Research activity information

• Cross-sectional Associations of Serum Sodium, Potassium, and Chloride with Cognition in Patients on Hemodialysis: The Osaka Dialysis Complication Study (ODCS).

  Tetsuo Shoji, Shinya Nakatani, Katsuhito Mori, Daijiro Kabata, Hisako Fujii, Rino Nakaya, Hideki Uedono, Yuki Nagata, Yasuo Imanishi, Tomoaki Morioka, Masanori Emoto

  RATIONALE & OBJECTIVES: Cognitive function is impaired in patients with chronic kidney disease, particularly in those undergoing hemodialysis, although the precise mechanisms are not well understood. This cross-sectional study examined the possible relationship between serum electrolyte levels and cognitive function in patients receiving maintenance hemodialysis. STUDY DESIGN: Cross-sectional study. SETTINGS & PARTICIPANTS: Eligible patients were selected from the participants of the Osaka Dialysis Complication Study, a multicenter study conducted in Japan. EXPOSURES: Serum sodium, potassium, and chloride levels. OUTCOMES: Cognitive function assessed by the Modified Mini-Mental State examination (3MS) which was mathematically transformed to 3MS' to follow a normal distribution. ANALYTICAL APPROACH: Multivariable-adjusted linear regression analysis. RESULTS: For this study, 1,207 patients were selected. Their median age, 3MS score, serum sodium, potassium, and chloride concentrations were 67 (IQR, 60-74) years, 91 (IQR, 82-97) points, 139 (IQR, 137-141) mEq/L, 4.7 (IQR, 4.2-5.2) mEq/L, and 102 (IQR, 99-105) mEq/L, respectively. After adjustment, sodium (P = 0.23) or potassium (P = 0.38) were not associated with the 3MS score, whereas serum chloride was positively associated with the 3MS score (3MS', regression coefficient 0.100 [0.062, 0.138] per 1 IQR (6 mEq/L), P < 0.001) independently of potential confounders. The positive association between serum chloride and cognition was consistent in subgroup analysis. The difference in the 3MS score by 1 IQR of chloride was comparable to that of the difference by 7 years of age. LIMITATIONS: Causality cannot be determined because of the cross-sectional design. CONCLUSIONS: This study revealed that serum chloride level was a novel factor independently associated with cognitive performance in patients on maintenance hemodialysis, suggesting an unrecognized role of chloride in cognition.

  Jun. 2026, Kidney medicine, 8(6) (6), 101369 - 101369, English, International magazine

  [Refereed]

  Scientific journal


• Double/debiased machine learning for causal inference on survival function: an application to the role of e-learning programme on unemployment duration

  Daijiro Kabata, Mototsugu Shintani

  Lead, May 2026, APPLIED ECONOMICS LETTERS, English

  [Refereed]

  Scientific journal


• Age-Dependent Variation in Blood Biopterin Peaks Following Oral Tetrahydrobiopterin Administration in Phenylketonuria.

  Kana Kitayama, Tomoko Sakaguchi, Noriko Nakano, Daijiro Kabata, Haruo Shintaku, Takashi Hamazaki

  The correct diagnosis of tetrahydrobiopterin (BH4, sapropterin dihydrochloride)-responsive phenylketonuria (PKU) and treatment with BH4 are important for prognosis and quality of life. We examined whether age affects biopterin bioavailability following oral BH4 administration in PKU and whether this influences BH4 responsiveness. A retrospective analysis was conducted in 255 Japanese PKU patients who underwent a 24-h BH4 loading test (mostly ≤ 2 months old) and/or a 1-week test (all ≥ 5 months) between 2008 and 2023. Correlations were evaluated among age, peak blood biopterin, and the phenylalanine (Phe) reduction rate. In the 24-h test, analyses of day-of-age versus peak biopterin after oral BH4 showed that peak levels were highest during the early neonatal period and declined significantly with age (p = 0.008). In the 1-week test, peak levels increased during school age through adolescence (6-19 years) (p = 0.001), with no material age trend in adults (≥ 20 years). In the 24-h test, peak biopterin correlated positively with the Phe reduction rate (p = 0.029), and baseline Phe correlated negatively with peak biopterin (p = 0.001). These findings indicate that BH4 loading tests performed in infants and preschool-aged children (1 month-5 years)-in whom biopterin peaks tend to be low-or in patients with high baseline Phe levels may yield suppressed biopterin peaks and false-negative results. Reassessment of BH4 responsiveness and age-appropriate dose adjustment should be considered when necessary.

  Feb. 2026, Journal of inherited metabolic disease, 49(2) (2), e70154, English, International magazine

  [Refereed]

  Scientific journal


• Antenatal Magnesium Sulfate for Tocolysis and Early Enteral Feeding in Preterm Infants: A Retrospective Cohort Study.

  Takashi Okuno, Daijiro Kabata, Tatsuto Shimizu, Aiko Igarashi, Yusei Ohshima, Katsutsugu Umeda

  BACKGROUND: Antenatal administration of magnesium sulfate (MgSO4) is employed for fetal neuroprotection, and its extended use for tocolysis remains prevalent in certain regions. The impact of MgSO4 on neonatal gastrointestinal function is contentious, with evidence indicating variability across subpopulations. METHODS: A single-center retrospective cohort study examined preterm infants with a birth weight below 1500 g, admitted to the neonatal intensive care unit at the University of Fukui Hospital, Japan, between April 2015 and October 2023. Among 141 eligible infants, 83 received antenatal MgSO4 within 1 month before delivery, while 58 did not. Exposure was defined as duration, cumulative dose, and neonatal serum magnesium concentration. The primary outcome was time to achieve full enteral feeding (100 mL/kg/day). Associations were estimated using Cox proportional hazards models with inverse probability weighting to evaluate the effects of gestational and maternal age. RESULTS: Antenatal MgSO4 exposure was not significantly associated with time to full enteral feeding (HR, 0.80; 95% CI, 0.59-1.10). Multivariable weighted models suggested heterogeneity of association across gestational and maternal age strata (P for interaction < 0.001). HRs increased with gestational age in each maternal age stratum, suggesting antenatal MgSO4 exposure was more associated with delayed full enteral feeding at earlier gestational ages, especially among older mothers. CONCLUSIONS: Antenatal MgSO4 exposure was not significantly associated with delayed enteral feeding, and gestational and maternal ages may explain the conflicting results. These findings suggest that the association between antenatal MgSO4 and enteral feeding progression varies according to gestational maturity and maternal characteristics.

  2026, Pediatrics international : official journal of the Japan Pediatric Society, 68(1) (1), e70446, English, International magazine

  [Refereed]

  Scientific journal


• Different associations of stay-at-home exposure with changes in body mass index and Cardiometabolic factors depending on occupational physical activity: a longitudinal quasi-experimental design.

  Daijiro Kabata, Noriaki Kakiuchi, Takashi Marui, Naoko Ikeda, Mutsuko Kawai, Aki Kaimori, Noriko Saeki, Katsufumi Kajimoto, Riho Tanaka, Ayumi Zeniya, Fumi Yamanouchi, Saori Matsumiya, Yukihiro Koretsune

  OBJECTIVES: To quantify the short-term impact of an unexpected stay-at-home exposure caused by the shipment suspension on body mass index (BMI) and cardiometabolic markers among employees with different levels of occupational physical activity. METHODS: Health-check records from 8307 workers at a large Japanese automobile manufacturer were linked to company attendance data covering the shipment suspension (January-April 2024). An interrupted time-series assessed BMI trajectories before, during and after the halt. Among 614 employees who underwent an additional examination in April 2024, mixed-effects models related the duration of stay-at-home to changes in BMI and blood pressure within low-, medium- and high-intensity job categories. RESULTS: Compared with pre-halt trends, medium-intensity and high-intensity workers showed significant level rises (0.96 kg/m2; 95% CI 0.56-1.36 and 0.64 kg/m2; 95% CI 0.24-1.04, respectively) at the onset of the suspension.. Mixed-effects analyses showed a positive dose-response between the duration of stay-at-home and BMI gain in high-intensity jobs (0.47 kg/m2 per 20% absent days; 95% CI 0.37-0.58. Per 20% of scheduled workdays absent, systolic blood pressure was higher in the medium- and high-intensity groups. No significant effects were observed among sedentary workers. CONCLUSIONS: Employees whose daily energy expenditure relies on job-related physical activity are especially susceptible to weight gain and blood-pressure elevations during forced work interruptions. Business continuity plans should embed tailored countermeasures-such as structured exercise programs and phased returns to on-site duties-to safeguard metabolic health during future operational disruptions.

  Nov. 2025, Journal of occupational health, English, International magazine

  [Refereed]

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Quantifying uncertainty of individualized treatment effects in right-censored survival data: A comparison of Bayesian additive regression trees and causal survival forest

  Daijiro Kabata, Nicholas C. Henderson, Ravi Varadhan

  Lead, Nov. 2025, Health Searvices Outcome Research Methodology, in Press

  [Refereed]


• Distribution of blood pressure and its positive association with body mass index standard deviation score in pediatric patients with X-linked hypophosphatemia: a sub-group analysis from the SUNFLOWER observational study.

  Kaori Fujiwara, Daijiro Kabata, Ryota Kawai, Hee Gyung Kang, Noriyuki Namba, Nobuaki Ito, Ayumi Shintani, Seiji Fukumoto, Keiichi Ozono, Toshimi Michigami

  Few studies have investigated the distribution of blood pressure (BP) and associated factors in pediatric patients with X-linked hypophosphatemic rickets (XLH). We analyzed snapshot baseline data from the SUNFLOWER study, a longitudinal observational cohort study of patients with XLH in Japan and South Korea (NCT03745521/UMIN000031605). We used data from pediatric participants aged 5-17 years who were 120-189.9 cm (males) and 120-179.9 cm (females) in height and had a history of conventional treatment. Systolic and diastolic BP (SBP and DBP, respectively) were categorized into percentile ranks based on age, sex, and height. Ordinal logistic regression analyses were performed to investigate the association between BP and exposure factors, including estimated glomerular filtration rate, serum intact parathyroid hormone levels, serum intact fibroblast growth factor 23 levels, urinary calcium/creatinine ratio, and body mass index standard deviation score (BMI-SDS). Forty-five participants were eligible for the subgroup analysis. Of these, 44 were evaluated after one patient with missing BP data was excluded. After height adjustment, three patients (6.8%) were at or above the 95th percentile for SBP, and five (11.4%) were at or above the 95th percentile for DBP. Regarding age adjustment, one patient (2.3%) was at or above the 95th percentile for SBP and three (6.8%) were at or above the 95th percentile for DBP. In the association analysis, age- and height-adjusted BP was positively correlated with BMI-SDS. These results suggest that some pediatric patients with XLH exhibit high BP and that a high BMI-SDS may be a risk factor.

  Oct. 2025, Endocrine journal, English, Domestic magazine

  [Refereed]

  Scientific journal


• Correction: Estimated T50 calciprotein crystallization test in patients undergoing hemodialysis: Osaka Dialysis Complication Study (ODCS).

  Tetsuo Shoji, Daijiro Kabata, Yu Nagakura, Shinya Nakatani, Hideki Uedono, Yuki Nagata, Hisako Fujii, Katsuhito Mori, Yasuo Imanishi, Tomoaki Morioka, Masanori Emoto

  Sep. 2025, Clinical and experimental nephrology, English, Domestic magazine

  [Refereed]


• Impact of Metabolic Syndrome on Renal and Cardiovascular Outcomes in Renal Transplant Recipients: A Single-Center Study in Japan

  Toshihide Naganuma, Tomoaki Iwai, Daijiro Kabata, Yuichi Machida, Yoshiaki Takemoto, Junji Uchida

  Jul. 2025, Journal of Clinical Medicine, 14(15) (15), 5303 - 5303, English, International magazine

  [Refereed]

  Scientific journal


• Estimated T50 calciprotein crystallization test in patients undergoing hemodialysis: Osaka Dialysis Complication Study (ODCS).

  Tetsuo Shoji, Daijiro Kabata, Yu Nagakura, Shinya Nakatani, Hideki Uedono, Yuki Nagata, Hisako Fujii, Katsuhito Mori, Yasuo Imanishi, Tomoaki Morioka, Masanori Emoto

  Jul. 2025, Clinical and experimental nephrology, English, Domestic magazine

  [Refereed]

  Scientific journal


• A new acute pain service fee addition in Japan: a nationwide study based on a reimbursement claims database.

  Yuta Nonomiya, Hiroshi Morimatsu, Kaori Kuriu, Daijiro Kabata, Ayumi Shintani

  Jun. 2025, Journal of anesthesia, 39(5) (5), 719 - 730, English, Domestic magazine

  [Refereed]

  Scientific journal


• Caloric Intake at Lunch Does Not Mediate the Impact of Eating Rate on Weight Gain Among Healthy Adults: Longitudinal Cohort Study.

  Daijiro Kabata, Saori Matsumiya, Fumi Yamanouchi, Noriko Saeki, Katsufumi Kajimoto, Aki Kaimori, Riho Tanaka, Ayumi Zeniya, Yukihiro Koretsune

  Apr. 2025, American journal of health promotion : AJHP, 39(7) (7), 8901171251335778 - 8901171251335778, English, International magazine

  [Refereed]

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• A systematic review and meta-analysis of diagnostic performance comparison between generative AI and physicians

  Hirotaka Takita, Daijiro Kabata, Shannon L. Walston, Hiroyuki Tatekawa, Kenichi Saito, Yasushi Tsujimoto, Yukio Miki, Daiju Ueda

  Mar. 2025, npj Digital Medicine, 8(1) (1), 175 - 175, English, International magazine

  [Refereed]

  Scientific journal


• Clinical predictors of extubation failure in postoperative critically ill patients: a post-hoc analysis of a multicenter prospective observational study.

  Jun Hattori, Aiko Tanaka, Junko Kosaka, Osamu Hirao, Nana Furushima, Yuichi Maki, Daijiro Kabata, Akinori Uchiyama, Moritoki Egi, Hiroshi Morimatsu, Satoshi Mizobuchi, Yoshifumi Kotake, Ayumi Shintani, Yukiko Koyama, Takeshi Yoshida, Yuji Fujino

  Mar. 2025, BMC anesthesiology, 25(1) (1), 127 - 127, English, International magazine

  [Refereed]

  Scientific journal


• Prevalence of Comorbid Hyperparathyroidism and Its Association with Renal Dysfunction in Asian Patients with X-Linked Hypophosphatemic Rickets/Osteomalacia.

  Nobuaki Ito, Hee Gyung Kang, Toshimi Michigami, Noriyuki Namba, Takuo Kubota, Ayumi Shintani, Ryota Kawai, Daijiro Kabata, Haruka Ishii, Yayoi Nishida, Seiji Fukumoto, Keiichi Ozono

  Mar. 2025, Calcified tissue international, 116(1) (1), 50 - 50, English, International magazine

  [Refereed]

  Scientific journal


• Efficacy of 1 L polyethylene glycol plus ascorbic acid with linaclotide versus senna for bowel preparation: A multicenter, endoscopist-blinded, randomized controlled trial (Apple trial).

  Natsumi Maeda, Akira Higashimori, Daijiro Kabata, Ikki Yamamoto, Tsuyoshi Yanagida, Daiyu Kin, Yuji Matsumoto, Rieko Nakata, Atsushi Hashimoto, Akinari Sawada, Hirotsugu Maruyama, Junichi Okamoto, Takayuki Katsuno, Yuji Nadatani, Masaki Ominami, Shusei Fukunaga, Kenichi Morimoto, Shuhei Hosomi, Fumio Tanaka, Masami Nakatani, Koichi Taira, Eiji Sasaki, Takashi Fukuda, Keiko Ota, Hisako Yoshida, Toshio Watanabe, Yasuhiro Fujiwara

  OBJECTIVES: No bowel preparation for colonoscopy achieves optimal efficacy and tolerability. Combining polyethylene glycol plus ascorbic acid (PEG-Asc) with adjuvants has been explored to enhance cleansing efficacy and reduce the required volume. This study aimed to evaluate whether adding 0.5 mg linaclotide to 1-L PEG-Asc (1 L-PEG/AL) improves superior cleansing compared to adding 24 mg senna (1 L-PEG/AS), which we previously reported to be non-inferior to the standard regimen of 2 L PEG-Asc. METHODS: A multicenter, endoscopist-blinded, randomized controlled trial was conducted at five centers in Japan with outpatients scheduled for colonoscopy. The primary outcome was adequate bowel preparation (BP), evaluated using the Boston Bowel Preparation Scale. Analyses were stratified based on low- and high-risk groups for inadequate BP. RESULTS: Between April 2022 and April 2023, 1,464 patients were randomized to the 1L-PEG/AL (n=733) or 1L-PEG/AS (n=731). The 1L-PEG/AL demonstrated higher adequate BP rates (92% vs. 86%, P=0.001) compared to 1L-PEG/AS. Both groups experienced similar adverse events and expressed high willingness for repeat BP (83% vs. 81%, P=0.49). In high-risk patients (n=892), 1L-PEG/AL had significantly higher adequate BP rates (94% vs. 86%, P<0.001), whereas rates were comparably high in low-risk patients (n=539) (94% vs. 94%, P=0.66). CONCLUSIONS: The linaclotide regimen was superior to the senna regimen in terms of BP efficacy without reducing tolerability. It can be a promising new option for BP, especially in patients at a high-risk of inadequate BP.

