SEARCH
検索詳細
菅 彩香大学院保健学研究科 保健学専攻助教
研究活動情報
■ 論文- Abstract Pancreatic cancer is a malignant tumor that metastasizes to distant organs, such as the liver and lungs from an early stage. Few animal models can reproduce early metastasis. In addition, no model has been reported that reproduces cancer-related hypercoagulability, which is characteristic of pancreatic ductal adenocarcinoma and other adenocarcinomas. We hypothesized that the reason why the commonly used orthotopic cell xenograft model cannot reproduce the disease is inadequate construction of the cancer microenvironment. We developed an orthotopic tissue fragment xenograft model in which tumor tissue was transplanted into the pancreas of mice while preserving the microenvironment. Briefly, we injected single cancer cells subcutaneously to form a tumor, which was then cut with a scalpel into tumor fragments. A fragment was then sutured and fixed to the surface of the pancreatic tail. In this study, we evaluated the superiority of this model over a conventional orthotopic cell xenograft model. As a result, the novel orthotopic tissue xenograft model reproduced early distant metastasis to the liver and lung, nerve invasion, and cancer-related hypercoagulability of human pancreatic cancer, and showed greater similarity to clinical cases than the control orthotopic cell xenograft model.Springer Science and Business Media LLC, 2025年03月, Medical Molecular Morphology, 英語[査読有り]研究論文（学術雑誌）
- Springer Science and Business Media LLC, 2024年12月, Cureus, 16(12) (12), 英語[査読有り]研究論文（学術雑誌）
- 2024年10月, Health Communication Research, 15(2) (2), 18 - 35, 英語Messages Nurses Understand When Communicating with Mechanically Ventilated Patients in Critical Care: A Video-Based Descriptive Observational Study[査読有り]研究論文（学術雑誌）
- Scientific Research Publishing, Inc., 2022年12月, Health, 14(12) (12), 1244 - 1266, 英語[査読有り]研究論文（学術雑誌）
- Background. Mechanically ventilated critically ill patients need the opportunity to communicate their physical and psychosocial concerns to nurses. However, these patients face the unique problem of lacking even the opportunity to communicate. Aims. The study aimed to describe the characteristics of communication opportunities for critically ill mechanically ventilated patients. Methods. The study was designed as a video-based descriptive observational study. Participants included seven mechanically ventilated critically ill patients at the intensive care unit, coronary care unit, or high care unit who were conscious and seven registered nurses (seven pairs). Videos were recorded continuously from 8 am to 4 pm, and the footage was then descriptively analyzed. Data collection took place between July 2019 and June 2020. Results. The total recording time was 668.0 minutes. Of these 668.0 minutes, nurses stayed in the Conversation Area of the Patient for 279.6 minutes, and of these 279.6 minutes, two-way face-to-face communication between nurse and patient occurred for 78.0 minutes. Of these 78.0 minutes, communications were started by nurses for 47.2 minutes (174 scenes) and by patients for 24.2 minutes (36 scenes). The patient-started two-way communication scenes included 37 instances of Patient-Intentional-Action that triggered the start of communication. Actions using the upper limbs were observed in 20 instances and represented the most frequently used body part. The head/face, lower