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検索詳細木内 邦彦大学院医学研究科 医療創成工学専攻教授
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■ 学位■ 研究ニュース
■ 研究キーワード
■ 研究分野
■ 委員歴
研究活動情報
■ 論文- 2023年07月, Journal of Cardiovascular Electrophysiology研究論文(学術雑誌)
- (一社)日本循環器学会, 2023年03月, 日本循環器学会学術集会抄録集, 87回, CP20 - 5, 日本語植込み型心臓電気デバイス(CIED)植込み患者の植込み6ヵ月後の活動・睡眠の実態と関連要因
- 2023年03月, Clinical Case Reports研究論文(学術雑誌)
- 2023年03月, Journal of Cardiovascular Electrophysiology研究論文(学術雑誌)
- (一社)日本循環器学会, 2023年03月, 日本循環器学会学術集会抄録集, 87回, CP20 - 5, 日本語植込み型心臓電気デバイス(CIED)植込み患者の植込み6ヵ月後の活動・睡眠の実態と関連要因
- AIMS: Accessory pathway (AP) ablation is a standard procedure for the treatment of Wolff-Parkinson-White syndrome (WPW). Twelve-lead electrocardiogram (ECG)-based delta wave analysis is essential for predicting ablation sites. Previous algorithms have shown to be complex, time-consuming, and unprecise. We aimed to retrospectively develop and prospectively validate a new, simple ECG-based algorithm considering the patients' heart axis allowing for exact localization of APs in patients undergoing ablation for WPW. METHODS AND RESULTS: Our multicentre study included 211 patients undergoing ablation of a single manifest AP due to WPW between 2013 and 2021. The algorithm was developed retrospectively and validated prospectively by comparing its efficacy to two established ones (Pambrun and Arruda). All patients (32 ± 19 years old, 47% female) underwent successful pathway ablation. Prediction of AP-localization was correct in 197 patients (93%) (sensitivity 92%, specificity 99%, PPV 96%, and NPV 99%). Our algorithm was particularly useful in correctly localizing antero-septal/-lateral (sensitivity and specificity 100%) and posteroseptal (sensitivity 98%, specificity 92%) AP in proximity to the tricuspid valve. The accuracy of EASY-WPW was superior compared to the Pambrun (93% vs. 84%, P = 0.003*) and the Arruda algorithm (94% vs. 75%, P < 0.001*). A subgroup analysis of children (n = 58, 12 ± 4 years old, 55% female) revealed superiority to the Arruda algorithm (P < 0.001*). The reproducibility of our algorithm was excellent (ϰ>0.8; P < 0.001*). CONCLUSION: The novel EASY-WPW algorithm provides reliable and accurate pre-interventional ablation site determination in WPW patients. Only two steps are necessary to locate left-sided AP, and three steps to determine right-sided AP.2023年02月, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 25(2) (2), 600 - 609, 英語, 国際誌研究論文(学術雑誌)
- 2023年, Circulation Journal, 87(1) (1)研究論文(学術雑誌)
- 2023年, Indian Pacing and Electrophysiology Journal, 23(4) (4)研究論文(学術雑誌)
- 2023年, Journal of Arrhythmia, 39(1) (1)研究論文(学術雑誌)
- 2023年, JACC: Clinical Electrophysiology, 9(9) (9)研究論文(学術雑誌)
- 2022年12月, Journal of Arrhythmia研究論文(学術雑誌)
- BACKGROUND: Several algorithms have been proposed for differentiating the right and left outflow tracts (RVOT/LVOT) arrhythmia origins from 12-lead electrocardiograms (ECGs); however, the procedure is complicated. A deep learning (DL) model, a form of artificial intelligence, can directly use ECGs and depict the importance of the leads and waveforms. This study aimed to create a visualized DL model that could classify arrhythmia origins more accurately.Methods and Results: This study enrolled 80 patients who underwent catheter ablation. A convolutional neural network-based model that could classify arrhythmia origins with 12-lead ECGs and visualize the leads that contributed to the diagnosis using a gradient-weighted class activation mapping method was developed. The average prediction results of the origins by the DL model were 89.4% (88.2-90.6) for accuracy and 95.2% (94.3-96.2) for recall, which were significantly better than when a conventional algorithm is used. The ratio of the contribution to the prediction differed between RVOT and LVOT origins. Although leads V1 to V3 and the limb leads had a focused balance in the LVOT group, the contribution ratio of leads aVR, aVL, and aVF was higher in the RVOT group. CONCLUSIONS: This study diagnosed the arrhythmia origins more accurately than the conventional algorithm, and clarified which part of the 12-lead waveforms contributed to the diagnosis. The visualized DL model was convincing and may play a role in understanding the pathogenesis of arrhythmias.2022年07月, Circulation journal : official journal of the Japanese Circulation Society, 86(8) (8), 1273 - 1280, 英語, 国内誌研究論文(学術雑誌)
- Wiley, 2022年06月, Journal of Arrhythmia研究論文(学術雑誌)
- Background: Some of atrial fibrillation (AF) drivers are found in normal/mild late-gadolinium enhancement (LGE) areas, as well as moderate ones. The atrial wall thickness (AWT) has been reported to be important as a possible AF substrate. However, the AWT and degree of LGEs as an AF substrate has not been fully validated in humans. Objective: The purpose of this study was to evaluate the impact of the AWT in normal/mild LGE areas on AF drivers. Methods: A total of 287 segments in 15 persistent AF patients were assessed. AF drivers were defined as non-passively activated areas (NPAs), where rotational activation was frequently observed, and were detected by the novel real-time phase mapping (ExTRa Mapping), mild LGE areas were defined as areas with a volume ratio of the enhancement voxel of 0% to <10%. The AWT was defined as the minimum distance from the manually determined endocardium to the epicardial border on the LGE-MRI. Results: NPAs were found in 20 (18.0%) of 131 normal/mild LGE areas where AWT was significantly thicker than that in the passively activated areas (PAs) (2.5 ± 0.3 vs. 2.2 ± 0.3 mm, p < .001). However, NPAs were found in 41 (26.3%) of 156 moderate LGE areas where AWT was thinner than that of PAs (2.1 ± 0.2 mm vs. 2.23 ± 0.3 mm, p = .02). An ROC curve analysis yielded an optimal cutoff value of 2.2 mm for predicting the presence of an NPA in normal/mild LGE areas. Conclusion: The location of AF drivers in normal/mild LGE areas might be more accurately identified by evaluating AWT.2022年04月, Journal of arrhythmia, 38(2) (2), 221 - 231, 英語, 国内誌研究論文(学術雑誌)
- 2022年, JACC: Case Reports, 4(23) (23)研究論文(学術雑誌)
- 2022年, Journal of Cardiovascular Electrophysiology, 33(8) (8)研究論文(学術雑誌)
- 2022年, American Journal of Cardiology, 181研究論文(学術雑誌)
- Indian Pacing and Electrophysiology Group, 2021年09月, Indian Pacing and Electrophysiology Journal, 21(5) (5), 308 - 312, 英語研究論文(学術雑誌)
- BACKGROUND: A substantial number of patients with shock devices (implantable cardioverter defibrillators [ICDs] or ICDs with resynchronization [CRTDs]) experience psychological distress. OBJECTIVE: We investigated the device nurse telephone intervention's effect on improving the patient's adaptation to shock devices, quality of life (QOL), and anxiety in the remote monitoring era. METHODS: The patient's adaptation to the device, health-related QOL, and anxiety were investigated by the modified Implanted Devices Adjustment-Japan score (IDAS), Short Form-36, and State-Trait Anxiety Inventory (STAI) before and 1-year after the device nurse telephone intervention, performed every 3 months. A total of 95 patients (median age 69 years and 25 females) participated. Sixty patients had ICDs and 35 CRTDs. Structural heart disease was observed in 72 patients, and idiopathic ventricular arrhythmias in the others. The mean left ventricular ejection fraction was 46% ± 15%. The median duration since the device implantation was 5.2 years. RESULTS: The total IDAS score significantly improved from 28.42 ± 7.11 at baseline to 26.77 ± 7.68 (p = 0.0076) at 1 year. Both the state and trait anxiety significantly improved (from 38.9 ± 9.6 to 35.3 ± 9.0 [<0.0001] and 38.8 ± 10.3 to 36.2±9.8 [p = 0.0044], respectively). The prevalence of patients with a state and trait anxiety of more than 40 decreased from 44 (46%) and 38 (40%) patients before the study to 27 (28 %) and 32 (34 %) at 1 year. The SF-36 mental component summary score significantly increased (50.8 ± 8.3 at baseline to 53.1 ± 7.7 at 1 year, p = 0.0031). CONCLUSIONS: The device nurse intervention facilitated the patient's adaptation to the shock device, increased the health-related QOL, and reduced the patient's anxiety.2021年08月, Pacing and clinical electrophysiology : PACE, 英語, 国際誌研究論文(学術雑誌)
- Atrial tachycardia (AT) in the right atrium often occurs following open-heart surgery. Catheter ablation for these AT is challenging and can lead to unintended conduction block. We performed late-gadolinium enhancement magnetic resonance imaging (LGE-MRI) prior to catheter ablation and predicted wavefront propagation during SR as well as the slow conduction zone during tachycardia. LGE-MRI may assist predicting the conduction disturbance and reducing the risk of unexpected sinus exit block.2021年06月, Clinical case reports, 9(6) (6), e04198, 英語, 国際誌
- A 61-year-old female with 50 000 ventricular premature contractions and a reduced left ventricular ejection fraction of 35% was referred to our center. Although the origin was considered to originate from the junction between the left and right coronary cusp, a single radiofrequency application above the aortic sinus cusp could eliminate it. LGE-MRI was able to reveal the exact location of the single RF lesion.2021年06月, Clinical case reports, 9(6) (6), e04169, 英語, 国際誌
