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KATSURADA NaokoGraduate School of Medicine / Faculty of Medical SciencesAssistant Professor
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■ Paper- The respiratory rate is an important factor for assessing patient status and detecting changes in the severity of illness. Real-time determination of the respiratory rate will enable early responses to changes in the patient condition. Several methods of wearable devices have enabled remote respiratory rate monitoring. However, gaps persist in large-scale validation, patient-specific calibration, standardization and their usefulness in clinical practice has not been fully elucidated. The aim of this study was to evaluate the accuracy of 2 wearable stretch sensors, C-STRECH® which is used in clinical practice and a novel stretchable capacitor in measuring the respiratory rate. The respiratory rate of 20 healthy subjects was measured by a spirometer with the stretch sensor applied to 1 of 5 locations (umbilicus, lateral abdomen, epigastrium, lateral chest, or chest) of their body at rest while they were in a sitting or supine position before or after exercise. The sensors detected the largest amplitudes at the epigastrium and umbilicus compared to other sites of measurement for the sitting and supine positions, respectively. At rest, the respiratory rate of the sensors had an error of 0.06 to 2.39 breaths/minute, whereas after exercise, an error of 1.57 to 3.72 breaths/minute was observed compared to the spirometer. The sensors were able to detect the respiratory rate of healthy volunteers in the sitting and supine positions, but there was a need for improvement in detection after exercise.Jul. 2024, Medicine, 103(29) (29), e38818, English, International magazineScientific journal
- (有)科学評論社, Apr. 2024, 呼吸器内科, 45(4) (4), 373 - 376, Japanese【希少肺疾患はどこまで解明されたか】肺胞微石症
- BACKGROUND/AIM: Immune checkpoint inhibitors (ICI) are a novel medication for non-small cell lung cancer (NSCLC). Recent reports indicated that baseline tumor size (BTS) relates to the efficacy of ICI therapy for melanoma, but no study exists for NSCLC. This study aimed to evaluate the utility of BTS for ICI therapy. PATIENTS AND METHODS: Data from 58 patients diagnosed with NSCLC who underwent ICI monotherapy, were retrospectively analyzed. Patients were divided into two groups according to BTS (below 101 mm, above 101 mm). The primary endpoint was progression-free survival (PFS) and the secondary endpoint was overall survival (OS). RESULTS: PFS of patients with a large BTS was significantly shorter than that of those with a small BTS (median; 2.07 [95% confidence interval [CI]=0.99-6.77] months versus 6.39 [95%CI=4.17-11.50] months) (p=0.044). OS of patients with large BTS was also significantly shorter (p<0.01). CONCLUSION: BTS is a predictive and prognostic negative factor of ICI therapy for NSCLC.Feb. 2019, Anticancer Res, 39(2) (2), 815 - 825, English, International magazine[Refereed]Scientific journal
- Jan. 2019, Intern Med, EnglishSuccessful Treatment of ROS1-rearranged Lung Cancer Complicated by Hypertrophic Pulmonary Osteoarthropathy with Crizotinib Therapy: A Case Report[Refereed]Scientific journal
- BACKGROUND: The effectiveness of inactivated influenza vaccine (IIV) against laboratory-confirmed influenza pneumonia in older adults remains to be established. METHODS: Pneumonia patients aged ≥65 years who visited a study hospital in Chiba, Japan, were prospectively enrolled from February 2012 to January 2014. Sputum samples were collected from participants and tested for influenza virus by polymerase chain reaction assays. Influenza vaccine effectiveness (IVE) against laboratory-confirmed influenza pneumonia was estimated by a test-negative design. RESULTS: Among a total of 814 pneumonia patients, 42 (5.2%) tested positive for influenza: 40 were positive for influenza A virus, and two were