  Feb. 2025, The American journal of gastroenterology, English, International magazine

  [Refereed]

  Scientific journal


• The Surprise Question in Hemodialysis, Frailty, Nutrition, Patient-reported Quality of Life, and All-Cause Mortality: The Osaka Dialysis Complication Study (ODCS).

  Tetsuo Shoji, Daijiro Kabata, Seiichi Kimura, Yuki Nagata, Katsuhito Mori, Shinya Nakatani, Hisako Fujii, Tomoaki Morioka, Masanori Emoto

  Dec. 2024, Kidney medicine, 6(12) (12), 100914 - 100914, English, International magazine

  [Refereed]

  Scientific journal


• Associations of Cognitive Function with Serum Magnesium and Phosphate in Hemodialysis Patients: A Cross-Sectional Analysis of the Osaka Dialysis Complication Study (ODCS).

  Tetsuo Shoji, Katsuhito Mori, Yu Nagakura, Daijiro Kabata, Kaori Kuriu, Shinya Nakatani, Hideki Uedono, Yuki Nagata, Hisako Fujii, Yasuo Imanishi, Tomoaki Morioka, Masanori Emoto

  Nov. 2024, Nutrients, 16(21) (21), English, International magazine

  [Refereed]

  Scientific journal


• Impact of X-linked hypophosphatemic rickets/osteomalacia on health and quality of life: baseline data from the SUNFLOWER longitudinal, observational cohort study.

  Noriyuki Namba, Nobuaki Ito, Toshimi Michigami, Hee Gyung Kang, Takuo Kubota, Osamu Miyazaki, Ayumi Shintani, Daijiro Kabata, Yayoi Nishida, Seiji Fukumoto, Keiichi Ozono

  Nov. 2024, JBMR plus, 8(11) (11), ziae118, English, International magazine

  [Refereed]

  Scientific journal


• Prognostic score-based model averaging approach for propensity score estimation

  Daijiro Kabata, Elizabeth A. Stuart, Ayumi Shintani

  Oct. 2024, BMC Medical Research Methodology, 24(1) (1), 228 - 228, English, International magazine

  [Refereed]

  Scientific journal

  Link to Kobe Univ. Repository (Kernel)


• Comment on: Deleterious effects of a combination therapy using fluoroquinolones and tetracyclines for the treatment of Japanese spotted fever: a retrospective cohort study based on a Japanese hospital database.

  Kazuhiro Itoh, Hiroshi Tsutani, Daijiro Kabata, Shigetoshi Sakabe, Yasuhiko Mitsuke, Hiromichi Iwasaki

  Oct. 2024, The Journal of antimicrobial chemotherapy, 79(11) (11), 3049 - 3050, English, International magazine

  [Refereed]


• Burosumab treatment of X-linked hypophosphatemia patients: interim analysis of the SUNFLOWER longitudinal, observational cohort study.

  Toshimi Michigami, Hee Gyung Kang, Noriyuki Namba, Nobuaki Ito, Takuo Kubota, Ayumi Shintani, Daijiro Kabata, Masanori Kanematsu, Yayoi Nishida, Seiji Fukumoto, Keiichi Ozono

  Aug. 2024, JBMR plus, 8(8) (8), ziae079, English, International magazine

  [Refereed]

  Scientific journal


• In reply to the Letter to Editor regarding "Evaluation of tetracycline and fluoroquinolone therapy against Japanese spotted fever: Analysis based on individual data from case reports and case series".

  Kazuhiro Itoh, Daijiro Kabata, Hiroko Shigemi, Tomoya Hirota, Ippei Sakamaki, Hiroshi Tsutani, Yasuhiko Mitsuke, Hiromichi Iwasaki

  Jun. 2024, International journal of antimicrobial agents, 64(2) (2), 107246 - 107246, English, International magazine

  [Refereed]


• Association between skin suture devices and incidence of incisional surgical site infection after gastrointestinal surgery: A systematic review and network meta-analysis.

  Keita Kouzu, Daijiro Kabata, Hiroji Shinkawa, Seiichi Shinji, Tomohiro Ishinuki, Koji Tamura, Motoi Uchino, Hiroki Ohge, Junzo Shimizu, Seiji Haji, Yasuhiko Mohri, Chizuru Yamashita, Yuichi Kitagawa, Katsunori Suzuki, Motomu Kobayashi, Masahiro Kobayashi, Yuki Hanai, Hiroshi Nobuhara, Hiroki Imaoka, Masahiro Yoshida, Toru Mizuguchi, Toshihiko Mayumi, Yuko Kitagawa

  AIM: We aimed to compare which suture devices could reduce the incidence of incisional surgical site infections (SSIs) after gastrointestinal surgery using a systematic review and network meta-analysis. METHODS: The CENTRAL, PubMed, and ICHUSHI-Web databases were searched from January 1st, 2000, to December 31st, 2022, for randomised clinical trials (RCTs) comparing the incidence of incisional SSI after gastrointestinal surgery among patients treated with different surgical suture devices, including non-absorbable sutures, absorbable sutures, skin staplers, and tissue adhesives (last searched in August 23th 2023). The risk of bias was assessed using the criteria of the Cochrane Handbook for Systematic Reviews of Interventions. To estimate the pooled odds ratios (ORs) for each comparison, we employed a fixed-effect inverse-variance model based on the Mantel-Haenszel approach. This study was registered in PROSPERO and supported in part by the Japan Surgical Infection Society. RESULTS: A total of 18 RCTs with 5,496 patients were included in this study. The overall SSIs in absorbable sutures were significantly lower than the ones in skin staplers (OR: 0.77; 95% confidence intervals (CI): 0.63-0.95) and non-absorbable sutures (OR: 0.62; 95% CI: 0.39-0.99). On the other hand, SSIs in absorbable sutures were not statistically different from the SSIs in tissue adhesive. The highest P-score was 0.91 for absorbable sutures. A funnel plot for estimating the heterogeneity of the studies revealed that a publication bias would be minimal (Egger test, P = 0.271). CONCLUSION: This study showed that absorbable sutures reduced incisional SSIs in gastrointestinal surgical operations compared to any other suture devices.

  Jun. 2024, The Journal of hospital infection, English, International magazine

  [Refereed]

  Scientific journal


• Health guidance intervention mitigates the escalation of predicted comprehensive cardiovascular disease risk: Interrupted time series design.

  Daijiro Kabata, Noriko Saeki, Katsufumi Kajimoto, Riho Tanaka, Noriaki Kakiuchi, Ayumi Shintani, Yukihiro Koretsune

  Apr. 2024, Preventive medicine, 183, 107972 - 107972, English, International magazine

  [Refereed]

  Scientific journal


• Amino acids to prevent cardiac surgery-associated acute kidney injury: a randomized controlled trial.

  Masahiro Kazawa, Daijiro Kabata, Hisako Yoshida, Kimito Minami, Takuma Maeda, Kenji Yoshitani, Hitoshi Matsuda, Ayumi Shintani

  Mar. 2024, JA clinical reports, 10(1) (1), 19 - 19, English, International magazine

  [Refereed]

  Scientific journal


• Japanese study of the effects of AMG (α1-microglobulin) reduction rates on survival (JAMREDS): protocol of a multicenter prospective observational cohort study.

  Toshihide Naganuma, Yoshiaki Takemoto, Naohiro Kamada, Daijiro Kabata, Ayumi Shintani, Keiko Ota, Jun Minakuchi, Ken Tsuchiya, Hideki Kawanishi

  Feb. 2024, Blood purification, 53(6) (6), 527 - 532, English, International magazine

  [Refereed]

  Scientific journal


• Changes in FeNO, d-ROMs, and BH4 by Intravenous L-Arginine in Children and Its Putative Role in Asthma Treatment.

  Naho Yamamoto, Saki Kasuga, Daijiro Kabata, Myu Ono, Sakura Ando, Taisuke Hashimoto, Shiori Fujikawa, Hiroko Fujitani, Ayumi Shintani, Takashi Hamazaki

  2024, Journal of asthma and allergy, 17, 251 - 259, English, International magazine

  [Refereed]

  Scientific journal


• Laparoscopic and open minor liver resection for hepatocellular carcinoma with clinically significant portal hypertension: a multicenter study using inverse probability weighting approach.

  Hiroji Shinkawa, Masaki Kaibori, Daijiro Kabata, Takuya Nakai, Masaki Ueno, Daisuke Hokuto, Hisashi Ikoma, Hiroya Iida, Koji Komeda, Shogo Tanaka, Hisashi Kosaka, Chihoko Nobori, Shinya Hayami, Satoshi Yasuda, Ryo Morimura, Haruki Mori, Shuji Kagota, Shoji Kubo, Takeaki Ishizawa

  Dec. 2023, Surgical endoscopy, 38(2) (2), 757 - 768, English, International magazine

  [Refereed]

  Scientific journal


• Relationship between Full-Thickness Macular Hole Onset and Posterior Vitreous Detachment: A Temporal Onset Theory.

  Hirokazu Sakaguchi, Daijiro Kabata, Susumu Sakimoto, Akihiko Shiraki, Hisataka Fujimoto, Yoko Fukushima, Chikako Hara, Kentaro Nishida, Ayumi Shintani, Kohji Nishida

  Dec. 2023, Ophthalmology science, 3(4) (4), 100339 - 100339, English, International magazine

  [Refereed]

  Scientific journal


• On propensity score misspecification in double/debiased machine learning for causal inference: ensemble and stratified approaches

  Daijiro Kabata, Mototsugu Shintani

  Nov. 2023, Communications in Statistics - Simulation and Computation, 1 - 11, English

  [Refereed]

  Scientific journal


• Matching on propensity and prognostic scores can lead to different estimates of heterogeneous treatment effects: a case study and simulation

  Daijiro Kabata, Yasufumi Gon, Ayumi Shintani

  Sep. 2023, Health Services and Outcomes Research Methodology, 24(2) (2), 227 - 238, English

  [Refereed]

  Scientific journal


• Evaluation of tetracycline and fluoroquinolone therapy against Japanese spotted fever: Analysis based on individual data from case reports and case series.

  Kazuhiro Itoh, Daijiro Kabata, Hiroko Shigemi, Tomoya Hirota, Ippei Sakamaki, Hiroshi Tsutani, Yasuhiko Mitsuke, Hiromichi Iwasaki

  Aug. 2023, International journal of antimicrobial agents, 62(2) (2), 106895 - 106895, English, International magazine

  [Refereed]

  Scientific journal


• Clinical features and risk factors for interstitial lung disease spreading in low-dose irradiated areas after definitive radiotherapy with or without durvalumab consolidation therapy for patients with non-small cell lung cancer

  Mai Sakagami, Haruo Inokuchi, Nobutaka Mukumoto, Hiroshige Itoyama, Nobunari Hamaura, Mutsumi Yamagishi, Naoki Mukumoto, Shogo Matsuda, Daijiro Kabata, Keiko Shibuya

  May 2023, RADIATION ONCOLOGY, 18(1) (1), 87 - 87, English, International magazine

  [Refereed]

  Scientific journal


• Association of Serum Levels of Cholesterol Absorption and Synthesis Markers with the Presence of Cardiovascular Disease: The CACHE Study CVD Analysis.

  Shunsuke Katsuki, Tetsuya Matoba, Yusuke Akiyama, Hiroshi Yoshida, Kazuhiko Kotani, Hisako Fujii, Mariko Harada-Shiba, Yutaka Ishibashi, Tatsuro Ishida, Yasushi Ishigaki, Daijiro Kabata, Yasuki Kihara, Satoshi Kurisu, Daisaku Masuda, Kota Matsuki, Takeshi Matsumura, Kenta Mori, Tomoko Nakagami, Masamitsu Nakazato, Satsuki Taniuchi, Hiroaki Ueno, Shizuya Yamashita, Hisako Yoshida, Hiroyuki Tsutsui, Tetsuo Shoji

  Apr. 2023, Journal of atherosclerosis and thrombosis, 30(12) (12), 1766 - 1777, English, Domestic magazine

  [Refereed]

  Scientific journal


• Reduced incidence of cardiovascular disease in patients with type 2 diabetes through the integrated improvement of diabetes care by comparing two prospective observational cohorts in real-world clinical practice (JDDM 72).

  Hiroki Yokoyama, Shin-Ichi Araki, Koichi Kawai, Katsuya Yamazaki, Osamu Tomonaga, Hajime Maeda, Masafumi Ohtaki, Hiromi Obata, Hirohito Sone, Daijiro Kabata, Ayumi Shintani, Hiroshi Maegawa

  Apr. 2023, Diabetes research and clinical practice, 202, 110674 - 110674, English, International magazine

  [Refereed]

  Scientific journal


• Sepsis-related coagulopathy treatment based on the disseminated intravascular coagulation diagnostic criteria: a post-hoc analysis of a prospective multicenter observational study.

  Takeshi Wada, Kazuma Yamakawa, Daijiro Kabata, Toshikazu Abe, Seitaro Fujishima, Shigeki Kushimoto, Toshihiko Mayumi, Hiroshi Ogura, Daizoh Saitoh, Atsushi Shiraishi, Yasuhiro Otomo, Satoshi Gando

  Mar. 2023, Journal of intensive care, 11(1) (1), 8 - 8, English, International magazine

  [Refereed]

  Scientific journal


• Decreased thymic output predicts progression of chronic kidney disease

  Kenichiro Iio, Daijiro Kabata, Rei Iio, Shinichi Shibamoto, Yuuki Watanabe, Masashi Morita, Yosuke Imai, Masaki Hatanaka, Hiroki Omori, Yoshitaka Isaka

  Feb. 2023, IMMUNITY & AGEING, 20(1) (1), 8 - 8, English, International magazine

  [Refereed]

  Scientific journal


• Association between Familial Hypercholesterolemia and Serum Levels of Cholesterol Synthesis and Absorption Markers: The CACHE Study FH Analysis.

  Kota Matsuki, Mariko Harada-Shiba, Mika Hori, Masatsune Ogura, Yusuke Akiyama, Hisako Fujii, Yutaka Ishibashi, Tatsuro Ishida, Yasushi Ishigaki, Daijiro Kabata, Yasuki Kihara, Kazuhiko Kotani, Satoshi Kurisu, Daisaku Masuda, Tetsuya Matoba, Takeshi Matsumura, Kenta Mori, Tomoko Nakagami, Masamitsu Nakazato, Satsuki Taniuchi, Hiroaki Ueno, Shizuya Yamashita, Hiroshi Yoshida, Hisako Yoshida, Tetsuo Shoji

  Jan. 2023, Journal of atherosclerosis and thrombosis, 30(9) (9), 1152 - 1164, English, Domestic magazine

  [Refereed]

  Scientific journal


• Real-world evidence on levodopa dose escalation in patients with Parkinson's disease treated with istradefylline.

  Nobutaka Hattori, Daijiro Kabata, Shinji Asada, Tomoyuki Kanda, Takanobu Nomura, Ayumi Shintani, Akihisa Mori

  2023, PloS one, 18(12) (12), e0269969, English, International magazine

  [Refereed]

  Scientific journal


• Serum Values of Cholesterol Absorption and Synthesis Biomarkers in Japanese Healthy Subjects: The CACHE Study HEALTHY Analysis

  Yutaka Ishibashi, Hiroshi Yoshida, Kazuhiko Kotani, Yusuke Akiyama, Hisako Fujii, Mariko Harada-Shiba, Tatsuro Ishida, Yasushi Ishigaki, Daijiro Kabata, Yasuki Kihara, Satoshi Kurisu, Daisaku Masuda, Tetsuya Matoba, Kota Matsuki, Takeshi Matsumura, Kenta Mori, Tomoko Nakagami, Masamitsu Nakazato, Satsuki Taniuchi, Hiroaki Ueno, Shizuya Yamashita, Shozo Yano, Hisako Yoshida, Shoji Tetsuo

  2023, Journal of Atherosclerosis and Thrombosis, 30(10) (10), 1336 - 1349, English, Domestic magazine

  [Refereed]

  Scientific journal


• Surgical Outcomes for Hepatocellular Carcinoma in Patients with Child-Pugh Class B: a Retrospective Multicenter Study.