- Background: Demand is growing for remote electrocardiogram (ECG) monitoring systems in the COVID-19 era in Japan. This study describes initial experiences with a small wireless ECG monitoring device and the utility of delivery via the postal service for outpatient care in Japan. Methods and Results: Long-term ECG monitoring following postal delivery of the small ECG device was evaluated in 25 patients. The patients had no difficulties with either the postal delivery or self-fitting and wearing the devices. A median of 57 h monitoring per patient was performed. Arrhythmic events were detected in 8 patients. Most patients were satisfied with both the ECG devices and postal delivery. Conclusions: Postal delivery of ECG devices could be used in clinical practice to achieve less or no in-person contact during the COVID-19 era.2021年04月, Circulation reports, 3(5) (5), 294 - 299, 英語, 国内誌研究論文(学術雑誌)
- Cardiac accessory pathways (APs) in Wolff-Parkinson-White (WPW) syndrome are conventionally diagnosed with decision tree algorithms; however, there are problems with clinical usage. We assessed the efficacy of the artificial intelligence model using electrocardiography (ECG) and chest X-rays to identify the location of APs. We retrospectively used ECG and chest X-rays to analyse 206 patients with WPW syndrome. Each AP location was defined by an electrophysiological study and divided into four classifications. We developed a deep learning model to classify AP locations and compared the accuracy with that of conventional algorithms. Moreover, 1519 chest X-ray samples from other datasets were used for prior learning, and the combined chest X-ray image and ECG data were put into the previous model to evaluate whether the accuracy improved. The convolutional neural network (CNN) model using ECG data was significantly more accurate than the conventional tree algorithm. In the multimodal model, which implemented input from the combined ECG and chest X-ray data, the accuracy was significantly improved. Deep learning with a combination of ECG and chest X-ray data could effectively identify the AP location, which may be a novel deep learning model for a multimodal model.2021年04月, Scientific reports, 11(1) (1), 8045 - 8045, 英語, 国際誌研究論文(学術雑誌)
- Background Medium-dose (25 gray) x-ray radiation therapy has recently been performed on patients with refractory ventricular tachyarrhythmias. Unlike x-ray, carbon ion and proton beam radiation can deliver most of their energy to the target tissues. This study investigated the electrophysiological and pathological changes caused by medium-dose carbon ion and proton beam radiation in the left ventricle (LV). Methods and Results External beam radiation in the whole LV was performed in 32 rabbits. A total of 9 rabbits were not irradiated (control). At the 3-month or 6-month follow-up, the animals underwent an open-chest electrophysiological study and were euthanized for histological analyses. No acute death occurred. Significant LV dysfunction was not seen. The surface ECG revealed a significant reduction in the P and QRS wave voltages in the radiation groups. The electrophysiological study showed that the local conduction times in each LV site were significantly longer and that the local LV bipolar voltages were significantly lower in the radiation groups than in the control rabbits. Histologically, apoptosis, fibrotic changes, and a decrease in the expression of the connexin 43 protein were seen in the LV myocardium. These changes were obvious at 3 months, and the effects were sustained 6 months after radiation. No histological changes were seen in the coronary artery and esophagus, but partial radiation pneumonitis was observed. Conclusions Medium-dose carbon ion and proton beam radiation in the whole LV resulted in a significant electrophysiological disturbance and pathological changes in the myocardium. Radiation of the arrhythmogenic substrate would modify the electrical status and potentially induce the antiarrhythmic effect.2021年04月, Journal of the American Heart Association, 10(7) (7), e019687, 英語, 国際誌研究論文(学術雑誌)
- (一社)日本循環器学会, 2021年03月, 日本循環器学会学術集会抄録集, 85回, OE022 - 7, 英語The Lesion Continuity after Pulmonary Vein Isolation with LSI of 5 vs 6: Late-gadolinium Enhancement Magnetic Resonance Imaging(LGE-MRI) Analysis(和訳中)
- (一社)日本循環器学会, 2021年03月, 日本循環器学会学術集会抄録集, 85回, OE032 - 2, 英語The Relationship between AF Rotor Detected by ExTRa Mapping and Tissue Property Assessed by LGE-MRI in Persistent Atrial Fibrillation Patients(和訳中)
- (一社)日本循環器学会, 2021年03月, 日本循環器学会学術集会抄録集, 85回, OE045 - 1, 英語Acute Response and Rhythm Outcome of the Patchy Late-gadolinium Enhancement Sites Ablation in Patients with Atrial Fibrillation: LGE-MRI Analysis(和訳中)
- (一社)日本循環器学会, 2021年03月, 日本循環器学会学術集会抄録集, 85回, OE075 - 1, 英語The Importance of the HCM Phenotype in the Management of Ventricular Arrhythmias and Implanted Cardioverter Defibrillators(和訳中)
- (一社)日本循環器学会, 2021年03月, 日本循環器学会学術集会抄録集, 85回, OE075 - 4, 英語Clinical Outcomes Following Upgrade to Cardiac Resynchronization Therapy in Patients with Cardiac Sarcoidosis(和訳中)
- (一社)日本循環器学会, 2021年03月, 日本循環器学会学術集会抄録集, 85回, OE135 - 3, 英語Net Clinical Benefit of Oral Anticoagulation Therapy in Elderly Patients with Atrial Fibrillation: The Hyogo AF Network(HAF-NET) Registry(和訳中)
- BACKGROUND: Coronary artery spasms (CASs), which can cause angina attacks and sudden death, have been recently reported during catheter ablation. The aim of the present study was to report the incidence, characteristics, and prognosis of CASs related to atrial fibrillation (AF) ablation procedures.Methods and Results:The AF ablation records of 22,232 patients treated in 15 Japanese hospitals were reviewed. CASs associated with AF ablation occurred in 42 of 22,232 patients (0.19%). CASs occurred during ablation energy applications in 21 patients (50%). CASs also occurred before ablation in 9 patients (21%) and after ablation in 12 patients (29%). The initial change in the electrocardiogram was ST-segment elevation in the inferior leads in 33 patients (79%). Emergency coronary angiography revealed coronary artery stenosis and occlusions, which were relieved by nitrate administration. No air bubbles were observed. A comparison of the incidence of CASs during pulmonary vein isolation between the different ablation energy sources revealed a significantly higher incidence with cryoballoon ablation (11/3,288; 0.34%) than with radiofrequency catheter, hot balloon, or laser balloon ablation (8/18,596 [0.04%], 0/237 [0%], and 0/111 [0%], respectively; P<0.001). CASs most often occurred during ablation of the left superior pulmonary vein. All patients recovered without sequelae. CONCLUSIONS: CASs related to AF ablation are rare, but should be considered as a dangerous complication that can occur anytime during the periprocedural period.Japanese Circulation Society, 2021年02月, Circulation Journal, 85(3) (3), 264 - 271, 英語, 国内誌[査読有り]研究論文(学術雑誌)
- BACKGROUND: A computational model demonstrated that atrial fibrillation (AF) rotors could be distributed in patchy late-gadolinium enhancement (LGE) areas and play an important role in AF drivers. However, this was not validated in humans. OBJECTIVE: The purpose of this study was to evaluate the LGE properties of AF rotors in patients with persistent AF. METHODS: A total of 287 segments in 15 patients with persistent AF (long-standing persistent AF in 9 patients) that underwent AF ablation were assessed. Non-passively activated areas (NPAs), where rotational activation (AF rotor) was frequently observed, were detected by the novel real-time phase mapping (ExTRa Mapping). The properties of the LGE areas were assessed using the LGE heterogeneity and the density which was evaluated by the entropy (LGE-entropy) and the volume ratio of the enhancement voxel (LGE-volume ratio), respectively. RESULTS: NPAs were found in 61 (21%) of 287 segments and were mostly found around the pulmonary vein antrum. A receiver operating characteristic curve analysis yielded an optimal cutoff value of 5.7% and 10% for the LGE-entropy and LGE-volume ratio, respectively. The incidence of NPAs was significantly higher at segments with an LGE-entropy of >5.7 and LGE-volume ratio of >10% than at the other segments (38 [30%] of 126 vs. 23 [14%] of 161 segments; p = .001). No NPAs were found at segments with an LGE-volume ratio of >50% regardless of the LGE-entropy. Of five patients with AF recurrence, NPAs outside the PV antrum were not ablated in three patients and the remaining NPAs were ablated, but their LGE-entropy and LGE-volume ratio were low. CONCLUSION: AF rotors are mostly distributed in relatively weak and much more heterogenous LGE areas.Wiley, 2021年02月, Journal of Cardiovascular Electrophysiology, 32(4) (4), 1005 - 1013, 英語, 国際誌[査読有り]研究論文(学術雑誌)
