Research activity information

• Role of CXCR4/SDF1 signaling in the initial migration of cardiac neural crest cells

  Saori Tani-Matsuhana, Yumi Unozu, Kunio Inoue

  Last, Elsevier BV, Jun. 2025, Biochemical and Biophysical Research Communications, 767, 151914 - 151914, English, International magazine

  [Refereed]

  Scientific journal


• The cardiac neural crest gene MafB ectopically directs CXCR4 expression in the trunk neural crest

  Saori Tani-Matsuhana, Yuga Kawata, Kunio Inoue

  Last, Elsevier BV, Mar. 2023, Developmental Biology, 495, 1 - 7, English, International magazine

  [Refereed]

  Scientific journal


• The germ cell‐specific TAP‐like protein NXF‐2 forms a novel granular structure and is required for tra‐2 3′UTR‐dependent mRNA export in Caenorhabditis elegans

  Takashi Miwa, Keigo Ohtani, Kunio Inoue, Hiroshi Sakamoto

  Wiley, Oct. 2022, Genes to Cells, 27(10) (10), 621 - 628, English, International magazine

  [Refereed]

  Scientific journal


• SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns

  Kazuhiro Fukumura, Rei Yoshimoto, Luca Sperotto, Hyun-Seo Kang, Tetsuro Hirose, Kunio Inoue, Michael Sattler, Akila Mayeda

  Human pre-mRNA introns vary in size from under fifty to over a million nucleotides. We searched for essential factors involved in the splicing of human short introns by screening siRNAs against 154 human nuclear proteins. The splicing activity was assayed with a model HNRNPH1 pre-mRNA containing short 56-nucleotide intron. We identify a known alternative splicing regulator SPF45 (RBM17) as a constitutive splicing factor that is required to splice out this 56-nt intron. Whole-transcriptome sequencing of SPF45-deficient cells reveals that SPF45 is essential in the efficient splicing of many short introns. To initiate the spliceosome assembly on a short intron with the truncated poly-pyrimidine tract, the U2AF-homology motif (UHM) of SPF45 competes out that of U2AF⁶⁵ (U2AF2) for binding to the UHM-ligand motif (ULM) of the U2 snRNP protein SF3b155 (SF3B1). We propose that splicing in a distinct subset of human short introns depends on SPF45 but not U2AF heterodimer.

  Springer Science and Business Media LLC, Dec. 2021, Nature Communications, 12(1) (1), 4910 - 4910, English, International magazine, Co-authored internationally

  [Refereed]

  Scientific journal


• Identification of regulatory elements for MafB expression in the cardiac neural crest

  Saori Tani-Matsuhana, Kunio Inoue

  Last, Elsevier BV, Sep. 2021, Cells & Development, 167, 203725, English

  [Refereed]

  Scientific journal


• Tethered Function Assay to Study RNA-Regulatory Proteins in Zebrafish

  Yuichiro Mishima, Kunio Inoue

  Springer US, Feb. 2021, Methods in Molecular Biology, 347 - 354

  [Invited]

  In book


• Forkhead box B2 inhibits the malignant characteristics of the pancreatic cancer cell line Panc-1 in vitro.

  Hiroki Fukuchi, Yukinobu Hayashida, Kunio Inoue, Yoshifusa Sadamura

  Forkhead box (FOX) proteins constitute a family of transcription factors that are evolutionarily conserved in various species ranging from yeast to humans. These proteins have functions during development as well as in adulthood. To date, many reports have described the functions of FOX family genes in cancer cells, but the role of FOXB2 is not well understood. In one of the pancreas ductal adenocarcinoma cell lines, Panc-1 cells, we showed here that FOXB2 expression is barely detectable and that CpG islands in the 5' regions of the FOXB2 are highly methylated. These findings led us to hypothesize that FOXB2 acts as a tumor suppressor. To clarify our hypotheses, we investigated the effects of FOXB2 over-expression in Panc-1 cells. We obtained FOXB2 stable transfectants, and these clones exhibited reduced spheroid formation ability. Expression of β-catenin, which is reported to be over-expressed in various cancer cells, was highly suppressed in FOXB2 stable transfectants. Moreover, side population (SP) cell fractions, which have a high tumorigenesis and metastatic potential, as well as anchorage-independent growth ability, were reduced. These results suggest that FOXB2 has the ability to inhibit the malignant characteristics of Panc-1 in vitro.

  Oct. 2019, Genes to Cells, 24(10) (10), 674 - 681, English, International magazine

  [Refereed]

  Scientific journal


• MRG-1 is required for both chromatin-based transcriptional silencing and genomic integrity of primordial germ cells in Caenorhabditis elegans.

  Takashi Miwa, Kunio Inoue, Hiroshi Sakamoto

  In Caenorhabditis elegans, germline cells remain transcriptionally silenced during embryogenesis. The transcriptional silencing is achieved by two different mechanisms: One is the inhibition of RNA polymerase II in P2-P4 cells at the establishment stage, and another is chromatin-based silencing in two primordial germ cells (PGCs) at the maintenance stage; however, the molecular mechanism underlying chromatin-based silencing is less understood. We investigated the role of the chromodomain protein MRG-1, which is an essential maternal factor for germline development, in transcriptional silencing in PGCs. PGCs lacking maternal MRG-1 showed increased levels of two histone modifications (H3K4me2 and H4K16ac), which are epigenetic markers for active transcription, and precocious activation of germline promoters. Loss of MES-4, a H3K36 methyltransferase, also caused similar derepression of the germline genes in PGCs, suggesting that both MRG-1 and MES-4 function in chromatin-based silencing in PGCs. In addition, the mrg-1 null mutant showed abnormal chromosome structures and a decrease in homologous recombinase RAD-51 foci in PGCs, but the mes-4 null mutant did not show such phenotypes. Taken together, we propose that MRG-1 has two distinct functions: chromatin-based transcriptional silencing and preserving genomic integrity at the maintenance stage of PGCs.

  May 2019, Genes to Cells, 24(5) (5), 377 - 389, English, International magazine

  [Refereed]

  Scientific journal


• Transcriptome profiling of the cardiac neural crest reveals a critical role for MafB.

  Tani-Matsuhana, S, Vieceli, F. M, Gandhi, S, Inoue, K, Bronner, M. E

  Dec. 2018, Developmental Biology, 444(1) (1), S209 - S218, English

  [Refereed]

  Scientific journal


• Developmental mechanisms of migratory muscle precursors in medaka pectoral fin formation

  Saori Tani-Matsuhana, Rie Kusakabe, Kunio Inoue

  Last, Sep. 2018, Development Genes and Evolution, 228(5) (5), 189 - 196, English

  [Refereed]

  Scientific journal


• Splicing activator RNPS1 suppresses errors in pre-mRNA splicing: A key factor for mRNA quality control.

  Fukumura, A, Inoue, K, Mayeda, A

  Feb. 2018, Biochem. Biophys. Res. Commun., 496, 921 - 926, English

  [Refereed]

  Scientific journal


• DND protein functions as a translation repressor during zebrafish embryogenesis

  Manami Kobayashi, Saori Tani-Matsuhana, Yasuka Ohkawa, Hiroshi Sakamoto, Kunio Inoue

  Mar. 2017, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 484(2) (2), 235 - 240, English

  [Refereed]

  Scientific journal


• The Exon Junction Complex controls the efficient and faithful splicing of a subset of transcripts involved in mitotic cell-cycle progression.

  Fukumura, K, Wakabayashi, S, Kataoka, N, Sakamoto, H, Suzuki, Y, Nakai, K, Mayeda, A, Inoue, K

  Last, Dec. 2016, International Journal of Molecular Sciences, 17(8) (8), 1153, English

  [Refereed]

  Scientific journal


• Control of the heat stress-induced alternative splicing of a subset of genes by hnRNP K

  Koichi Yamamoto, Mari T. Furukawa, Kazuhiro Fukumura, Arisa Kawamura, Tomoko Yamada, Hitoshi Suzuki, Tetsuro Hirose, Hiroshi Sakamoto, Kunio Inoue

  Sep. 2016, GENES TO CELLS, 21(9) (9), 1006 - 1014, English

  [Refereed]

  Scientific journal


• Restricted distribution of mrg-1 mRNA in C.elegans primordial germ cells through germ granule-independent regulation

  Takashi Miwa, Teruaki Takasaki, Kunio Inoue, Hiroshi Sakamoto

  Nov. 2015, GENES TO CELLS, 20(11) (11), 932 - 942, English

  [Refereed]

  Scientific journal


• Interaction and colocalization of HERMES/RBPMS with NonO, PSF, and G3BP1 in neuronal cytoplasmic RNP granules in mouse retinal line cells

  Mari T. Furukawa, Hiroshi Sakamoto, Kunio Inoue

  Apr. 2015, GENES TO CELLS, 20(4) (4), 257 - 266, English

  [Refereed]

  Scientific journal


• Roles of mRNA Fate Modulators Dhh1 and Pat1 in TNRC6-dependent Gene Silencing Recapitulated in Yeast

  Shiho Makino, Yuichiro Mishima, Kunio Inoue, Toshifumi Inada

  Mar. 2015, JOURNAL OF BIOLOGICAL CHEMISTRY, 290(13) (13), 8331 - 8347, English

  [Refereed]

  Scientific journal


• The Origin and Migration of Primordial Germ Cells in Sturgeons

  Taiju Saito, Martin Psenicka, Rie Goto, Shinji Adachi, Kunio Inoue, Katsutoshi Arai, Etsuro Yamaha

  Feb. 2014, PLOS ONE, 9(2) (2), English

  [Refereed]

  Scientific journal


• MiR-124 is Involved in Post-transcriptional Regulation of Polypyrimidine Tract Binding Protein 1 (PTBP1) During Neural Development in the Medaka, Oryzias latipes

  Yumiko Kato, Rie Kusakabe, Kunio Inoue, Shin Tochinai

  Nov. 2013, ZOOLOGICAL SCIENCE, 30(11) (11), 891 - 900, English

  [Refereed]

  Scientific journal


• Characterization of the compact bicistronic microRNA precursor, miR-1/miR-133, expressed specifically in Ciona muscle tissues

  Rie Kusakabe, Saori Tani, Koki Nishitsuji, Miyuki Shindo, Kohji Okamura, Yuki Miyamoto, Kenta Nakai, Yutaka Suzuki, Takehiro G. Kusakabe, Kunio Inoue

  Last, Jan. 2013, GENE EXPRESSION PATTERNS, 13(1-2) (1-2), 43 - 50, English

  [Refereed]

  Scientific journal


• A Specific Set of Exon Junction Complex Subunits Is Required for the Nuclear Retention of Unspliced RNAs in Caenorhabditis elegans

  Masami Shiimori, Kunio Inoue, Hiroshi Sakamoto

  Jan. 2013, MOLECULAR AND CELLULAR BIOLOGY, 33(2) (2), 444 - 456, English

  [Refereed]

  Scientific journal


• Developmental expression and evolution of muscle-specific microRNAs conserved in vertebrates

  Tani, Saori, Kuraku, Shigehiro, Sakamoto, Hiroshi, Inoue, Kunio, Kusakabe, Rie

  2013, Evolution & Development, 15(4) (4), 293 - 304, English

  [Refereed]

  Scientific journal


• Functional and direct interaction between the RNA binding protein HuD and active Akt1

  Toshinobu Fujiwara, Akira Fukao, Yumi Sasano, Hidenori Matsuzaki, Ushio Kikkawa, Hiroaki Imataka, Kunio Inoue, Shogo Endo, Nahum Sonenberg, Christian Thoma, Hiroshi Sakamoto

  Mar. 2012, NUCLEIC ACIDS RESEARCH, 40(5) (5), 1944 - 1953, English

  [Refereed]

  Scientific journal


• Translational inhibition by deadenylation-independent mechanisms is central to microRNA-mediated silencing in zebrafish

  Yuichiro Mishima, Akira Fukao, Tomoyoshi Kishimoto, Hiroshi Sakamoto, Toshinobu Fujiwara, Kunio Inoue

  Jan. 2012, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(4) (4), 1104 - 1109, English

  [Refereed]

  Scientific journal


• Identification of MIWI-associated Poly(A) RNAs by immunoprecipitation with an anti-MIWI monoclonal antibody

  Takahiro Nishibu, Yukinobu Hayashida, Saori Tani, Sadamu Kurono, Kanako Kojima-Kita, Ryo Ukekawa, Tsutomu Kurokawa, Satomi Kuramochi-Miyagawa, Toru Nakano, Kunio Inoue, Susumu Honda

  2012, BIOSCIENCE TRENDS, 6(5) (5), 248 - 261, English

  [Refereed]

  Scientific journal


• Microtubule association of a neuronal RNA-binding protein HuD through its binding to the light chain of MAP1B

  Yuki Fujiwara, Katsumi Kasashima, Kuniaki Saito, Miho Fukuda, Akira Fukao, Yumi Sasano, Kunio Inoue, Toshinobu Fujiwara, Hiroshi Sakamoto

  May 2011, BIOCHIMIE, 93(5) (5), 817 - 822, English

  [Refereed]

  Scientific journal


• Genomic organization and embryonic expression of miR-430 in medaka (Oryzias latipes): Insights into the post-transcriptional gene regulation in early development

  Saori Tani, Rie Kusakabe, Kiyoshi Naruse, Hiroshi Sakamoto, Kunio Inoue

  Jan. 2010, GENE, 449(1-2) (1-2), 41 - 49, English

  [Refereed]

  Scientific journal


• [Molecular mechanism of exon definition and alternative splicing].