limbs, or trunk were also used in some of the actions. Gestures were the most commonly used action type (14 instances). Other types included lip movement, grimace, leg flex/extension, and cough. Conclusions. We found that nurses tended to start communication more frequently than patients did and that patients demonstrated Patient-Intentional-Action with a variety of actions using various body parts. Communication opportunities for patients were created when nurses took the initiative to start communication or when they noticed and responded to the Patient-Intentional-Action. Our findings demonstrate that nurses need to recognize and always respond to Patient-Intentional-Action and to take the initiative in communicating rather than waiting for the patient to do so.Hindawi Limited, 2022年07月, Nursing Research and Practice, 2022, 1 - 11, 英語[査読有り]研究論文（学術雑誌）
- (一社)ITヘルスケア学会, 2021年08月, Japanese Journal of Applied IT Healthcare, 16(1) (1), 13 - 20, 英語[査読有り]研究論文（学術雑誌）
- Aim Increased crossing of finger nailfold capillaries could be a novel visual marker of early microvascular damage among type 2 diabetes mellitus patients. Although abdominal obesity is an important driver of early microvascular damage, its association with an increase in the percentage of crossing capillaries remains uncertain. We investigated the association between abdominal obesity and an increase in the percentage of crossing capillaries in the finger nailfold in patients with type 2 diabetes mellitus. Methods This cross-sectional study enrolled 123 type 2 diabetes mellitus patients (age 40-75 years) who visited the outpatient diabetic clinic at Osaka University Hospital between May and October 2019. Abdominal obesity was defined as a waist circumference >= 90 cm in women and >= 85 cm in men. Capillary morphology was assessed by nailfold capillaroscopy based on the simple capillaroscopic definitions of the European League Against Rheumatism Study Group. The association between abdominal obesity and a high percentage of crossing capillaries in the finger nailfold (defined as the highest tertile of crossing capillaries) was analyzed using multivariable logistic regression. Results After adjusting for age, sex, smoking status, regular exercise, duration of diabetes, glycated hemoglobin, hypertension, and dyslipidemia, abdominal obesity was significantly associated with a high percentage of crossing capillaries (multivariable-adjusted odds ratios [95% confidence interval] = 2.70 [1.05-6.90], p = 0.038). Conclusions Abdominal obesity may play an important role in the increase in the percentage of crossing capillaries in the finger nailfold in patients with type 2 diabetes mellitus.Springer Science and Business Media LLC, 2021年07月, Diabetology International, 12(3) (3), 260 - 267, 英語[査読有り]研究論文（学術雑誌）
- Aims/Introduction Crossing capillaries in the finger nailfold might potentially be a novel diabetic retinopathy (DR) biomarker that could be assessed non-invasively in the clinical setting. However, the association between crossing capillaries and DR is controversial. This study aimed to investigate the association between the percentage of crossing capillaries in the finger nailfold and DR in patients with type 2 diabetes mellitus.Materials and Methods This cross-sectional study enrolled 108 type 2 diabetes mellitus patients (aged 40-75 years) who visited the outpatient diabetic clinic