。中頭蓋底ぎりぎりの開頭を行い、ドリルにて骨の“庇”を除去して中頭蓋底に沿った視軸を確保する。髄液ドレナージを有効に使いながら、側頭葉の圧排はveinof, Domestic conference

  Oral presentation


• 椎骨動脈瘤に対する直達手術の役割と対策

  Kimura Hidehito, Kohmura Eiji

  第18回関西脳神経外科手術研究会, Dec. 2013, Japanese, 関西脳神経外科手術研究会, 大阪, 血管内手術が第一選択の椎骨動脈瘤であるが、直達術を行った自験例から開頭手術の役割と対策を検討。対象は2009年1月以降手術を行った椎骨動脈瘤9例10手術。男性3例、女性7例、平均年齢62.2歳。VA-PICAの動脈瘤が7例（内破裂3例、未破裂3例、症候性1例）椎骨動脈解離による破裂が2例。手術は9例全例transcondylar fossa approachを用いていたが、再手術を要した1例はmidline suboccipital aapproachを用いていた。退院時mRS:0-1が5例、mRS:2,3,4がそれぞれ1例、mRS:6（心筋梗塞合併）が1例あったが、転帰は概ね良好と思われた。椎骨動脈動脈瘤において血行再建を必要とする場合には開頭手術が求められる。そのためOAの剥離、V3の露出などの手術手技にも精通しておく必要がある。手術ビデオを提示, Domestic conference

  Oral presentation


• How to perform, safe & reliable EC-IC bypass

  Kimura Hidehito, Kohmura Eiji

  1st Shuguang International Congress on Neurosurgery meeting, Nov. 2013, English, Shanghai Shuguang hospital, Shanghai, 中国, Vascular reconstruction for complicated cerebral aneurysms is sometimes required in order to prevent ischemic complications. Needless to say, we need to perform safe and reliable bypass. Here I introduce the tips and pitfalls in performing STA- MCA anastomosis, STA-SCA anastomosis, and so-called High Flow bypasses by using saphenous vein graft. And I emphasize the needs for tr, International conference

  [Invited]

  Invited oral presentation


• Clinical application of skull base surgery for cerebrovascular lesion

  Kimura Hidehito, Kohmura Eiji

  1st Shuguang International Congress on Neurosurgery meeting, Nov. 2013, English, Shanghai Shuguang hospital, Shanghai, 中国, Although the recent advancement of endovascular surgery, we still have need to perform craniotomy, especially for complex cerebral aneurysms. In treating such complex ones, we sometimes need to apply skull base techniques, including anterior clinoidectomy, mastoidectomy, condylar drilling. It is well known that anterior clinoidectomy is essential technique for the treatment of, International conference

  [Invited]

  Invited oral presentation


• ハイリスクの頸動脈狭窄症に対する治療の現状と課題

  Hosoda Kokichi, Fujita Atsushi, Kimura Hidehito, Kota Masaaki, Akutsu Nobuyuki, 石井 大嗣, 今堀 太一郎, 溝脇 卓, Kohmura Eiji

  The 72nd Annual Meeting of the Japan Neurosurgical Society, Oct. 2013, Japanese, Annual Meeting of the Japan Neurosurgical Society, 横浜, 【目的】当施設でのCEA/CASの成績を基にハイリスクの頚動脈狭窄症に対する治療の現状と課題を検討した.【対象と方法】対象は6.5年間に施行した196例（CEA115，CAS81）．RCTに基づき外科医と血管内治療医が相談し適応決定．負荷心電図と呼吸機能より全麻不可はCASとした.【結果】(1) 全成績：死亡率 CEA 0, CAS 1/81 (1.2%)．脳梗塞 CEA 3/115 (2.6%), CAS 3/81 (3.7%)．(2) 80歳以上29例 (14.8%) CEA 16 (脳梗塞 1 [6.3%]), CAS 13 (ARDSで死亡 1 [7.7%])．80歳未満 CEA 99 (脳梗塞 2 [2%]), CAS 68 (脳梗塞 3 [4.4%])．有意差なし. (3) 対側内頚動脈閉塞11例 (5.6%) CEA 6, CAS 5, Domestic conference

  Public symposium


• High flow bypassを併用したクモ膜下出血急性期破裂脳動脈瘤治療例の検討

  Kimura Hidehito, Okamura Yusuke, 小山 淳二, 中溝 聡, Kohmura Eiji

  The 72nd Annual Meeting of the Japan Neurosurgical Society, Oct. 2013, Japanese, Annual Meeting of the Japan Neurosurgical Society, 横浜, 目的：2004年10月以降演者が経験した急性期破裂脳動脈瘤手術141例中バイパス併用手術は9例、ここから主にhigh flow bypass症例を検討しbypassの適応と問題点などを検討する。症例1：50歳男性。H&K Grade II SAH。血管撮影上P com Aの直前までのRt. ICA解離。同日STA-MCA assist bypass併用下にECA-SVG-M2バイパスを行い解離部トラップ、病変摘出。術後経過良好。DSAでグラフトの開存は良好,mRS1。症例2：90歳男性、H&K Grade II SAH、Lt. IC-PC AN(3mm)、同日クリッピング術施行。Day 8に再破裂しDSAにて同部位仮性動脈瘤を認め、同日再手術。内頸動脈の温存が困難と思われ、STA-MCA bypass併用下にECA-SVG-M2バイパスを作成後病変部, Domestic conference