  Fukumura K, Inoue K

  Dec. 2009, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 54(16 Suppl) (16 Suppl), 2032 - 2037, Japanese, Domestic magazine

  [Refereed]

  Scientific journal


• The ELAV Protein HuD Stimulates Cap-Dependent Translation in a Poly(A)- and eIF4A-Dependent Manner

  Akira Fukao, Yumi Sasano, Hiroaki Imataka, Kunio Inoue, Hiroshi Sakamoto, Nahum Sonenberg, Christian Thoma, Toshinobu Fujiwara

  Dec. 2009, MOLECULAR CELL, 36(6) (6), 1007 - 1017, English

  [Refereed]

  Scientific journal


• DAZL Relieves miRNA-Mediated Repression of Germline mRNAs by Controlling Poly(A) Tail Length in Zebrafish

  Yasuaki Takeda, Yuichiro Mishima, Toshinobu Fujiwara, Hiroshi Sakamoto, Kunio Inoue

  Oct. 2009, PLOS ONE, 4(10) (10), English

  [Refereed]

  Scientific journal


• A novel application of metabolomics in vertebrate development

  Shunsuke Hayashi, Shinichi Akiyama, Yutaka Tamaru, Yasuaki Takeda, Toshinobu Fujiwara, Kunio Inoue, Akio Kobayashi, Shingo Maegawa, Eiichiro Fukusaki

  Aug. 2009, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 386(1) (1), 268 - 272, English

  [Refereed]

  Scientific journal


• U1-independent pre-mRNA splicing contributes to the regulation of alternative splicing

  Kazuhiro Fukumura, Ichiro Taniguchi, Hiroshi Sakamoto, Mutsuhito Ohno, Kunio Inoue

  Apr. 2009, NUCLEIC ACIDS RESEARCH, 37(6) (6), 1907 - 1914, English

  [Refereed]

  Scientific journal


• Evolution of vertebrate myogenesis, with special reference to the morphological variety of skeletal muscles

  Kusakabe, Rie, Kuraku, Shigehiro, Kuratani, Shigeru, Inoue, Kunio

  2009, Mechanisms of Development, 126

  [Refereed]

  Scientific journal


• Localization of c- mos mRNA around the animal pole in the zebrafish oocyte with Zor-1/Zorba

  Hitoshi Suzuki, Toshifumi Tsukahara, Kunio Inoue

  2009, BIOSCIENCE TRENDS, 3(3) (3), 96 - 104, English

  [Refereed]

  Scientific journal


• A useful approach to total analysis of RISC-associated RNA

  Yukinobu Hayashida, Takahiro Nishibu, Kunio Inoue, Tsutomu Kurokawa

  2009, BMC Research Notes, 2, English

  [Refereed]

  Scientific journal


• Distribution of U3 small nucleolar RNA and fibrillarin during early embryogenesis in Caenorhabditis elegans

  Yumi Sasano, Yusuke Hokii, Kunio Inoue, Hiroshi Sakamoto, Chisato Ushida, Toshinobu Fujiwara

  Jun. 2008, BIOCHIMIE, 90(6) (6), 898 - 907, English

  [Refereed]

  Scientific journal


• Tissue-specific splicing regulator Fox-1 induces exon skipping by interfering E complex formation on the downstream intron of human F1 gamma gene

  Kazuhiro Fukumura, Ayako Kato, Yui Jin, Takashi Ideue, Tetsuro Hirose, Naoyuki Kataoka, Toshinobu Fujiwara, Hiroshi Sakamoto, Kunio Inoue

  Aug. 2007, NUCLEIC ACIDS RESEARCH, 35(16) (16), 5303 - 5311, English

  [Refereed]

  Scientific journal


• Spatiotemporal localization of germ plasm RNAs during zebrafish oogenesis

  Kyoko Kosaka, Koichi Kawakami, Hiroshi Sakamoto, Kunio Inoue

  Apr. 2007, MECHANISMS OF DEVELOPMENT, 124(4) (4), 279 - 289, English

  [Refereed]

  Scientific journal


• MRG-1, an autosome-associated protein, silences X-linked genes and protects germline immortality in Caenorhabditis elegans

  Teruaki Takasaki, Zheng Liu, Yasuaki Habara, Kiyoji Nishiwaki, Jun-ichi Nakayama, Kunio Inoue, Hiroshi Sakamoto, Susan Strome

  Feb. 2007, DEVELOPMENT, 134(4) (4), 757 - 767, English

  [Refereed]

  Scientific journal


• Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430

  Yuichlro Mishima, Antonio J. Giraldez, Yasuaki Takeda, Toshinobu Fujiwara, Hiroshi Sakamoto, Alexander F. Schier, Kunio Inoue

  Nov. 2006, CURRENT BIOLOGY, 16(21) (21), 2135 - 2142, English

  [Refereed]

  Scientific journal


• Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs

  AJ Giraldez, Y Mishima, J Rihel, RJ Grocock, S Van Dongen, K Inoue, AJ Enright, AF Schier

  Apr. 2006, SCIENCE, 312(5770) (5770), 75 - 79, English

  [Refereed]

  Scientific journal


• Visualization of primordial germ cells in vivo using GFP-nos1 3 ' UTR mRNA

  Taiju Saito, Takafumi Fujimoto, Shingo Maegawa, Kunio Inoue, Minoru Tanaka, Katsutoshi Arai, Etsuro Yamaha

  2006, INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY, 50(8) (8), 691 - 700, English

  [Refereed]

  Scientific journal


• Bruno-like protein is localized to zebrafish germ plasm during the early cleavage stages

  Y Hashimoto, H Suzuki, Y Kageyama, K Yasuda, K Inoue

  Jan. 2006, GENE EXPRESSION PATTERNS, 6(2) (2), 201 - 205, English

  Scientific journal


• Splicing potentiation by growth factor signals via estrogen receptor phosphorylation

  Y Masuhiro, Y Mezaki, M Sakari, KI Takeyama, T Yoshida, K Inoue, J Yanagisawa, S Hanazawa, BW O'Malley, S Kato

  Jun. 2005, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(23) (23), 8126 - 8131, English

  [Refereed]

  Scientific journal


• Germ-line chimera produced by blastoderm transplantation in zebrafish

  NAGAI TERUMI, OTANI SATOSHI, SAITO TAIJU, MAEGAWA SHINGO, INOUE KUNIO, ARAI KATSUTOSHI, YAMAHA ETSURO, TERUMI NAGAKI, SATOSHI OTANI, TAIJU SAITO, SHINGO MAEGAWA, KUNIO INOUE, KATSUTOSHI ARAI, ETSURO YAMAHA, Laboratory of Breeding Science Graduate School of Fisheries Science Hokkaido University:(Present address)Laboratory of Regulatory Biology Department of Biology Faculty of Science Toyama University, Laboratory of Breeding Science Graduate School of Fisheries Science Hokkaido University, Laboratory of Breeding Science Graduate School of Fisheries Science Hokkaido University, Laboratory of Breeding Science Graduate School of Fisheries Science Hokkaido University:(Present address)Department of Biology University of Pennsylvania, Laboratory of Molecular and Developmental Biology Graduate School of Biological Sciences Nara Institute of Science and Technology:(Present address)Graduate School of Science and Technology Kobe University, Laboratory of Breeding Science Graduate School of Fisheries Science Hokkaido University, Nanae Fresh Water Laboratory Field Science Center for Northern Biosphere Hokkaido University

    To elucidate the effects of blastoderm graft for chimeric-fish production on further development, transplantations of upper, lower or entire part of blastoderm were performed onto the animal part of host embryos during the blastula stage in zebrafish. In the case of upper, all resultant chimeric embryos developed normally, while in the lower part, many acephalic embryos appeared. When the entire blastoderm was transplanted, many resultant embryos showed normal phenotype with extra cell-mass, while a few had double axis. vas mRNA, one of the markers of PGCs, also kept the expressions in both donor and recipient blastomeres in transplantation of the entire blastoderm. Donor PGCs were frequently detected at germinal anlagen in histological sections of 6-day larvae developed from transplantations of lower and entire blastoderm, but seldom in those of the upper part. These results might suggest that graft transplantation was effective for production of germ-line chimera, but sometimes caused un-regulaory differentiation of graft cells under the community effect.
  

  The Japanese Society of Fisheries Science, Jan. 2005, NIPPON SUISAN GAKKAISHI, 71(1) (1), 1 - 9, Japanese

  Scientific journal


• Germ-line chimera produced by blastoderm transplantation in zebrafish

  T Nagai, S Otani, T Saito, S Maegawa, K Inoue, K Arai, E Yamaha

  Jan. 2005, NIPPON SUISAN GAKKAISHI, 71(1) (1), 1 - 9, Japanese

  [Refereed]

  Scientific journal


• The formation of primordial germ cells from germline cells in spherical embryos derived from the blastodisc of 2-cell embryos in goldfish, Carassius auratus

  S Otani, T Kitauchi, T Saito, S Sakao, S Maegawa, K Inoue, K Arai, E Yamaha

  2005, INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY, 49(7) (7), 843 - 850, English

  Scientific journal


• TAP/NXF1, the primary mRNA export receptor, specifically interacts with a neuronal RNA-binding protein HuD

  K Saito, T Fujiwara, J Katahira, K Inoue, H Sakamoto

  Aug. 2004, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 321(2) (2), 291 - 297, English

  [Refereed]

  Scientific journal


• Localized maternal factors are required for zebrafish germ cell formation

  Y Hashimoto, S Maegawa, T Nagai, E Yamaha, H Suzuki, K Yasuda, K Inoue

  Last, Apr. 2004, DEVELOPMENTAL BIOLOGY, 268(1) (1), 152 - 161, English

  [Refereed]

  Scientific journal


• RBD-1, a nucleolar RNA-binding protein, is essential for Caenorhabditis elegans early development through 18S ribosomal RNA processing

  E Saijou, T Fujiwara, T Suzaki, K Inoue, H Sakamoto

  Feb. 2004, NUCLEIC ACIDS RESEARCH, 32(3) (3), 1028 - 1036, English

  [Refereed]

  Scientific journal


• A vertebrate RNA-binding protein Fox-1 regulates tissue-specific splicing via the pentanucleotide GCAUG

  Y Jin, H Suzuki, S Maegawa, H Endo, S Sugano, K Hashimoto, K Yasuda, K Inoue

  Feb. 2003, EMBO JOURNAL, 22(4) (4), 905 - 912, English

  [Refereed]

  Scientific journal


• Zebrafish DAZ-like protein controls translation via the sequence 'GUUC'

  S Maegawa, M Yamashita, K Yasuda, K Inoue

  Sep. 2002, GENES TO CELLS, 7(9) (9), 971 - 984, English

  [Refereed]

  Scientific journal


• The germ cell lineage identified by vas-mRNA during the embryogenesis in goldfish

  S Otani, S Maegawa, K Inoue, K Arai, E Yamaha

  May 2002, ZOOLOGICAL SCIENCE, 19(5) (5), 519 - 526, English

  [Refereed]

  Scientific journal


• Regulation of alternative splicing of alpha-actinin transcript by Bruno-like proteins

  H Suzuki, Y Jin, H Otani, K Yasuda, K Inoue

  Feb. 2002, GENES TO CELLS, 7(2) (2), 133 - 141, English

  [Refereed]

  Scientific journal


• Biochemical identification of Xenopus pumilio as a sequence-specific cyclin B1 mRNA-binding protein that physically interacts with a nanos homolog, Xcat-2, and a cytoplasmic polyadenylation element-binding protein

  S Nakahata, Y Katsu, K Mita, K Inoue, Y Nagahama, M Yamashita

  Jun. 2001, JOURNAL OF BIOLOGICAL CHEMISTRY, 276(24) (24), 20945 - 20953, English

  [Refereed]

  Scientific journal


• Vegetal localization of the maternal mRNA encoding an EDEN-BP/Bruno-like protein in zebrafish

  Hitoshi Suzuki, Shingo Maegawa, Takahiro Nishibu, Tomoyasu Sugiyama, Kunio Yasuda, Kunio Inoue

  May 2000, Mechanisms of Development, 93(1-2) (1-2), 205 - 209, English

  [Refereed]

  Scientific journal


• Maternal mRNA localization of zebrafish DAZ-like gene

  S Maegawa, K Yasuda, K Inoue

  Mar. 1999, MECHANISMS OF DEVELOPMENT, 81(1-2) (1-2), 223 - 226, English

  [Refereed]

  Scientific journal


• Disruption of the splicing enhancer sequence within exon 27 of the dystrophin gene by a nonsense mutation induces partial skipping of the exon and is responsible for Becker muscular dystrophy

  N Shiga, Y Takeshima, H Sakamoto, K Inoue, Y Yokota, M Yokoyama, M Matsuo

  Nov. 1997, JOURNAL OF CLINICAL INVESTIGATION, 100(9) (9), 2204 - 2210, English

  [Refereed]

  Scientific journal


• Interaction of goosecoid and brachyury in Xenopus mesoderm patterning

  M Artinger, Blitz, I, K Inoue, U Tran, KWY Cho

  Jul. 1997, MECHANISMS OF DEVELOPMENT, 65(1-2) (1-2), 187 - 196, English

  [Refereed]

  Scientific journal


• Activation of two Cynops genes, fork head and sonic hedgehog, in animal cap expiants

  Takashi Takabatake, Tadashi C. Takahashi, Kunio Inoue, Masanori Ogawa, Kazuhito Takeshima

  Academic Press Inc., Jan. 1996, Biochemical and Biophysical Research Communications, 218(1) (1), 395 - 401, English

  [Refereed]

  Scientific journal


• Molecular mechanisms of Spemann's organizer formation: Conserved growth factor synergy between Xenopus and mouse

  T Watabe, S Kim, A Candia, U Rothbacher, C Hashimoto, K Inoue, KWY Cho

  Dec. 1995, GENES & DEVELOPMENT, 9(24) (24), 3038 - 3050, English

  [Refereed]

  Scientific journal


• TRANSCRIPTIONAL REGULATION OF THE SEX-LETHAL GENE BY HELIX-LOOP-HELIX PROTEINS

  K HOSHIJIMA, A KOHYAMA, WATAKABE, I, K INOUE, H SAKAMOTO, Y SHIMURA

  Sep. 1995, NUCLEIC ACIDS RESEARCH, 23(17) (17), 3441 - 3448, English

  [Refereed]

  Scientific journal


• Mechanism of alternative RNA splicing

  K Inoue, Y Shimura

  1995, TRACING BIOLOGICAL EVOLUTION IN PROTEIN AND GENE STRUCTURES, 87 - 95, English

  [Refereed]

  International conference proceedings


• Aspects of splice site selection in constitutive and alternative pre-mRNA splicing.

  Inoue, K., Ohno, M., Shimura, Y.

  Lead, 1995, Gene Expr., 4(3) (3), 177 - 182

  [Refereed]


• Control of Drosophila Sex-lethal pre-mRNA splicing by its own female-specific product.

  H Sakamoto, K Inoue, I Higuchi, Y Ono, Y Shimura

  Drosophila melanogaster somatic sexual differentiation is accomplished by serial function of the products of sex-determination genes. Sex-lethal (Sxl), is one such gene. It is functionally expressed only in female flies. The sex-specific expression of this gene is regulated by alternative mRNA splicing which results in either the inclusion or exclusion of the translation stop codon containing third exon. Although previous genetic and molecular analyses suggest that functional Sxl expression is maintained by a positive feedback loop, where the female-specific Sxl product promotes the synthesis of its own female-specific mRNA, the mechanistic details of such regulation have remained unclear. We have developed a cotransfection system using Drosophila cultured (Kc) cells in which Sxl primary transcripts are expressed with or without the female specific Sxl product. Here we show that the female-specific Sxl product induces the synthesis of its own female-specific mRNA by negative control of male-specific splicing. Deletion, substitution, and binding experiments have demonstrated that multiple uridine-rich sequences in the introns around the male-specific third exon are involved in the splicing regulation of Sxl pre-mRNA.

  Nov. 1992, Nucleic acids research, 20(21) (21), 5533 - 40, English, International magazine

  [Refereed]

  Scientific journal


• Binding of the Drosophila transformer and transformer-2 proteins to the regulatory elements of doublesex primary transcript for sex-specific RNA processing.

  K Inoue, K Hoshijima, I Higuchi, H Sakamoto, Y Shimura

  Sex-specific alternative processing of double-sex (dsx) precursor messenger RNA (pre-mRNA) is one of the key steps that regulates somatic sexual differentiation in Drosophila melanogaster. By transfection analyses using dsx minigene constructs, we identified six copies of the 13-nucleotide sequences TC(T/A)(T/A)C(A/G)ATCAACA in the female-specific fourth exon that act as the cis elements for the female-specific splicing of dsx pre-mRNA. UV-crosslinking experiments revealed that both female-specific transformer (tra) and transformer-2 (tra-2) products bind to the 13-nucleotide sequences of dsx pre-mRNA. These results strongly suggest that the female-specific splicing of dsx pre-mRNA is activated by binding of these proteins to the 13-nucleotide sequences.

