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福島 健司医学部附属病院 肝胆膵外科講師
研究活動情報
■ 論文- OBJECTIVE: Centiloid (CL) scales play an important role in semiquantitative analyses of amyloid-β (Aβ) PET. CLs are derived from the standardized uptake value ratio (SUVR), which needs Aβ positron emission tomography (PET) normalization processing. There are two methods to collect the T1-weighted imaging (T1WI) for normalization: (i) anatomical standardization using simultaneously acquired T1WI (PET/MRI), usually adapted to PET images from PET/MRI scanners, and (ii) T1WI from a separate examination (PET + MRI), usually adapted to PET images from PET/CT scanners. This study aimed to elucidate the correlations and differences in CLs between when using the above two T1WI collection methods. METHODS: Among patients who underwent Aβ PET/MRI (using 11C-Pittuberg compound B (11C-PiB) or 18F-flutemetamol (18F-FMM)) at our institution from 2015 to 2023, we selected 49 patients who also underwent other additional MRI examinations, including T1WI for anatomic standardization within 3 years. Thirty-one of them underwent 11C-PiB PET/MRI, and 18 participants underwent 18F-FMM PET/MRI. Twenty-five of them, additional MRI acquisition parameters were identical to simultaneous MRI during PET, and 24 participants were different. After normalization using PET/MRI or PET + MRI method each, SUVR was measured using the Global Alzheimer's Association Initiative Network cerebral cortical and striatum Volume of Interest templates (VOI) and whole cerebellum VOI. Subsequently, CLs were calculated using the previously established equations for each Aβ PET tracer. RESULTS: Between PET/MRI and PET + MRI methods, CLs correlated linearly in 11C-PiB PET (y = 1.00x - 0.11, R2 = 0.999), 18F-FMM PET (y = 0.97x - 0.12, 0.997), identical additional MRI acquisition (y = 1.00x + 0.33, 0.999), different acquisition (y = 0.98x - 0.43, 0.997), and entire study group (y = 1.00x - 0.24, 0.999). Wilcoxon signed-rank test revealed no significant differences: 11C-PiB (p = 0.49), 18F-FMM (0.08), and whole PET (0.46). However, significant differences were identified in identical acquisition (p = 0.04) and different acquisition (p = 0.02). Bland-Altman analysis documented only a small bias between PET/MRI and PET + MRI in 11C-PiB PET, 18F-FMM PET, identical additional MRI acquisition, different acquisition, and whole PET (- 0.05, 0.67, - 0.30, 0.78, and 0.21, respectively). CONCLUSIONS: Anatomical standardizations using PET/MRI and using PET + MRI can lead to almost equivalent CL. The CL values obtained using PET/MRI or PET + MRI normalization methods are consistent and comparable in clinical studies.2024年10月, Annals of nuclear medicine, 38(10) (10), 835 - 846, 英語, 国内誌研究論文（学術雑誌）
- PURPOSE: The technical difficulties of laparoscopic liver resection (LLR) are greatly associated with the location of liver tumors. Since segment 8 (S8) contains a wide area, the difficulty of LLR for S8 tumors may vary depending on the location within the segment, such as the ventral (S8v) and dorsal (S8d) area, but the difference is unclear. METHODS: We retrospectively investigated 30 patients who underwent primary laparoscopic partial liver resection for liver tumors in S8 at Kobe University Hospital between January 2018 and June 2023. RESULTS: Thirteen and 17 patients underwent LLR for S8v and S8d, respectively. The operation time was significantly longer (S8v 203[135-259] vs. S8d 261[186-415] min, P = 0.002) and the amount of blood loss was significantly higher (10[10-150] vs. 10[10-200] mL, P = 0.034) in the S8d group than in the S8v group. No significant differences were observed in postoperative complications or postoperative length of hospital stay. Additionally, intraoperative findings revealed that the rate at which the case performed partial liver mobilization in the S8d group was higher (2[15.4%] vs. 8[47.1%], P = 0.060) and the median parenchymal transection time of the S8d group was longer (102[27-148] vs. 129[37-175] min, P = 0.097) than those in the S8v group, but there were no significant differences. CONCLUSION: The safety of LLR for the S8d was comparable to that of LLR for S8v, although LLR for S8d resulted in longer operative time and more blood loss. THE TRIAL REGISTRATION NUMBER: B230165 (approved at December 26, 2023).2024年08月, Langenbeck's archives of surgery, 409(1) (1), 243 - 243, 英語, 国際誌研究論文（学術雑誌）
- AIM: The IMbrave150 trial revealed that atezolizumab plus bevacizumab (AtezoBv) showed a higher objective response rate (ORR) in patients with advanced hepatocellular carcinoma (HCC). Although conversion therapy after AtezoBv has been recently reported, markers predictive of its efficacy, particularly radiological imaging markers, have not yet been identified. The present study focused on tumor morphological appearance on radiological imaging and evaluated whether it could be associated with AtezoBv efficacy. METHODS: Ninety-five intrahepatic lesions in 74 patients who were given AtezoBv for advanced HCC were recruited for evaluation. The lesions were divided into two groups, simple nodular (SN group) and non-simple nodular (non-SN group), based on the gross morphology on pretreatment imaging, and retrospectively evaluated for treatment response and other relevant clinical outcomes. RESULTS: Assessing the size of individual tumors after treatment, waterfall plots showed that tumor shrinkage in the non-SN group including 56 lesions was higher than that in the SN group comprising 39 lesions. The ORR was significantly higher in the non-SN group (39.3% vs. 15.4%, p = 0.012). Additionally, the median time to nodular progression was longer in the non-SN group (21.0 months vs. 8.1 months, p = 0.119) compared to the SN group. Six patients with non-SN lesions underwent sequential local therapy. CONCLUSIONS: Atezolizumab plus bevacizumab may show increased therapeutic efficacy in patients with tumors with a higher potential for aggressive oncological behavior, such as non-SN lesions. Treatment strategies focusing on conversion therapy may be crucial in patients with non-SN lesions.2024年08月, Hepatology research : the official journal of the Japan Society of Hepatology, 54(8) (8), 773 - 780, 英語, 国際誌研究論文（学術雑誌）
- PURPOSE: The impact of postoperative bile leak on the prognosis of patients with hepatocellular carcinoma who underwent liver resection is controversial. This study aimed to investigate the prognostic impact of bile leak for patients with hepatocellular carcinoma who underwent liver resection. METHODS: Patients with hepatocellular carcinoma who underwent liver resection between 2009 and 2019 at Kobe University Hospital and Hyogo Cancer Center were included. After propensity score matching between the bile leak and no bile leak groups, differences in 5-year recurrence-free and overall survival rates were evaluated using the Kaplan-Meier method. RESULTS: A total of 781 patients, including 43 with postoperative bile leak, were analyzed. In the matched cohort, 40 patients were included in each group. The 5-year recurrence-free survival rates after liver resection were 35% and 32% for the bile leak and no bile leak groups, respectively (P = 0.857). The 5-year overall survival rates were 44% and 54% for the bile leak and no bile leak groups, respectively (P = 0.216). CONCLUSION: Overall, bile leak may not have a profound negative impact on the prognosis of patients with hepatocellular carcinoma who have undergone liver resection.2024年07月, Langenbeck's archives of surgery, 409(1) (1), 233 - 233, 英語, 国際誌研究論文（学術雑誌）
- OBJECTIVE: We aimed to elucidate the factors underlying the difference between estimated glomerular filtration rate (eGFR) calculated from serum creatinine and Gate's GFR (gGFR) measured using technetium-99m diethylene triamine pentaacetic acid ( 99m Tc-DTPA) scintigraphy. METHODS: This study was based on consecutive patients who underwent 99m Tc-DTPA scintigraphy at our hospital between January 2021 and December 2022 and whose blood serum creatinine data were obtained on the same day as the 99m Tc-DTPA scintigraphy. Relationships between the ratio of gGFR and eGFR (gGFR/eGFR) and age, sex, BMI, visceral fat, psoas muscle index (PMI), serum blood urea nitrogen, and creatinine level were investigated based on 75 patients. Additionally, for 44 patients who had two or more follow-up DTPA studies, we compared gGFR values for studies that used iodine contrast media (ICM) for computed tomography before same-day 99m Tc-DTPA studies and those that did not in the same patients. RESULTS: Weak correlations were observed between gGFR/eGFR and PMI ( r = 0.30), BMI ( r = 0.24), and the visceral fat area ( r = 0.33). Multi-regression analyses showed that gGFR/eGFR was correlated with PMI ( β = 0.34, P < 0.01) and approached significance with the visceral fat area ( β = 0.24, P = 0.05). A significant difference was observed in gGFR between patients who received ICM before the 99m Tc-DTPA renogram and those who did not ( P < 0.001, eGFR 80.5 ± 19.0 vs. 91.7 ± 27.8 ml/min). CONCLUSION: ICM administration temporarily decreased gGFR, and increased muscle mass increased the difference between eGFR and gGFR values.2024年07月, Nuclear medicine communications, 45(7) (7), 573 - 580, 英語, 国際誌研究論文（学術雑誌）
- Tremelimumab plus durvalumab (Dur/Tre) is the first-line treatment for advanced hepatocellular carcinoma (HCC) worldwide. The present report describes the case of a 68-year-old man diagnosed with advanced HCC and a bile duct tumor thrombus (BDTT) who achieved a complete response to Dur/Tre therapy. The BDTT progressed to the bifurcation of the left and right hepatic ducts. Over time, both the tumors and BDTT progressively decreased in size, and a complete response was confirmed using the Response Evaluation Criteria in Solid Tumors (version 1.1.) 6 months after treatment administration. Subsequently, immune-related adverse events, including type 1 diabetes mellitus and diabetic ketoacidosis, emerged, leading to treatment discontinuation. The patient was undergoing outpatient follow-up in a drug-free state with no signs of recurrence 290 days after the initial administration of Dur/Tre. Although long-term and meticulous observations are required, the present findings could influence the choice of systemic chemotherapy for advanced HCC.2024年07月, Oncology letters, 28(1) (1), 332 - 332, 英語, 国際誌
- INTRODUCTION: Surgical resection is considered an effective cure for biliary tract cancer (BTC); however, the prognosis is unsatisfactory despite improved surgical techniques and perioperative management. The recurrence rate remains high even after curative resection. The efficacy of adjuvant chemotherapy in pancreatic and gastric cancers has been previously reported, and the feasibility of adjuvant therapy with S-1 has recently been reported in patients with resected BTC. We aimed to retrospectively investigate the effects of adjuvant chemotherapy with S-1 on resected advanced BTC. METHODS: We included data from 438 BTC patients who underwent resection between 2001 and 2020. After excluding patients with pTis-pT1 (n = 112) and other exclusion criteria, 266 patients were included in the analysis. RESULTS: After propensity score matching, 48 patients received S-1 adjuvant chemotherapy (S-1 group), and 48 patients received non-S1 adjuvant chemotherapy or underwent surgery alone (Non-S-1 group). The patients in the S-1 group had significantly better overall survival (OS) than those in the non-S-1 group (MST 51 vs 37 months, hazard ratio [HR]:.54, 95% confidence interval [CI]:.30-.98, P = .04). The S-1 group had a significantly better recurrence-free survival (RFS) than the non-S-1 group (94 vs 21 months, HR: .57, 95% CI: .33-.97, P = .03). Subgroup analyses for OS and RFS exhibited the benefits of S-1 in patients aged <75 years and in patients with primary sites of extrahepatic and perineural invasion and curability of R0. DISCUSSION: S-1 adjuvant therapy is promising for improving the postoperative survival of patients with resected advanced BTC, positive nerve invasion, and R0 resection.2024年06月, The American surgeon, 90(6) (6), 1279 - 1289, 英語, 国際誌研究論文（学術雑誌）
- Spontaneous rupture of a primary hepatocellular carcinoma (HCC) is a frequently observed and fatal complication. However, the rupture of lymph node (LN) metastases from HCC is rare. A 79 year-old male with hepatitis B underwent three liver resections for HCC. Two years and 6 months after the last liver resection, enhanced computed tomography (CT) revealed a nodule with a diameter of 3 cm in the lower pole of the spleen. Splenic metastasis of HCC was suspected, and splenectomy was scheduled. During our hospital stay for a urinary tract infection before the scheduled operation, he complained of acute left-sided abdominal pain, and CT showed intra-abdominal hemorrhage due to rupture of the splenic tumor. Emergency splenectomy was performed, and the postoperative course was uneventful. Histopathological examination revealed a poorly differentiated HCC in the lower splenic pole lesion, which contained LN structures. The ruptured lesion was diagnosed as splenic hilar LN metastasis of HCC. Although laparoscopic partial liver resection was performed for intrahepatic recurrence, and atezolizumab plus bevacizumab therapy was administered for peritoneal metastases, the patient was alive 25 months after the splenectomy. Our case suggests that emergency surgery for LN metastatic rupture can achieve hemostasis and lead to improved survival outcomes.2024年06月, Clinical journal of gastroenterology, 17(3) (3), 557 - 562, 英語, 国内誌研究論文（学術雑誌）
- Purpose To investigate whether right ventricular (RV) myocardial strain ratio (RVMSR) assessed using nitrogen 13 ammonia (13N-NH3) PET can predict cardiovascular events in patients with ischemic heart disease (IHD). Materials and Methods This retrospective study included 480 consecutive patients (mean age, 66 years ± 12 [SD]; 334 males and 146 females) with IHD who underwent 13N-NH3 PET. RVMSR was defined as the ratio of RV strain during stress to that at rest. The primary end point was major adverse cardiac events (MACEs), defined as cardiac death or heart failure hospitalization. The ability of RVMSR to predict MACE was assessed using receiver operating characteristic (ROC) curve and Kaplan-Meier analyses. Cox proportional hazards regression analysis was used to calculate hazard ratios (HRs) with 95% CIs. Results ROC curve analysis identified a sensitivity and specificity of 84% and 82%, respectively, for predicting MACE from RVMSR. Patients with reduced RVMSR (<110.2) displayed a significantly higher rate of MACE than those with a preserved RVMSR (34 of 240 vs four of 240; P < .001). Cox proportional hazards regression analysis of imaging parameters, including myocardial flow reserve, indicated that RVMSR was an independent predictor of MACE (HR, 0.94 [95% CI: 0.92, 0.97]; P < .001). Conclusion RVMSR was an independent predictor of MACE and has potential to aid in the risk stratification of patients with IHD. Keywords: Right Ventricular Myocardial Strain Ratio, Myocardial Flow Reserve, Ischemic Heart Disease, 13N-Ammonia Positron Emission Tomography Supplemental material is available for this article. © RSNA, 2024.2024年06月, Radiology. Cardiothoracic imaging, 6(3) (3), e230298, 英語, 国際誌研究論文（学術雑誌）
- We aimed to evaluate the prognostic value of left ventricular global longitudinal strain (LVGLS) and left atrial strain (LAS) obtained from magnetic resonance imaging (MRI) feature tracking in patients with heart failure with preserved ejection fraction (HFpEF). We retrospectively enrolled consecutive patients with HFpEF admitted to our hospital who underwent cardiac MRI. LVGLS and LAS were obtained from cine MRI by feature tracking. The end point was defined as a composite of all-cause death, myocardial infarction, and hospitalization due to decompensated HF. One-hundred patients with HFpEF were enrolled. Mean LVGLS and LAS were - 13.7 ± 3.7% and 22.5 ± 11.6%, respectively. During follow-up of 4.4 ± 1.9 years, 24 events occurred. Multivariate Cox proportional hazards model analysis demonstrated LAS was independently associated with adverse cardiac events. Kaplan-Meier curve analysis revealed that the patients with both LVGLS and LAS worse than the median (LVGLS ≥ - 12.2% and LAS ≤ 13.8%) had a significantly lower event-free rate compared to those with preserved strain (Log-rank P < 0.001). Simultaneous assessment of LVGLS and LAS using MRI was useful for risk stratification in the patients with HFpEF.2024年05月, Heart and vessels, 39(5) (5), 404 - 411, 英語, 国内誌研究論文（学術雑誌）
- BACKGROUND: Drainage fluid amylase (DFA) is useful for predicting clinically relevant postoperative pancreatic fistula (CR-POPF) after distal pancreatectomy (DP). However, difference in optimal cutoff value of DFA for predicting CR-POPF between open DP (ODP) and laparoscopic DP (LDP) has not been investigated. This study aimed to identify the optimal cutoff values of DFA for predicting CR-POPF after ODP and LDP. METHODS: Data for 294 patients (ODP, n = 127; LDP, n = 167) undergoing DP at Kobe University Hospital between 2010 and 2021 were reviewed. Propensity score matching was performed to minimize treatment selection bias. Receiver operating characteristic (ROC) analysis was performed to determine the optimal cutoff values of DFA for predicting CR-POPF for ODP and LDP. Logistic regression analysis for CR-POPF was performed to investigate the diagnostic value of DFA on postoperative day (POD) three with identified cutoff value. RESULTS: In the matched cohort, CR-POPF rates were 24.7% and 7.9% after ODP and LDP, respectively. DFA on POD one was significantly lower after ODP than after LDP (2263 U/L vs 4243 U/L, p < 0.001), while the difference was not significant on POD three (543 U/L vs 1221 U/L, p = 0.171). ROC analysis revealed that the optimal cutoff value of DFA on POD one and three for predicting CR-POPF were different between ODP and LDP (ODP, 3697 U/L on POD one, 1114 U/L on POD three; LDP, 10564 U/L on POD one, 6020 U/L on POD three). Multivariate analysis showed that DFA on POD three with identified cutoff value was the independent predictor for CR-POPF both for ODP and LDP. CONCLUSIONS: DFA on POD three is an independent predictor for CR-POPF after both ODP and LDP. However, the optimal cutoff value for it is significantly higher after LDP than after ODP. Optimal threshold of DFA for drain removal may be different between ODP and LDP.2024年05月, Surgical endoscopy, 38(5) (5), 2699 - 2708, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND/AIM: The treatment algorithm for systemic therapies for advanced hepatocellular carcinoma (HCC) has changed dramatically; however, the therapeutic landscape for sequential second-line or later-line treatments, including ramucirumab, remains controversial. This study aimed to investigate the role of ramucirumab for treating HCC. PATIENTS AND METHODS: We retrospectively analyzed data from 17 patients with advanced HCC who received ramucirumab, and 8 of them who received lenvatinib re-administration after ramucirumab treatment failure. RESULTS: The median overall survival of 17 patients treated with ramucirumab was 11.5 months. The median ratios of the 1-month post-treatment α-fetoprotein (AFP) levels and albumin-bilirubin (ALBI) scores to the pre-treatment AFP levels and ALBI scores following ramucirumab treatment were 0.880 and 0.965, respectively. The median ratios of the 1-month post-treatment AFP and ALBI levels to the pre-treatment levels were 1.587 and 0.970 for mALBI grade 1/2a, and 1.313 and 0.936 for mALBI grade 2b/3, respectively. Six of the eight patients who received lenvatinib rechallenge treatment exhibited a decrease in AFP levels one month post-lenvatinib treatment. Deterioration of liver function 3 months post-lenvatinib treatment was noted in five of the eight patients who received lenvatinib rechallenge treatment after ramucirumab. CONCLUSION: Ramucirumab may be equally useful in patients with unresectable HCC who have poor liver function or whose liver function is aggravated by other therapies. Rechallenge treatment with lenvatinib after ramucirumab may be a valid treatment option for HCC.2024年05月, Anticancer research, 44(5) (5), 2055 - 2061, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND/AIM: This study aimed to evaluate the utility of the albumin-bilirubin grade for predicting the prognosis after repeat liver resection for patients with recurrent hepatocellular carcinoma. PATIENTS AND METHODS: Ninety patients with intrahepatic recurrent hepatocellular carcinoma who underwent repeat liver resection at our institution between 2005 and 2019 were retrospectively analyzed. Cox proportional-hazards regression models evaluated independent preoperative prognostic factors, including the albumin-bilirubin grade. Prognosis differences between patients with albumin-bilirubin grades 1 and 2 were analyzed using the Kaplan-Meier method. RESULTS: Cox proportional-hazards regression analysis revealed that albumin-bilirubin grade 2 (p=0.003) and early recurrence within one year from the initial surgery (p=0.001) were independently associated with poor recurrence-free survival, and albumin-bilirubin grade 2 (p=0.020) was independently associated with poor overall survival. The five-year recurrence-free (31% and 17%, respectively) and overall (86% and 60%, respectively) survival rates after repeat liver resection for patients with albumin-bilirubin grades 1 and 2 were significantly different between groups (both p=0.003). CONCLUSION: The albumin-bilirubin grade is useful for preoperatively predicting favorable survival rates after repeat liver resection for patients with recurrent hepatocellular carcinoma. Patients with an albumin-bilirubin grade 1 are better candidates for surgical treatment of recurrent hepatocellular carcinoma.2024年05月, Anticancer research, 44(5) (5), 2031 - 2038, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND: Pulmonary hypertension leads to right ventricular failure, which is a major determinant of prognosis. Circulating biomarkers for right ventricular function are poorly explored in pulmonary hypertension. This study aimed to clarify the significance of collagen triple helix repeat-containing protein 1 (CTHRC1) as a biomarker of right ventricular failure in pulmonary hypertension. METHODS: A monocrotaline-induced pulmonary hypertension rat model was used to evaluate right ventricular CTHRC1 expression and its relationship with fibrosis. Next, human plasma CTHRC1 levels were measured in controls (n = 20), pulmonary arterial hypertension (n = 46), and patients with chronic thromboembolic pulmonary hypertension (CTEPH) (n = 64) before the first and after the final balloon pulmonary angioplasty. RESULTS: CTHRC1 expression was higher in the right ventricles of rats with monocrotaline-induced pulmonary hypertension than in those of controls. CTHRC1 was colocalized with vimentin and associated with fibrosis in the right ventricles. Plasma CTHRC1 levels were higher in human patients with pulmonary arterial hypertension (P = 0.006) and CTEPH (P = 0.011) than in controls. Plasma CTHRC levels were correlated with B-type natriuretic peptide (R = 0.355, P < 0.001), tricuspid lateral annular peak systolic velocity (R = -0.213, P = 0.029), and right ventricular fractional area change (R = -0.225, P = 0.017). Finally, plasma CTHRC1 levels were decreased after the final balloon pulmonary angioplasty (P < 0.001) in CTEPH. CONCLUSIONS: CTHRC1 can be a circulating biomarker associated with right ventricular function and fibrosis in pulmonary hypertension and might reflect the therapeutic efficacy of balloon pulmonary angioplasty in CTEPH.2024年04月, The Canadian journal of cardiology, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND: Venous thromboembolism (VTE) is a potentially fatal complication of hepatectomy. The use of postoperative prophylactic anticoagulation in patients who have undergone hepatectomy is controversial because of the risk of postoperative bleeding. Therefore, we hypothesized that monitoring plasma D-dimer could be useful in the early diagnosis of VTE after hepatectomy. AIM: To evaluate the utility of monitoring plasma D-dimer levels in the early diagnosis of VTE after hepatectomy. METHODS: The medical records of patients who underwent hepatectomy at our institution between January 2017 and December 2020 were retrospectively analyzed. Patients were divided into two groups according to whether or not they developed VTE after hepatectomy, as diagnosed by contrast-enhanced computed tomography and/or ultrasonography of the lower extremities. Clinicopathological factors, including demographic data and perioperative D-dimer values, were compared between the two groups. Receiver operating characteristic curve analysis was performed to determine the D-dimer cutoff value. Univariate and multivariate analyses were performed using logistic regression analysis to identify significant predictors. RESULTS: In total, 234 patients who underwent hepatectomy were, of whom (5.6%) were diagnosed with VTE following hepatectomy. A comparison between the two groups showed significant differences in operative time (529 vs 403 min, P = 0.0274) and blood loss (530 vs 138 mL, P = 0.0067). The D-dimer levels on postoperative days (POD) 1, 3, 5, 7 were significantly higher in the VTE group than in the non-VTE group. In the multivariate analysis, intraoperative blood loss of > 275 mL [odds ratio (OR) = 5.32, 95% confidence interval (CI): 1.05-27.0, P = 0.044] and plasma D-dimer levels on POD 5 ≥ 21 μg/mL (OR = 10.1, 95%CI: 2.04-50.1, P = 0.0046) were independent risk factors for VTE after hepatectomy. CONCLUSION: Monitoring of plasma D-dimer levels after hepatectomy is useful for early diagnosis of VTE and may avoid routine prophylactic anticoagulation in the postoperative period.2024年01月, World journal of clinical cases, 12(2) (2), 276 - 284, 英語, 国際誌研究論文（学術雑誌）