  Shogo Tanaka, Takehiro Noda, Koji Komeda, Hisashi Kosaka, Hiroya Iida, Masaki Ueno, Daisuke Hokuto, Hisashi Ikoma, Takuya Nakai, Daijiro Kabata, Hiroji Shinkawa, Shogo Kobayashi, Fumitoshi Hirokawa, Haruki Mori, Shinya Hayami, Ryo Morimura, Masataka Matsumoto, Takeaki Ishizawa, Shoji Kubo, Masaki Kaibori

  Dec. 2022, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 27(2) (2), 283 - 295, English, International magazine

  [Refereed]

  Scientific journal


• Associations of time-dependent changes in phosphorus levels with cardiovascular diseases in patients undergoing hemodialysis: results from the Japan Dialysis Active Vitamin D (J-DAVID) randomized clinical trial.

  Eri Koshi-Ito, Daijo Inaguma, Haruka Ishii, Yukio Yuzawa, Daijiro Kabata, Ayumi Shintani, Masaaki Inaba, Masanori Emoto, Katsuhito Mori, Tomoaki Morioka, Shinya Nakatani, Tetsuo Shoji

  Dec. 2022, Clinical kidney journal, 15(12) (12), 2281 - 2291, English, International magazine

  [Refereed]

  Scientific journal


• Relationship between Diabetes Mellitus and Serum Lathosterol and Campesterol Levels: The CACHE Study DM Analysis.

  Takeshi Matsumura, Yasushi Ishigaki, Tomoko Nakagami, Yusuke Akiyama, Yutaka Ishibashi, Tatsuro Ishida, Hisako Fujii, Mariko Harada-Shiba, Daijiro Kabata, Yasuki Kihara, Kazuhiko Kotani, Satoshi Kurisu, Daisaku Masuda, Tetsuya Matoba, Kota Matsuki, Kenta Mori, Masamitsu Nakazato, Satsuki Taniuchi, Hiroaki Ueno, Shizuya Yamashita, Hiroshi Yoshida, Hisako Yoshida, Tetsuo Shoji

  Sep. 2022, Journal of atherosclerosis and thrombosis, 30(7) (7), 735 - 753, English, Domestic magazine

  [Refereed]

  Scientific journal


• Effects of alfacalcidol on cardiovascular outcomes according to alkaline phosphatase levels in the J-DAVID trial.

  Tatsufumi Oka, Yusuke Sakaguchi, Yoshitaka Isaka, Haruka Ishii, Daijiro Kabata, Ayumi Shintani, Shinya Nakatani, Tomoaki Morioka, Katsuhito Mori, Masaaki Inaba, Masanori Emoto, Tetsuo Shoji

  Sep. 2022, Scientific reports, 12(1) (1), 15463 - 15463, English, International magazine

  [Refereed]

  Scientific journal


• Early Atrial Tachyarrhythmia Recurrence Predicts Late Atrial Tachyarrhythmia Recurrence After the Cryo-Maze Procedure - An Observational Study.

  Kimito Minami, Masahiro Kazawa, Takashi Kakuta, Satsuki Fukushima, Tomoyuki Fujita, Daijiro Kabata, Yoshihiko Ohnishi

  Aug. 2022, Circulation journal : official journal of the Japanese Circulation Society, 87(1) (1), 76 - 83, English, Domestic magazine

  [Refereed]

  Scientific journal


• Deep Learning–Based Time-to-Death Prediction Model for COVID-19 Patients Using Clinical Data and Chest Radiographs

  Toshimasa Matsumoto, Shannon Leigh Walston, Michael Walston, Daijiro Kabata, Yukio Miki, Masatsugu Shiba, Daiju Ueda

  Aug. 2022, Journal of Digital Imaging, 36(1) (1), 1 - 11, English, International magazine

  [Refereed]

  Scientific journal


• Laparoscopic liver resection reduces postoperative infection in patients with hepatocellular carcinoma: a propensity score-based analysis.

  Daisuke Shirai, Hiroji Shinkawa, Daijiro Kabata, Shigekazu Takemura, Shogo Tanaka, Ryosuke Amano, Kenjiro Kimura, Go Ohira, Kohei Nishio, Jun Tauchi, Masahiko Kinoshita, Shoji Kubo

  Jul. 2022, Surgical endoscopy, 36(12) (12), 9194 - 9203, English, International magazine

  [Refereed]

  Scientific journal


• Age-related differences in the survival benefit of the administration of antithrombin, recombinant human thrombomodulin, or their combination in sepsis.

  Takeshi Wada, Kazuma Yamakawa, Daijiro Kabata, Toshikazu Abe, Hiroshi Ogura, Atsushi Shiraishi, Daizoh Saitoh, Shigeki Kushimoto, Seitaro Fujishima, Toshihiko Mayumi, Toru Hifumi, Yasukazu Shiino, Taka-Aki Nakada, Takehiko Tarui, Yasuhiro Otomo, Kohji Okamoto, Yutaka Umemura, Joji Kotani, Yuichiro Sakamoto, Junichi Sasaki, Shin-Ichiro Shiraishi, Kiyotsugu Takuma, Ryosuke Tsuruta, Akiyoshi Hagiwara, Tomohiko Masuno, Naoshi Takeyama, Norio Yamashita, Hiroto Ikeda, Masashi Ueyama, Satoshi Fujimi, Satoshi Gando

  Jun. 2022, Scientific reports, 12(1) (1), 9304 - 9304, English, International magazine

  [Refereed]

  Scientific journal


• METABOLIC SYNDROME AND LONGITUDINAL RISK OF RENAL AND CARDIOVASCULAR EVENTS IN RENAL TRANSPLANT RECIPIENTS: A SINGLE CENTER STUDY IN JAPAN

  Toshihide Naganuma, Daijiro Kabata, Tomoaki Iwai, Yoshiaki Takemoto, Junji Uchida

  May 2022, NEPHROLOGY DIALYSIS TRANSPLANTATION, 37, I687 - I687, English

  [Refereed]


• Response to correspondence concerning "Association between kidney function and intracerebral hematoma volume".

  Yasufumi Gon, Daijiro Kabata, Hideki Mochizuki

  May 2022, Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 99, 390 - 391, English, International magazine

  [Refereed]


• Prediction Model of Extubation Outcomes in Critically Ill Patients: A Multicenter Prospective Cohort Study

  Aiko Tanaka, Daijiro Kabata, Osamu Hirao, Junko Kosaka, Nana Furushima, Yuichi Maki, Akinori Uchiyama, Moritoki Egi, Ayumi Shintani, Hiroshi Morimatsu, Satoshi Mizobuchi, Yoshifumi Kotake, Yuji Fujino

  May 2022, JOURNAL OF CLINICAL MEDICINE, 11(9) (9), English, International magazine

  [Refereed]

  Scientific journal


• Trends in glycemic control in patients with insulin therapy compared with non-insulin or no drugs in type 2 diabetes in Japan: a long-term view of real-world treatment between 2002 and 2018 (JDDM 66)

  Hiroki Yokoyama, Shin-ichi Araki, Katsuya Yamazaki, Koichi Kawai, Shin-Ichiro Shirabe, Mariko Oishi, Azuma Kanatsuka, Noriharu Yagi, Daijiro Kabata, Ayumi Shintani, Hiroshi Maegawa

  May 2022, BMJ OPEN DIABETES RESEARCH & CARE, 10(3) (3), English, International magazine

  [Refereed]

  Scientific journal


• Maskless 2-Dimensional Digital Subtraction Angiography Generation Model for Abdominal Vasculature using Deep Learning.

  Hiroki Yonezawa, Daiju Ueda, Akira Yamamoto, Ken Kageyama, Shannon Leigh Walston, Takehito Nota, Kazuki Murai, Satoyuki Ogawa, Etsuji Sohgawa, Atsushi Jogo, Daijiro Kabata, Yukio Miki

  Mar. 2022, Journal of vascular and interventional radiology : JVIR, 33(7) (7), 845 - 851, English, International magazine

  [Refereed]

  Scientific journal


• Association of Kidney Function with Serum Levels of Cholesterol Absorption and Synthesis Markers: The CACHE Study CKD Analysis.

  Tetsuo Shoji, Yusuke Akiyama, Hisako Fujii, Mariko Harada-Shiba, Yutaka Ishibashi, Tatsuro Ishida, Yasushi Ishigaki, Daijiro Kabata, Yasuki Kihara, Kazuhiko Kotani, Satoshi Kurisu, Daisaku Masuda, Tetsuya Matoba, Kota Matsuki, Takeshi Matsumura, Kenta Mori, Tomoko Nakagami, Masamitsu Nakazato, Satsuki Taniuchi, Hiroaki Ueno, Shizuya Yamashita, Hisako Yoshida, Hiroshi Yoshida

  Mar. 2022, Journal of atherosclerosis and thrombosis, 29(12) (12), 1835 - 1848, English, Domestic magazine

  [Refereed]

  Scientific journal


• Estimating the treatment effect with propensity score when the effect varies by patient characteristics: A case study and simulation

  Daijiro Kabata, Ayumi Shintani

  Informa UK Limited, Mar. 2022, Communications in Statistics - Case Studies, Data Analysis and Applications, 1 - 13

  [Refereed]

  Scientific journal


• Development and validation of a deep learning model for detection of breast cancers in mammography from multi-institutional datasets

  Daiju Ueda, Akira Yamamoto, Naoyoshi Onoda, Tsutomu Takashima, Satoru Noda, Shinichiro Kashiwagi, Tamami Morisaki, Shinya Fukumoto, Masatsugu Shiba, Mina Morimura, Taro Shimono, Ken Kageyama, Hiroyuki Tatekawa, Kazuki Murai, Takashi Honjo, Akitoshi Shimazaki, Daijiro Kabata, Yukio Miki

  Mar. 2022, PLOS ONE, 17(3) (3), e0265751, English, International magazine

  [Refereed]

  Scientific journal


• Association between kidney function and intracerebral hematoma volume.

  Yasufumi Gon, Daijiro Kabata, Hideki Mochizuki

  Feb. 2022, Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 96, 101 - 106, English, International magazine

  [Refereed]

  Scientific journal


• Pain at the First Post-hemorrhoidectomy Defecation Is Associated with Stool Form.

  Takaaki Yano, Daijiro Kabata, Seiichi Kimura

  2022, Journal of the anus, rectum and colon, 6(3) (3), 168 - 173, English, Domestic magazine

  [Refereed]

  Scientific journal


• Dialysate calcium, alfacalcidol, and clinical outcomes: A post-hoc analysis of the J-DAVID trial.

  Kunitoshi Iseki, Daijiro Kabata, Tetsuo Shoji, Masaaki Inaba, Masanori Emoto, Katsuhito Mori, Tomoaki Morioka, Shinya Nakatani, Ayumi Shintani

  2022, PloS one, 17(9) (9), e0273195, English, International magazine

  [Refereed]

  Scientific journal


• Association of antithrombin with development of trauma-induced disseminated intravascular coagulation and outcomes.

  Takeshi Wada, Atsushi Shiraishi, Satoshi Gando, Daijiro Kabata, Kazuma Yamakawa, Seitaro Fujishima, Daizoh Saitoh, Shigeki Kushimoto, Hiroshi Ogura, Toshikazu Abe, Toshihiko Mayumi, Yasuhiro Otomo

  2022, Frontiers in immunology, 13, 1026163 - 1026163, English, International magazine

  [Refereed]

  Scientific journal


• Ivermectin administration is associated with lower gastrointestinal complications and greater ventilator-free days in ventilated patients with COVID-19: A propensity score analysis.

  Kentaro Shimizu, Haruhiko Hirata, Daijiro Kabata, Natsuko Tokuhira, Moe Koide, Akiko Ueda, Jotaro Tachino, Ayumi Shintani, Akinori Uchiyama, Yuji Fujino, Hiroshi Ogura

  Dec. 2021, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 28(4) (4), 548 - 553, English, International magazine

  [Refereed]

  Scientific journal


• Impact of laparoscopic parenchyma-sparing resection of lesions in the right posterosuperior liver segments on surgical outcomes: A multicenter study based on propensity score analysis.

  Hiroji Shinkawa, Fumitoshi Hirokawa, Masaki Kaibori, Daijiro Kabata, Takeo Nomi, Masaki Ueno, Hisashi Ikoma, Takuya Nakai, Hiroya Iida, Shogo Tanaka, Koji Komeda, Hisashi Kosaka, Daisuke Hokuto, Shinya Hayami, Ryo Morimura, Masataka Matsumoto, Hiromitsu Maehira, Shigekazu Takemura, Shoji Kubo

  Dec. 2021, Surgery, 171(5) (5), 1311 - 1319, English, International magazine

  [Refereed]

  Scientific journal


• Variable selection in double/debiased machine learning for causal inference: an outcome-adaptive approach

  Daijiro Kabata, Mototsugu Shintani

  Lead, Nov. 2021, Communications in Statistics - Simulation and Computation, English

  [Refereed]

  Scientific journal


• Impact of Advancing Age on the Status and Risk of Postoperative Infections After Liver Resection.

  Masahiko Kinoshita, Hiroji Shinkawa, Daijiro Kabata, Shogo Tanaka, Shigekazu Takemura, Ryosuke Amano, Kenjiro Kimura, Go Ohira, Kohei Nishio, Shoji Kubo

  Nov. 2021, World journal of surgery, 45(11) (11), 3386 - 3394, English, International magazine

  [Refereed]

  Scientific journal


• Artificial intelligence-supported lung cancer detection by multi-institutional readers with multi-vendor chest radiographs: a retrospective clinical validation study.

  Daiju Ueda, Akira Yamamoto, Akitoshi Shimazaki, Shannon Leigh Walston, Toshimasa Matsumoto, Nobuhiro Izumi, Takuma Tsukioka, Hiroaki Komatsu, Hidetoshi Inoue, Daijiro Kabata, Noritoshi Nishiyama, Yukio Miki

  Oct. 2021, BMC cancer, 21(1) (1), 1120 - 1120, English, International magazine

  [Refereed]

  Scientific journal


• Association Between Sternotomy Versus Thoracotomy and the Prevalence and Severity of Chronic Postsurgical Pain After Mitral Valve Repair: An Observational Cohort Study.

  Kimito Minami, Daijiro Kabata, Takashi Kakuta, Satsuki Fukushima, Tomoyuki Fujita, Kenji Yoshitani, Yoshihiko Ohnishi

  Oct. 2021, Journal of cardiothoracic and vascular anesthesia, 35(10) (10), 2937 - 2944, English, International magazine

  [Refereed]

  Scientific journal


• A Double-Blind, Placebo-Controlled Study of Ultrasound-Guided Pulsed Radiofrequency Treatment of the Saphenous Nerve for Refractory Osteoarthritis-Associated Knee Pain.

  Hironobu Uematsu, Seiichi Osako, Saya Hakata, Daijiro Kabata, Ayumi Shintani, Daiki Kawazoe, Kiyonori Mizuno, Yuji Fujino, Yoichi Matsuda

  Sep. 2021, Pain physician, 24(6) (6), E761-E769 - E769, English, International magazine

  [Refereed]

  Scientific journal


• The Prognostic Impact of Tumor Differentiation on Recurrence and Survival after Resection of Hepatocellular Carcinoma Is Dependent on Tumor Size.

  Hiroji Shinkawa, Shogo Tanaka, Daijiro Kabata, Shigekazu Takemura, Ryosuke Amano, Kenjiro Kimura, Masahiko Kinoshita, Shoji Kubo

  Sep. 2021, Liver cancer, 10(5) (5), 461 - 472, English, International magazine

  [Refereed]

  Scientific journal


• Impact of stroke history on the presence of cerebral microbleeds in hemodialysis patients.

