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AKASAKA Hiroaki
Graduate School of Medicine / Faculty of Medical Sciences
Assistant Professor

Research activity information

■ Paper
  • Ge-doped silica fibre for proton beam dosimetry
    M.F. Hassan, W.N.W.A. Rahman, T. Tominaga, M. Geso, H. Akasaka, D.A. Bradley, N.M. Noor
    Jul. 2019, Radiation Physics and Chemistry, 165(108390) (108390), English
    [Refereed]
    Scientific journal

  • Investigation of the potential of using TiO2 nanoparticles as a contrast agent in computed tomography and magnetic resonance imaging
    Hiroaki Akasaka, Naritoshi Mukumoto, Masao Nakayama, Tianyuan Wang, Ryuichi Yada, Yasuyuki Shimizu, Sachiko Inubushi, Katsusuke Kyotani, Keisuke Okumura, Masanori Miyamoto, Ai Nakaoka, Kenta Morita, Yuya Nishimura, Chiaki Ogino, Ryohei Sasaki
    Jul. 2019, Applied Nanoscience, 1 - 6, English
    [Refereed]
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • Ge-doped Silica Fibre Proton Beam Measurements: Thermoluminescence Dose-Response and Glow Curve Characteristics
    M. F. Hassan, W. N, W. A. Rahman, A. B. A. Kadir, N. M. Isa, T. Tominaga, M. Geso, H. Akasaka, D. A. Bradley, N. M. Noor
    Mar. 2019, International Journal of Nanoelectronics and Materials, 11, English
    [Refereed]
    Scientific journal

  • YOSHIDA Aoi, KITAYAMA Yukiya, KIGUCHI Kentaro, YAMADA Takuya, AKASAKA Hiroaki, SASAKI Ryohei, TAKEUCHI Toshifumi
    American Chemical Society, Feb. 2019, Applied Bio Materials, 2(3) (3), 1177 - 1183, English
    [Refereed]
    Scientific journal

  • Characterisation of delaminated GAFCHROMIC™ EBT3 films in clinical photon, proton and 192Ir brachytherapy source
    N Tagiling, R Ab Rashid, R Abdullah, N Dollah, M Geso, T Tominaga, H Akasaka, K Kie, WN Rahman
    2019, Journal of Physics, 1248(012069) (012069), English
    [Refereed]
    Scientific journal

  • RADIOSENSITIZATION EFFECTS AND ROS GENERATION BY HIGH Z METALLIC NANOPARTICLES ON HUMAN COLON CARCINOMA CELL (HCT116) IRRADIATED UNDER 150 MEV PROTON BEAM
    RaizulnasuhaABDULRASHID, SafriZAINALABIDIN, MUHAMMADAFIQKhairilAnuar, TakahiroTOMINAGA, Akasaka Hiroaki, RyoheiSASAKI, KatahiraKIE, KhairunisakABDULRAZAK, BinhTTPHAM, BrianSHAWKETT, Mary-AnnCARMICHAEL, MoshiGESO, WanNordianaRAHMAN
    Nov. 2018, OPEN NANO, 4(100027) (100027), 1 - 8, English
    [Refereed]
    Scientific journal

  • Ryo Nishikawa, Kenji Yoshida, Yasuhiko Ebina, Mayumi Omoteda, Daisuke Miyawaki, Takeaki Ishihara, Yasuo Ejima, Hiroaki Akasaka, Hitoaki Satoh, Katsusuke Kyotani, Satoru Takahashi, Ryohei Sasaki
    This study aimed to compare dosimetric parameters between non-optimized and optimized treatment planning (NOP and OP, respectively) of magnetic resonance imaging (MRI) -based intracavitary (IC) image-guided adaptive brachytherapy (IGABT) using the central shielding (CS) technique for cervical cancer. Fifty-three patients treated with external beam radiotherapy using CS and MRI-based IGABT with the IC approach alone were evaluated. The total high-risk clinical target volume (HR-CTV) D90 was aimed at >70 Gy equivalent dose in 2 Gy fractions (EQD2). In the small HR-CTV group (≤30 cm3), the mean D90s for NOP/OP were 98.6/80.7 Gy. In the large (30.1-40 cm3) and extensive (>40 cm3) HR-CTV groups, the mean D90s were 81.9/77.5 and 71.1/73.6 Gy, respectively. The mean D2cc values for organs at risks (OARs) in OP were acceptable in all groups, despite the high bladder D2cc in the NOP. The correlation between HR-CTV at first brachytherapy (BT) and NOP D90 was stronger than that between HR-CTV at first BT and OP D90. The targeted HR-CTV D90 and dose constraints of D2cc for OARs were both achieved in 16 NOP/47 OP patients for the bladder, 39/50 for the rectum, and 47/50 for the sigmoid colon (P < 0.001, P = 0.007, and P = 0.34, respectively). For small tumors, the role of optimization was to reduce the D2cc for OARs while maintaining the targeted D90. However, optimization was of limited value for extensive tumors. Methods of optimization in IGABT with CS for cervical cancer should be standardized while considering its effectiveness and limitations.
    May 2018, Journal of radiation research, 59(3) (3), 316 - 326, English, International magazine
    [Refereed]
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • Clinical log data analysis for assessing the accuracy of the CyberKnife fiducial-free lung tumor tracking system
    NakayamaM, NishimuraH, MayaharaH, NakamuraM, UeharaK, TsudouS, HaradaA, Akasaka Hiroaki, Sasaki Ryohei
    Mar. 2018, Pract Radiat Oncol, 8(2) (2), e63 - e70, English
    [Refereed]
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • Tianyuan Wang, Takeaki Ishihara, Atsushi Kono, Naoki Yoshida, Hiroaki Akasaka, Naritoshi Mukumoto, Ryuichi Yada, Yasuo Ejima, Kenji Yoshida, Daisuke Miyawaki, Kenichiro Kakutani, Kotaro Nishida, Noriyuki Negi, Toshiaki Minami, Yuuichi Aoyama, Satoru Takahashi, Ryohei Sasaki
    Aug. 2017, PHYSICS IN MEDICINE AND BIOLOGY, 62(15) (15), 6226 - 6245, English
    [Refereed]
    Scientific journal