  Poster presentation


• 頭蓋咽頭腫に対する治療方針と治療成績

  Kimura Hidehito, Taniguchi Masaaki, Kohmura Eiji

  The 18th Annual Meeting of the Japanese Congress for Brain Tumor Surgery, Sep. 2013, Japanese, Annual Meeting of the Japanese Congress for Brain Tumor Surgery, 大津, 【目的】頭蓋咽頭腫に対する我々の治療戦略を報告、治療成績を検討する。 【方法】2002年1月以降主に神戸大学病院にて手術を行った頭蓋咽頭腫20例28手術を対象。男性12例、女性8例、平均年齢41.6歳（9歳〜75歳）、平均観察期間は64ヶ月（6ヶ月〜137ヶ月）。手術アプローチ、腫瘍摘出度、再発及び追加加療の有無、術前後の視機能、内分泌機能、術後KPS等について検討した。 【結果】20例中14例はbasal interhemispheric approach(BIA)、残り6例はそれぞれpterional ,subfrontal,FOZ approach,transsphenoidal approach施行。肉眼的全摘出は13例で達成、亜全摘出5例、部分摘出が2例。後者7例中3例は術後γナイフを照射。 F/U期間中例に7例に再発を認め内6例は亜全摘・, Domestic conference

  [Invited]

  Nominated symposium


• Cilostazole administration with combination enteral and parenteral nutrition therapy remarkably improve outcome after subarachnoid hemorrhage.

  Kimura Hidehito, Okamura Yusuke, Yosiyuki Chiba, Junji Koyama, Hosoda Kokichi, Kohmura Eiji

  Vasospasm 2013, Jul. 2013, English, Vasospasm, Lucerne, スイス, Object: Cerebral vasospasm (VS) is a main cause of morbidity and mortality following aneurysmal subarachnoid hemorrhage (SAH). Cilostazol, a selective inhibitor of phosphodiesterase 3, is recently known to attenuate cerebral vasospasm owing to its antiplatelet and vasodilatory effects. In order to prevent VS further, we hypothesize patients after SAH should be given much more n, International conference

  Oral presentation


• Surgical anatomy for endoscopic transasal skull base surgery

  Taniguchi Masaaki, Kimura Hidehito, Kota Masaaki, Kohmura Eiji

  The 25th Annual Meeting of Japanese Society for Skull Base Surgery, Jun. 2013, Japanese, Annual Meeting of Japanese Society for Skull Base Surgery, 名古屋, 経鼻的内視鏡手術は、その特殊な術野のため新たな解剖学的知識の習得を必要とする。海綿静脈洞を中心とした傍鞍部はそのフロンティア領域のひとつとも言えるが、本法の頭蓋底腫瘍への適応拡大に際しては同部位の解剖学的知識の習得がより重要と考え、屍体献体を用いた検討を行った。ホルマリン固定した18献体において実際の手術を忠実に再現するよう経鼻的内視鏡下に傍鞍部へのアプローチは内頚動脈の背側(medial)、腹側(lateral)の各corridorに分けて検討し、斜視鏡も用いた手術における実際の留意点を、特に内頚動脈および脳神経との関連において提示する。Optico-carotid recessなどの骨上の指標を対応する硬膜内解剖であるproximal/distal ringと対比させ、proximal ringの内側への延長と推測される、内頚動脈C3部から鞍隔膜, Domestic conference

  [Invited]

  Nominated symposium


• Transpetrosal approach with revascularization for the posterior circulation aneurysms in the acute stage

  Kimura Hidehito, Okamura Yusuke, 小山 淳二, 中溝 聡, 藤本 陽介, 前山 昌博, Kohmura Eiji

  The 25th Annual Meeting of Japanese Society for Skull Base Surgery, Jun. 2013, Japanese, Annual Meeting of Japanese Society for Skull Base Surgery, 名古屋, transpetrosal approachは脳深部脳幹周囲病変に極めて有効なアプローチである。脳血管外科手術では脳底動脈本幹部や後大脳動脈P2にアプローチする際に特に有効で、最近の代表例を提示して手技のコツ、工夫等併せて報告する。症例1：34歳女性、H&K Grade IV SAH、左側頭葉に大型脳出血、CTAにて左後大脳動脈P2に動脈瘤を認め同日緊急手術。側頭開頭にて側頭葉内血腫を除去後、STA-PCAバイパスのためpetrosectomyを行って手術施行(mRS4)。症例2：81歳女性。H&K Grade IV SAH,CTAにて脳底動脈本幹部前面小動脈瘤。同アプローチにて右後大脳動脈P2と脳底動脈を充分露出、大伏在静脈を用いてV3-P2バイパスを行いラッピング施行(mRS4)。考察：脳血管外科手術では時にPCAやSCAへのバイパスを必要とする, Domestic conference

  Oral presentation


• 診断に苦慮した後頭蓋窩hemangioblastomaの一例

  橋口 充, 溝脇 卓, Akutsu Nobuyuki, Tanaka Kazuhiro, Kimura Hidehito, Hosoda Kokichi, Kohmura Eiji

