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UNENO Yu
University Hospital / Palliative Medicine
Professor

Researcher basic information

■ Research Keyword
  • Palliative Care
  • Complex Intervention
  • がん悪液質
  • がん代謝
  • 遺族ケア・グリーフケア
■ Committee History
  • Jun. 2026 - Present, 日本緩和医療学会, 理事
  • Dec. 2024 - Present, PLOS ONE, Editorial Board, Academic Editor.
  • Nov. 2024 - Present, Members
  • Oct. 2024 - Present, Japanese Journal of Clinical Oncology, Reviewer Board.
  • Sep. 2024 - Present, 日本緩和医療学会, 会員管理システム構築WPG WPG員
  • Aug. 2024 - Present, 日本緩和医療学会, 専門医育成・教育委員会 副委員長
  • Jul. 2024 - Present, 日本カヘキシア・サルコペニア学会, 評議員
  • Jul. 2024 - Present, 日本がんサポーティブケア学会, Cachexia部会 部会員
  • Apr. 2024 - Present, 日本がんサポーティブケア学会, 評議員
  • Feb. 2024 - Present, 日本緩和医療学会, 代議員
  • Oct. 2023 - Present, 日本緩和医療学会, Faculty Development WPG WPG員長
  • Aug. 2023 - Present, 日本緩和医療学会, 輸液ガイドライン改訂WPG デルファイ担当者
  • Apr. 2023 - Present, 日本がんサポーティブケア学会, Integration of oncology and palliative care (IOP) WG WG長
  • Nov. 2022 - Present, 日本緩和医療学会, がん疼痛薬物療法ガイドライン改訂WPG WPG員
  • Aug. 2022 - Present, 日本緩和医療学会, 研修指導者講習会WPG WPG員
  • Aug. 2022 - Present, 日本緩和医療学会, 学術大会支援メンバーWG WG員
  • Aug. 2022 - Present, 日本緩和医療学会, 専門医育成・教育委員会 委員
  • Aug. 2022 - Present, 日本緩和医療学会, 専門医認定員会 委員
  • 2017 - Mar. 2023, 日本がんサポーティブケア学会, Integration of oncology and palliative care (IOP) WG WG員
  • Aug. 2020 - Jul. 2022, 日本緩和医療学会, 専門医認定・育成委員会 委員

Research activity information

■ Award
  • Oct. 2025 日本サイコオンコロジー学会, 教育功労賞

  • Sep. 2024 IPOS 2024, Special poster flits

  • Jun. 2024 日本緩和医療学会, 2023年査読功労賞 (Palliative Care Research)

  • Jun. 2024 第29回日本緩和医療学会学術大会・第37回日本サイコオンコロジー学会総会 合同学術大会, 最優秀演題賞

  • Nov. 2021 Top abstract award, 14th Asia Pacific Hospice Palliative Care Conference

  • Oct. 2018 European Society for Medical Oncology, ESMO 2018 Merit Award

  • Dec. 2016 European Society for Medical Oncology, ESMO Asia 2016 Travel Grant Award

  • Oct. 2016 European Society for Medical Oncology, ESMO 2016 Palliative Care Research Fellowship Award

■ Paper
  • Yo Ishihara, Mayumi Ohira, Mitsuki Hokabe, Sadaaki Yoshino, Kohei Iwashita, Kota Takahashi, Naoki Tomita, Yu Uneno, Shigeki Kataoka, Takeo Kurihashi, Eriko Satomi, Jun Hamano, Takahiro Higashibata, Kazuhiro Kosugi, Mami Hirakawa, Shinya Kajiura, Suguru Ogihara, Masaki Kida, Tatsuya Morita, Yuichi Koretaka, Takuhiro Sonoyama, Shunsuke Oyamada, Atsushi Nakajima, Takaomi Kessoku
    INTRODUCTION: Opioid-induced nausea and vomiting (OINV) in patients with cancer imposes a substantial clinical burden and may compromise adherence to opioid therapy. Naldemedine, a peripheral μ-opioid receptor antagonist, is currently approved for the treatment of opioid-induced constipation. Recent evidence suggests similar benefits for the treatment of OINV. This study aims to evaluate the preventive effect of naldemedine on OINV in patients with cancer pain initiating opioid analgesics. METHODS AND ANALYSIS: This multicentre, double-blind, randomised, placebo-controlled, parallel-group comparison trial will be conducted across 20 hospitals and clinics in Japan. An estimated 120 patients with cancer scheduled to initiate opioid analgesic therapy will be recruited and randomly assigned (1:1) to receive either naldemedine or placebo on day 1 (visit 1). From days 1 to 7, patients will receive blinded study medication concurrently with opioid analgesics and will be followed for 8 days. The primary endpoint will be the proportion of patients achieving a complete response (CR) on day 5, defined as no vomiting and no use of rescue antiemetics for up to 120 hours after initiation of opioid analgesics. Key secondary endpoints will include the proportion of patients achieving CR on days 1, 2, 3 and 7; changes in Numerical Rating Scale scores from baseline; duration of nausea; proportion of patients who experience vomiting; proportion of patients using rescue antiemetics and frequency of rescue antiemetic use. Additionally, the incidence of adverse events and serious adverse events will be recorded throughout the observation period. ETHICS AND DISSEMINATION: This study has been reviewed and approved by the Hattori Clinic Certified Review Board (approval number: CRB3180027). Written informed consent will be obtained from all participating patients before study commencement. The results of the study will be presented at academic conferences in Japan or overseas and submitted for publication in a peer-reviewed journal. TRIAL REGISTRATION NUMBER: NCT07038551 and jRCTs031250128.
    Jul. 2026, BMJ open, 16(7) (7), e114092, English, International magazine
    Scientific journal