- INTRODUCTION: The usefulness of gadolinium-ethoxybenzyl diethylenetriamine pentaacetate acid-enhanced magnetic resonance imaging (EOB-MRI) in assessing the functional future remnant liver volume (fFRLV) to predict post-hepatectomy liver failure (PHLF) has been previously reported. Herein, we evaluated the efficacy of this technique in patients with hepatocellular carcinoma (HCC) with a major portal vein tumor thrombus (PVTT). METHODS: This study included 21 patients with PVTT in the ipsilateral first-order branch (Vp3) and 30 patients with PVTT in the main trunk/contralateral branch (Vp4). To evaluate fFRLV, the signal intensity (SI) of the remnant liver was determined on T1-weighted images, using both conventional and newly developed methods. The fFRLV was calculated using the SI of the remnant liver and muscle, remnant liver volume, and body surface area. Preoperative factors predicting PHLF (≥grade B) in HCC patients with Vp3/4 PVTT were evaluated. RESULTS: In the Vp3 group, we found fFRLV area under the receiver-operating characteristic curves (AUCs) above 0.70 (AUC = 0.875, 0.750) using EOB-MRI results calculated using either the plot or whole method. None of the parameters in the Vp4 group had an AUC greater than 0.70. CONCLUSION: The fFRLV calculated by EOB-MRI using the whole method can be as useful as the conventional method in predicting PHLF (≥grade B) for HCC patients with Vp3 PVTT.2024年, Digestive surgery, 41(1) (1), 30 - 36, 英語, 国際誌研究論文（学術雑誌）
- Paravalvular leakage (PVL) is a complication of transcatheter aortic valve implantation (TAVI) for aortic stenosis, leading to an adverse prognosis. We investigated whether aortic valve calcium volume (Ca-Vol) measured by preoperative cardiac computed tomography had a predictive value for PVL after TAVI using a third-generation self-expandable valve.We retrospectively analyzed 59 consecutive patients who underwent TAVI using a third-generation self-expandable valve. We measured Ca-Vol in the aortic valve and each cusp (non-coronary cusp [NCC], right-coronary cusp [RCC], and left-coronary cusp [LCC]). We divided the patients into 2 groups: a PVL group (32.2%) and a non-PVL group (67.8%). Total Ca-Vol was significantly higher in the PVL group than in the non-PVL group (P < 0.001). Ca-Vol in each cusp was also significantly higher in the PVL group ([NCC] P < 0.001, [RCC] P = 0.001, [LCC] P < 0.001). Univariate logistic regression analysis for PVL indicated that the total and per-cusp Ca-Vols were predictors for PVL (total, odds ratio [OR] 4.0, P < 0.001; NCC, OR 12.5, P = 0.002; RCC, OR 16.0, P = 0.008; LCC, OR 44.5, P < 0.001).Receiver operating characteristic curve analysis of Ca-Vol for predicting PVL revealed the optimal cut-off values of Ca-Vol were 2.4 cm3 for the total, 0.74 cm3 for NCC, 0.73 cm3 for RCC, and 0.56 cm3 for LCC (area under the curve, 0.85, 0.79, 0.76, and 0.83, respectively).Preoperative total, NCC, RCC, and LCC calcium volumes were significant predictors for PVL after TAVI using third-generation self-expandable valves.2024年, International heart journal, 65(1) (1), 63 - 70, 英語, 国内誌研究論文（学術雑誌）
- Investigation of factors affecting CT attenuation and glucose metabolism of bone marrow as seen on PET/CT scans.The aim of this study is to determine the factors affecting the CT attenuation of bone marrow, and its correlation with 18F-FDG uptake. The mean standardized uptake value (SUV) of vertebral bone marrow (Vertebral-SUV) and femoral bone marrow (Femoral-SUV) as well as CT number of bone marrow (BM-CT number) were measured in 243 patients who had undergone 18F-FDG PET/CT. The correlations among BM-CT number, Femoral-SUV, and Vertebral-SUV were investigated. The relationships of Femoral-SUV, Vertebral-SUV, and BM-CT number with blood parameters, age, blood sugar, and body weight were analyzed by correlation and multi-regression analyses. The Mann-Whitney U test and chi-square test and Binomial logistic analysis were used to examine the relationships between high BM-CT number (≥ 0 HU) and the above parameters. Significant correlations were observed between: BM-CT number and Femoral-SUV (r = 0.73, P < 0.01); Vertebral-SUV and Femoral-SUV (r = 0.78, P < 0.01); and BM-CT number and Vertebral-SUV (r = 0.52, P < 0.01). BM-CT number was correlated with patients' age in both univariable (r = -0.27) and multivariable analyses (β = -0.20). Positive BM-CT number correlated with WBC in both univariable (P = 0.04) and multivariable (P < 0.01) analyses. Bone marrow glucose metabolism had a tendency to decrease with age, was increased in patients with elevated CRP. In conclusion, CT attenuation of bone marrow correlated well with bone marrow metabolism and also tended to decrease with age. High bone marrow attenuation (≥ 0 HU) could predict elevated serum WBC.2024年, American journal of nuclear medicine and molecular imaging, 14(1) (1), 22 - 30, 英語, 国際誌研究論文（学術雑誌）
- Surgical resection is recommended for advanced-stage, resectable glottic cancer. However, total laryngectomy results in the loss of vocal function and reduces patients' quality of life. At our institution, patients with cT3N0M0 stage III resectable glottic cancer who wish to preserve their larynx are treated with super-selective cisplatin infusion with concomitant radiotherapy (RADPLAT) to improve local control over systemic chemotherapy. Herein, we present 4 patients with glottic cancer who underwent biweekly intra-arterial infusion chemotherapy combined with radiation therapy 3 times. For intra-arterial infusion chemotherapy, 100 mg cis-diaminodichloroplatinum was infused into the superior thyroid artery, including the superior laryngeal artery branch. Thereafter, intensity-modulated radiation therapy was administered at doses of 70 Gy in 35 fractions for 3 patients and 66 Gy in 33 fractions for 1 patient. These patients showed complete response after chemoradiotherapy with no recurrence or metastases during the follow-up period to date (mean follow-up period: 56 months, range: 39-76 months).2023年12月, Radiology case reports, 18(12) (12), 4514 - 4521, 英語, 国際誌
- Subgenome dominance after whole-genome duplication generates distinction in gene number and expression at the level of chromosome sets, but it remains unclear how this process may be involved in evolutionary novelty. Here we generated a chromosome-scale genome assembly of the Asian pitcher plant Nepenthes gracilis to analyse how its novel traits (dioecy and carnivorous pitcher leaves) are linked to genomic evolution. We found a decaploid karyotype and a clear indication of subgenome dominance. A male-linked and pericentromerically located region on the putative sex chromosome was identified in a recessive subgenome and was found to harbour three transcription factors involved in flower and pollen development, including a likely neofunctionalized LEAFY duplicate. Transcriptomic and syntenic analyses of carnivory-related genes suggested that the paleopolyploidization events seeded genes that subsequently formed tandem clusters in recessive subgenomes with specific expression in the digestive zone of the pitcher, where specialized cells digest prey and absorb derived nutrients. A genome-scale analysis suggested that subgenome dominance likely contributed to evolutionary innovation by permitting recessive subgenomes to diversify functions of novel tissue-specific duplicates. Our results provide insight into how polyploidy can give rise to novel traits in divergent and successful high-ploidy lineages.2023年12月, Nature plants, 9(12) (12), 2000 - 2015, 英語, 国際誌研究論文（学術雑誌）
- A recent study employs computational models to explore the functional morphology of carnivorous trapping pitchers in Nepenthes. Focusing on the peristome, the study uncovers new dimensions in form-function relationships, offering theoretical insights into the role of complex trap morphology.2023年11月, Current biology : CB, 33(21) (21), R1155-R1157, 英語, 国際誌研究論文（学術雑誌）
- The regional differences in cerebral oxygen extraction fraction (OEF) in brain were investigated using positron emission tomography (PET) in detail with consideration of systemic errors in PET measurement estimated by simulation studies. The cerebral blood flow (CBF), cerebral blood volume (CBV), OEF, and cerebral metabolic rate of oxygen (CMRO2) were measured on healthy men by PET with 15O-labeled gases. The OEF values in the pons and the parahippocampal gyrus were significantly smaller than in the other brain regions. The OEF value in the lateral side of the occipital cortex was largest among the cerebral cortical regions. Simulation studies have revealed that errors in OEF caused by regional differences in the distribution volume of 15O-labeled water, as well as errors in OEF caused by a mixture of gray and white matter, must be negligible. The regional differences in OEF in brain must exist which might be related to physiological meanings.Article title: Kindly check and confirm the edit made in the article title.I have checked the article title and it is OK as is. Trial registration: The UMIN clinical trial number: UMIN000033382, https://www.umin.ac.jp/ctr/index.htm.2023年10月, The journal of physiological sciences : JPS, 73(1) (1), 25 - 25, 英語, 国内誌研究論文（学術雑誌）
- Noninvasive cardiovascular imaging plays a key role in diagnosis and patient management including monitoring treatment efficacy. The usefulness of noninvasive cardiovascular imaging has been extensively studied and shown to have high diagnostic reliability and prognostic significance, while the nondiagnostic results frequently encountered with single imaging modality require complementary or alternative imaging techniques. Hybrid cardiac imaging was initially introduced to integrate anatomical and functional information to enhance the diagnostic performance, and lately employed as a strategy for comprehensive assessment of the underlying pathophysiology of diseases. More recently, the utility of computed tomography has grown in diversity, and emerged from being an exploratory technique allowing functional measurement such as stress dynamic perfusion. Cardiac magnetic resonance imaging (CMR) is widely accepted as a robust tool for evaluation of cardiac function, fibrosis, and edema, yielding high spatial resolution and soft-tissue contrast. However, the use of intravenous contrast materials is typically required for accurate diagnosis with these imaging modalities, despite the associated risk of renal toxicity. Nuclear cardiology, established as a molecular imaging technique, has advantages in visualization of the disease-specific biological process at cellular level using numerous probes without requiring contrast materials. Various imaging modalities should be appropriately used sequentially to assess concomitant disease and the progression over time. Therefore, simultaneous evaluation combining high spatial resolution and disease-specific imaging probe is a useful approach to identify the regional activity and the stage of the disease. Given the recent advance and potential of multiparametric CMR and novel nuclide tracers, hybrid positron emission tomography MR is becoming an ideal tool for disease-specific imaging.2023年10月, Journal of cardiology, 82(4) (4), 286 - 292, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND: Postoperative cholangitis is a common complication of pancreaticoduodenectomy. Frequent cholangitis impairs patients' quality of life after pancreaticoduodenectomy. However, the risk factors for recurrence of cholangitis remain unclear. Hence, this retrospective study aimed to identify risk factors for recurrence of cholangitis after pancreaticoduodenectomy. METHODS: The medical records of patients who underwent pancreaticoduodenectomy between 2015 and 2019 in our institution were retrospectively reviewed. At least two episodes of cholangitis a year after pancreaticoduodenectomy were defined as 'recurrence of cholangitis' in the present study. Univariate and multivariate analyses were performed. RESULTS: The recurrence of cholangitis occurred in 40 of 207 patients (19.3%). Multivariate analysis revealed that internal stent (external, RR: 2.16, P = 0.026; none, RR: 4.76, P = 0.011), firm pancreas (RR: 2.61, P = 0.021), constipation (RR: 3.49, P = 0.008), and postoperative total bilirubin>1.7 mg/dL (RR: 2.94, P = 0.006) were risk factors of recurrence of cholangitis. Among patients with internal stents (n = 54), those with remnant stents beyond 5 months had more frequent recurrence of cholangitis (≥5 months, 75%; <5 months, 30%). CONCLUSIONS: Internal stents, firm pancreas, constipation, and postoperative high bilirubin levels are risk factors for cholangitis recurrence after pancreaticoduodenectomy. In addition, the long-term implantation of internal stents may trigger cholangitis recurrence.2023年10月, World journal of surgery, 47(10) (10), 2499 - 2506, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND: Advances in cancer treatment have resulted in increased attention toward potential cardiac complications, especially following treatment for esophageal cancer, which is associated with a risk of coronary artery disease. As the heart is directly irradiated during radiotherapy, coronary artery calcification (CAC) may progress in the short term. Therefore, we aimed to investigate the characteristics of patients with esophageal cancer that predispose them to coronary artery disease, CAC progression on PET-computed tomography and the associated factors, and the impact of CAC progression on clinical outcomes. METHODS: We retrospectively screened 517 consecutive patients who received radiation therapy for esophageal cancer from our institutional cancer treatment database between May 2007 and August 2019. CAC scores were analyzed clinically for 187 patients who remained by exclusion criteria. RESULTS: A significant increase in the Agatston score was observed in all patients (1 year: P = 0.001*, 2 years: P < 0.001*). Specifically for patients receiving middle-lower chest irradiation (1 year: P = 0.001*, 2 years: P < 0.001*) and those with CAC at baseline (1 year: P = 0.001*, 2 years: P < 0.001*), a significant increase in the Agatston score was observed. There was a trend for a difference in all-cause mortality between patients who had irradiation of the middle-lower chest ( P = 0.053) and those who did not. CONCLUSION: CAC can progress within 2 years after the initiation of radiotherapy to the middle or lower chest for esophageal cancer, particularly in patients with detectable CAC before radiotherapy initiation.2023年09月, Coronary artery disease, 34(6) (6), 453 - 461, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND: Previous studies have shown that the Valsalva maneuver (VM) causes spinal canal object movements. We hypothesized that this occurs because of cerebrospinal fluid (CSF) flow generated from intradural space reduction. Previous studies using myelograms reported lumbar CSF space changes during inspiration. However, no similar studies have been conducted using modern MRI. Therefore, this study analyzed intradural space reduction during the VM using cine magnetic resonance imaging (MRI). METHODS: The participant was a 39-year-old, healthy, male volunteer. Cine MRI involved fast imaging employing steady-state acquisition cine sequence during three resting and VM sets for 60 s each. The axial plane was at the intervertebral disc and vertebral body levels between Th12 and S1 during cine MRI. This examination was performed on 3 separate days; hence, data from nine resting and VM sets were available. Additionally, two-dimensional myelography was performed during rest and the VM. RESULTS: Intradural space reduction was observed during the VM using cine MRI and myelography. The intradural space cross-sectional area during the VM (mean: 129.3 mm2; standard deviation [SD]: 27.4 mm2) was significantly lower than that during the resting period (mean: 169.8; SD: 24.8; Wilcoxon signed-rank test, P < 0.001). The reduction rate of the vertebral body level (mean: 26.7%; SD: 9.4%) was larger than that of the disc level (mean: 21.4%; SD: 9.5%; Wilcoxon rank sum test, P = 0.0014). Furthermore, the reduction was mainly observed on the ventral and bilateral intervertebral foramina sides at the vertebral body and intervertebral disc levels, respectively. CONCLUSION: The intradural space was reduced during the VM, possibly because of venous dilatation. This phenomenon may be associated with CSF flow, intradural object movement, and nerve compression, potentially leading to back pain.2023年08月, Acta neurochirurgica, 165(8) (8), 2111 - 2120, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND: Few reports have discussed the association between total tumor volume (TTV) and prognosis in patients with colorectal liver metastases (CRLM). The present study aimed to evaluate the usefulness of TTV for predicting recurrence-free survival and overall survival (OS) in patients receiving initial hepatic resection or chemotherapy, and to investigate the value of TTV as an indicator for optimal treatment selection for patients with CRLM. PATIENTS AND METHODS: This retrospective cohort study included patients with CRLM who underwent hepatic resection (n = 93) or chemotherapy (n = 78) at the Kobe University Hospital. TTV was measured using 3D construction software and computed tomography images. RESULTS: A TTV of 100 cm3 has been previously reported as a significant cut-off value for predicting OS of CRLM patients receiving initial hepatic resection. For patients receiving hepatic resection, the OS for those with a TTV ≥ 100 cm3 was significantly reduced compared with those with a TTV < 100 cm3. For patients receiving initial chemotherapy, there were no significant differences between the groups divided according to TTV cut-offs. Regarding OS of patients with TTV ≥ 100 cm3, there was no significant difference between hepatic resection and chemotherapy (p = 0.160). CONCLUSIONS: TTV can be a predictive factor of OS for hepatic resection, unlike for initial chemotherapy treatment. The lack of significant difference in OS for CRLM patients with TTV ≥ 100 cm3, regardless of initial treatment, suggests that chemotherapeutic intervention preceding hepatic resection may be indicated for such patients.2023年06月, Annals of surgical oncology, 30(11) (11), 6603 - 6610, 英語, 国際誌研究論文（学術雑誌）
- Transarterial chemoembolization (TACE) is performed for pancreatic neuroendocrine tumor (PanNEN) liver metastases; however, the safety and efficacy of TACE procedures, especially for patients who have undergone previous pancreatic surgery, have not been established. We reviewed 48 TACE procedures (1-6 procedures/patient) performed on 11 patients with PanNEN liver metastases, including 16 TACE procedures (4-6 procedures/patient) for 3 patients with a history of biliary-enteric anastomosis. The overall tumor objective response rate was 94%. The incidence of Clavien‒Dindo grade ≥ 2 complications was 1/16 (6%) and 1/32 (3%), and the median time to untreatable progression was 31 (14-41) and 27 (2-60) months among patients with and without a history of biliary-enteric anastomosis, respectively. Although validation is needed in future studies, our experiences have shown that TACE treatment is a viable treatment option for PanNEN liver metastases, even after biliary-enteric anastomosis with experienced teams and careful patient follow-up.2023年06月, Surgery today, 53(12) (12), 1396 - 1400, 英語, 国内誌研究論文（学術雑誌）
- BACKGROUND: Less intra-abdominal adhesions are expected following laparoscopic surgery. Although an initial laparoscopic approach for primary liver tumors may have advantages in patients who require repeat hepatectomies for recurrent liver tumors, this has not been sufficiently investigated. METHODS: Patients who underwent repeat hepatectomies for recurrent liver tumors at our hospital between 2010 and 2022 were retrospectively analyzed. Of 127 patients, 76 underwent laparoscopic repeat hepatectomy (LRH), of whom 34 patients initially underwent laparoscopic hepatectomy (L-LRH) and 42, open hepatectomy (O-LRH). Fifty-one patients underwent open hepatectomy as both the initial and second operation (O-ORH). We analyzed surgical outcomes between L-LRH and O-LRH groups and between L-LRH and O-ORH groups using propensity-matching analysis for each pattern. RESULTS: Twenty-one patients each were included in L-LRH and O-LRH propensity-matched cohorts. The L-LRH group had a lower rate of postoperative complications than the O-LRH group (0 vs 19%, P = 0.036). When we compared surgical outcomes between L-LRH and O-ORH groups in another matched cohort with 18 patients in each group, in addition to the lower rate of postoperative complications, the L-LRH group had additional favorable surgical outcomes including shorter operation time and lower blood loss volume than the O-ORH group (291 vs 368 min, P = 0.037 and 10 vs 485 mL, P < 0.0001). CONCLUSIONS: An initial laparoscopic approach would be favorable for patients undergoing repeat hepatectomies, as it leads to lower risk of postoperative complications. Compared with O-ORH, the advantage of the laparoscopic approach may be enhanced when it is repeatedly adopted.2023年06月, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 27(8) (8), 1621 - 1631, 英語, 国際誌研究論文（学術雑誌）