  Lead, Sep. 1992, Proceedings of the National Academy of Sciences of the United States of America, 89(17) (17), 8092 - 6, English, International magazine

  [Refereed]


• CONTROL OF DOUBLESEX ALTERNATIVE SPLICING BY TRANSFORMER AND TRANSFORMER-2 IN DROSOPHILA

  K HOSHIJIMA, K INOUE, HIGUCHI, I, H SAKAMOTO, Y SHIMURA

  May 1991, SCIENCE, 252(5007) (5007), 833 - 836, English

  [Refereed]

  Scientific journal


• Binding of the Drosophila sex-lethal gene product to the alternative splice site of transformer primary transcript.

  K Inoue, K Hoshijima, H Sakamoto, Y Shimura

  Somatic sexual differentiation in Drosophila melanogaster is accomplished by a hierarchy of genes of which one, Sex-lethal (Sxl), is required for the functional female-specific splicing of the transcripts of the immediately downstream regulatory gene, transformer (tra). The first exon of the tra primary transcript is spliced to one of two acceptor sites. Splicing to the upstream site yields a messenger RNA which is neither sex-specific nor functional, but that produced after splicing to the downstream acceptor site yields a functional female-specific mRNA. Here we address the question of how the Sxl gene product determines the alternative splicing of tra primary transcripts. One suggestion is that non-sex-specific splicing to the upstream acceptor is blocked in female flies by sex-specific factors, but neither the identity of the female-specific factors nor the mechanism of the blockage has been specified. We have now performed co-transfection experiments in which Sxl complementary DNA and the tra gene are expressed in Drosophila Kc cells. Moreover, we find that female Sxl-encoded protein binds specifically to the tra transcript at or near the non-sex-specific acceptor site, implying that the female Sxl gene product is the trans-acting factor that regulates the alternative splicing.

  Lead, Mar. 1990, Nature, 344(6265) (6265), 461 - 3, English, International magazine

  [Refereed]

  Scientific journal


• A SECONDARY STRUCTURE AT THE 3' SPLICE SITE AFFECTS THE INVITRO SPLICING REACTION OF MOUSE IMMUNOGLOBULIN-MU CHAIN PRE-MESSENGER RNAS

  A WATAKABE, K INOUE, H SAKAMOTO, Y SHIMURA

  Oct. 1989, NUCLEIC ACIDS RESEARCH, 17(20) (20), 8159 - 8169, English

  [Refereed]

  Scientific journal


• Effect of the cap structure on pre-mRNA splicing in Xenopus oocyte nuclei.

  K Inoue, M Ohno, H Sakamoto, Y Shimura

  The effect of the 5' cap structure on the splicing of precursor mRNAs was investigated after the RNAs were injected into Xenopus oocyte nuclei. The precursor mRNAs synthesized in vitro in a prokaryotic transcription system with a dinucleotide, ApppG, as a primer, were extremely stable when injected into the nuclei yet behaved like uncapped pre-mRNAs in the in vitro splicing reaction. The ApppG-primed precursor mRNAs served as a control (uncapped) in the injection experiments, and their splicing reactions were compared with those of their capped (m7GpppG-primed) counterparts. The capped precursors were spliced more efficiently than the uncapped precursors. Examination of splicing of the precursor mRNA that contained three exons and two introns with a single molecule has revealed that the cap structure exerts its effect primarily on the 5'-proximal intron. Thus, the cap structure not only stabilizes precursor mRNAs but also plays a positive role in the splicing of precursor mRNAs in cells.

  Lead, Sep. 1989, Genes & development, 3(9) (9), 1472 - 9, English, International magazine

  [Refereed]

  Scientific journal

• A Distinct Subset of Human Short Introns: U2AF Heterodimer Is Replaced by SPF45 (RBM17) as General Splicing Factor

  Fukumura K, Yoshimoto R, Hirose T, Inoue K, Mayeda A

  cold spring harbor laboratory, Sep. 2019, bioRxiv, 784868, English, International magazine

  Report scientific journal


• Developmental regulation and evolution of muscle-specific microRNAs

  Rie Kusakabe, Kunio Inoue

  Dec. 2015, SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 47-48, 9 - 16, English

  [Refereed][Invited]

  Introduction scientific journal


• microRNA経路の中核因子TNRC6Aは複数のメカニズムを介して標的mRNAを抑制する

  三嶋雄一郎, 岸本友良, 深尾亜喜良, 武田耕哲, 坂本博, 藤原俊伸, 井上邦夫

  2010, 生化学


• Role and mechanism of U1-independent pre-mRNA splicing in the regulation of alternative splicing

  Kazuhiro Fukumura, Kunio Inoue

  Last, Sep. 2009, RNA Biology, 6(4) (4), 395 - 398

  [Invited]

  Introduction scientific journal


• GFP‐nos1‐3′ UTR mRNAによる始原生殖細胞(PGCs)の顕在化とそれを利用した魚類の異種間生殖系列キメラ作出の試み

  斎藤大樹, 吉川智仁, 長井輝美, 大谷哲, 藤本貴史, 相田貴紀, 井上邦夫, 前川真吾, 山羽悦郎

  01 Apr. 2003, 日本水産学会大会講演要旨集, 2003, 130, Japanese


• mRNA局在化と発生分化制御 (RNAの細胞生物学) -- (高次複合形質とRNA)

  井上 邦夫

  共立出版, Mar. 2003, 蛋白質核酸酵素, 48(4) (4), 451 - 458, Japanese


• The maintenance of vasa expression has no relevance to the mesoderm induction and axis structure in goldfish(Developmental Biology)Proceedings of the Seventy-First Annual Meeting of the Zoological Society of Japan :

  Otani S., Maegawa S., Inoue K., Arai K., Yamaha E.

  Zoological Society of Japan, 2000, Zoological science, 17, 68 - 68, English


• スプライシング促進配列を制御することによるエクソンスキッピングの誘導を用いたDuchenne型筋ジストロフィーの治療戦略

  竹島泰弘, 伊東利幸, ZAD P, 坂本博, 井上邦夫, 中村肇, 松尾雅文

  03 Aug. 1999, RNAミーティング, 1st, 33, Japanese


• PRIMORDIAL GERM CELLS LOCATE IN THE LOWER PART OF BLASTODERM AT THE MID-BLASTULA STAGE IN ZEBRAFISH(Developmental Biology)(Proceedings of the Seventieth Annual Meeting of the Zoological Society of Japan) :

  Nagai T., Otani S., Maegawa S., Inoue K., Arai K., Yamaha E.

  Zoological Society of Japan, 1999, Zoological science, 16, 60 - 60, English


• Molecular mechanism of germ cell formation in zebrafish

  MAEGAWA S, YASUDA K, INOUE K

  01 Dec. 1998, 日本分子生物学会年会プログラム・講演要旨集, 21(0) (0), Japanese


• Functional analysis of maternal RNA-binding protein in zebrafish

  SUZUKI H, MAEGAWA S, YASUDA K, INOUE K

  01 Dec. 1998, 日本分子生物学会年会プログラム・講演要旨集, 21(0) (0), Japanese


• Identification and functional analysis of zebrafish etr gene encoding Elav type RNA connectivity protein.

  NISHIBE TAKAHIRO, SUGIYAMA TOMOYASU, SUZUKI HITOSHI, MAEKAWA SHINGO, TERASHIMA KAZUHIRO, SAKASHITA EIJI, SAKAMOTO HIROSHI, YASUDA KUNIO, INOUE KUNIO

  1998, 日本発生生物学会大会発表要旨集, 31st, 93, Japanese


• In vitro Analysis of Exon Skipping Induced by Point Mutation in Splicing Enhancer Sequence in Becker Muscular Dystrophy.

  志賀宣之, 竹島泰弘, 坂本博, 井上邦夫, 横田慶之, 横山光宏, 松尾雅文

  Dec. 1997, 日本分子生物学会年会プログラム・講演要旨集, 20th, 685, Japanese

• 熱ストレス応答性のスプライシング制御機構 実験医学 Vol.34-No.19 「coding RNAルネッサンス」 p.3122-p.3126

  INOUE KUNIO

  Joint work, 羊土社, Dec. 2016, Japanese

  Scholarly book


• microRNAによる初期発生調節機構

  井上 邦夫

  Single work, 蛋白質核酸酵素, Mar. 2007, Japanese

  Others


• microRNAによるゼブラフィッシュ初期発生制御機構（実験医学）

  三嶋 雄一郎, 井上 邦夫

  Joint work, 羊土社, Mar. 2007, Japanese

  Scholarly book


• 発生分化過程におけるポリ(A)動態制御（蛋白質核酸酵素・増刊号『RNAと生命』）

  井上 邦夫

  Single work, 共立出版, 2006, Japanese

  Others


• mRNA局在化の分子機構 （実験医学増刊 Vol.22-No.17、「躍進するRNA研究」p.2545-p.2460

  三嶋 雄一郎, 坂本 博, 井上 邦夫

  Joint work, 羊土社, Nov. 2004, Japanese

  Others


• RNAスプライシングとゲノム（ゲノム医学）

  井上 邦夫

  Single work, メディカル・レビュー社, 2004, Japanese

  Others

• MafBが制御する心臓神経堤細胞の形成メカニズム

  松花沙織, 卯図優実, 川田結雅, 井上邦夫

  第23回 日本心臓血管発生研究会, Dec. 2024, Japanese, 淡路夢舞台国際会議場, Domestic conference

  Oral presentation


• Role of CXCR4/SDF1 signaling in the initial migration of cardiac neural crest cells.

  卯図優実, 井上邦夫, 松花沙織

  第47回 日本分子生物学会, Nov. 2024, Japanese, 福岡, Japan, Domestic conference

  Poster presentation


• The cardiac neural crest gene MafB ectopically directs CXCR4 expression in the trunk neural crest

  Saori Tani-Matsuhana, Yuga Kawata, Kunio Inoue

  第57回 日本発生生物学会, Jun. 2024, English, みやこめっせ/ロームシアター京都, Domestic conference

  Poster presentation


• ゼブラフィッシュの心臓形成におけるロンボメア5および6由来の心臓神経堤細胞の解析

  阪田 悠世, 松花 沙織, 川上 浩一, 井上 邦夫

  第46回日本分子生物学会年会, Dec. 2023, Japanese, 神戸, Japan, Domestic conference

  Poster presentation


• 可視光でオン・オフできるGs共役型光遺伝学ツールの開発

  酒寄朗成, 酒井祐輔, 平尚之, 阪田悠世, 小柳光正, 寺北明久, 松花沙織, 井上邦夫, 塚本寿夫

  第61回日本生物物理学会年会, Nov. 2023, English, Domestic conference

  Poster presentation


• 線虫C. elegansにおいて生殖細胞特異的なTAP様蛋白質NXF-2は新規のRNPを形成しtra-2 3ʼUTR依存的なmRNA核外輸送に必要である

  巳波 孝至, 大谷啓吾, 井上 邦夫, 坂本 博

  関西地区線虫勉強会, Jan. 2023, Japanese, Domestic conference

  Oral presentation


• The germ cell-specific TAP-like protein NXF-2 forms a novel granular structure and is required for tra-2 3ʼUTR- dependent mRNA export in Caenorhabditis elegans.

  巳波孝至, 大谷啓吾, 井上邦夫, 坂本博

  第45回 日本分子生物学会, Dec. 2022, English, 幕張メッセ, Domestic conference

  Poster presentation


• Role of MafB gene in cardiac neural crest cell development

  Saori Tani-Matsuhana, Yuga Kawata, Yusei Sakata, Kunio Inoue

  第55回日本発生生物学会, Jun. 2022, English, 金沢市文化ホール, Domestic conference

  Oral presentation


• 新しい分子機構によってスプライシングされるヒトの短いイントロン群

  福村和宏, 芳本 玲, 廣瀬 哲郎, 井上邦夫, 前田 明

  第44回 日本分子生物学会, Dec. 2021, English, 横浜（ハイブリッド）, Domestic conference

  Poster presentation


• 線虫C. elegansにおいてクロモドメイン蛋白質MRG-1の阻害はストレス応 答系の活性化に伴う成長遅延を誘導する

  巳波 孝至, 井上 邦夫, 坂本 博

  第44回 日本分子生物学会, Dec. 2021, English, 横浜（ハイブリッド）, Domestic conference

  Poster presentation


• 遺伝子解析によるヒト体液種同定法の研究

  嵯峨 渉, 井上 邦夫

  第27回 日本法科学技術学会, Nov. 2021, Japanese, オンライン, Domestic conference

  Poster presentation


• The RNA transport-related factor NXF-2 forms a novel granular structure in C. elegans germ cells

  大谷 啓悟, ⺒波 孝至, 井上 邦夫, 坂本 博

  第22回 日本RNA学会, Jul. 2021, English, オンライン, Domestic conference

  Poster presentation


• 線虫 C. elegans におけるRNA輸送関連因子NXF-2の機能解析

  大谷 啓悟, ⺒波 孝至, 井上 邦夫, 坂本 博

  線虫勉強会, Jan. 2021, Japanese, Domestic conference

  Oral presentation


• The RNA transport-related factor NXF-2 forms a novel granular structure in C. elegans germ cells.

  大谷 啓悟, 巳波 孝至, 井上 邦夫, 坂本 博

  第43回日本分子生物学会, Dec. 2020, English, Domestic conference

  Poster presentation


• A gene regulatory mechanism of early migrating cardiac neural crest cells in chicken embryo

  川田 結雅, 井上 邦夫, 松花(谷) 沙織

  第43回日本分子生物学会, Dec. 2020, English, Domestic conference

  Poster presentation


• Possible role of RNA secondary structure as thermo sensor regulating alternative splicing

  竹部 真希, 坂本 博, 井上 邦夫

  第43回日本分子生物学会, Dec. 2020, English, Domestic conference

  Poster presentation


• Control of alternative splicing during recovery period from heat stress.

