研究活動情報

• 2024年04月 公益社団法人日本化学会, 第 104 春季年会(2024) 「学生講演賞」, カルバゾマイシンＡ–Ｄのグラムスケール合成

  馮 宇軒

• Highly Efficient and Stable Ni–W Nanoalloy Catalyst for Selective Hydrogenation of Nitriles to Secondary Amines

  Taiki Kawakami, Yuxuan Feng, Kentaro Okano, Sho Yamaguchi

  American Chemical Society (ACS), 2026年07月, ACS Catalysis

  [査読有り]

  研究論文（学術雑誌）


• Regioselective Deprotonative Metalation of Heteroarenes with a Combination of Lithium Amide and Zinc Chloride Diamine Complex

  Yuxuan Feng, Atsunori Mori, Kentaro Okano

  American Chemical Society (ACS), 2025年08月, The Journal of Organic Chemistry, 90(33) (33), 12007 - 12016

  [査読有り]

  研究論文（学術雑誌）


• Gram-Scale Total Synthesis of Carbazomycins A–D through Late-Stage Regioselective Demethylation of Aryl Methyl Ethers

  Yuxuan Feng, Atsunori Mori, Kentaro Okano

  American Chemical Society (ACS), 2024年09月, The Journal of Organic Chemistry, 89(18) (18), 13472 - 13484

  [査読有り]

  研究論文（学術雑誌）


• Total Synthesis of Carbazomycins E and F

  Yunosuke Shima, Yuxuan Feng, Atsunori Mori, Kentaro Okano

  2024年05月, The Journal of Organic Chemistry, 89(11) (11), 8185 - 8191, 英語

  [査読有り]

  研究論文（学術雑誌）


• Deprotonative Generation and Trapping of Haloaryllithium in a Batch Reactor

  Yuxuan Feng, Taro Yukioka, Mei Matsuyama, Atsunori Mori, Kentaro Okano

  American Chemical Society (ACS), 2023年04月, Organic Letters, 25(17) (17), 3013 - 3017

  [査読有り]

  研究論文（学術雑誌）


• “Snapshot” Trapping of Multiple Transient Azolyllithiums in Batch

  Kengo Inoue, Yuxuan Feng, Atsunori Mori, Kentaro Okano

  Abstract Recent developments in flow microreactor technology have allowed the use of transient organolithium compounds that cannot be realized in a batch reactor. However, trapping the transient aryllithiums in a “halogen dance” is still challenging. Herein is reported the trapping of such short‐lived azolyllithiums in a batch reactor by developing a finely tuned in situ zincation using zinc halide diamine complexes. The reaction rate is controlled by the appropriate choice of diamine ligand. The reaction is operationally simple and can be performed at 0 °C with high reproducibility on a multigram scale. This method was applicable to a wide range of brominated azoles allowing deprotonative functionalization, which was used for the concise divergent syntheses of both constitutional isomers of biologically active azoles.

  Wiley, 2021年05月, Chemistry – A European Journal, 27(40) (40), 10267 - 10273

  [査読有り]

  研究論文（学術雑誌）