  第65回日本脳神経外科学会近畿支部学術集会、第67回近畿脊髄外科研究会, Apr. 2013, Japanese, 日本脳神経外科学会近畿支部、近畿脊髄外科研究会, 大阪, 【症例】35歳男性 【主訴】頭痛、嘔吐 【現病歴】数ヶ月前から頭痛および嘔吐があり、近医にて後頭蓋窩腫瘍を指摘され精査加療目的で紹介となった。 【現症】意識清明、うっ血乳頭 【神経放射線学的所見】頭部単純CTにて左小脳に長径約4cmの高吸収、低吸収の混在する腫瘍を認め、脳室拡大を認めた。MRIでは内部にflow voidを認め均一に増強される腫瘤で、周囲小脳と脳幹に著明な浮腫を伴っていた。また硬膜に付着部を有すると思われた。血管撮影では著明な腫瘍濃染像を認め、栄養血管は主に中硬膜動脈、上行咽頭動脈、後頭動脈、上小脳動脈であった。左S状静脈洞は概ね閉塞していた。術前診断としてhemangiopericytomaを考え左S状静脈洞を含めて全摘出を行うこととした。 【入院経過】外側後頭下開頭に後方経錐体到達法を併用し開頭腫瘍摘出術を行った。術中所見では腫瘍, Domestic conference

  Oral presentation


• The tips for SCA/PCA anastomosis for young neurosurgeon based on the perrsonal experiences

  Kimura Hidehito, Okamura Yusuke, 小山 淳二, Kohmura Eiji

  The 22nd Conference on Neurosurgical Techniques and Tools, Apr. 2013, Japanese, Conference on Neurosurgical Techniques and Tools, 松本, 〈目的〉脳血管障害の外科治療において、典型的STA-MCA吻合術以外のバイパス術が必要な症例は多くはないが行わねばならない機会を想定しておく必要がある。後方循環系へのバイパス術では深部での縫合となるため各種工夫が必要で、SCAあるいはPCAをレシピエントとするバイパス術を実際に術者として行って感じた具体的なポイントを報告する。〈手術の要点〉まずSCAへのバイパス術はsubtemporal approach で行うが、体位はpresigmoid approach への拡大も考えPark Benchとし頭頂側を充分下げて固定する。中頭蓋底ぎりぎりの開頭を心がけるが、ドリルを用いての骨の"庇”を除去し、中頭蓋底に沿った視軸を確保する。髄液ドレナージを有効に使うと共に、側頭葉の圧排はvein of Labbleの静脈洞流入部近くから徐々に前方に向う。側頭葉下, Domestic conference

  Oral presentation


• Our surgical experience for aneurysmal SAH by using high flow bypass in acute stages

  Kimura Hidehito, Okamura Yusuke, 小山 淳二, 中溝 聡, 藤本 陽介, 前山 昌博, Kohmura Eiji

  STROKE2013, Mar. 2013, Japanese, 日本脳卒中学会、日本脳卒中の外科学会, 東京, 【目的】演者がこれまでに施行した急性期破裂動脈瘤手術137例中バイパス併用症例は9例、ここから主にhigh flow bypass併用症例を提示し、bypassの適応と問題点などを検討する。【症例1】50歳男性。H&K Grade II SAH。血管撮影上P com Aの直前までのRt.ICA解離。同日STA-MCA assist bypass併用下にECA-SVG-M2バイパスを行い解離部トラップ、病変摘出。術後経過良好。DSAでグラフトの開存は良好、mRS1。【症例2】90歳男性、H&K Grade II SAH、Lt.IC-PC AN(3mm)、同日クリッピング術施行。Day8に再破裂しDSAにて同部位仮性動脈瘤を認め、同日再手術。内頸動脈の温存が困難と思われ、STA-MCA bypass併用下にECA-SVG-M2バイパスを作, Domestic conference

  Oral presentation


• 80歳以上高齢者くも膜下出血直達術の治療成績

  Kimura Hidehito, 三宅 茂, 小山 淳二, Kota Masaaki, Kohmura Eiji

  第26回日本老年脳神経外科学会, Mar. 2013, Japanese, 日本老年脳神経外科学会, 東京, 高齢者のくも膜下出血の予後は一般的に不良と言われ、その治療適応、手段などについて未だ議論が絶えない。我々はこれまで80歳以上の高齢者においても全身状態に問題がなければ重症度に関わらず積極的に急性期開頭クリッピング術を第一選択としてきた。その治療成績について検討する。【方法】2007年4月より2012年6月までに急性期破裂脳動脈瘤クリッピング術を施行したのは219例で、内80歳以上の37例（17％）を対象とした。原則来院24時間以内にクリッピング術を施行、術後の血圧管理はnormotensionとし積極的なtriple H療法は行わず。また2010年3月以降の18例は80歳未満の症例と異なり術後脳血管攣縮予防のための低分子デキストランの点滴は行わずに管理。また同時期からくも膜下出血術後には年齢を問わず脳血管攣縮予防の観点からシロスタゾール内服を行った。, Domestic conference