  • The thermoluminescence response of Ge-doped flat fibre for proton beam measurements: A preliminary study
    M F Hassan, W N Wan, Abdul Rahman, M S Ahmad Fadzil, T Tominaga, M Geso, H Akasaka, D A Bradley, N Mohd Noor
    2017, Journal of Physics, 851(012034) (012034), English
    [Refereed]
    Scientific journal

  • Sparing of tissue by using micro-slit-beam radiation therapy reduces neurotoxicity compared with broad-beam radiation therapy.
    Mukumoto N, Nakayama M, Akasaka H, Shimizu Y, Osuga S, Miyawaki D, Yoshida K, Ejima Y, Miura Yasushi, Umetani K, Kondoh T, Sasaki R
    Jan. 2017, J Radiat Res., 58(1) (1), 17 - 23, English
    [Refereed]
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • Evaluation of a small animal irradiation system for animal experiments using EBT3 model GAFCHROMIC ™ film
    Yasuyuki Shimizu, Hiroaki Akasaka, Daisuke Miyawaki, Naritoshi Mukumoto, Masao Nakayama, Tianyuan Wang, Saki Osuga, Sachiko Inubushi, Ryuichi Yada, Yasuo Ejima, Kenji Yoshida, Takeaki Ishihara, Ryohei Sasaki
    Jan. 2017, Kobe Journal of Medical Sciences, 63(3) (3), E84 - E91, English
    [Refereed]
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • MGDG extracted from spinach enhances the cytotoxicity of radiation in pancreatic cancer cells
    Akasaka Hiroaki, MizushinaY, YoshidaK, Ejima Yasuo, MukumotoN, WangT, InubushiS, NakayamaM, WakaharaY, Sasaki Ryohei
    Nov. 2016, Radiat Oncol, 11(1) (1), 153, English
    [Refereed]
    Scientific journal
    Link to Kobe Univ. Repository (Kernel)

  • The current status of space modulated radiotherapy
    RyoheiSasaki, TianyuanWang, Akasaka Hiroaki, SachikoInubushi, KenjiYoshida, ShoheiKomatsu, YusukeDemizu, TakumiFukumoto
    Sep. 2016, INTERNAL MEDICINE REVIEW, 2(9) (9), 1 - 15, English
    [Refereed]
    Scientific journal

  • Masao Nakayama, Ryohei Sasaki, Chiaki Ogino, Tsutomu Tanaka, Kenta Morita, Mitsuo Umetsu, Satoshi Ohara, Zhenquan Tan, Yuya Nishimura, Hiroaki Akasaka, Kazuyoshi Sato, Chiya Numako, Seiichi Takami, Akihiko Kondo
    BACKGROUND: Biological applications of nanoparticles are rapidly increasing, which introduces new possibilities to improve the efficacy of radiotherapy. Here, we synthesized titanium peroxide nanoparticles (TiOxNPs) and investigated their efficacy as novel agents that can potently enhance the effects of radiation in the treatment of pancreatic cancer. METHODS: TiOxNPs and polyacrylic acid-modified TiOxNPs (PAA-TiOxNPs) were synthesized from anatase-type titanium dioxide nanoparticles (TiO2NPs). The size and morphology of the PAA-TiOxNPs was evaluated using transmission electron microscopy and dynamic light scattering. The crystalline structures of the TiO2NPs and PAA-TiOxNPs with and without X-ray irradiation were analyzed using X-ray absorption. The ability of TiOxNPs and PAA-TiOxNPs to produce reactive oxygen species in response to X-ray irradiation was evaluated in a cell-free system and confirmed by flow cytometric analysis in vitro. DNA damage after X-ray exposure with or without PAA-TiOxNPs was assessed by immunohistochemical analysis of γ-H2AX foci formation in vitro and in vivo. Cytotoxicity was evaluated by a colony forming assay in vitro. Xenografts were prepared using human pancreatic cancer MIAPaCa-2 cells and used to evaluate the inhibition of tumor growth caused by X-ray exposure, PAA-TiOxNPs, and the combination of the two. RESULTS: The core structures of the PAA-TiOxNPs were found to be of the anatase type. The TiOxNPs and PAA-TiOxNPs showed a distinct ability to produce hydroxyl radicals in response to X-ray irradiation in a dose- and concentration-dependent manner, whereas the TiO2NPs did not. At the highest concentration of TiOxNPs, the amount of hydroxyl radicals increased by >8.5-fold following treatment with 30 Gy of radiation. The absorption of PAA-TiOxNPs enhanced DNA damage and resulted in higher cytotoxicity in response to X-ray irradiation in vitro. The combination of the PAA-TiOxNPs and X-ray irradiation induced significantly stronger tumor growth inhibition compared to treatment with either PAA-TiOxNPs or X-ray alone (p < 0.05). No apparent toxicity or weight loss was observed for 43 days after irradiation. CONCLUSIONS: TiOxNPs are potential agents for enhancing the effects of radiation on pancreatic cancer and act via hydroxyl radical production; owing to this ability, they can be used for pancreatic cancer therapy in the future.
    Jul. 2016, Radiation oncology (London, England), 11(1) (1), 91 - 91, English, International magazine
    [Refereed]
    Scientific journal