  樫本 千尋, 逵本 実希, 坂本 博, 井上 邦夫

  第43回日本分子生物学会, Dec. 2020, English, Domestic conference

  Poster presentation


• SPF45/RBM17 is a novel constitutive splicing factor for a subset of short introns

  Kazuhiro Fukumura, Rei Yoshimoto, Tetsuro Hirose, Kunio Inoue, Akila Mayeda

  第４２回日本分子生物学会, Dec. 2019, English, Domestic conference

  [Invited]

  Public symposium


• 心臓神経堤細胞の細胞運命を決定する遺伝子制御機構の解析

  村上誠、井上邦夫、松花沙織

  第10回サイエンスフロンティア研究発表会, Oct. 2019, Japanese, 神戸大学大学院理学研究科, Domestic conference

  Poster presentation


• アミロイドβ線維認識に関わるNLRP3-LRR ドメインの構造特徴と認識機構の研究

  政安 梨緒, 山本 良太, 今村 比呂志, 山本 直樹, MATSUHANA SAORI, INOUE KUNIO, TSUBAKI MOTONARI, CHATANI ERI

  第19回日本蛋白質科学会年会･第71回日本細胞生物学会大会 合同年次大会, Jun. 2019, Japanese, 神戸国際会議場, Domestic conference

  Poster presentation


• A Distinct Subset of Human Short Introns with Weak Pyrimidine Tract: U2AF Heterodimer Is Replaced by SPF45/RBM17 as General Splicing Factor

  Kazuhiro Fukumura,Rei Yoshimoto,Tetsuro Hirose,Kunio Inoue,Akila Mayeda

  24th Annual Meeting of the RNA Society, Jun. 2019, English, Krakow, Poland, International conference

  [Invited]

  Oral presentation


• Transcriptome analysis of the cardiac neural crest reveals a critical role for MafB（ポスター）

  Saori Tani-Matsuhana, Kunio Inoue, Marianne Bronner

  第52回日本発生生物学会, May 2019, English, 大阪国際交流センター（大阪）, Domestic conference

  Poster presentation


• Transcriptome analysis of the cardiac neural crest reveals a critical role for MafB

  Saori Tani-Matsuhana, Kunio Inoue, Marianne Bronner

  第52回日本発生生物学会, May 2019, English, 大阪国際交流センター（大阪）, Domestic conference

  Oral presentation


• アミロイドβ線維認識に関与するNLRP3-LRRドメインの構造特徴および認識機構の解明

  政安 梨緒, 山本 良太, 今村 比呂志, 山本 直樹, MATSUHANA SAORI, INOUE KUNIO, TSUBAKI MOTONARI, CHATANI ERI

  非共有結合系の分子科学：計測技術から探る生体分子科学の新展開/研究プロジェクト「非共有結合系分子科学研究」, Jan. 2019, Japanese, 神戸大学理学研究科Z201,202, Domestic conference

  Poster presentation


• 炎症誘起タンパク質NLRP3のLRRドメインによるアミロイドβ線維の直接的認識

  政安 梨緒, 山本 良太, 今村 比呂志, 山本 直樹, MATSUHANA SAORI, INOUE KUNIO, TSUBAKI MOTONARI, CHATANI ERI

  神戸大学 研究基盤センター 若手フロンティア研究会, Dec. 2018, Japanese, 神戸大学百年記念館, Domestic conference

  Poster presentation


• 線虫C. elegansにおいてクロモドメイン蛋白質MRG-1は始原生殖細胞における転写抑制制御に必要である

  巳波 孝至, 高崎 輝恒, 井上 邦夫, 坂本 博

  第41回日本分子生物学会, Nov. 2018, Japanese, パシフィコ横浜（神奈川県）, Domestic conference

  Poster presentation


• 核局在性RNA結合タンパク質NONOの細胞内局在制御機構の解析（ポスター）

  古川 真理, 井上 邦夫

  第41回日本分子生物学会, Nov. 2018, Japanese, パシフィコ横浜（神奈川県）, Domestic conference

  Poster presentation


• 核局在性RNA結合タンパク質NONOの細胞内局在制御機構の解析

  古川 真理, 井上 邦夫

  第41回日本分子生物学会, Nov. 2018, Japanese, パシフィコ横浜（神奈川県）, Domestic conference

  Oral presentation


• トランスクリプトーム解析により明らかとなった心臓神経堤細胞におけるMafBの重要な機能（ポスター）

  松花(谷) 沙織, 井上 邦夫, Marianne Bronner

  第41回日本分子生物学会, Nov. 2018, Japanese, パシフィコ横浜（神奈川県）, Domestic conference

  Poster presentation


• トランスクリプトーム解析により明らかとなった心臓神経堤細胞におけるMafBの重要な機能

  松花(谷) 沙織, 井上 邦夫, Marianne Bronner

  第41回日本分子生物学会, Nov. 2018, English, パシフィコ横浜（神奈川県）, Domestic conference

  Oral presentation


• Identification of Tumor Suppressor RBM4a as a Repressor of Cancer-Specific Mature mRNA Re-splicing

  Toshiki Kameyama, Kazuhiro Fukumura, Masashi Nakatani, Yuta Ohtani, Kunio Inoue, Tetsuro Hirose, Akila Mayeda

  Cold Spring Harbor Asia Conference-RNA Biology, Oct. 2018, English, The Suzhou Dushu Lake Conference Center, Suzhou, China, International conference

  Oral presentation


• The chromodomain protein MRG-1 is required for global repression of Pol II-dependent transcription in the primordial germ cells in C. elegans

  巳波 孝至, 井上 邦夫, 坂本 博

  線虫研究の未来を創る会, Sep. 2018, Japanese, 国立遺伝学研究所（静岡県）, Domestic conference

  Poster presentation


• 熱ストレス応答性選択的スプライシング制御機構の解明

  川浪巧, 逵本実希, 坂本博, 井上邦夫

  第20回日本RNA学会年会, Jul. 2018, Japanese, ホテルコスモスクエア（大阪府）, Domestic conference

  Poster presentation


• Tumor Suppressor Factor RBM4a Represses Cancer-Specific mRNA Re-splicing: A Key Factor for mRNA Quality Control?

  亀山俊樹, 福村和宏, 井上邦夫, 廣瀬哲郎, 前田明

  第20回日本RNA学会年会, Jul. 2018, Japanese, ホテルコスモスクエア（大阪府）, Domestic conference

  Poster presentation


• U2AFの代わりにSPF45でスプライシングされるヒトの短いイントロン群

  福村和宏, 芳本玲, 廣瀬哲郎, 井上邦夫, 前田明

  第20回日本RNA学会年会, Jul. 2018, Japanese, ホテルコスモスクエア（大阪府）, Domestic conference

  Oral presentation


• Transcriptome analysis of the cardiac neural crest reveals a critical role for MafB

  Saori Tani-Matsuhana, Felipe Monteleone Vieceli, Shashank Gandhi, Kunio Inoue, Marianne E. Bronner

  Society for Developmental Biology 77th Annual Meeting, Jul. 2018, English, Portland, Oregon, USA, International conference

  Poster presentation


• Transcriptome analysis of the cardiac neural crest reveals a MAFB gene regulatory subcircuit

  Saori Tani-Matsuhana, Kunio Inoue, Marianne E. Bronner

  第70回日本細胞生物学会、第51回日本発生生物学会合同大会, Jun. 2018, Japanese, タワーホール船堀（東京都）, Domestic conference

  Poster presentation


• The chromodomain protein MRG-1 is required for global repression of Pol II-dependent transcription in the primordial germ cells in C. elegans

  巳波 孝至, 高崎 輝恒, 井上 邦夫, 坂本 博

  第70回日本細胞生物学会、第51回日本発生生物学会合同大会, Jun. 2018, Japanese, タワーホール船堀（東京都）, Domestic conference

  Poster presentation


• U2AF is replaced by SPF45 as general splicing factor to recognize weak pyrimidine tract and promotes splicing of human short introns

  Kazuhiro Fukumura, Rei Yoshimoto, Tetsuro Hirose, Kunio Inoue, Akila Mayeda

  The 23th Annual Meeting of the RNA Society, May 2018, English, Berkeley, California, International conference

  Oral presentation


• 熱ストレス応答性の選択的スプライシング制御機構

  井上 邦夫

  第40回日本分子生物学会年会, Dec. 2017, Japanese, 神戸ポートピアホテル（兵庫県）, Domestic conference

  [Invited]

  Invited oral presentation


• 線虫クロモドメイン蛋白質MRG-1が始原生殖細胞における転写抑制制御に必要である

  巳波 孝至, 高崎 輝恒, 井上 邦夫, 坂本 博

  第40回日本分子生物学会年会, Dec. 2017, Japanese, 神戸国際展示場2号館（兵庫県）, Domestic conference

  Poster presentation


• 核局在性RNA結合タンパク質NONOの細胞内局在制御機構と細胞質性顆粒形成機構の解析

  古川 真理, 井上 邦夫

  第40回日本分子生物学会年会, Dec. 2017, Japanese, 神戸国際展示場2号館（兵庫県）, Domestic conference

  Poster presentation


• メダカにおける胸鰭筋細胞の発生機構

  松花(谷) 沙織, 井上 邦夫

  第40回日本分子生物学会年会, Dec. 2017, Japanese, 神戸国際展示場2号館（兵庫県）, Domestic conference

  Poster presentation


• ゼブラフィッシュ網膜形成におけるRNA結合タンパク質NonOの機能解析

  宇佐美 知沙, 坂本 博, 井上 邦夫

  第40回日本分子生物学会年会, Dec. 2017, Japanese, 神戸国際展示場2号館（兵庫県）, Domestic conference

  Poster presentation


• がん抑制因子RBM4aはがん細胞特異的成熟mRNA再スプライシングを抑制する：mRNA品質保証の鍵となる因子か？

  亀山 俊樹, 福村 和宏, 井上 邦夫, 廣瀬 哲郎, 前田 明

  第40回日本分子生物学会年会, Dec. 2017, Japanese, 神戸国際展示場2号館（兵庫県）, Domestic conference

  Oral presentation


• DND protein functions as a translation repressor during zebrafish embryogenesis

  Kobayashi, M, Tani-Matsuhana, S, Ohkawa, Y, Sakamoto, H, Inoue, K

  第49回日本分子生物学会年会, Dec. 2017, Japanese, 神戸国際展示場2号館（兵庫県）, Domestic conference

  Poster presentation


• 神経文化に伴うSUMO化修飾状態の変化は、核局在性RNA結合タンパク質NONOの核外移行を誘導する

  古川 真理, 井上 邦夫

  第19回日本RNA学会年会, Jul. 2017, Japanese, 富山国際会議場（富山県）, Domestic conference

  Poster presentation


• RNPS1は細胞周期に合わせてオーロラキナーゼB遺伝子の正確なスプライシングを制御する

  福村 和宏, 井上 邦夫, 前田 明

  第19回日本RNA学会年会, Jul. 2017, Japanese, 富山国際会議場（富山県）, Domestic conference

  Oral presentation


• A Repressor Candidate of Cancer Specific mRNA Re-splicing: A Key factor for splicing fidelity or mRNA quality control?

  Toshiki Kameyama, Kazuhiro Fukumura, Kunio Inoue, Tetsuro Hirose, Akila Mayeda

  RNA2017 The 22nd Annual Meeting of the RNA Society, Jun. 2017, English, Prague, Czech Republic, International conference

  Oral presentation


• Chromodomain protein MRG-1 is required for global repression of Pol II-dependent transcription in the primordial germ cells in C. elegans

  Takashi Miwa, Teruaki Takasaki, Kunio Inoue, Hiroshi Sakamoto

  第50回日本発生生物学会, May 2017, English, タワーホール船堀（東京都）, Domestic conference

  Poster presentation


• Characterization of RNA-binding protein NonO during retinal development in zebrafish

  Chisa Usami, Hiroshi Sakamoto, Kunio Inoue

  第50回日本発生生物学会, May 2017, English, タワーホール船堀（東京都）, Domestic conference

  Poster presentation


• The developmental mechanisms of fin muscle cells in medaka, Oryzias latipes

  Saori TANI-MATSUHANA, Kunio Inoue

  第50回日本発生生物学会, May 2017, English, タワーホール船堀（東京都）, Domestic conference

  Poster presentation


• DND protein functions as a translation repressor during zebrafish embryogenesis

  Kobayashi, M, Tani-Matsuhana, S, Ohkawa, Y, Sakamoto, H, Inoue, K

  第50回日本発生生物学会, May 2017, English, タワーホール船堀（東京都）, Domestic conference

  Poster presentation


• 熱ストレス応答性の選択的スプライシング制御機構

  井上 邦夫

  第三回バイオシグナル研究会「RNAと生命情報」, Mar. 2017, Japanese, 神戸大学瀧川記念学術交流会館, Domestic conference

  [Invited]

  Invited oral presentation


• 神経分化に伴って核外移行するRNA結合タンパク質NONOは、SUMO化による細胞内局在制御を受ける

  古川 真理, INOUE KUNIO

  第39回日本分子生物学年会, Nov. 2016, Japanese, パシフィコ横浜, Domestic conference

  Poster presentation


• 神経細胞におけるRNP顆粒の形成機構の解析

  吉田 篤史, 古川 真理, SAKAMOTO HIROSHI, INOUE KUNIO

  第39回日本分子生物学年会, Nov. 2016, Japanese, パシフィコ横浜, Domestic conference

  Poster presentation


• 始原生殖細胞の転写抑制状態の維持に関わるクロマチン制御機構の研究

  巳波 孝至, 高崎 輝恒, 井上 邦夫, 坂本 博

  関西地区線虫勉強会, Jun. 2016, Japanese, アプローズタワー 関西学院大学 梅田キャンパス, Domestic conference

  Oral presentation


• The nuclear RNA binding protein NONO is translocated to the cytoplasm during the neuronal differentiation, which is mediated through deSUMOylation of its specific region by SENP3 and SENP5

  Mari T. Furukawa, Kunio Inoue

  The 2016 joint annual meeting of the RNA Society and the RNA Society of Japan(RNA2016), Jun. 2016, English, Kyoto International Conference Center, International conference

  Poster presentation


• Chromodomain protein MRG-1 is required for global repression of Pol II-dependent transcription in the primordial germ cells in C. elegans

  Takashi Miwa, Teruaki Takasaki, Kunio Inoue, Hiroshi Sakamoto

  JSDB Special Symposium: Frontier of Developmental Biology Hosted by JSDB, Jun. 2016, English, 東京大学（東京都）, Domestic conference

  Poster presentation


• 網膜神経節細胞特異的RNA結合タンパク質HERMESはNonO、G3BP1などとともに神経RNA顆粒を形成する

  古川 真理, SAKAMOTO HIROSHI, INOUE KUNIO

  第38回日本分子生物学会, Dec. 2015, Japanese, 神戸国際展示場, Domestic conference

  Oral presentation


• 線虫C. elegansの生殖細胞形成に必須なクロマチン制御因子群の始原生殖細胞への限局機構の解析

  巳波 孝至, INOUE KUNIO, SAKAMOTO HIROSHI, TAKASAKI TERUAKI

  第38回日本分子生物学会, Dec. 2015, Japanese, 神戸国際展示場, Domestic conference

  Poster presentation


• 神経細胞におけるRNP顆粒の形成機構の解析

  吉田 篤史, 古川 真理, SAKAMOTO HIROSHI, INOUE KUNIO

  RNA Frontier Meeting 2015, Dec. 2015, Japanese, タカミヤヴィレッジホテル樹林, Domestic conference

  Oral presentation


• 神経細胞におけるRNP顆粒の形成機構の解析

  吉田 篤史, 古川 真理, SAKAMOTO HIROSHI, INOUE KUNIO

  第38回日本分子生物学会, Dec. 2015, Japanese, 神戸国際展示場, Domestic conference

  Poster presentation


• ゼブラフィッシュ卵母細胞のmRNA輸送機構の解析

  髙松 陽紀, SAKAMOTO HIROSHI, INOUE KUNIO

  第38回日本分子生物学会, Dec. 2015, Japanese, 神戸国際展示場, Domestic conference

  Poster presentation


• ゼブラフィッシュ初期胚におけるTob1aの母性mRNA制御機構の解析

  山畑 俊哉, SAKAMOTO HIROSHI, INOUE KUNIO

  第38回日本分子生物学会, Dec. 2015, Japanese, 神戸国際展示場, Domestic conference

  Poster presentation


• ゼブラフィッシュ初期胚でのTob1aによる母性mRNA制御機構の解析

  山畑 俊哉, SAKAMOTO HIROSHI, INOUE KUNIO

  RNA Frontier Meeting 2015, Dec. 2015, Japanese, タカミヤヴィレッジホテル樹林, Domestic conference