positive for influenza B virus. The IVE against laboratory-confirmed influenza pneumonia was 58.3% (95% confidence interval, 28.8-75.6%). The IVE against influenza pneumonia hospital admission, severe pneumonia, and death was 60.2% (95% CI, 22.8-79.4%), 65.5% (95% CI, 44.3-78.7%), and 71% (95% CI, -62.9% to 94.8%), respectively. In the subgroup analyses, the IVE against influenza pneumonia was higher for patients with immunosuppressive conditions (85.9%; 95% CI, 67.4-93.9%) than for those without (48.7%; 95% CI, 2.7-73%) but did not differ by patients' statin use status. CONCLUSION: IIV effectively reduces the risk of laboratory-confirmed influenza pneumonia in older adults.May 2018, Vaccine, 36(21) (21), 2960 - 2967, English, International magazine[Refereed]Scientific journal
- Dec. 2017, BMC Infect Dis, 17(1) (1), 755, EnglishThe impact of virus infections on pneumonia mortality is complex in adults: a prospective multicentre observational study[Refereed]Scientific journal
- 2017, HUMAN VACCINES & IMMUNOTHERAPEUTICS, 13(3) (3), 543 - 550, English[Refereed]Scientific journal
- (一社)日本呼吸器内視鏡学会, Mar. 2023, 気管支学, 45(2) (2), 164 - 164, Japanese
- Jan. 2018, Medicina, 55(1) (1), 106 - 109, Japanese【気管支喘息・COPD診療に強くなる】気管支喘息・COPDの慢性期コントロール COPD慢性期治療[Invited]Introduction commerce magazine
- 第58回 日本肺癌学会学術集会, Nov. 2018, Japanese, 横浜, Domestic conference免疫チェックポイント阻害薬で治療したPD-L1陽性肺癌に対する好中球リンパ球比の検討Oral presentation
- 第59回 日本肺癌学会学術集会, Nov. 2018, Japanese, 横浜, Domestic conference免疫チェックポイント阻害剤投与例における赤血球容積粒度分布幅の有用性Oral presentation
- 第61回 日本肺癌学会学術集会, Nov. 2018, Japanese, 横浜, Domestic conference間質性陰影合併肺癌における抗PD-1抗体による間質性陰影増悪のリスク因子の検討Oral presentation
- 24th World Asthma Congress 2018, Oct. 2018, English, INTERASTHMA Globa Asthma Association, Tokyo, International conferenceXenon Ventilation Computed Tomography and Bronchial Thermoplasty for AsthmaOral presentation
- 第221回 日本内科学会 近畿地方会, Sep. 2018, Japanese, 大阪, Domestic conference多発神経炎の発症に,腫瘍由来の自己抗体の関与が疑われた肺小細胞肺癌の1例Oral presentation
- 第221回 日本内科学会 近畿地方会, Sep. 2018, Japanese, 大阪, Domestic conferenceペムブロリズマブ投与後に免疫関連胆管炎を発症した肺腺癌の1例Oral presentation
- 第16回 日本臨床腫瘍学会学術集会, Jul. 2018, Japanese, 神戸, Domestic conference非小細胞肺癌(非扁平上皮癌)完全切除症例に対するCDDP+PEMショートハイドレーション療法による術後補助化学療法の認容性試験Oral presentation
- 第49回職業・環境アレルギー学会, Jul. 2018, Japanese, 横浜, Domestic conference香川県中讃地区における農作業関連喘息に関しての検討Oral presentation
- 第91回 日本呼吸器学会, Jul. 2018, Japanese, 神戸, Domestic conferenceアレクチニブによる治療中に神経内分泌癌へ形質転換したと考えられたALK融合遺伝子陽性肺腺癌の一例Oral presentation
- 第108回肺癌学会関西支部会, Jun. 2018, Japanese, 大阪, Domestic conference肺性肥大性骨関節症を合併したROS1融合遺伝子陽性肺癌の一例Oral presentation
- 第41回日本呼吸器内視鏡学会学術集会, May 2018, Japanese, 東京, Domestic conference当科における気管支鏡検査後に発症した呼吸器感染症の検討Oral presentation
- 第41回日本呼吸器内視鏡学会学術集会, May 2018, Japanese, 東京, Domestic conference当科におけるEBUS-TBNA検査の実態に関する検討Oral presentation
- 第58回日本呼吸器学会学術講演会, Apr. 2018, Japanese, 大阪, Domestic conference連続パルスオキシメトリーによる在宅酸素療法患者の夜間低酸素血症の調査Poster presentation
- 第218回内科学会近畿地方会, Dec. 2017, Japanese, 日本内科学会, 神戸, Domestic conference辺縁系脳炎に対するステロイド治療中に播種性Mycobacterium abscessus感染症を発症した1例Oral presentation
- 第90回日本呼吸器学会近畿地方会, Dec. 2017, Japanese, 日本呼吸器学会, 大阪, Domestic conference化学療法により症状の改善を認めたLambert-Eaton症候群合併肺小細胞癌の1例Poster presentation
- 第89回日本呼吸器学会近畿地方会, Jul. 2017, Japanese, 日本呼吸器学会, 大阪, Domestic conferenceNivolumab 投与後に腱鞘炎,多発関節炎を発症した肺腺癌の1例Oral presentation
- 第216回日本内科学会近畿地方会, Jul. 2017, Japanese, 日本内科学会, 大阪, Domestic conferenceHDR症候群に肺扁平上皮癌を発症した1例Oral presentation
- 第40回日本呼吸器内視鏡学会学術集会, Jun. 2017, Japanese, 日本呼吸器内視鏡学会, 長崎, Domestic conferenceEGFR遺伝子変異陽性肺癌における気管支鏡での再生検についての検討Oral presentation
- 第40回日本呼吸器内視鏡学会学術集会, Jun. 2017, Japanese, 日本呼吸器内視鏡学会, 長崎, Domestic conferenceEBUS-GS後のTBAC追加による末梢肺病変診断への有用性に関する検討Oral presentation
- 第66回日本アレルギー学会学術大会, Jun. 2017, Japanese, 日本アレルギー学会, 東京, Domestic conference2016年度喘息吸入薬の吸入指導に関するアンケートOral presentation
- 第91回日本感染症学会学術講演会, Apr. 2017, Japanese, 日本感染症学会, 東京, Domestic conference成人市中発症肺炎における呼吸器ウイルスの臨床的役割Oral presentation