  • Preclinical evaluation of bioabsorbable polyglycolic acid spacer for particle therapy
    Akasaka Hiroaki, Sasaki Ryohei, Miyawaki Daisuke, Mukumoto N, Sulaiman NS, Nagata M, Yamada S, Murakami M, Demizu Y, Fukumoto T
    Dec. 2014, Int J Radiat Oncol Biol Phys, 90(5) (5), 1177 - 85, English
    [Refereed]
    Scientific journal

■ Books And Other Publications
  • Radiotherapy / A Comparison of Physical vs. Nonphysical Wedge Modalities in Radiotherapy
    Akasaka Hiroaki, NaritoshiMukumoto, MasaoNakayama, TianyuanWang, RyuichiYada, YasuyukiShimizu, SakiOsuga, YukiWakaharaandRyoheiSasaki
    Others, INTECH, 2017, English
    Scholarly book

  • / Medical Application of Nonwoven Fabrics - Intra-abdominal Spacers for Particle Therapy
    RyoheiSasaki, Akasaka Hiroaki, YusukeDemizu, SachikoInubushi, TianyuanWangandTakumiFukumoto
    Others, INTECH, Mar. 2016, English
    Scholarly book

  • 多職種チームで実践する頭頸部がんの化学放射線療法 / 多職種チームで実践する頭頸部がんの化学放射線療法
    丹生健一, 佐々木良平, 大月直樹, Akasaka Hiroaki
    Others, 日本看護協会出版社, Jun. 2015, Japanese
    General book

■ Lectures, oral presentations, etc.
  • 放射線治療のための金ナノ粒子内包アルブミンインプリントナノゲルの創製
    KITAYAMA YUKIYA, 山田託也, 木口 健太朗, 吉田 碧衣, AKASAKA HIROAKI, NISHIMURA YUYA, 五十嵐 一紀, 松本 有, SASAKI RYOHEI, TAKEUCHI TOSHIFUMI
    日本化学会 第99春季年会 (2019), Mar. 2019, English, 日本化学会, 神戸市, Domestic conference
    Oral presentation

  • Radiation therapy for pancreatic cancer using moluculaly imprintednanogels imcopolating gold nanoparticles
    YOSHIDA Aoi, KIGUCHI Kentaro, KITAYAMA Yukiya, AKASAKA Hiroaki, SASAKI Ryohei, TAKEUCHI Toshifumi
    日本化学会 第99春季年会 (2019), Mar. 2019, English, 日本化学会, 神戸市, Domestic conference
    Poster presentation

  • Gold nanoparticle incorporated polymer nanogels for radiation therapy
    YOSHIDA Aoi, YAMADA Takuya, KIGUCHI Kentaro, AKASAKA Hiroaki, SASAKI Ryohei, KITAYAMA Yukiya, TAKEUCHI Toshifumi
    第66回応用物理学会春季学術講演会, Mar. 2019, English, 応用物理学会, 東京都目黒区, Domestic conference
    Poster presentation

  • 放射線治療のための金ナノ粒子内包分子インプリントポリマーナノゲルの開発
    北山 雄己哉, 山田託也, 木口 健太朗, 吉田 碧衣, AKASAKA HIROAKI, NISHIMURA YUYA, 五十嵐 一紀, 松本 有, SASAKI RYOHEI, TAKEUCHI TOSHIFUMI
    第40回日本バイオマテリアル学会大会, Nov. 2018, Japanese, 日本バイオマテリアル学会, 神戸市, Domestic conference
    Oral presentation

  • 放射線治療のための金ナノ粒子内包分子インプリントポリマーナノゲルの開発
    北山 雄己哉, 山田 託也, 木口 健太朗, 吉田 碧衣, AKASAKA HIROAKI, 西村 勇哉, 五十嵐 一紀, 松本 有, SASAKI RYOHEI, 竹内 俊文
    第40回日本バイオマテリアル学会, Nov. 2018, Japanese, 日本バイオマテリアル学会, 京都, Domestic conference
    Oral presentation

  • In situステルス性獲得にもとづく長期血中滞留性金ナノ粒子内包分子インプリントナノゲルの創製
    北山 雄己哉, 山田 託也, AKASAKA HIROAKI, 西村 勇哉, 五十嵐 一紀, 松本 有, SASAKI RYOHEI, 竹内 俊文
    第40回日本バイオマテリアル学会, Nov. 2018, Japanese, 日本バイオマテリアル学会, 京都, Domestic conference
    Oral presentation

  • 肺不均質ファントムにおける線量計算アルゴリズム精度の検討
    MUKUMOTO NARITOSHI, YADA RYUICHI, 奥村圭祐, 江口力斗, AKASAKA HIROAKI, SHIMIZU YASUYUKI, 大須賀彩希, 西谷隆治, SASAKI RYOHEI
    日本放射線腫瘍学会第31回学術大会, Oct. 2018, Japanese, 日本放射線腫瘍学会, 京都, Domestic conference
    Oral presentation