  • Masanori Mori, Tatsuya Morita, Keiko Tamura, Kengo Imai, Toshihiro Yamauchi, Misuzu Yuasa, Satoru Miwa, Kentaro Watanabe, Soichiro Okamoto, Yu Uneno, Satoshi Inoue, Sayuri Itoga, Kaori Fukuta, Emi Kiyohara, Naosuke Yokomichi, Yumi Sakuma, Koichi Sugiyama, Akemi Shirado Naito, Hiroyuki Otani, Jun Hamano, Yusuke Hiratsuka, Maho Aoyama, Satoru Tsuneto, Ryoka Ishida, Mitsunori Miyashita
    Background: Unfinished business (UB) and related distress are associated with adverse bereavement outcomes, yet practical strategies remain limited. Objectives: To explore differences in UB-related outcomes across pre- and post-quality improvement (QI) periods. Methods: Pre- and post-QI surveys were conducted among bereaved families of advanced cancer patients at a 27-bed hospice in Japan. The intervention included a one-page pamphlet at admission and clinician attention to prognostic awareness and emotional preparation. Outcomes included the Unfinished Business in Bereavement Scale (UBBS), UB-related distress, and Good Death Inventory domains. Independent samples t -tests with effect sizes (ESs) were used. Results: Valid responses were obtained from 319 pre-QI and 216 post-QI families. UBBS scores (mean 12.46 vs. 11.24; ES = 0.29; p = 0.001) and UB-related distress (4.73 vs. 4.31; ES = 0.25; p = 0.005) were lower, and life completion scores were higher (4.13 vs. 4.50; ES = −0.24; p = 0.007) in the post-QI cohort. Conclusions: The post-QI period was associated with lower UB-related distress, supporting the need for further intervention research.
    SAGE Publications, Jan. 2026, Palliative Medicine Reports, 7
    [Refereed]
    Scientific journal

  • Daisuke Fujisawa, Eisho Yoshikawa, Maiko Fujimori, Sachiko Arai, Makoto Kobayakawa, Akiko Kurata, Ayako Kayano, Kanako Ichikura, Yuri Igarashi, Hiroyuki Otani, Yuko Yanai, Tomoko Baba, Yoshiro Okajima, Akiko Abe, Yu Uneno, Masako Okamura, Yoshihisa Matsumoto, Kurumi Asaumi, Kazuho Hisamura, Kanae Momino, Emi Takeuchi, Atsushi Sato, Noriko Tamura, Akiko Imai, Ryoichi Sadahiro, Toru Okuyama
    Abstract Objectives This article aims to describe the newly developed Japanese practice guidelines for psychological distress of adult individuals with cancer who have elevated levels of psychological distress. Methods We conducted systematic reviews and Delphi consensus rounds to determine the levels of certainty of evidence and strength of recommendation. Results In our proposed flow of care, all individuals with cancer should initially be provided with general support, comprising supportive communication, detection of psychological distress, attendance to their needs, and differentiating physical conditions that mimic psychological distress. If a patient still has significant psychological distress despite such support, more specific care for psychological distress should be considered. Collaborative care has strong evidence base and is strongly recommended. Evidence for psychotherapy for psychological distress and fear of cancer recurrence is moderate to strong, however, recommendations for these interventions were weakened because of the heterogeneity of interventions and lack of formal training system. Evidence of pharmacotherapy was weak. Thus, anxiolytics are weakly recommended only for short term and should be accompanied with psychosocial support. Antidepressants are weakly recommended when a patient is diagnosed with depression. Early specialized palliative care, care for caregivers and peer support are not recommended as a sole means to alleviate psychological distress, due to the scarce supporting evidence. Provision of these interventions is not hindered when they aim to improve the outcomes other than psychological distress, such as quality of life, symptom burden and self-efficacy. Discussion New practice guidelines for psychological distress of adult individuals with cancer have been developed.
    Oxford University Press (OUP), Dec. 2025, Japanese Journal of Clinical Oncology
    [Refereed]
    Scientific journal

  • Takaaki Hasegawa, Toru Okuyama, Ryoichi Sadahiro, Yu Uneno, Yoshiaki Okamoto, Yusuke Kanno, Saho Wada, Shuji Inada, Yuri Igarashi, Hitoshi Tanimukai, Daisuke Fujisawa
    Elsevier BV, Oct. 2025, Journal of the Academy of Consultation-Liaison Psychiatry
    [Refereed]
    Scientific journal