- BACKGROUND: A computer simulation model has demonstrated that atrial fibrillation (AF) driver can be attached to heterogeneous fibrosis assessed by late gadolinium enhancement magnetic resonance imaging (LGE-MRI). However, it has not been well elucidated in patients with persistent AF. The aim of this study was to investigate whether radiofrequency (RF) applications in the fragmented LGE area (FLA) could terminate AF or convert it to atrial tachycardia (AT) and improve the rhythm outcome. METHODS: A total of 31 consecutive persistent AF patients with FLAs were enrolled (FLA ablation group, mean age: 69 ± 8 years, mean left atrial diameter: 42 ± 6 mm). A favorable response was defined as direct AF termination or AT conversion during RF applications at the FLA. The rhythm outcome was compared between the FLA ablation group and FLA burden-matched pulmonary vein isolation (PVI) group. RESULTS: Favorable responses were found in 15 (48%) of 31 patients in the FLA group (AF termination in seven, AT conversion in eight patients), but not in the PVI group. AF recurrence at 12 months follow-up was significantly less in the FLA ablation group than in the PVI group (4 [13%] vs. 12 [39%] of 31 patients, log-rank p = .023). In patients with a favorable response, AT recurred in 1 (7%) of 15 patients, but AF did not. CONCLUSIONS: FLA ablation could terminate AF or convert it to AT in half of the patients. No AF recurrence was documented in patients with a favorable response.Wiley, 2021年02月, Journal of Cardiovascular Electrophysiology, 32(4) (4), 1014 - 1023, 英語, 国際誌[査読有り]研究論文(学術雑誌)
- BACKGROUND: Inflammation, such as that associated with intermediate CD14++ CD16+ monocytes and atrial structural remodeling (SRM), may be important in the recurrence of atrial fibrillation (AF) after catheter ablation. However, the relationship between the intermediate CD14++ CD16+ monocytes, SRM, and AF recurrence is unclear. METHODS: Twenty-four patients with AF were enrolled. The proportion of intermediate monocytes (PIM) was assessed before ablation by flow cytometry. As a surrogate marker of SRM, the volume ratio (VR) of signal intensity greater than 1 standard deviation on late-gadolinium enhancement magnetic resonance imaging (LGE-MRI) was calculated. We investigated whether PIM correlated with SRM on LGE-MRI and determined the optimal cutoff value for predicting AF recurrence. RESULTS: Univariate analysis revealed positive correlations between PIM and BNP with SRM (PIM: r = .593, p = .002; BNP: r = .567, p = .004). Multivariable analysis revealed that PIM was independently associated with VR on LGE-MRI (β = .522; p = .033). The finding of an area under the receiver operating characteristic curve of 0.750 revealed that a VR ≥ 13.3% on LGE-MRI as the optimal cutoff value to predict AF recurrence with 80% sensitivity and 71% specificity, which was associated with PIM ≥ 10.0%. CONCLUSION: Intermediate monocytes were significantly positively correlated with SRM. PIM ≥ 10% was associated with a VR ≥ 13.3% on LGE-MRI, which predicted AF recurrence after catheter ablation.Wiley, 2021年02月, Journal of Cardiovascular Electrophysiology, 32(4) (4), 1035 - 1043, 英語, 国際誌[査読有り]研究論文(学術雑誌)
- (一社)日本遠隔医療学会, 2021年02月, 日本遠隔医療学会学術大会プログラム・抄録集, 24回, 59 - 59, 英語心房細動患者への小型ワイヤレスECGモニタリング装置の郵送サービスの有用性(The utility of using the postal delivery service to deliver small wireless ECG monitoring devices to patients with atrial fibrillation)
- BACKGROUND: Pulmonary vein isolation (PVI) lesions after cryoballoon ablation (CBA) are characterized as a wider and more continuous than that after conventional radiofrequency catheter ablation (RFCA) without the contact force (CF)-sensing technology. However, the impact on the lesion characteristics of ablation with a CF-sensing catheter has not been well discussed. We sought to assess the lesions using late-gadolinium enhancement magnetic resonance imaging (LGE-MRI) and to compare the differences between the two groups (CB group vs. RF group). METHODS: A total of 30 consecutive patients who underwent PVI were enrolled (CB group, 18; RF group, 12). The RF applications were delivered with a target lesion size index (LSI) of 5. The PVI lesions were assessed by LGE-MRI 3 months after the PVI. The region around the PV was divided into eight segments: roof, anterior-superior, anterior carina, anterior inferior, bottom, posterior inferior, posterior carina, and posterior superior segment. The lesion width and visual gap of each segment were compared between the two groups. The visual gaps were defined as no-enhancement site of >4 mm. RESULTS: The mean LSI was 4.7 ± 0.7. The lesion width was significantly wider but the visual gaps were more frequently documented at the bottom segment of right PV in the CBA group (lesion width: 8.1 ± 2.2 vs. 6.3 ± 2.2 mm; p = .032; visual gap at the bottom segment or right PV: 39% vs. 0%; p = .016). CONCLUSIONS: The PVI lesion was wider after CBA, while the visual gaps were fewer after RFCA with a CF-sensing catheter.Wiley, 2020年10月, Journal of Cardiovascular Electrophysiology, 31(10) (10), 2572 - 2581, 英語, 国際誌[査読有り]研究論文(学術雑誌)
- (一社)日本循環器学会, 2020年07月, 日本循環器学会学術集会抄録集, 84回, OE127 - 2, 英語非侵襲的な粒子線外部照射が動物心臓の電気生理学的、病理学的変化に及ぼす影響(Impact of Non-invasive External Particle Beam Radiation on the Electrophysiological and Pathological Changes in the Animal Heart)
- (一社)日本循環器学会, 2020年07月, 日本循環器学会学術集会抄録集, 84回, CP6 - 4, 日本語遠隔モニタリング診療を受けている心臓デバイス(ICD,CRT-D)植込み患者へのデバイスナースによる支援効果(第1報)
- (一社)日本循環器学会, 2020年07月, 日本循環器学会学術集会抄録集, 84回, OJ15 - 4, 英語心房細動患者における循環血中CD14++CD16+単球上のToll様受容体4のアップレギュレーションは低電位領域と相関している(Toll-like Receptor 4 Upregulation on Circulating CD14++CD16+monocytes Correlates with the Low-voltage Zones in Patients with Atrial Fibrillation)
- (一社)日本循環器学会, 2020年07月, 日本循環器学会学術集会抄録集, 84回, OE76 - 2, 英語ラジオ波焼灼術が心房細動患者におけるpatchy遅延造影部位に及ぼす影響 LGE-MRIによる解析(The Impact of the Radiofrequency Application on the Patchy Late-gadolinium Enhancement Sites in Patients with Atrial Fibrillation: LGE-MRI Analysis)
- (一社)日本循環器学会, 2020年07月, 日本循環器学会学術集会抄録集, 84回, OE104 - 1, 英語心房細動患者におけるLGE-MRIで描出された線維化領域とExTRa Mappingで記録された非受動的興奮領域との関連(The Relationship between Fibrotic Areas Assessed by LGE-MRI and Non-Passively Activated Areas Detected by ExTRa Mapping in Atrial Fibrillation Patients)
- (一社)日本循環器学会, 2020年07月, 日本循環器学会学術集会抄録集, 84回, OE127 - 2, 英語非侵襲的な粒子線外部照射が動物心臓の電気生理学的、病理学的変化に及ぼす影響(Impact of Non-invasive External Particle Beam Radiation on the Electrophysiological and Pathological Changes in the Animal Heart)
- (一社)日本循環器学会, 2020年07月, 日本循環器学会学術集会抄録集, 84回, PE55 - 4, 英語植込み型心臓電気デバイス感染の微生物学的特徴と抗生物質の選択(Microbiological Characteristics and Selection of Antibiotics for Cardiac Implantable Electronic Device Infection in Our Hospital)
- (一社)日本循環器学会, 2020年07月, 日本循環器学会学術集会抄録集, 84回, CP6 - 4, 日本語遠隔モニタリング診療を受けている心臓デバイス(ICD,CRT-D)植込み患者へのデバイスナースによる支援効果(第1報)
- (一社)日本循環器学会, 2020年07月, 日本循環器学会学術集会抄録集, 84回, OJ15 - 4, 英語Toll-like Receptor 4 Upregulation on Circulating CD14++CD16+monocytes Correlates with the Low-voltage Zones in Patients with Atrial Fibrillation(和訳中)
- Inflammation has been suggested to play a key role in the pathogenesis of atrial fibrillation (AF). Our hypothesis was that this inflammation, mediated by intermediate monocytes and toll-like receptor 4 (TLR4), causes the formation and expansion of low-voltage zones (LVZs). Prior to ablation, the monocyte subsets of 78 AF patients and TLR4 expression of 66 AF patients were analyzed via a flow cytometric analysis. Based on the CD14/CD16 expression, the monocytes were divided into three subsets: classical, intermediate, and non-classical. At the beginning of the ablation session, voltage mapping was performed. LVZs were defined as all bipolar electrogram amplitudes of < 0.5 mV. Correlations between the flow cytometric analysis results and presence of LVZs, as well as the total area of the LVZ, were examined. Patients with LVZs clearly had a higher proportion of intermediate monocytes (10.0 ± 3.6% vs. 7.2 ± 2.7%, p < 0.001) than those without LVZs. TLR4 was much more frequently expressed in the intermediate monocytes than other two monocyte subsets (p < 0.001). Moreover, the TLR4 expression level in intermediate monocytes correlated positively with the total area of the LVZs (r = 0.267, p = 0.030), especially in patients with paroxysmal AF (r = 0.365, p = 0.015). The intermediate monocytes and TLR4 expression positively correlated with LVZs in AF patients.2020年06月, Heart and vessels, 35(12) (12), 1717 - 1726, 英語, 国内誌[査読有り]研究論文(学術雑誌)
- INTRODUCTION: The ablation index (AI) and lesion size index (LSI) are novel markers for predicting the ablation lesion quality, however, collateral damage is still a concern. This study aimed to compare the lesion characteristics and tissue temperature profiles between 20 W (20 Ws) and 40 W (40 Ws) ablation settings under the same AI and LSI. METHODS: An ex vivo model consisting of swine myocardium (5-6 mm thickness) in a circulating, warmed saline bath was used. Twenty-one tissue temperature electrodes were used. Radiofrequency applications with different power settings were performed with a 10 to 12 g contact force until the AI and LSI reached 350 and 4.5, respectively. RESULTS: A total of 120 radiofrequency (RF) applications and 2520 tissue temperature profiles were analyzed. The speed of the tissue temperature rise with 40 Ws was significantly faster than that with 20 Ws. However, the maximum tissue temperature did not significantly differ between 20 and 40 Ws with the same AI (44.6°C ± 3.9°C vs 45.1°C ± 6.4°C, P = .73), and was significantly lower for 40 Ws with the same LSI (42.8°C ± 3.4°C vs 40.0°C ± 3.4°C, P = .003). For both the AI and LSI, the number of electrodes exhibiting high temperatures (≥39°C) was significantly larger and the duration of high tissue temperatures was significantly longer with 20 Ws. The thermal latency with 40 Ws was greater. CONCLUSIONS: Although the targeted AI and LSI were the same for both 20 and 40 Ws, the tissue temperature profiles differed greatly depending on the RF power setting. A high power setting based on the AI and LSI may reduce the collateral thermal damage.2020年01月, Journal of cardiovascular electrophysiology, 31(1) (1), 196 - 204, 英語, 国際誌[査読有り]研究論文(学術雑誌)