- Carnivorous plants often spark broad interest due to their specialized adaptations for trapping and consuming animals. These notable organisms not only fix carbon through photosynthesis, but they also obtain essential nutrients such as nitrogen and phosphate from their captured prey. In typical angiosperms, interactions with animals are usually confined to such processes as pollination and herbivory, but another layer of complexity in these interactions is added for carnivorous plants. Here, we introduce carnivorous plants and their associated organisms - ranging from their prey to their symbionts - and highlight biotic interactions beyond carnivory to discuss how the 'default' interactions typical for flowering plants have changed in the case of the carnivorous plants (Figure 1).2023年06月, Current biology : CB, 33(11) (11), R497-R500, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND: Larger sample volume can be obtained in one needle pass using an aspiration-type semi-automatic cutting biopsy needle (STARCUT® aspiration-type needle; TSK Laboratory, Tochigi, Japan) in comparison to the conventional semi-automatic cutting biopsy needle. OBJECTIVE: To evaluate and compare the safety and effectiveness of aspiration-type semi-automatic cutting biopsy needles and non-aspiration-type biopsy needles when performing computed tomography (CT)-guided core needle biopsies (CNBs). METHODS: A total of 106 patients underwent CT-guided CNB for chest lesions between June 2013 and March 2020 at our hospital. Non-aspiration-type cutting biopsy needles were used in 47 of these patients, while aspiration-type needles were used in the remaining 59 patients. All needles used were 18- or 20-gauge biopsy needles. Parameters, like forced expiratory volume in 1-second percent (FEV1.0%), the maximum size of the target lesion, puncture pathway distance in the lung, number of needle passes, procedure time, diagnostic accuracy, and incidence of complications, were measured. Comparisons were made between the needle-type groups. RESULTS: No significant difference was observed in terms of diagnostic accuracy. However, the procedure time was shorter and a lesser number of needle passes were required with the aspiration-type cutting biopsy needle compared to the non-aspiration-type needle. Pneumothorax and pulmonary hemorrhage were the complications encountered, however, their incidence was not significantly different between the two types of needles. CONCLUSIONS: The aspiration-type semi-automatic cutting biopsy needle had similar diagnostic accuracy as the non-aspiration-type biopsy needle, with added advantages of a lesser number of needle passes and shorter procedure time.2023年05月, Current medical imaging, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND/AIM: Recently, the Global Leadership Initiative on Malnutrition (GLIM), which includes the world's leading clinical nutrition societies, proposed the first global diagnostic criteria for malnutrition. However, the association between malnutrition diagnosed by the GLIM criteria and prognosis in patients with resected extrahepatic cholangiocarcinoma (ECC) remains unknown. This study aimed to investigate the predictive validity of the GLIM criteria for the prognosis of patients with resected ECC. PATIENTS AND METHODS: Between 2000 and 2020, 166 patients who underwent curative-intent resection for ECC were retrospectively analyzed. Prognostic significance of preoperative malnutrition diagnosed by the GLIM criteria was investigated using a multivariate Cox proportional hazards model. RESULTS: Eighty-five (51.2%) and 46 (27.7%) patients were diagnosed with moderate and severe malnutrition, respectively. Increased malnutrition severity tended to be correlated with increased lymph node metastasis rate (p-for-trend=0.0381). The severe malnutrition group had worse 1-, 3-, and 5-year overall survival rates than the normal (without malnutrition) group (82.2% vs. 91.2%, 45.6% vs. 65.1%, 29.3% vs. 61.5%, respectively, p=0.0159). In multivariate analysis, preoperative severe malnutrition was an independent predictor for poor prognosis (hazard ratio=1.68, 95% confidence interval=1.06-2.66, p=0.0282), along with intraoperative blood loss >1,000 ml, lymph node metastasis, perineural invasion, and curability. CONCLUSION: Severe preoperative malnutrition diagnosed by the GLIM criteria was associated with poor prognosis in patients who underwent curative-intent resection for ECC.2023年05月, Anticancer research, 43(5) (5), 2299 - 2308, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND: Post-transplantation weight control is important for long-term outcomes; however, few reports have examined postoperative weight change. This study aimed to identify perioperative factors contributing to post-transplantation weight change. METHODS: Twenty-nine patients who underwent liver transplantation between 2015 and 2019 with an overall survival of >3 years were analyzed. RESULTS: The median age, model for end-stage liver disease score, and preoperative body mass index (BMI) of the recipients were 57, 25, and 23.7, respectively. Although all but one recipient lost weight, the percentage of recipients who gained weight increased to 55% (1 month), 72% (6 months), and 83% (12 months). Among perioperative factors, recipient age ≤50 years and BMI ≤25 were identified as risk factors for weight gain within 12 months (P < .05), and patients with age ≤50 years or BMI ≤25 recipients gained weight more rapidly (P < .05). The recovery time of serum albumin level ≥4.0 mg/dL was not statistically different between the 2 groups. The weight change during the first 3 years after discharge was represented by an approximately straight line, with 18 and 11 recipients showing a positive and negative slope, respectively. Body mass index ≤23 was identified as a risk factor for a positive slope of weight gain (P <.05). CONCLUSIONS: Although postoperative weight gain implies recovery after transplantation, recipients with a lower preoperative BMI should strictly manage body weight as they may be at higher risk of rapid weight increase.2023年04月, Transplantation proceedings, 55(4) (4), 924 - 929, 英語, 国際誌研究論文（学術雑誌）
- 兵庫県外科医会, 2023年03月, 兵庫県外科医会会誌, 57, 13 - 15, 日本語
- BACKGROUND: Bile leakage is a major complication after liver transplantation and remains as a significant source of morbidity and mortality. In 2011, the International Study Group of Liver Surgery (ISGLS) defined bile leakage as a drain/serum bilirubin ratio ≥3. However, to our knowledge there is no literature assessing serum and drain bilirubin concentrations after liver transplantation. The aim of this study was to describe the natural postoperative changes in serum and drain fluid bilirubin concentrations in patients after liver transplantation. METHODS: We included 32 patients who underwent liver transplantation at Kobe University Hospital from January 2007 to December 2020. We enrolled 34 living donors who had no complications as the control group. RESULTS: The recipient serum total/direct bilirubin concentration were higher compared with the donors from postoperative day (POD) 1 to 5 with a statistical difference (P < .05). The recipient drain/serum total bilirubin ratio was lower than donors on POD 3 (0.89 ± 0.07 vs 1.53 ± 0.07: P < .0001), which was also confirmed by the recipient drain/serum direct bilirubin ratio (0.64 ± 0.10 vs 1.18 ± 0.09: P < .0001). On POD 3, the drain fluid volume (647.38 ± 89.47 vs 113.43 ± 86.8 mL: P < .001) and serum total bilirubin concentration (6.73 ± 0.61 vs 1.23 ± 0.60 mg/dL: P < .001) was higher in the recipients than in donors. Categorized in 2 groups, the higher drain fluid volume and bilirubin concentration recipients showed lower drain/serum total bilirubin ratio compared with the other group (P = .03) CONCLUSION: The drain/serum bilirubin ratio in the transplanted patients could be calculated lower compared with the hepatectomy patients because of high drain fluid volume and hyperbilirubinemia. Great care should be taken when assessing the bile leakage in liver transplant recipients using the ISGLS definition.2023年01月, Transplantation proceedings, 55(1) (1), 184 - 190, 英語, 国際誌研究論文（学術雑誌）
- Investigation of tumor assessment between two PET systems using various indices: comparison between PET/CT and PET/MRI systems.This study aimed to determine the comparability of tumor-uptake indices of 18F-FDG in positron emission tomography/computed tomography (PET/CT) and positron emission tomography/magnetic resonance imaging (PET/MRI). 2-[fluorine-18]-fluoro-2-deoxy-D-glucose (FDG) PET/CT and PET/MRI were performed on 55 patients with confirmed primary malignancies. PET/CT preceded PET/MRI in all examinations. Accumulation of 18F-FDG in lesions and normal organs (brain, liver) was measured. Maximum and peak standardized uptake values (SUVs; SUVmax and SUVpeak, respectively), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) with margin thresholds of SUV of 50% (MTV50%; TLG50%, respectively) were measured as indices for comparison of measurements in tumors. Comparative indices with tumor SUVmax and liver ratio (TLRmax), brain ratio (TBRmax) were calculated. These indices were compared between PET/CT and PET/MRI examinations. The data measured using PET/CT and PET/MRI showed significant correlations for all tumor indices. The correlation was strongest for SUVpeak (r = 0.933), followed by TBRmax (r = 0.929); and the index ratio of (PET/CT)/(PET/MRI) data was close to 1.0 for TLRmax (1.00 ± 0.22) and TBRmax (1.01 ± 0.21), followed by MTV50% (0.82 ± 0.33) and TLG50% (1.18 ± 0.45). The values of all indices showed strong correlations between PET/CT and PET/MRI examinations. Among them, TLRmax, TBRmax, MTV50%, and TLG50% showed a close value and may be useful for comparison of tumor evaluation between two PET systems.2023年, American journal of nuclear medicine and molecular imaging, 13(4) (4), 156 - 163, 英語, 国際誌研究論文（学術雑誌）
- Background: Myocardial blood flow quantification (MBF) is one of the distinctive features for cardiac positron emission tomography. The MBF calculation is mostly obtained by estimating the input function from the time activity curve in dynamic scan. However, there is a substantial risk of count-loss because the high radioactivity pass through the left ventricular (LV) cavity within a short period. We aimed to determine the optimal intraventricular activity using the noise equivalent count rate (NECR) analysis with simplified phantom model. Methods: Positron emission tomography computed tomography scanner with LYSO crystal and time of flight was used for phantom study. 150 MBq/mL of 13N was filled in 10 mL of syringe, placed in neck phantom to imitate end-systolic small LV. 3D list-mode acquisition was repeatedly performed along radioactive decay. Net true and random count rate were calculated and compared to the theoretical activity in the syringe. NECR curve analysis was used to determine the optimal radioactive concentration. Result: The attenuation curves showed good correlation to the theoretical activity between 20 to 370, and 370 to 740 MBq (r2=1.0 ± 0.0001, p<0.0001; r2=0.99 ± 0.0001, p<0.0001 for 20 to 370, and 370 to 740, respectively), while did not over 740 MBq (p=0.62). NECR analysis revealed that the peak rate was at 2.9 Mcps, there at the true counts were significantly suppressed. The optimal radioactive concentration was determined as 36 MBq/mL. Conclusion: Simulative analysis for high-dose of 13N using the phantom imitating small LV confirmed that the risk of count-loss was increased. The result can be useful information in assessing the feasibility of MBF quantification in clinical routine.2023年, Annals of nuclear cardiology, 9(1) (1), 33 - 39, 英語, 国内誌研究論文（学術雑誌）
- Background: Due to the limitation of spatial resolution, cardiac nuclear medicine images have not been applied to feature-tracking method to automatic extraction of myocardial contours. We have successfully applied the feature-tracking method to high-resolution cine 13N-ammonia positron emission tomography (PET) images to calculate the regional myocardial strains. Here, we investigate the potential of 13N-ammonia PET-derived strain to detect ischemia-related wall motion abnormality. Methods: Data of adenosine-stress/rest 13N-ammonia PET for 95 coronary artery disease patients was retrospectively analyzed. Using an original algorithm dedicated to 13N-ammonia PET, the longitudinal strain (LS) corresponding to the three main coronary artery territories [right coronary artery (RCA), left anterior descending artery (LAD), and left circumflex coronary artery (LCX)] was calculated from semi-automatic endocardial contours extraction on cine 13N-ammonia PET images of the left ventricular long-axis. The presence of ischemia in three main territories was determined from rest and stress-perfusion images. Results: In all three coronary territories, LS at stress was significantly smaller at rest in the ischemic region RCA: -19.2±8.0% vs. -22.7±6.1%, LAD: -19.0±6.9% vs. -24.4±6.4%, LCX: -20.5%±7.6% vs. -22.6±6.9%). In contrast, in the non-ischemic region, there was no significant difference between the LS at stress and at rest. Receiver-operating-characteristic analysis revealed that using the optimal cutoff of the LS ratio of stress to rest, ischemia could be diagnosed with area under the curve of 0.82 in the RCA, 0.86 in the LAD, and 0.69 in the LCX. Conclusions: Myocardial strain derived from endocardial feature-tracking of 13N-ammonia PET cine imaging is reduced in the ischemia induced by adenosine-stress. The LS ratio of stress to rest may detect wall motion abnormality related to ischemia.2023年, Annals of nuclear cardiology, 9(1) (1), 26 - 32, 英語, 国内誌研究論文（学術雑誌）
- BACKGROUND: Laparoscopic caudate lobe resection is a challenging procedure. Several researchers have reported the safety of laparoscopic liver resections;1.Transl Gastroenterol Hepatol. 1:56;2.Asian J Endosc Surg. 12:232-236;3.Ann Surg Oncol. 26:2980; however, a standardized procedure has not yet been established. Herein, we present a video showing laparoscopic Spiegel lobectomy in a patient with 6-cm hepatocellular carcinoma (HCC) using a novel approach. PATIENT AND METHODS: A 63-year-old man with a caudate lobe HCC was referred to our hospital. Computed tomography showed a 5 × 6 cm2 HCC located in the Spiegel lobe, which profoundly displaced the inferior vena cava (IVC) to the lower right side, and mobilization of the Spiegel lobe was considered difficult. To perform the dissection between the Siegel lobe and IVC safely, we performed parenchymal transection along the ventral side of the IVC initially. The Spiegel lobe was then dislocated to the left side of the IVC. We dissected the left lateral side of the IVC, including the proper hepatic vein draining the caudate lobe and the left IVC ligament with a safe operative field, and successfully removed the Spiegel lobe with large HCC. RESULTS: The operation time was 383 min. The blood loss was 10 mL. The patient was discharged on the seventh postoperative day without any complications. Histopathological examination revealed well-differentiated HCC with a negative surgical margin. CONCLUSIONS: Laparoscopic medial-to-lateral approach with initial parenchymal transection at the medial side of the Spiegel lobe followed by dissection of the left lateral side of the IVC is considered as a safe and effective procedure for large tumors in the Spiegel lobe.2023年01月, Annals of surgical oncology, 30(1) (1), 381 - 382, 英語, 国際誌研究論文（学術雑誌）
- 2023年01月, Annals of surgical oncology, 30(1) (1), 383 - 383, 英語, 国際誌研究論文（学術雑誌）
- INTRODUCTION: With the aging of the population in Japan, gallbladder cancer (GBC) in the elderly is increasing. However, the available clinical data are limited, and the optimal treatment is still controversial. The aim of this study was to evaluate the benefit of surgical resection in GBC patients ≥75 years of age. METHODS: A retrospective single center analysis of patients who had undergone surgical resection for GBC between 2000 and 2019 was carried out. Patients aged ≥75 years (elderly group, n = 24) or <75 years (younger group, n = 50) were compared. RESULTS: Both younger and elderly patients exhibited similar clinicopathological characteristics, but comorbidity in the latter was significantly greater, as was the frequency of less invasive surgery. Nonetheless, the incidence of postoperative complications was similar in elderly and younger patients. The proportion of patients receiving adjuvant chemotherapy was lower in the elderly. Overall survival of elderly and younger patients was not significantly different (65.0 vs 62.4% at 5 years, P = .600). In multivariate analysis, residual tumor status but not age was an independent prognostic factor. DISCUSSION: This study demonstrated that appropriate surgical treatment of elderly GBC patients was safe and effective, despite their having more comorbidities and lower rates of adjuvant chemotherapy than younger patients.2022年11月, The American surgeon, 31348221136570 - 31348221136570, 英語, 国際誌研究論文（学術雑誌）
- (株)医薬情報研究所, 2022年11月, 新薬と臨牀, 71(11) (11), 1234 - 1234, 日本語
- (株)医薬情報研究所, 2022年11月, 新薬と臨牀, 71(11) (11), 1234 - 1234, 日本語進行肝細胞癌におけるconversion surgeryの妥当性
- BACKGROUND: Anatomic liver resection (ALR) has been established to eliminate the tumor-bearing hepatic region with preservation of the remnant liver volume for liver malignancies. Recently, laparoscopic ALR has been widely applied; however, there are few reports on laparoscopic segmentectomy 2. This study aimed to present the standardization of laparoscopic segmentectomy 2 with surgical outcomes. METHODS: This study included seven patients who underwent pure laparoscopic segmentectomy 2 by the Glissonean approach from January 2020 to December 2021. Four of them had hepatocellular carcinoma, two had colorectal liver metastasis, and one had hepatic angiomyolipoma, which was preoperatively diagnosed with hepatocellular carcinoma. In all patients, preoperative three-dimensional (3D) simulation images from dynamic CT were reconstructed using a 3D workstation. The layer between the hepatic parenchyma and the Glissonean pedicle of segment 2 (G2) was dissected to encircle the root of G2. After clamping or ligation of the G2, 2.5 mg of indocyanine green was injected intravenously to identify the boundaries between segments 2 and 3 with a negative staining method under near-infrared light. Parenchymal transection was performed from the caudal side to the cranial side according to the demarcation on the liver surface, and the left hepatic vein was exposed on the cut surface if possible. RESULTS: The mean operative time for all patients was 281 min. The mean blood loss was 37 mL, and no transfusion was necessary. Estimated liver resection volumes significantly correlated with actual liver resection volumes (r = 0.61, P = 0.035). After the operation, one patient presented with asymptomatic deep venous and pulmonary thrombosis, which was treated with anticoagulant therapy. The mean length of hospital stay was 8.9 days. CONCLUSION: Laparoscopic segmentectomy 2 by the Glissonean approach is a feasible and safe procedure with the preservation of the nontumor-bearing segment 3 for liver tumors in segment 2.2022年11月, Surgical endoscopy, 36(11) (11), 8600 - 8606, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND/AIM: Atezolizumab plus bevacizumab and lenvatinib are the key drugs in the current systemic chemotherapeutic regimen for hepatocellular carcinoma (HCC). Studies have reported the potential effectiveness of lenvatinib introduction after an atezolizumab plus bevacizumab treatment; however, the therapeutic effectiveness of a lenvatinib rechallenge after an atezolizumab plus bevacizumab treatment remains unclear. PATIENTS AND METHODS: Thirteen consecutive patients who were rechallenged with lenvatinib after clinical failure following treatments with lenvatinib and atezolizumab plus bevacizumab were included. A comparative study was conducted on the duration and treatment efficacy of the first and second lenvatinib treatments and on the pre- and post-treatment liver function. RESULTS: The median ratios of the 1-month post-treatment alpha-fetoprotein (AFP) levels to the pretreatment AFP levels were 0.750 and 0.667 for the first and second lenvatinib treatments, respectively, without significant difference (p=0.9327). Meanwhile, the median ratios of the 1-month post-treatment albumin-bilirubin (ALBI) scores to the pretreatment ALBI scores were 1.063 and 0.827 for the first and second lenvatinib treatments, respectively, with significant difference (p=0.015). The median duration of the second lenvatinib treatment was significantly shorter than that of the first lenvatinib treatment [2.8 months (range=0.9-4.7 months) vs. 8.7 months (range=3.1-29.7 months)]. CONCLUSION: Lenvatinib re-administration after atezolizumab plus bevacizumab treatment can act as a double-edged sword, as it exerts an anti-tumor effect while being associated with potential liver function deterioration. However, this treatment sequence can be useful, and requires careful monitoring of the transitions in the liver function and the patient's performance status.2022年11月, Anticancer research, 42(11) (11), 5479 - 5486, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND: Resecting liver tumors located in Couinaud's segment VII is challenging; the efficacy and safety of laparoscopic liver resection for segment VII lesions compared to open liver resection remain unclear. METHODS: Medical records of 84 patients who underwent liver resection of segment VII at Kobe University Hospital and Hyogo Cancer Center between 2010 and 2021 were retrospectively analyzed. Surgical outcomes were compared between laparoscopic liver resection and open liver resection groups using propensity matching analysis. RESULTS: Thirty-one and 53 patients underwent laparoscopic liver resection and open liver resection, respectively. After propensity matching, 29 patients were included in each group. The laparoscopic liver resection group had a significantly longer operation time (407 vs. 305 min, P = 0.002), lower blood loss (100 vs. 230 mL, P = 0.004), and higher postoperative alanine aminotransferase levels (436 vs. 252 IU/L, P = 0.008) than the open liver resection group. In patients with liver cirrhosis, the proportion of patients with postoperative liver-specific complications was higher in the laparoscopic liver resection group than in the open liver resection group (57% vs 11%, P = 0.049), although there was no significant difference in postoperative liver-specific complication rates between the groups in patients without liver cirrhosis. CONCLUSIONS: For liver resection of segment VII, laparoscopic liver resection led to higher postoperative liver damage than open liver resection. Open liver resection may be better for patients with liver cirrhosis to avoid postoperative liver-specific complications. Laparoscopic liver resection could be an acceptable procedure for patients without liver cirrhosis, with some merits such as less blood loss.2022年06月, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 26(11) (11), 2274 - 2281, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND: Optimal treatment strategies for advanced hepatocellular carcinoma (HCC) with macroscopic portal vein tumor thrombus (PVTT) remain controversial. Therefore, this study aimed to assess the impact and predictive factors of hepatectomy for HCC with macroscopic PVTT. METHODS: This study included 100 patients who presented with intraoperatively confirmed PVTT extending to the first portal branch (Vp3), main portal trunk, or opposite-side portal branch (Vp4) between June 2000 and December 2019. Their postoperative outcomes and predictive factors for survival were evaluated. RESULTS: Of the 100 patients, 37 (37%) and 63 (63%) had Vp3 and Vp4 PVTTs, respectively. Moreover, 42 (42%) and 58 (58%) patients underwent R0/1 and R2 hepatectomies, respectively. The median survival time (MST) of all patients with Vp3/4 PVTT was 14.5 months; the 1- and 3-year overall survival rates were 59.6 and 16.8%, respectively. The MSTs of patients with Vp3 and Vp4 PVTTs were 16.1 and 14.3 months, respectively (P = 0.7098). The MSTs of patients who underwent R0/1 and R2 hepatectomies were 14.3 and 14.9 months, respectively (P = 0.3831). All assessed tumor factors (including the Vp status [Vp3 or Vp4], type of resection [R0/1 or R2], intrahepatic maximal tumor size, intrahepatic tumor number, and the existence of extrahepatic metastasis) did not influence the overall survival significantly. CONCLUSIONS: Tumor factors, such as the presence of a Vp3/4 PVTT, have a strong impact on survival; however, other multiple tumor factors have a limited impact. Hepatectomy can be an effective treatment option for HCC with Vp3/4 PVTT, and its indications should be considered.2022年04月, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 26(4) (4), 822 - 830, 英語, 国際誌研究論文（学術雑誌）