  Toshihide Naganuma, Daijiro Kabata, Yoshiaki Takemoto, Junji Uchida, Ayumi Shintani

  Aug. 2021, BMC neurology, 21(1) (1), 311 - 311, English, International magazine

  [Refereed]

  Scientific journal


• U-Shaped Association Between Intraoperative Net Fluid Balance and Risk of Postoperative Recurrent Atrial Tachyarrhythmia Among Patients Undergoing the Cryo-Maze Procedure: An Observational Study.

  Kimito Minami, Daijiro Kabata, Takashi Kakuta, Satsuki Fukushima, Tomoyuki Fujita, Ayumi Shintani, Kenji Yoshitani, Yoshihiko Ohnishi

  Aug. 2021, Journal of cardiothoracic and vascular anesthesia, 35(8) (8), 2392 - 2396, English, International magazine

  [Refereed]

  Scientific journal


• Antiplatelet therapy and future intracerebral hemorrhage in hemodialysis patients with cerebral microbleeds.

  Toshihide Naganuma, Daijiro Kabata, Yoshiaki Takemoto, Junji Uchida, Ayumi Shintani

  Aug. 2021, Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 90, 155 - 160, English, International magazine

  [Refereed]

  Scientific journal


• Deep Learning-based Angiogram Generation Model for Cerebral Angiography without Misregistration Artifacts.

  Daiju Ueda, Yutaka Katayama, Akira Yamamoto, Tsutomu Ichinose, Hironori Arima, Yusuke Watanabe, Shannon L Walston, Hiroyuki Tatekawa, Hirotaka Takita, Takashi Honjo, Akitoshi Shimazaki, Daijiro Kabata, Takao Ichida, Takeo Goto, Yukio Miki

  Jun. 2021, Radiology, 299(3) (3), 675 - 681, English, International magazine

  [Refereed]

  Scientific journal


• Association of the Yips and Musculoskeletal Problems in Highly Skilled Golfers: A Large Scale Epidemiological Study in Japan.

  Yasufumi Gon, Daijiro Kabata, Sadahito Kawamura, Masahito Mihara, Ayumi Shintani, Ken Nakata, Hideki Mochizuki

  May 2021, Sports (Basel, Switzerland), 9(6) (6), English, International magazine

  [Refereed]

  Scientific journal


• Cinacalcet may suppress kidney enlargement in hemodialysis patients with autosomal dominant polycystic kidney disease.

  Shinya Nakatani, Kozo Nishide, Senji Okuno, Eiji Ishimura, Daijiro Kabata, Fumiyuki Morioka, Yuri Machiba, Hideki Uedono, Akihiro Tsuda, Shigeichi Shoji, Masaaki Inaba, Katsuhito Mori, Tomoyuki Yamakawa, Masanori Emoto

  May 2021, Scientific reports, 11(1) (1), 10014 - 10014, English, International magazine

  [Refereed]

  Scientific journal


• Assessing liver stiffness with conventional cut-off values overestimates liver fibrosis staging in patients who received the Fontan procedure.

  Yuki Cho, Daijiro Kabata, Eiji Ehara, Akira Yamamoto, Tatsuki Mizuochi, Sotaro Mushiake, Hironori Kusano, Yuko Kuwae, Tsugutoshi Suzuki, Sawako Uchida-Kobayashi, Hiroyasu Morikawa, Yuga Amano-Teranishi, Kiyohide Kioka, Atsushi Jogo, Yoshiharu Isoura, Takashi Hamazaki, Yosuke Murakami, Daisuke Tokuhara

  May 2021, Hepatology research : the official journal of the Japan Society of Hepatology, 51(5) (5), 593 - 602, English, International magazine

  [Refereed]

  Scientific journal


• Multivariate analysis of causal factors influencing accuracy of guided implant surgery for partial edentulism: a retrospective clinical study.

  Atsushi Matsumura, Tamaki Nakano, Shinji Ono, Akihiro Kaminaka, Hirofumi Yatani, Daijiro Kabata

  Apr. 2021, International journal of implant dentistry, 7(1) (1), 28 - 28, English, International magazine

  [Refereed]

  Scientific journal


• Gender-specific analysis for the association between trunk muscle mass and spinal pathologies.

  Yusuke Hori, Masatoshi Hoshino, Kazuhide Inage, Masayuki Miyagi, Shinji Takahashi, Shoichiro Ohyama, Akinobu Suzuki, Tadao Tsujio, Hidetomi Terai, Sho Dohzono, Ryuichi Sasaoka, Hiromitsu Toyoda, Minori Kato, Akira Matsumura, Takashi Namikawa, Masahiko Seki, Kentaro Yamada, Hasibullah Habibi, Hamidullah Salimi, Masaomi Yamashita, Tomonori Yamauchi, Takeo Furuya, Sumihisa Orita, Satoshi Maki, Yasuhiro Shiga, Masahiro Inoue, Gen Inoue, Hisako Fujimaki, Kosuke Murata, Ayumu Kawakubo, Daijiro Kabata, Ayumi Shintani, Seiji Ohtori, Masashi Takaso, Hiroaki Nakamura

  Apr. 2021, Scientific reports, 11(1) (1), 7816 - 7816, English, International magazine

  [Refereed]

  Scientific journal


• Comparative Effects of Etelcalcetide and Maxacalcitol on Serum Calcification Propensity in Secondary Hyperparathyroidism: A Randomized Clinical Trial.

  Tetsuo Shoji, Shinya Nakatani, Daijiro Kabata, Katsuhito Mori, Ayumi Shintani, Hisako Yoshida, Kanae Takahashi, Keiko Ota, Hisako Fujii, Shinichiro Ueda, Shinichi Nishi, Tatsuya Nakatani, Minoru Yoshiyama, Kiyoshi Goto, Takayoshi Hamada, Masahito Imanishi, Eiji Ishimura, Sosuke Kagitani, Yoshikazu Kato, Yasuro Kumeda, Kiyoshi Maekawa, Takayasu Matsumura, Harumi Nagayama, Yasue Obi, Yoshiteru Ohno, Yoshinori Sai, Mayumi Sakurai, Satoshi Sasaki, Kaori Shidara, Shigeichi Shoji, Yoshihiro Tsujimoto, Kenjiro Yamakawa, Hideaki Yasuda, Shozo Yodoi, Masaaki Inaba, Masanori Emoto

  Apr. 2021, Clinical journal of the American Society of Nephrology : CJASN, 16(4) (4), 599 - 612, English, International magazine

  [Refereed]

  Scientific journal


• Effect of Earlier Door-to-CT and Door-to-Bleeding Control in Severe Blunt Trauma: A Retrospective Cohort Study.

  Shuhei Murao, Kazuma Yamakawa, Daijiro Kabata, Takahiro Kinoshita, Yutaka Umemura, Ayumi Shintani, Satoshi Fujimi

  Apr. 2021, Journal of clinical medicine, 10(7) (7), English, International magazine

  [Refereed]

  Scientific journal


• Clinical and Genetic Characteristics of Patients with Mild Hyperphenylalaninemia Identified by Newborn Screening Program in Japan.

  Shino Odagiri, Daijiro Kabata, Shogo Tomita, Satoshi Kudo, Tomoko Sakaguchi, Noriko Nakano, Kouji Yamamoto, Haruo Shintaku, Takashi Hamazaki

  Mar. 2021, International journal of neonatal screening, 7(1) (1), English, International magazine

  [Refereed]

  Scientific journal


• Oxidative Stress and Inflammation as Predictors of Mortality and Cardiovascular Events in Hemodialysis Patients: The DREAM Cohort.

  Keyaki Sasaki, Tetsuo Shoji, Daijiro Kabata, Ayumi Shintani, Yujiro Okute, Shoko Tsuchikura, Naoko Shimomura, Yoshihiro Tsujimoto, Shinya Nakatani, Katsuhito Mori, Atsushi Shioi, Masaaki Inaba, Masanori Emoto

  Mar. 2021, Journal of atherosclerosis and thrombosis, 28(3) (3), 249 - 260, English, Domestic magazine

  [Refereed]

  Scientific journal


• Effect of long-term rigid gas-permeable contact lens wear on keratoconus progression.

  Satoko Araki, Shizuka Koh, Daijiro Kabata, Ryota Inoue, Daichi Morii, Naoyuki Maeda, Ayumi Shintani, Vishal Jhanji, Kohji Nishida

  Feb. 2021, The British journal of ophthalmology, 105(2) (2), 186 - 190, English, International magazine

  [Refereed]

  Scientific journal


• Chest physical therapy reduces pneumonia following inhalation injury.

  Takatsugu Kubo, Akinori Osuka, Daijiro Kabata, Masahiko Kimura, Kazuyuki Tabira, Hiroshi Ogura

  Feb. 2021, Burns : journal of the International Society for Burn Injuries, 47(1) (1), 198 - 205, English, International magazine

  [Refereed]

  Scientific journal


• Impact of background factors on outcomes of pharmacological therapy for chronic low back pain: A nationwide multicenter prospective study.

  Shiro Imagama, Hideki Murakami, Takashi Kaito, Yukihiro Matsuyama, Toshihiko Yamashita, Mamoru Kawakami, Kazuhisa Takahashi, Munehito Yoshida, Seiji Ohtori, Toshihiko Taguchi, Hirotaka Haro, Hiroshi Taneichi, Masashi Yamazaki, Gen Inoue, Kotaro Nishida, Hiroshi Yamada, Daijiro Kabata, Ayumi Shintani, Motoki Iwasaki, Manabu Ito, Naohisa Miyakoshi, Kazuo Yonenobu, Tomoyuki Takura, Joji Mochida

  Jan. 2021, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 26(1) (1), 92 - 102, English, Domestic magazine

  [Refereed]

  Scientific journal


• Safety and Efficacy of Tandem Hemodialysis and Selective Plasma Exchange in Pretransplant Desensitization of ABO-Incompatible Kidney Transplantation.

  Ako Hanaoka, Toshihide Naganuma, Daijiro Kabata, Daichi Morii, Yoshiaki Takemoto, Junji Uchida, Ayumi Shintani

  2021, Blood purification, 50(6) (6), 829 - 836, English, International magazine

  [Refereed]

  Scientific journal


• Crosstalk Between NDP52 and LUBAC in Innate Immune Responses, Cell Death, and Xenophagy.

  Hirohisa Miyashita, Daisuke Oikawa, Seigo Terawaki, Daijiro Kabata, Ayumi Shintani, Fuminori Tokunaga

  2021, Frontiers in immunology, 12, 635475 - 635475, English, International magazine

  [Refereed]

  Scientific journal


• Comparison of the Effectiveness of Pharmacological Treatments for Patients with Chronic Low Back Pain: A Nationwide, Multicenter Study in Japan.

  Gen Inoue, Takashi Kaito, Yukihiro Matsuyama, Toshihiko Yamashita, Mamoru Kawakami, Kazuhisa Takahashi, Munehito Yoshida, Shiro Imagama, Seiji Ohtori, Toshihiko Taguchi, Hirotaka Haro, Hiroshi Taneichi, Masashi Yamazaki, Kotaro Nishida, Hiroshi Yamada, Daijiro Kabata, Ayumi Shintani, Motoki Iwasaki, Manabu Ito, Naohisa Miyakoshi, Hideki Murakami, Kazuo Yonenobu, Tomoyuki Takura, Joji Mochida

  2021, Spine surgery and related research, 5(4) (4), 252 - 263, English, Domestic magazine

  [Refereed]

  Scientific journal


• Multivariate analysis of the influence of prosthodontic factors on peri-implant bleeding index and marginal bone level in a molar site: A cross-sectional study.

  Masaki Inoue, Tamaki Nakano, Takuya Shimomoto, Daijiro Kabata, Ayumi Shintani, Hirofumi Yatani

  Dec. 2020, Clinical implant dentistry and related research, 22(6) (6), 713 - 722, English, International magazine

  [Refereed]

  Scientific journal


• A Prospective, Randomized, Open-Label Trial of Early versus Late Favipiravir Therapy in Hospitalized Patients with COVID-19.

  Yohei Doi, Masaya Hibino, Ryota Hase, Michiko Yamamoto, Yu Kasamatsu, Masahiro Hirose, Yoshikazu Mutoh, Yoshito Homma, Masaki Terada, Taku Ogawa, Fumihiro Kashizaki, Toshihiko Yokoyama, Hayato Koba, Hideki Kasahara, Kazuhisa Yokota, Hideaki Kato, Junichi Yoshida, Toshiyuki Kita, Yasuyuki Kato, Tadashi Kamio, Nobuhiro Kodama, Yujiro Uchida, Nobuhiro Ikeda, Masahiro Shinoda, Atsushi Nakagawa, Hiroki Nakatsumi, Tomoya Horiguchi, Mitsunaga Iwata, Akifumi Matsuyama, Sumi Banno, Takenao Koseki, Mayumi Teramachi, Masami Miyata, Shigeru Tajima, Takahiro Maeki, Eri Nakayama, Satoshi Taniguchi, Chang Kweng Lim, Masayuki Saijo, Takumi Imai, Hisako Yoshida, Daijiro Kabata, Ayumi Shintani, Yukio Yuzawa, Masashi Kondo

  Nov. 2020, Antimicrobial agents and chemotherapy, 64(12) (12), English, International magazine

  [Refereed]

  Scientific journal


• Identifying Septic Shock Populations Benefitting From Polymyxin B Hemoperfusion: A Prospective Cohort Study Incorporating a Restricted Cubic Spline Regression Model.

  Hidekazu Nakata, Kazuma Yamakawa, Daijiro Kabata, Yutaka Umemura, Hiroshi Ogura, Satoshi Gando, Ayumi Shintani, Atsushi Shiraishi, Daizoh Saitoh, Seitaro Fujishima, Toshihiko Mayumi, Shigeki Kushimoto, Toshikazu Abe, Yasukazu Shiino, Taka-Aki Nakada, Takehiko Tarui, Toru Hifumi, Yasuhiro Otomo, Kohji Okamoto, Joji Kotani, Yuichiro Sakamoto, Junichi Sasaki, Shin-Ichiro Shiraishi, Kiyotsugu Takuma, Ryosuke Tsuruta, Akiyoshi Hagiwara, Tomohiko Masuno, Naoshi Takeyama, Norio Yamashita, Hiroto Ikeda, Masashi Ueyama, Satoshi Fujimi

  Nov. 2020, Shock (Augusta, Ga.), 54(5) (5), 667 - 674, English, International magazine

  [Refereed]

  Scientific journal


• Comparison of 1-year recurrence-free survival between sevoflurane and propofol use for general anesthesia management in primary breast cancer surgery.

  Shinnosuke Shiono, Sho C Shibata, Daijiro Kabata, Ayumi Shintani, Takehiko Ikeda, Yuji Fujino

  Oct. 2020, Journal of anesthesia, 34(5) (5), 694 - 701, English, Domestic magazine

  [Refereed]

  Scientific journal


• Hematological Abnormalities and Malnutrition Mediate Pathway between Cancer and Outcomes in Ischemic Stroke Patients.

  Yasufumi Gon, Daijiro Kabata, Tomohiro Kawano, Hideaki Kanki, Kenichi Todo, Tsutomu Sasaki, Ayumi Shintani, Hideki Mochizuki

  Aug. 2020, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 29(8) (8), 104943 - 104943, English, International magazine

  [Refereed]

  Scientific journal


• Positive correlation between pancreatic volume and post-endoscopic retrograde cholangiopancreatography pancreatitis.

  Hirotsugu Maruyama, Masatsugu Shiba, Yuki Ishikawa-Kakiya, Kunihiro Kato, Masaki Ominami, Shusei Fukunaga, Koji Otani, Shuhei Hosomi, Fumio Tanaka, Noriko Kamata, Koichi Taira, Yasuaki Nagami, Hirokazu Yamagami, Tetsuya Tanigawa, Toshio Watanabe, Akira Yamamoto, Daijiro Kabata, Ayumi Shintani, Yasuhiro Fujiwara

  May 2020, Journal of gastroenterology and hepatology, 35(5) (5), 769 - 776, English, International magazine

  [Refereed]

  Scientific journal


• Predictive factors of outcome of selective retina therapy for diabetic macular edema.

  Manabu Yamamoto, Yoko Miura, Kumiko Hirayama, Takeya Kohno, Daijiro Kabata, Dirk Theisen-Kunde, Ralf Brinkmann, Shigeru Honda

  May 2020, International ophthalmology, 40(5) (5), 1221 - 1232, English, International magazine

  [Refereed]

  Scientific journal


• Frailty is associated with dialysis duration before transplantation in kidney transplant recipients: A Japanese single-center cross-sectional study.