  • 当院における悪性脳神経膠腫に対するIMRTの治療成績
    ISHIHARA TAKEAKI, 妹尾悟史, AKASAKA HIROAKI, MUKUMOTO NARITOSHI, 井上由子, 西川遼, MIYAWAKI DAISUKE, YOSHIDA KENJI, SASAKI RYOHEI, 篠山隆司, TANAKA KAZUHIRO
    日本放射線腫瘍学会第31回学術大会, Oct. 2018, Japanese, 日本放射線腫瘍学会, 京都, Domestic conference
    Oral presentation

  • 還元型コエンザイムQ10の摂取形状による放射線防護効果の変化
    SHIMIZU YASUYUKI, MUKUMOTO NARITOSHI, MIYAWAKI DAISUKE, 犬伏祥子, AKASAKA HIROAKI, YADA RYUICHI, 大須賀彩希, SASAKI RYOHEI
    日本放射線腫瘍学会第31回学術大会, Oct. 2018, Japanese, 日本放射線腫瘍学会, 京都, Domestic conference
    Poster presentation

  • 放射線治療のための金ナノ粒子内包ステルス性分子インプリントナノゲル
    KITAYAMA YUKIYA, 山田 託也, 木口 健太朗, AKASAKA HIROAKI, 松本 有, SASAKI RYOHEI, TAKEUCHI TOSHIFUMI
    第12回バイオ関連化学シンポジウム, Sep. 2018, Japanese, 日本化学会, 吹田市, Domestic conference
    Poster presentation

  • 放射線治療に用いる金ナノ粒子内包アルブミンインプリントナノゲルの創製
    KITAYAMA YUKIYA, 山田 託也, 木口 健太朗, 吉田 碧衣, AKASAKA HIROAKI, NISHIMURA YUYA, 五十嵐 一紀, 松本 有, SASAKI RYOHEI, TAKEUCHI TOSHIFUMI
    第67回高分子討論会, Sep. 2018, Japanese, 高分子学会, 札幌市, Domestic conference
    Oral presentation

  • 呼吸同期IMRTにおけるInterplay Effectの検討
    MUKUMOTO NARITOSHI, 奥村圭祐, YADA RYUICHI, AKASAKA HIROAKI, SHIMIZU YASUYUKI, 大須賀彩希, 中岡藍, 西谷隆治, SASAKI RYOHEI
    第43回神戸放射線腫瘍懇話会, Sep. 2018, Japanese, 神戸放射線腫瘍懇話会, 神戸, Domestic conference
    Oral presentation

  • 金ナノ粒子内包血清アルブミンインプリントナノゲルの放射線増感効果
    吉田 碧衣, 山田 託也, 木口 健太朗, AKASAKA HIROAKI, SASAKI RYOHEI, KITAYAMA YUKIYA, TAKEUCHI TOSHIFUMI
    第67回高分子討論会, Sep. 2018, Japanese, 高分子学会, 札幌市, Domestic conference
    Poster presentation

  • ガントリー取付式2次元検出器を用いたVMAT検証の可能性・3次元検出器と比較して
    MUKUMOTO NARITOSHI, 奥村圭祐, YADA RYUICHI, AKASAKA HIROAKI, 西谷隆治, SASAKI RYOHEI
    第116回日本医学物理学会学術大会, Sep. 2018, Japanese, 日本医学物理学会, 岩手, Domestic conference
    Oral presentation

  • MOLECULARLY IMPRINTED NANOGELS ACQUIRING STEALTH PROPERTY VIA REGULATING PROTEIN CORONA USING INTRINSIC SERUM ALBUMIN IN SITU
    KITAYAMA Yukiya, YAMADA Takuya, AKASAKA Hiroaki, NISHIMURA Yuya, IGARASHI Kazunori, MATSUMOTO Yu, SASAKI Ryohei, TAKEUCHI Toshifumi
    The 10th International Conference on Molecular Imprinting, Jun. 2018, English, The Society for Molecular Imprinting, Jerusalem,Israel, International conference
    Oral presentation

  • In situステルス性獲得にもとづく長期血中滞留性金ナノ粒子内包分子インプリントナノゲル の創製
    KITAYAMA YUKIYA, 山田 託也, AKASAKA HIROAKI, NISHIMURA YUYA, 五十嵐 一紀, 松本 有, SASAKI RYOHEI, TAKEUCHI TOSHIFUMI
    第34回日本DDS学会学術集会, Jun. 2018, Japanese, 長崎市, Domestic conference
    Poster presentation

  • Application of dual-energy CT to suppression of metal artifacts caused by spinal implant in radiotherapy
    Tianyuan Wang, Takeaki Ishihara, Atsushi Kono, Naoki Yoshida, Noriyuki Negi, Kenichiro Kakutani, Hiroaki Akasaka, Ryuichi Yada, Naritoshi Mukumoto, Daisuke Miyawaki, Kenji Yoshida, Ryohei Sasaki
    World Congress on Medical Physics and Biomedical Engineering 2018, Jun. 2018, English, Prague, International conference
    Oral presentation

  • DDSのための金ナノ粒子含有血清アルブミンインプリントナノゲルの創製
    KITAYAMA YUKIYA, 山田 託也, AKASAKA HIROAKI, 松本 有, SASAKI RYOHEI, TAKEUCHI TOSHIFUMI
    第67回高分子学会年次大会, May 2018, Japanese, 高分子学会, 名古屋市, Domestic conference
    Oral presentation