  • Hitoya Sano, Takuya Odagiri, Keita Tagami, Yu Uneno, Manabu Muto
    PURPOSE: To clarify the preferred timing and contents of early palliative care and preference for continued care delivery among patients with advanced cancer in Japan. METHODS: We conducted an Internet-based anonymous questionnaire survey on adult patients with advanced cancer. We assessed the patients' wishes for palliative care delivered by a team or at outpatient clinics while asymptomatic, as well as the preferred intervention timing and preference for continuing care lifelong. Palliative care contents, cancer status, understanding and goals of cancer treatment, symptoms, and background factors were compared among these three preferences. RESULTS: In total, 531 patients responded (mean age, 61 years; men, 70%; major primary cancer sites, urological tract and breast), of whom 345 patients (65%) wished for palliative care while asymptomatic, and multivariate analysis revealed that a desire to address daily living and financial issues; wishing for consultations regarding illness, treatment, and end-of-life care; young age; primary sites other than hematological or urological sites; and increased physical distress were significantly associated with this wish. Approximately 51.3% of patients preferred palliative care before completing cancer treatment, while 40% preferred continuing palliative care lifelong. Young patients preferred early palliative care, and patients with a desire to address social distress preferred continuing palliative care. CONCLUSION: The results highlight the importance of early palliative care planning in patients with advanced cancer; however, evaluating the eligibility for palliative care is essential.
    Sep. 2025, Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 33(10) (10), 841 - 841, English, International magazine
    [Refereed]
    Scientific journal

  • Haruka Tani, Misako Yamada, Shoko Sugao, Yasuhiro Kotera, Yu Uneno
    Abstract Background Bereavement-related grief and prolonged grief disorders are highly prevalent; however, standardised care approaches are lacking. To address this gap, the self-COMPAssion-based online group psyChoTherapy for bereavement-related grief (COMPACT) feasibility trial was developed; it showed promising participant engagement and potential effectiveness. This study aimed to elucidate the mechanisms underlying the impact, contextual factors, and implementation considerations of the COMPACT programme. Methods Online semi-structured interviews were conducted and analysed using a deductive reflexive thematic analysis guided by the UK Medical Research Council process evaluation framework. The interviews involved 21 participants and 10 intervention personnel from the COMPACT feasibility trial. The Helpful Aspects of Therapy Form (HATF) was used to guide the interviews, ensuring a focus on identifying mechanisms of impact, contextual factors, and implementation considerations. Results Four main “mechanism of impact” themes were identified: common humanity and self-awareness, perceived importance of self-care, deepening self-insights and personal growth, and amplified self-compassion. Two associated “contextual factor” themes (group therapy and a secure programme environment) were highlighted. Additionally, two “implementation consideration” themes (barriers and facilitators) were found, with related contextual themes of group therapy and online delivery. Conclusions The core impact mechanisms of the COMPACT programme included accessible online delivery, group work enhancing common humanity, and a safe, supportive environment deepening self-insight, self-care, and self-compassion. Future research should prioritise refining programme content, improving participant assessment, and enhancing training for intervention personnel to enable a randomised controlled trial testing the effectiveness of the intervention. Trial registration UMIN000048554, registered 2nd August 2022.
    Last, Springer Science and Business Media LLC, May 2025, BMC Palliative Care, 24(1) (1)
    [Refereed]
    Scientific journal

  • Koji Amano, Satomi Okamura, Naoharu Mori, Tatsuma Sakaguchi, Tomofumi Miura, Yu Uneno, Hiroto Ishiki, Yusuke Hiratsuka, Naosuke Yokomichi, Jun Hamano, Masanori Mori, Tatsuya Morita
    Elsevier BV, Apr. 2025, Nutrition, 112818 - 112818
    [Refereed]
    Scientific journal

  • Masano Sagawa, Ryota Matsui, Akihiko Sano, Makoto Sakai, Shinichiro Hiraoka, Isao Tabei, Takayuki Imai, Hideo Matsumoto, Seiji Onogawa, Norihiro Sonoi, Shigeyuki Nagata, Ryo Ogawa, Shigeki Wakiyama, Yasuhiro Miyazaki, Koshi Kumagai, Rie Tsutsumi, Takehiro Okabayashi, Yu Uneno, Naoki Higashibeppu, Joji Kotani
    Elsevier BV, Apr. 2025, Clinical Nutrition ESPEN
    [Refereed]
    Scientific journal

  • Koji Amano, Satomi Okamura, Tomofumi Miura, Vickie E. Baracos, Naoharu Mori, Tatsuma Sakaguchi, Yu Uneno, Hiroto Ishiki, Yusuke Hiratsuka, Naosuke Yokomichi, Jun Hamano, Mika Baba, Masanori Mori, Tatsuya Morita
    Mary Ann Liebert Inc, Feb. 2025, Journal of Palliative Medicine
    [Refereed]
    Scientific journal