  Akihiro Kosoku, Junji Uchida, Tomoaki Iwai, Hisao Shimada, Kazuya Kabei, Shunji Nishide, Keiko Maeda, Daijiro Kabata, Ayumi Shintani, Tatsuya Nakatani

  May 2020, International journal of urology : official journal of the Japanese Urological Association, 27(5) (5), 408 - 414, English, International magazine

  [Refereed]

  Scientific journal


• Factors associated with diabetic polyneuropathy-related sensory symptoms and signs in patients with polyneuropathy: A cross-sectional Japanese study (JDDM 52) using a non-linear model.

  Hiroki Yokoyama, Toshinaga Tsuji, Shinji Hayashi, Daijiro Kabata, Ayumi Shintani

  Mar. 2020, Journal of diabetes investigation, 11(2) (2), 450 - 457, English, Domestic magazine

  [Refereed]

  Scientific journal


• Selective plasma exchange in ABO-incompatible kidney transplantation: comparison of substitution with albumin and partial substitution with fresh frozen plasma.

  Ako Hanaoka, Toshihide Naganuma, Daijiro Kabata, Yoshiaki Takemoto, Junji Uchida, Tatsuya Nakatani, Ayumi Shintani

  Jan. 2020, Scientific reports, 10(1) (1), 1434 - 1434, English, International magazine

  [Refereed]

  Scientific journal


• Impact of Consultation Length on Satisfaction in Patients with Chronic Low Back Pain: A Nationwide Multicenter Study in Japan.

  Naohisa Miyakoshi, Daisuke Kudo, Yukihiro Matsuyama, Toshihiko Yamashita, Mamoru Kawakami, Kazuhisa Takahashi, Munehito Yoshida, Takashi Kaito, Shiro Imagama, Seiji Ohtori, Toshihiko Taguchi, Hirotaka Haro, Hiroshi Taneichi, Masashi Yamazaki, Gen Inoue, Kotaro Nishida, Hiroshi Yamada, Daijiro Kabata, Ayumi Shintani, Motoki Iwasaki, Manabu Ito, Hideki Murakami, Kazuo Yonenobu, Tomoyuki Takura, Joji Mochida

  2020, Spine surgery and related research, 4(3) (3), 208 - 215, English, Domestic magazine

  [Refereed]

  Scientific journal


• Type and Size of Implanted Bioprosthetic Valve Rather Than Intraoperative Peak Transprosthetic Valvular Velocity Predict Postoperative Midterm Prosthesis-Patient Mismatch in Patients Undergoing Surgical Aortic Valve Replacement.

  Kimito Minami, Daijiro Kabata, Ayumi Shintani, Yorihiko Matsumoto, Naoki Tadokoro, Tomoyuki Fujita, Kenji Yoshitani, Yoshihiko Ohnishi

  Dec. 2019, Journal of cardiothoracic and vascular anesthesia, 33(12) (12), 3264 - 3270, English, International magazine

  [Refereed]

  Scientific journal


• Identifying Sepsis Populations Benefitting from Anticoagulant Therapy: A Prospective Cohort Study Incorporating a Restricted Cubic Spline Regression Model.

  Kazuma Yamakawa, Satoshi Gando, Hiroshi Ogura, Yutaka Umemura, Daijiro Kabata, Ayumi Shintani, Atsushi Shiraishi, Daizoh Saitoh, Seitato Fujishima, Toshihiko Mayumi, Shigeki Kushimoto, Toshikazu Abe, Yasukazu Shiino, Taka-Aki Nakada, Takehiko Tarui, Toru Hifumi, Yasuhiro Otomo, Kohji Okamoto, Joji Kotani, Yuichiro Sakamoto, Junichi Sasaki, Shin-Ichiro Shiraishi, Kiyotsugu Takuma, Ryosuke Tsuruta, Akiyoshi Hagiwara, Tomohiko Masuno, Naoshi Takeyama, Norio Yamashita, Hiroto Ikeda, Masashi Ueyama, Satoshi Fujimi

  Nov. 2019, Thrombosis and haemostasis, 119(11) (11), 1740 - 1751, English, International magazine

  [Refereed]

  Scientific journal


• Translation and validation of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) among Japanese soft contact lens wearers: The J-CLDEQ-8.

  Shizuka Koh, Robin Chalmers, Daijiro Kabata, Ayumi Shintani, Kohji Nishida

  Oct. 2019, Contact lens & anterior eye : the journal of the British Contact Lens Association, 42(5) (5), 533 - 539, English, International magazine

  [Refereed]

  Scientific journal


• Cost-effectiveness analysis of the pharmacological management of chronic low back pain with four leading drugs.

  Takashi Kaito, Yukihiro Matsuyama, Toshihiko Yamashita, Mamoru Kawakami, Kazuhisa Takahashi, Munehito Yoshida, Shiro Imagama, Seiji Ohtori, Toshihiko Taguchi, Hirotaka Haro, Hiroshi Taneichi, Masashi Yamazaki, Gen Inoue, Kotaro Nishida, Hiroshi Yamada, Daijiro Kabata, Ayumi Shintani, Motoki Iwasaki, Manabu Ito, Naohisa Miyakoshi, Hideki Murakami, Kazuo Yonenobu, Tomoyuki Takura, Joji Mochida

  Sep. 2019, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 24(5) (5), 805 - 811, English, Domestic magazine

  [Refereed]

  Scientific journal


• Translation and Validation of the 8-Item Contact Lens Dry Eye Questionnaire (CLDEQ-8) among Japanese Soft Contact Lens Wearers: the J-CLDEQ-8

  Shizuka Koh, Robin Chalmers, Daijiro Kabata, Ayumi Shintani, Kohji Nishida

  Jul. 2019, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 60(9) (9), English

  [Refereed]


• Contemporary outcomes of the concomitant CryoMaze procedure.

  Takashi Kakuta, Satsuki Fukushima, Kimito Minami, Yusuke Shimahara, Takuma Yamasaki, Yorihiko Matsumoto, Kizuku Yamashita, Naonori Kawamoto, Naoki Tadokoro, Daijiro Kabata, Junjiro Kobayashi, Tomoyuki Fujita

  Jul. 2019, Interactive cardiovascular and thoracic surgery, 29(1) (1), 28 - 34, English, International magazine

  [Refereed]

  Scientific journal


• Serum albumin as a risk factor for death in patients with prolonged sepsis: An observational study.

  Ryosuke Takegawa, Daijiro Kabata, Kentaro Shimizu, Saya Hisano, Hiroshi Ogura, Ayumi Shintani, Takeshi Shimazu

  Jun. 2019, Journal of critical care, 51, 139 - 144, English, International magazine

  [Refereed]

  Scientific journal


• Long-term Chronological Changes in Very Asymmetric Keratoconus.

  Shizuka Koh, Ryota Inoue, Naoyuki Maeda, Daijiro Kabata, Ayumi Shintani, Vishal Jhanji, Stephen D Klyce, Kazuichi Maruyama, Kohji Nishida

  May 2019, Cornea, 38(5) (5), 605 - 611, English, International magazine

  [Refereed]

  Scientific journal


• ISSLS PRIZE IN CLINICAL SCIENCE 2019: clinical importance of trunk muscle mass for low back pain, spinal balance, and quality of life-a multicenter cross-sectional study.

  Yusuke Hori, Masatoshi Hoshino, Kazuhide Inage, Masayuki Miyagi, Shinji Takahashi, Shoichiro Ohyama, Akinobu Suzuki, Tadao Tsujio, Hidetomi Terai, Sho Dohzono, Ryuichi Sasaoka, Hiromitsu Toyoda, Minori Kato, Akira Matsumura, Takashi Namikawa, Masahiko Seki, Kentaro Yamada, Hasibullah Habibi, Hamidullah Salimi, Masaomi Yamashita, Tomonori Yamauchi, Takeo Furuya, Sumihisa Orita, Satoshi Maki, Yasuhiro Shiga, Masahiro Inoue, Gen Inoue, Hisako Fujimaki, Kosuke Murata, Ayumu Kawakubo, Daijiro Kabata, Ayumi Shintani, Seiji Ohtori, Masashi Takaso, Hiroaki Nakamura

  May 2019, European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 28(5) (5), 914 - 921, English, International magazine

  [Refereed]

  Scientific journal


• Crosstalk between tumor necrosis factor-alpha signaling and aryl hydrocarbon receptor signaling in nuclear factor -kappa B activation: A possible molecular mechanism underlying the reduced efficacy of TNF-inhibitors in rheumatoid arthritis by smoking.

  Takuro Nii, Kentaro Kuzuya, Daijiro Kabata, Toshihiro Matsui, Atsuko Murata, Takeshi Ohya, Hidetoshi Matsuoka, Takashi Shimizu, Eri Oguro, Yasutaka Okita, Chikako Udagawa, Maiko Yoshimura, Eriko Kudo-Tanaka, Satoru Teshigawara, Yoshinori Harada, Yuji Yoshida, Kentaro Isoda, So-Ichiro Tsuji, Shiro Ohshima, Jun Hashimoto, Ayumi Shintani, Yasuo Takehana, Shigeto Tohma, Yukihiko Saeki

  Mar. 2019, Journal of autoimmunity, 98, 95 - 102, English, International magazine

  [Refereed]

  Scientific journal


• Efficacy of selective plasma exchange as pre-transplant apheresis in ABO-incompatible kidney transplantation

  Ako Hanaoka, Toshihide Naganuma, Yoshiaki Takemoto, Junji Uchida, Tatsuya Nakatani, Daijiro Kabata, Ayumi Shintani

  Feb. 2019, RENAL REPLACEMENT THERAPY, 5(1) (1), English

  [Refereed]

  Scientific journal


• A Multicenter Retrospective Study of Elective Neck Dissection for T1-2N0M0 Tongue Squamous Cell Carcinoma: Analysis Using Propensity Score-Matching.

  Mitsunobu Otsuru, Yoshihide Ota, Souichi Yanamoto, Masaya Okura, Masahiro Umeda, Tadaaki Kirita, Hiroshi Kurita, Michihiro Ueda, Takahide Komori, Nobuhiro Yamakawa, Takahiro Kamata, Takumi Hasegawa, Takahiko Shibahara, Youichi Ohiro, Yoshihiro Yamashita, Kazuma Noguchi, Tadahide Noguchi, Kazunari Karakida, Hiroyuki Naito, Tomonao Aikawa, Tetsuro Yamashita, Daijiro Kabata, Ayumi Shintani

  Feb. 2019, Annals of surgical oncology, 26(2) (2), 555 - 563, English, International magazine

  [Refereed]

  Scientific journal


• Parathyroid hormone and premature thymus ageing in patients with chronic kidney disease.

  Kenichiro Iio, Daijiro Kabata, Rei Iio, Yosuke Imai, Masaki Hatanaka, Hiroki Omori, Yoshihiko Hoshida, Yukihiko Saeki, Ayumi Shintani, Takayuki Hamano, Yoshitaka Isaka, Yutaka Ando

  Jan. 2019, Scientific reports, 9(1) (1), 813 - 813, English, International magazine

  [Refereed]

  Scientific journal


• Usefulness of serum biopterin as a predictive biomarker for childhood asthma control: A prospective cohort study.

  Saki Kasuga, Daijiro Kabata, Tomoko Sakaguchi, Satoshi Kudoh, Satsuki Nishigaki, Yusuke Higa, Shiori Fujikawa, Hiroko Fujitani, Ayumi Shintani, Takashi Hamazaki, Haruo Shintaku

  Jan. 2019, Allergology international : official journal of the Japanese Society of Allergology, 68(1) (1), 96 - 100, English, International magazine

  [Refereed]

  Scientific journal


• Optimal Biopsy Protocol to Evaluate Histological Effectiveness of Proton Pump Inhibitor Therapy in Patients with Eosinophilic Esophagitis.

  Yasuhiro Fujiwara, Atsushi Hashimoto, Risa Uemura, Akinari Sawada, Koji Otani, Fumio Tanaka, Hirokazu Yamagami, Tetsuya Tanigawa, Toshio Watanabe, Daijiro Kabata, Yuko Kuwae, Ayumi Shintani, Masahiko Ohsawa

  2019, Digestion, 100(1) (1), 64 - 71, English, International magazine

  [Refereed]

  Scientific journal


• Hypercalcemia Is a Risk Factor for the Progression of Aortic Calcification in Kidney Transplant Recipients.

  Toshihide Naganuma, Yoshiaki Takemoto, Junji Uchida, Tatsuya Nakatani, Daijiro Kabata, Ayumi Shintani

  2019, Kidney & blood pressure research, 44(4) (4), 823 - 834, English, International magazine

  [Refereed]

  Scientific journal


• Prediction model for cardiovascular events or all-cause mortality in incident dialysis patients.

  Daijo Inaguma, Daichi Morii, Daijiro Kabata, Hiroyuki Yoshida, Akihito Tanaka, Eri Koshi-Ito, Kazuo Takahashi, Hiroki Hayashi, Shigehisa Koide, Naotake Tsuboi, Midori Hasegawa, Ayumi Shintani, Yukio Yuzawa

  2019, PloS one, 14(8) (8), e0221352, English, International magazine

  [Refereed]

  Scientific journal


• Transcatheter Aortic Valve Replacement for Severe Aortic Stenosis Complicated by Sigmoid Septum.

  Kizuku Yamashita, Tomoyuki Fujita, Satsuki Fukushima, Yusuke Shimahara, Yuta Kume, Yorihiko Matsumoto, Naonori Kawamoto, Kimito Minami, Daijiro Kabata, Hideaki Kanzaki, Chisato Izumi, Toshihisa Anzai, Junjiro Kobayashi

  Nov. 2018, Circulation journal : official journal of the Japanese Circulation Society, 82(12) (12), 3090 - 3099, English, Domestic magazine

  [Refereed]

  Scientific journal


• Drug-Coated Balloon Angioplasty in Atherosclerosis Patients With Popliteal Artery Involvement.

  Tomoharu Dohi, Andrej Schmidt, Dierk Scheinert, Yvonne Bausback, Daijiro Kabata, Ayumi Shintani, Yasushi Sakata, Sabine Steiner

  Oct. 2018, Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, 25(5) (5), 581 - 587, English, International magazine

  [Refereed]

  Scientific journal


• Association of prophylactic synbiotics with reduction in diarrhea and pneumonia in mechanically ventilated critically ill patients: A propensity score analysis.

  Kentaro Shimizu, Hiroshi Ogura, Daijiro Kabata, Ayumi Shintani, Osamu Tasaki, Masahiro Ojima, Mitsunori Ikeda, Takeshi Shimazu

  Oct. 2018, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 24(10) (10), 795 - 801, English, International magazine

  [Refereed]

  Scientific journal


• Predictors of postoperative bleeding after vitrectomy for vitreous hemorrhage in patients with diabetic retinopathy.

  Saori Motoda, Nobuhiko Shiraki, Takuma Ishihara, Hirokazu Sakaguchi, Daijiro Kabata, Mitsuyoshi Takahara, Takekazu Kimura, Junji Kozawa, Akihisa Imagawa, Kohji Nishida, Ayumi Shintani, Hiromi Iwahashi, Iichiro Shimomura

  Jul. 2018, Journal of diabetes investigation, 9(4) (4), 940 - 945, English, Domestic magazine

  [Refereed]

  Scientific journal


• Public attitudes in Japan toward participation in whole genome sequencing studies.

  Taketoshi Okita, Noriko Ohashi, Daijiro Kabata, Ayumi Shintani, Kazuto Kato

  Apr. 2018, Human genomics, 12(1) (1), 21 - 21, English, International magazine

  [Refereed]

  Scientific journal


• Recovery of Serum Testosterone Levels and Sexual Function in Patients Treated With Short-term Luteinizing Hormone-releasing Hormone Antagonist as a Neoadjuvant Therapy Before External Radiotherapy for Intermediate-risk Prostate Cancer: Preliminary Prospective Study.

  Takahiro Inoue, Takashi Mizowaki, Daijiro Kabata, Ayumi Shintani, Naoki Terada, Toshinari Yamasaki, Hiromitsu Negoro, Takashi Kobayashi, Kiyonao Nakamura, Haruo Inokuchi, Osamu Ogawa

  Apr. 2018, Clinical genitourinary cancer, 16(2) (2), 135 - 141, English, International magazine

  [Refereed]

  Scientific journal


• Efficacy of a concomitant elemental diet to reduce the loss of response to adalimumab in patients with intractable Crohn's disease.