- A 41-year-old man with persistent atrial fibrillation (AF) underwent radiofrequency (RF) catheter ablation using an online real-time phase mapping system: ExTRa Mapping. Box isolation could not terminate AF. Subsequently, RF applications on nonpassively activated areas (NPAs), where rotational activations were frequently observed, at the posterior bottom of left atrium outside of box lesion could convert AF to common atrial flutter. Of interest, the NPA near the posterior bottom were located on the patchy fibrotic tissue area assessed by the late-gadolinium enhancement magnetic resonance imaging. This indicated the possibility of the critical AF rotor meandering through the fibrotic tissue area.2019年10月, Journal of arrhythmia, 35(5) (5), 733 - 736, 英語, 国内誌[査読有り]
- Background: Although anticoagulation therapy could reduce the risk of strokes in patients with atrial fibrillation (AF), large-scale investigations in the direct oral anticoagulant (DOAC) and AF catheter ablation (CA) era are lacking. Methods: This study was designed as a prospective, multicenter, observational study and a total of 2113 patients from 22 institutions were enrolled in the Hyogo area. Results: The mean age and CHADS2 score were 70.1 ± 10.8 years old and 1.5 ± 1.1, respectively. The follow-up period was 355 ± 43 days. CA was performed in 614 (29%) and DOACs were prescribed in 1118 (53%) patients. Ischemic strokes/systemic embolisms (SEs) and major bleeding occurred in 13 (0.6%) and 17 (0.8%) patients, respectively. New onset dementia, hospitalizations for cardiac events, and all-cause death occurred in eight (0.4%), 60 (2.8%), and 29 (1.4%) patients, respectively. A multivariate analysis demonstrated that persistent AF and the body weight (BW) were associated with ischemic strokes/SEs and major bleeding, respectively (persistent AF: hazard ratio, 9.57; 95%CI, 1.2-74.0; P = .03; BW: hazard ratio, 0.94; 95%CI, 0.90-0.99; P = .02). AFCA history was associated with the cardiac events (hazard ratio, 0.44; 95%CI, 0.20-0.99; P = .04). Age was associated with new onset dementia (hazard ratio, 1.1; 95%CI, 1.0-1.2; P = .03). Conclusions: In the DOAC and CA era, the incidence of ischemic strokes/SEs, major bleeding and cardiac events could be dramatically reduced in patients with AF. However, some unsolved issues of AF management still remain especially in elderly patients with persistent AF and a low BW.2019年10月, Journal of arrhythmia, 35(5) (5), 697 - 708, 英語, 国内誌[査読有り]研究論文(学術雑誌)
- 2019年10月, Journal of Cardiovascular Electrophysiology[査読有り]研究論文(学術雑誌)
- 2019年08月, Journal of cardiovascular electrophysiology, 30(8) (8), 1339 - 1340, 英語, 国際誌[査読有り]研究論文(学術雑誌)
- OBJECTIVES: This study aimed to confirm the precise course of a pericardiocentesis with the anterior approach using post-procedural computed tomography (CT). BACKGROUND: Percutaneous epicardial ventricular tachycardia (VT) ablation has been increasingly performed. Although the inferior approach has been the common method, the feasibility of the anterior approach has subsequently been reported. However, the precise course of the anterior approach has not been presented. METHODS: An epicardial ablation with the anterior approach was performed in 15 patients. At the end of the procedure, the epicardial sheath was exchanged for a drainage tube to monitor bleeding. Of those patients, in 9 procedures in 8 patients a CT scan was performed just after the procedure to confirm the course of the drainage tube and to rule out any complications. Epicardial ablation was indicated for a failed endocardial VT ablation in 7 patients and epicardial substrate modification in 1 patient with Brugada syndrome. RESULTS: Volume-rendered images reconstructed from CT demonstrated each course of the drainage tubes and their relation to the surrounding organs. These images revealed that the tube had a curved trace, and did not penetrate the diaphragm or pass through the abdominal cavity. No injury to the surrounding organs was detected in any of the cases. CONCLUSIONS: The precise course of the drainage tube placed along the trajectory of the anterior approach was able to be confirmed using post-procedural CT images. These images support the safety and feasibility of the anterior approach from the anatomic standpoint with a low incidence of abdominal viscera injury.2019年06月, JACC. Clinical electrophysiology, 5(6) (6), 730 - 741, 英語, 国際誌[査読有り]研究論文(学術雑誌)
- (一社)日本循環器学会, 2019年03月, 日本循環器学会学術集会抄録集, 83回, PL04 - 3, 英語LGE-MRI技術を用いた左心房線維性基質の画像化の実施可能性(Feasibility of Imaging Fibrotic Substrates in the Left Atrium Using LGE-MRI Technology)
- (一社)日本循環器学会, 2019年03月, 日本循環器学会学術集会抄録集, 83回, OE01 - 5, 英語Cryoballoonアブレーション治療および接触力センシング型カテーテルによるラジオ波焼灼療法におけるLGE-MRIにより評価した損傷特性(Lesion Characteristics Assessed by LGE-MRI between Cryo-balloon Ablation and Radiofrequency Ablation with Contact-force Sensing Catheter)
- (一社)日本循環器学会, 2019年03月, 日本循環器学会学術集会抄録集, 83回, OE36 - 4, 英語各種高周波出力設定が同じアブレーション条件下の組織温度プロファイルに及ぼす影響(Impact of Different Radiofrequency Power Settings on Tissue Temperature Profiles under the Same Ablation Index)
- (一社)日本循環器学会, 2019年03月, 日本循環器学会学術集会抄録集, 83回, CP27 - 3, 日本語遠隔モニタリング診療を受けている心臓デバイス(ICD、CRT-D)植込み患者の心理社会的特徴の検討
- (一社)日本循環器学会, 2019年03月, 日本循環器学会学術集会抄録集, 83回, PJ113 - 7, 英語心房細動患者における血中intermediate CD14++CD16+monocyteと心房電気的リモデリングとの相関関係(The Correlation between Circulating Intermediate CD14++CD16+Monocytes and Atrial Electrical Remodeling in Atrial Fibrillation Patients)[査読有り]
- A 69-year-old man, who had undergone surgery for mitral and tricuspid regurgitation with the Maze procedure for paroxysmal atrial fibrillation, was admitted with an episode of syncope due to sick sinus syndrome. Three days after implantation of a dual-chamber pacemaker (Accent MRI™, St. Jude Medical Inc.,), ventricular pacing on T-wave was recorded multiple times. St. Jude Medical Inc. pacemakers have a unique additional algorithm, called premature ventricular contraction response, related to preventing pacemaker-mediated tachycardia. This algorithm was determined to be a cause of ventricular pacing on T-wave. We report the limitations and potential adverse effects of such automated algorithms.2018年10月, Journal of arrhythmia, 34(5) (5), 572 - 575, 英語, 国内誌[査読有り]研究論文(学術雑誌)
- 2018年09月, HeartRhythm case reports, 4(9) (9), 389 - 392, 英語, 国際誌[査読有り]研究論文(学術雑誌)
- 2018年04月, Internal medicine (Tokyo, Japan), 57(8) (8), 1189 - 1189, 英語, 国内誌[査読有り]研究論文(学術雑誌)
- Background: Rhythm outcomes after the pulmonary vein isolation (PVI) using the cryoballoon (CB) are reported to be excellent. However, the lesions after CB ablation have not been well discussed. We sought to characterize and compare the lesion formation after CB ablation with that after radiofrequency (RF) ablation. Methods: A total of 42 consecutive patients who underwent PVI were enrolled (29 in the CB group and 13 in the RF group). The PVI lesions were assessed by late gadolinium enhancement magnetic resonance imaging 1-3 months after the PVI. The region around the PVs was divided into eight segments: roof, anterior-superior, anterior-carina, anterior-inferior, bottom, posterior-inferior, posterior-carina, and posterior-superior segment. The lesion width and lesion gap in each segment were compared between the two groups. Lesion gaps were defined as no-enhancement sites of >4 mm. Results: As compared to the RF group, the overall lesion width was significantly wider and lesion gaps significantly fewer at the anterior-superior segment of the left PV (LAS) and anterior-inferior segment of the right PV (RAI) in the CB group (lesion width: 8.2 ± 2.2 mm vs 5.6 ± 2.0 mm, P = .001; lesion gap at LAS: 7% vs 38%, P = .02; lesion gap at RAI: 7% vs 46%, P = .006). Conclusions: The PVI lesions after CB ablation were characterized by extremely wider and more continuous lesions than those after RF ablation.2018年04月, Journal of arrhythmia, 34(2) (2), 158 - 166, 英語, 国内誌[査読有り]研究論文(学術雑誌)
- A 72-year-old man with ischemic cardiomyopathy was referred to undergo an implantation of a cardiac implantable electrical device (CIED). A pocket was created subcutaneously on the left anterior chest. After the operation, he complained of severe pain irradiating to his left posterior shoulder. The local anesthetic nerve block by a local infusion of mepivacaine revealed the pain was associated with the supraclavicular nerve. We re-created the pocket and shifted the generator toward the inner side, and the irradiating pain vanished. A local anesthetic supraclavicular nerve block is an important option for the diagnosis of pain after a CIED implantation.2018年02月, Journal of arrhythmia, 34(1) (1), 84 - 86, 英語, 国内誌[査読有り]研究論文(学術雑誌)