at Osaka University Hospital, Osaka, Japan, between May and October 2019. Capillary morphology was assessed using nailfold capillaroscopy based on the simple capillaroscopic definitions of the European League Against Rheumatism Study Group. Details of DR and other laboratory data were obtained from medical records. The association between the tertile of the percentage of the crossing capillary and DR was analyzed using multivariable logistic regression.Results After adjusting for age, sex, diabetes duration, glycated hemoglobin, systolic blood pressure, body mass index, and use of renin-angiotensin system inhibitor and antihyperlipidemic medication, the percentage of crossing capillaries was significantly associated with DR (multivariable-adjusted odds ratios for increasing tertiles of the percentage of crossing capillary: 1 [reference], 2.05 [95% confidence interval 0.53-7.94], and 4.33 [95% confidence interval 1.16-16.21]; P-trend = 0.028).Conclusions A higher percentage of crossing capillaries in the nailfold was associated with a higher risk of DR, independent of traditional risk and inhibiting factors, in patients with type 2 diabetes mellitus.Wiley, 2021年06月, Journal of Diabetes Investigation, 12(6) (6), 1007 - 1014, 英語[査読有り]研究論文（学術雑誌）
- Purpose This study compared age differences in risk factors for falls requiring treatment in psychiatric patients. Design and Methods An incident database was used to compare fall incidents in patients aged less than 65 years and those aged greater than or equal to 65 years. Findings Approximately 30% of fallers were less than 65 years. Mental status and medication were the main risk factors. Decreased activities of daily living were associated with the most falls in patients greater than or equal to 65 years. Practice Implications Fall risk differed between the two age groups. Medication may play a major role in falls among patients less than 65 years.Wiley, 2021年01月, Perspectives in Psychiatric Care, 57(1) (1), 311 - 317, 英語[査読有り]研究論文（学術雑誌）
- OBJECTIVES: The objective of this study was to evaluate the validity of Eurolung risk models in a Japanese population and assess their utility as predictive indicators for the prognosis. METHODS: Between 2007 and 2014, 612 anatomic lung resections were performed among 694 lung cancer patients in our institution. We analysed the cardiopulmonary morbidity and mortality and compared them with the predicted results. We also investigated the association between the Eurolung aggregate risk scores and the long-term outcomes using the Kaplan-Meier method and a multivariable analysis. RESULTS: The percentage of cardiopulmonary complications was lower than that predicted by Eurolung 1 (22.4% vs 24.6%). The mortality rate was significantly lower than predicted by Eurolung 2 (0.7% vs 3.0%). The morbidity rate was stratified by Aggregate Eurolung 1. The stratification of the mortality rate by the Eurolung 2 aggregate score was also in line with the increase in score, although the observed number of deaths was quite small (4 cases). The 5-year overall survival was clearly separated according to the stratified Aggregate Eurolung 1 and 2 (P < 0.01 and P < 0.01, respectively). Besides pathological stage, both the Aggregate Eurolung 1 (score 0-7 vs 8-20) and 2 (score 0-8 vs 9-19) scores were shown to be independently associated with overall survival on multivariable. CONCLUSIONS: Eurolung risk models cannot be directly applied to the patients in our institution. However, Eurolung aggregate risk scores were helpful not only for stratifying morbidity and mortality after anatomic lung resection but also for predicting the long-term outcomes.2019年11月, Interactive cardiovascular and thoracic surgery, 29(5) (5), 722 - 728, 英語, 国際誌[査読有り]研究論文（学術雑誌）