  Naoko Sugita, Kenji Watanabe, Noriko Kamata, Tomomi Yukawa, Koji Otani, Shuhei Hosomi, Yasuaki Nagami, Fumio Tanaka, Koichi Taira, Hirokazu Yamagami, Tetsuya Tanigawa, Masatsugu Shiba, Toshio Watanabe, Kazunari Tominaga, Daijiro Kabata, Ayumi Shintani, Tetsuo Arakawa, Yasuhiro Fujiwara

  Mar. 2018, Journal of gastroenterology and hepatology, 33(3) (3), 631 - 637, English, International magazine

  [Refereed]

  Scientific journal


• Drug retention and discontinuation reasons between seven biologics in patients with rheumatoid arthritis -The ANSWER cohort study.

  Kosuke Ebina, Motomu Hashimoto, Wataru Yamamoto, Akira Ohnishi, Daijiro Kabata, Toru Hirano, Ryota Hara, Masaki Katayama, Shuzo Yoshida, Koji Nagai, Yonsu Son, Hideki Amuro, Kengo Akashi, Takanori Fujimura, Makoto Hirao, Keiichi Yamamoto, Ayumi Shintani, Atsushi Kumanogoh, Hideki Yoshikawa

  2018, PloS one, 13(3) (3), e0194130, English, International magazine

  [Refereed]

  Scientific journal


• Validation of an algorithm that determines stroke diagnostic code accuracy in a Japanese hospital-based cancer registry using electronic medical records.

  Yasufumi Gon, Daijiro Kabata, Keichi Yamamoto, Ayumi Shintani, Kenichi Todo, Hideki Mochizuki, Manabu Sakaguchi

  Dec. 2017, BMC medical informatics and decision making, 17(1) (1), 157 - 157, English, International magazine

  [Refereed]

  Scientific journal


• Epidemiological and outcome data in Japanese patients with deep vein thrombosis with and without malignancy.

  Kensuke Yokoi, Masahiko Hara, Yasunori Ueda, Keiichi Yamamoto, Keiko Ota, Daijiro Kabata, Tetsuhisa Kitamura, Yasushi Sakata, Ayumi Shintani

  Dec. 2017, Heart and vessels, 32(12) (12), 1469 - 1477, English, Domestic magazine

  [Refereed]

  Scientific journal


• Improving Outcomes of Witnessed Out-of-Hospital Cardiac Arrest After Implementation of International Liaison Committee on Resuscitation 2010 Consensus: A Nationwide Prospective Observational Population-Based Study.

  Hidehiro Kaneko, Masahiko Hara, Kazuki Mizutani, Minoru Yoshiyama, Kensuke Yokoi, Daijiro Kabata, Ayumi Shintani, Tetsuhisa Kitamura

  Aug. 2017, Journal of the American Heart Association, 6(8) (8), English, International magazine

  [Refereed]

  Scientific journal


• Plasma homocysteine and cerebral small vessel disease as possible mediators between kidney and cognitive functions in patients with diabetes mellitus.

  Mika Sonoda, Tetsuo Shoji, Yukinobu Kuwamura, Yujiro Okute, Toshihide Naganuma, Hideaki Shima, Koka Motoyama, Tomoaki Morioka, Katsuhito Mori, Shinya Fukumoto, Atsushi Shioi, Taro Shimono, Hisako Fujii, Daijiro Kabata, Ayumi Shintani, Masanori Emoto, Masaaki Inaba

  Jun. 2017, Scientific reports, 7(1) (1), 4382 - 4382, English, International magazine

  [Refereed]

  Scientific journal


• Ideal Guiding Catheter Position During Bilaterally Engaged Percutaneous Coronary Intervention.

  Kensuke Yokoi, Masahiko Hara, Yasunori Ueda, Satoru Sumitsuji, Masaki Awata, Youssef K Salah, Daijiro Kabata, Ayumi Shintani, Yasushi Sakata

  May 2017, The American journal of cardiology, 119(10) (10), 1518 - 1524, English, International magazine

  [Refereed]

  Scientific journal


• Efficacy and safety of super selective bronchial artery coil embolisation for haemoptysis: a single-centre retrospective observational study.

  Hideo Ishikawa, Masahiko Hara, Misaki Ryuge, Jun Takafuji, Mihoko Youmoto, Masanori Akira, Yukio Nagasaka, Daijiro Kabata, Kouji Yamamoto, Ayumi Shintani

  Feb. 2017, BMJ open, 7(2) (2), e014805, English, International magazine

  [Refereed]

  Scientific journal

• A sensitivity analysis for non-inferiority studies with non-randomised data

  Daijiro Kabata, Takumi Imai

  Lead, 22 Nov. 2025, arXiv


• Generalisable prediction model of surgical case duration: multicentre development and temporal validation

  Daijiro Kabata, Mari Ito, Tokito Koga, Kazuma Yunoki

  Background: Accurate prediction of surgical case duration underpins operating room (OR) scheduling, yet existing models often depend on site- or surgeon-specific inputs and rarely undergo external validation, limiting generalisability. Methods: We undertook a retrospective multicentre study using routinely collected perioperative data from two general hospitals in Japan (development: 1 January 2021-31 December 2023; temporal test: 1 January-31 December 2024). Elective weekday procedures with American Society of Anesthesiologists (ASA) Physical Status 1-4 were included. Pre-specified preoperative predictors comprised surgical context (year, month, weekday, scheduled duration, general anaesthesia indicator, body position) and patient factors (sex, age, body mass index, allergy, infection, comorbidity, ASA). Missing data were addressed by multiple imputation by chained equations. Four learners (elastic-net, generalised additive models, random forest, gradient-boosted trees) were tuned within internal-external cross-validation (IECV; leave-one-cluster-out by centre-year) and combined by stacked generalisation to predict log-transformed duration. Results: We analysed 63,206 procedures (development 45,647; temporal test 17,559). Cluster-specific and pooled errors and calibrations from IECV are provided with consistent performance across centres and years. In the 2024 temporal test cohort, calibration was good (intercept 0.423, 95%CI 0.372 to 0.474; slope 0.921, 95%CI 0.911 to 0.932). Conclusions: A stacked machine-learning model using only widely available preoperative variables achieved accurate, well-calibrated predictions in temporal external validation, supporting transportability across sites and over time. Such general-purpose tools may improve OR scheduling without relying on idiosyncratic inputs.

  Lead, 12 Nov. 2025, arXiv


• Quantifying uncertainty of individualized treatment effects in right-censored survival data: A comparison of Bayesian additive regression trees and causal survival forest

  Daijiro Kabata, Nicholas C. Henderson, Ravi Varadhan

  Estimation of individualized treatment effects (ITE), also known as conditional average treatment effects (CATE), is an active area of methodology development. However, much less attention has been paid to the quantification of uncertainty of ITE/CATE estimates in right-censored survival data. Here we undertake an extensive simulation study to examine the coverage of interval estimates from two popular estimation algorithms, Bayesian additive regression trees (BART) and causal survival forest (CSF). We conducted simulation designs from 3 different settings: first, in a setting where BART was developed for an accelerated failure time model; second, where CSF was developed; and finally, a ``neutral'' simulation taken from a setting where neither BART nor CSF was developed. BART outperformed CSF in all three simulation settings. Both the BART and CSF algorithms involve multiple hyperparameters, and BART credible intervals had better coverage than the CSF confidence intervals under the default values, as well as under optimized values, of these hyperparameters.

  Lead, 06 Apr. 2025


• Double/Debiased Machine Learning for Causal Inference on Survival Function

  Daijiro Kabata, Mototsugu Shintani

  Lead, Elsevier BV, Nov. 2024, Social Science Research Network


• Double/debiased Machine Learning for Causal Inference on Survival Function

  Daijiro Kabata, Mototsugu Shintani

  Lead, May 2024, CSRDA Disucussion Paper, 84


• Diagnostic Performance Comparison between Generative AI and Physicians: A Systematic Review and Meta-Analysis

  Hirotaka Takita, Daijiro Kabata, Shannon L Walston, Hiroyuki Tatekawa, Kenichi Saito, Yasushi Tsujimoto, Yukio Miki, Daiju Ueda

  Abstract Background The rapid advancement of generative artificial intelligence (AI) has led to the wide dissemination of models with exceptional understanding and generation of human language. Their integration into healthcare has shown potential for improving medical diagnostics, yet a comprehensive diagnostic performance evaluation of generative AI models and the comparison of their diagnostic performance with that of physicians has not been extensively explored. Methods In this systematic review and meta-analysis, a comprehensive search of Medline, Scopus, Web of Science, Cochrane Central, and MedRxiv was conducted for studies published from June 2018 through December 2023, focusing on those that validate generative AI models for diagnostic tasks. The risk of bias was assessed using the Prediction Model Study Risk of Bias Assessment Tool. Meta-regression was performed to summarize the performance of the models and to compare the accuracy of the models with that of physicians. Results The search resulted in 54 studies being included in the meta-analysis. Nine generative AI models were evaluated across 17 medical specialties. The quality assessment indicated a high risk of bias in the majority of studies, primarily due to small sample sizes. The overall accuracy for generative AI models across 54 studies was 56.9% (95% confidence interval [CI]: 51.0–62.7%). The meta-analysis demonstrated that, on average, physicians exceeded the accuracy of the models (difference in accuracy: 14.4% [95% CI: 4.9–23.8%], p-value =0.004). However, both Prometheus (Bing) and GPT-4 showed slightly better performance compared to non-experts (-2.3% [95% CI: -27.0–22.4%], p-value = 0.848 and -0.32% [95% CI: -14.4–13.7%], p-value = 0.962), but slightly underperformed when compared to experts (10.9% [95% CI: -13.1–35.0%], p-value = 0.356 and 12.9% [95% CI: 0.15–25.7%], p-value = 0.048). The sub-analysis revealed significantly improved accuracy in the fields of Gynecology, Pediatrics, Orthopedic surgery, Plastic surgery, and Otolaryngology, while showing reduced accuracy for Neurology, Psychiatry, Rheumatology, and Endocrinology compared to that of General Medicine. No significant heterogeneity was observed based on the risk of bias. Conclusions Generative AI exhibits promising diagnostic capabilities, with accuracy varying significantly by model and medical specialty. Although they have not reached the reliability of expert physicians, the findings suggest that generative AI models have the potential to enhance healthcare delivery and medical education, provided they are integrated with caution and their limitations are well-understood. Key Points Question:What is the diagnostic accuracy of generative AI models and how does this accuracy compare to that of physicians? Findings:This meta-analysis found that generative AI models have a pooled accuracy of 56.9% (95% confidence interval: 51.0–62.7%). The accuracy of expert physicians exceeds that of AI in all specialties, however, some generative AI models are comparable to non-expert physicians. Meaning:The diagnostic performance of generative AI models suggests that they do not match the level of experienced physicians but that they may have potential applications in healthcare delivery and medical education.

  Cold Spring Harbor Laboratory, 22 Jan. 2024, medRxiv


• 周術期のアミノ酸投与による心臓手術関連腎障害抑制効果の検討:単施設単盲検無作為化比較試験

  加澤昌広, 加葉田大志朗, 吉田寿子, 南公人, 前田琢磨, 吉谷健司, 松田均, 新谷歩

  2024, 日本集中治療医学会学術集会(Web), 51st


• Disease Duration Differentially Affects the Clinical Efficacy of Biologics and JAK Inhibitors in Rheumatoid Arthritis: The ANSWER Cohort Study

  Nakayama Y., Kabata D., Yamamoto W., Makino H., Nagai K., Yoshida N., Son Y., Katayama M., Yamada H., Nishimura K., Hara R., Watanabe R., Etani Y., Ebina K., Onizawa H., Fujii T., Onishi A., Murakami K., Murata K., Tanaka M., Matsuda S., Morinobu A., Shintani A., Hashimoto M.

  2024, Arthritis Rheumatol., 76

  [Refereed]


• 慢性腰痛症に対する各種薬物療法の有効性の比較 全国多施設共同研究

  井上 玄, 海渡 貴司, 松山 幸弘, 山下 敏彦, 川上 守, 高橋 和久, 吉田 宗人, 今釜 史郎, 大鳥 精司, 田口 敏彦, 波呂 浩孝, 種市 洋, 山崎 正志, 西田 康太郎, 山田 宏, 加葉田 大志朗, 新谷 歩, 岩崎 幹季, 伊東 学, 宮腰 尚久, 村上 英樹, 米延 策雄, 田倉 智之, 持田 譲治, 日本脊椎脊髄病学会プロジェクト委員会

  (一社)日本脊椎脊髄病学会, Mar. 2021, Journal of Spine Research, 12(3) (3), 336 - 336, Japanese


• Comparison of the effectiveness of four major drugs for chronic low back pain: A nationwide multicenter study

  井上玄, 海渡貴司, 松山幸弘, 山下敏彦, 川上守, 高橋和久, 吉田宗人, 今釜史郎, 大鳥精司, 田口敏彦, 波呂浩孝, 種市洋, 山崎正志, 西田康太郎, 山田宏, 加葉田大志朗, 新谷歩, 岩崎幹季, 伊東学, 宮腰尚久, 村上英樹, 米延策雄, 田倉智之, 持田譲治

  2021, Journal of Spine Research (Web), 12(3) (3)


• Statistical analysis method for Clinical study

  加葉田大志朗

  (一社)京都府理学療法士会, 2021, 理学療法京都, (50) (50), 22 - 28, Japanese


• 慢性腰痛症に対する薬物療法の合併症評価 肝腎機能障害を中心に 日本脊椎脊髄病学会主導多施設前向き追跡調査

  由留部 崇, 西田 康太郎, 加葉田 大志朗, 海渡 貴司, 持田 讓治, 松山 幸弘, 山下 敏彦, 川上 守, 田口 敏彦, 山崎 正志, 山田 宏, 波呂 浩孝, 村上 英樹, 宮腰 尚久, 今釜 史郎, 井上 玄, 新谷 歩

  (一社)日本脊椎脊髄病学会, Mar. 2020, Journal of Spine Research, 11(3) (3), 73 - 73, Japanese


• 慢性腰痛症の薬物治療効果に影響する背景因子 多施設前向き研究

  今釜 史郎, 村上 英樹, 持田 讓治, 松山 幸弘, 山下 敏彦, 川上 守, 田口 敏彦, 波呂 浩孝, 山崎 正志, 海渡 貴司, 井上 玄, 西田 康太郎, 宮腰 尚久, 山田 宏, 加葉田 大志朗, 新谷 歩

  (一社)日本脊椎脊髄病学会, Mar. 2020, Journal of Spine Research, 11(3) (3), 73 - 73, Japanese


• Impact of background factors for outcome in pharmacological therapy for chronic low back pain-the nationwide multicenter prospective study

  今釜史郎, 今釜史郎, 村上英樹, 持田讓治, 松山幸弘, 山下敏彦, 川上守, 田口敏彦, 波呂浩孝, 山崎正志, 海渡貴司, 井上玄, 西田康太郎, 宮腰尚久, 山田宏, 加葉田大志朗, 新谷歩

  2020, Journal of Spine Research (Web), 11(3) (3)


• Adverse liver and kidney effects of analgesics for chronic low back pain: a nationwide multicenter prospective cohort study by the Japanese Society for Spine Surgery and Related Research

  由留部崇, 由留部崇, 西田康太郎, 西田康太郎, 加葉田大志朗, 海渡貴司, 持田讓治, 松山幸弘, 山下敏彦, 川上守, 田口敏彦, 山崎正志, 山田宏, 波呂浩孝, 村上英樹, 宮腰尚久, 今釜史郎, 井上玄, 新谷歩

  2020, Journal of Spine Research (Web), 11(3) (3)


• 無作為化

  新谷歩, 加葉田大志朗

  Mar. 2019, AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト

  [Refereed]


• 比例ハザード回帰モデル

  新谷歩, 加葉田大志朗

  Mar. 2019, AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト

  [Refereed]


• 生存時間解析

  新谷歩, 加葉田大志朗

  Mar. 2019, AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト

  [Refereed]


• ロジスティック回帰モデル

  新谷歩, 加葉田大志朗

  Mar. 2019, AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト

  [Refereed]


• 線形回帰モデル

  新谷歩, 加葉田大志朗

  Mar. 2019, AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト

  [Refereed]


• 多変量解析

  新谷歩, 加葉田大志朗

  Mar. 2019, AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト

  [Refereed]


• 統計学的検討について

  加葉田 大志朗, 新谷 歩

  へるす出版, Mar. 2019, 救急医学 = The Japanese journal of acute medicine, 43(3) (3), 269 - 276, Japanese


• Statistical analysis of observational study

  加葉田大志朗, 新谷歩

  In any observational study where an exposure of interest, such as pharmaceutical treatment, is not randomly assigned to subjects, a bias is often introduced in estimating the true effect of treatment. This is because patients who receive treatment usually have more severe medical conditions than those without treatment. Failure to control such inherent bias in patient characteristics when assessing for the true effect of treatment across comparison groups, may lead to confounding. The presence of confounding makes it difficult to evaluate the true treatment effect. In this paper, we will introduce statistical strategies which aim to remove the effects of confounding in observational studies.