  Oral presentation


• 線虫C.elegansの始原生殖細胞成熟過程におけるクロマチン制御機構の研究

  巳波 孝至, TAKASAKI TERUAKI, INOUE KUNIO, SAKAMOTO HIROSHI

  関西地区線虫勉強会ジョイントミーティング, Oct. 2015, Japanese, 関西学院大学梅田キャンパス（大阪府）, Domestic conference

  Oral presentation


• Retinal ganglion cell-specific RNA binding protein HERMES forms the neuronal cytoplasmic RNA granules with NonO and G3BP1

  Mari T Furukawa, Kunio Inoue

  CSHL Meeting on Eukaryotic mRNA Processing, Aug. 2015, English, Cold Spring Harbor Laboratory（アメリカ）, International conference

  Poster presentation


• 網膜神経節細胞特異的RNA結合タンパク質HERMESはNonO,G3BP1などとともに神経RNA顆粒を形成する

  古川 真理, INOUE KUNIO

  第17回RNA学会年会, Jul. 2015, Japanese, ホテルライフォート札幌（北海道）, Domestic conference

  Oral presentation


• 線虫C.elegansの生殖細胞形成に必須なクロマチン制御因子群の始原生殖細胞への限局機構の解析

  巳波 孝至, TAKASAKI TERUAKI, INOUE KUNIO, SAKAMOTO HIROSHI

  第17回RNA学会年会, Jul. 2015, Japanese, ホテルライフォート札幌（北海道）, Domestic conference

  Oral presentation


• ゼブラフィッシュ生殖顆粒構成因子Dead-endにより発現制御を受けるmRNA群の同定

  小林 真奈美, INOUE KUNIO

  第17回RNA学会年会, Jul. 2015, Japanese, ホテルライフォート札幌（北海道）, Domestic conference

  Oral presentation


• Identification Of MRNAs Regulated By The Germ Granule Protein Dead-end In Zebrafish By RNA-seq.

  小林 真奈美, INOUE KUNIO

  Zebrafish 2015, Jun. 2015, English, Oslo Congress Centre, Norway, International conference

  Oral presentation


• Identification of mRNAs regulated by the germ granule protein Dead-end in zebrafish by RNA-seq

  小林 真奈美, INOUE KUNIO

  第48回日本発生生物学会, Jun. 2015, Japanese, つくば国際会議場, Domestic conference

  Poster presentation


• 網膜神経節細胞特異的RNA結合タンパク質HermesはNonOと細胞質でRNP顆粒を形成する

  古川 真理, INOUE KUNIO

  第37回日本分子生物学会, Nov. 2014, Japanese, パシフィコ横浜, Domestic conference

  Poster presentation


• 線虫C.elegansにおけるクロモドメイン蛋白質MRG-1の始原生殖細胞への限局メカニズムの解析

  巳波 孝至, INOUE KUNIO, SAKAMOTO HIROSHI, TAKASAKI TERUAKI

  第37回日本分子生物学会, Nov. 2014, Japanese, パシフィコ横浜, Domestic conference

  Poster presentation


• 線虫C.elegansにおけるRNAの輸送経路を決めるメカニズムの解析

  相澤 理丞, INOUE KUNIO, SAKAMOTO HIROSHI

  第37回日本分子生物学会, Nov. 2014, Japanese, パシフィコ横浜, Domestic conference

  Poster presentation


• ゼブラフィッシュ生殖顆粒構成因子Dead-endにより発現制御を受けるmRNA群の同定と機能解析

  小林 真奈美, INOUE KUNIO

  第37回日本分子生物学会, Nov. 2014, Japanese, パシフィコ横浜, Domestic conference

  Poster presentation


• ゼブラフィッシュ初期胚におけるTob1aの母性mRNA制御機構の解析

  山畑 俊哉, SAKAMOTO HIROSHI, INOUE KUNIO

  第37回日本分子生物学会, Nov. 2014, Japanese, パシフィコ横浜, Domestic conference

  Poster presentation


• TNRC6依存的なサイレンシングにおけるデキャッピング促進因子の機能

  牧野 志保, 三嶋 雄一郎, INOUE KUNIO, 稲田 利文

  第37回日本分子生物学会, Nov. 2014, Japanese, パシフィコ横浜, Domestic conference

  Poster presentation


• 線虫C.elegansにおける、クロモドメイン蛋白質MRG-1の始原生殖細胞への限局メカニズムの解析

  巳波 孝至, TAKASAKI TERUAKI, INOUE KUNIO, SAKAMOTO HIROSHI

  第5回サイエンスフロンティア研究発表会, Oct. 2014, Japanese, 神戸大学, Domestic conference

  Poster presentation


• 線虫C. elegansにおけるRNAの輸送経路を決める機構の解析

  相澤 理丞, INOUE KUNIO, SAKAMOTO HIROSHI

  関西地区線虫勉強会, Oct. 2014, Japanese, 関西学院大学梅田キャンパス, Domestic conference

  Oral presentation


• ゼブラフィッシュ初期胚におけるTob1aの母性mRNA制御機構の解析

  山畑 俊哉, SAKAMOTO HIROSHI, INOUE KUNIO

  第5回サイエンスフロンティア研究発表会, Oct. 2014, Japanese, 神戸大学, Domestic conference

  Poster presentation


• ゼブラフィッシュ生殖質構成因子の同定と機能解析

  小林 真奈美, 金村 節子, INOUE KUNIO

  RNAフロンティアミーティング2014, Sep. 2014, Japanese, ラフォーレ南紀白浜、和歌山県, Domestic conference

  Oral presentation


• ゼブラフィッシュ初期胚におけるTob1aの母性mRNA制御機構の解析

  山畑 俊哉, SAKAMOTO HIROSHI, INOUE KUNIO

  RNAフロンティアミーティング2014, Sep. 2014, Japanese, ラフォーレ南紀白浜、和歌山県, Domestic conference

  Oral presentation


• The mechanism for enrichment of a chromodomain protein MRG-1 into the primordial germ cells in C. elegans

  Takashi Miwa, Kunio Inoue, Hiroshi Sakamoto, Teruaki Takasaki

  C. elegans Development, Cell Biology and Gene Expression Meeting in Association with The 6th Asia-Pacific C. elegans Meeting, Jul. 2014, English, 奈良県新公会堂, International conference

  Poster presentation


• Analysis of the mechanism to enrich a chromodomain protein MRG-1 into the primordial germ cells in C.elegans

  Takashi Miwa, INOUE KUNIO, SAKAMOTO HIROSHI, TAKASAKI TERUAKI

  第47回日本発生生物学会, May 2014, Japanese, ウインクあいち、愛知県名古屋市, Domestic conference

  Oral presentation


• Developmental roles and evolution of the bicistronic microRNA precursor, miR-1/miR-133, expressed specifically in muscle tissues / 筋肉特異的microRNA前駆体miR-1/miR-133の機能と進化

  Rie Kusakabe, Saori Tani, Kunio Inoue

  第47回日本発生生物学会, May 2014, English, ウインクあいち、愛知県名古屋市, Domestic conference

  Oral presentation


• Analysis of the mechanism to enrich a chromodomain protein MRG-1 into the primordial germ cells in C. elegans

  Takashi Miwa, Kunio Inoue, Hiroshi Sakamoto, Teruaki Takasaki

  第47回日本発生生物学会, May 2014, English, ウインクあいち、愛知県名古屋市, Domestic conference

  Poster presentation


• 線虫C.elegans生殖細胞におけるスプライシング関連因子SPK-1の機能解析

  土橋 匠, TAKASAKI TERUAKI, INOUE KUNIO, SAKAMOTO HIROSHI

  関西地区線虫勉強会ジョイントミーティング, Oct. 2013, Japanese, 関西学院大学梅田キャンパス, Domestic conference

  Oral presentation


• ゼブラフィッシュ生殖質構成因子の機能解析

  小林 真奈美, INOUE KUNIO

  サイエンスフロンティア研究発表会, Oct. 2013, Japanese, 神戸大学, Domestic conference

  Oral presentation


• 線虫C.elegans生殖細胞におけるスプライシング関連タンパク質リン酸化酵素SPK-1の機能解析

  土橋 匠, TAKASAKI TERUAKI, INOUE KUNIO, SAKAMOTO HIROSHI

  RNAフロンティアミーティング2013, Sep. 2013, Japanese, ラフォーレ修善寺, Domestic conference

  Oral presentation


• 線虫C.elegansにおける生殖細胞形成に関与するクロマチンリモデリング因子群の局在機構の解析

  巳波 孝至, TAKASAKI TERUAKI, INOUE KUNIO, SAKAMOTO HIROSHI

  RNAフロンティアミーティング, Sep. 2013, Japanese, ラフォーレ修善寺, Domestic conference

  Oral presentation


• 線虫C.elegansにおけるRNAの輸送経路を決める機構の解析

  相澤 理丞, INOUE KUNIO, SAKAMOTO HIROSHI

  RNAフロンティアミーティング2013, Sep. 2013, Japanese, ラフォーレ修善寺, Domestic conference

  Oral presentation


• The regulatory mechanisms of apoptosis by Hermes, the retinal ganglion cell specific RNA binding protein

  Mari Furukawa, Kunio Inoue

  RNA Frontier Meeting 2013, Sep. 2013, English, ラフォーレ修善寺, Domestic conference

  Oral presentation


• The regulatory mechanism of apoptosis by Hermes, the retinal ganglion cell specific RNA binding protein

  Mari Furukawa, Kunio Inoue

  RiboClub, 14th annual meeting, Sep. 2013, English, Hotel Cheribourg, Quebec, Canada, International conference

  Poster presentation


• 網膜神経節細胞特異的RNA結合タンパク質Hermesによるアポトーシス制御機構の解析

  古川 真理, INOUE KUNIO

  第15回日本RNA学会年会, Jul. 2013, Japanese, 愛媛県県民文化会館ひめぎんホール, Domestic conference

  Oral presentation


• EVOLUTION OF REGULATORY MECHANISMS IN HYPAXIAL MUSCLE DEVELOPMENT

  Rie Kusakabe, Saori Tani, Richard, M. Harland, Kunio Inoue, Shigeru Kuratani

  10th International Congress of Vertebrate Morphology, Jul. 2013, English, Hotel Fira Palace, Barcelona, Spain, International conference

  Oral presentation


• The gene regulation in skeletal myogenesis in medaka, Oryzias latipes.

  Saori Tani, Rie Kusakabe, Kunio Inoue

  17th International Congress of Developmental Biology, Jun. 2013, English, Cancun,Mexico, International conference

  Oral presentation


• Roles of microRNAs in medaka myogenesis

  Saori Tani, Rie Kusakabe, Kunio Inoue

  第46回日本発生生物学会, May 2013, English, くにびきメッセ, Domestic conference

  Oral presentation


• Developmental evolution of the hypaxial muscles of vertebrates

  Rie Kusakabe, Saori Tani, Richard M. Harland, Shigeru Kuratani, Kunio Inoue

  第46回日本発生生物学会, May 2013, English, くにびきメッセ, Domestic conference

  Oral presentation


• 線虫EJC中核因子Y１４はスプライシング未完了RNAの核外輸送を防ぐ

  椎森 仁美, INOUE KUNIO, SAKAMOTO HIROSHI

  特定領域研究「RNA制御学」班会議, Jan. 2013, Japanese, レオパレス仙台, Domestic conference

  Oral presentation


• ゼブラフィッシュ生殖顆粒構成因子Granulitoタンパク質の機能解析

  稲川 陽介, 金村 節子, 三嶋 雄一郎, 柴田 英明, 前川 真吾, SAKAMOTO HIROSHI, INOUE KUNIO

  特定領域研究「RNA制御学」班会議, Jan. 2013, Japanese, レオパレス仙台, Domestic conference

  Poster presentation


• ゼブラフィッシュ胚発生を制御microRNAシステムの分子基盤

  三嶋雄一郎, 星島 一幸, David Grunwald, INOUE KUNIO

  第３５回分子生物学会年会・ワークショップ「RNA制御の細胞生物学」, Dec. 2012, Japanese, 福岡国際会議場, Domestic conference

  Oral presentation


• ゼブラフィッシュ生殖顆粒構成因子Granulitoタンパク質の機能解析

  稲川 陽介, 金村 節子, 三嶋 雄一郎, 柴田 英明, 前川 真吾, SAKAMOTO HIROSHI, INOUE KUNIO

  第35回分子生物学会年会, Dec. 2012, Japanese, 福岡国際会議場, Domestic conference

  Poster presentation


• RNA regulation in zebrafish germ cell formation.

  Inoue Kunio

  2012 Taiwan-Japan Joint Symposium on cell signaling and gene regulation., Nov. 2012, English, 国立成功大学、台南, International conference

  Invited oral presentation


• ゼブラフィッシュ生殖顆粒構成因子Granulitoタンパク質の機能解析

  稲川 陽介, 金村 節子, 三嶋 雄一郎, 前川 真吾, SAKAMOTO HIROSHI, INOUE KUNIO

  RNAフロンティアミーテイング2012, Sep. 2012, Japanese, メルパルク熊本, Domestic conference

  Poster presentation


• Exon Junction Complexは細胞周期関連遺伝子の効率的なpre-mRNAスプライシングに寄与する

  福村 和宏, 若林 俊一, 河村 有砂, SAKAMOTO HIROSHI, 鈴木 穣, 中井 謙太, INOUE KUNIO

  RNAフロンティアミーティング2012, Sep. 2012, Japanese, メルパルク熊本, Domestic conference

  Poster presentation


• 線虫EJC中核因子Y１４はスプライシング未完了RNAの核外輸送を防ぐ

  椎森 仁美, INOUE KUNIO, SAKAMOTO HIROSHI

  第14回日本RNA学会年会, Jul. 2012, Japanese, 東北大学百周年記念会館, Domestic conference

  Oral presentation


• Functional analysis of a germ granule component, Granulito, in the zebrafish germplasm

  稲川 陽介, 金村 節子, 三嶋 雄一郎, 前川 真吾, SAKAMOTO Hiroshi, INOUE Kunio

  第14回日本RNA学会年会, Jul. 2012, Japanese, 東北大学百周年記念会館, Domestic conference

  Poster presentation


• Molecular Mechanisms of MicroRNA-mediated Gene Silencing during Zebrafish Embryogenesis.