- Elsevier Ltd, 2018年, Journal of Cardiology Cases, 18(3) (3), 95 - 98, 英語[査読有り]研究論文(学術雑誌)
- 2017年12月, JACC. Clinical electrophysiology, 3(12) (12), 1466 - 1467, 英語, 国際誌[査読有り]研究論文(学術雑誌)
- Elsevier B.V., 2017年12月, Journal of Arrhythmia, 33(6) (6), 646 - 648, 英語[査読有り]研究論文(学術雑誌)
- Transvenous lead extraction (TLE) is performed to prevent deaths in patients with device infections. Intracardiac masses detected by echocardiography, i.e., "ghosts," are reported in 8% of patients after a TLE in retrospective studies and in 14% in prospective studies. We herein describe a case with unusual ghosts after a TLE. Three-dimensional computed tomography (3DCT) is useful for revealing all the details of unusual ghosts. In this case, the residual silicone insulation and "cast," including the fibrous sheath and severe calcifications could be visualized and differentiated by 3DCT.2017年12月, Journal of arrhythmia, 33(6) (6), 640 - 642, 英語, 国内誌[査読有り]研究論文(学術雑誌)
- BACKGROUND: The relationship between pulmonary vein (PV) arrhythmogenicity and its anatomy has been reported. However, that of the superior vena cava (SVC) has not been well discussed. Arrhythmogenic response induced by pacing stimulation at SVC might help with identifying SVC arrhythmogenicity. The purpose of this study was to investigate the relationship between the anatomical dilatation of SVC and the arrhythmogenic response induced by pacing at SVC. METHODS: Forty-three patients who underwent atrial fibrillation (AF) ablation were enrolled in this study. After PV isolation, scan pacing (up to triple extra stimulation following intrinsic sinus beats) was performed at SVC. The arrhythmogenic response was defined as following: (1) repetitive atrial responses, (2) non-sustained, and (3) sustained AF/ atrial tachycardia. To assess the dilatation of SVC, we measured the cross-sectional area of the SVC (SVC-area) using multi-planar reconstruction CT imaging. RESULTS: Arrhythmogenic responses were documented in 24 patients (Group 1). No arrhythmogenic responses were documented in the remaining 19 patients (Group 2). The SVC-area was significantly larger in Group 1 than Group 2 (3.1±0.9 vs. 2.2±0.8 cm2, P=0.004). A multivariate analysis revealed only SVC-area was associated with arrhythmogenic responses (odds ratio=2.87, CI 1.05-7.82, P=0.04). Furthermore, AF recurrence rate was significantly higher in patients with SVC-area>2.56 cm2 than those with SVC-area <2.56 cm2 (9 [42.9%] of 21 vs. 3 [13.6%] of 22, P=0.026). CONCLUSION: Dilatation of SVC was associated with an arrhythmogenic response, and the AF recurrence rate was significantly higher in patients with large SVC-area. Adjunctive catheter intervention for the SVC might be indicated in patients with a dilated SVC and an arrhythmogenic response.2017年06月, Journal of arrhythmia, 33(3) (3), 177 - 184, 英語, 国内誌[査読有り]研究論文(学術雑誌)
- 2017年05月, JACC. Clinical electrophysiology, 3(5) (5), 526 - 527, 英語, 国際誌[査読有り]研究論文(学術雑誌)
- 2017年05月, HEART, 103(9) (9), 679 - 686, 英語[査読有り]研究論文(学術雑誌)
- Elsevier B.V., 2017年04月, Journal of Arrhythmia, 33(2) (2), 147 - 149, 英語[査読有り]研究論文(学術雑誌)
- 2017年03月, PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 40(3) (3), 301 - 309, 英語[査読有り]研究論文(学術雑誌)
- 2017年, INTERNAL MEDICINE, 56(14) (14), 1771 - 1779, 英語[査読有り]研究論文(学術雑誌)
- 2016年10月, PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 39(10) (10), 1090 - 1098, 英語[査読有り]研究論文(学術雑誌)
- Elsevier, 2016年06月, Journal of Arrhythmia, 32(3) (3), 230 - 232, 英語[査読有り]研究論文(学術雑誌)
- The coronary sinus is located within the inferior pyramidal space, which is the part of the epicardial visceral fibroadipose tissue wedging between the four cardiac chambers from the bottom of the heart. Therefore, this region is susceptible to the morphological changes of the cardiac chambers. We present a case of slit-like deformation of the coronary sinus orifice due to compression of the inferior pyramidal space by the severely dilated left ventricle, which has not been previously described.2016年05月, Pacing and clinical electrophysiology : PACE, 39(9) (9), 1026 - 9, 英語, 国際誌[査読有り]研究論文(学術雑誌)
- 2016年03月, Journal of cardiovascular electrophysiology, 27(10) (10), 1234 - 1235, 英語, 国際誌[査読有り]研究論文(学術雑誌)
- Elsevier, 2016年02月, Journal of Arrhythmia, 32(1) (1), 62 - 66, 英語研究論文(学術雑誌)
- BACKGROUND: To investigate the feasibility of substituting non-contrast-enhanced MR (non-CE-MR) imaging with a two-dimensional (2D) balanced steady-state free precession (b-SSFP) sequence for contrast-enhanced computed tomography (CE-CT) for atrial fibrillation (AF) ablation. METHODS: Fifty-four patients that underwent AF ablation under the guidance of a 3D electro-anatomical mapping system with CE-CT (n = 27) or non-CE-MR images (n = 27) were studied. Procedural results were compared between the two groups. Furthermore, in 22 patients who underwent both CE-CT and non-CE-MRI, two cardiologists independently scored the multiplanar reformatted images on a scale of 1 to 4 (from 1, poor, to 4, excellent). RESULTS: The image score was nearly 0.5 point higher with the CE-CT method. However, the procedural results such as the surface registration error (1.0 [0.8-1.6] mm versus 1.0 [0.8-1.35] mm, P = 0.88) and procedure time (185 [159-199] min versus 185 [142-221] min, P = 0.86) did not significantly differ between the CE-CT and non-CE-MR groups. CONCLUSION: The non-CE-MR method with a 2D-b-SSFP sequence can give us adequate information on AF ablation without any radiation exposure or contrast medium usage2016年02月, Journal of magnetic resonance imaging : JMRI, 43(2) (2), 495 - 503, 英語, 国際誌研究論文(学術雑誌)
- Elsevier, 2016年02月, Journal of Arrhythmia, 32(1) (1), 36 - 41, 英語[査読有り]研究論文(学術雑誌)
- 2015年11月, JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 26(11) (11), 1239 - 1246, 英語[査読有り]研究論文(学術雑誌)
- Elsevier B.V., 2015年08月, Journal of Arrhythmia, 31(4) (4), 252 - 254, 英語研究論文(学術雑誌)
- BACKGROUND: Usually, the pulmonary venous and left atrial (PV-LA) anatomy is assessed with contrast-enhanced computed tomographic imaging for catheter ablation of atrial fibrillation (AF). A non-contrast-enhanced magnetic resonance (MR) imaging method has not been established. Three-dimensional balanced steady-state free precession (3D b-SSFP) sequences cannot visualize the PV-LA anatomy simultaneously because of the signal intensity defect of pulmonary veins. We compared two-dimensional (2D) b-SSFP sequences with 3D b-SSFP sequences in depicting the PV-LA anatomy with non-contrast-enhanced MR imaging for AF ablation. METHODS: Eleven healthy volunteers underwent non-contrast-enhanced MR imaging with 3D b-SSFP and 2D b-SSFP sequences. The MR images were reconstructed on the 3D PV-LA surface image. Two experienced radiological technicians independently scored the multiplanar reformatted (MPR) images on a scale of 1-4 (from 1, not visualized, to 4, excellent definition). The overall score was a sum of 5 segments (LA and 4 PVs). RESULTS: In the 2D b-SSFP method, MR imaging was successfully performed, and the 3D PV-LA surface image was precisely reconstructed in all healthy volunteers. The image score was significantly higher in the 2D b-SSFP method compared to the 3D b-SSFP method (19 [19; 20] vs. 12 [11; 15], p=0.004, for both observers). No PV signal intensity defects occurred in the 2D b-SSFP method. CONCLUSIONS: The 2D b-SSFP sequence was more useful than the 3D b-SSFP sequence in adequately depicting the PV-LA anatomy.2015年08月, Journal of arrhythmia, 31(4) (4), 189 - 95, 英語, 国内誌研究論文(学術雑誌)
- Elsevier B.V., 2015年08月, Journal of Arrhythmia, 31(4) (4), 221 - 225, 英語[査読有り]研究論文(学術雑誌)
- Oxford University Press, 2015年07月, Europace, 17(9) (9), 1407 - 1414, 英語[査読有り]研究論文(学術雑誌)
- Elsevier, 2015年06月, Journal of Arrhythmia, 31(3) (3), 122 - 129, 英語[査読有り]研究論文(学術雑誌)
- Elsevier, 2015年06月, Journal of Arrhythmia, 31(3) (3), 152 - 158, 英語[査読有り]研究論文(学術雑誌)
- Elsevier, 2015年04月, Journal of Arrhythmia, 31(2) (2), 71 - 75, 英語[査読有り]研究論文(学術雑誌)
- BACKGROUND: Esophageal injury following catheter ablation of atrial fibrillation (AF) is reported to occur in 35% of patients. Even with a low energy setting (20-25 W), lesions develop in 10% of patients. Body mass index (BMI) has been reported to be a predictor of esophageal injury, indicating that patients with a low BMI (<24.9 kg/m(2)) are at a higher risk. We hypothesized that catheter ablation with a lower energy setting of 20 W controlled by esophageal temperature monitoring (ETM) at 39 °C could prevent esophageal injury even in patients with a BMI <24.9 kg/m(2). METHODS: Twenty patients with AF were included (age, 63±8 years; BMI, 22.9±1.3 kg/m(2), left atrium diameter, 44±11 mm). If the esophageal temperature probe registered a temperature of >39 °C, radiofrequency (RF) application was stopped immediately. RF application could be performed in a "point by point" manner for a maximum of 20 s. Endoscopy was performed 1-5 days after ablation. RESULTS: Esophageal mucosal injury was not observed in any patient in the study. CONCLUSIONS: Catheter ablation using ETM reduced the incidence of esophageal injuries, even in patients with a low BMI.2015年02月, Journal of arrhythmia, 31(1) (1), 12 - 7, 英語, 国内誌研究論文(学術雑誌)