- INTRODUCTION: Although the relationship between systemic inflammatory responses and prognosis has been known in various cancers, it remains unclear which scores are most valuable for determining the prognosis of extrahepatic cholangiocarcinoma. We aimed to verify the usefulness of various inflammation-based scores as prognostic factors in patients with resected extrahepatic cholangiocarcinoma. METHODS: We analyzed consecutive patients undergoing surgical resection for extrahepatic cholangiocarcinoma at our institution between January 2000 and December 2019. The usefulness of the following inflammation-based scores as prognostic factor was investigated: Glasgow prognostic score (GPS), modified Glasgow prognostic score (mGPS), neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), lymphocyte to monocyte ratio (LMR), prognostic nutrition index (PNI), C-reactive protein to albumin ratio (CAR), controlling nutritional status (CONUT), and prognostic index (PI). RESULTS: A total of 169 patients were enrolled in this study. Of the nine scores, CAR and CONUT indicated prognostic value. Furthermore, multivariate analysis for overall survival revealed that high CAR (>0.23) was an independent prognostic factor (HR: 1.816, 95%CI: 1.135-2.906, p=0.0129), along with lymph node metastasis and curability. There was no difference in tumor staging and short-term outcomes between the low CAR (≤ 0.23) and high CAR groups. CONCLUSIONS: CAR was the most valuable prognostic score in patients with resected extrahepatic cholangiocarcinoma.2022年01月, Digestive surgery, 39(2-3) (2-3), 65 - 74, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND: Although liver transplantation is widely accepted as the therapeutic strategy for end-stage liver failure, complication of hepatic venous outflow obstruction remains lethal. Currently, ensuring a single wide orifice in both the graft and recipient inferior vena cava has been proposed to avoid hepatic venous outflow obstruction with no theoretical concept. METHODS: We herein report a standardization technique for the reconstruction of the hepatic vein based on the causal analysis. RESULTS: During the put-in process, the graft must be positioned in contact with the recipient diaphragm and slightly pushed to the cranial direction to simulate the state after abdominal closure. Because there is no extra space between the graft and diaphragm, the graft could not rotate about the anastomotic site of the inferior vena cava toward the diaphragm after abdominal closure as the intestinal pressure increases, and accordingly hepatic venous outflow obstruction does not develop. CONCLUSIONS: With this concept, all transplant surgeons can successfully and easily perform hepatic vein reconstruction without total clamping of the inferior vena cava and without outflow block.2021年12月, Transplantation proceedings, 53(10) (10), 2934 - 2938, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND/AIM: Sarcopenia has been reported to be a significant prognostic factor in patients with hepatocellular carcinoma in recent years. This study aimed to clarify the prognostic significance of sarcopenia in advanced hepatocellular carcinoma treated with reductive hepatectomy. PATIENTS AND METHODS: We retrospectively analyzed 93 patients who underwent reductive hepatectomy for advanced hepatocellular carcinoma. RESULTS: Median survival time of the sarcopenia group (16.4 months) was significantly shorter than that of the non-sarcopenia group (20.4 months). The overall survival rates at 1, 3, and 5 years of the sarcopenia group were significantly lower than those of the non-sarcopenia group (57.9%, 8.6%, and 2.9% vs. 67.3%, 29.2%, and 15.7%, respectively; p=0.035). On multivariate analysis, sarcopenia was a significant risk factor of overall survival (hazard ratio=1.60, 95% confidence interval=1.00-2.56, p=0.049). CONCLUSION: Sarcopenia was a significant prognostic factor of survival after reductive hepatectomy in advanced hepatocellular carcinoma.2021年11月, Anticancer research, 41(11) (11), 5775 - 5783, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND/AIM: While there is increasing evidence supporting the role of several first- and second-line treatment regimens for advanced hepatocellular carcinomas (HCC), the clinical relevance of rechallenge treatment with previously administered drugs, however, remains to be explored. PATIENTS AND METHODS: Five consecutive patients with advanced HCC who received lenvatinib rechallenge treatment after ramucirumab were assessed. RESULTS: All patients were clinically diagnosed with failure after ramucirumab treatment, and the frequencies of ramucirumab administration before lenvatinib re-administration ranged from 3 to 11. The alfa-fetoprotein level in four of five patients decreased 1 month after the lenvatinib rechallenge. Radiological findings via the modified Response Evaluation Criteria in Solid Tumors showed stable diseases in four patients and a partial response in one. CONCLUSION: Rechallenge treatment with lenvatinib after ramucirumab can be effective, and may be a treatment option for HCC in cases wherein the disease progressed after an initial response to lenvatinib treatment.2021年09月, Anticancer research, 41(9) (9), 4555 - 4562, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND: Plexiform schwannoma is one of the least common variants of schwannoma, accounting for only 5% of all schwannoma cases. It generally occurs in the skin and subcutaneous tissues and is uncommon in deep soft tissue or viscera. We present an extremely rare case of plexiform schwannoma arising from the peripancreatic plexus. CASE PRESENTATION: A 29-year-old man presented with hyperglycemia detected during a medical checkup. He was diagnosed with type 1 diabetes based on the clinical findings and laboratory tests. During the diagnostic process for diabetes, a 2.5 cm mass was incidentally detected in the pancreas by abdominal ultrasound. Contrast-enhanced computed tomography revealed a mass that was gradually enhanced at the body and tail of the pancreas. Magnetic resonance imaging revealed low signal intensity of the mass on T1-weighted images and high signal intensity on T2-weighted and diffusion-weighted images. Magnetic resonance cholangiopancreatography showed no abnormal findings in the main pancreatic duct. Endoscopic ultrasonography (EUS) showed a lobulated, low-echoic mass with a clear boundary. EUS-guided fine needle biopsy was performed, and spindle-shaped cells that were diffusely immunopositive for S-100 and negative for c-kit and desmin were detected, resulting in a diagnosis of a neurogenic tumor arising from the pancreas or the peripancreatic nerve plexus. The patient underwent laparoscopic spleen-preserving distal pancreatectomy. Although the tumor was connected to the splenic plexus, the splenic artery could be divided along its adventitial plane. Macroscopic findings of the excised tumor consisted of multiple yellowish-white nodules, and its histopathological features were consistent with plexiform schwannoma. There was no pancreatic tissue on the dorsal surface of the tumor, which suggested that the tumor arose from the peripancreatic nerve plexus. CONCLUSIONS: The findings documented herein can aid in the differential diagnosis of peripancreatic schwannoma and in planning appropriate treatment.2021年08月, Surgical case reports, 7(1) (1), 199 - 199, 英語, 国際誌研究論文（学術雑誌）
- Severity assessment in biomedical research is required by the European authorities. Therefore, a variety of score sheets are available. The first score sheets were designed and introduced by Morton and Griffith (M&G) in 1985, to assess pain and distress in animals. Score sheets are an important part of the 3R principles to evaluate the degree of severity in different studies. Here, we used a modified score sheet from M&G for severity assessment of 12 Aachen minipigs after partial liver resection for safety testing of a novel synthetic sealant (VIVO-107). The control group was treated with the clinical standard fibrin. Estimation of recovery status of both groups was performed from the day of surgery to postoperative day 7 using a score sheet. Included parameters were blood loss during the surgical procedure, general state, spontaneous behaviour and clinical results. Values from 0 to 20 were graded for each category and resulted in the degree of strain (DS) from DS0 to DS4. An increasing DS indicated higher severity. Suitability of the implemented score sheet was evaluated. Higher score points were documented almost exclusively as an outcome of the clinical results, influenced mainly by increased temperature in the fibrin treated control group, whereas, spontaneous behaviour had only slight influence and general state had no influence. The average score seven days after surgery was <2. The laparotomy, where the partial liver resection is a part, is rated as moderate severity in the EU Directive 2010/63, while the assessment done in the present study hints to a mild severity of the model in our hands.2020年06月, Laboratory animals, 54(3) (3), 251 - 260, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND: Topical hemostatic agents are useful when hepatic hemorrhage is difficult to control. The aim of this study was to evaluate the hemostatic efficacy and safety of a biodegradable polyurethane-based adhesive, MAR VIVO-107 (MAR), in comparison with a clinically used fibrin glue. METHODS: Thirty female New Zealand white rabbits were randomly assigned to 3 study groups as follows: MAR (n = 10), fibrin glue (n = 10), and saline groups (n = 10). After standardized partial liver resection was performed, each agent was immediately applied to the wound area. Bleeding time until hemostasis and blood loss were recorded. After 7 days, body weight, hematology parameters, and serum levels of aspartate aminotransferase, alanine aminotransferase, and lactate dehydrogenase were measured. Simultaneously, the severity of intra-abdominal adhesion was evaluated. RESULTS: The mean bleeding time in the MAR (38 ± 10 s) and fibrin glue groups (65 ± 17 s) was significantly shorter than that in the saline group (186 ± 12 s). Similarly, the mean blood loss in the MAR (9 ± 3 g) and fibrin glue groups (9 ± 3 g) was significantly less than that in the saline group (23 ± 4 g). No significant differences in bleeding time and blood loss were found between the MAR and fibrin glue groups. The postoperative survival rate was 100% in all the groups. Body weight as well as hematological and serum biochemical values on day 7 were within the small and physiological range when compared with the preoperative baseline values, and significant differences were not detected among the MAR, fibrin glue, and saline groups. The severities of adhesion were similar between the 3 groups. CONCLUSION: Our data demonstrated that MAR was not inferior to fibrin glue in terms of hemostatic efficacy and safety.2018年, European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 59(1-2) (1-2), 48 - 57, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND: Despite modern surgical techniques, insufficient hemostasis after liver trauma is still a major cause of morbidity and mortality after injury. Therefore, efficient hemostatic agents are indicated. In this study, we evaluated the hemostatic efficacy of a novel synthetic wound adhesive (MAR-VIVO-107) based on polyurethane/polyurea, compared with a widely used fibrin adhesive (Tisseel). MATERIALS AND METHODS: Twelve German Landrace pigs were randomly assigned to 2 groups. The animals were operated under sterile conditions. A midline laparotomy was performed and the left liver lobe was isolated and resected, using a surgical scissor, in order to induce hepatic trauma. MAR-VIVO-107 or Tisseel was applied to the resected area. The animals were monitored for 60 minutes; thereafter, they were sacrificed under anesthesia. Blood and tissue samples were collected pre- and postresection for biochemical and hematological analyses. RESULTS: MAR-VIVO-107 versus Tisseel (mean ± SD, P value)-postsurgical survival rate was 100% in both groups. Bleeding time was significantly higher in Tisseel compared with MAR-VIVO-107 (10.3 ± 5.0 vs 3.7 ± 1.5 minutes, P = .0124). In trend, blood loss was less in the MAR-VIVO-107 group (54.3 ± 34.9 vs 105.5 ± 65.8 g, P = .222). Aspartate transaminase levels were significantly lower in the MAR-VIVO-107 group when compared with the Tisseel group (39.0 ± 10.0 vs 72.4 ± 23.4 U/L, P = .0459). CONCLUSION: The efficacy of MAR-VIVO-107 and comparable performance to the gold standard fibrin have been shown under pre-clinical conditions. MAR-VIVO-107 permits hemorrhage control within seconds, even in wet environment.2017年10月, Surgical innovation, 24(5) (5), 423 - 431, 英語, 国際誌研究論文（学術雑誌）
- AIM: To compare a novel, fully synthetic, polyurethane based glue (MAR-1) to fibrin sealant in a partial liver resection rat model. METHODS: After 50% resection of the lateral left liver lobe in male Wistar rats (n = 7/group/time point), MAR-1, Fibrin or NaCl was applied. After 14, 21 and 90 postoperative days, sealant degradation, intra-abdominal adhesions were scored, and histological examination of liver tissue was performed. RESULTS: (Mean ± SEM) (MAR-1 vs Fibrin vs NaCl). Bleeding mass was significantly higher in NaCl (3.36 ± 0.51 g) compared to MAR-1 (1.44 ± 0.40 g) and Fibrin (1.16 ± 0.32 g). At 14 and 90 d, bleeding time was significantly lower in MAR-1 (6.00 ± 0.9 s; 13.57 ± 3.22 s) and Fibrin (3.00 ± 0.44 s; 22.2 ± 9.75 s) compared to NaCl (158.16 ± 11.36 s; 127.5 ± 23.3 s). ALT levels were significantly higher in MAR-1 (27.66 ± 1 U/L) compared to Fibrin (24.16 ± 0.98 U/L) and NaCl (23.85 ± 0.80 U/L). Intrabdominal adhesions were significantly lower in MAR-1 (11.22% ± 5.5%) compared to NaCl (58.57% ± 11.83%). Degradation of the glue was observed and MAR-1 showed almost no traces of glue in the abdominal cavity as compared to the Fibrin (10% ± 5% 14 d; 7% ± 3% 21 d). Survival showed no significant differences between the groups. CONCLUSION: Compared to Fibrin, MAR-1 showed similar hemostatic properties, no adverse effects, and is biocompatible. Further studies on adhesion strength and biodegradability of synthetic sealants are warranted.2017年08月, World journal of hepatology, 9(24) (24), 1030 - 1039, 英語, 国際誌研究論文（学術雑誌）
- Recommendation for severity assessment following liver resection and liver transplantation in rats: Part I.Score sheets were first introduced 30 years ago to assess pain, distress and suffering in animals. To date, however, there is still no general agreement on their use in research practice, and only a few publications can be found on this topic. In the present work, we demonstrate the use of a special score sheet for severity assessment in the first three postoperative days in two showcased studies performed on Wistar and Lewis rats undergoing liver resection or orthotopic liver transplantation, respectively. Scoring of different criteria and the total score were evaluated within each intervention. Additionally, both procedures were compared regarding their degree of severity. Suitability of these score sheets was evaluated for assessing severity of the procedures and these showed a minor severity within each investigated study. A comparison of both studies showed slightly higher scores involving liver transplantation. In contradiction to the common classification of these procedures as a moderate severity grade the score sheets applied here indicates a minor severity grade within each investigated study. Also, limitations and possible improvements in the design of our score sheets for defined interventions are reconsidered.2016年12月, Laboratory animals, 50(6) (6), 459 - 467, 英語, 国際誌研究論文（学術雑誌）
- Severity assessment in rabbits after partial hepatectomy: Part II.Although the recognition of pain, distress and discomfort has already been described in 1985 by Morton and Griffiths there is still very little known about the establishment of score sheets especially, regarding post-surgical pain and severity assessment for laboratory animals such as rabbits. In this paper we describe the estimation of severity and recovery status of 36 female New Zealand White rabbits (NZW) in a standardized liver resection model using two different adhesive treatments and one control group. Welfare was assessed at 3-4 consecutive days after surgery using a scoring system which included the following criteria: body weight, general state, clinical results, spontaneous behavior and clinical examination. Values could range from 0 to 20 where increasing values indicated increasing severity with a predefined humane endpoint for a score ≥20 points. Documented score points were almost exclusively a result of body weight loss, whereas clinical signs and general health status had no influence on the overall sum of points scored. Behavioral variation was solely observed postoperatively, within the first 24 h, with an average score ≤1. In contrast to the classification of a laparotomy as a moderate procedure in the EU Directive 2010/63 (annex VIII) the assessment herein presented showed a mild burden in all groups according to the scoring system used. The partial hepatectomy itself, as well as the adhesive treatment using either synthetic glue VIVO-107 or fibrin glue, were well tolerated.2016年12月, Laboratory animals, 50(6) (6), 468 - 475, 英語, 国際誌研究論文（学術雑誌）
- BACKGROUND: Although several publications have reported donor morbidities, deterioration of liver function, which may cause posthepatectomy liver failure (PHLF), was not assessed specifically. METHODS: The incidence of PHLF proposed by the International Study Group of Liver Surgery (ISGLS-PHLF) was analyzed among 257 living donors. ISGLS-PHLF was defined by an increased international normalized ratio and hyperbilirubinemia on or after postoperative day 5. RESULTS: ISGLS-PHLF was identified in 21 donors (8%), of which 18 (85.7%) were grade A, 2 (9.5%) were grade B, and 1 (4.8%) was grade C. The average hospital stay without ISGLS-PHLF was 15 ± 1 days, which extended along with increasing grades (p = 0.03). In univariate analysis, right hepatectomy was significantly associated with the incidence of ISGLS-PHLF (p = 0.02), and right hepatectomy (p = 0.002) and operation time (p = 0.01) in multivariate analysis. Of 176 right lobe donors, 19 (10.8%) developed ISGLS-PHLF, of which 16 (84.2%) were grade A, 2 (10.5%) were grade B, and 1 (5.3%) was grade C. Operation time was significantly associated with the incidence of ISGLS-PHLF in univariate (p = 0.002) and multivariate (p = 0.003) analyses. CONCLUSIONS: Right lobe donation surgery is associated with a higher incidence of ISGLS-PHLF.2016年04月, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 20(4) (4), 757 - 64, 英語, 国際誌研究論文（学術雑誌）
- UNLABELLED: To develop a biodegradable clip, the equivalent plastic strain distribution during occlusion was evaluated by the finite element analysis (FEA) using the material data of pure Mg. Since the FEA suggested that a maximum plastic strain of 0.40 is required to allow the Mg clips, the alloying of magnesium with essential elements and the control of microstructure by hot extrusion and annealing were conducted. Mechanical characterization revealed that the Mg-Zn-Ca alloy obtained by double extrusion followed by annealing at 673K for 2h possessed a fracture strain over 0.40. The biocompatibility of the alloy was confirmed here by investigating its degradation behavior and the response of extraperitoneal tissue around the Mg-Zn-Ca alloy. Small gas cavity due to degradation was observed following implantation of the developed Mg-Zn-Ca clip by in vivo micro-CT. Histological analysis, minimal observed inflammation, and an only small decrease in the volume of the implanted Mg-Zn-Ca clip confirmed its excellent biocompatibility. FEA using the material data for ductile Mg-Zn-Ca also showed that the clip could occlude the simulated vessel without fracture. In addition, the Mg-Zn-Ca alloy clip successfully occluded the renal vein. Microstructural observations using electron backscattering diffraction confirmed that dynamic recovery occurred during the later stage of plastic deformation of the ductile Mg-Zn-Ca alloy. These results suggest that the developed Mg-Zn-Ca alloy is a suitable material for biodegradable clips. STATEMENT OF SIGNIFICANCE: Since conventional magnesium alloys have not exhibited significant ductility for applying the occlusion of vessels, the alloying of magnesium with essential elements and the control of microstructure by hot extrusion and annealing were conducted. Mechanical characterization revealed that the Mg-Zn-Ca alloy obtained by double extrusion followed by annealing at 673K for 2h possessed a fracture strain over 0.40. The biocompatibility of the alloy was confirmed by investigating its degradation behavior and the response of extraperitoneal tissue around the Mg-Zn-Ca alloy. Finite element analysis using the material data for the ductile Mg-Zn-Ca alloy also showed that the clip could occlude the simulated vessel without fracture. In addition, the Mg-Zn-Ca alloy clip successfully occluded the renal vein. Microstructural observations using electron backscattering diffraction confirmed that dynamic recovery occurred during the later stage of plastic deformation of the ductile Mg-Zn-Ca alloy.2016年01月, Acta biomaterialia, 29, 468 - 476, 英語, 国際誌研究論文（学術雑誌）
- 2015年11月, TRANSPLANT INTERNATIONAL, 28, 138 - 138, 英語INCIDENCE OF POSTHEPATECTOMY LIVER FAILURE AS DEFINED BY ISGLS AMONG LIVING LIVER DONORS
- (株)癌と化学療法社, 2015年09月, 癌と化学療法, 42(9) (9), 1111 - 1114, 日本語
- Post-transplant lymphoproliferative disorder (PTLD) is a well-known complication after transplantation. A living donor liver transplantation was performed on a 31-year-old man for fulminant hepatitis. He again developed liver dysfunction after 7 months. He was diagnosed as having acute cellular rejection and the steroid pulse therapy introduced resulted in little improvement. He gradually developed a high fever and right axillary lymphadenopathy appeared. Chest computed tomography (CT) was performed revealing small lung nodules and axillary lymphadenopathy. Because his serological status for Epstein-Barr virus was positive, PTLD was highly suspected and immunosuppression treatment was withdrawn with little improvement. One week later, he developed tachycardia. Chest CT was re-performed revealing an infiltration to the left cardiac chamber. For diagnosis, axillary lymph node biopsy was performed and during the procedure, he developed ventricular tachycardia (VT). Immunohistological staining revealed PTLD of T lymphocytes, and chemotherapy was introduced on the same day he developed VT. After two cycles of tetrahydropyranyl, adriamycin, cyclophosphamide, vincristine, prednisolone and etoposide treatment, he completely recovered. This is a first case report of severe PTLD with VT, and our case implies the feasibility of chemotherapy after the appearance of dissemination symptoms.2015年03月, Hepatology research : the official journal of the Japan Society of Hepatology, 45(3) (3), 356 - 62, 英語, 国際誌研究論文（学術雑誌）
- (株)癌と化学療法社, 2014年11月, 癌と化学療法, 41(12) (12), 2071 - 2073, 日本語
- (株)癌と化学療法社, 2014年11月, 癌と化学療法, 41(12) (12), 2107 - 2109, 日本語
- BACKGROUND: Posthepatectomy liver failure (PHLF) is a major complication after hepatectomy. As there was no standardized definition, the International Study Group of Liver Surgery (ISGLS) defined PHLF as increased international normalized ratio and hyperbilirubinemia on or after postoperative day 5 in 2010. We evaluated the impact of the ISGLS definition of PHLF on hepatocellular carcinoma (HCC) patients. METHODS: We retrospectively analyzed 210 consecutive HCC patients who underwent curative hepatectomy at our facility from 2005 to 2010. The median follow-up period after hepatectomy was 35.2 months. RESULTS: Thirty-nine (18.6%) patients fulfilled the ISGLS definition of PHLF. Overall survival (OS) rates at 1, 3, and 5 years in patients with/without PHLF were 69.1/93.5, 45.1/72.5, and 45.1/57.8%, respectively (P = 0.002). Recurrence-free survival (RFS) rates at 1, 3, and 5 years in patients with/without PHLF were 40.9/65.9, 15.7/38.3, and 15.7/20.3%, respectively (P = 0.003). Multivariate analysis revealed that PHLF was significantly associated with both OS (P = 0.047) and RFS (P = 0.019). Extent of resection (P < 0.001), intraoperative blood loss (P = 0.002), and fibrosis stage (P = 0.040) were identified as independent risk factors for developing PHLF. CONCLUSION: The ISGLS definition of PHLF was associated with OS and RFS in HCC patients, and long-term survival will be improved by reducing the incidence of PHLF.2014年04月, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 18(4) (4), 729 - 36, 英語, 国際誌研究論文（学術雑誌）
- (株)医薬情報研究所, 2014年03月, 新薬と臨牀, 63(3) (3), 479 - 479, 日本語
- (株)癌と化学療法社, 2013年11月, 癌と化学療法, 40(12) (12), 1681 - 1683, 日本語
- 2013年10月, HEPATOLOGY, 58, 230A - 230A, 英語Dual Treatment; A Novel Strategy for Highly-Advanced Hepatocellular carcinoma
- 2013年10月, HEPATOLOGY, 58, 781A - 781A, 英語Usefulness of 99mTc-GSA scintigraphy on preoperative evaluation of liver function for hepatectomy
- 2013年10月, HEPATOLOGY, 58, 775A - 775A, 英語Graft Type Significantly Associates with the Incidence of Posthepatectomy Liver Failure Defined by ISGLS in Living Donors after Hepatectomy
- (株)医薬情報研究所, 2012年12月, 新薬と臨牀, 61(12) (12), 2677 - 2677, 日本語
- (株)癌と化学療法社, 2012年11月, 癌と化学療法, 39(12) (12), 1825 - 1827, 日本語
- 2012年10月, HEPATOLOGY, 56, 518A - 519A, 英語Long-Term Outcomes and Prognostic Factors with Reductive Hepatectomy and Sequential Percutaneous Isolated Hepatic Perfusion for Multiple Bilobar Hepatocellular Carcinoma
- 2012年10月, HEPATOLOGY, 56, 519A - 519A, 英語Fragility Index, a Novel Predictor to Assess Deterioration Speed of Renal Function after Living Donor Liver Transplantation
- (株)癌と化学療法社, 2011年11月, 癌と化学療法, 38(12) (12), 2030 - 2032, 日本語
- (株)癌と化学療法社, 2011年11月, 癌と化学療法, 38(12) (12), 2065 - 2067, 日本語
- 2011年10月, HEPATOLOGY, 54, 681A - 681A, 英語RENAL FUNCTION DETERIORATES AFTER LIVING DONOR LIVER TRANSPLANTATION; HOW TO PREDICT CHRONIC DYSFUNCTION?