- Falls are an important health issue for older people, as they lead to increased morbidity and mortality and reduced physical function, activities of daily living, and quality of life. Skin sensation is an indicator of the ability to maintain balance, which is a factor in fall risk. We investigated the validity of a computer-controlled plantar-foot sensation-testing instrument (PFS tester) that measures skin sensation. We examined the within-subject reproducibility of skin sensation thresholds and their relationship to balance in older participants. Within-subject skin sensation threshold reproducibility was examined using intraclass correlation coefficients. The skin sensation thresholds showed moderate within-subject reproducibility. The associations between skin sensation thresholds and balance were examined using multiple regression analysis. We found a significant relationship between skin sensation thresholds and balance. The results indicate that the PFS tester is clinically applicable and a reliable indicator of balance ability.IOS Press, 2024年07月24日, Studies in Health Technology and Informatics, 315, 740 - 741, 英語記事・総説・解説・論説等（国際会議プロシーディングズ）
- 2024年06月, 大阪ガスグループ福祉財団 調査・研究報告集, 37, 99 - 105, 日本語感覚評価装置を用いた手掌の皮膚感覚と転倒の関連の検討
- 2023年03月, Bulletin of Health Sciences Kobe, 38, 45 - 56, 英語Effect of Wiping Pressure on Body Hygiene of Bed Bath with a Wet Washcloth
- フレグランスジャーナル社, 2023年02月, AROMA RESEARCH, 24(1) (1), 7 - 13, 日本語マイクロメートルの違いが拓く皮膚感覚と匂いの世界：高精度の足底感覚計の開発と匂いが皮膚感覚に及ぼす影響の検出[査読有り]記事・総説・解説・論説等（学術雑誌）
- IEEE, 2020年03月, 2020 IEEE 2nd Global Conference on Life Sciences and Technologies (LifeTech), 英語[査読有り]記事・総説・解説・論説等（国際会議プロシーディングズ）
- 2015年03月, 大阪大学看護学雑誌, 21(211) (211), 37 - 39, 日本語国際交流：台北医科大学夏季研修でのボランティア体験速報，短報，研究ノート等（大学，研究機関紀要）
- 第83回日本公衆衛生学会総会, 2024年10月, 日本語高齢者における足底感度と転倒経験、筋力・筋肉量等指標との関係～パイロットスタディ～
- 第83回日本公衆衛生学会総会, 2024年10月, 日本語高齢者と若年者との認知反応時間の比較～パイロットスタディ～口頭発表（一般）
- The 27TH East Asian Forum of Nursing Scholars Conference, 2024年03月, 英語Nurses’ and nursing students’ cue recognition and utilization in clinical reasoning and judgment: A scoping review
- The 27TH East Asian Forum of Nursing Scholars Conference, 2024年03月, 英語What Skills Are Required for Handoffs between Nurses? A Scoping Reviewポスター発表
- 第11回看護理工学会学術集会, 2023年06月, 日本語医療現場において看護職が実施する製品等のモニター評価に関わる業務の実態・求められるスキルに関するインタビュー調査ポスター発表
- 第93回日本衛生学会学術総会, 2023年03月, 日本語2型糖尿病患者における眼科未受診者の特性 糖尿病網膜症の有無別の検討ポスター発表
- The 16th International Conference on Advanced Technologies & Treates for Diabetes, 2023年02月, 英語ASSOCIATION BETWEEN MAXIMUM LIFETIME BODY MASS INDEX, BODY MASS INDEX AT SURVEY, AND CROSSING CAPILLARIES IN THE FINGER NAILFOLD IN TYPE 2 DIABETES MELLITUSポスター発表
- 第10回看護理工学会学術集会, 2022年10月, 日本語同一被験者における手掌及び足底の皮膚感覚閾値の再現性に関する研究ポスター発表
- 第10回看護理工学会学術集会, 2022年10月, 日本語ナースコール発報数に影響を与える患者要因の検証 -年齢に着目して-
- 第10回看護理工学会学術集会, 2022年10月, 日本語ナースコール発報数に影響を与える患者要因の検証 -認知・認識力に着目して-口頭発表（一般）
- 第10回看護理工学会学術集会, 2022年10月, 日本語ナースコール発報数に影響を与える患者要因の検証 -重症度に着目して-口頭発表（一般）