  • Yuki Kondo, Shinya Ohashi, Chikatoshi Katada, Yukie Nakai, Yoshihiro Yamamoto, Masashi Tamaoki, Osamu Kikuchi, Atsushi Yamada, Kenshiro Hirohashi, Yosuke Mitani, Shigeki Kataoka, Tomoki Saito, Trang H. Nguyen Vu, Tomohiro Kondo, Yu Uneno, Tomohiko Sunami, Akira Yokoyama, Junichi Matsubara, Tomonari Matsuda, Seiji Naganuma, Kohei Oryu, Samuel Flashner, Masataka Shimonosono, Hiroshi Nakagawa, Manabu Muto
    Abstract Background Field cancerization defined by multiple development of squamous cell carcinomas (SCCs) in upper aerodigestive tract was explained by excessive alcohol intake. A dysfunctional mitochondrial aldehyde dehydrogenase 2 (Aldh2) delays the clearance of acetaldehyde, a genotoxic alcohol metabolite, and increases SCC risks. TP53 plays key roles in squamous carcinogenesis. However, the mechanism of alcohol-mediated squamous field cancerization has not been clearly elucidated. Methods We developed a novel genetically engineered mouse strain KTPA –/– (Krt5Cre ERT2 ; Trp53 loxp/loxp ; Aldh2 –/–) featuring Aldh2-loss concurrent with epithelial-specific Trp53 deletion. These mice were given 10%-EtOH, and we evaluated the development of squamous cell carcinogenesis histologically and genetically. Results Widespread multifocal rete ridges (RRs), characterized by downward growth of proliferative preneoplastic cells, were found only in Aldh2 +/– and Aldh2 –/– mice with keratin5-specific Trp53 deletion (KTPA +/– and KTPA –/– mice, respectively), and alcohol drinking apparently increased RR formation rate. SCC occurred only in KTPA –/– (Aldh2 loss/TP53 loss) mice with alcohol drinking (15/18: 83%). Total alcohol consumption volume was significantly higher in KTPA –/– (Aldh2 loss/TP53 loss) mice with SCCs than those without SCCs. Further, target sequence revealed the occurrence of genetic abnormalities including Trp53 mutations in the esophageal epithelium of Aldh2 –/– mice with alcohol drinking, suggesting direct mutagenic effects of alcohol drinking to the esophageal epithelium. Conclusion This study provides for the first time the evidence that alcohol drinking, Aldh2 dysfunction and Trp53 loss cooperate in squamous field cancerization. Alcohol consumption volume affects the SCCs development, even in the same genotype.
    Springer Science and Business Media LLC, Feb. 2025, Journal of Gastroenterology
    [Refereed]
    Scientific journal

  • Sayaka Takenouchi, Yu Uneno, Shigemi Matsumoto, Ai Chikada, Ryuji Uozumi, Tomoko Izawa, Sayako Ouchi, Takako Kuroda, Yu Hidaka, Hitoshi Tanimukai, Motoo Nomura, Manabu Muto, Keiko Tamura, Satoru Tsuneto, Yoshiyuki Kizawa, Tatsuya Morita, Masanori Mori
    Elsevier BV, Dec. 2024, Journal of Pain and Symptom Management, 68(6) (6), 548 - 560.e2
    [Refereed]
    Scientific journal

  • Yu Uneno, Yasuhiro Kotera, Kyoko Kikuchi, Misako Yamada, Mari Sugitani, Saori Terado, Hiroko Maehara, Yuri Sakamoto, Shoko Sugao, Haruka Tani, Akiko Shimizu, Yoko Kubo, Daisuke Fujisawa, Manabu Muto
    Elsevier BV, Sep. 2024, General Hospital Psychiatry, 90, 116 - 123
    [Refereed]
    Scientific journal

  • Yu Uneno, Masanori Mori, Junko Saito, Aki Otsuki, Aya Kuchiba, Naomi Sakurai, Naoki Nakaya, Maiko Fujimori, Taichi Shimazu
    Abstract Background The diversification of information sources and changes in social structures necessitates updates on the state of public awareness of palliative care. Therefore, we clarified the status and determinants of awareness, information sources, and beliefs, regarding palliative care in Japan. Methods This nationwide cross-sectional survey included 10 000 participants aged ≥20 years enrolled through random sampling using a two-stage stratification in 2023. We used a mailed self-administered questionnaire (INFORM Study 2023). The questionnaire items were selected (partially modified) from the Health Information National Trends Survey (USA) to ensure comparability, included palliative care awareness, information sources, and beliefs. Weighted logistic regression was conducted to explore the determinants of awareness. Results Of the 3452 participants that responded (response rate: 35.3%), 65.2% had palliative care awareness. The weighted logistic regression analysis revealed that respondents less likely to have any palliative care awareness were younger, were male, had limited education history, had lower household income, and were non-Internet users. Of these, sex had the clear association (adjusted odds ratio for female vs. male: 3.20 [95% CI: 2.66–3.85]). Across all age groups, healthcare professionals (58.5%) and the Internet (30.5%) were the most trusted source of information. Younger participants frequently received information online. Most participants believed that palliative care was beneficial, although 82.0% associated it with death. Conclusions The Japanese population had a relatively high palliative care awareness, with the majority trusting information from healthcare professionals rather than the Internet. Further efforts are warranted to address barriers to receiving trustworthy palliative care information.
    Oxford University Press (OUP), Jul. 2024, Japanese Journal of Clinical Oncology, 54(11) (11), 1171 - 1179
    [Refereed]
    Scientific journal