- 2011年10月, HEPATOLOGY, 54, 1385A - 1386A, 英語PERCUTANEOUS ISOLATED HEPATIC PERFUSION (PIHP) FOR ADVANCED HEPATOCELLULAR CARCINOMA: TWO DECADES EXPERIENCE OF KOBE PROGRAM
- APA/JPS/CAP/IAP 2024, 2024年12月, 日本語, 国内会議Comprehensive analysis of altered lipid and amino acid metabolism in patients undergoing pancreatoduodenectomy口頭発表（一般）
- 第41回近畿肝移植検討会, 2024年12月, 日本語, 国内会議家族性βリポ蛋白血症による非代償性硬変に対し脳死肝移植を行った一例口頭発表（一般）
- 第37回日本内視鏡外科学会総会（JSES2024）, 2024年12月, 日本語, 国内会議胆嚢摘出既往のある再肝切除症例における腹腔鏡アプローチの有用性に関する検討口頭発表（一般）
- 第37回日本内視鏡外科学会総会（JSES2024）, 2024年12月, 日本語, 国内会議糖原病Ia型に併発した多発肝細胞癌線腫の1切除例口頭発表（一般）
- 第37回日本内視鏡外科学会総会（JSES2024）, 2024年12月, 日本語, 国内会議Fontan循環における腹腔鏡下肝切除術の経験口頭発表（一般）
- 第37回日本内視鏡外科学会総会（JSES2024）, 2024年12月, 日本語, 国内会議3Dシミュレーション画像は真のリアルタイムナビゲーションになっているか？シンポジウム・ワークショップパネル（指名）
- 第37回日本内視鏡外科学会総会（JSES2024）, 2024年12月, 日本語, 国内会議膵癌に対する腹腔鏡下膵体尾部切除術の短期・長期成績に関する検討シンポジウム・ワークショップパネル（指名）
- 第37回日本内視鏡外科学会総会（JSES2024）, 2024年12月, 日本語, 国内会議40歳肝胆膵外科医の腹腔鏡下膵切除の実際シンポジウム・ワークショップパネル（指名）
- 第37回日本内視鏡外科学会総会（JSES2024）, 2024年12月, 日本語, 国内会議ロボット支援下膵切除導入の経験とフィードバックシンポジウム・ワークショップパネル（指名）
- 第86回日本臨床外科学会総会, 2024年11月, 日本語, 国内会議進行肝細胞癌に対するアテゾリズマブ・ベバシズマブ併用療法によるcancer free/drug freeを目指した治療戦略シンポジウム・ワークショップパネル（指名）
- 第86回日本臨床外科学会総会, 2024年11月, 日本語, 国内会議腹腔鏡下肝切除技術認定取得への道シンポジウム・ワークショップパネル（指名）
- 第18回肝臓内視鏡外科研究会, 2024年11月, 日本語, 国内会議Clamp crushing法を駆使した腹腔鏡下肝切除シンポジウム・ワークショップパネル（指名）
- 第66回日本消化器病学会大会（JDDW2024）, 2024年10月, 英語, 国内会議Postoperative complications assessed by the comprehensive complication index (CCI) are associated with early recurrence after curative resection for biliary tract cancerポスター発表
- 第22回日本消化器外科学会（JDDW2024）, 2024年10月, 英語, 国内会議Clinical Significance of Laparoscopic 0-mm Margin Liver Resection for Vascular in Patients with Hepatocellular Carcinomaポスター発表
- 第22回日本消化器外科学会（JDDW2024）, 2024年10月, 日本語, 国内会議吸収性スペーサー併用粒子線治療後に局所再発した後腹膜平滑筋肉腫に対して2回目の吸収性スペーサー留置術および粒子線治療を行った1例ポスター発表
- 第22回日本消化器外科学会（JDDW2024）, 2024年10月, 日本語, 国内会議左側門脈圧亢進症に対する門脈ステントの有用性についてポスター発表
- 第22回日本消化器外科学会（JDDW2024）, 2024年10月, 日本語, 国内会議胆道癌術後S-1術後補助療法施行例におけるGLIM基準の予後因子としての有用性に関する検討ポスター発表
- 第22回日本消化器外科学会（JDDW2024）, 2024年10月, 日本語, 国内会議胆道癌に対するS-1術後補助化学療法と術後早期再発との関連ポスター発表
- 第22回日本消化器外科学会（JDDW2024）, 2024年10月, 日本語, 国内会議膵頭十二指腸切除術後の血中必須脂肪酸の推移およびPD後NAFLDとの関係ポスター発表
- 第22回日本消化器外科学会（JDDW2024）, 2024年10月, 日本語, 国内会議進行肝細胞癌に対する薬物療法を中心とした集学的治療ポスター発表
- 第22回日本消化器外科学会（JDDW2024）, 2024年10月, 日本語, 国内会議膵癌術後再発病変に対する外科的切除は予後延長に寄与するのかポスター発表
- 第22回日本消化器外科学会（JDDW2024）, 2024年10月, 日本語, 国内会議主要脈管近接腫瘍に対する腹腔鏡下Parenchymal-sparing hepatectomyポスター発表
- 第22回日本消化器外科学会（JDDW2024）, 2024年10月, 日本語, 国内会議肝細胞癌症例における肝切除術後胆汁漏の予後への影響についての検討ポスター発表
- 第58回近畿肝癌談話会, 2024年10月, 日本語, 国内会議腫瘍学的切除可能性分類定義に基づいた肝切除・薬物療法成績の検討口頭発表（一般）
- ILLS2024, 2024年10月, 英語, 国際会議Laparoscopic anatomic liver resection of segment 7 guided by 3D simulation and ICG fluorescence imagingシンポジウム・ワークショップパネル（公募）
- 第60回日本移植学会総会, 2024年09月, 日本語, 国内会議家族性低βリポ蛋白血症に伴う非代償性肝硬変に対して脳死肝移植術を施行した1例ポスター発表
- 第60回日本移植学会総会, 2024年09月, 日本語, 国内会議肝移植後 MASLD 発症を予測する因子に関する観察研究ポスター発表
- 第60回日本移植学会総会, 2024年09月, 日本語, 国内会議当院における high MELD score 肝不全に対する肝移植の治療成績シンポジウム・ワークショップパネル（公募）
- 第47回日本膵・胆管合流異常研究会, 2024年09月, 日本語, 国内会議膵・胆管合流異常に合併した2型 IPNB に相当する胆嚢内乳頭状腫瘍の1例口頭発表（一般）
- ELSA2024, 2024年08月, 英語, 国内会議Optimal cutoff values of drain amylase for predicting pancreatic fistula are different between open and laparoscopic distal pancreatectomy口頭発表（一般）
- 第30回日本肝がん分子標的治療研究会, 2024年07月, 日本語, 国内会議デュルバルマブ・トレメリムマブ併用療法導入初期の治療成績から薬物療法の最適な se-quence を考える口頭発表（一般）
- 第55回日本膵臓学会大会, 2024年07月, 日本語, 国内会議局所進行切除不能膵癌に対するスペーサー留置術後の陽子線治療の成績と展望口頭発表（一般）
- 第55回日本膵臓学会大会, 2024年07月, 日本語, 国内会議膵癌に対する膵切除術における膵断端の癌遺残に関する検討ポスター発表
- The 14th Asia-Pacific Primary Liver Cancer Expert Meeting 2024 (APPLE), 2024年07月, 英語, 国際会議Textbook outcomes in initial liver resection for hepatocellular carcinoma: a study with malnutrition grade by the GLIM criteria.ポスター発表
- The 14th Asia-Pacific Primary Liver Cancer Expert Meeting 2024 (APPLE), 2024年07月, 英語, 国際会議Clinical significance of hepatectomy for Hepatocellular Carcinoma Associated with Lymph Node and/or Distant Metastasesポスター発表
- The 14th Asia-Pacific Primary Liver Cancer Expert Meeting 2024 (APPLE), 2024年07月, 英語, 国際会議Laparoscopic Liver Resection after Pancreaticoduodenectomyポスター発表
- 第79回日本消化器外科学会総会, 2024年07月, 日本語, 国内会議当科における吸収性スペーサー留置術 48 例の検討口頭発表（一般）
- 第79回日本消化器外科学会総会, 2024年07月, 日本語, 国内会議GLIM 基準でみる肝細胞癌に対する肝切除の Textbook outcome口頭発表（一般）
- 第79回日本消化器外科学会総会, 2024年07月, 日本語, 国内会議先天性胆道拡張症 術後合併症の検討口頭発表（一般）
- 第79回日本消化器外科学会総会, 2024年07月, 日本語, 国内会議進行肝細胞癌に対する cancer free, drug free を目指した治療戦略の意義口頭発表（一般）
- 第79回日本消化器外科学会総会, 2024年07月, 日本語, 国内会議肝細胞癌における腹腔鏡下 SM0 肝切除の有用性に関する検討口頭発表（一般）
- 第79回日本消化器外科学会総会, 2024年07月, 日本語, 国内会議切除後再発リスク分類と大腸癌肝転移の集学的治療戦略口頭発表（一般）
- 第79回日本消化器外科学会総会, 2024年07月, 日本語, 国内会議消化器外科医夫婦がキャリア形成を続けるためにした工夫口頭発表（一般）
- 第79回日本消化器外科学会総会, 2024年07月, 日本語, 国内会議肝細胞癌に対する幕内基準外肝右葉切除後における術後肝不全発症の危険因子の検討口頭発表（一般）
- 第79回日本消化器外科学会総会, 2024年07月, 日本語, 国内会議術後難治性胆管狭窄症例に対する治療経験口頭発表（一般）
- 第79回日本消化器外科学会総会, 2024年07月, 日本語, 国内会議当科における進行胆道癌に対する conversion surgery の経験口頭発表（一般）
- 第79回日本消化器外科学会総会, 2024年07月, 日本語, 国内会議胆嚢摘出術既往のある再肝切除症例における開腹，腹腔鏡アプローチの手術成績の比較口頭発表（一般）
- 第60回日本肝癌研究会, 2024年07月, 日本語, 国内会議進行肝細胞癌に対するアテゾリズマブ・ベバシズマブ療法による cancer free、 drug free を目指した治療戦略口頭発表（一般）
- 第60回日本肝癌研究会, 2024年07月, 日本語, 国内会議肝細胞癌における肝切除術後胆汁漏関連因子の予後への影響に関する検討口頭発表（一般）
- 第60回日本肝癌研究会, 2024年07月, 日本語, 国内会議当科における全腫瘍体積を用いた大腸癌肝転移の治療戦略シンポジウム・ワークショップパネル（公募）
- 第60回日本肝癌研究会, 2024年07月, 日本語, 国内会議腫瘍学的切除可能性分類定義に基づいた肝切除・薬物療法成績の検討シンポジウム・ワークショップパネル（公募）
- 第36回日本肝胆膵外科学会・学術集会, 2024年06月, 英語, 国内会議Comparison of laparoscopic partial liver resection for the superior and the inferior areas of segment 4口頭発表（一般）
- 第36回日本肝胆膵外科学会・学術集会, 2024年06月, 英語, 国内会議Efficacy of the bile leak test using contrast-enhanced intraoperative ultrasonic cholangiography in liver resection: A prospective study口頭発表（一般）
- 第36回日本肝胆膵外科学会・学術集会, 2024年06月, 英語, 国内会議Short- and long-term outcomes after pancreatectomy for pancreatic cancer in octogenarianシンポジウム・ワークショップパネル（公募）
- 第36回日本肝胆膵外科学会・学術集会, 2024年06月, 英語, 国内会議Clinical significance of hepatectomy for hepatocellular carcinoma associated with lymph node and/ or distant metastasesシンポジウム・ワークショップパネル（公募）
- 第36回日本肝胆膵外科学会・学術集会, 2024年06月, 英語, 国内会議Treatment outcomes of hepatectomy and systemic chemotherapy based on the oncological criteria of resectabilityシンポジウム・ワークショップパネル（公募）
- 第46回日本癌局所療法研究会, 2024年06月, 日本語, 国内会議腹腔鏡下膵頭十二指腸切除術で R0 手術となった胆管原発神経内分泌癌の1切除例口頭発表（一般）
- 第60回日本肝臓学会総会, 2024年06月, 日本語, 国内会議デュルバルマブ・トレメリムマブ併用療法導入初期の治療成績口頭発表（一般）
- 第60回日本肝臓学会総会, 2024年06月, 日本語, 国内会議切除不能肝細胞癌に対するアテゾリズマブ/ベバシズマブ併用療法の治療効果と全腫瘍体積の関連性についての検討口頭発表（一般）
- 第60回日本肝臓学会総会, 2024年06月, 日本語, 国内会議肝切除後患者に対するアテゾリズマブ・ベバシズマブ併用療法の治療効果と安全性口頭発表（一般）
- 第60回日本肝臓学会総会, 2024年06月, 日本語, 国内会議腫瘍学的切除可能性分類定義に基づいた肝切除・薬物療法成績の検討口頭発表（一般）
- EAES2024, 2024年06月, 英語, 国際会議Laparoscopic SM0 liver resection for hepatocellular carcinoma adjacent to the hepatic hilumポスター発表
- 第42回日本肝移植学会学術集会, 2024年06月, 日本語, 国内会議当施設の脳死ドナー肝摘出手技習得における Cadaver Surgical Training の有用性シンポジウム・ワークショップパネル（公募）
- 第42回日本肝移植学会学術集会, 2024年06月, 日本語, 国内会議肝移植後の MASLD 発症を予測する因子に関する検討口頭発表（招待・特別）
- 第42回日本肝移植学会学術集会, 2024年06月, 日本語, 国内会議当院の脳死肝移植における Japan Risk Index の検討口頭発表（一般）
- 第110回日本消化器病学会総会, 2024年05月, 日本語, 国内会議大腸癌肝転移におけるRAS遺伝子情報と肝転移巣局在の関連性口頭発表（一般）
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議当科における吸収性スペーサー留置術 45 例の検討ポスター発表
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議胆道癌術後 S-1 術後補助療法施行例における GLIM 基準の予後因子としての有用性に関する検討ポスター発表
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議当院における肝 S8 背側/腹側領域に対する腹腔鏡下肝部分切除術の手術成績ポスター発表
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議胆道癌における再発時期と再発様式についての検討ポスター発表
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議進行肝細胞癌における腫瘍肉眼形態とアテゾリズマブ・ベバシズマブ併用療法の治療効果に関する検討ポスター発表
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議肝切除における術中超音波胆道造影法を併用したリークテストの有用性ポスター発表
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議外科医が長く働き続けられるための当院での取り組みポスター発表
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議肝門部胆管癌における術後肝不全・難治性腹水ポスター発表
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議大腸癌肝転移における切除後再発リスク分類と集学的治療戦略ポスター発表
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議肝細胞癌に対する肝右葉切除後における術後肝不全発症の危険因子の検討ポスター発表
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議肥満症例での肝 S7 切除における腹腔鏡下アプローチのメリットについてポスター発表
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議高齢遠位胆管癌患者に対する高難度手術成績の検討ポスター発表
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議進行胆道癌に対する Conversion surgeryポスター発表
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議胆道癌に対する膵頭十二指腸切除術における GLIM 基準低栄養が術後合併症へ与える影響の検討口頭発表（一般）
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議膵頭十二指腸切除術後外分泌不全に対する治療バイオマーカーの探索口頭発表（一般）
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議開腹および腹腔鏡下膵体尾部切除のドレーンアミラーゼ値による適切なドレーン管理の検討口頭発表（一般）
- 第124回日本外科学会定期学術集会, 2024年04月, 日本語, 国内会議肝細胞癌薬物療法における sequential 局所治療の位置づけシンポジウム・ワークショップパネル（公募）
- The 33rd Annual Meeting the Asian Pacific Association for the Study of the Liver (APASL2024), 2024年03月, 日本語, 国際会議Utility of ALBI grade for predicting prognoses in patients who underwent repeat hepatectomyポスター発表
- The 33rd Annual Meeting the Asian Pacific Association for the Study of the Liver (APASL2024), 2024年03月, 日本語, 国際会議Multidisciplinary treatment strategy for macroscopic portal vein tumor thrombusポスター発表
- The 33rd Annual Meeting the Asian Pacific Association for the Study of the Liver (APASL2024), 2024年03月, 日本語, 国際会議Association between tumor morphology and efficacy of atezolizumab plus bevacizumab for advanced HCC口頭発表（一般）
- The 33rd Annual Meeting the Asian Pacific Association for the Study of the Liver (APASL2024), 2024年03月, 日本語, 国際会議A comparative study of laparoscopic liver resection for the segment 4 superior and inferior area口頭発表（一般）
- The 33rd Annual Meeting the Asian Pacific Association for the Study of the Liver (APASL2024), 2024年03月, 日本語, 国際会議The Efficacy of Total Tumor Volume in Patients with Colorectal Liver Metastases口頭発表（一般）
- 第10回神戸肝胆膵外科ビデオクリニック, 2024年03月, 日本語, 国内会議司会その他
- 第51回近畿肝臓外科研究会, 2024年02月, 日本語, 国内会議主要脈管近接腫瘍に対する腹腔鏡下肝切除口頭発表（一般）
- 第56回制癌剤適応研究会, 2024年02月, 日本語, 国内会議GC+ デュルバルマブ療法が奏功し根治的肝切除術を施行し得た胆嚢癌術後肝転移再発の 1 例口頭発表（一般）
- 日本消化器病学会近畿支部第120回例会, 2024年01月, 日本語, 国内会議胆道再建既往の肝切除症例における術後感染性合併症口頭発表（一般）
- 日本消化器病学会近畿支部第120回例会, 2024年01月, 日本語, 国内会議GLIM基準低栄養は胆道癌に対する膵頭十二指腸切除術後合併症リスクを増加させる口頭発表（一般）
- 第45回日本肝臓学会西部会, 2023年12月, 日本語, 国内会議肝細胞癌再発に対してラムシルマブ長期投与が可能であった1例口頭発表（一般）
- 第45回日本肝臓学会西部会, 2023年12月, 日本語, 国内会議肝予備能不良な肝細胞癌に対して吸収性スペーサー留置後に陽子線治療を施行し腫瘍制御が得られた1例口頭発表（一般）
- 第85回日本臨床外科学会総会, 2023年11月, 日本語, 国内会議アテゾリズマブ＋ベバシズマブ併用療法によりコンバージョン手術を施行し得た切除不能肝 細胞癌の2例ポスター発表
- 第85回日本臨床外科学会総会, 2023年11月, 日本語, 国内会議吸収性スペーサー留置術35例の検討ポスター発表
- 第85回日本臨床外科学会総会, 2023年11月, 日本語, 国内会議肝細胞癌薬物療法を外科医が行う意義口頭発表（一般）
- 第85回日本臨床外科学会総会, 2023年11月, 日本語, 国内会議肝細胞癌薬物療法後コンバージョン治療の可能性シンポジウム・ワークショップパネル（公募）
- 第17回肝臓内視鏡外科研究会, 2023年11月, 日本語, 国内会議腹腔鏡下肝 S8 部分切除術の手術手技の肝（キモ）～ S8 腹側・背側領域の比較を含めて～シンポジウム・ワークショップパネル（公募）
- 第65回日本消化器病学会大会（JDDW2023), 2023年11月, 日本語, 国内会議胆道癌における再発時期と再発形式の検討ポスター発表
- 第21回日本消化器外科学会大会（JDDW2023）, 2023年11月, 日本語, 国内会議肝外胆管癌における術前骨格筋量減少の術後早期再発への影響ポスター発表
- 第21回日本消化器外科学会大会（JDDW2023）, 2023年11月, 日本語, 国内会議The feasibility of laparoscopic liver resection with 0-mm surgical margin for hepatocellular carcinomaポスター発表
- 第21回日本消化器外科学会大会（JDDW2023）, 2023年11月, 日本語, 国内会議吸収性スペーサー留置術33例の検討ポスター発表