  • Dosimetric accuracy of dose calculation algorithms for lung heterogeneity phantom
    Naritoshi Mukumoto, Ryuichi Yada, Keisuke Okumura, Hiroaki Akasaka, Yasuyuki Shimizu, Tianyuan Wang, Saki Osuga, Takaharu Nishitani, Yuichi Aoyama, Ryohei Sasaki
    第115回日本医学物理学会学術大会, Apr. 2018, Japanese, 日本医学物理学会, 横浜, Domestic conference
    Oral presentation

  • 頭頸部領域における固定具を用いたCT画像とMR画像のRegistration精度評価
    奥村 圭祐, 椋本 成俊, 京谷 勉輔, 西谷 隆治, 表田 真弓, Akasaka Hiroaki, 青山 裕一, 日下 亜起子
    日本放射線腫瘍学会第30回学術大会, Nov. 2017, Japanese, 日本放射線腫瘍学会, 大阪, Domestic conference
    Poster presentation

  • 当院における低・中リスク前立腺癌に対するヨード永久刺入療法の治療成績
    Yoshida Kenji, Furukawa Jyunya, Miyawaki Daisuke, Ishihara Takeaki, Uezono Haruka, Akasaka Hiroaki, 西谷 隆治, Fujisawa Masato, Sasaki Ryohei
    日本放射線腫瘍学会第30回学術大会, Nov. 2017, Japanese, 日本放射線腫瘍学会, 大阪, Domestic conference
    Poster presentation

  • 当院における低・中リスク前立腺癌に対するヨード永久刺入療法の治療成績
    Yoshida Kenji, Furukawa Jyunya, Miyawaki Daisuke, Ishihara Takeaki, Uezono Haruka, Akasaka Hiroaki, 西谷 隆治, Fujisawa Masato, Sasaki Ryohei
    日本放射線腫瘍学会小線源部会第19回学術大会, Nov. 2017, Japanese, 日本放射線腫瘍学会, 奈良, Domestic conference
    Oral presentation

  • 金ナノ粒子との比較による過酸化チタンナノ粒子の放射線増感効果の有用性の検討
    中山 雅央, Akasaka Hiroaki, 椋本 成俊, 荻野 千秋, 西村 勇哉, 森田 健太, Sasaki Ryohei
    日本放射線腫瘍学会第30回学術大会, Nov. 2017, Japanese, 日本放射線腫瘍学会, 大阪, Domestic conference
    Oral presentation

  • The process of the determination of Dosimetric leaf gap and Transmission for VMAT using TrueBeamTM STx
    Akasaka Hiroaki, Naritoshi Mukumoto, Ryuichi Yada, Tianyuan Wang, Yasuyuki Shimizu, Saki Osuga, Yuichi Aoyama, Sasaki Ryohei
    8th Japan-Korea Joint Meeting on Medical Physics, Nov. 2017, English, 日本医学物理学会, 大阪, International conference
    Oral presentation

  • Novel application of Dual Energy CT for the suppression of metal artifact in Radiotherapy
    王 天縁, Ishihara Takeaki, 吉田 直基, Kakutani Kenichiro, Miyawaki Daisuke, Yoshida Kenji, Akasaka Hiroaki, 椋本 成俊, 矢田 隆一, 青山 裕一, Takahashi Satoru, Sasaki Ryohei
    日本放射線腫瘍学会第30回学術大会, Nov. 2017, English, 日本放射線腫瘍学会, 大阪, Domestic conference
    Poster presentation

  • Influence of the applied voltage on the ion recombination correction factor using the two-voltage technique in FFF beams
    Ryuichi Yada, Naoki Hayashi, Naritoshi Mukumoto, Akasaka Hiroaki, Sasaki Ryohei
    AAPM 59th Annual Meeting & Exhibition, Nov. 2017, English, American Association of Physicists in Medicine, Denver, CO, International conference
    Poster presentation

  • DIRソフトウェアを用いたAdaptive radiation therapyの検討
    椋本 成俊, 矢田 隆一, 清水 康之, 奥村 圭祐, 王 天縁, 大須賀 彩希, Akasaka Hiroaki, 青山 裕一, Sasaki Ryohei
    日本放射線腫瘍学会第30回学術大会, Nov. 2017, Japanese, 日本放射線腫瘍学会, 大阪, Domestic conference
    Oral presentation

  • Assessment of adaptive radiation therapy with deformable image registration software
    Naritoshi Mukumoto, Ryuichi Yada, Yasuyuki Shimizu, Keisuke Okumura, Tianyuan Wang, Saki Osuga, Akasaka Hiroaki, Yuichi Aoyama, Sasaki Ryohei
    AAPM 59th Annual Meeting & Exhibition, Nov. 2017, English, American Association of Physicists in Medicine, Denver, CO, International conference
    Poster presentation

  • Assessment of adaptive radiation therapy with deformable image registration software
    Naritoshi Mukumoto, Ryuichi Yada, Yasuyuki Shimizu, Keisuke Okumura, Tianyuan Wang, Saki Osuga, Akasaka Hiroaki, Toshiaki Minami, Yuichi Aoyama, Sasaki Ryohei
    第113回日本医学物理学会学術大会, Nov. 2017, Japanese, 日本医学物理学会, 横浜, Domestic conference
    Oral presentation