- 2015年, Journal of Arrhythmia, 31(6) (6)研究論文(学術雑誌)
- BACKGROUND: The incidence of hematoma formation following implantation of a cardiovascular implantable electronic device (CIED) is estimated to be 5% even if a pressure dressing is applied. It is unclear whether a pressure dressing can really compress the pocket in different positions. Furthermore, the adhesive tape for fixing pressure dressings can tear the skin. We developed a new compression tool for preventing hematomas and skin erosions. METHODS AND RESULTS: We divided 46 consecutive patients receiving anticoagulation therapy who underwent CIED implantation into 2 groups (Group I: conventional pressure dressing, Group II: new compression tool). The pressure on the pocket was measured in both the supine and standing positions. The incidence of hematomas was compared between the 2 groups. The pressure differed between the supine and standing positions in Group I, but not in Group II (Group I: 14.8±7.1 mmHg vs. 11.3±9.9 mmHg, P=0.013; Group II: 13.5±2.8 mmHg vs. 13.5±3.5 mmHg, P=0.99). The incidence of hematomas and skin erosions was documented in 2 (8.7%) and 3 (13%) Group I patients, respectively. No complications were documented in Group II. CONCLUSIONS: The new compression tool can provide adequate continuous pressure on the pocket, regardless of body position. This device may reduce the incidence of hematomas and skin erosions after CIED implantation.2015年, Circulation journal : official journal of the Japanese Circulation Society, 79(8) (8), 1727 - 32, 英語, 国内誌研究論文(学術雑誌)
- Elsevier, 2015年, Journal of Arrhythmia, 31(5) (5), 286 - 292, 英語[査読有り]研究論文(学術雑誌)
- 2015年, MAGNETIC RESONANCE IN MEDICAL SCIENCES, 14(4) (4), 367 - 372, 英語[査読有り]研究論文(学術雑誌)
- Elsevier Inc., 2015年, HeartRhythm Case Reports, 1(2) (2), 41 - 45, 英語[査読有り]研究論文(学術雑誌)
- 2014年12月, Journal of Arrhythmia, 30(6) (6), 515 - 518研究論文(学術雑誌)
- 2014年12月, JOURNAL OF ARRHYTHMIA, 30(6) (6), 515 - 518, 英語研究論文(学術雑誌)
- Elsevier, 2014年12月, Journal of Arrhythmia, 30(6) (6), 491 - 495, 英語[査読有り]研究論文(学術雑誌)
- 2014年12月, CIRCULATION JOURNAL, 78(12) (12), 2993 - 2995, 英語[査読有り]研究論文(学術雑誌)
- (公財)日本心臓財団, 2014年11月, 心臓, 46(11) (11), 1538 - 1542, 日本語
- 2014年09月, JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 25(9) (9), 1032 - 1033, 英語[査読有り]研究論文(学術雑誌)
- 2014年07月, PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 37(7) (7), 874 - 883, 英語[査読有り]研究論文(学術雑誌)
- 2014年05月, PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 37(5) (5), 576 - 584, 英語[査読有り]研究論文(学術雑誌)
- (一社)日本不整脈心電学会, 2014年03月, 心電図, 33(5) (5), 421 - 428, 日本語
- 2013年12月, EUROPACE, 15(12) (12), 1798 - 1804, 英語[査読有り]研究論文(学術雑誌)
- 2013年10月, CIRCULATION JOURNAL, 77(10) (10), 2490 - 2496, 英語[査読有り]研究論文(学術雑誌)
- (一社)日本心臓病学会, 2013年09月, 日本心臓病学会誌, 8(Suppl.I) (Suppl.I), 426 - 426, 日本語拡張型心筋症における心臓MRIの遅延造影と心筋血流の低下との関連性の検討
- (一社)日本不整脈心電学会, 2013年09月, 心電図, 33(Suppl.4) (Suppl.4), S - 139, 日本語CHA2DS2-VASc score=0の非弁膜症性心房細動症例に対する新規抗凝固薬使用に関する検討
- 2013年09月, JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY, 37(3) (3), 223 - 231, 英語[査読有り]研究論文(学術雑誌)
- (一社)日本不整脈心電学会, 2012年09月, 心電図, 32(Suppl.5) (Suppl.5), S - 155, 日本語冠攣縮性狭心症患者におけるJ波と心室細動の関連についての検討
- (一社)日本不整脈心電学会, 2012年09月, 心電図, 32(Suppl.5) (Suppl.5), S - 157, 日本語冠攣縮とJ波の経時的変化が観察された心肺蘇生後の1例
- 2012年08月, CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 5(4) (4), 667 - 675, 英語[査読有り]研究論文(学術雑誌)
- (一社)日本不整脈心電学会, 2012年05月, Journal of Arrhythmia, 28(Suppl.) (Suppl.), 257 - 257, 日本語
- (一社)日本不整脈心電学会, 2012年05月, Journal of Arrhythmia, 28(Suppl.) (Suppl.), 367 - 367, 日本語
- (一社)日本不整脈心電学会, 2012年05月, Journal of Arrhythmia, 28(Suppl.) (Suppl.), 375 - 375, 日本語
- (一社)日本不整脈心電学会, 2012年05月, Journal of Arrhythmia, 28(Suppl.) (Suppl.), 403 - 403, 日本語
- Objectives: We sought to investigate the relationship between the size of the left atrial (LA) isolated surface area (ISA) after pulmonary vein antrum isolation (PVAI) for paroxysmal atrial fibrillation (AF) and rhythm outcome after a 12 month follow up. Methods: One-hundred-one consecutive patients with paroxysmal AF after PVAI were enrolled. ISA was expressed as the proportion of isolated surface areas (cm2), i.e. the isolated antral regions of the LA excluding the PVs, to the sum of the surface areas of the antral regions plus the surface of the posterior wall (cm2) taking into consideration the individual antral anatomy. All surface areas were assessed using a special software of the NavX system. Patients were arbitrarily divided into four groups according to ISA (Group I: <50%, group II: 50 to <60%, group III: 60 to <70%, group IV: ≥70%). Results: In Kaplan-Meier analysis, recurrence rate was significantly lower in group III and group IV, respectively, as compared to group I (p<0.03 for both comparisons). According to receiver-operator characteristic curve analysis, the optimal cutoff value of ISA was 55%. Conclusion: After 12 months, a larger ISA was associated with a significantly lower AF/MRT recurrence rate. ISA ≥55% might serve as a predictor for long-term success after PVAI.Japanese Heart Rhythm Society, 2011年, Journal of Arrhythmia, 27, OP56_5 - OP56_5, 英語
- 2008年09月, PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 31(9) (9), 1160 - 1167, 英語Upper turnover portion of the reentry circuit for typical and reverse typical atrial flutter[査読有り]研究論文(学術雑誌)
- 2008年, Kobe Journal of Medical Sciences, 54(2) (2), E122 - E135, 英語Endocardial substrate mapping for monomorphic ventricular tachycardia ablation in ischemic and non-ischemic cardiomyopathy[査読有り]研究論文(学術雑誌)
- 2007年, Circulation Journal, 71(10) (10), 1599 - 1605, 英語[査読有り]研究論文(学術雑誌)
- Blackwell Publishing Inc., 2020年11月01日, Journal of Cardiovascular Electrophysiology, 31(11) (11), 3069 - 3070, 英語速報,短報,研究ノート等(学術雑誌)
- (一社)日本循環器学会, 2019年03月, 日本循環器学会学術集会抄録集, 83回, CP27 - 3, 日本語遠隔モニタリング診療を受けている心臓デバイス(ICD、CRT-D)植込み患者の心理社会的特徴の検討
- (一社)日本循環器学会, 2017年03月, 日本循環器学会学術集会抄録集, 81回, SY15 - 3, 英語不整脈治療の新展開 DE-MRIガイド下カテーテルアブレーション(DE-MRI Guided Catheter Ablation)
- (一社)日本循環器学会, 2017年03月, 日本循環器学会学術集会抄録集, 81回, PJ - 246, 英語心外膜アブレーションに使用する上腹壁動脈の解剖学的特性(Anatomical Feature of the Superior Epigastric Artery for Epicardial Ablation)
- 2017年, 日本循環器学会近畿地方会(Web), 123rd心筋浸潤による急性心不全を合併した菌状息肉症の一剖検例
- 2016年, 日本循環器学会近畿地方会(Web), 122nd2回のリード抜去を要した後にシリコン被膜が残存し開胸にて摘出となったデバイス感染の一例
- 2016年, 日本循環器学会近畿地方会(Web), 122nd術前CTによる穿刺シミュレーションが安全な心外膜VTアブレーションに有用であった一例
- 2013年11月, CIRCULATION, 128(22) (22), 英語Rescue Catheter Ablation for Electrical Storm due to Ventricular Tachycardia Can Reduce Ventricular Tachycardia and Electrical Storm Recurrence in Patients With Non-ischemic Cardiomyopathy研究発表ペーパー・要旨(国際会議)
- 2013年04月, Europace, 15(4) (4), 565, 英語速報,短報,研究ノート等(学術雑誌)
- 2013年, 日本循環器学会近畿地方会(Web), 115th房室結節回帰性頻拍(AVNRT)におけるantegrade slow pathway(ASP)の電気生理的局在に関する検討
- 2012年11月, CIRCULATION, 126(21) (21), 英語Safety and Efficacy of Catheter Ablation of Atrial Fibrillation Using an Esophageal Temperature Monitoring in the Patients with a Small BMI研究発表ペーパー・要旨(国際会議)
- 2012年11月, CIRCULATION, 126(21) (21), 英語A Simple Anatomical Index Predicting the Patients Suitable for Catheter Ablation of Atrial Fibrillation研究発表ペーパー・要旨(国際会議)
- 2012年11月, CIRCULATION, 126(21) (21), 英語Visualization of the Antegrade Slow and Fast Pathway Input Using 3D Electro-Anatomical Mapping System in the Patients with Atrioventricular Nodal Reentrant Tachycardia研究発表ペーパー・要旨(国際会議)
- 2012年11月, CIRCULATION, 126(21) (21), 英語Prediction of Response to Cardiac Resynchronization Therapy Using Improvement of Coronary Flow Reserve in Patients with Non-Ischemic Cardiomyopathy研究発表ペーパー・要旨(国際会議)
- 2012年, 日本循環器学会近畿地方会(Web), 113th冠静脈洞閉鎖を合併した房室結節リエントリー性頻拍の1例
- 社団法人日本循環器学会, 2007年03月01日, Circulation journal : official journal of the Japanese Circulation Society, 71, 90 - 90, 英語2 Identification of the Right ventricular Pacing Site for Cardiac Resynchronization Therapy (CRT) Guided by Electroanatomical Mapping (CARTO)(Identification Strategy and Treatment Approach of the Non-responder Group in Patients Withcardiac Resynchronization Therapy using biventricular Pacing, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- 社団法人日本循環器学会, 2006年10月20日, Circulation journal : official journal of the Japanese Circulation Society, 70, 1220 - 1220, 日本語44)多発性心室性期外収縮を有する心機能低下例にカテーテルアブレーションを施行し,心機能改善を認めた1例(第101回日本循環器学会近畿地方会)
- 社団法人日本循環器学会, 2006年04月20日, Circulation journal : official journal of the Japanese Circulation Society, 70, 1119 - 1119, 日本語120)DDDペーシングによりelectrical stormを回避できた心室中部閉塞(MVO)を伴う肥大型心筋症の1例(第100回日本循環器学会近畿地方会)
- 社団法人日本循環器学会, 2006年04月20日, Circulation journal : official journal of the Japanese Circulation Society, 70, 1118 - 1118, 日本語111)心不全改善後のelectrical stormに対しアブレーションを施行したALアミロイドーシスの1例(第100回日本循環器学会近畿地方会)
- (公財)日本心臓財団, 2006年04月, 心臓, 38(4) (4), 354 - 359, 日本語