- 第21回日本消化器外科学会大会（JDDW2023）, 2023年11月, 日本語, 国内会議肝門部胆管癌術後の術後胆汁漏の検討ポスター発表
- 第21回日本消化器外科学会大会（JDDW2023）, 2023年11月, 日本語, 国内会議肝切除術後の門脈血栓症に対するエドキサバンの治療成績ポスター発表
- 第21回日本消化器外科学会大会（JDDW2023）, 2023年11月, 日本語, 国内会議胆管非拡張型膵・胆管合流異常に対する胆嚢摘出後に胆管径は変化するかポスター発表
- 第21回日本消化器外科学会大会（JDDW2023）, 2023年11月, 日本語, 国内会議膵癌術後再発に対する治療戦略の現状と展望ポスター発表
- 第21回日本消化器外科学会大会（JDDW2023）, 2023年11月, 日本語, 国内会議初回肝切除への腹腔鏡アプローチ適応による再肝切除時のメリットについてポスター発表
- 第21回日本消化器外科学会大会（JDDW2023）, 2023年11月, 日本語, 国内会議当院における術後胆管狭窄症例に対する対応と検討ポスター発表
- 第21回日本消化器外科学会大会（JDDW2023）, 2023年11月, 日本語, 国内会議根治を目指した肝細胞癌薬物療法と局所療法のコンビネーションポスター発表
- 第21回日本消化器外科学会大会（JDDW2023）, 2023年11月, 日本語, 国内会議肝外胆管癌切除後S-1補助化学療法例におけるGLIM基準の有用性に関する検討ポスター発表
- IASGO-CME, 2023年11月, 英語, 国際会議Association between tumor morphology and efficacy of atezolizumab plus bevacizumab for advanced hepatocellular carcinomaポスター発表
- 7th Kansai-Yeungnam HBP Surgeons Meeting, 2023年10月, 英語, 国際会議Risk Factors for Recurrence of Cholangitis After Pancreaticoduodenectomy and Comparison of Stents in Hepaticojejunostomyポスター発表
- 第59回日本移植学会総会, 2023年09月, 日本語, 国内会議肝移植後の経時的な体重変化を予測する因子についての観察研究ポスター発表
- 第59回日本移植学会総会, 2023年09月, 日本語, 国内会議脳死肝移植・肝グラフト採取術手技習得における Cadaver Surgical Training の有用性口頭発表（一般）
- 第59回日本移植学会総会, 2023年09月, 日本語, 国内会議次世代継承,肝移植のススメシンポジウム・ワークショップパネル（公募）
- 第59回日本移植学会総会, 2023年09月, 日本語, 国内会議当施設における RTC 育成の現状と課題シンポジウム・ワークショップパネル（公募）
- 第59回日本胆道学会学術集会, 2023年09月, 日本語, 国内会議胆道癌術後補助化学療法施行例における早期再発のリスク因子の検討ポスター発表
- 第59回日本胆道学会学術集会, 2023年09月, 日本語, 国内会議当科で経験した無石性胆嚢炎症例の臨床像ポスター発表
- 第59回日本胆道学会学術集会, 2023年09月, 日本語, 国内会議胆道癌に対するS-1術後補助化学療法と再発時期の関連ポスター発表
- 4th World Congress of International Laparoscopic liver Society（ILLS）, 2023年09月, 英語, 国際会議A comparative study of laparo-scopic liver resection for the segment 8 dorsal and ventral area口頭発表（一般）
- 4th World Congress of International Laparoscopic liver Society（ILLS）, 2023年09月, 英語, 国際会議Short-term impact of laparoscopic liver resection with 0-mm surgical margin for HCC口頭発表（一般）
- 4th World Congress of International Laparoscopic liver Society（ILLS）, 2023年09月, 英語, 国際会議Acceptability of Laparoscopic Liver Resection of Segment I: A Retrospective Study口頭発表（一般）
- 4th World Congress of International Laparoscopic liver Society（ILLS）, 2023年09月, 英語, 国際会議Laparoscopic segmentectomy2 versus left lateral sectionecto-my for liver tumors in segment2口頭発表（一般）
- 45th ESPEN Congress, 2023年09月, 英語, 国際会議Impact of malnutrition diagnosed by the GLIM criteria on postoperative complications after pancreaticoduodenectomy for biliary tract cancerポスター発表
- 45th ESPEN Congress, 2023年09月, 英語, 国際会議Impact of malnutrition diagnosed by the GLIM criteria on outcome of elderly patients with hepatocellular carcinoma after liver resectionポスター発表
- 第46回日本膵・胆管合流異常研究会, 2023年09月, 日本語, 国内会議膵・胆管合流異常に発生した膵管内乳頭粘液性腺癌の1切除例口頭発表（招待・特別）
- 第57回近畿肝癌談話会, 2023年08月, 日本語, 国内会議根治を目指した肝細胞癌薬物療法シークエンス口頭発表（一般）
- 第59回日本肝癌研究会, 2023年07月, 日本語, 国内会議根治を目指した肝細胞癌薬物療法シークエンス口頭発表（一般）
- 第59回日本肝癌研究会, 2023年07月, 日本語, 国内会議肝細胞癌肉眼分類とアテゾリズマブ・ベバシズマブ併用療法の治療効果に関する検討シンポジウム・ワークショップパネル（公募）
- 第54回日本膵臓学会大会, 2023年07月, 日本語, 国内会議高齢者に対する膵全摘, 残膵全摘の短期・長期成績についてシンポジウム・ワークショップパネル（公募）
- 第78回日本消化器外科学会総会, 2023年07月, 日本語, 国内会議門脈腫瘍栓を伴う肝細胞癌患者における EOB-MRI を用いた機能的残肝容積測定による術後肝不全予測法口頭発表（一般）
- 第78回日本消化器外科学会総会, 2023年07月, 日本語, 国内会議大腸癌肝転移における全腫瘍体積を用いた適切な治療戦略に関する検討口頭発表（一般）
- 第78回日本消化器外科学会総会, 2023年07月, 日本語, 国内会議切除後再発リスクから見た大腸癌肝転移の治療戦略口頭発表（一般）
- 第78回日本消化器外科学会総会, 2023年07月, 日本語, 国内会議肝細胞癌患者における肝切除後肝不全が中長期的肝機能と再発に与える影響口頭発表（一般）
- 第78回日本消化器外科学会総会, 2023年07月, 日本語, 国内会議内側アプローチによる腹腔鏡下 Spiegel 葉切除口頭発表（一般）
- 第78回日本消化器外科学会総会, 2023年07月, 日本語, 国内会議脳死肝移植・肝グラフト採取術手技習得のための Cadaver Surgical Training の有用性口頭発表（一般）
- 第78回日本消化器外科学会総会, 2023年07月, 日本語, 国内会議Vp3/4 肝細胞癌に対する集学的治療シンポジウム・ワークショップパネル（公募）
- 第35回日本肝胆膵外科学会学術集会, 2023年06月, 日本語, 国内会議A study for infectious complication of hepatectomies in patients with preexisting bilioenteric anastomosisポスター発表
- 第35回日本肝胆膵外科学会学術集会, 2023年06月, 日本語, 国内会議Association between morphologic appearance in CT/MRI and efficacy of atezolizumab plus bevacizumab for advanced hepatocellular carcinomaポスター発表
- 第35回日本肝胆膵外科学会学術集会, 2023年06月, 日本語, 国内会議Intracholecystic papillary neoplasm (ICPN) with pancreaticobiliary maljunction (PBM): Comparison with normal gallbladder cancer with PBMポスター発表
- 第35回日本肝胆膵外科学会学術集会, 2023年06月, 日本語, 国内会議Successful biliary drainage using hybrid EUS-BD for stricture of choledochojejunostomyポスター発表
- 第35回日本肝胆膵外科学会学術集会, 2023年06月, 日本語, 国内会議Intended destination for a board certified surgeon under 45口頭発表（一般）
- 第35回日本肝胆膵外科学会学術集会, 2023年06月, 日本語, 国内会議Prognostic significance of malnutrition diagnosed by the GLIM criteria for resected extrahepatic cholangiocarcinoma: A single-center retrospective study口頭発表（一般）
- 第35回日本肝胆膵外科学会学術集会, 2023年06月, 日本語, 国内会議The optimal treatment strategy of therapeutic intervention using total tumor volume in patients with colorectal liver metastases口頭発表（一般）
- 第35回日本肝胆膵外科学会学術集会, 2023年06月, 日本語, 国内会議Improvement in stapler pancreatic transection to reduce pancreatic fistula after laparoscopic distal pancreatectomy: twelve-year experience at a single high-volume center口頭発表（一般）
- 第35回日本肝胆膵外科学会学術集会, 2023年06月, 日本語, 国内会議Anterior approach for open rigththepatectomy for huge hepatocellular carcinomaシンポジウム・ワークショップパネル（公募）
- 第35回日本肝胆膵外科学会学術集会, 2023年06月, 日本語, 国内会議Our surgical technique of vascular dissection and resection for locally advanced pancreatic cancerシンポジウム・ワークショップパネル（公募）
- 第35回日本肝胆膵外科学会学術集会, 2023年06月, 日本語, 国内会議Legitimacy of systemic chemotherapy for unresectable hepatocellular carcinoma aiming conversion hepatectomyシンポジウム・ワークショップパネル（公募）
- The 31st International Congress of the European Association for Endoscopic Surgery (EAES), 2023年06月, 英語, 国際会議Laparoscopic liver resection after pancreaticoduodenectomy口頭発表（一般）
- 第59回日本肝臓学会総会, 2023年06月, 日本語, 国内会議切除不能肝内胆管癌に対する粒子線治療の成績口頭発表（一般）
- 第59回日本肝臓学会総会, 2023年06月, 日本語, 国内会議肝細胞癌肉眼分類とアテゾリズマブ・ベバシズマブ併用療法の治療効果に関する検討口頭発表（一般）
- 第59回日本肝臓学会総会, 2023年06月, 日本語, 国内会議高度脈管侵襲陽性肝細胞癌に対する集学的治療口頭発表（一般）
- 第68回国際外科学会日本部会総会, 2023年06月, 日本語, 国内会議Investigation of the relationship between complications after pancreaticoduodenectomy for distal cholangiocarcinoma and malnutrition diagnosed by the GLIM criteria口頭発表（一般）
- 第45回日本癌局所療法研究会, 2023年06月, 日本語, 国内会議腹腔動脈狭窄を伴う十二指腸乳頭部癌に対し膵頭十二指腸切除術を施行した１例口頭発表（一般）
- 第41回日本肝移植学会学術集会, 2023年06月, 日本語, 国内会議脳死肝移植に初めて参加した経験から得られた移植医療に対する抱負口頭発表（一般）
- 第41回日本肝移植学会学術集会, 2023年06月, 日本語, 国内会議COVID-19により変貌を遂げた急性肝不全に対する移植医療シンポジウム・ワークショップパネル（公募）
- 第41回日本肝移植学会学術集会, 2023年06月, 日本語, 国内会議当科における MELD スコア制導入後の脳死肝移植希望登録患者に関する検討シンポジウム・ワークショップパネル（公募）
- ILTS2023, 2023年05月, 英語, 国際会議The factors of predicting over-time weight increase after liver transplantationポスター発表
- ILTS2023, 2023年05月, 英語, 国際会議Indication of liver transplantation in the treatment of newly categorized acute-on-chronic liver failure in Japanポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議肝外胆管癌切除後の早期再発予測におけるGLIM基準の有用性ポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議大腸癌肝転移における予後予測因子としての全腫瘍体積の有用性と，適切な化学療法導入時期に関する観察研究ポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議当科における吸収性スペーサー留置術22例の臨床経過ポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議術前化学療法後に切除を施行したBR-A膵癌，UR-LA膵癌における早期再発risk因子の検討ポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議胆道癌における術後静脈血栓症と血漿Dダイマーの関連性の検討ポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議当科における非吸収性スペーサー留置術の治療成績と今後の課題ポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議術前NLR値と胆嚢癌の予後との関連ポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議肝細胞癌切除症例におけるGLIM基準と予後の関連ポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議十二指腸乳頭部癌におけるC-reactive protein to albumin ratio（CAR）の予後への影響ポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議右肝葉切除を施行した肝門部領域胆管癌の再考；左側からの切除の可能性ポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議治療成績から見た大腸癌肝転移における切除可能性分類と治療戦略ポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議肝門部領域胆管癌に対する術前門脈塞栓術施行例の検討ポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議肝移植後長期成績向上のために，何が必要かポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議局所進行膵癌に対する外科治療ポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議肝外胆管癌切除後予後因子としてのGLIM基準の有用性に関する検討ポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議ロボット支援下膵体尾部切除導入期に直面する技術的問題点ポスター発表
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議胆道癌に対するS-1術後補助化学療法と早期再発の関連口頭発表（一般）
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議Under 40外科医が専門医取得の次に目指すものシンポジウム・ワークショップパネル（公募）
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議進行肝細胞癌に対するConversion surgeryの妥当性シンポジウム・ワークショップパネル（公募）
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議初回再発形式からみる表在性肝細胞癌に対する非系統的切除術の妥当性に関する検討シンポジウム・ワークショップパネル（公募）
- 第123回日本外科学会定期学術集会, 2023年04月, 日本語, 国内会議膵癌患者における術前低栄養の評価とその臨床的役割シンポジウム・ワークショップパネル（公募）
- 第8回神戸肝胆膵外科ビデオクリニック, 2023年04月, 日本語, 国内会議司会（一般演題）その他
- 第109回日本消化器病学会総会, 2023年04月, 日本語, 国内会議食道胃静脈瘤に対するHassab手術が術後肝機能に与える影響についての検討口頭発表（一般）
- 第109回日本消化器病学会総会, 2023年04月, 日本語, 国内会議アルコール性肝硬変に対する肝移植医療の現状と課題口頭発表（一般）
- 第109回日本消化器病学会総会, 2023年04月, 日本語, 国内会議術前骨格筋量減少が肝外胆管癌切除後の長期予後に与える影響に関する観察研究口頭発表（一般）
- 第109回日本消化器病学会総会, 2023年04月, 日本語, 国内会議進行肝細胞癌薬物療法における転移部位別奏効率の検討口頭発表（一般）
- 第109回日本消化器病学会総会, 2023年04月, 日本語, 国内会議肝胆膵領域におけるAIを用いた手術支援技術の現状と展望口頭発表（一般）
- 第59回日本腹部救急医学会総会, 2023年03月, 日本語, 国内会議当科における無石性胆嚢炎症例の手術成績口頭発表（一般）
- 第50回近畿肝臓外科研究会, 2023年01月, 日本語, 国内会議当科肝臓外科における術中ナビゲーションの現状と展望口頭発表（一般）
- 第39回近畿肝移植検討会, 2022年12月, 日本語, 国内会議脳死肝移植登録待機中管理に難渋した一例口頭発表（一般）
- Asian-Pacific Congress of Robotic Laparoscopic Surgery 2022 (ACRLS 2022), 2022年12月, 英語, 国際会議Laparoscopic anatomical resection of segment 2 by Glissonean approach口頭発表（一般）
- 第35回日本内視鏡外科学会総会, 2022年12月, 日本語, 国内会議当院における腹腔鏡下膵頭十二指腸切除の導入口頭発表（一般）
- 第35回日本内視鏡外科学会総会, 2022年12月, 日本語, 国内会議ロボット支援膵切除時代における技術認定制度の役割と問題点シンポジウム・ワークショップパネル（公募）
- 第35回日本内視鏡外科学会総会, 2022年12月, 日本語, 国内会議当施設での亜区域切除のアプローチ法シンポジウム・ワークショップパネル（公募）
- Transplantation Science Symposium(TSS) Asian Regional Meeting 2022, 2022年11月, 英語, 国際会議The Factors of Predicting Over-Time Weight Increase After Liver Transplantation口頭発表（一般）
- 第44回日本肝臓学会東部会, 2022年11月, 日本語, 国内会議粒子線治療適応拡大を可能とする新規素材吸収性スペーサーの開発と臨床応用した肝細胞癌の 1 例口頭発表（一般）
- 第44回日本肝臓学会東部会, 2022年11月, 日本語, 国内会議肝S8領域に生じた肝細胞癌に対する腹腔鏡下肝切除術の有効性に関する検討口頭発表（一般）
- 第44回日本肝臓学会東部会, 2022年11月, 日本語, 国内会議初回再発形式からみる肝細胞癌の腫瘍位置と初回再発形式に関する検討口頭発表（一般）
- 第35回日本外科感染症学会総会学術集会, 2022年11月, 日本語, 国内会議胆道癌に対する術前胆汁返還の SSI に対する意義シンポジウム・ワークショップパネル（公募）
- JDDDW2022, 2022年10月, 日本語, 国内会議The usefulness of total tumor volume as a prognostic factor with colorectal cancer liver metastasesポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議肝S8病変に対する腹腔鏡下肝切除術適応の有効性ポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議肝切除後の術後静脈血栓塞栓症の発症における予測スコアの有用性の検討ポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議当科における非吸収性スペーサー留置術の成績と今後の課題ポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議膵頭十二指腸切除術後の早期胆管炎リスク因子の検討ポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議再発形式からみる表在性肝細胞癌に対する非解剖学的切除術の妥当性の検討ポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議初発単発肝細胞癌に対する肝切除と粒子線治療成績の比較検討ポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議胆嚢癌におけるInflammation-based prognostic scoresの予後への影響ポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議血清D-dimer値を用いた膵切除後静脈血栓症予測ポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議食道癌術後の膵癌に対する膵切除6例の検討ポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議肝動脈化学塞栓療法を中心とした膵神経内分泌腫瘍肝転移に対する集学的治療ポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議肝細胞癌に対するmajor hepatectomy後の術後肝不全発症早期予測における術後1日目CRP低値の有用性ポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議肝S7切除における腹腔鏡手術と開腹手術の手術成績の比較ポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議胆管癌の術後早期再発症例の検討ポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議進行肝細胞癌におけるConversion surgeryの妥当性ポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議非乳頭部十二指腸癌に対する手術成績ポスター発表
