Research activity information

• Apr. 2024 The Chemical Society of Japan, Student Presentation Award, The 104th CSJ Annual Meeting (2024), Gram-Scale Synthesis of Carbazomycin A–D

  Yuxuan Feng

• Precise Control of Charge–Structure Coupling in Polyamide Membranes for Mono‐ and Divalent Ion Separation

  Shaofan Duan, Shuai Jiang, Feidong Yang, Yuxuan Feng, Yongxuan Shi, Pengfei Zhang, Mengyang Hu, Yuqing Lin, Tae Hoon Lee, Kecheng Guan, Keizo Nakagawa, Tomohisa Yoshioka, Hideto Matsuyama, Eiji Kamio

  Aug. 2026, Advanced Science

  Scientific journal


• Highly Efficient and Stable Ni–W Nanoalloy Catalyst for Selective Hydrogenation of Nitriles to Secondary Amines

  Taiki Kawakami, Yuxuan Feng, Kentaro Okano, Sho Yamaguchi

  American Chemical Society (ACS), Jul. 2026, ACS Catalysis

  [Refereed]

  Scientific journal


• Regioselective Deprotonative Metalation of Heteroarenes with a Combination of Lithium Amide and Zinc Chloride Diamine Complex

  Yuxuan Feng, Atsunori Mori, Kentaro Okano

  Lead, American Chemical Society (ACS), Aug. 2025, The Journal of Organic Chemistry, 90(33) (33), 12007 - 12016

  [Refereed]

  Scientific journal


• Gram-Scale Total Synthesis of Carbazomycins A–D through Late-Stage Regioselective Demethylation of Aryl Methyl Ethers

  Yuxuan Feng, Atsunori Mori, Kentaro Okano

  Lead, American Chemical Society (ACS), Sep. 2024, The Journal of Organic Chemistry, 89(18) (18), 13472 - 13484

  [Refereed]

  Scientific journal


• Total Synthesis of Carbazomycins E and F

  Yunosuke Shima, Yuxuan Feng, Atsunori Mori, Kentaro Okano

  May 2024, The Journal of Organic Chemistry, 89(11) (11), 8185 - 8191, English

  [Refereed]

  Scientific journal


• Deprotonative Generation and Trapping of Haloaryllithium in a Batch Reactor

  Yuxuan Feng, Taro Yukioka, Mei Matsuyama, Atsunori Mori, Kentaro Okano

  Lead, American Chemical Society (ACS), Apr. 2023, Organic Letters, 25(17) (17), 3013 - 3017

  [Refereed]

  Scientific journal


• “Snapshot” Trapping of Multiple Transient Azolyllithiums in Batch

  Kengo Inoue, Yuxuan Feng, Atsunori Mori, Kentaro Okano

  Abstract Recent developments in flow microreactor technology have allowed the use of transient organolithium compounds that cannot be realized in a batch reactor. However, trapping the transient aryllithiums in a “halogen dance” is still challenging. Herein is reported the trapping of such short‐lived azolyllithiums in a batch reactor by developing a finely tuned in situ zincation using zinc halide diamine complexes. The reaction rate is controlled by the appropriate choice of diamine ligand. The reaction is operationally simple and can be performed at 0 °C with high reproducibility on a multigram scale. This method was applicable to a wide range of brominated azoles allowing deprotonative functionalization, which was used for the concise divergent syntheses of both constitutional isomers of biologically active azoles.

  Wiley, May 2021, Chemistry – A European Journal, 27(40) (40), 10267 - 10273

  [Refereed]

  Scientific journal