- 社団法人日本循環器学会, 2006年03月01日, Circulation journal : official journal of the Japanese Circulation Society, 70, 373 - 373, 英語PE-155 Endocardial Substrate Mapping and Ablation for Monomorphic Ventricular Tachycardia in Patients with Ischemic and Nonischemic Cardiomyopathy(Arrhythmia, therapy-11 (A) PE26,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- 社団法人日本循環器学会, 2006年03月01日, Circulation journal : official journal of the Japanese Circulation Society, 70, 529 - 529, 英語PJ-159 The Early Effects of Carvediol Therapy on Beat-to-beat QT dispersion in Patients with Congestive Heart Failure(ECG/Body surface potential mapping/Holter-6 () PJ27,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- 社団法人日本循環器学会, 2006年03月01日, Circulation journal : official journal of the Japanese Circulation Society, 70, 468 - 469, 英語PE-544 Efficacy of Burst Pacing Set in 91% of Cycle-length, 13 Pulses for Ventricular Tachycardia in Patents with Implantable Cardioverter-Defibrillator(Arrhythmia, therapy-13 (A) PE92,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- 社団法人日本循環器学会, 2005年10月20日, Circulation journal : official journal of the Japanese Circulation Society, 69, 975 - 975, 日本語家族性肥大型心筋症の2例, 除細動器の予防的埋込の適応について(第99回日本循環器学会近畿地方会)
- 社団法人日本循環器学会, 2005年03月01日, Circulation journal : official journal of the Japanese Circulation Society, 69, 631 - 632, 英語Risk Stratification for Cardiac Events in Patients with Organic Heart Disease and Low Ejection Fraction Using Beat-to-Beat QT Dispersion (ECG/Body Surface Potential Mapping/Holter 7 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- 社団法人日本循環器学会, 2005年03月01日, Circulation journal : official journal of the Japanese Circulation Society, 69, 257 - 257, 英語Radiofrequency Catheter Ablation for Drug Refractory Electrical Storm in Implantable Cadioverter Defibrillator Recipients(Arrhythmia, Non-pharmacological Therapy 7 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- 社団法人日本循環器学会, 2005年03月01日, Circulation journal : official journal of the Japanese Circulation Society, 69, 399 - 399, 英語Examination of Optimal Right Ventricular Pacing Site for Cardiac Resynchronization Therapy Guided by Electroanatomical Mapping(Heart Failure, Clinical 9 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- (一社)日本循環器学会, 2004年04月, Circulation Journal, 68(Suppl.II) (Suppl.II), 815 - 815, 日本語
- 社団法人日本循環器学会, 2004年03月01日, Circulation journal : official journal of the Japanese Circulation Society, 68, 194 - 194, 英語OE-221 Radiofrequency Catheter Ablation Guided by Electro-Anatomical Maps (CARTO System) for Un-mappable Ventricular Tachycardia(Arrhythmia, Non-Pharmacological Therapy 9 (A) : OE27)(Oral Presentation (English))
- 社団法人日本循環器学会, 2004年03月01日, Circulation journal : official journal of the Japanese Circulation Society, 68, 578 - 578, 英語PJ-400 The Predictive Value of Beat-to-Beat QT Dispersion for Stratifying Arrhythmic Risk in Ischemic Heart Disease(ECG/Body Surface Potential Mapping/Holler 5 (A) : PJ67)(Poster Session (Japanese))
- (一社)日本循環器学会, 2003年10月, Circulation Journal, 67(Suppl.III) (Suppl.III), 977 - 977, 日本語
- (一社)日本循環器学会, 2003年10月, Circulation Journal, 67(Suppl.III) (Suppl.III), 982 - 982, 日本語
- (一社)日本循環器学会, 2003年04月, Circulation Journal, 67(Suppl.II) (Suppl.II), 819 - 819, 日本語
- Taipei-Tokyo-Seoul Arrhythmia Joint Conference 2021, 2021年09月, 英語LGE and AF rotor[招待有り]口頭発表(招待・特別)
- 第83回日本循環器学会学術集会, 2019年03月, 日本語, 日本循環器学会, 横浜, 国内会議遠隔モニタリング診療を受けている心臓デバイス(ICD、CRTD)植込み患者の心理社会的特徴の検討ポスター発表
- 第83回日本循環器学会学術集会, 2019年03月, 日本語, 横浜市, 国内会議遠隔モニタリング診療を受けている心臓デバイス(ICD/CRTD)植込み患者の心理社会的特徴の検討(第2報).ポスター発表
- 第83回日本循環器学会学術集会, 2019年03月, 英語, 日本循環器学会, 横浜, 国内会議The lesion distribution after pulmonary vein isolation using balloon catheter : LGE-MRI analysis口頭発表(一般)
- 第83回日本循環器学会学術集会, 2019年03月, 日本語, 日本循環器学会, 横浜, 国内会議The Correlation between Circulating Intermediate CD14++CD16+Monocytes and Atrial Electrical Remodeling in Atrial Fibrillation Patientsポスター発表
- 第83回日本循環器学会学術集会, 2019年03月, 日本語, 日本循環器学会, 横浜, 国内会議The Characteristics of Onset Timing of the Coronary Artery Spasm during an Atrial Fibrillation Ablation Procedure口頭発表(一般)
- 第83回日本循環器学会学術集会, 2019年03月, 英語, 日本循環器学会, 横浜, 国内会議Lesion characteristics assessed by LGE-MRI between cryo-balloon ablation and radiofrequency ablation with contact-force sensing catheter口頭発表(一般)
- 第83回日本循環器学会学術集会, 2019年03月, 英語, 日本循環器学会, 横浜, 国内会議Impact of Different Radiofrequency Power Settings on Tissue Temperature Profiles Under the Same Ablation Index口頭発表(一般)
- 第83回日本循環器学会学術集会, 2019年03月, 日本語, 日本循環器学会, 横浜, 国内会議Impact of Anisotropic Conduction Property in the Left Atrium following Pulmonary Vein Isolation on the Inducibility of Atrial Tachycardia口頭発表(一般)
- 第83回日本循環器学会学術集会, 2019年03月, 英語, 日本循環器学会, 横浜, 国内会議Feasibility of Imaging Fibrotic Substrates in the Left Atrium using LGE-MRI Technologyシンポジウム・ワークショップパネル(公募)
- 第83回日本循環器学会学術集会, 2019年03月, 英語, 日本循環器学会, 横浜, 国内会議A Novel Unshielded Magnetocardiography System: The 1st Performance Test in 25 Healthy Male Volunteers口頭発表(一般)
- 第11回植込みデバイス関連冬季大会, 2019年02月, 日本語, 日本不整脈心電学会, 東京, 国内会議長期植込み後に心理的負担によってICD全システム抜去に至った一例口頭発表(一般)
- 第47回人工心臓と補助循環懇話会学術集会, 2019年02月, 日本語, 佐賀, 症例は 47 歳女性。20 歳代より労作時呼吸困難を自覚し、39 歳時分娩 中に急性左心不全を発症した。心エコーにて左室拡大を伴うびまん性左 室収縮能低下を認め、拡張型心筋症と考え内服加療を開始したが心機能 の改善を認めず、41 歳時に機能性僧帽弁閉鎖不全症に対して、僧帽弁置 換術および三尖弁輪形成術を施行した。また持続性心室頻拍に対して、 同年 ICD 植込み術を施行した。45 歳時より NYHAⅢ-Ⅳの状態が続き、 BNP 1000-1500pg/mL と高値で推移した。46 歳時に精査加療目的で入院後、 強心剤依存の状態となり、心臓移植適応登録後、同年 11 月植込型左室 補助人工心臓(LVAD)装着術を施行した。術直後は良好な循環動態であっ たが、術後 1 日目より心電図波形が著明な低電位となり、心室頻拍(VT) が出現した。電気的除細動に加, 国内会議拡張型心筋症に対して植え込み型左室補助人工心臓装着術後、難治性心室頻拍と右心不全加療に難渋した一例ポスター発表
- カテーテルアブレーション関連秋季大会2018, 2018年11月, 日本語, 日本不整脈心電学会, 沖縄, 国内会議不顕性副伝導路を介するPseudo VTの一例口頭発表(一般)
- 第126回日本循環器学会 近畿地方会, 2018年11月, 日本語, 大阪, 国内会議僧帽弁機械弁置換術,Maze 術後の僧帽弁輪を旋回する心房頻拍に冠静脈洞内での通電が有効であった一例口頭発表(一般)
- カテーテルアブレーション関連秋季大会2018, 2018年11月, 日本語, 日本不整脈心電学会, 沖縄, 国内会議下大静脈-三尖弁輪峡部通電により右冠動脈の血腫圧排,閉塞をきたした1 例 ~血管内超音波と3次元CTからの考察~口頭発表(一般)
- カテーテルアブレーション関連秋季大会2018, 2018年11月, 日本語, 日本不整脈心電学会, 沖縄, 国内会議ICD適切作動を伴うVF発作に対しカテーテルアブレーションが奏功したBrugada症候群の1例ポスター発表
- カテーテルアブレーション関連秋季大会2018, 2018年11月, 日本語, 日本不整脈心電学会, 沖縄, 国内会議7年の経過で心内膜面不整脈基質の著名な悪化を認めた拡張相肥大型心筋症の1例ポスター発表
- 11th Asia Pacific Heart Rhythm Society Scientific Session, 2018年10月, 英語, Asia Pacific Heart Rhythm Society, 台北, 国際会議LGE-MRI or Delayed Enhancement-MRI in Diagnosis of Arrhythmogenesis[招待有り]口頭発表(招待・特別)
- 第65回日本不整脈心電学会学術大会, 2018年07月, 英語, 日本不整脈心電学会, 東京, 国内会議The lesion characteristics assessed by LGE-MRI after the cryoballoon ablation and radiofrequency ablation with contact-force sensing catheter口頭発表(一般)
- 第65回日本不整脈心電学会学術大会, 2018年07月, 英語, 日本不整脈心電学会, 東京, 国内会議The correlation between circulating intermediate CD14++CD16+monocytes and atrial electrical remodeling in AF patientsポスター発表
- 第126回 日本循環器学会近畿地方会, 2018年06月, 日本語, 大阪, 国内会議長期植込み後に心理的負担によってICD抜去に至った一例口頭発表(一般)
- 第126回 日本循環器学会近畿地方会, 2018年06月, 日本語, 日本循環器学会, 大阪, 国内会議神戸大学医学部附属病院でのリード抜去の現状口頭発表(一般)
- 第126回 日本循環器学会近畿地方会, 2018年06月, 日本語, 日本循環器学会, 大阪, 国内会議心機能低下並びに中等度三尖弁逆流症を併発した長期持続性心房細動に対してHis束ペーシングを導入した1症例口頭発表(一般)
- 第126回 日本循環器学会近畿地方会, 2018年06月, 日本語, 日本循環器学会, 大阪, 国内会議冠静脈洞瘤を合併したWPW 症候群に対し,解剖学的情報がアブレーションに有用であった1例口頭発表(一般)
- 第82回日本循環器学会学術集会, 2018年03月, 英語, 日本循環器学会, 大阪, 国内会議The Report of Initial Analysis of HYOGO ATRIAL FIBRILLATION NETWORK (HAF-NET)口頭発表(一般)
- 第82回日本循環器学会学術集会, 2018年03月, 英語, 日本循環器学会, 大阪, 国内会議The Relationship between Lesion Gap Detected by Late-gadolinium Enhancement Magnetic Resonance Imaging and Recurrence of Atrial Fibrillation after Cryo-balloon Ablation口頭発表(一般)
- 第10回日本不整脈心電学会植込みデバイス関連冬季大会, 2018年02月, 日本語, 日本不整脈心電学会, 横浜, 国内会議当院における着用型自動除細動器の使用経験と有用性の検討口頭発表(一般)
- 第10回日本不整脈心電学会植込みデバイス関連冬季大会, 2018年02月, 日本語, 日本不整脈心電学会, 横浜, 国内会議心室細動蘇生例に対しS-ICD植込み後、左脚後枝領域起源心室頻 拍が原因と推測されアブレーションを行った1例ポスター発表
- 第10回日本不整脈心電学会植込みデバイス関連冬季大会, 2018年02月, 日本語, 日本不整脈心電図学会, 横浜, 国内会議自動閾値測定の使用下で右室単独ペーシングを生じて血行動態が破綻した拡張型心筋症,CRTD 交換後の 1 例口頭発表(一般)
- 第10回植込みデバイス関連冬季大会, 2018年02月, 日本語, 横浜, 国内会議デバイス植込み患者の遠隔モニタリング診療に対する看護支援効果に関する検証的臨床研究-第1報-口頭発表(一般)
- 第10回日本不整脈心電学会植込みデバイス関連冬季大会, 2018年02月, 日本語, 日本不整脈心電学会, 横浜, 国内会議デバイス植え込み患者の遠隔モニタリング診療に対する看護支援効果に関する検証的臨床研究口頭発表(一般)
- 第10回日本不整脈心電学会植込みデバイス関連冬季大会, 2018年02月, 日本語, 日本不整脈心電学会, 横浜, 国内会議CRTD植込み後の疼痛に対して、局所麻酔による神経ブロックにて鎖骨上神経の関与を診断し、対処した一例[招待有り]口頭発表(招待・特別)
- 第124回日本循環器学会近畿地方会, 2017年11月, 日本語, 日本循環器学会, 大阪, 国内会議当院における着用型自動除細動器の使用経験と使用法の検討口頭発表(一般)
- 第124回日本循環器学会近畿地方会, 2017年11月, 日本語, 日本循環器学会, 大阪, 国内会議心房中隔欠損症を伴う心房細動に対する治療戦略口頭発表(一般)
- 第124回日本循環器学会近畿地方会, 2017年11月, 日本語, 日本循環器学会, 大阪, 国内会議心房細動による皮下植込み型除細動器 (S-ICD)の不適切作動をきたした肥大型心筋症の1例口頭発表(一般)
- 第124回日本循環器学会近畿地方会, 2017年11月, 日本語, 日本循環器学会, 大阪, 国内会議自動閾値測定の使用下で右室単独ペーシングを生じて血行動態が破綻した、拡張型心筋症、CRTD交換後の一例口頭発表(一般)
- 第124回日本循環器学会近畿地方会, 2017年11月, 日本語, 日本循環器学会, 大阪, 国内会議右室ペーシングが診断に有用であった右脚ブロックを伴うブルガダ症候群の一例口頭発表(一般)
- AHA Scientifi Sessions 2017, 2017年11月, 英語, American Heart Association, Anaheim, USA, 国際会議Relationship Between The Lesion Gap Assessed By DE-MRI And The Re-conduction Site In 2nd AF Ablation Procedureポスター発表
- 第124回日本循環器学会近畿地方会, 2017年11月, 日本語, 日本循環器学会, 大阪, 国内会議CRTD植込み後疼痛に対し、局所麻酔による神経ブロックにて鎖骨上神経の関与を 証明し、対処した一例口頭発表(一般)
- AHA Scientific Sessions 2017, 2017年11月, 英語, American Heart Association, Anaheim, USA, 国際会議Anatomical Characteristics of the Superior Epigastric Artery for Epicardial Radiofrequency Catheter Ablationポスター発表
- 第64回日本不整脈心電学会学術大会/第12回アジア太平洋不整脈学会学術集会, 2017年09月, 日本語, 日本不整脈心電学会/Asia Pacific Rhythm Society, 横浜, 国際会議The Therapeutic Strategies for The Patients with both Atrial Fibrillation and Atrial Septal Defect ; Cather Based or Surgical Approachポスター発表