- 第20回消化器外科学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議腹腔鏡下膵体尾部切除における45mmカートリッジを用いた膵切離ポスター発表
- 第64回消化器病学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議Intermediate HCCに対する集学的アプローチポスター発表
- 第26回肝臓学会大会（JDDW2022）, 2022年10月, 日本語, 国内会議ポストコロナ時代における急性肝不全に対する移植医療ポスター発表
- 第60回癌治療学会学術集会, 2022年10月, 日本語, 国内会議神戸大学における肝癌集学的治療の現状シンポジウム・ワークショップパネル（公募）
- 第58回日本移植学会総会, 2022年10月, 日本語, 国内会議移植後非結核性抗酸菌症治療中にCOVID-19を発症した一例口頭発表（一般）
- 第58回日本移植学会総会, 2022年10月, 日本語, 国内会議コロナ禍における肝移植医療の現状と課題口頭発表（一般）
- 第58回日本移植学会総会, 2022年10月, 日本語, 国内会議移植医療における働き方改革推進の現状と課題口頭発表（一般）
- 第14回日本Acute Care Surgery学会学術集会, 2022年09月, 日本語, 国内会議がん化学療法中の急性胆嚢炎症例の検討ポスター発表
- 日本蛍光ガイド手術研究会第５回学術集会, 2022年09月, 日本語, 国内会議ICG蛍光法を用いた腹腔鏡下肝S2亜区域切除術シンポジウム・ワークショップパネル（公募）
- 第45回日本膵・胆管合流異常研究会, 2022年09月, 日本語, 国内会議胆管非拡張型膵・胆管合流異常に対する胆嚢摘出後の胆管径の変化に関する検討（第2報）口頭発表（一般）
- APASL Oncology 2022, 2022年09月, 英語, 国際会議Hepatic Resection versus Particle Therapy for Single Hepatocellular Carcinoma as An Initial Treatment: A Multicenter Propensity Score Matched Analysisポスター発表
- 第56回近畿肝癌談話会, 2022年08月, 日本語, 国内会議進行肝細胞癌における conversion surgery の妥当性口頭発表（一般）
- 第77回日本消化器外科学会総会, 2022年07月, 日本語, 国内会議大腸癌肝転移における予後予測因子としての全腫瘍体積の有用性口頭発表（一般）
- 第77回日本消化器外科学会総会, 2022年07月, 日本語, 国内会議C型肝炎ウイルスの治療後SVR群，RNA陽性群における肝癌切除例の比較検討口頭発表（一般）
- 第77回日本消化器外科学会総会, 2022年07月, 日本語, 国内会議腹腔鏡下肝S2亜区域切除術の定型化口頭発表（一般）
- 第77回日本消化器外科学会総会, 2022年07月, 日本語, 国内会議肝細胞癌に対する肝右葉切除後の術後肝不全発症早期予測における術後1日目C反応性蛋白低値の有用性口頭発表（一般）
- 第77回日本消化器外科学会総会, 2022年07月, 日本語, 国内会議肝左背側領域における系統的腹腔鏡下肝切除のknack & pitfalls口頭発表（一般）
- 第77回日本消化器外科学会総会, 2022年07月, 日本語, 国内会議Multidisciplinary approach for advanced hepatocellular carcinomaシンポジウム・ワークショップパネル（公募）
- 第77回日本消化器外科学会総会, 2022年07月, 日本語, 国内会議コロナ禍において発展を遂げた肝移植医療の現状と課題シンポジウム・ワークショップパネル（公募）
- 第40回日本肝移植学会学術集会, 2022年07月, 日本語, 国内会議肝移植後の経時的体重変化を予測する因子に関する観察研究口頭発表（一般）
- 第40回日本肝移植学会学術集会, 2022年07月, 日本語, 国内会議当科における MELD スコア制導入後の脳死肝移植希望登録患者に関する検討口頭発表（一般）
- 第40回日本肝移植学会学術集会, 2022年07月, 日本語, 国内会議当施設における脳死下臓器摘出時互助制度の現状と課題シンポジウム・ワークショップパネル（公募）
- 30th International Congress of the European Association for Endoscopic Surgery （EAES2022）, 2022年07月, 英語, 国際会議Standardization of laparoscopic anatomic liver resection of segment 2 by glissonean approach口頭発表（一般）
- 第47回日本外科系連合学会学術集会, 2022年06月, 日本語, 国内会議当科における吸収性スペーサー留置術 15 例の検討口頭発表（一般）
- 第47回日本外科系連合学会学術集会, 2022年06月, 日本語, 国内会議門脈腫瘍栓のみを認めた肝細胞癌に対して集学的治療が奏功した１例口頭発表（一般）
- 第47回日本外科系連合学会学術集会, 2022年06月, 日本語, 国内会議粒子線治療を目的とした仙骨脊索腫に対する吸収性スペーサー留置術の経験口頭発表（招待・特別）
- 第47回日本外科系連合学会学術集会, 2022年06月, 日本語, 国内会議腹部悪性腫瘍に対するネスキープ留置術の外科的経験シンポジウム・ワークショップパネル（公募）
- 第34回日本肝胆膵外科学会・学術集会, 2022年06月, 日本語, 国内会議Impact of Delayed Gastric Emptying After Pancreatoduodenectomy on Postoperative Nutritional Statusポスター発表
- 第34回日本肝胆膵外科学会・学術集会, 2022年06月, 日本語, 国内会議Spontaneous rupture of splenic hilar lymph node metastasis from hepatocellular carcinoma: a rare case reportポスター発表
- 第34回日本肝胆膵外科学会・学術集会, 2022年06月, 日本語, 国内会議Laparoscopic anatomic liver resection of segment 2 based on the anatomical variation of the hepatic veinsポスター発表
- 第34回日本肝胆膵外科学会・学術集会, 2022年06月, 日本語, 国内会議Low levels of C-reactive protein on postoperative day 1 are an early predictor for posthepatectomy liver failure in hepatocellular carcinoma patients undergoing right hepatectomyポスター発表
- 第34回日本肝胆膵外科学会・学術集会, 2022年06月, 日本語, 国内会議Current role of atezolizumab plus bevacizumab therapy in the sequential treatment of unresectable hepatocellular carcinomaポスター発表
- 第34回日本肝胆膵外科学会・学術集会, 2022年06月, 日本語, 国内会議Utility of plasma serum D-dimer for diagnosis of venous thromboembolism after hepatectomyポスター発表
- 第34回日本肝胆膵外科学会・学術集会, 2022年06月, 日本語, 国内会議The usefulness of total tumor volume as a prognostic factor in patients with colorectal cancer liver metastasesシンポジウム・ワークショップパネル（公募）
- 第34回日本肝胆膵外科学会・学術集会, 2022年06月, 日本語, 国内会議Multidisciplinary approach for advanced hepatocellular carcinomaシンポジウム・ワークショップパネル（公募）
- 第58回日本肝臓学会総会, 2022年06月, 日本語, 国内会議HCV関連肝癌切除例におけるDAA治療群とIFN治療群,非SVR群の比較検討ポスター発表
- 第58回日本肝臓学会総会, 2022年06月, 日本語, 国内会議切除不能肝細胞癌に対するレンバチニブの治療成績口頭発表（一般）
- 第58回日本肝臓学会総会, 2022年06月, 日本語, 国内会議肝細胞癌に対する肝切除における予後予測因子としてのサルコペニアの影響に関する観察研究口頭発表（一般）
- 第58回日本肝臓学会総会, 2022年06月, 日本語, 国内会議肝細胞癌に対する major hepatectomy 後1日目のC反応性蛋白低値は術後肝不全発症の早期予測に有用である口頭発表（一般）
- 第191回兵庫県外科医会学術集会, 2022年05月, 日本語, 国内会議横隔膜腹腔側に発生した solitary fibrous tumor の1例口頭発表（一般）
- 第58回日本肝癌研究会, 2022年05月, 日本語, 国内会議肝細胞癌治療における肝切除および粒子線治療に関する比較検討についてシンポジウム・ワークショップパネル（公募）
- 第58回日本肝癌研究会, 2022年05月, 日本語, 国内会議肝臓外科における手術ナビゲーションの現状とその弱点から考える新展開シンポジウム・ワークショップパネル（公募）
- 第58回日本肝癌研究会, 2022年05月, 日本語, 国内会議進行肝細胞癌における Conversion surgery の妥当性シンポジウム・ワークショップパネル（公募）
- 第58回日本肝癌研究会, 2022年05月, 日本語, 国内会議内側アプローチによる腹腔鏡下尾状葉切除シンポジウム・ワークショップパネル（公募）
- 第108回日本消化器病学会総会, 2022年04月, 日本語, 国内会議肝移植後の経時的体重変化を予測する因子に関する検討口頭発表（一般）
- 第108回日本消化器病学会総会, 2022年04月, 日本語, 国内会議高度進行肝細胞癌に対する集学的アプローチ口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議当院における切除不能肝細胞癌に対するレンバチニブの治療成績口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議膵頭十二指腸切除後患者に対するアミノ酸製剤を用いた術後栄養療法の有用性口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議当科における吸収性スペーサー留置の成績と今後の課題口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議当院における術前補助療法後に切除を施行したBR膵癌と conversion 手術を施行した UR-LA 膵臓の治療成績の比較口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議肝胆道癌における肝切除後静脈血栓塞栓症とDダイマーの関連性の検討口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議高齢者胆嚢癌においても外科切除は有用か口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議高度進行肝細胞癌に対し減量肝切除を実施した症例におけるサルコペニアと予後に関する検討口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議膵癌における術前 Rapid Turnover Protein 測定の臨床的役割口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議腹腔鏡下肝 S7 切除の手術成績の検討口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議肝門部領域胆管癌の術後早期再発症例の検討口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議膵切除後血漿 D-dimer の推移と術後静脈血栓症診断における意義口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議大腸癌肝転移における予後予測因子としての全腫瘍体積の有用性に関する検討口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議当院における切除不能肝細胞癌に対するラムシルマブ治療成績の検討口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議膵頭十二指腸切除術後の早期胆管炎リスク因子の検討口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議肝細胞癌の腫瘍位置と初回再発形式に関する検討口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議肝細胞癌における肝右葉切除術後1日目のC反応性蛋白低値は術後肝不全発症の早期予測に有用である口頭発表（一般）
- 第122回日本外科学会定期学術集会, 2022年04月, 日本語, 国内会議解剖学的特徴を活かした腹腔鏡下尾状葉切除口頭発表（一般）
- 15th World Congress of the International Hepato-Pancreato-Biliary Association (IHPBA), 2022年03月, 英語, 国際会議Intraoperative Assessment of the Demarcation Line and Intersegmental/Sectional Planes in Liver Surgeryポスター発表
- SAGES 2022 Annual Meeting, 2022年03月, 英語, 国際会議Laparoscopic anatomic liver resection of segment 2 by glissonean approachポスター発表
- 日本消化器病学会近畿支部第116回例会, 2022年02月, 日本語, 国内会議膵中央切除後に多発残膵再発をきたし残膵全摘術を施行した膵胆道型(pancreatobiliary type）IPMCの1例口頭発表（一般）
- 第38回近畿肝移植検討会, 2021年12月, 日本語, 国内会議新型コロナ感染拡大が肝移植にもたらした影響と問題点口頭発表（一般）
- 第44回日本肝臓学会西部会, 2021年12月, 日本語, 国内会議肝移植後合併症に対する移植時年齢の及ぼす影響に関する検討口頭発表（一般）
- 第44回日本肝臓学会西部会, 2021年12月, 日本語, 国内会議高度進行肝細胞癌に対する減量切除症例におけるサルコペニアの影響について口頭発表（一般）
- 第44回日本肝臓学会西部会, 2021年12月, 日本語, 国内会議進行肝細胞癌に対するアテゾリズマブ・ベバシズマブ併用療法の検討口頭発表（一般）
- 第44回日本肝臓学会西部会, 2021年12月, 日本語, 国内会議肝移植患者におけるグラフトへの脂肪肝発症の現状と課題口頭発表（一般）
- 第34回日本内視鏡外科学会総会, 2021年12月, 日本語, 国内会議Glissoneanアプローチを用いた腹腔鏡下肝S2亜区域切除口頭発表（一般）
- 第34回日本内視鏡外科学会総会, 2021年12月, 日本語, 国内会議腹腔鏡下肝S7切除の手術成績の検討口頭発表（一般）
- 第34回日本内視鏡外科学会総会, 2021年12月, 日本語, 国内会議尾状葉切除における手術手技の工夫シンポジウム・ワークショップパネル（公募）
- 第83回日本臨床外科学会総会, 2021年11月, 日本語, 国内会議肝切除術におけるDemarcation lineとIntersegmental planeナビゲーションシンポジウム・ワークショップパネル（公募）
- 第83回日本臨床外科学会総会, 2021年11月, 日本語, 国内会議コロナ禍において推進すべき肝移植医療の現状と課題シンポジウム・ワークショップパネル（公募）
- 第57回日本胆道学会学術集会, 2021年10月, 日本語, 国内会議総胆管嚢腫に対する胆管切除術後に発症した胆管癌の１例口頭発表（一般）
- 第57回日本胆道学会学術集会, 2021年10月, 日本語, 国内会議胆道癌におけるSystematic inflammation-based scoresの意義口頭発表（一般）
- 第57回日本移植学会総会, 2021年09月, 日本語, 国内会議移植医療における働き方改革の推進シンポジウム・ワークショップパネル（公募）
- 第44回日本膵・胆管合流異常研究会, 2021年09月, 日本語, 国内会議総胆管嚢腫に対する嚢腫胆管切除術後の膵内胆管に発癌を認めた1例口頭発表（一般）
- 第13回日本消化器外科学会大会(JDDW 2015), 2015年10月, 日本語, 国内会議大腸癌肝転移に対する肝切除時期についての検討ポスター発表
- 17th Congress of the European Society for Organ Transplantation (ESOT Brussels 2015), 2015年09月, 英語, 国際会議Incidence of posthepatectomy liver failure as defined by ISGLS among living liver donors口頭発表（一般）
- 14th Congress of the Asian Society of Transplantation (CAST2015), 2015年08月, 英語, 国際会議A case of outflow block requiring metallic stent of inferior vena cava and hepatic vein after orthotopic liver transplantation using piggyback techniqueポスター発表
- 第51回日本肝癌研究会, 2015年07月, 日本語, 国内会議BCLC intermediate stage 肝癌に対する肝切除例の検討シンポジウム・ワークショップパネル（公募）
- 第２７回日本肝胆膵外科学会・学術集会, 2015年06月, 日本語, 国内会議当科における混合型肝癌切除症例20例の検討ポスター発表
- 第２７回日本肝胆膵外科学会・学術集会, 2015年06月, 日本語, 国内会議肝細胞癌肝切除例における胆汁漏危険因子の検討ポスター発表
- 第２７回日本肝胆膵外科学会・学術集会, 2015年06月, 日本語, 国内会議肝切除後のドレーン留置は必要か？−術後胆汁漏リスク因子からの検討ーシンポジウム・ワークショップパネル（公募）
- 第２７回日本肝胆膵外科学会・学術集会, 2015年06月, 日本語, 国内会議肝門部胆管癌手術における術中超音波胆道造影法による胆管ドレナージ領域計測の有用性シンポジウム・ワークショップパネル（公募）
- 第33回日本肝移植研究会, 2015年05月, 日本語, 国内会議Piggyback法を用いた脳死肝移植術後outflow blockに対し下大静脈・肝静脈ステントを挿入した1例口頭発表（一般）
- 第115回日本外科学会定期学術集会, 2015年04月, 日本語, 国内会議臓器移植法改正後の急性肝不全に対する肝移植シンポジウム・ワークショップパネル（公募）
- 第115回日本外科学会定期学術集会, 2015年04月, 日本語, 国内会議独自の外科的先進技術を駆使した高度脈管侵襲陽性肝癌に対する治療戦略シンポジウム・ワークショップパネル（公募）
- 第31回近畿肝移植検討会プログラム, 2014年11月, 日本語, 国内会議移植後の管理に難渋したC型肝炎の1例口頭発表（一般）
- 第76回日本臨床外科学会総会, 2014年11月, 日本語, 国内会議ソラフェニブ著効により切除可能となった門脈腫瘍栓,下大静脈腫瘍栓,多発肺転移合併進行肝細胞癌の1例口頭発表（一般）
- 第76回日本臨床外科学会総会, 2014年11月, 日本語, 国内会議生体肝移植後胆管狭窄に対し,磁石圧迫吻合術にて狭窄部の開通を得た一例口頭発表（一般）
- 第76回日本臨床外科学会総会, 2014年11月, 日本語, 国内会議下大静脈損傷時の止血テクニックシンポジウム・ワークショップパネル（公募）
- The 1st International Congress of Living Donor Liver Transplantation Study Group(ILDLT), 2014年11月, 英語, 国際会議Low-dose antiviral treatment for hepatitis C virus following living donor liver transplantation without splenectomyポスター発表
- 第12回日本消化器外科学会大会(JDDW 2014), 2014年10月, 日本語, 国内会議肝移植後長期生着を目指してポスター発表
- 第69回日本消化器外科学会総会, 2014年07月, 日本語, 国内会議術前・術中肝生検を反映した新たな肝切除術式の立案シンポジウム・ワークショップパネル（公募）
- 第32回日本肝移植研究会, 2014年07月, 日本語, 国内会議生体肝移植後に直腸癌を発症し,術後肝転移と吻合部再発を併発した1例口頭発表（一般）
- 第36回日本癌局所療法研究会, 2014年06月, 日本語, 国内会議腸骨転移を伴う肝細胞癌に対し集学的治療で長期生存を得た一例口頭発表（一般）
- 第36回日本癌局所療法研究会, 2014年06月, 日本語, 国内会議粒子線治療後に再発した転移性肝癌の一切除例口頭発表（一般）
- 第50回日本肝癌研究会, 2014年06月, 日本語, 国内会議肝細胞癌切除後再発に対しsorafenibを含む集学的治療を行い長期生存を得た2例口頭発表（一般）
- 第50回日本肝癌研究会, 2014年06月, 日本語, 国内会議ラジオ波焼灼療法後再発肝癌に対する肝切除術口頭発表（一般）
- 第50回日本肝癌研究会, 2014年06月, 日本語, 国内会議肝細胞癌に対する肝切除における術前シミュレーションと術中ナビゲーション口頭発表（一般）
- 第50回日本肝癌研究会, 2014年06月, 日本語, 国内会議当科における混合型肝癌切除例の臨床病理学的検討シンポジウム・ワークショップパネル（公募）
- 第50回日本肝癌研究会, 2014年06月, 日本語, 国内会議Intermediate および Advanced Stage に対する外科切除を中心とする集学的治療シンポジウム・ワークショップパネル（公募）
- 第50回日本肝癌研究会, 2014年06月, 日本語, 国内会議独自の外科的先進技術を駆使した進行・大型肝癌に対する治療戦略シンポジウム・ワークショップパネル（公募）
- 第50回日本肝臓学会総会, 2014年05月, 日本語, 国内会議摘出肝線維化の術前評価方法口頭発表（一般）
- 第50回日本肝臓学会総会, 2014年05月, 日本語, 国内会議県内の肝疾患診療連携体制における当施設の役割シンポジウム・ワークショップパネル（公募）
- 第114回日本外科学会定期学術集会, 2014年04月, 日本語, 国内会議末期肝硬変患者における副腎機能評価の検討ポスター発表
- 第114回日本外科学会定期学術集会, 2014年04月, 日本語, 国内会議進行多発肝細胞癌に対する外科治療の役割ポスター発表
- 第114回日本外科学会定期学術集会, 2014年04月, 日本語, 国内会議新臨床研修制度導入後の外科医育成の取り組みポスター発表