  • Hideo Matsumoto, Seiji Onogawa, Norihiro Sonoi, Masano Sagawa, Shigeki Wakiyama, Ryo Ogawa, Yasuhiro Miyazaki, Shigeyuki Nagata, Takehiro Okabayashi, Susumu Tazuma, Akihiko Futamura, Yu Uneno, Naoki Higashibeppu, Joji Kotani
    Introduction: Healthy eating and weight control are recommended for cancer survivors; however, dietary interventions are not routinely offered to them. This study aimed to assess the effects of dietary interventions on survival, nutritional status, morbidity, dietary changes, health-related quality of life (QOL), and clinical measures in cancer survivors. Methods: Searches were conducted from October 1, 2018 to November 21, 2011 in the Medline, EMBASE, CENTRAL, Emcare, and DARE electronic databases. We included randomized controlled trials (RCTs) that involved individuals diagnosed with cancer, excluding conference abstracts, case studies, other reviews, and meta-analyses, and screened the articles. Results: Eight studies were included in this meta-analysis. We observed significant improvements in QOL and clinical data in 3 of 6 studies and in one study, respectively, significant weight loss on anthropometry in 2 of 5 studies, and dietary improvement in 4 of 5 studies of adult cancer survivors. However, we did not observe any benefits of dietary intervention for cancer survivors with undernutrition. Discussion: Dietary interventions for adult cancer survivors might contribute to improving their nutritional status; however, further clarification requires a study that standardizes the intervention method. Furthermore, RCTs are required to determine the effects on cancer survivors with undernutrition.
    Ovid Technologies (Wolters Kluwer Health), Jun. 2024, Medicine, 103(26) (26), e38675 - e38675
    [Refereed]
    Scientific journal

  • Yu Uneno, Keita Fukuyama, Ayumi Nishimura, Kana Eguchi, Hideki Kojima, Takeshi Umino, Kikuko Miyazaki, Eiju Negora, Keiko Minashi, Osamu Sugiyama, Taichi Shimazu, Manabu Muto, Shigemi Matsumoto
    Springer Science and Business Media LLC, Apr. 2024, Cureus, 16(4) (4), e58611
    [Refereed]
    Scientific journal

  • Koji Amano, Satomi Okamura, Vickie E. Baracos, Naoharu Mori, Tatsuma Sakaguchi, Yu Uneno, Yusuke Hiratsuka, Jun Hamano, Tomofumi Miura, Hiroto Ishiki, Naosuke Yokomichi, Yutaka Hatano, Tatsuya Morita, Masanori Mori
    Elsevier BV, Apr. 2024, Clinical Nutrition ESPEN, 60, 373 - 381
    [Refereed]
    Scientific journal

  • Yu Uneno, Motoo Nomura, Taisuke Hosokai, Yoshinosuke Kurakake, Masayuki Fuki, Hiroki Shiomi, Yasuhide Takeuchi, Masashi Tamaoki, Akira Yokoyama, Chikatoshi Katada, Manabu Muto
    Japanese Society of Internal Medicine, Mar. 2024, Internal Medicine, 63(5) (5), 677 - 680
    [Refereed]
    Scientific journal

  • Koji Amano, Satomi Okamura, Vickie Baracos, Naoharu Mori, Tatsuma Sakaguchi, Yu Uneno, Yusuke Hiratsuka, Jun Hamano, Tomofumi Miura, Hiroto Ishiki, Naosuke Yokomichi, Yutaka Hatano, Tatsuya Morita, Masanori Mori
    Objectives It is unknown to what extent the fluid retention (FR) status disrupts the detection of weight loss rate (WLR) in adult patients with advanced cancer. This study aimed to determine the association of FR status with WLR. Methods This study was a secondary analysis of a prospective cohort study. FR was evaluated as follows: oedema (0, no; 1, yes), pleural effusion (0, no; 1, yes but asymptomatic; 2, symptomatic) and ascites (0, no; 1, yes but asymptomatic; 2, symptomatic). Patients were divided into three groups according to their FR scores: no-FR (0), moderate-FR (1–2) and high-FR (3–5). Multiple regression analysis was performed. Results Four hundred and twenty patients were categorised: no-FR group (n=164), moderate-FR group (n=158) and high-FR group (n=98). The prevalence of oedema, pleural effusion and ascites was 63.9%, 27.8% and 36.7% in the moderate-FR group, and 93.9%, 61.3% and 82.6% in high-FR group. The means of WLR were 9.2, 8.4 and 3.8 in the groups. The high-FR group and the FR score of 5 were correlated with WLR (estimate −4.71, 95% CI −7.84 to –1.58; estimate −10.29, 95% CI −17.84 to –2.74). Conclusions The coexistence of FR was significantly correlated with WLR.
    BMJ, Feb. 2024, BMJ Supportive & Palliative Care, 14(e2) (e2), e1732 - e1737
    [Refereed]
    Scientific journal