  Public symposium


• 当院におけるドクターヘリ導入後の脳出血診療へ及ぼす影響

  Okamura Yusuke, Kimura Hidehito, 中溝 聡, 藤本 陽介, 前山 昌博, 小林 誠人

  The 71st Annual Meeting of the Japan Neurosurgical Society, Oct. 2012, Japanese, Japan Neurosurgical Society, 大阪, 【はじめに】当院では平成22年4月より兵庫県/京都府/鳥取県と3県合同事業として日本海側 で初めてのドクターヘリの運行を開始しています。現在、基幹病院として事実上半径100km圏 内の患者の搬送を行っており、3次医療圏の対象人口は約70万人であります。開始当初より1年 間で1040件のドクターヘリ出動回数と日本でも有数の出動件数であったが、昨年度は1129件と さらに増加し北近畿での救急医療の中心的な役割を担っています。【方法・目的】今回、H22年4月~H23年3月まで(H22年度)の1年間およびH23年4月~H24年3月まで(H23年 度)の1年間におけるドクターヘリによる脳卒中患者の搬送割合やその内訳の変遷、さらには 脳出血患者の搬送時間・臨床経過・予後等についてドクターヘリ導入以前の症例も含め比較検 討を行った。, Domestic conference

  Poster presentation


• 当院におけるシロスタゾールを用いたくも膜下出血後脳血管攣縮予防対策-症候性脳血管攣縮ゼロを目指して-

  Kimura Hidehito, Okamura Yusuke, 中溝 聡, 藤本 陽介, 前山 昌博

  The 71st Annual Meeting of the Japan Neurosurgical Society, Oct. 2012, Japanese, Japan Neurosurgical Society, 大阪, 【目的】くも膜下出血後の脳血管攣縮(VS)は予後悪化の重要な因子であるが、いまだ特効薬は ない。近年シロスタゾール(CSZ)の予防効果が示唆されている。我々はVSの予防に栄養状態の 維持・改善が重要との見地から、術後早期より高カロリー輸液に経口摂取あるいは経管栄養を 併用して行うHybrid療法を提唱し併用して行っている。VSに対するCSZとHybrid療法併用の有 効性について検討した。【対象と方法】2008年4月から2011年12月までに当院に搬送されたく も膜下出血全175例の内、急性期開頭クリッピング術を行ったのは137例、内画像評価ができた 126例を対象。2010年4月よりHybrid療法を導入。Hybrid療法導入後のA群58例、Hybrid療法導 入前B群68例。導入前のB群には術翌日から塩酸ファスジル投与、ハ, Domestic conference

  Poster presentation


• 頭蓋咽頭腫に対する治療方針の治療成績

  Kimura Hidehito, 三宅 茂, Kohmura Eiji

  第17回日本脳腫瘍の外科学会, Sep. 2012, Japanese, 日本脳腫瘍の外科学会, 横浜, 【目的】頭蓋咽頭腫に対する我々の治療戦略を報告、治療成績を検討する。【方法】2002年1月以降神戸大学病院及び当院にて手術を行った頭蓋咽頭腫18例25手術を対象。男性10例、女性8例、平均年齢41.1歳（9歳〜74歳）、平均観察期間は57ヶ月（5ヶ月〜125ヶ月）。手術アプローチ、腫瘍摘出度、再発及び追加治療の有無、術前後の視機能、内分泌機能、術後KPS等について検討した。【結果】18例中14例はbasal interhemispheric approach(BIA)、残り4例はそれぞれpterional,subfrontal,FOZ approach ,transsphenoidal approach施行。肉眼的全摘出は13例で達成され、亜全摘例4例、部分摘出が1例。術後5例中3例は術後γナイフを照射。F/U期間中6例に再発を認め内5例は亜全摘・部, Domestic conference

  Public symposium


• 静脈洞血栓症に合併した小児くも膜下出血の1例

  藤本 陽介, Okamura Yusuke, 中溝 聡, 前山 昌博, Kimura Hidehito

  第64回日本脳神経外科学会近畿支部学術集会, Sep. 2012, Japanese, 日本脳神経外科学会近畿支部, 大阪, 小児くも膜下出血は稀であるが、今回我々は副鼻腔炎の頭蓋内波及から静脈洞血栓症を来たし、静脈性のうっ血によるくも膜下出血を発症した小児の一例を経験したので報告する。症例：9歳女児副鼻腔炎の診断で小児科加療中、発熱、頭痛、嘔吐にて発症、2日後に左外転神経麻痺が出現し救急外来受診した。頭部CTにて橋前面に首座をもつくも膜下出血を認めた。CTAでは明らかな動脈瘤、AVM等の出血源を認めなかったが、椎骨脳底動脈に血管攣縮を疑う高度狭窄を認めた。MRI所見ではBPASにて椎骨脳底動脈の解離は否定的、DWIにて血管攣縮の影響を疑う脳梗塞を認め、造影では錐体周囲の頭蓋底硬膜の左優位の造影肥厚像を認めた。血管撮影にて錐体静脈に血流停滞を認め、静脈洞血栓症と診断した。シロスタゾール、塩酸ファスジル、バランス管理による血管攣縮治療と副鼻腔炎に対する抗生剤治療を実施し病状の, Domestic conference