  Yuichiro Mishima, Kunio Inoue

  The 22nd CDB Meeting - RNA Sciences in Cell and Developmental Biology II, Jun. 2012, English, 理化学研究所CDB, International conference

  Oral presentation


• EJC core subunits have a novel gatekeeper function in mRNA quality control in the nematode C. elegans．

  Masami Shiimori, Kunio Inoue, Hiroshi Sakamoto

  The 22th CDB Meeting - RNA Sciences in Cell and Developmental Biology II, Jun. 2012, English, 理化学研究所CDB（神戸）, International conference

  Oral presentation


• 熱ストレスに応答した選択的スプライシング制御機構の解析

  河村 有砂, 山田 智子, FUKUMURA KAZUHIRO, 鈴木 仁, Vu, Luyen Thi, 塚原 俊文, SAKAMOTO Hiroshi, INOUE Kunio

  第34回日本分子生物学会年会, Dec. 2011, Japanese, 日本分子生物学会, 横浜, Domestic conference

  Poster presentation


• Molecular mechanisms and regulations of microRNA-mediated gene silencing in zebrafish

  MISHIMA Yuichiro, INOUE Kunio

  第34回日本分子生物学会年会, Dec. 2011, English, 日本分子生物学会, 横浜, Domestic conference

  Oral presentation


• Functional analysis of an RNP component, Granulito, in the zebrafish germplasm

  稲川 陽介, 金村 節子, MISHIMA Yuichiro, 前川 真吾, SAKAMOTO Hiroshi, INOUE Kunio

  第34回日本分子生物学会年会, Dec. 2011, English, 日本分子生物学会, 横浜, Domestic conference

  Poster presentation


• 選択的スプライシング制御とその破綻

  INOUE Kunio

  内分泌疾患談話会, Nov. 2011, Japanese, 群馬, Domestic conference

  Invited oral presentation


• Expression and function of muscle-specific microRNAs in medaka

  Saori Tani, Rie Kusakabe, Kiyoshi Naruse, Hiroshi Sakamoto, Kunio Inoue

  International Symposium Genetic Regulation of Development, Nov. 2011, English, 京都, Domestic conference

  Poster presentation


• 線虫Y14はイントロンを含む未スプライシングRNAの核外漏出を防ぐ

  椎森 仁美, FUKUMURA KAZUHIRO, 若林 俊一, 鈴木 穣, 中井 謙太, INOUE Kunio, SAKAMOTO Hiroshi

  第84回日本生化学会大会, Sep. 2011, Japanese, 日本生化学会, 京都, Domestic conference

  Invited oral presentation


• メダカの神経系発生過程におけるmiR-124の機能

  KATO Yumiko, KUSAKABE Rie, INOUE Kunio, TOCHINAI Shin

  第82回日本動物学会, Sep. 2011, Japanese, 日本動物学会, 旭川, Domestic conference

  Poster presentation


• Expression and function of muscle-specific microRNAs in medaka

  Saori Tani, Rie Kusakabe, Kiyoshi Naruse, Hiroshi Sakamoto, Kunio Inoue

  第17回小型魚類研究会, Sep. 2011, English, 小型魚類研究会, 三島, Domestic conference

  Oral presentation


• 線虫Y14はイントロンを含む未スプライシングRNAの核外輸送を防ぐ

  椎森 仁美, INOUE Kunio, SAKAMOTO Hiroshi

  RNAフロンティアミーティング2011, Aug. 2011, Japanese, 愛知, Domestic conference

  Oral presentation


• Two EJC core subunits, Y14 and MAG-1, have a novel gatekeeper function in mRNA quality control in the nematode C. elegans

  Masami Shiimori, Shunichi Wakabayashi, Yutaka Suzuki, Kenta Nakai, Kunio Inoue, Hiroshi Sakamoto

  RNA2011, Jun. 2011, English, The RNA Society, 日本RNA学会, 京都, Domestic conference

  Oral presentation


• Molecular mechanisms of miRNA-mediated repression during zebrafish embryogenesis

  Yuichiro Mishima, Akira Fukao, Tomoyoshi Kishimoto, Hiroshi Sakamoto, Toshinobu Fujiwara, Kunio Inoue

  RNA2011, Jun. 2011, English, The RNA Society, 日本RNA学会, 京都, Domestic conference

  Poster presentation


• Role of miR-124 in neural development of medaka, Oryzias latipesメダカの神経系発生過程におけるmiR-124の機能

  Yumiko Kato, Rie Kusakabe, Kunio Inoue, Shin Tochinai

  44th Annual Meeting for the Japanese Society of Developmental Biologists, May 2011, English, 日本発生生物学会, 沖縄, Domestic conference

  Poster presentation


• Developmental roles of muscle-specific microRNAs in medakaメダカ胚における筋肉特異的microRNAの発現と機能

  Saori Tani, Rie Kusakabe, Kiyoshi Naruse, Hiroshi Sakamoto, Kunio Inoue

  44th Annual Meeting for the Japanese Society of Developmental Biologists, May 2011, English, 日本発生生物学会, 沖縄, Domestic conference

  Oral presentation


• Molecular mechanisms of miRNA-mediated repression during zebrafish embryogenesis

  Yuichiro Mishima, Tomoyoshi Kishimoto, Akira Fukao, Hiroshi Sakamoto, Toshinobu Fujiwara, Kunio Inoue

  Keystone Symposia on Molecular and Cellular Biology “Mechanisms and Biology of RNA silencing, Mar. 2011, English, Keystone Symposia, California, USA, International conference

  Poster presentation


• 線虫C. elegansの生殖細胞性決定機構におけるY14の機能解析

  椎森 仁美, INOUE Kunio, SAKAMOTO Hiroshi

  第33回日本分子生物学会年会, Dec. 2010, Japanese, 日本分子生物学会, 神戸, Domestic conference

  Poster presentation


• メダカ胚における筋肉特異的microRNAの発現と機能

  TANI Saori, KUSAKABE Rie, NARUSE Kiyoshi, SAKAMOTO Hiroshi, INOUE Kunio

  第33回日本分子生物学会年会, Dec. 2010, Japanese, 日本分子生物学会, 神戸, Domestic conference

  Poster presentation


• miRISC中核因子であるTNRC6Aタンパク質によるポリＡ鎖短縮機構の解析

  岸本 友良, MISHIMA YUICHIRO, SAKAMOTO Hiroshi, INOUE Kunio

  第33回日本分子生物学会年会, Dec. 2010, Japanese, 日本分子生物学会, 神戸, Domestic conference

  Poster presentation


• microRNA経路の中核因子TNRC6Aは複数のメカニズムを介して標的mRNAを抑制する

  MISHIMA Yuichiro, 岸本 友良, 深尾 亜喜良, 武田 耕哲, SAKAMOTO Hiroshi, FUJIWARA Toshinobu, INOUE Kunio

  第33回日本分子生物学会年会, Dec. 2010, Japanese, 日本分子生物学会, 神戸, Domestic conference

  Oral presentation


• ゼブラフィッシュ生殖細胞形成に働くRNA情報発現制御システム

  INOUE Kunio

  北陸先端科学技術大学院大学マテリアルサイエンス研究科セミナー, Nov. 2010, Japanese, 北陸先端科学技術大学院大学マテリアルサイエンス研究科, 石川, Domestic conference

  Invited oral presentation


• メダカの神経系発生過程におけるmiR-124の機能

  KATO Yumiko, KUSAKABE Rie, INOUE Kunio, TOCHINAI Shin

  日本動物学会第81回大会, Sep. 2010, Japanese, 日本動物学会, 東京, Domestic conference

  Oral presentation


• カタユウレイボヤ脳胞におけるpiwiの新規機能の解析

  島井 光太郎, 一瀬 葵, 宮本 由紀, 寺島 泰子, 西辻 光希, 白江ー倉林, 麻, 中村 輝, KUSAKABE RIE, 中井 謙太, INOUE Kunio, 日下部 岳広

  日本動物学会第81回大会, Sep. 2010, Japanese, 日本動物学会, 東京, Domestic conference

  Oral presentation


• Functional interaction between the neuronal RNA-binding protein HuD and Akt1

  Akira Fukao, Yumi Sasano, Hiroaki Imataka, Kunio Inoue, Hiroshi Sakamoto, Nahum Sonenberg, Christian Thoma, Toshinobu Fujiwara

  TRANSLATIONAL CONTROL, Sep. 2010, English, CSHL, New York, USA, International conference

  Poster presentation


• microRNA経路の中核因子TNRC6Aは複数のメカニズムを介して標的mRNAを抑制する

  MISHIMA Yuichiro, 岸本 友良, 深尾 亜喜良, 武田 耕哲, SAKAMOTO Hiroshi, FUJIWARA TOSHINOBU, INOUE Kunio

  第2回RNAi研究会, Aug. 2010, Japanese, RNAi研究会, 広島, Domestic conference

  Oral presentation


• Control of germline/somatic cell distinction by miRNA function in zebrafish

  INOUE Kunio

  A satellite symposium on Germ Cells in SDB-JSDB Joint Meeting 2010, Aug. 2010, English, SDB, JSDB, New Mexico, USA, International conference

  Invited oral presentation


• 線虫C. elegansの生殖細胞性決定機構におけるY14の機能解析

  椎森 仁美, INOUE Kunio, SAKAMOTO Hiroshi

  第12回RNAミーティング（日本RNA学会年会）, Jul. 2010, Japanese, 日本RNA学会, 東京, Domestic conference

  Oral presentation


• 神経特異的RNA結合蛋白質HuDとシグナル伝達因子Aktとの連携による翻訳制御機構

  深尾 亜喜良, 笹野 有未, 今高 寛晃, INOUE Kunio, SAKAMOTO Hiroshi, Nahum Sonenberg, Christian Thoma, 藤原 俊伸

  第12回RNAミーティング（日本RNA学会年会）, Jul. 2010, Japanese, 日本RNA学会, 東京, Domestic conference

  Oral presentation


• Role of Y14 in C. elegans germline sexual differentiation

  椎森 仁美, INOUE Kunio, SAKAMOTO Hisroshi

  4th East Asia C. elegans Meeting, Jul. 2010, English, 東京, Domestic conference

  Poster presentation


• The Molecular Mechanisms of TNRC6 to Induce Translational Repression and Deadenylation in Zebrafish

  Yuichiro Mishima, Akira Fukao, Hiroshi Sakamoto, Toshinobu Fujiwara, Kunio Inoue

  The 19th CDB Meeting-RNA Sciences in Cell and Developmental Biology, May 2010, English, CDB, 神戸, Domestic conference

  Invited oral presentation


• Role of Y14 in C. elegans germline sexual differentiation

  椎森 仁美, INOUE Kunio, SAKAMOTO Hiroshi

  The 19th CDB Meeting-RNA Sciences in Cell and Developmental Biology, May 2010, English, CDB, 神戸, Domestic conference

  Poster presentation


• Genomic organization, expression and evolution of muscle-specific microRNAs

  Rie Kusakabe, Saori Tani, Shigehiro Kuraku, Yuki Miyamoto, Kohji Okamura, Kenta Nakai, Takehiro G. Kusakabe, Kunio Inoue

  The 19th CDB Meeting-RNA Sciences in Cell and Developmental Biology, May 2010, English, CDB, 神戸, Domestic conference

  Poster presentation


• メダカ初期胚におけるmiR-430の発現と機能

  TANI Saori, KUSAKABE Rie, NARUSE Kiyoshi, SAKAMOTO Hiroshi, INOUE Kunio

  第1回 甲南大学・モレキュラーサイエンスワークショップ, Mar. 2010, Japanese, 甲南大学, 神戸, Domestic conference

  [Invited]

  Invited oral presentation


• ゼブラフィッシュmiRNA制御システムによる生殖細胞・体細胞の分化機構

  INOUE Kunio

  第1回 甲南大学・モレキュラーサイエンスワークショップ, Mar. 2010, Japanese, 甲南大学, 神戸, Domestic conference

  Invited oral presentation


• The Molecular Mechanisms of TNRC6 to Induce Translational Repression and Deadenylation in Zebrafish

  Yuichiro Mishima, Akira Fukao, Hiroshi Sakamoto, Toshinobu Fujiwara, Kunio Inoue

  EMBL Conference: The complex life of mRNA: From synthesis to decay, Mar. 2010, English, EMBL, ドイツ, International conference

  Poster presentation


• RNAスプライシングによる形質発現制御機構

  INOUE Kunio

  第8回 神戸膠原病研究会, Mar. 2010, Japanese, 神戸膠原病研究会, 神戸, Domestic conference

  Invited oral presentation


• Control of germline/somatic cell distinctions by miRNA function

  INOUE Kunio

  The NIBB International Practical course “Developmental Genetics of zebrafish and medaka”, Jan. 2010, English, 基礎生物学研究所, 岡崎, Domestic conference

  Invited oral presentation


• メダカ初期胚におけるmiR-430の発現と機能

  TANI Saori, KUSAKABE Rie, NARUSE Kiyoshi, SAKAMOTO Hiroshi, INOUE Kunio

  第32回日本分子生物学会年会, Dec. 2009, Japanese, 日本分子生物学会, 神奈川, Domestic conference

  Poster presentation


• U1-independent splicing and the splicing regulation

  INOUE Kunio

  第32回日本分子生物学会年会, Dec. 2009, English, 日本分子生物学会, 神奈川, Domestic conference

  Invited oral presentation


• Role of Y14 in C. elegans germline sexual differentiation

  椎森 仁美, INOUE Kunio, SAKAMOTO Hiroshi

  第32回日本分子生物学会年会, Dec. 2009, English, 日本分子生物学会, 神奈川, Domestic conference

  Poster presentation


• Regulation of vertebrate gene expression by microRNAs

  Yuichiro Mishima, Antonio J. Giraldez, Kunio Inoue

  第32回日本分子生物学会年会, Dec. 2009, English, 日本分子生物学会, 神奈川, Domestic conference

  Invited oral presentation


• Role of Y14 in C. elegans germline sexual differentiation

  椎森 仁美, INOUE Kunio, SAKAMOTO Hiroshi

  2009Japan-Taiwan Joint Symposium on Cell Signaling and Gene Regulation, Nov. 2009, English, 神戸, International conference

  Poster presentation


• 線虫C. elegansの生殖細胞性決定機構におけるY14の機能解析

  椎森 仁美, INOUE Kunio, SAKAMOTO Hiroshi

  RNAフロンティアミーティング2009, Sep. 2009, Japanese, 神奈川, Domestic conference

  Oral presentation


• 筋肉ではたらくmicroRNAの機能と進化

  KUSAKABE Rie, 谷 沙織, 工樂 樹洋, 成瀬 清, 宮本 由紀, 岡村 浩司, 中井 健太, 日下部 岳広, INOUE Kunio

  第15回小型魚類研究会, Sep. 2009, Japanese, 小型魚類研究会, 名古屋, Domestic conference

  Oral presentation


• メダカ初期胚におけるmiR-430の発現と機能

  TANI Saori, KUSAKABE Rie, NARUSE Kiyoshi, SAKAMOTO Hiroshi, INOUE Kunio

  第15回小型魚類研究会, Sep. 2009, Japanese, 小型魚類研究会, 名古屋, Domestic conference

  Poster presentation


• Evolution of vertebrate myogenesis; with special reference to the morphological variety of skeletal muscles

  Rie Kusakabe, Shigehiro Kuraku, Shigeru Kuratani, Kunio Inoue

  International Society for Developmental Biology, Sep. 2009, English, ISDB, Edinburgh, International conference