- 11th World Congress of the International Hepato-Pancreato-Biliary Association(IHPBA), 2014年03月, 英語, 国際会議A novel algorithm for hepatectomy based on the fibrosis stageポスター発表
- 11th World Congress of the International Hepato-Pancreato-Biliary Association(IHPBA), 2014年03月, 英語, 国際会議Dual treatment; A novel strategy for highly-Advanced hepatocellular carcinomaポスター発表
- 第26回日本内視鏡外科学会総会, 2013年11月, 日本語, 国内会議当科における腹腔鏡下肝切除の工夫口頭発表（一般）
- 第75回日本臨床外科学会総会, 2013年11月, 日本語, 国内会議Denver型腹腔静脈シャント留置後に発症したDICに対し遺伝子組換え型トロンボモジュリンが著効した一例口頭発表（一般）
- 第75回日本臨床外科学会総会, 2013年11月, 日本語, 国内会議肝切除後に肝鎌状間膜内再発を来した肝細胞癌の一例口頭発表（一般）
- 第75回日本臨床外科学会総会, 2013年11月, 日本語, 国内会議進行肝細胞癌に対する術前化学療法としてのPIHP（経皮的肝灌流）の安全性と有用性の検討シンポジウム・ワークショップパネル（公募）
- 第75回日本臨床外科学会総会, 2013年11月, 日本語, 国内会議臓器移植法改正後の肝移植の現況シンポジウム・ワークショップパネル（公募）
- 第75回日本臨床外科学会総会, 2013年11月, 日本語, 国内会議当施設における外科医リクルート戦略口頭発表（一般）
- 第194回近畿外科学会, 2013年11月, 英語, 国内会議68Ga-DOTATOC-PETにて十二指腸原発巣を指摘し得た転移性肝神経内分泌腫瘍の一例口頭発表（一般）
- AASLD (THE LIVER MEETING2013), 2013年11月, 英語, 国際会議Usefulness of 99mTc-GSA scintigraphy on preoperative evaluation of liver function for hepatectomyポスター発表
- AASLD (THE LIVER MEETING2013), 2013年11月, 英語, 国際会議Assessment of ISGLS definition of posthepatectomy liver failure with hepatocellular carcinoma patientsポスター発表
- AASLD (THE LIVER MEETING2013), 2013年11月, 英語, 国際会議Graft type significantly associates with the incidence of posthepatectomy liver failure defined by ISGLS in living donors after hepatectomyポスター発表
- AASLD (THE LIVER MEETING2013), 2013年11月, 英語, 国際会議Dual treatment; a novel strategy for highly-advanced hepatocellular carcinomaポスター発表
- 第51回日本癌治療学会学術集会, 2013年10月, 日本語, 国内会議高濃度Cisplatinを用いた肝動注療法の実現に向けた動物モデルの構築と基礎検討ポスター発表
- 第55回日本消化器病学会大会(JDDW 2013), 2013年10月, 日本語, 国内会議臓器移植法改正後の劇症肝炎に対する肝移植ポスター発表
- 第11回日本消化器外科学会大会(JDDW 2013), 2013年10月, 日本語, 国内会議腹部固形癌に対する粒子線とスペーサー外科手術を用いた治療限界の克服ポスター発表
- 第11回日本消化器外科学会大会(JDDW 2013), 2013年10月, 日本語, 国内会議3㎝,3個以下の肝細胞癌に対する肝切除,生体肝移植の治療成績ポスター発表
- 第49回日本移植学会総会, 2013年09月, 日本語, 国内会議肝移植後長期合併症の管理口頭発表（一般）
- The 13th Congress of the Asian Society of Transplantation（CAST）, 2013年09月, 日本語, 国際会議Low-dose antiviral treatment for hepatitis C virus follwing living donor liver transplantation without splenectomy口頭発表（一般）
- 第68回日本消化器外科学会総会, 2013年07月, 日本語, 国内会議3㎝,3個以下の肝細胞癌に対する肝切除,生体肝移植の治療成績口頭発表（一般）
- 第68回日本消化器外科学会総会, 2013年07月, 日本語, 国内会議肝右葉切除の術前評価における99mTc-GSAシンチグラフィーの有用性シンポジウム・ワークショップパネル（公募）
- 第49回日本肝癌研究会, 2013年07月, 日本語, 国内会議非B非C肝細胞癌に対する外科切除症例の検討口頭発表（一般）
- 第49回日本肝癌研究会, 2013年07月, 日本語, 国内会議門脈腫瘍栓を伴う巨大肝癌に対する肝切除口頭発表（一般）
- 第49回日本肝癌研究会, 2013年07月, 日本語, 国内会議肝内胆管癌非治癒切除症例の検討シンポジウム・ワークショップパネル（指名）
- The 4th Asia-Pacific Primary Liver Cancer Expert Meeting(APPLE), 2013年07月, 英語, 国際会議The Utility of 99mTc-GSA Scintigraphy on Preoperative Evaluation of Liver Function for Major Hepatectomy.ポスター発表
- The 4th asia-Pacific Primary Liver Cancer Expert Meeting(APPLE), 2013年07月, 英語, 国際会議Treatment Strategy for Recurrent HCC.ポスター発表
- The 4th Asia-Pacific Primary Liver Cancer Expert Meeting(APPLE), 2013年07月, 英語, 国際会議Dual Treatment of Reductive Surgery and Sequential Parcutaneous Isolated Hepatic Perfusion for Multiple Bilobar Hepatocellular Carcinoma.ポスター発表
- 第31回日本肝移植研究会, 2013年07月, 日本語, 国内会議「生体肝移植ドナー手術におけるソナゾイドを用いた術中超音波下胆道造影法」口頭発表（一般）
- 第25回日本肝胆膵外科学会・学術集会, 2013年06月, 日本語, 国内会議肝細胞癌多発肺転移,リンパ節転移に対し集学的治療を行い,長期生存を得た1例口頭発表（一般）
- 第25回日本肝胆膵外科学会・学術集会, 2013年06月, 日本語, 国内会議高度脈管侵襲合併肝細胞癌に対する肝切除シンポジウム・ワークショップパネル（公募）
- 第25回日本肝胆膵外科学会・学術集会, 2013年06月, 日本語, 国内会議神戸大学における非B非C肝癌の外科的治療成績シンポジウム・ワークショップパネル（公募）
- 第25回日本肝胆膵外科学会・学術集会, 2013年06月, 日本語, 国内会議肝胆道外科領域における当科の術前シミュレーションの取り組みシンポジウム・ワークショップパネル（公募）
- 第25回日本肝胆膵外科学会・学術集会, 2013年06月, 日本語, 国内会議当科での肝癌に対する肝切除術の工夫シンポジウム・ワークショップパネル（公募）
- 第26回日本肝胆膵外科学会・学術集会, 2013年06月, 日本語, 国内会議肝切除における当科の術前シミュレーションの現状ポスター発表
- 第26回日本肝胆膵外科学会・学術集会, 2013年06月, 日本語, 国内会議肝内胆管癌切除例における切離断端陽性リスクの検討ポスター発表
- 第26回日本肝胆膵外科学会・学術集会, 2013年06月, 日本語, 国内会議vp1肝細胞癌の術後再発についての検討口頭発表（一般）
- 第26回日本肝胆膵外科学会・学術集会, 2013年06月, 日本語, 国内会議生体肝移植ドナー肝切除手術における術中超音波胆道造影法シンポジウム・ワークショップパネル（公募）
- 第26回日本肝胆膵外科学会・学術集会, 2013年06月, 日本語, 国内会議Vp4門脈腫瘍栓合併肝癌に対するBack Flow Thrombectomy法と経皮的肝灌流化学療法を用いた外科的治療戦略シンポジウム・ワークショップパネル（公募）
- 第35回日本癌局所療法研究会, 2013年05月, 日本語, 国内会議進行肝細胞癌に対する粒子線治療後にPIHPを施行した症例の検討シンポジウム・ワークショップパネル（公募）
- 第68回手術手技研究会, 2013年05月, 日本語, 国内会議神戸大学の再発肝癌に対する外科治療戦略：その適応と限界シンポジウム・ワークショップパネル（公募）
- 第113回日本外科学会定期学術集会, 2013年04月, 日本語, 国内会議肝移植医療のさらなる普及と脳死移植発展のために今必要とされることー市中病院および移植施設における移植外科医の役割ーポスター発表
- 第113回日本外科学会定期学術集会, 2013年04月, 日本語, 国内会議当科における成人生体肝移植後胆道合併症の現状ポスター発表
- 第113回日本外科学会定期学術集会, 2013年04月, 日本語, 国内会議80歳以上の高齢者における肝細胞癌切除例の検討ポスター発表
- 第113回日本外科学会定期学術集会, 2013年04月, 日本語, 国内会議肝細胞癌患者におけるPHLFの検討；新たな肝予備能評価方法の立案にむけてポスター発表
- 第113回日本外科学会定期学術集会, 2013年04月, 日本語, 国内会議高度門脈血栓合併症例に対する門脈再建術口頭発表（一般）
- 第113回日本外科学会定期学術集会, 2013年04月, 日本語, 国内会議肝胆道疾患におけるソナゾイドを用いた超音波下胆道造影による術中胆道ナビゲーションの有用性口頭発表（一般）
- 第113回日本外科学会定期学術集会, 2013年04月, 日本語, 国内会議外科的治療限界の克服：スペーサー手術と粒子線治療の融合口頭発表（一般）
- 第113回日本外科学会定期学術集会, 2013年04月, 日本語, 国内会議肝切除における肝静脈の重要性：ドナー手術の経験から口頭発表（一般）
- 2013 Gastrointestinal Cancers Symposium, 2013年01月, 英語, 国際会議Usefulness of FDG-PET in the evaluation of tumor response to proton bean therapy for locally advanced pancreatic ductal adenocarcinoma.ポスター発表
- 第25回日本内視鏡外科学会総会, 2012年12月, 日本語, 国内会議肝臓外科領域における当科の術前シミュレーション・術中ナビゲーションの取り組みシンポジウム・ワークショップパネル（公募）
- 第74回日本臨床外科学会総会, 2012年11月, 日本語, 国内会議ソナゾイドによる術中超音波胆道造影を用いた肝切除術口頭発表（一般）
- 第74回日本臨床外科学会総会, 2012年11月, 日本語, 国内会議Hanging maneuver を用いた巨大肝細胞癌に対する安全な肝右肝切除術口頭発表（一般）
- 第74回日本臨床外科学会総会, 2012年11月, 日本語, 国内会議門脈腫瘍栓(Vp4)合併肝細胞癌に対する肝切除の工夫と集学的治療としてのPIHPの有効性口頭発表（一般）
- 第6回肝臓内視鏡外科研究会, 2012年11月, 日本語, 国内会議当科における腹腔鏡下肝切除の導入と適応拡大口頭発表（一般）
- The 63rd Annual Meeting of the American Association for the Study of Liver Diseases（AASLD）, 2012年11月, 英語, 国際会議Fragility Index,a Novel Predictor to Assess Deterioration Speed of Renal Function after Living Donor Liver Transplantationポスター発表
- The 63rd Annual Meeting of the American Association for the Study of Liver Diseases（AASLD）, 2012年11月, 英語, 国際会議Long-Term Outcomes and Prognostic Factors with Reductive Hepatectomy and Sequential Percutaneous Isolated Hepatic Perfusion for Multiple Bilobar-Hepatocellular Carcinomaポスター発表
- The 9th Korea-Japan Transplantation Forum, 2012年10月, 英語, 国際会議Fragility Index, a Novel Predictor to Assess CKD after Living Donor Liver Transplantationポスター発表
- JDDW2012 第20回日本消化器関連学会週間（第10回日本消化器外科学会大会）, 2012年10月, 日本語, 国内会議高度脈管侵襲を伴う進行肝細胞癌に対する集学的治療ポスター発表
- 第48回日本移植学会総会, 2012年09月, 日本語, 国内会議門脈血栓症を合併した症例に対する門脈再建術の検討口頭発表（一般）
- 第48回日本肝癌研究会, 2012年07月, 日本語, 国内会議進行肝癌におけるGd-EOB-DTPA造影MRIの果たす役割口頭発表（一般）
- 第48回日本肝癌研究会, 2012年07月, 日本語, 国内会議腹腔鏡下ラジオ波焼灼術におけるNon Trocar Technique(NTT)の有用性口頭発表（一般）
- 第48回日本肝癌研究会, 2012年07月, 日本語, 国内会議完全鏡視下肝切除における新規デバイスの活用口頭発表（一般）
- 第48回日本肝癌研究会, 2012年07月, 日本語, 国内会議肝癌手術におけるソナゾイドを用いた術中胆道造影下超音波検査の有用性口頭発表（一般）
- 第48回日本肝癌研究会, 2012年07月, 日本語, 国内会議進行肝細胞癌に対する経皮的肝灌流(PIHP)の手技,プロトコールと治療成績口頭発表（一般）
- 第48回日本肝癌研究会, 2012年07月, 日本語, 国内会議門脈腫瘍栓合併進行肝癌に対する肝切除：Back Flow Perfusionによる腫瘍栓の摘出口頭発表（一般）
- 第67回日本消化器外科学会総会, 2012年07月, 日本語, 国内会議左葉を用いた成人生体肝移植における残肝還流障害を回避可能な術式選択シンポジウム・ワークショップパネル（公募）
- 第30回日本肝移植研究会, 2012年06月, 日本語, 国内会議「生体肝移植後長期腎機能障害を予測する新たな予後因子の立案」シンポジウム・ワークショップパネル（公募）
- 第34回日本癌局所療法研究会, 2012年06月, 日本語, 国内会議術前経皮的肝灌流と肝切除で完全奏功した両葉多発肝細胞癌の1例シンポジウム・ワークショップパネル（公募）
- 第34回日本癌局所療法研究会, 2012年06月, 日本語, 国内会議肝細胞癌での遠隔転移切除を含む集学的治療を行なった1例シンポジウム・ワークショップパネル（公募）
- 第48回日本肝臓学会総会, 2012年06月, 日本語, 国内会議神経内分泌腫瘍肝転移に対する肝切除の検討ポスター発表
- 第48回日本肝臓学会総会, 2012年06月, 日本語, 国内会議腹腔鏡下ラジオ波焼灼術におけるNon Trocar Techniqueの有用性ポスター発表
- 第48回日本肝臓学会総会, 2012年06月, 日本語, 国内会議進行肝細胞癌治療における経皮的肝灌流（PIHP)の位置付け〜さらなる成績の向上を目指して〜シンポジウム・ワークショップパネル（公募）
- 第48回日本肝臓学会総会, 2012年06月, 日本語, 国内会議C型肝炎肝硬変患者に対する移植後リバビリン・インターフェロン少量長期投与の有効性シンポジウム・ワークショップパネル（公募）
- 第24回日本肝胆膵外科学会・学術集会, 2012年05月, 日本語, 国内会議腹腔鏡下ラジオ波焼灼術におけるNon Trocar Techniqueの有用性口頭発表（一般）
- 第24回日本肝胆膵外科学会・学術集会, 2012年05月, 日本語, 国内会議Living Donor Liver Transplantation with Portal Vein Thrombus；Portal Vein Reconstruction Technique using Left Gastic Vein.口頭発表（一般）
- 第24回日本肝胆膵外科学会・学術集会, 2012年05月, 日本語, 国内会議肝細胞癌における術式選択；幕内基準を超えてシンポジウム・ワークショップパネル（公募）
- 第191回近畿外科学会, 2012年05月, 日本語, 国内会議肉腫成分を含む混合型肝癌の1例口頭発表（一般）
- 第66回手術手技研究会, 2012年05月, 日本語, 国内会議切除困難例に対する術前経皮的肝灌流化学療法と肝切除口頭発表（一般）
- 第112回日本外科学会定期学術集会, 2012年04月, 日本語, 国内会議生体肝移植後腎機能障害に対する予測式を用いた新たな治療戦略口頭発表（一般）
- 第112回日本外科学会定期学術集会, 2012年04月, 日本語, 国内会議高度進行肝癌に対する減量肝切除と PIHP による 2 段階治療の有効性と予後因子の解析シンポジウム・ワークショップパネル（公募）
- 5th International Forum of Liver Surgery, 2012年03月, 英語, 国内会議Feasibility to use a newly-developed Endoractor for laparoscopic hepatectomy.口頭発表（一般）
- 第14回関西肝癌局所療法研究会, 2012年03月, 日本語, 国内会議腹腔鏡下ラジオ派焼灼術におけるNon Trocar Technique(NTT法)の有用性口頭発表（一般）
- 第40回近畿肝臓外科研究会, 2012年02月, 日本語, 国内会議大血管侵襲を伴う肝細胞癌に対する肝切除口頭発表（一般）
- 第28回近畿肝移植検討会, 2011年12月, 日本語, 国内会議肝移植後C肝炎再発に対するリハビリン・インターフェロン少量投与の長期経過口頭発表（一般）
- 第73回日本臨床外科学会総会, 2011年11月, 日本語, 国内会議高度脈管浸潤を伴う進行肝癌に対する治療戦略シンポジウム・ワークショップパネル（公募）
- The 62st Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), 2011年11月, 英語, 国際会議Renal function deteriorates after living donor liver transplanation; how to predict chronic dysfunction?ポスター発表
- The 62st Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), 2011年11月, 英語, 国際会議Percutaneous isolated hepatic perfusion(PIHP)for advanced hepatocellular carcinoma:Two decades experience of Kobe programポスター発表
- JDDW 2011 第19回日本消化器関連学会週間（第9回消化器外科学会大会）, 2011年10月, 日本語, 国内会議神経内分泌腫瘍肝転移に対する肝切除の意義ポスター発表
- 第47回日本移植学会総会, 2011年10月, 日本語, 国内会議生体肝移植後長期の腎機能予測式口頭発表（一般）
- 12th Congress of the Asian Society of Transplantation (CAST 2011), 2011年09月, 英語, 国際会議A case report of severe PTLD after LDLT.ポスター発表
- 第65回手術手技研究会, 2011年09月, 日本語, 国内会議成人生体肝移植後のグラフト回転を考慮した新しい肝静脈再建法公開講演，セミナー，チュートリアル，講習，講義等
- International Liver Cancer Association Fifth Annual Conference （ILCA), 2011年09月, 英語, 国際会議Dual treatment; a novel strategy for highly-advanced hepatocellular carcinoma.ポスター発表
- International Liver Cancer Association Fifth Annual Conference （ILCA), 2011年09月, 英語, 国際会議Percutaneous isolated hepatic perfusion (PIHP) for advanced hepatocellular carcinoma: 20 years experience.ポスター発表
- 第47回日本肝癌研究会, 2011年07月, 日本語, 国内会議自然退縮を来した肝細胞癌の3切除例ポスター発表
- 第47回日本肝癌研究会, 2011年07月, 日本語, 国内会議外科切除成績からみた非Ｂ非Ｃ型肝癌の実態と特徴ポスター発表
- 第47回日本肝癌研究会, 2011年07月, 日本語, 国内会議当科における肝細胞癌切除後長期無再発症例の検討ポスター発表
- 第47回日本肝癌研究会, 2011年07月, 日本語, 国内会議当施設における肝切除の適応および限界～腹腔鏡下から腫瘍栓摘出まで～口頭発表（一般）
- 第29回日本肝移植研究会, 2011年07月, 日本語, 国内会議「生体肝移植後腎機能障害に対する新たな治療戦略」口頭発表（一般）
- 第66回日本消化器外科学会総会, 2011年07月, 日本語, 国内会議陽子線治療にてVp4門脈腫瘍栓を制御後,経皮的肝灌流化学療法（PIHP）を施行した1例口頭発表（一般）
- The 2nd Asia-Pacific Primary Liver Cancer Expert Meeting 2011 (APPLE), 2011年07月, 英語, 国際会議Significant role of Reductive Surgery for patients with Huge Hepatocellular Carcinomaポスター発表
- The 2nd Asia-Pacific Primary Liver Cancer Expert Meeting 2011 (APPLE), 2011年07月, 英語, 国際会議Feasibility to use a newly-developed Endoractor for laparoscopic hepatectomyポスター発表
- 第33回日本癌局所療法研究会, 2011年06月, 日本語, 国内会議肺癌肝転移の診断でRFAを施行するも再発した肝内胆管癌の1切除例シンポジウム・ワークショップパネル（公募）
- 第33回日本癌局所療法研究会, 2011年06月, 日本語, 国内会議肝切除,粒子線治療併用にて治療効果を認めた両葉多発肝癌の1例シンポジウム・ワークショップパネル（公募）
- 第23回日本肝胆膵外科学会・学術集会, 2011年06月, 日本語, 国内会議陽子線治療にてVp4門脈腫瘍栓を制御後,経皮的肝灌流化学療法（PIHP）を施行した1例ポスター発表
- 第39回近畿肝臓外科研究会, 2011年02月, 日本語, 国内会議「多発転移性肝癌に対する外科治療の意義」口頭発表（一般）
- 第72回日本臨床外科学会総会, 2010年11月, 日本語, 国内会議自然退縮を来した肝細胞癌の3例口頭発表（一般）
- 第69回日本臨床外科学会総会, 2007年11月, 日本語, 国内会議巨大な肝動脈瘤を随伴したFNHの一例ポスター発表
- 第87回日本消化器病学会近畿支部例会, 2007年09月, 日本語, 国内会議肺炎・胸膜炎を契機に発見された食道アカラシアの1例口頭発表（一般）