  • 2点電圧法を用いたFFFビームのイオン再結合補正係数の印加電圧の影響
    矢田 隆一, 椋本 成俊, Akasaka Hiroaki, 青山 裕一, 村木 勇太, 安達 由美子, Sasaki Ryohei
    日本放射線腫瘍学会第30回学術大会, Nov. 2017, Japanese, 日本放射線腫瘍学会, 大阪, Domestic conference
    Poster presentation

  • メタボロミクスにおける放射線消化管機能不全指標の解明
    大須賀 彩希, Akasaka Hiroaki, 椋本 成俊, 清水 康之, 王 天縁, Miyawaki Daisuke, Yoshida Kenji, Ishihara Takeaki, Sasaki Ryohei
    日本放射線腫瘍学会第30回学術大会, Oct. 2017, Japanese, 日本放射線腫瘍学会, 大阪, Domestic conference
    Oral presentation

  • 還元型コエンザイムQ10による腸管の有害事象軽減の検討
    清水 康之, 椋本 成俊, Akasaka Hiroaki, 矢田 隆一, 王 天縁, 大須賀 彩希, Miyawaki Daisuke, Sasaki Ryohei
    日本放射線腫瘍学会第30回学術大会, Sep. 2017, Japanese, 日本放射線腫瘍学会, 大阪, Domestic conference
    Poster presentation

  • CT、MRIでの検討に基づく過酸化チタンナノ粒子を用いたTheranostic drugの基礎的検討
    Akasaka Hiroaki, 中山 雅央, 椋本 成俊, 荻野 千秋, 西村 勇哉, 森田 健太, 京谷 勉輔, Sasaki Ryohei
    日本放射線腫瘍学会第30回学術大会, Sep. 2017, Japanese, 日本放射線腫瘍学会, 大阪, Domestic conference
    Poster presentation

  • The process of thedetermination of Dosimetric leaf gap and Transmission for VMAT using TrueBeam STx
    Akasaka Hiroaki, Toshiaki Minami, Ryuichi Yada, Naritoshi Mukumoto, Tianyuan Wang, Shimizu Yasuyuki, Saki Osuga, Yuki Wakahara, Ishihara Takeaki, Yuichi Aoyama, Sasaki Ryohei
    The 29th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2016, Japanese, Japanese Society for Radiation Oncology, 京都, Domestic conference
    Oral presentation

  • Physical analysis of the animal irradiation system in the Kobe University
    Yasuyuki Shimizu, Miyawaki Daisuke, Akasaka Hiroaki, Naritoshi Mukumoto, Masao Nakayama, Tianyuan Wang, Saki Osuga, Yuki Wakahara, Sasaki Ryohei
    The 29th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2016, Japanese, Japanese Society for Radiation Oncology, 京都, Domestic conference
    Poster presentation

  • Next-stage Bioabsorbable Spacer in Particle Therapy
    Tianyuan Wang, Akasaka Hiroaki, Ejima Yasuo, Yoshida Kenji, Miyawaki Daisuke, Ishihara Takeaki, Sachiko Inubushi, Naritoshi Mukumoto, Fukumoto Takumi, Sasaki Ryohei
    The 29th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2016, Japanese, Japanese Society for Radiation Oncology, 京都, Domestic conference
    Poster presentation

  • Experience of IGABT using interstitial needles for locally advanced gynecologic malignancies
    Yoshida Kenji, Ryo Nishikawa, Daisuek Miyawaki, Mayumi Omoteda, Katsusuke Kyotani, Akasaka Hiroaki, Kaori Sasaki, Yoshiro Matsuo, Ebina Yasuhiko, Yamada Hideto, Sasaki Ryohei
    The 29th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2016, Japanese, Japanese Society for Radiation Oncology, 京都, Domestic conference
    Poster presentation

  • Elucidation of the radiation gastrointestinal dysfunction index using metabolomics
    Saki Osuga, Sachiko Inubushi, Ejima Yasuo, Akasaka Hiroaki, Yasuyuki Shimizu, Tianyuan Wang, Naritoshi Mukumoto, Miyawaki Daisuke, Yoshida Kenji, Sasaki Ryohei
    The 29th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2016, Japanese, Japanese Society for Radiation Oncology, 京都, Domestic conference
    Oral presentation

  • Effectiveness of micro-slit beam radiation therapy for multiplelung-metastatic tumor
    Yuki Wakahara, Naritoshi Mukumoto, Masao Nakayama, Akasaka Hiroaki, Ray Corry Uchida, Yoshida Kenji, Ishihara Takeaki, Miyawaki Daisuke, Keiji Umetani, Ejima Yasuo, Sasaki Ryohei
    The 29th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2016, Japanese, Japanese Society for Radiation Oncology, 京都, Domestic conference
    Oral presentation

  • Development of quality management system for LaserLocalizer in Linac
    Yuichi Aoyama, Naritoshi Mukumoto, Takaharu Nishitani, Toshiaki Minami, Mayumi Omoteda, Masanori Miyamoto, Keisuke Okumura, Tomohiro Inoue, Akasaka Hiroaki, Ryuichi Yada, Hideaki Kawamitsu
    The 29th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2016, Japanese, Japanese Society for Radiation Oncology, 京都, Domestic conference
    Poster presentation