  Japan Society of Pain Clinicians, 2019, 日本ペインクリニック学会誌, 26(1) (1), 1 - 6, Japanese


• Introduction to Cost-Effectiveness Research

  加葉田大志朗, 新谷歩

  医学書院, 2019, 臨床整形外科, 54(8) (8), 767 - 770, Japanese


• 平成30年度大阪府下慢性透析患者の実態調査

  長沼俊秀, 武本佳昭, 内田潤次, 仲谷達也, 加葉田大志朗, 新谷歩

  大阪透析研究会, 2019, 大阪透析研究会会誌, 37(2) (2), 149 - 165, Japanese


• Statistical analysis of observational data with multivariable regression model and propensity score methods

  加葉田大志朗, 新谷歩

  日本糖尿病・妊娠学会, 2018, 糖尿病と妊娠 : 日本糖尿病・妊娠学会誌 = Diabetes & pregnancy : the journal of the Japanese Society of Diabetes and Pregnancy, 18(2) (2), S - 59, Japanese


• Check-list for statistical analysis in publishing medical science papers

  加葉田大志朗, 新谷歩

  克誠堂出版, 2018, 麻酔 = The Japanese journal of anesthesiology : 日本麻酔科学会準機関誌, 67(増刊) (増刊), S226 - S233, Japanese


• 検定の選び方：検定は結論を変え得る！ 不適切な検定を故意に選ぶのは不正行為

  新谷歩, 加葉田大志朗

  Mar. 2017, AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト

  [Refereed]


• 症例数の設計：信頼できるエビデンスを得るために症例数は計画時に必ず決めておく

  新谷歩, 加葉田大志朗

  Mar. 2017, AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト

  [Refereed]


• 多重性の問題：研究計画の重要性

  新谷歩, 加葉田大志朗

  Mar. 2017, AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト


• 検定とP値：統計的エビデンスとは

  新谷歩, 加葉田大志朗

  Mar. 2017, AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト

  [Refereed]


• 記述統計量とグラフの描き方

  新谷歩, 加葉田大志朗

  Mar. 2017, AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト

  [Refereed]


• 正しいデータの記述の仕方

  新谷歩, 加葉田大志朗

  Mar. 2017, AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト

  [Refereed]


• 国際誌が求める統計：チェックリストの活用

  新谷歩, 加葉田大志朗

  Mar. 2017, AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト

  [Refereed]


• 希少難治性角膜疾患の疫学調査 疫学調査のためのデータベース構築に向けた取り組みに関する研究

  新谷歩, 山本景一, 山田知美, 山本紘司, 太田恵子, 関季子, 原正彦, 横濱則也, 高橋佳苗, 橋本治子, 加葉田大志朗, YI Zhou

  2017, 希少難治性角膜疾患の疫学調査 平成28年度 総括・分担研究報告書(Web)


• 希少難治性角膜疾患の疫学調査に関する研究 疫学調査のためのデータベース構築に向けた取り組み

  新谷歩, 山本景一, 山田知美, 山本紘司, 太田恵子, 関季子, 原正彦, 高橋佳苗, 橋本治子, 加葉田大志朗, YI Zhou

  2016, 希少難治性角膜疾患の疫学調査に関する研究 平成27年度 総括・分担研究報告書

• AI技術を活用！特定保健指導の効果を対象者ごとに可視化

  加葉田大志朗

  株式会社法研 へるすあっぷ21 2026年4月号（NO.498）, Apr. 2026


• 医学研究のためのRによる統計解析入門

  加葉田大志朗

  オーム社, Sep. 2023, Japanese, ISBN: 9784274230905

• Foundations and Advanced Topics of Statistical Causal Inference Using Machine Learning

  加葉田 大志朗

  2026年度 統計関連連合大会 企画セッション講演：統計数理研究所医療健康データ科学研究センター「医療健康データ科学のフロンティア」, Sep. 2026

  [Invited]


• Imputation of individual survival times in statistical causal inference and causal discovery

  Daijiro Kabata

  統計数理研究所 共同利用セミナー「生存時間を評価項目とする統計的因果推論における機械学習の活用」, Jul. 2026

  [Invited]


• 臨床研究における統計解析

  加葉田大志朗

  日本環境感染学会教育委員会主催 医療疫学トレーニングコース上級編, Feb. 2026

  [Invited]


• 外部対照を用いた非劣性試験の感度分析

  加葉田大志朗, 今井匠

  日本臨床試験学会 第17回学術集会総会, Feb. 2026


• 臨床研究におけるデータ分析のノウハウ

  加葉田大志朗

  Physio Study Kyoto Private Seminar, Feb. 2026


• 機械学習を応用した統計的因果推論アプローチとその周辺

  加葉田大志朗

  久留米大学バイオ統計センター 公開セミナー, Jan. 2026

  [Invited]


• 非劣性の評価を目的とした観察研究における感度分析

  加葉田大志朗, 今井匠

  第9回かごしまデータ科学シンポジウム in FUKUOKA, Dec. 2025


• 大手自動車メーカーにおける強制的な稼働休止による従業員のBMIの変化の検討

  丸居誉, 垣内紀亮, 池田直子, 川合睦子, 貝森亜紀, 佐伯紀子, 梶本勝文, 田中里穂, 銭谷亜弓, 松宮さおり, 加葉田大志朗, 是恒之宏

  第35回 日本産業衛生学会 全国協議会, Nov. 2025


• 汎用的手術時間予測モデルの構築と手術室割り当て最適化への応用

  加葉田 大志朗, 伊藤 真理, Bai Xinyun, 陳 思楠, 古賀 聡人, 柚木 一馬

  ヘルスデータサイエンス学会 第4回学術集会, Nov. 2025


• Evaluation of the Effect of Tetracycline and Fluoroquinolone Combination Therapy for Japanese Spotted Fever: A Comprehensive Analysis of Case Reports and Case Series．

  Kazuhiro Itoh, Daijiro Kabata, Hiroko Shigemi, Tomoya Hirota, Ippei Sakamaki, Hiroshi Tsutani, Yasuhiko Mitsuke, Hiromichi Iwasaki

  The 20th Asia Pacific Congress of Clinical Microbiology and Infection, Nov. 2025


• AI技術を用いた個人レベルの特定保健指導効果の推定アプリの構築

  加葉田大志朗, 坂庭嶺人

  第84回 日本公衆衛生学会総会, Oct. 2025


• A Mixed-Integer Programming Framework for Prediction-Based Operating Room Scheduling.

  Xinyun Bai, Mari Ito, Daijiro Kabata, Sinan Chen, Masaaki Suzuki, Tokito Koga, Kazuma Yunoki

  Operations Research Society of Japan 2025 Fall Research Presentation & Symposium, Sep. 2025


• X連鎖性低リン血症性くる病/骨軟化症患者における副甲状腺機能亢進症の合併率および腎機能障害との関連

  伊東伸朗, 道上敏美, 難波範行, 窪田拓生, 新谷歩, 加葉田大志, 石井遥, 福本誠二, 大薗恵一

  第98回日本内分泌学会学術総会, Jun. 2025


• 血液透析患者におけるT50推算式の開発

  上殿英記, 庄司哲雄, 加葉田大志朗, 仲谷慎也, 永田友貴, 藤井比佐子, 森岡与明, 森克仁, 繪本正憲

  第70回 日本透析医学会学術集会・総会, May 2025


• X連鎖性低リン血症くる病小児患者における血圧と関連因子 ： SUNFLOWER縦断的観察研究のスナップショットデータのサブグループ解析

  藤原香緒, 加葉田大志, 河合稜太, Hee Gyung Ka, 難波範行, 東, 伸朗, 谷, 福本誠二, 大薗恵一, 道上敏美

  第60回 日本小児腎臓病学会学術集会, May 2025


• エビデンス構築に必要な統計学の知識

  加葉田大志朗

  第29回 日本徒手理学療法学術大会 教育講演, Feb. 2025

  [Invited]


• 臨床研究に必要な統計学の知識

  加葉田大志朗

  第29回 日本徒手理学療法学術大会 プレセミナー, Feb. 2025

  [Invited]


• Individualized Treatment Effects Using a Flexible Bayesian Modeling Approach

  Daijiro Kabata, Nicholas C. Henderson, Ravi Varadhan

  ICHPS 2025, Jan. 2025

  [Invited]


• 観察研究で実施する効果検証

  加葉田大志朗

  日本運動器理学療法学会 2024年度 第3回サテライトカンファレンス, Dec. 2024

  [Invited]


• Analysis of baseline data from the SUNFLOWER longitudinal, observational cohort study: relationship between various complications and QOL

  Noriyuki Namba, Nobuaki Ito, Toshimi Michigami, Hee Gyung Kang, Takuo Kubota, Osamu Miyazaki, Ayumi Shintani, Daijiro Kabata, Yayoi Nishida, Seiji Fukumoto, Keiichi Ozono

  The 62nd Annual ESPE Meeting 2024, Nov. 2024


• Disease Duration Differentially Affects the Clinical Efficacy of Biologics and JAK Inhibitors in Rheumatoid Arthritis: The ANSWER Cohort Study

  Yoichi Nakayama, Daijiro Kabata, Wataru Yamamoto, Hidehiko Makino, Koji Nagai, Naofumi Yoshida, Yonsu Son, Masaki Katayama, Hirotaka Yamada, Keisuke Nishimura, Ryota Hara, Ryu Watanabe, Yuki Etani, Kosuke Ebina, Hideo Onizawa, Takayuki Fujii, Akira Onishi, Kosaku Murakami, Koichi Murata, Masao Tanaka, Shuichi Matsuda, Akio Morinobu, Ayumi Shintani, Motomu Hashimoto

  ACR Convergence 2024, Nov. 2024


• 臨床研究デザイン学習会

  加葉田大志朗

  日本リハビリテーション医学会 臨床研究デザイン学習会, Aug. 2024

  [Invited]


• 医療統計学～間違っているのは自分か分析か？～

  加葉田大志朗

  神戸学院大学大学院 総合リハ日テーション学研究科 特別公開講座, Sep. 2023

  [Invited]


• 臨床研究デザイン学習会

  加葉田大志朗

  日本リハビリテーション医学会 臨床研究デザイン学習会, Aug. 2023

  [Invited]


• 外傷性凝固障害におけるアンチトロンビンの動態とDIC発症,予後との関係

  和田 剛志, 白石 淳, 丸藤 哲, 加葉田 大志朗, 山川 一馬, 藤島 清太郎, 齋藤 大蔵, 久志本 成樹, 小倉 裕司, 真弓 俊彦, 大友 康裕

  第45回 日本血栓止血学会, Jun. 2023


• 胸腺からのT細胞産生減少は慢性腎臓病の進行を予測する

  飯尾健一郎, 加葉田大志朗, 飯尾麗, 芝元心一, 渡邊悠希, 森田将史, 今井洋輔, 畑中雅喜, 大森弘基, 猪阪善隆

  第23回 日本抗加齢医学会総会, Jun. 2023


• L-ドパ含有製剤で治療開始した早期パーキンソン病患者における薬剤処方パターンの検証

  栗崎玲一, 加葉田大志朗, 伊田寛之, 新居賢樹, 太田美穂子, 新谷歩, 古澤嘉彦

  第64回 日本神経学会学術大会, May 2023


• 医療疫学トレーニングコース上級編

  加葉田大志朗

  2022年度 日本環境感染学会教育委員会主催 医療疫学トレーニングコース, Nov. 2022

  [Invited]


• The background of XLH patients with burosumab treatment and its short-term effectiveness and safety of: Interim analysis of the SUNFLOWER study.

  Toshimi Michigami, Hee Gyung Kang, Noriyuki Namba, Nobuaki Ito, Takuo Kubota, Ayumi Shintani, Daijiro Kabata, Masanori Kanematsu, Yayoi Nishida, Seiji Fukumoto, Keiichi Ozono

  APPES 2022, Oct. 2022


• 医療統計学

  加葉田大志朗

  日本成人矯正歯科学会認定医研修プログラム, Jul. 2022

  [Invited]


• 胸腺機能低下は慢性腎臓病の進行を予測する

  飯尾健一郎, 加葉田大志朗, 飯尾麗, 芝元心一, 渡邊悠希, 森田将史, 今井洋輔, 畑中雅喜, 猪阪善隆

  第65回 日本腎臓学会誌, Jun. 2022


• AIを用いた臨床研究は一般的な臨床研究とは別物なのか?

  加葉田大志朗

  第2回 日本腎・血液浄化AI学会学術集会・総会, Jun. 2022

  [Invited]


• 同種造血幹細胞移植における機械学習を用いた患者個別の最適移植法推奨戦略

  岡村浩史, 岡村浩史, 中前博久, 中前美佳, 中前美佳, 加葉田大志朗, 吉田寿子, 新谷歩, 内田直之, 土岐典子, 福田隆浩, 小澤幸泰, 田中正嗣, 池亀和博, 衛藤徹也, 澤正史, 木村貴文, 諫田淳也, 熱田由子, 日野雅之, 日野雅之

  第44回 日本造血・免疫細胞療法学会総会, May 2022


• 腎機能とコレステロール合成・吸収との関連:CACHE研究CKD解析

  庄司哲雄, 庄司哲雄, 秋山雄介, 藤井比佐子, 斯波真理子, 石橋豊, 石田達郎, 石垣泰, 加葉田大志朗, 木原康樹, 小谷和彦, 栗栖智, 増田大作, 的場哲哉, 松木恒太, 松村剛, 森健太, 中神朋子, 中里正光, 谷内颯樹, 上野浩晶, 山下静也, 吉田博, 吉田寿子, 庄司哲雄

  第34回 腎と脂質研究会, Mar. 2022


• 統計ブートキャンプ＠オンライン

  加葉田大志朗, 新谷歩, 市川家國

  AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト, Feb. 2022

  [Invited]


• 医療疫学トレーニングコース上級編

  加葉田大志朗

  2021年度 日本環境感染学会教育委員会主催 医療疫学トレーニングコース, Oct. 2021

  [Invited]


• 加齢に伴う肝切除術後感染リスクと感染病態の解明およびその対策

  木下 正彦, 新川 寛二, 加葉田 大志朗, 竹村 茂一, 田中 肖吾, 天野 良亮, 木村 健二郎, 大平 豪, 西尾 康平, 久保 正二

  第76回 日本消化器外科学会総会, Jul. 2021


• 統計ブートキャンプ@オンライン

  加葉田大志朗, 新谷歩, 市川家國

  AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト, Feb. 2021

  [Invited]


• TMAとDICの併存~そのkey mediatorはトロンボモジュリンである~

  和田剛志, 丸藤哲, 丸藤哲, 山川一馬, 加葉田大志朗, 新谷歩, 小倉裕司, 梅村譲, 白石淳, 齋藤大蔵, 藤島清太郎, 真弓俊彦, 久志本成樹, 阿部智一, 阿部智一, 椎野泰和, 中田孝明, 樽井武彦, 一二三亨, 岡本好司, 小谷譲治, 坂本雄一郎, 佐々木淳一, 白石振一郎, 田熊清継, 鶴田良介, 萩原章嘉, 増野智彦, 武山直志, 山下典雄, 池田弘人, 上山昌史, 藤見聡, 大友康裕, 大友康裕

  第48回 日本集中治療医学会学術集会, Feb. 2021


• JAAM基準をベースにした抗凝固療法が有効性を示す患者集団の検討

  和田剛志, 山川一馬, 丸藤哲, 丸藤哲, 加葉田大志朗, 新谷歩, 小倉裕司, 梅村譲, 白石淳, 齋藤大蔵, 藤島清太郎, 真弓俊彦, 久志本成樹, 阿部智一, 阿部智一, 椎野泰和, 中田孝明, 樽井武彦, 一二三亨, 岡本好司, 小谷譲治, 坂本雄一郎, 佐々木淳一, 白石振一郎, 田熊清継, 鶴田良介, 萩原章嘉, 増野智彦, 武山直志, 山下典雄, 池田弘人, 上山昌史, 藤見聡, 大友康裕