- 第64回日本不整脈心電学会学術大会/第15回アジア太平洋不整脈学会学術集会, 2017年09月, 日本語, 日本不整脈心電学会/Asia Pacific Rhythm Society, 横浜市, 国際会議The Report of Initial Analysis of HYOGO ATRIAL FIBRILLATION NETWORKThe Report of Initial Analysis of HYOGO ATRIAL FIBRILLATION NETWORKポスター発表
- 第64回日本不整脈心電学会学術大会/第11回アジア太平洋不整脈学会学術集会, 2017年09月, 英語, 日本不整脈心電学会/Asia Pacific Rhythm Society, 横浜, 国際会議The lesion gap assessed by DE-MRI could predict the re-conduction site in 2nd AF ablation procedure口頭発表(一般)
- 第64回日本不整脈心電学会学術大会/第10回アジア太平洋不整脈学会学術集会, 2017年09月, 英語, 日本不整脈心電学会/Asia Pacific Rhythm Society, 横浜, 国際会議Pericardiocentesis with a Modified Anterior Approach not passing through the Abdominal Cavity, Confirmation from Post-procedural Computed Tomography口頭発表(一般)
- 第64回日本不整脈心電学会学術大会, 2017年09月, 英語, 日本不整脈心電学会, 横浜, 国内会議Optimal Angulations for Obtaining an en Face View of Each Coronary Aortic Sinus and the Ventricular Septumポスター発表
- 第64回日本不整脈心電学会学術大会/第13回アジア太平洋不整脈学会学術集会, 2017年09月, 英語, 日本不整脈心電学会/Asia Pacific Rhythm Society, 横浜, 国際会議Influence of Left Axis Deviation in Patients with Left Bundle Block on the Response to Cardiac Resynchronization Therapyシンポジウム・ワークショップパネル(公募)
- 第64回日本不整脈心電学会学術大会, 2017年09月, 英語, 日本不整脈心電学会, 横浜, 国内会議Clinical Structural Anatomy of the Triangle of Koch Reconstructed from the Living Heart Using Multidetector-row Computed Tomographyポスター発表
- 第64回日本不整脈心電学会学術大会/第14回アジア太平洋不整脈学会学術集会, 2017年09月, 英語, 日本不整脈心電学会/Asia Pacific Rhythm Society, 横浜, 国際会議Accuracy of detecting re-conduction site after cryo-balloon ablation by using delayed enhancement magnetic resonance imaging口頭発表(一般)
- カテーテルアブレーション関連大会2017, 2017年07月, 日本語, 日本不整脈心電学会, 札幌, 国内会議二度の心外膜カテーテルアブレーションを要した不整脈原性右室心筋症の一例口頭発表(一般)
- カテーテルアブレーション関連大会2017, 2017年07月, 日本語, 日本不整脈心電学会, 札幌, 国内会議遅延造影MRIが頻拍回路の同定に有用であった持続性心房細動アブレーション慢性期に再発した心房頻拍の一例口頭発表(一般)
- カテーテルアブレーション関連大会2017, 2017年07月, 日本語, 日本不整脈心電学会, 札幌, 国内会議左室心外膜側にspotty な不整脈器質を 同定しアブレーションに成功した 心サルコイドーシスの1例口頭発表(一般)
- 第32回日本皮膚悪性腫瘍学会学術大会, 2017年06月, 日本語, 日本悪性腫瘍学会, 秋田, 国内会議心筋浸潤により心タンポナーデ、心不全を呈した菌状息肉症の1例口頭発表(一般)
- The Heart Rhythm Society's 38th Annual Scientific Sessions, 2017年05月, 英語, Heart Rhythm Society, シカゴ, アメリカ, 国際会議Extracardiac compression of the inferolatral branch of the coronary vein by the descending aorta in a case with dilated cardiomyopathyポスター発表
- The Heart Rhythm Society's 38th Annual Scientific Sessions, 2017年05月, 英語, Heart Rhythm Society, シカゴ, アメリカ, 国際会議Distribution of inflammation immediately after cryoballoon ablation in patient with atrial fibrillationポスター発表
- 第81回日本循環器学会学術集会, 2017年03月, 英語, 日本循環器学会, 金沢, 国内会議When Should We Perform the Delayed-Enhancement MRI for Visualizing the Lesion after the Cryo-balloon Ablation?ポスター発表
- 第81回日本循環器学会学術集会, 2017年03月, 英語, 日本循環器学会, 金沢, Backgrounds: Patients with left bundle block (LBBB) derive great benefits from cardiac resynchronization therapy (CRT), however, some obtain little or no benefit. LBBB is diagnosed by conventional criteria but it contains some variables, such as axis deviation. These can affect the ventricular activation difference and the response to CRT. We investigated the impact of left axi, 国内会議The Impact of Left Axis Deviation in Patients with Left Bundle Brunch Block on the Response to Cardiac Resynchronization Therapyポスター発表
- 第81回日本循環器学会学術集会, 2017年03月, 英語, 日本循環器学会, 金沢, 国内会議The Difference of the Lesion Formation After Pulmonary Vein Isolation Using the Cryoballoon and the Conventional Radiofrequency Ablation DE-MRI Analysisポスター発表
- 第81回日本循環器学会学術集会, 2017年03月, 日本語, 日本循環器学会, 金沢, 国内会議DE-MRI guided catheter ablationシンポジウム・ワークショップパネル(公募)
- 第83回日本循環器学会学術大会, 2017年03月, 英語, 日本循環器学会, 金沢, 国内会議Anatomical Feature of the Superior Epigastric Artery for Epicardial Ablationポスター発表
- 第81回日本循環器学会学術集会, 2017年03月, 日本語, 日本循環器学会, 金沢, 国内会議Anatomical Feature of the Superior Epigastric Artery for Epicardial Ablationポスター発表
- 第9回植込みデバイス関連冬季大会, 2017年02月, 日本語, 日本不整脈心電学会, 大阪, 国内会議透視では確認できないシリコン被膜が残存し、2回のリード抜去を要した後に開胸にて摘出となったデバイス感染の一例口頭発表(一般)
- 第9回植込みデバイス関連冬季大会, 2017年02月, 日本語, 日本不整脈心電学会, 大阪, 国内会議劇症型心筋炎による心室細動症例にWCDを使用した1例口頭発表(一般)
- 第122回日本循環器学会近畿地方会, 2016年11月, 日本語, 日本循環器学会近畿支部, 大阪, 国内会議透視では確認できないシリコン被膜が残存し、2回のリード抜去を要した後に開胸にて摘出となったデバイス感染の一例口頭発表(一般)
- 第122回日本循環器学会近畿地方会, 2016年11月, 日本語, 日本循環器学会, 大阪, 国内会議術前CTによる穿刺シミュレーションが安全な心外膜VTアブレーションに有用であった一例口頭発表(一般)
- 第124回日本循環器学会近畿地方会, 2016年11月, 日本語, 日本循環器学会, 大阪, 国内会議下行大動脈が左室基部側下側壁を拡張期に圧迫しCRTD左室リード留置標的血管の扁平化を認めた一例ポスター発表
- 第122回日本循環器学会近畿地方会, 2016年11月, 日本語, 日本循環器学会, 大阪, 国内会議Lesion formation after pulmonary vein isolation using the cryoballoon and the conventional radiofrequency ablation: Delayed-enhancement MRI analysis口頭発表(一般)
- カテーテルアブレーション関連大会2016, 2016年10月, 日本語, 日本不整脈心電学会, 福岡, 国内会議Narrow QRS でHis近傍にexitがあるため、診断と治療に苦慮した、心サルコイドーシスによる心室頻拍の1例口頭発表(一般)
- 第63回日本不整脈心電学会学術大会, 2016年07月, 日本語, 日本不整脈心電学会, 札幌, 国内会議The relation between blood glucose fluctuation and arrhythmia in patients with type 1 diabetes mellitus口頭発表(一般)
- 第63回日本不整脈心電学会学術大会, 2016年07月, 日本語, 日本不整脈心電学会, 札幌, 国内会議The dilated superior vena cava associating with arrhythmogenic activity in patients with atrial fibrillation口頭発表(一般)
- 第63回日本不整脈心電学会学術大会, 2016年07月, 英語, 日本不整脈心電学会, 札幌, 国内会議Radiofrequency Catheter Ablation for Drug Refractory Electrical Storm of Monomorphic Ventricular Tachycardia Targeting Arrhythmogenic Substrate口頭発表(一般)
- 第63回日本不整脈心電学会学術大会, 2016年07月, 日本語, 日本不整脈心電学会, 札幌, 国内会議Quantitative analysis of Isolation Area and Rhythm Outcome after Pulmonary Vein Isolation including Selected CFAE Area around Pulmonary Vein in Patient with Persistent Atrial Fibrillationポスター発表
- 第63回日本不整脈心電学会学術大会, 2016年07月, 日本語, 日本不整脈心電学会, 札幌, 国内会議Pulmonary vein isolation without pulmonary venographyポスター発表
- 第63回日本不整脈心電学会学術大会, 2016年07月, 英語, 日本不整脈心電学会, 札幌, 国内会議Predictors on Long-term Maintenance of Left Ventricular Reverse Remodeling in Respnders at 6 Months to Cardiac Resynchronization Therapyシンポジウム・ワークショップパネル(公募)
- 第63回日本不整脈心電学会学術大会, 2016年07月, 英語, 日本不整脈心電学会, 札幌, 国内会議Lesion formation after pulmonary vein isolation using the cryoballoon and the conventional radiofrequency ablation: Delayed-enhancement MRI analysis口頭発表(一般)
- 第63回日本不整脈心電学会学術大会, 2016年07月, 日本語, 日本不整脈心電学会, 札幌, 国内会議Isolation area after Cryo-balloon ablation and cross-sectional area of pulmonary vein ostiumポスター発表
- 第63回日本不整脈心電学会学術大会, 2016年07月, 日本語, 日本不整脈心電学会, 札幌, 国内会議case series of anti-mitochondrial antibody M2 associated cardiomyopathyポスター発表
- 第80回 日本循環器学会 学術集会, 2016年03月, 英語, 日本循環器学会, 仙台, 国内会議The effectiveness and the safety of epicardial radiofrequency catheter ablation for drug and endocardial ablation refractory ventricular tachycardiaポスター発表
- 第80回 日本循環器学会 学術集会, 2016年03月, 英語, 日本循環器学会, 仙台, 国内会議The correlation between the area of complex fractionated atrial electrograms and the atrial defibrillation threshold in patients with persistent atrial fibrillationポスター発表
- 第80回 日本循環器学会 学術集会, 2016年03月, 英語, 日本循環器学会, 仙台, 国内会議Radiofrequency Catheter Ablation for Drug Refractory Electrical Storm of Monomorphic Ventricular Tachycardia in Patients with Structural Heart Disease口頭発表(一般)
- 第80回 日本循環器学会 学術集会, 2016年03月, 英語, 日本循環器学会, 仙台, 国内会議Long-term Maintenance of Left Ventricular Reverse Remodeling Achieved by Cardiac Resynchronization Therapyポスター発表
- 第80回 日本循環器学会 学術集会, 2016年03月, 英語, 日本循環器学会, 仙台, 国内会議Anti-mitochondrial M2 Antibody Positive is a Risk Factor for Atrial Arrhythmia with Impaired Hepatic Function口頭発表(一般)
- 第80回 日本循環器学会 学術集会, 2016年03月, 英語, 日本循環器学会, 仙台, 国内会議Anatomical dilatation of Superior Vena Cava (SVC) associated with an arrhythmogenic activity induced by SVC scan pacingポスター発表
- 第8回植込みデバイス関連冬期大会 デバイス研究会, 2016年02月, 日本語, 日本不整脈学会, 小倉, 国内会議修正大血管転位症例に心臓再同期療法を施行した1例口頭発表(一般)
- 第8回植込みデバイス関連冬期大会 デバイス研究会, 2016年02月, 日本語, 日本不整脈学会, 小倉, 国内会議リード断端が心房内に遺残し鼠径部より経皮的に抜去し得た一症例ポスター発表
- 第8回植込みデバイス関連冬期大会 デバイス研究会, 2016年02月, 日本語, 日本不整脈学会, 小倉, 国内会議DDDペースメーカ留置後に頻回にspike on Tを来した1例口頭発表(一般)
- 8th ASIA PACIFIC HEART RHYTHM SOCIETY SCIENTIFIC SESSIONS, 2015年11月, 英語, ASIA PCIFIC HEART RHYTHM SOCIETY, MELBOURNE, AUSTRALIA, 国際会議A novel mapping technique detecting the residual gap after wide circular pulmonary vein isolation口頭発表(一般)
- 8th ASIA PACIFIC HEART RHYTHM SOCIETY SCIENTIFIC SESSIONS, 2015年11月, 英語, ASIA PCIFIC HEART RHYTHM SOCIETY, MELBOURNE, AUSTRALIA, 国際会議ADVERSE EFFECTS ON PACING THRESHOLD OF CARDIAC PACEMAKER AFTER EXTERNAL CARDIOVERSIONポスター発表
- カテーテルアブレーション関連秋季大会2015, 2015年10月, 日本語, 日本不整脈学会, 福島, 国内会議右房-右肺静脈間の電気的伝導を証明し得た発作性心房細動の一例口頭発表(一般)
- カテーテルアブレーション関連秋季大会 2015, 2015年10月, 日本語, 日本不整脈学会, 福島, 国内会議Functional Pace-map Responseにより心外膜面に複数のVT回路を同定しアブレーションに成功した心筋炎後心筋症の1例口頭発表(一般)
- 第30回日本不整脈学会/第32回日本心電学会 合同学術集会, 2015年07月, 日本語, 日本不整脈学会/日本心電学会, 京都, 国内会議The effectiveness and the safety of epicardial radiofrequency catheter ablation for ventricular tachycardia refractory to endocardial catheter ablation口頭発表(一般)
- 第30回日本不整脈学会/第32回日本心電学会 合同学術集会, 2015年07月, 日本語, 日本不整脈学会/日本心電学会, 京都, 国内会議Stroke prevention and bleeding complications among warfarin,dabigatran,rivaroxaban and apixaban in patients undergoing AF ablation.口頭発表(一般)
- 第30回日本不整脈学会/第32回日本心電学会 合同学術集会, 2015年07月, 日本語, 日本不整脈学会/日本心電学会, 京都, 国内会議Relationship between J wave and ventricular fibrillation caused by coronary spastic angina口頭発表(一般)
- 第30回日本不整脈学会/第32回日本心電学会 合同学術集会, 2015年07月, 日本語, 日本不整脈学会/日本心電学会, 京都, 国内会議Radiofrequency Catheter Ablation for Electrical Storm of Ventricular Tachycardiain Structural Heart Diseaseシンポジウム・ワークショップパネル(公募)
■ 共同研究・競争的資金等の研究課題