  • Ryota Matsui, Masano Sagawa, Akihiko Sano, Makoto Sakai, Shin-Ichiro Hiraoka, Isao Tabei, Takayuki Imai, Hideo Matsumoto, Seiji Onogawa, Norihiro Sonoi, Shigeyuki Nagata, Ryo Ogawa, Shigeki Wakiyama, Yasuhiro Miyazaki, Koshi Kumagai, Rie Tsutsumi, Takehiro Okabayashi, Yu Uneno, Naoki Higashibeppu, Joji Kotani
    OBJECTIVE: To clarify whether perioperative immunonutrition is effective in adult patients with or without malnutrition undergoing elective surgery for head and neck or gastrointestinal (GI) cancers. BACKGROUND: It is important to avoid postoperative complications in patients with cancer as they can compromise clinical outcomes. There is no consensus on the efficacy of perioperative immunonutrition in patients with or without malnutrition undergoing head and neck or GI cancer surgery. METHODS: We searched MEDLINE (PubMed), MEDLINE (OVID), EMBASE, Cochrane Central Register of Controlled Trials, Web of Science Core Selection, and Emcare from 1981-2022 using search terms related to immunonutrition and head and neck or GI cancer. We included randomized controlled trials. Intervention was defined as immunonutritional therapy including arginine, n-3 omega fatty acids, or glutamine during the perioperative period. The control was defined as standard nutritional therapy. The primary outcomes were total postoperative and infectious complications, defined as events with a Clavien-Dindo classification grade ≥ II that occurred within 30 days after surgery. RESULTS: Of the 4825 patients from 48 included studies, 19 had upper GI cancer, nine lower, and eight mixed, while 12 had head and neck cancers. Immunonutrition reduced the total postoperative complications (relative risk ratio:0.78; 95% confidence interval:0.66, 0.93; certainty of evidence: high) and infectious complications (relative risk ratio:0.71; 95% confidence interval:0.61, 0.82; certainty of evidence: high) compared with standard nutritional therapy. CONCLUSIONS: Nutritional intervention with perioperative immunonutrition in patients with head and neck and gastrointestinal cancers significantly reduced total postoperative complications and infectious complications.
    Oct. 2023, Annals of surgery, English, International magazine
    [Refereed]
    Scientific journal

  • Yukiko Watanabe, Natsuki Kawashima, Yu Uneno, Soichiro Okamoto, Manabu Muto, Tatsuya Morita
    Corresponding, Mary Ann Liebert Inc, Sep. 2023, Palliative Medicine Reports, 4(1) (1), 257 - 263
    [Refereed]
    Scientific journal

  • Yu Uneno, Tatsuya Morita, Yukiko Watanabe, Soichiro Okamoto, Natsuki Kawashima, Manabu Muto
    Mary Ann Liebert Inc, May 2023, Journal of Palliative Medicine, 26(5) (5), 609 - 610
    [Refereed]
    Scientific journal

  • Lucie-May Golbourn, Rory Colman, Yu Uneno, Yasuhiro Kotera
    Abstract Nineteen million people were diagnosed with cancer, and almost ten million cancer deaths were recorded worldwide in 2020. The extent of cancer stigmatisation can be as prevalent as 80%. 24% of advanced cancer patients have been diagnosed with an anxiety or depressive disorder. The aim is to provide valuable plans of how it may be conceptually possible to form an intervention from a public health perspective. Preliminary observations identified a gap in research of a novel framework for cancer stigma. It is hoped this knowledge will build the foundations to develop an explanatory evidence-based theoretical model for improving the understanding, evaluation and planning of cancer stigma. Less than 6% of current studies are aimed at actually implementing interventions into practise. Using the Health Stigma and Discrimination Framework as an example, whilst drawing upon the independently existing theoretical work on stigma mechanisms and mental health intervention strategies, widening the field of exploration, through mixed method analysis concerning cancer stigma to address the barriers at person, provider, and societal levels, will expand upon the initial application of theories and suggest ways of countering the broader attitudes and beliefs. Guiding future evidence-based initiatives, designed to target and address the many levels at which, cancer stigma can derive. It holds the potential to map out public health directives and strategies, targeting such a multidimensional facet, intricately interwoven across a myriad of levels, being able to support a rationale as to the origins of stigma.
    Springer Science and Business Media LLC, Apr. 2023, SN Comprehensive Clinical Medicine, 5(1) (1)
    [Refereed]
    Scientific journal