  Oral presentation


• 安全な基本的頭蓋底手術手技の継承について-受ける立場から-

  Kimura Hidehito, 千葉 義幸, Okamura Yusuke, 中溝 聡, 藤本 陽介, 前山 昌博, Kohmura Eiji

  第24回日本頭蓋底外科学会, Jul. 2012, Japanese, 日本頭蓋底外科学会, 東京, 頭蓋底外科手術の手技そのものは概ね確立していると思われるが、やはり重要な事はいかにそれを継承していくかであると思われる。受け継ぐ立場である演者であるが、前床突起削除、錐体骨削除など基本的頭蓋底手術手技を安全に行うコツについて最近の代表例を提示して報告する。症例1：52歳女性、視野障害にてはっしょうした右内頸動脈眼動脈分岐部動脈瘤。前床突起を硬膜外にドリルにて削除し硬膜輪を開放、動脈瘤はやや大型の動脈瘤でsuction decompressin下にクリッピングを行った。術後視野悪化なく経過良好、症例2：59歳女性、右目視野障害にて発症した前床突起部髄膜腫。硬膜下にアプローチして腫瘍を概ね摘出後超音波骨メスを用いて前床突起を一部削除、視神経管内腫瘍を摘出した。術後視野改善傾向。症例3：69歳女性。再発頭蓋底髄膜腫。腫瘍は海綿静脈洞からメッケル腔を経て後頭, Domestic conference

  Oral presentation


• バイパスを併用した脳動脈瘤の治療経験—High Flow Bypass症例を中心に−

  Kimura Hidehito, Okamura Yusuke, 中溝 聡, 藤本陽介, 前山昌博

  The 12th FEN Video Conference, Jul. 2012, Japanese, FEN, 札幌, バイパスを併用した脳動脈瘤手術の内、最近当院にて経験したHigh Flow Bypass症例を中心に報告する。症例1：50歳男性。頭痛にて近医受診MRI施行、Rt. ICA (C2 portion) の解離を認め当院搬送。搬送中に破裂、H&K Grade II SAH。血管撮影上Rt. ICA(C2)の解離、遠位部はP com Aの直前まで。同日STA-MCA assist bypass併用下にECA-SVG-M2バイパスを行い解離部トラップ、病変摘出。術後スパズムの徴候なく経過良好。術後DSAでグラフトの猫出良好。症例2：90歳男性、SAH (H&K Grade II)、CTAにてLt. IC-PC AN(3mm)、同日クリッピング術施行。Day 8に再破裂、DSAにて同部位仮性動脈瘤を認め、同日緊急で再手術。内頸動脈の温存が困難と, Domestic conference

  Oral presentation


• 当院におけるHybrid療法のくも膜下出血後脳血管攣縮予防効果

  Kimura Hidehito, 千葉 義幸, Okamura Yusuke, 山本 祐輔, 藤本 陽介

  STROKE2012, Apr. 2012, Japanese, 日本脳卒中学会、日本脳卒中の外科学会, 福岡, 【目的】くも膜下出血後の脳血管攣縮(VS)は予後悪化の重要な因子であるが、いまだ特効薬はない。抗血小板薬であるシロスタゾール(CSZ)は血管内皮保護作用、血管拡張作用など多数の薬理作用を有しており近年VSの予防効果が示唆されている。また当院ではVSの予防として、術後の栄養状態の維持・改善が有効との見地から術後早期より中心静脈カテーテルによる高カロリー輸液に経口摂取あるいは経管栄養を併用して行うHybrid療法を行っている。VSに対するシロスタゾールとHybrid療法の有効性について検討した。【対象と方法】2010年4月よりHybrid療法を導入。2009年4月から2011年3月までに当院に搬送されたくも膜下出血全94例の内、急性期開頭クリッピング術を行ったのは82例、うち画像評価ができた76例を対象とした。Hybrid療法 導入後のA群(38例)とH, Domestic conference

  Oral presentation


• Surgical techniques for non-experts to keep safety and reliability in carotid endarterectomy

  Kimura Hidehito, 千葉 義幸, Okamura Yusuke, 山本 祐輔, 藤本 陽介, Hosoda Kokichi, Kohmura Eiji

  第21回脳神経外科手術と機器学会, Mar. 2012, Japanese, 脳神経外科手術と機器学会, 大阪, Domestic conference

  Oral presentation


• 80歳以上の高齢者のくも膜下出血ー破裂脳動脈瘤クリッピング術の治療成績ー

  三宅 茂, Kimura Hidehito, 小山 淳二, Kota Masaaki, Kohmura Eiji

  第25回日本老年脳神経外科学会, Mar. 2012, Japanese, 日本老年脳神経外科学会, 東京, Domestic conference

  Oral presentation


• 高齢者（80歳以上）の破裂脳動脈瘤クリッピング術の治療成績

  三宅 茂, Kimura Hidehito, 小山 淳二, Kota Masaaki, Kohmura Eiji

  社団法人日本脳神経外科学会第70回学術総会, Oct. 2011, Japanese, 日本脳神経外科学会, 横浜, Domestic conference

  Poster presentation


• Acute stroke cases in remote areas after introduction air ambulance

  千葉 義幸, Kimura Hidehito, 石井 大嗣, 塩見 亮司, 堀 達雄, 小林 誠人

  STROKE2011（第36回日本脳卒中学会総会、第40回日本脳卒中の外科学会、第27回スパズム・シンポジウム）, Aug. 2011, Japanese, 日本脳卒中学会、日本脳卒中の外科学会、スパズム・シンポジウム, 東京, Domestic conference

  Poster presentation


• Indication and limitation of direct surgery for posterior circulation aneurysms

  Kimura Hidehito, 千葉 義幸, 石井 大嗣, 塩見 亮司, 堀 達雄, Kohmura Eiji

  STROKE2011（第36回日本脳卒中学会総会、第40回日本脳卒中の外科学会、第27回スパズム・シンポジウム）, Aug. 2011, Japanese, 日本脳卒中学会、日本脳卒中の外科学会、スパズム・シンポジウム, 東京, Domestic conference

  Oral presentation


• Nuclear choline acetyltransferase activates transcription of a high-affinity choline transporter.