  Poster presentation


• Enhancement of cap-dependent translation by the ELAV protein HuD: A novel function of HuD which is eIF4A- and poly(A)-dependent

  Akira Fukao, Yumi Sasano, Hiroaki Imataka, Kunio Inoue, Hiroshi Sakamoto, Nahum Sonenberg, Christian Thoma, Toshinobu Fujiwara

  Protein Synthesis and Translational Control, Sep. 2009, English, EMBL, Heidelberg, Germany, International conference

  Oral presentation


• 線虫C. elegansの生殖細胞性決定機構におけるY14の機能解析

  椎森 仁美, INOUE Kunio, SAKAMOTO Hiroshi

  第11回 RNAミーティング, Jul. 2009, Japanese, 日本RNA学会, 新潟, Domestic conference

  Poster presentation


• Zebrafish Dazl ensures PGC specific gene expression through blocking the miRNA-mediated gene silencing

  Yasuaki Takeda, Yuichiro Mishima, Hiroshi Sakamoto, Kunio Inoue

  6th European Zebrafish Genetics and Development Meeting, Jul. 2009, English, Rome, Italy, International conference

  Poster presentation


• poly(A)配列およびeIF4Aを介したELAV蛋白質HuDによるcap依存的翻訳促進機構

  FUKAO Akira, SASANO Yumi, IMATAKA Hiroaki, INOUE Kunio, SAKAMOTO Hiroshi, Nahum Sonenberg, Christian Thoma, FUJIWARA Toshinobu

  第11回 RNAミーティング, Jul. 2009, Japanese, 日本RNA学会, 新潟, Domestic conference

  Oral presentation


• Genomic organization and developmental expression of tunicate microRNAs

  谷 沙織, KUSAKABE Rie, 宮本 由紀, 岡村 浩司, 中井 健太, 日下部 岳広, INOUE Kunio

  The 5th International Tunicate meeting, Jun. 2009, English, 沖縄, Domestic conference

  [Invited]

  Invited oral presentation


• Functional analysis of Y14 in C. elegans germline sexual differentiation

  椎森 仁美, 郷原 美里, 笹野 有未, INOUE Kunio, SAKAMOTO Hiroshi

  第42回日本発生生物学会大会, May 2009, English, 日本発生生物学会, 新潟, Domestic conference

  Poster presentation


• Evolution and developmental expression of chordate microRNAs

  Rie Kusakabe, Saori Tani, Shigehiro Kuraku, Yuki Miyamoto, Kohji Okamura, Kenta Nakai, Takehiro G. Kusakabe, Kunio Inoue

  第42回日本発生生物学会大会, May 2009, English, 日本発生生物学会, 新潟, Domestic conference

  Oral presentation


• Embryonic expression and function of miR-430 in medaka

  Saori Tani, Rie Kusakabe, Kiyoshi Naruse, Hiroshi Sakamoto, Kunio Inoue

  第42回日本発生生物学会大会, May 2009, English, 日本発生生物学会, 新潟, Domestic conference

  Oral presentation


• ゼブラフィッシュGerm plasm RNAの局在化機構の解析

  森 さやか, SAKAMOTO Hiroshi, INOUE Kunio

  第31回日本分子生物学会年会、第81回生化学会大会, Dec. 2008, Japanese, 日本分子生物学会, 神戸, Domestic conference

  Poster presentation


• U1snRNP非依存的pre-mRNAスプライシングは選択的スプライシング制御に寄与する

  福村 和宏, 谷口 一郎, 新名主 カオリ, SAKAMOTO Hiroshi, 大野 睦人, INOUE Kunio

  第31回日本分子生物学会年会、第81回生化学会大会, Dec. 2008, Japanese, 日本分子生物学会, 神戸, Domestic conference

  Oral presentation


• U1-independent pre-mRNA splicing contributes to the regulation of alternative splicing

  INOUE Kunio

  東京医科歯科大学難治疾患研究所病態発現機構研究部門主催国際シンポジウム, Dec. 2008, English, 東京医科歯科大学難治疾患研究所病態発現機構研究部門, 東京, Domestic conference

  Invited oral presentation


• DAZLによるPGC特異的遺伝子-TDRD7に働くmiRNA機能の解除

  武田 耕哲, MISHIMA Yuichiro, FUJIWARA Toshinobu, SAKAMOTO Hiroshi, INOUE Kunio

  第31回日本分子生物学会年会、第81回生化学会大会, Dec. 2008, Japanese, 日本分子生物学会, 神戸, Domestic conference

  Oral presentation


• NEURONAL HUD PROTEINS ASSOCIATE WITH EIF4F AND DIRECTLY RECRUIT CATALYTICALLY ACTIVE AKT1 TO INDUCE NEURONAL DIFFERENTIATION

  Akira Fukao, Christian Thoma, Kunio Inoue, Hiroaki Imataka, Nahum Sonenberg, Hiroshi Sakamoto, Toshinobu Fujiwara

  TRANSLATIONAL CONTROL, Sep. 2008, English, CSHL, New York, USA, International conference

  Poster presentation


• ゼブラフィッシュ生殖細胞形成とRNA生物学

  INOUE Kunio

  第3回生殖研究ワークショップ, Aug. 2008, Japanese, 神奈川, Domestic conference

  Invited oral presentation


• U1 snRNP非依存的pre-mRNAスプライシング分子機構の研究

  福村 和宏, 谷口 一郎, 新名主 カオリ, SAKAMOTO Hiroshi, 大野 睦人, INOUE Kunio

  第10回日本RNA学会年会, Jul. 2008, Japanese, 日本RNA学会, 北海道, Domestic conference

  Oral presentation


• The mechanism blocking the miRNA-mediated silencing of PGC-specific TDRD7 gene in zebrafish

  Yasuaki Takeda, Yuichiro Mishima, Hiroshi Sakamoto, Kunio Inoue

  13th Annual Meeting of the RNA Society, Jul. 2008, English, The RNA Society, Berlin,Germany, International conference

  Poster presentation


• Differential gene expression of muscle-related genes in the lamprey and teleosts

  Rie Kusakabe, Shigehiro Kuraku, Kunio Inoue, Shigeru Kuratani

  The second meeting of European Society for Evolutionary Developmental Biology, Jul. 2008, English, Gent,Belgium, International conference

  Oral presentation


• 線虫C. elegansの生殖細胞性決定機構におけるY14の機能解析

  椎森 仁美, 笹野 有未, 郷原 美里, INOUE Kunio, SAKAMOTO Hiroshi

  RNAフロンティアミーティング2008, Jun. 2008, Japanese, 京都, Domestic conference

  Oral presentation


• 神経特異的RNA結合タンパク質HuDによる翻訳制御機構

  FUKAO Akira, IMATAKA Hiroaki, INOUE Kunio, Nahum Sonenberg, SAKAMOTO Hiroshi, FUJIWARA Toshinobu

  RNAフロンティアミーティング2008, Jun. 2008, Japanese, 京都, Domestic conference

  Oral presentation


• U1に依存しないスプライシングによる制御機構

  INOUE Kunio

  東京医科歯科大学大学院疾患生命科学研究部・形質発現セミナー, Jun. 2008, Japanese, 東京医科歯科大学大学院疾患生命科学研究部, 東京, Domestic conference

  Invited oral presentation


• U1に依存しないスプライシングによる制御機構

  INOUE Kunio

  京都大学ウイルス研究所セミナー, Jun. 2008, Japanese, 京都大学ウイルス研究所, 京都, Domestic conference

  Invited oral presentation


• ゼブラフィッシュ生殖細胞遺伝子TDRD7のmiRNAによる抑制はDazlによって解除される

  武田 耕哲, MISHIMA Yuichiro, SAKAMOTO Hiroshi, INOUE Kunio

  第41回日本発生生物学会・サテライトワークショップ「多分野で活躍する小型魚類」, May 2008, Japanese, 日本発生生物学会, 徳島, Domestic conference

  Poster presentation


• ゼブラフィッシュmiRNA制御システムによる生殖細 胞形成機構

  INOUE Kunio

  第41回日本発生生物学会・サテライトワークショップ「多分野で活躍する小型魚類」, May 2008, Japanese, 日本発生生物学会, 徳島, Domestic conference

  Invited oral presentation


• Differential expression and molecular interaction of regulatory genes in vertebrate myogenesis脊椎動物の骨格筋発生過程における遺伝子制御機構

  Rie Kusakabe, Shigehiro Kuraku, Kunio Inoue, Shigeru Kuratani

  第41回日本発生生物学会・サテライトワークショップ「多分野で活躍する小型魚類」, May 2008, English, 日本発生生物学会, 徳島, Domestic conference

  Poster presentation


• Molecular mechanism of alternative splicing regulation by RNA binding protein Fox-1

  福村 和宏, 加藤 彩子, 神 唯, FUJIWARA TOSHINOBU, SAKAMOTO Hiroshi, INOUE Kunio

  日本分子生物学会・日本生化学会, Dec. 2007, English, 日本分子生物学会, 横浜, Domestic conference

  Invited oral presentation


• miRNA制御システムによる生殖細胞・体細胞分化確立機構

  INOUE Kunio

  日本分子生物学会・日本生化学会, Dec. 2007, Japanese, 日本分子生物学会, 横浜, Domestic conference

  Invited oral presentation


• ゼブラフィッシュ生殖細胞形成過程に働くRNAプログラム

  INOUE Kunio

  日本発生生物学会 秋季シンポジウム, Nov. 2007, Japanese, 日本発生生物学会, 岡崎, Domestic conference

  Invited oral presentation


• 小さなRNAの大きな役割～microRNAによるゼブラフィッシュ初期発生 調節機構～

  INOUE Kunio

  和光純薬セミナー, Oct. 2007, Japanese, 和光純薬, 大阪, Domestic conference

  Invited oral presentation


• ゼブラフィッシュGermplasm RNAの局在化機構の解析

  森 さやか, 小坂 恭子, SAKAMOTO Hiroshi, INOUE Kunio

  RNA研究若手の会, Sep. 2007, Japanese, 神戸, Domestic conference

  Oral presentation


• Neuronal RNA binding protein HuD interact with protein kinase B

  FUKAO Akira, TAKEUCHI Akiko, FUJIWARA Toshinobu, MATSUZAKI Hidenori, INOUE Kunio, KIKKAWA Ushio, SAKAMOTO Hiroshi

  EMBO Conference on Protein Synthesis and Translational Control, Sep. 2007, English, European Molecular Biology Laboratory, Heidelberg, Germany, International conference

  Poster presentation


• 小さなRNAの大きな役割〜microRNAによるゼブラフィッシュ初期発生調節機構 〜

  INOUE Kunio

  第5回最先端動物遺伝育種セミナー, Aug. 2007, Japanese, 日本動物遺伝育種学会, 山梨, Domestic conference

  Invited oral presentation


• ゼブラフィッシュ生殖細胞形成過程に働くRNAプログラム

  INOUE Kunio

  第9回日本RNA学会年会, Jul. 2007, Japanese, 日本RNA学会, 名古屋, Domestic conference

  Invited oral presentation


• ゼブラフィッシュ生殖細胞形成過程に働くRNAプログラム

  INOUE Kunio

  2007年度国立遺伝学研究所研究会「生殖細胞と生殖腺形成の普遍性と多様性」, Jul. 2007, Japanese, 国立遺伝学研究所, 三島, Domestic conference

  Invited oral presentation


• Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430

  Yuichiro Mishima, Antonio J. Giraldez, Yasuaki Takeda, Toshinobu Fujiwara, Hiroshi Sakamoto, Alexander F. Schier, Kunio Inoue

  The 5th European Zebrafish Genetics and Development Meeting, Jul. 2007, English, Amesterdam, International conference

  Poster presentation


• Regulation of tissue specific splicing by RNA binding protein Fox-1

  Kazuhiro Fukumura, Ayako Kato, Yui Jin, Toshinobu Fujiwara, Hiroshi Sakamoto, Kunio Inoue

  第40回発生生物学会・第59回日本細胞生物学会, May 2007, English, 日本発生生物学会, 福岡, Domestic conference

  Poster presentation


• Regulation of PGC-specific gene TDRD7 by zebrafish miR-430

  Yasuaki Takeda, Yuichiro Mishima, Hiroshi Sakamoto, Kunio Inoue

  第40回発生生物学会・第59回日本細胞生物学会, May 2007, English, 日本発生生物学会, 福岡, Domestic conference

  Poster presentation


• Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430

  INOUE Kunio

  第40回発生生物学会・第59回日本細胞生物学会, May 2007, English, 日本発生生物学会, 福岡, Domestic conference

  Invited oral presentation


• Regulation of tissue specific splicing by RNA binding protein Fox-1

  Kazuhiro Fukumura, Ayako Kato, Yui Jin, Toshinobu Fujiwara, Hiroshi Sakamoto, Kunio Inoue

  日本分子生物学会第7回春季シンポジウム, Apr. 2007, English, 日本分子生物学会, 淡路, Domestic conference

  Poster presentation


• Neuronal RNA binding protein HuD interact with protein kinase B

  FUKAO Akira, FUJIWARA Toshinobu, MATSUZAKI Hidenori, INOUE Kunio, KIKKAWA Ushio, SAKAMOTO Hiroshi

  The 7th MBSJ Spring Symposium, Apr. 2007, English, 日本分子生物学会, 神戸市, International conference

  Poster presentation


• Mechanism of pre-ribosomal RNA processing in Caenorhabditis elegans

  SASANO Yumi, HOKII Yusuke, USHIDA Chisato, INOUE Kunio, SAKAMOTO Hiroshi, FUJIWARA Toshinobu

  The 7th MBSJ Spring Symposium, Apr. 2007, English, 日本分子生物学会, 神戸市, International conference

  Poster presentation


• miRNA制御システムによる生殖細胞・体細胞分化確立機構

  井上 邦夫

  日本分子生物学会2006フォーラム, Dec. 2006, Japanese, 名古屋, Domestic conference

  Invited oral presentation


• RNAプログラムによる生殖細胞形成機構

  井上 邦夫

  第17回フォーラム・イン・ドージン, Nov. 2006, Japanese, 熊本, Domestic conference

  Invited oral presentation


• Fox蛋白質によるスプライシング制御機構

  井上 邦夫

  第2回 神戸スプライシングカンファレンス, Nov. 2006, Japanese, 神戸, Domestic conference

  Invited oral presentation


• Regulation of tissue-specific splicing by Fox protein

  井上 邦夫

  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress, Jun. 2006, English, 京都, Domestic conference

  Invited oral presentation


• リボソ-ムの異常と疾患 ～ゼブラフィッシュを用いた解析.

  UECHI Tamayo, NAKASHIMA Yukari, MISHIMA Yuichiro, INOUE Kunio, KENMOCHI Naoya

  第28回日本分子生物学会年会, Dec. 2005, Japanese, 福岡, Domestic conference

  Oral presentation


• Control of maternal mRNA localization required for germ cell formation in zebrafish.