  • Junko Ueshima, Ayano Nagano, Keisuke Maeda, Yoshiko Enomoto, Koshi Kumagai, Rie Tsutsumi, Naoki Higashibeppu, Yu Uneno, Joji Kotani
    BACKGROUND & AIMS: This systematic review aims to determine whether nutritional counseling by registered dietitians and/or nutritional specialists is recommended for adult patients with incurable advanced or recurrent cancer who are refractory to or intolerant of anticancer therapy. METHODS: This systematic review analyzed randomized controlled trials (RCTs) of nutritional counseling in cancer patients older than 18 years, primarily those with stage 4 cancer. Nutrition counseling was performed by registered dietitians and/or nutritional specialists using any method, including group sessions, telephone consultations, written materials, and web-based approaches. We searched the Medline (PubMed), Medline (OVID), EMBASE (OVID), CENTRAL, Emcare, and Web of Science Core Collection databases for articles published from 1981 to 2020. Two independent authors assessed the risk of bias used the Cochrane Risk of Bias 2 tool. Meta-analysis was performed for results and outcomes that allowed quantitative integration. This systematic review protocol was registered with the International Prospective Register of Systematic Reviews (ID: CRD42021288476) and registered in 2021. RESULTS: The search yielded 2376 studies, of which 7 assessed 924 patients with cancer aged 24-95 years. Our primary outcome of quality of life (QoL) was reported in 6 studies, 2 of which showed improvement with nutritional counseling. Our other primary outcome of physical symptoms was reported in two studies, one of which showed improvement with nutritional counseling. Quantitative integration of both QoL and physical symptoms was difficult. A meta-analysis of energy and protein intake and body weight was performed for secondary outcomes. Results showed that nutrition counseling increased energy and protein intake, but total certainty of evidence (CE) was low. Bodyweight was not improved by nutrition counseling. CONCLUSIONS: Nutrition counseling is shown to improve energy and protein intake in patients with incurable cancer. Although neither nutrient intake can be strongly recommended because of low CE, nutrition counseling is a noninvasive treatment strategy that should be introduced early for nutrition intervention for patients with cancer. This review did not find sufficient evidence for the effect of nutrition counseling on QoL, a patient-reported outcome. Overall, low-quality and limited evidence was identified regarding the impact of nutrition counseling for patients with cancer, and further research is needed.
    Elsevier BV, Feb. 2023, Clinical Nutrition, 42(2) (2), 227 - 234, English, International magazine
    [Refereed]
    Scientific journal

  • Yu Uneno, Yasuhiro Kotera, Daisuke Fujisawa, Yuki Kataoka, Kazuhiro Kosugi, Nanami Murata, Takaomi Kessoku, Akihiko Ozaki, Hirotomo Miyatake, Manabu Muto
    Introduction An easy-to-access and effective psychotherapy for bereaved informal caregivers has not been established. People with higher self-compassion status tend to have lower bereavement related grief, psychotherapy focused on self-compassion can be promising for this population. This study aimed to examine the feasibility of online self-compassion focused psychotherapy for bereaved informal caregivers. Method and analysis A total of 60 study participants will undergo an intervention programme comprising online sessions of 2 hours per week for five consecutive weeks and undertake postsession work. The intervention personnel will comprise psychologists who have received more than 10 hours of structured training. The primary endpoint will be assessed on the intervention completion rate, with secondary endpoints consisting of the Complicated Grief Questionnaire, Patient Health Questionnaire-9, Generalised Anxiety Disorder-7, Brief Resilience Scale and Self-Compassion Scale. Evaluations will be conducted preintervention, immediately after intervention, and 4 and 12 weeks after intervention. Ethics and dissemination This study has been reviewed and approved by the Ethics Committee of the Kyoto University Graduate School and Faculty of Medicine, Kyoto University Hospital, Japan (Approved ID: C1565). The results of this study will be disseminated through publication in a peer-reviewed journal and conference presentations. Trial registration number UMIN000048554.
    Lead, BMJ, Dec. 2022, BMJ Open, 12(12) (12), e067187 - e067187
    [Refereed]
    Scientific journal

  • Takaomi Kessoku, Yu Uneno, Yuka Urushibara-Miyachi, Kiyofumi Oya, Akihiko Kusakabe, Atsushi Nakajima, Noritoshi Kobayashi, Yasushi Ichikawa, Mitsunori Miyashita, Manabu Muto, Masanori Mori, Tatsuya Morita
    Abstract Background The appropriate delivery of death pronouncements potentially affects bereaved families’ wellbeing positively. Although younger physicians need to learn the competencies and entrustable professional activities (EPAs) to conduct death pronouncement independently, both of which have not been clarified. Therefore, this study aimed to develop a list of competencies and EPAs necessary for death pronouncement practice, which resident physicians need to acquire by the end of their residency training (postgraduate year 2). Methods An anonymous modified Delphi study was conducted with a panel of 31 experts. The experts were invited online from general wards in hospitals with resident physicians across Japan to participate in the study using the purposive and snowball sampling method. A non-anonymous web conference was held with three additional external evaluators to finalize the item list. The consensus criterion was defined as a mean response of at least 4 points on a 5-point Likert scale for each competency and EPA item and a rating of 4 or 5 points by at least 80% of the participants. Results Consensus was achieved, with consistently high levels of agreement across panel members, on 11 competencies and 9 EPA items. Additionally, a correspondence matrix table between competencies and EPAs was developed. Conclusions This study clarified the standardized educational outcomes as competencies in death pronouncement practice and the unit of professional practice of physicians who can perform this independently (EPAs), serving as a blueprint to aid the development of an educational model and evaluation method for clinical educational institutions and developers of medical school curriculums.
    Springer Science and Business Media LLC, Dec. 2022, BMC Medical Education, 22(1) (1)
    [Refereed]
    Scientific journal