  第48回 日本集中治療医学会学術集会, Feb. 2021


• 臨床研究におけるAIの役割

  加葉田大志朗

  Thrombocardiology Expert Meeting, Dec. 2020

  [Invited]


• 生体腎移植ドナー候補を対象とした新たなeGFR算出式の作成

  谷口歩, 今村亮一, 川村正隆, 中澤成晃, 加藤大悟, 阿部豊文, 山中和明, 岸川英史, 加葉田大志朗, 新谷歩, 野々村祝夫

  第108回 日本泌尿器科学会総会, Dec. 2020


• 統計コンサルで遭遇する難題～臨床感が解析に反映されるまで～

  加葉田大志朗

  中外製薬 医療統計勉強会～リウマチ関連を中心に～, Nov. 2020

  [Invited]


• 医療統計学

  加葉田大志朗

  日本成人矯正歯科学会 認定医研修プログラム, Sep. 2020

  [Invited]


• 統計方法論~怖くない統計学と臨床研究~

  加葉田大志朗

  京都府理学療法士会 第１回・第２回研修会, Sep. 2020

  [Invited]


• 臨床研究におけるAIの役割

  加葉田大志朗

  第42回 日本血栓止血学会, Jun. 2020

  [Invited]


• Variable selection in double/debiased machine learning for causal inference: Anoutcome-adaptive Lasso approach

  加葉田 大志朗, 新谷 元嗣

  2019年 関西計量経済学研究会, Jan. 2020


• 実践！医療統計セミナー５

  加葉田大志朗

  NHO大阪南医療センター 特別講演会, Jan. 2020

  [Invited]


• 医療統計教室

  加葉田大志朗

  データ利活用フェスティバル, Jan. 2020

  [Invited]


• 実践！医療統計セミナー４

  加葉田大志朗

  NHO大阪南医療センター 特別講演会, Dec. 2019

  [Invited]


• 統計ブートキャンプ@大阪

  加葉田大志朗, 新谷歩, 市川家國

  AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト, Dec. 2019

  [Invited]


• 統計ブートキャンプ@東京

  加葉田大志朗, 新谷歩, 市川家國

  AMED研究公正⾼度化モデル開発⽀援事業研究者皆学習プロジェクト, Dec. 2019

  [Invited]


• 実践で身につける医療統計

  加葉田大志朗

  Physio Study Kyoto 2019年第２１回研修会, Nov. 2019

  [Invited]


• 実践！医療統計セミナー３

  加葉田大志朗

  NHO大阪南医療センター 特別講演会, Nov. 2019

  [Invited]


• 腎移植患者のフレイルの関連因子についての検討

  香束昌宏, 内田潤次, 岩井友明, 長沼俊秀, 前田景子, 加葉田大志朗, 新谷歩, 仲谷達也

  第6回 日本サルコペニア・フレイル学会, Nov. 2019


• 実践！医療統計セミナー２

  加葉田大志朗

  NHO大阪南医療センター 特別講演会, Sep. 2019

  [Invited]


• 医療統計学勉強会

  加葉田大志朗

  近畿病歴管理セミナー, Aug. 2019

  [Invited]


• 実践！医療統計セミナー１

  加葉田大志朗

  NHO大阪南医療センター 特別講演会, Jun. 2019

  [Invited]


• Clinical importance of trunk muscle mass for low back pain, spinal balance, and quality of life-a multicenter cross-sectional study.

  Hori Y., Hoshino M., Inage K., Miyagi M., Takahashi S., Ohyama S., Suzuki A., Tsujio T., Terai H., Dohzono S., Sasaoka R., Toyoda H., Kato M., Matsumura A., Namikawa T., Seki M., Yamada K., Habibi H., Salimi H., Yamashita M., Yamauchi T., Furuya T., Orita S., Maki S., Shiga Y., Inoue M., Inoue G., Fujimaki H., Murata K., Kawakubo A., Kabata D., Shintani A., Ohtori S., Takaso M., Nakamura H.

  ISSLS 2019, May 2019


• CKD患者におけるPTHと胸腺萎縮の関係

  飯尾健一郎, 加葉田大志朗, 飯尾麗, 星田義彦, 佐伯行彦, 新谷歩, 濱野高行, 猪阪義隆, 安東豊

  第3回 日本CKDーMBD研究会学術集会・総会, Mar. 2019


• 無作為化比較試験における時系列データを用いた解析の有用性の検討

  武田裕里子, 加葉田大志朗, 新谷歩

  日本薬学会 第139年会, Mar. 2019


• 実践で身につける統計学

  加葉田大志朗

  Physio Study Kyoto 2018年第１６回研修会, Feb. 2019

  [Invited]


• 実践！医療統計セミナー４

  加葉田大志朗

  NHO大阪南医療センター 特別講演会, Feb. 2019

  [Invited]


• 統計ブートキャンプ@東京

  加葉田大志朗, 新谷歩, 市川家國

  AMED研究公正⾼度化モデル開発⽀援事業医系国際誌プロジェクト, Feb. 2019

  [Invited]


• 五角形角膜内皮細胞は年齢によって大きくなりにくい

  部坂優子, 辻川元一, 辻川元一, 加葉田大志朗, 新谷歩, 西田幸二

  第43回 日本角膜学会総会・日本角膜移植学会, Feb. 2019


• コンタクトレンズドライアイ問診票J-CLDEQ-8の開発とその妥当性の検討

  高静花, CHALMERS Robin, 加葉田大志朗, 新谷歩, 西田幸二

  第43回 日本角膜学会総会;日本角膜移植学会, Feb. 2019


• 生体腎移植ドナーを対象とした新たなeGFR算出式の作成

  中澤成晃, 川村正隆, 加藤大悟, 阿部豊文, 谷口歩, 山中和明, 吉田栄宏, 岸川英史, 西村憲二, 加葉田大志朗, 今村亮一, 新谷歩, 野々村祝夫

  第52回 日本臨床腎移植学会, Feb. 2019


• 統計ブートキャンプ

  加葉田大志朗

  ひろしま麻酔科エキスパートセミナー, Jan. 2019

  [Invited]


• 実践！医療統計セミナー３

  加葉田大志朗

  NHO大阪南医療センター 特別講演会, Dec. 2018

  [Invited]


• 実践！医療統計セミナー２

  加葉田大志朗

  NHO大阪南医療センター 特別講演会, Sep. 2018

  [Invited]


• 統計ブートキャンプ@大阪

  加葉田大志朗, 新谷歩, 市川家國

  AMED研究公正⾼度化モデル開発⽀援事業医系国際誌プロジェクト, Aug. 2018

  [Invited]


• 実践！医療統計セミナー１

  加葉田大志朗

  NHO大阪南医療センター 特別講演会, Jun. 2018

  [Invited]


• 実践！医療統計セミナー５

  加葉田大志朗

  NHO大阪南医療センター 特別講演会, Apr. 2018

  [Invited]


• 医療統計学

  加葉田大志朗

  日本成人矯正歯科学会 認定医研修, Apr. 2018

  [Invited]


• 関節リウマチ患者において喫煙はTNF阻害剤の効果を減弱させる:TNFαと喫煙(AhR)シグナルのクロストーク

  葛谷憲太郎, 新居卓朗, 加葉田大志朗, 大島至郎, 松下正人, 辻聡一郎, 竹花泰雄, 松井利浩, 當間重人, 佐伯行彦

  第115回 日本内科学会総会・講演会, Apr. 2018


• 実践！医療統計セミナー４

  加葉田大志朗

  NHO大阪南医療センター 特別講演会, Feb. 2018

  [Invited]


• 腎移植の血管石灰化の問題

  長沼俊秀, 武本佳昭, 香束昌宏, 内田潤次, 仲谷達也, 加葉田大志朗, 新谷歩

  第51回 日本臨床腎移植学会, Feb. 2018


• 実践で身につける医療統計

  加葉田大志朗

  Physio Study Kyoto 2017年第１０回研修会, Jan. 2018

  [Invited]


• 実践！医療統計セミナー３

  加葉田大志朗

  NHO大阪南医療センター 特別講演会, Dec. 2017

  [Invited]


• 統計ブートキャンプ@東京

  加葉田大志朗, 新谷歩, 市川家國

  AMED研究公正⾼度化モデル開発⽀援事業医系国際誌プロジェクト, Dec. 2017

  [Invited]


• 統計ブートキャンプ@大阪

  加葉田大志朗, 新谷歩, 市川家國

  AMED研究公正⾼度化モデル開発⽀援事業医系国際誌プロジェクト, Oct. 2017

  [Invited]


• 医療従事者のための統計学

  加葉田大志朗

  英ウィメンズクリニック教育講演会, Oct. 2017

  [Invited]


• 統計学

  加葉田大志朗

  Physio Study Kyoto 2017年第８回研修会, Sep. 2017


• 実践！医療統計セミナー２

  加葉田大志朗

  NHO大阪南医療センター 特別講演会, Sep. 2017

  [Invited]


• 実践！医療統計セミナー１

  加葉田大志朗

  NHO大阪南医療センター 特別講演会, Jul. 2017

  [Invited]


• コンセプト×実践で学ぶ統計学～統計学を臨床で活用しよう～

  加葉田大志朗

  生殖補助医療技術者のためのリカレントセミナー, Jul. 2017

  [Invited]


• 医学研究における統計学

  加葉田大志朗

  島田病院教育講演会, Mar. 2017

  [Invited]


• 交互作用を含む観察データにおける傾向スコア解析手法による結果の差異

  加葉田大志朗, 山本紘司, 新谷歩

  科学研究費・基盤研究（A)「大規模複雑データの理論と方法論の総合的研究」シンポジウム「統計科学の現代的課題」, Jan. 2017


• 統計学

  加葉田大志朗

  Physio Study Kyoto 2016年第４回研修会, Dec. 2016

  [Invited]


• 研究デザインについて

  加葉田大志朗

  R3-united 12月研修会, Dec. 2016

  [Invited]


• 統計学

  加葉田大志朗

  Physio Study Kyoto 2016年第１回研修会, May 2016

  [Invited]

• 日本臨床試験学会

  2025 - Present


• 日本行動計量学会

  2025 - Present


• ヘルスデータサイエンス学会

  2025 - Present


• Japan Epidemiological Association

  2025 - Present


• Japanese Society of Public Health

  2025 - Present


• International Biometric Society

  2018 - Present


• Biometric Society of Japan

  2018 - Present

• 統計的因果探索の生存時間分析への橋渡し

  加葉田大志朗

  日本学術振興会, 科学研究費助成事業, 基盤研究(C)（一般）, Apr. 2026 - Mar. 2029, Principal investigator


• Application of Machine Learning to Causal Inference in Survival Analysis

  The Institute of Statistical Mathematics, 公募型共同利用, 重点型研究 データ解析の妥当性と質を高める生存時間分析法の開発と利用, Apr. 2026 - Mar. 2027, Principal investigator


• 統計的因果探索に基づく再雇用の規定因子の探索

  神戸大学, 学内・学外DX推進共同プロジェクト, 2026 - 2027, Principal investigator


• 公衆衛生介入における効果の異質性を目指した手法開発とデータベース研究への応用

  神戸大学, 学内・学外DX推進共同プロジェクト, 2026 - 2027, Principal investigator


• ベイズ機械学習による因果探索の生存時間分析への応用

  加葉田大志朗

  上原記念生命科学財団, 研究奨励金, 2026 - 2027, Principal investigator


• 機械学習選択の誤りに頑健な治療効果推定量の提案とリアルワールドデータへの応用

  加葉田 大志朗

  日本学術振興会, 科学研究費助成事業, 若手研究, 大阪公立大学, Apr. 2023 - Mar. 2026, Principal investigator


• グローバルな社会課題解析エンジン・プラットフォームの提供

  公益財団法人ひろしまベンチャー育成基金, 第32回ひろしまベンチャー助成金, 2025 - 2026, Principal investigator


• ストレスチェックを活用した女性特有の健康課題の探索

  経産省, フェムテック等サポートサービス実証事業費補助金, 2025 - 2026, Coinvestigator


• 医療データベースから最適な治療ルールを特定する新しい機械学習推定量の提案

  加葉田大志朗

  日本学術振興会, 海外特別研究員（内定後辞退）, Johns Hopkins University, 2024 - 2026


• SNS等を用いたイベント、施設の来場者のデータ分析

  神戸市経済観光局, So-I地域課題解決コース, 2025 - 2025, Principal investigator


• 機械学習による自動的変数選択をもちいた新しい治療効果推定手法の提案

  加葉田 大志朗

  日本学術振興会, 科学研究費助成事業, 若手研究, 大阪市立大学, Apr. 2020 - Mar. 2023, Principal investigator

  因果推論における局外関数の推定に機械学習手法を応用することで，高次元の研究対象者の特性（共変量）を考慮できるというメリットがある一方，関心のある処置の効果推定に必要な情報の削減，局外関数の過適合によって平均処置効果推定量にバイアスが生じるデメリットがあることが知られている．これらのデメリットを低減させるために，計量経済学分野においてdouble/debiased machine learning（DML）推定量が提案された．このDMLは，従来の機械学習を用いた因果推論推定量に比べて優れた性質をもつと考えられるが，臨床研究に応用する際には課題が残る．処置変数に関する局外関数である傾向スコアモデルを推定する際に，lassoなど従来の機械学習手法を利用した場合，処置にのみ関連の強い因子（操作変数）が選択される可能性がある．従来の機械学習で操作変数の影響を強く考慮した傾向スコアモデルは処置変数を良く説明するが，関心のある平均処置効果推定量の分散やバイアスを増加させる恐れがある．臨床研究では操作変数など先験的に特定することは現実的に困難である．従って操作変数が存在するような状況においても，変数選択により頑健な推定量が利用できることが好ましい． 本年度は，上記の問題を改善すべく，以下の2点を目的として研究を行った． （目的１）結果変数に強く関連する因子を優先的に考慮した傾向スコアを利用しつつ，DML推定量の漸近的性質を損なうことがないoutcome-adaptive DML推定量を提案し，そのパフォーマンスを評価すること． （目的2）上記提案手法の臨床観察研究へ応用すること．


• Statistical Approach for Observational Data Analysis

  加葉田 大志朗

  Osaka Metropolitan University, Osaka Metropolitan University Young Researchers Overseas Challenge Program, 2023 - 2023, Principal investigator


• Causal Inference Approach using Machine Learning

  Daijiro Kabata

  Uehara Memorial Foundation, Research Fellowship I, Osaka Metropolitan University, Department of Medical Statistics, Guraduate School of Medicine, 2023 - 2023, Principal investigator


• 医生命学系学会の学会員研究倫理素養の均てん化に向けた学修機会の提供

  代表機関:信州大学,分担機関:大阪市立大学

  AMED, 研究公正高度化モデル開発支援事業, 大阪市立大学, 2020 - 2022, Coinvestigator


• 医系国際誌が規範とする研究の信頼性にかかる倫理教育プログラム

  代表機関:信州大学,分担機関:大阪市立大学

  AMED, 研究公正高度化モデル開発支援事業, 大阪市立大学, 2017 - 2020, Coinvestigator


• The effect of antithrombotic drugs on cerebral hemorrhage volume in patients with intracerebral hemorrhage: Evaluation by causal inference using machine learning approaches

  Daijiro Kabata

  DAIICHI SANKYO COMPANY, LIMITED., Daiichi-Sankyo donation program, Jun. 2018 - Apr. 2019, Principal investigator


• Development and evaluation of a tool to support learning of statistical analysis in nursing research

  ONISHI Yoshihiro, SHINTANI Ayumi, KABATA Daishirou

  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Institute for Health Outcomes & Process Evaluation Research, Apr. 2014 - Mar. 2017, Coinvestigator not use grants

  We developed a tool to support learning of statistical analysis for clinical nurses. The users can experience the thinking process in statistical analysis, which consists descriptive analysis, univariate analysis, multivariate analysis. We examined the effect of this tool on learning statistical analysis when using in the program for learning clinical research. As results, test score about statistical analysis was not significantly improved by using this tool. However, the proportion of participants who completed the lecture of statistical analysis was increased compared to those without using this tool. Therefore, it was suggested that this tool can enhance the effect on learning of statistical analysis by reducing the feeling of difficulty for learning it.