  Matsuo A, JPBellier, Nishimura Mitsushige, Yasuhara O, Saito Naoaki, Kimura Hidehito

  8th IBRO world congress of Neuroscience, Jul. 2011, English, IBRO, フィレンツエ, イタリア, International conference

  Poster presentation


• 高齢者の軽症くも膜下出血における予後悪化因子の検討

  三宅 茂, Kimura Hidehito, 太田 耕平, 小山 淳二, 千葉 義幸, 石井 大嗣, Kohmura Eiji

  日本脳神経外科学会第69回学術集会, Oct. 2010, Japanese, 日本脳神経外科学会, 福岡, Domestic conference

  Oral presentation


• 安全・確実なCEAの継承 - シャント使用の重要性-

  Kimura Hidehito, 千葉 義幸, 石井 大嗣, 塩見 亮司, 堀 達雄, Hosoda Kokichi, Kohmura Eiji

  日本脳神経外科学会第69回学術集会, Oct. 2010, Japanese, 日本脳神経外科学会, 福岡, Domestic conference

  Poster presentation


• 脊髄動静脈瘻におけるmultidetector row CT angiography(MDCTA)の有用性

  Fujita Atsushi, Kimura Hidehito, 井上 悟志, Hosoda Kokichi, Kohmura Eiji

  STROKE2010（第35回日本脳卒中学会総会、第39回日本脳卒中の外科学会、第26回スパズム・シンポジウム）, Apr. 2010, Japanese, 日本脳卒中学会、日本脳卒中の外科学会, 岩手, Domestic conference

  Oral presentation


• 顕微鏡的多発血管炎に合併した破裂動脈瘤の一例

  Kimura Hidehito, Akutsu Nobuyuki, 塩見 亮司, Nakai Kentaro, Kanazawa Kenji, Kohmura Eiji

  STROKE2010（第35回日本脳卒中学会総会、第39回日本脳卒中の外科学会、第26回スパズム・シンポジウム）, Apr. 2010, Japanese, 日本脳卒中学会、日本脳卒中の外科学会, 岩手, Domestic conference

  Oral presentation


• 頚動脈狭窄症の治療におけるMRI plaque imagineの臨床意義について

  Akutsu Nobuyuki, Hosoda Kokichi, Fujita Atsushi, Kimura Hidehito, 青山 信和, Kohmura Eiji

  STROKE2010（第35回日本脳卒中学会総会、第39回日本脳卒中の外科学会、第26回スパズム・シンポジウム）, Apr. 2010, Japanese, 日本脳卒中学会、日本脳卒中の外科学会, 岩手, Domestic conference

  Oral presentation


• MRI plaque imagingに基づく頚動脈狭窄症に対するCEAとカSの選択ーhigh risk CEAの成績検討を踏まえてー

  Hosoda Kokichi, Fujita Atsushi, Akutsu Nobuyuki, Kimura Hidehito, Kohmura Eiji

  第9回日本頸部脳血管治療学会, Apr. 2010, Japanese, 日本頸部血管治療学会, 横浜, Domestic conference

  Oral presentation


• CEAの真のハイリスクファクターとMRI plaque imagingに基づいた頚動脈狭窄症に対するCEAとCASの選択

  Hosoda Kokichi, Fujita Atsushi, Akutsu Nobuyuki, Kimura Hidehito, Kohmura Eiji

  STROKE2010（第35回日本脳卒中学会総会、第39回日本脳卒中の外科学会、第26回スパズム・シンポジウム）, Apr. 2010, Japanese, 日本脳卒中学会、日本脳卒中の外科学会, 岩手, Domestic conference