  • Comparison of dosimetric parameters in the MRI based IGABT with and without optimization
    Mayumi Omoteda, Yoshida Kenji, Ryo Nishikawa, Katsusuke Kyotani, Miyawaki Daisuke, Akasaka Hiroaki, Ebina Yasuhiko, Yamada Hideto, Takahashi Satoru, Yuichi Aoyama, Sasaki Ryohei
    The 29th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2016, Japanese, Japanese Society for Radiation Oncology, 京都, Domestic conference
    Poster presentation

  • Assessment of dose calculation accuracy with lung heterogeneity phantom
    Naritoshi Mukumoto, Ryuichi Yada, Keisuke Okumura, Takuro Nishio, Akasaka Hiroaki, Yasuyuki Shimizu, Takaharu Nishitani, Yuichi Aoyama, Miyawaki Daisuke, Sasaki Ryohei
    The 29th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2016, Japanese, Japanese Society for Radiation Oncology, 京都, Domestic conference
    Poster presentation

  • A case of uterine cervical cancer presenting with dermatomyositis as a paraneoplastic syndrome
    Kaori Sasaki, Yoshida Kenji, Miyawaki Daisuke, Yoshiro Matsuo, Ryo Nishikawa, Ishihara Takeaki, Ejima Yasuo, Akasaka Hiroaki, Yoshiya Miyawaki, Ueda Takehiro, Sasaki Ryohei
    The 29th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2016, Japanese, Japanese Society for Radiation Oncology, 京都, Domestic conference
    Poster presentation

  • 肺不均質ファントムにおける線量計算アルゴリズム精度の検討
    椋本成俊, 矢田隆一, Akasaka Hiroaki, 清水康之, 奥村圭祐, 王天縁, 大須賀彩希, 若原悠希, 青山裕一, Sasaki Ryohei
    The 112th Annual Meeting of the Japanese Society of Medical Physics, Sep. 2016, Japanese, Japanese Society of Medical Physics, 沖縄, Domestic conference
    Poster presentation

  • One-year Experience of MRI Based Image Guided Adaptive Brachytherapy for Cervical Cancer
    Ryo Nishikawa, Yoshida Kenji, Miyawaki Daisuke, Yoshiro Matsuo, Akasaka Hiroaki, Mayumi Omoteda, Katsusuke Kyotani, Fumie Ota, Takahashi Satoru, Hitoaki Satoh, Ebina Yasuhiko, Yamada Hideto, Sasaki Ryohei
    The 75th Annual Meeting of the Japan Radiological Society, Apr. 2016, Japanese, Japan Radiological Society, 横浜, Domestic conference
    Poster presentation

  • Discovery of novel Index of radiation gastrointestinal disorders via metabolomics
    S Osuga, S Inubushi, Ejima Yasuo, Akasaka Hiroaki, Miyawaki Daisuke, Sasaki Ryohei
    The 4th International Symposium of Training Plan for Oncology Professionals, Feb. 2016, English, 大阪, International conference
    Oral presentation

  • Assessment of Apparent Diffusion Coefficient during Image Guided Adaptive Brachytherapy for the Prediction of Local Controllability in Cervical Cancer Treatment: A preliminary histogram analysis
    Ryo Nishikawa, Yoshida Kenji, Miyawaki Daisuke, Akasaka Hiroaki, Takahashi Satoru, Mayumi Omoteda, Katsusuke Kyotani, Sasaki Ryohei
    The 4th International Symposium of Training Plan for Oncology Professionals, Feb. 2016, English, 大阪, International conference
    Poster presentation

  • Response of multiple lung-metastatic tumor to microplanar beam irradiation
    Naritoshi Mukumoto, Masao Nakayama, Akasaka Hiroaki, Ray Cory Uchida, Keiji Umetani, Nobuteru Nariyama, Ishihara Takeaki, Miyawaki Daisuke, Yoshida Kenji, Ejima Yasuo, Sasaki Ryohei
    The 28th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2015, Japanese, JASTRO, 群馬, Domestic conference
    Oral presentation

  • Improvement of Abdominal Radiation-induced Anorexia by Rikkunshito
    Y Shimizu, Miyawaki Daisuke, N Mukumoto, R Uchida, Akasaka Hiroaki, Ishihara Takeaki, Yoshida Kohsuke, Ejima Yasuo, Sasaki Ryohei
    The 28th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2015, Japanese, JASTRO, 群馬, Domestic conference
    Poster presentation

  • How changes of Auto beam modeling in TPS according to difference Geometric Resolutions ?
    Yuichi Aoyama, Naritoshi Mukumoto, Takaharu Nishitani, Toshiaki Minami, Mayumi Omoteda, Naoki Yoshida, Akasaka Hiroaki, Kuniyasu Okudaira, Hiroshi Oguchi, Hideaki Kawamitsu
    The 28th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2015, Japanese, JASTRO, 群馬, Domestic conference
    Oral presentation

  • Effects of the synchrotron X-ray microbeam spacing on mouse normal brain tissue
    Masao Nakayama, Naritoshi Mukumoto, Akasaka Hiroaki, Miyawaki Daisuke, Hideki Nishimura, Keiji Umetani, Takeshi Kondoh, Sasaki Ryohei
    The 28th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2015, Japanese, JASTRO, 群馬, Domestic conference
    Oral presentation

  • Early Experience of Image Guided Adaptive Brachytherapy using Magnetic Resonance Imaging
    Yoshida Kenji, Miyawaki Daisuke, Yoshiro Matsuo, Ryo Nishikawa, Akasaka Hiroaki, Mayumi Omoteda, Katsusuke Kyotani, Fumie Ota, Takahashi Satoru, Hitoaki Satoh, Ebina Yasuhiko, Yamada Hideto, Sasaki Ryohei
    The 28th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2015, English, JASTRO, 群馬, Domestic conference
    Oral presentation