  KOSAKA Kyoko, UEDA Yasunori, MISHIMA Yuichiro, KAWAKAMI Koichi, SAKAMOTO Hiroshi, INOUE Kunio

  COE日台国際シンポジウム, Nov. 2005, Japanese, 神戸大学, Domestic conference

  Oral presentation


• Zebrafish nanos1 3'UTR represses translation in somatic cells by accelerating deadenylation.

  MISHIMA Yuichiro, FUJIWARA Toshinobu, SKAMOTO Hiroshi, INOUE Kunio

  COE日台国際シンポジウム, Oct. 2005, Japanese, 神戸大学, Domestic conference

  Oral presentation


• Zebrafish nanos1 3'UTR represses translation in somatic cells by accelerating deadenylation.

  MISHIMA Yuichiro, SAKAMOTO Hiroshi, INOUE Kunio

  第十一回小型魚類研究集会, Sep. 2005, Japanese, 岡崎, Domestic conference

  Oral presentation


• Evidence for the involvement of neuron-specific Hu proteins in the translational regulation.

  TAKEUCHI Setsuko, WADA, FUJIWARA Toshinobu, INOUE Kunio, SAKAMOTO Hiroshi

  EMBO Conference on Protein Synthesis and Translational Control, Sep. 2005, English, ドイツ, International conference

  Oral presentation


• Bruno-like protein is localized to germ plasm during early cleavage stages in zebrafish.

  HASIMOTO Y, SUZUKI H, KAGEYAMA Y, YASUDA K, INOUE Kunio

  15th International Society of Developmental Biologists Congress, Sep. 2005, English, オ-ストラリア, International conference

  Oral presentation


• ゼブラフィッシュを用いたリボソームタンパク質の機能解析.

  UECHI Tamayo, NAKASHIMA Yukari, MISHIMA Yuichiro, INOUE Kunio, KENMOCHI Naoya

  第7回RNAミ-ティング（日本RNA学会年会）, Aug. 2005, Japanese, 弘前大学, Domestic conference

  Oral presentation


• Regulation of alternative splicing by Fox-1 via binding to GCAUG sequence upstream of alternative exon.

  FUKUMURA Kazuhiro, JIN Yui, KATO Atako, FUJIWARA Toshinobu, SAKAMOTO Hiroshi, INOUE Kunio

  Cold Spring Harbor Laboratory Meeting EUKARYOTIC mRNA PROCESSING, Aug. 2005, English, アメリカ, International conference

  Oral presentation


• Control of nanos1 mRNA stability during PGC formation in zebrafish.

  MISHIMA Yuichiro, FUJIWARA Toshinobu, SAKAMOTO Hiroshi, INOUE Kunio

  4th European Zebrafish genetics and Development Meeting, Jul. 2005, English, ドイツ, International conference

  Oral presentation


• ゼブラフィッシュ生殖細胞形成過程にはたらく母性mRNA局在化機構の解析

  KOSAKA Kyoko, UEDA Yasunori, MISHIMA Yuichiro, KAWAKAMI Koichi, SAKAMOTO Hiroshi, INOUE Kunio

  日本発生生物学会第38回大会, Jun. 2005, Japanese, 仙台, Domestic conference

  Oral presentation


• MRG-1, A C. ELEGANS CHROMODOMAIN PROTEIN IS ESSENTIAL FOR PROPER GENE EXPRESSION IN THE PRIMORDIAL GERM CELLS.

  TAKASAKI Teruaki, HABARA Yasuaki, NISHIWAKI Kiyoji, FUJIWARA Toshinobu, NAKAYAMA Jun-ichi, INOUE Kunio, SAKAMOTO Hiroshi

  15th Biennial International C.elegans conference, Jun. 2005, English, アメリカ, International conference

  Oral presentation


• Control of maternal mRNA localization required for germ cell formation in zebrafish.

  KOSAKA Kyoko, UEDA Yasunori, MISHIMA Yuichiro, KAWAKAMI Koichi, SAKAMOTO Hiroshi, INOUE Kunio

  FASEB Summer Research Conferences「Intracellular RNA Sorting, Transport & Localization」, Jun. 2005, English, アメリカ, International conference

  Oral presentation


• ゼブラフィッシュ生殖細胞形成機構の分子発生生物学的解析.

  INOUE Kunio

  基礎生物学研究所研究会「小型魚類のさらなる発展を求めて」, May 2005, Japanese, 岡崎, Domestic conference

  Oral presentation


• RNA結合タンパク質Fox-1による選択的スプライシング制御機構の解析.

  FUKUMURA Kazuhiro, FUJIWARA Tochinobu, SAKAMOTO Hiroshi, INOUE Kunio

  特定領域研究「RNA情報網」第3回サテライトミーティング『RNA情報発現系の仕組みと制御』, May 2005, Japanese, 三重県, Domestic conference

  Oral presentation


• Regulation of 18S ribosomal RNA processing in Caenorhabditis elegans.

  SASANO Yumi, FUJIWARA Toshinobu, INOUE Kunio, SAKAMOTO Hiroshi

  The Tenth Annual Meeting of the RNA society, May 2005, English, カナダ, International conference

  Oral presentation


• ゼブラフィッシュ生殖細胞形成過程に働くRNA－蛋白質複合体

  井上 邦夫

  日本分子生物学会第27回年会, Dec. 2004, Japanese, 日本分子生物学会, 神戸ポートアイランド, Domestic conference

  Others


• ゼブラフィッシュにおける母性mRNA局在化機構の解析

  小坂 恭子, 三嶋 雄一郎, 川上 浩一, 坂本 博, 井上 邦夫

  第6回RNAミーティング, Aug. 2004, Japanese, 未記入, 熊本テルサ, Domestic conference

  Oral presentation


• ゼブラフィッシュを用いたDaz遺伝子の機能解析

  三嶋 雄一郎, 前川 真吾, 坂本 博, 井上 邦夫

  日本発生生物学会第37回大会, Jun. 2004, Japanese, 日本発生生物学会, 名古屋国際会議場, Domestic conference

  Poster presentation


• ゼブラフィッシュにおける母性mRNA局在化機構の解析

  小坂 恭子, 三嶋 雄一郎, 川上 浩一, 坂本 博, 井上 邦夫

  日本発生生物学会第37回大会, Jun. 2004, Japanese, 日本発生生物学会, 名古屋国際会議場, Domestic conference

  Oral presentation


• ゼブラフィッシュにおける母性mRNA局在化機構の解析

  小坂 恭子, 三嶋 雄一郎, 川上 浩一, 坂本 博, 井上 邦夫

  第37回日本発生生物学会, Jun. 2004, Japanese, 日本発生生物学会, 名古屋国際会議場, Domestic conference

  Poster presentation


• ゼブラフィッシュにおけるリボソーム変異モデルの作製

  上地 珠代, 三嶋 雄一郎, 井上 邦夫, 剣持 直哉

  第6回日本RNA学会年会, Jun. 2004, Japanese, 日本RNA学会, 熊本テルサ, Domestic conference

  Poster presentation


• ゼブラフィッシュ生殖細胞形成における母性供与因子群の役割

  橋本 祥子, 前川 真吾, 鈴木 仁, 安田 國雄, 井上 邦夫

  日本分子生物学会春季シンポジウム, May 2004, Japanese, 日本分子生物学会, 奈良県新公会堂, Domestic conference

  Others


• ゼブラフィッシュ生殖細胞に存在するRNPの解析

  三嶋 雄一郎, 前川 真吾, 鈴木 仁, 橋本 祥子, 坂本 博, 井上 邦夫

  RNA研究若手の会2004「高次生命現象におけるRNA制御」, May 2004, Japanese, 未記入, 淡路夢舞台国際会議場, Domestic conference

  Others


• ゼブラフィッシュにおける母性mRNA局在化機構の解析

  小坂 恭子, 三嶋 雄一郎, 川上 浩一, 坂本 博, 井上 邦夫

  RNA研究若手の会2004「高次生命現象におけるRNA制御」, May 2004, Japanese, 未記入, 淡路夢舞台国際会議場, Domestic conference

  Others


• Functional analysis of zebrafish DAZL protein during germ cell formation.

  MISHIMA Y, SAKAMOTO Hiroshi, INOUE Kunio

  Conference on lipid messenger signaling , The first COE International Meeting., Jan. 2004, English, 未記入, Kobe, Domestic conference

  Oral presentation


• 神経特異的Hu蛋白質の機能解析

  斎藤 都暁, 藤原 俊伸, 井上 邦夫, 坂本 博

  第26回日本分子生物学会, Dec. 2003, Japanese, 日本分子生物学会, 神戸ポートアイランド、神戸市, Domestic conference

  Oral presentation


• ゼブラフィッシュにおけるリボソームタンパク質遺伝子の発現抑制

  上地 珠代, 橋本 祥子, 井上 邦夫, 剣持 直哉

  第26回日本分子生物学会, Dec. 2003, Japanese, 日本分子生物学会, 神戸ポートアイランド、神戸市, Domestic conference

  Poster presentation


• ゼブラフィッシュPGC形成過程におけるzDazlの機能解析

  三嶋 雄一郎, 前川 真吾, 藤原 俊伸, 坂本 博, 井上 邦夫

  第26回日本分子生物学会, Dec. 2003, Japanese, 日本分子生物学会, 神戸ポートアイランド、神戸市, Domestic conference

  Poster presentation


• Fox-1による選択的スプライシング制御機構の解析

  神 唯, 鈴木 仁, 前川 真吾, 遠藤 仁司, 安田 國雄, 坂本 博, 井上 邦夫

  第26回日本分子生物学会, Dec. 2003, Japanese, 日本分子生物学会, 神戸ポートアイランド、神戸市, Domestic conference

  Oral presentation


• Ribosomal protein gene knockdown using the antisense oligos in zebrafish.

  上地 珠代, 橋本 祥子, 井上 邦夫, 剣持 直哉

  国際シンポジウム ”The New Frontier of RNA science”, Nov. 2003, English, 未記入, 国立京都国際会館, Domestic conference

  Poster presentation


• Microubule association of a neuronal RNA-binding protein HuD through its binding to the light chain of MAP1B.

  斎藤 都暁, 藤原 俊伸, 笠島 克巳, 井上 邦夫, 坂本 博

  国際シンポジウム ”The New Frontier of RNA science”, Nov. 2003, English, 未記入, 国立京都国際会館, Domestic conference

  Oral presentation


• Functional analysis of zDazl protein during PGC formation in zebrafish.

  三嶋 雄一郎, 前川 真吾, 藤原 俊伸, 坂本 博, 井上 邦夫

  国際シンポジウム ”The New Frontier of RNA science”, Nov. 2003, English, 未記入, 国立京都国際会館, Domestic conference

  Poster presentation


• Fox-1 functions as both positive and negative regulator of alternative splicing in vertebrates.

  神 唯, 安田 國雄, 坂本 博, 井上 邦夫

  国際シンポジウム ”The New Frontier of RNA science”, Nov. 2003, English, 未記入, 国立京都国際会館, Domestic conference

  Poster presentation


• ゼブラフィッシュ生殖細胞形成過程に働くRNA情報発現制御機能

  三嶋 雄一郎, 前川 真吾, 坂本 博, 井上 邦夫

  第9回小型魚類研究集会, Sep. 2003, Japanese, 未記入, 理化学研究所、和光市, Domestic conference

  Oral presentation


• ゼブラフィッシュにおける母性ｍRNA局在化機構の解明

  小坂 恭子, 橋本 祥子, 前川 真吾, 安田 國雄, 坂本 博, 井上 邦夫

  第9回小型魚類研究集会, Sep. 2003, Japanese, 未記入, 理化学研究所、和光市, Domestic conference

  Poster presentation


• Fox-1 functions as both positive and negative regulator of alternative splicing in vertebrates.

  神 唯, 安田 國雄, 坂本 博, 井上 邦夫

  Eukaryotic mRNA processing meeting, Aug. 2003, English, 未記入, CSHL, ニューヨーク, International conference

  Poster presentation


• Requirement of localized Maternal Factors for Zebrafish Germ Cell Formation

  橋本 祥子, 前川 真吾, 安田 國雄, 井上 邦夫

  Society for Developmental Biology 62nd Annual Meeting Jointly with the International Society of Developmental Biology, Jul. 2003, English, Society for Developmental Biology, Marriott Copley Place, ボストン, International conference

  Poster presentation


• Fox-1による選択的スプライシング制御機能の解析

  神 唯, 坂本 博, 井上 邦夫

  RNA研究者若手の会2003「真核生物におけるmRNA情報発現」, Jul. 2003, Japanese, RNA研究者若手の会, ウェルサンピア滋賀, Domestic conference

  Others


• 異時的に移植されたゼブラフィッシュ始原生殖細胞（PGCs）の移動および分化

  長井 輝美, 斎藤 大輝, 吉川 智仁, 大谷 哲, 前川 真吾, 井上 邦夫, 荒井 克俊, 山羽 悦郎

  日本水産学会, Apr. 2003, Japanese, 日本水産学会, 東京水産大学, Domestic conference

  Oral presentation

• 日本RNA学会


• 日本発生生物学会


• 日本分子生物学会

• 熱ストレスに応答した選択的スプライシング機構の研究

  井上 邦夫, 松花 沙織

  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Kobe University, Apr. 2021 - Mar. 2024, Principal investigator


• ゲノム情報正常発現を保証するスプライシング未完了RNAの核内繋留機構

  坂本 博

  科学研究費補助金／基盤研究(B), Apr. 2014 - Mar. 2017

  Competitive research funding


• 母性プログラムにおけるmRNA前駆体スプライシング制御の役割

  井上 邦夫

  学術研究助成基金助成金／挑戦的萌芽研究, Apr. 2014 - Mar. 2016, Principal investigator

  Competitive research funding


• 細胞質の生殖顆粒による核内ゲノム情報発現制御機構

  井上 邦夫

  科学研究費一部基金／基盤研究(B)特設, Apr. 2013 - Mar. 2016, Principal investigator

  Competitive research funding


• 選択的スプライシング制御を介した熱ストレス応答機構

  井上 邦夫

  科学研究費補助金／萌芽研究, Apr. 2012 - Mar. 2014, Principal investigator

  Competitive research funding


• 異常スプライシングＲＮＡの網羅的同定とその意義の解明

  坂本 博

  学術研究助成基金助成金／基盤研究(C), 2011

  Competitive research funding


• ｍＲＮＡ制御システムによる生殖細胞形成機構

  井上 邦夫

  科学研究費補助金／新学術領域研究, 2009, Principal investigator

  Competitive research funding


• Ｕ１に依存しない新規スプライシング機構の解明

  井上 邦夫

  科学研究費補助金／基盤研究(C), 2009, Principal investigator

  Competitive research funding


• ｍｉｃｒｏＲＮＡ制御システムによる生殖細胞・体細胞分化確立機構

  井上 邦夫

  科学研究費補助金／基盤研究(B), 2007, Principal investigator

  Competitive research funding


• ｍＲＮＡ局在化の制御機構

  井上 邦夫

  科学研究費補助金／特定領域研究, 2005, Principal investigator

  Competitive research funding


• 人口設計した短鎖RNAによる組織特異的な遺伝子発現抑制システムの構築

  井上 邦夫

  科学研究費補助金／萌芽研究, 2005, Principal investigator

  Competitive research funding