  Oral presentation


• 対側後頭動脈後下小脳動脈吻合術を用いて治療しえた破裂後下小脳動脈遠位部

  Kimura Hidehito, Taniguchi Masaaki, 阿久津 宣之, 塩見 亮司, Kohmura Eiji

  第19回脳神経外科手術と機器学会, Mar. 2010, Japanese, 脳神経外科手術と機器学会, 東京, Domestic conference

  Oral presentation


• 広範囲頭蓋形成術後に皮膚欠損をきたし形成外科的に筋皮弁移植術を行った5例

  近藤 威, Kimura Hidehito, Kohmura Eiji, Hashikawa Kazunobu, 田原 真也

  第19回脳神経外科手術と機器学会, Mar. 2010, Japanese, 脳神経外科手術と機器学会, 東京, Domestic conference

  Oral presentation


• STA-MCA吻合術後過灌流症候群の検討

  Kimura Hidehito, Kohmura Eiji

  第14回関西脳神経外科手術研究会, Dec. 2009, Japanese, 関西脳神経外科手術研究会, 大阪, Domestic conference

  Oral presentation


• 悪性神経膠腫におけるpseudo-progressionの臨床的検討

  田中 宏知, 西原 賢在, Sasayama Takashi, Kimura Hidehito, 近藤 威, 荒井 篤, Kohmura Eiji

  第68回日本脳神経外科学会 学術総会, Oct. 2009, Japanese, 日本脳神経外科学会, 東京, Domestic conference

  Oral presentation


• STA-MCA吻合術術後過灌流症候群の検討

  Kimura Hidehito, 山本 大輔, Kohmura Eiji

  第68回日本脳神経外科学会 学術総会, Oct. 2009, Japanese, 日本脳神経外科学会, 東京, Domestic conference

  Oral presentation


• 腎癌脳転移に対するsunitinibによる分子標的治療の経験

  山本 大輔, 西原 賢在, Sasayama Takashi, 近藤 威, Kimura Hidehito, Kohmura Eiji, 倉橋 俊史, 安尾 健作, Kawakami Fumi, Itoh Tomoo

  第58回日本脳神経外科学会 近畿支部学術集会, Sep. 2009, Japanese, 日本脳神経外科学会 近畿支部, 大阪, Domestic conference

  Oral presentation


• 斜台部脊索腫に対する斜視鏡を併用した内視鏡下経蝶形骨洞手術

  堀 達雄, Taniguchi Masaaki, Akutsu Nobuyuki, Kimura Hidehito, Kohmura Eiji

  第58回日本脳神経外科学会 近畿支部学術集会, Sep. 2009, Japanese, 日本脳神経外科学会 近畿支部, 大阪, Domestic conference

  Oral presentation


• Cavernous malformations with and without venous malformatios:Pitfalls of MR images.

  近藤 威, 内橋 義人, Tanaka Kazuhiro, Kimura Hidehito, Hosoda Kokichi, Kohmura Eiji

  第24回日本脳神経外科国際フォーラム(JNEF), Sep. 2009, English, 岐阜, International conference

  Oral presentation


• 膠芽腫におけるMGMTのプロモーターメチレーションと予後

  田中 宏知, Sasayama Takashi, 西原 賢在, Kimura Hidehito, 近藤 威, Kohmura Eiji

  第39回兵庫県脳神経外科医懇話会, Jul. 2009, Japanese, 兵庫県脳神経外科医懇話会, 神戸, Domestic conference

  Oral presentation


• 再発頭蓋底脊索腫および髄膜腫に対する治療戦略

  Taniguchi Masaaki, Kimura Hidehito, 近藤 威, Kohmura Eiji

  第21回日本頭蓋底外科学会, Jul. 2009, Japanese, 日本頭蓋底外科学会, 福岡, Domestic conference

  Oral presentation


• 外側後頭下開頭時の髄液漏予防のための工夫

  Kimura Hidehito, Kohmura Eiji

  第21回日本頭蓋底外科学会, Jul. 2009, Japanese, 日本頭蓋底外科学会, 福岡, Domestic conference

  Oral presentation


• 外側後頭下開頭時の髄液漏予防のための工夫

  Kimura Hidehito, Kohmura Eiji

  第18回脳神経外科手術と機器学会CTNN, Apr. 2009, Japanese, 日本神経外傷学会, 秋田, Domestic conference

  Oral presentation


• 我々のバイパス練習法〜手頃でなじみある有効な方法を目指して〜

  Kimura Hidehito, Kohmura Eiji

  第18回脳神経外科手術と機器学会CTNN, Apr. 2009, Japanese, 日本神経外傷学会, 秋田, Domestic conference

  Oral presentation


• Anterior temporal approachを用いたBA-SCA分岐部脳動脈瘤の治療経験

  Kimura Hidehito, Kohmura Eiji

  第34回日本脳卒中会総会・第38回日本脳卒中の外科学会・第25回スパジム・シンポジウム, Mar. 2009, Japanese, 日本脳卒中会総会・日本脳卒中の外科学会・スパジム・シンポジウム, 島根, Domestic conference

  Oral presentation


• Analysis of Complications in Radical Surgery for Malignant Skull Base Tumors

  Kohmura Eiji, Kimura Hidehito, Nibu Ken-ichi, Tahara Shinya

  The 9th Asian-Oceanian International Congress on Skull Base Surgery, Nov. 2008, English, Asian-Oceanian International Congress on Skull Base Surgery, 大阪, 韓国, International conference

  Oral presentation


• 頭蓋底悪性腫瘍手術における合併症と対策

  Kimura Hidehito, Kohmura Eiji, Sakagami Yoshio, Nibu Ken-ichi, Tahara Shinya

  第67回社団法人日本脳神経外科学会総会, Oct. 2008, Japanese, 社団法人日本脳神経外科学会総会, 岩手, Domestic conference

  Oral presentation


• 視神経・視床下部germinomaの1例

  Nishihara Masamitsu, Aihara Hideo, Uchihashi Yoshito, Sasayama Takashi, Kondo Takeshi, Kimura Hidehito, Kohmura Eiji, Itoh Tomoo