  • A Future Radiosensitizor from the Spinach, MGDG, Induced Apoptosis in the Pancreatic Cancer Cells Combined with Radiation In vitro and In vivo
    Akasaka Hiroaki, Ejima Yasuo, Yoshida Kenji, Miyawaki Daisuke, Ishihara Takeaki, Naritoshi Mukumoto, Yoshiro Matsuo, Haruka Uezono, Yoshiyuki Mizushina, Sasaki Ryohei
    The 28th Annual Meeting of the Japanese Society for Radiation Oncology, Nov. 2015, Japanese, JASTRO, 群馬, Domestic conference
    Oral presentation

  • 新規体内吸収性スペーサーを用いた腹部放射線治療法の基礎開発検討
    Akasaka Hiroaki
    第3回神緑会YIA発表会, Oct. 2015, Japanese, 神緑会, 神戸, Domestic conference
    Poster presentation

  • A Novel Radiosensitizor from the Component of Spinach, MGDG, Induced Apoptosis in the Pancreatic Cancer Cells Combined with Radiation
    Akasaka Hiroaki, Ejima Yasuo, Yoshida Kenji, Miyawaki Daisuke, Ishihara Takeaki, Naritoshi Mukumoto, Yoshiro Matsuo, Haruka Uezono, Yoshiyuki Mizushina, Sasaki Ryohei
    ASTRO 57th Annual Meeting, Oct. 2015, English, ASTRO, San Antonio, USA, International conference
    Poster presentation

  • 当院におけるMRIを用いた婦人科癌画像誘導小線源治療の運用と初期経験
    Yoshida Kenji, Miyawaki Daisuke, 松尾圭朗, 西川遼, 表田真弓, 京谷勉輔, Akasaka Hiroaki, 大田史江, Sato Hitoaki, Ebina Yasuhiko, Yamada Hideto, Takahashi Satoru, Sasaki Ryohei
    神戸放射線腫瘍懇話会, Sep. 2015, Japanese, 神戸, Domestic conference
    Oral presentation

  • Volumetric modulated arc therapy (VMAT) for head and neck cancer: A planning study on our institution
    T.Y. Wang, Ishihara Takeaki, Ejima Yasuo, Yoshida Kohsuke, Miyawaki Daisuke, Y.Matsuo, R.Nishikawa, Inoue Yukako, Akasaka Hiroaki, N.Mukumoto, Y.Shimizu, S.Osuga, Sasaki Ryohei
    第56回JROG 関西若手放射線治療勉強会, Jun. 2015, Japanese, JROG, 奈良, Domestic conference
    Oral presentation

  • A Novel method of Radioprotection for the Gastointestinal System: Efficacy of the reduced form of Coenzyme Q10.
    Saki Osuga, Naritoshi Mukumoto, Nelly Binti Idrus, Ray Uchida, Akasaka Hiroaki, Miyawaki Daisuke, Yoshiro Matsuo, Ejima Yasuo, Mitsuaki Kitano, Hiroshi Kubo, Hideyuki Kishida, Yasuda Takahiro, Sasaki Ryohei
    4th Congress of Asian Society of Head and Neck Oncology, 39th Annual Meeting of Japan Society for Head and Neck Cancer, Jun. 2015, English, Japan Society for Head and Neck Cancer, 神戸, International conference
    Poster presentation

  • A Future Method: Space Modulated Particle Therapy (SMPT) Using a Novel Bioabsorbable Spacer
    Akasaka Hiroaki, Fukumoto Takumi, Miyawaki Daisuke, Naritoshi Mukumoto, Wang Tien Yuan, Shigeru Yamada, Masao Murakami, Yusuke Demizu, Sasaki Ryohei
    The 3rd Japan-Taiwan Radiation Oncology Symposium, Jun. 2015, English, The 3rd Japan-Taiwan Radiation Oncology Symposium, 山梨, International conference
    Oral presentation

  • Tolerance for Micro-slit beam X-ray radiation to Central Nervous System
    Naritoshi Mukumoto, Akasaka Hiroaki, Masao Nakayama, Miura Yasushi, Miyawaki Daisuke, Keiji Umetani, Nobuteru Nariyama, Kunio Shinohara, Takeshi Kondoh, Sasaki Ryohei
    15th International Congress of Radiation Research, May 2015, English, ICRR, 京都, International conference
    Poster presentation

  • Radiosensitizor extracted from Spinach, MGDG, Enhanced the Cytotoxic Effect for Pancreatic Cancer Cells when combined with Radiation Treatment
    Akasaka Hiroaki, Ejima Yasuo, Yoshida Kenji, Miyawaki Daisuke, Ishihara Takeaki, Yoshiyuki Mizushina, Sasaki Ryohei
    15th International Congress of Radiation Research, May 2015, English, ICRR, 京都, International conference
    Poster presentation

  • Next-stage Bioabsorbable Spacer in Particle Therapy
    T.Y. Wang, Akasaka Hiroaki, Ejima Yasuo, Yoshida Kohsuke, Miyawaki Daisuke, Ishihara Takeaki, N Mukumoto, Fukumoto Takumi, Sasaki Ryohei
    15th International Congress of Radiation Research, May 2015, English, 京都, International conference
    Poster presentation

■ Research Themes
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