- The 25TH East Asian Forum of Nursing Scholars Conference, 2022年04月, 英語Feasibility of screening tests on the palm using a computerized quantitative skin sensation evaluation device
- The 49th Annual Meeting of the Japanese Society of Intensive Care Medicine, 2022年03月, 英語Characteristics of scenes in which mechanically ventilated critically ill patients actively communicate: Video-based descriptive observational study口頭発表（一般）
- The 11th International Congress of Diabetes and Metabolism and The 13th AASD Scientific Meeting, 2021年10月, 英語Association of crossing capillaries in the finger nailfold with diabetic nephropathy in type 2 diabetes mellitusポスター発表
- 第48回⽇本集中治療医学会学術集会, 2021年02月, 日本語意識下⼈⼯呼吸器装着患者の症状マネジメントのためのコミュニケーション⽅法シンポジウム・ワークショップパネル（指名）
- 第5回日本糖尿病・生活習慣病ヒューマンデータ学会, 2020年12月, 日本語2型糖尿病患者における腹部肥満と爪郭部毛細血管の捻転との関連口頭発表（一般）
- 第51回日本看護学会学術集会, 2020年11月, 日本語看護現場へのAIの活用 ビッグデータを看護にどう活用するか口頭発表（招待・特別）
- 第8回看護理工学会学術集会, 2020年10月, 日本語アンプルカット動作における指先軌道についてポスター発表
- 第8回看護理工学会学術集会, 2020年10月, 日本語ナースコール発報数が多い患者が病棟全体の発報規則に及ぼす影響の検証ポスター発表
- 第57回日本糖尿病学会近畿地方会, 2020年10月, 日本語2型糖尿病患者における爪郭部毛細血管の捻転と糖尿病網膜症との関連ポスター発表
- The 6th International Nursing Research Conference of World Academy of Nursing Science (The 6th WANS), 2020年02月, 英語Differences in the risk of falls between individuals <65 years-old and ≥65 years-old at a psychiatric hospital in Japanポスター発表
- The 23rd East Asian Forum of Nursing Scholars (The 23rd EAFONS), 2020年01月, 英語Development of speech-to-text system for real-time nursing record in operating room : A preliminary studyポスター発表
- 第11回多感覚研究会, 2019年12月, 日本語若年女性の冷え性と足底感覚の検討ポスター発表
- 日本行動計量学会第47回大会, 2019年09月, 日本語手術室看護記録の音声入力支援に関する基礎的検討 2 個別マイクと定点マイクの雑音ののりかたの比較口頭発表（一般）
- 日本行動計量学会第47回大会, 2019年09月, 日本語手術室看護記録の音声入力支援に関する基礎的検討 1 周術期看護分野での音声入力変換のための辞書つくり口頭発表（一般）
- THE 10th INTERNATIONAL ASSOCIATION OF GERONTOLOGY AND GERIATRICS (IAGG) - ASIA/OCEANIA 2015 CONGRESS (IAGG ASIA/OCEANIA 2015), 2015年10月, 英語The pattern of fall incidents at a psychiatric hospital in Japan: a quantitative analysis of incident reports, 2001-2012ポスター発表
- The 4th International Nursing Research Conference of World Academy of Nursing Science (The 4th WANS), 2015年10月, 英語Analysis of incident reports of absconding behavior at a Japanese psychiatric hospital over a 12-year periodポスター発表
- The 4th International Nursing Research Conference of World Academy of Nursing Science (The 4th WANS), 2015年10月, 英語Long-term trend of medication errors in a Japanese psychiatric hospitalポスター発表
- 第2回看護理工学学会学術集会, 2014年10月, 日本語蒸しタオル清拭における清拭圧の違いが清拭後皮膚に残る汚れに及ぼす影響ポスター発表
- 一般社団法人日本認知症ケア学会2014年度関西地域大会, 2014年09月, 日本語若年性認知症の日常的ケア支援データベースシステムの開発口頭発表（一般）
- 一般社団法人日本認知症ケア学会2014年度関西地域大会, 2014年09月, 日本語若年性認知症者の行動心理学的兆候に対して家族介護者が行う対処行動 -グループインタビューの質的分析結果-口頭発表（一般）
- 一般社団法人日本認知症ケア学会2014年度関西地域大会, 2014年09月, 日本語若年認知症患者に対する家族介護者の日常的なケアにおける基本的な関わり-グループインタビューの質的研究-口頭発表（一般）
- 一般社団法人日本公衆衛生学会2024年05月 - 現在
- 一般社団法人日本老年看護学会2022年04月 - 現在
- 一般社団法人日本生活支援工学会2022年04月 - 現在
- 看護理工学会2022年04月 - 現在
- 一般社団法人 ITヘルスケア学会2020年10月 - 現在
- 公益財団法人サッポロ生物科学振興財団, 2025年度 研究助成, 2025年04月 - 2026年03月, 研究代表者発酵食品の匂いが嗜好と食行動に与える影響の日本とモンゴルの国際比較：脳活動と主観的体験の両面からの分析
- 一般財団法人ノーリツぬくもり財団, 研究助成事業, 2024年10月 - 2025年09月, 研究代表者高齢者の皮膚感覚機能の個別性を考慮した転倒リスク評価指標の検討
- 日本学術振興会, 科学研究費助成事業 若手研究, 若手研究, 神戸大学, 2022年04月 - 2025年03月, 研究代表者手掌の皮膚感覚に着目した糖尿病神経障害、高齢者の転倒リスク評価指標の検討
- 大阪ガスグループ福祉財団, 高齢者の福祉および健康づくりに関する調査・研究助成, 大阪大学, 2021年03月 - 2022年04月, 研究代表者感覚評価装置を用いた手掌の皮膚感覚と転倒の関連の検討
- 大阪大学国際医工情報センター, MDD Grant2020, 大阪大学, 2020年11月 - 2021年03月, 研究代表者せん断刺激を加えることで皮膚感覚を数値化できる感覚評価装置のアルゴリズム開発
■ その他