  第56回日本脳神経外科会近畿支部学術集会・第68回近畿脳腫瘍研究会, Sep. 2008, Japanese, 日本脳神経外科会近畿支部・近畿脳腫瘍研究会, 大阪, Domestic conference

  Oral presentation


• QOLを考慮した錐体部ないし斜台錐体部髄膜炎の治療戦略

  Kohmura Eiji, Aihara Hideo, Kimura Hidehito

  第２０回記念日本頭蓋底外科学会, Jun. 2008, Japanese, 日本頭蓋底外科学会, 東京, Domestic conference

  Oral presentation


• STA - MCA吻合術後過灌流症候群を来たした２例

  Kimura Hidehito, Nakamura Mitsugu, Kohmura Eiji

  第37回日本脳卒中の外科学会, Mar. 2008, Japanese, 日本脳卒中の外科学会, 京都, Domestic conference

  Oral presentation


• 脳梗塞急性期にCASを施行した４症例

  Nakamura Mitsugu, Kimura Hidehito, Kohmura Eiji

  第23回日本脳神経血管内治療学会総会, Nov. 2007, Japanese, 日本脳神経血管内治療学会, 神戸, Domestic conference

  Oral presentation


• 錐体骨先端部病変に対するLateral Supracerebellar Transtentortiral Approchの使用経験

  Kimura Hidehito, Nakamura Mitsugu, Kohmura Eiji

  第11回日本脳腫瘍の外科学会, Nov. 2007, Japanese, 日本脳腫瘍の外科学会, 神戸, Domestic conference

  Oral presentation


• 内頚動脈内膜剥離術の術中脳波変化とその予測因子

  Kimura Hidehito, Nakamura Mitsugu, Kohmura Eiji

  第66回社団法人日本脳神経外科学会総会, Oct. 2007, Japanese, 社団法人日本脳神経外科学会, 東京, Domestic conference

  Poster presentation


• 小脳出血に対する仰臥位での開頭手術

  Kimura Hidehito, Nakamura Mitsugu, Kohmura Eiji

  第66回社団法人日本脳神経外科学会総会, Oct. 2007, Japanese, 社団法人日本脳神経外科学会, 東京, Domestic conference

  Poster presentation


• 頚部内頸動脈偽閉塞病変（pseudo-occlusion)に対する頸動脈内膜剥離術－術前検査と周術期管理の注意点－

  Nakamura Mitsugu, Kimura Hidehito

  第66回社団法人日本脳神経外科学会総会, Oct. 2007, Japanese, 社団法人日本脳神経外科学会, 東京, Domestic conference

  Oral presentation


• 頭蓋底手術後数年を経過して発症した遅発性髄液鼻漏の３例

  Kimura Hidehito, Saito Minoru, Kohmura Eiji

  第19回日本頭蓋底外科学会, Jul. 2007, Japanese, 日本頭蓋底外科学会, 東京, Domestic conference

  Oral presentation


• 小脳出血に対する仰臥位での開頭手術

  Kimura Hidehito, Saito Minoru, Kohmura Eiji

  第16回脳神経外科手術と機器学会, Apr. 2007, Japanese, 脳神経外科手術と機器学会, 東京, Domestic conference

  Oral presentation

• Developments of surgical systems for skull base surgery and surgical education

  魚住 洋一, 篠山 隆司, 藤田 祐一, 中井 友昭, 木村 英仁

  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Kobe University, 01 Apr. 2022 - 31 Mar. 2025


• Investigation for the molecular biological role of myoglobin in the cerebral aneurysm walls

  木村 英仁, 篠山 隆司

  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Kobe University, 01 Apr. 2022 - 31 Mar. 2025


• Comprehensive analysis of cerebral metabolism and cerebrospinal fluid changes in subarachnoid hemorrhage patients

  Uozumi Yoichi

  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Kobe University, 01 Apr. 2019 - 31 Mar. 2022

  In patients with subarachnoid hemorrhage, about 20% develop a phenomenon called symptomatic vasospasm, which causes sequelae such as paralysis, impaired consciousness, aphasia and so on. Its onset is unpredictable. The purpose of this study is to predict this symptomatic vasospasm. We investigated accumulated patients' blood sampling data, and newly showed that arginine vasopressin (AVP), adrenocorticotropic hormone (ACTH), and serum cortisol on the onset of subarachnoid hemorrhage are significantly higher in patients with symptomatic vasospasm than in patients without symptomatic vasospasm. It was suggested that these data could be used to predict cerebral vasospasm and be helpful for future patients with subarachnoid hemorrhage to get better outcome.


• 格子ボルツマン法を用いたMRI単独CFD解析法による脳動脈瘤増大因子の同定

  木村 英仁

  学術研究助成基金助成金／基盤研究(C), Apr. 2017 - Mar. 2020, Principal investigator

  Competitive research funding


• MRI単独CFD解析法を用いた脳動脈瘤ブレブ形成における壁面せん断応力の役割に関する研究

  木村英仁

  タケダリサーチサポート, 2016, Principal investigator


• 骨髄細胞移植によるmicrogliaをターゲットとした虚血損傷脳に対する治療法確立の可能性

  木村英仁、相原英夫、甲村英二

  第３４回日本心臓財団研究奨励金, 2008 - 2009