  • Naosuke Yokomichi, Kengo Imai, Masaki Sakamoto, Masashi Horiki, Toshihiro Yamauchi, Satoru Miwa, Satoshi Inoue, Yu Uneno, Hidekazu Suzuki, Toru Wada, Yuri Ichikawa, Tatsuya Morita
    Abstract Background Malignant ascites often causes discomfort in advanced cancer patients. Paracentesis is the most common treatment modality, but it requires frequently repeated treatment. Cell-free and concentrated ascites reinfusion therapy (CART) may prolong the paracentesis interval, but controlled trials are lacking. We assessed the feasibility of a randomized controlled trial of CART vs. paracentesis alone for patients with refractory malignant ascites. Methods This study was an open-label, fast-track, randomized controlled, feasibility trial. Patients admitted to four designated cancer hospitals who received no further anticancer treatments were eligible. Patients were randomly assigned 1:1 to a CART arm or control (simple paracentesis) arm. The feasibility endpoint was the percentage of patients who completed the study intervention. Secondary endpoints included paracentesis-free survival, patient’s request on the questionnaire for paracentesis (PRO-paracentesis)-free survival (the period until the patients first reported that they would want paracentesis if indicated), and adverse events. Results We screened 953 patients for eligibility. Of 61 patients with refractory malignant ascites, 21 patients were determined as eligible. Finally, 20 patients consented and were allocated; 18 patients (90%, 95% CI: 68.3–98.8) completed the study intervention. All patients had an ECOG performance status of 3 or 4. The median drained ascites volume was 3,200 mL in the CART arm and 2,500 mL in the control arm. In the CART arm, the median reinfused albumin volume was 12.6 g. Median paracentesis-free survivals were 5 days (95% CI: 2–6) in the CART arm, and 6 days (3–9) in the control arm. Median PRO-paracentesis-free survivals were 4 days (2–5) and 5 days (1–9), respectively. A total of 73% of patients received paracentesis within 2 days from their first request for the next paracentesis. One patient in the CART arm developed Grade 1 fever. Conclusions A fast-track randomized controlled trial of CART for patients with malignant ascites is feasible. The efficacy and safety of CART should be assessed in future trials. PRO-paracentesis-free survival may be a complementary outcome measure with paracentesis-free survival in future trials. Trial registration Registered at University Hospital Medical Information Network Clinical Trial Registry as UMIN000031029. Registered on 28/01/2018.
    Springer Science and Business Media LLC, Dec. 2022, BMC Cancer, 22(1) (1)
    [Refereed]
    Scientific journal

  • Yu Uneno, Haruki Imura, Yosuke Makuuchi, Kentaro Tochitani, Norio Watanabe
    Wiley, Nov. 2022, Cochrane Database of Systematic Reviews, 2022(11) (11)
    [Refereed]
    Scientific journal

  • Tomoo Ikari, Yusuke Hiratsuka, Shao-Yi Cheng, Mitsunori Miyashita, Tatsuya Morita, Masanori Mori, Yu Uneno, Koji Amano, Yuko Uehara, Takashi Yamaguchi, Isseki Maeda, Akira Inoue
    Springer Science and Business Media LLC, Nov. 2022, Supportive Care in Cancer, 30(11) (11), 9577 - 9586
    [Refereed]
    Scientific journal

  • Soichiro Okamoto, Yu Uneno, Natsuki Kawashima, Shunsuke Oyamada, Yusuke Hiratsuka, Keita Tagami, Manabu Muto, Tatsuya Morita
    Corresponding, Mary Ann Liebert Inc, Oct. 2022, Palliative Medicine Reports, 3(1) (1), 255 - 263
    [Refereed]
    Scientific journal

  • Yu Uneno, Maki Iwai, Naoto Morikawa, Keita Tagami, Yoko Matsumoto, Junko Nozato, Takaomi Kessoku, Tatsunori Shimoi, Miyuki Yoshida, Aya Miyoshi, Ikuko Sugiyama, Kazuhiro Mantani, Mai Itagaki, Akemi Yamagishi, Tatsuya Morita, Akira Inoue, Manabu Muto
    BACKGROUND: Despite recommendations to deliver palliative care to cancer patients and their caregivers, their distress has not been alleviated satisfactorily. National health policies play a pivotal role in achieving a comprehensive range of quality palliative care delivery for the public. However, there is no standardised logic model to appraise the efficacy of these policies. This study aimed to develop a logic model of a national health policy to deliver cancer palliative care and to reach consensus towards specific policy proposals. METHODS: A draft version of the logic model and specific policy proposals were formulated by the research team and the internal expert panel, and the independent external expert panel evaluated the policy proposals based on the Delphi survey to reach consensus. RESULTS: The logic model was divided into three major conceptual categories: 'care-delivery at cancer hospitals', 'community care coordination', and 'social awareness of palliative care'. There were 18 and 45 major and minor policy proposals, which were categorised into four groups: requirement of government-designated cancer hospitals; financial support; Basic Plan to Promote Cancer Control Programs; and others. These policy proposals were independently evaluated by 64 external experts and the first to third Delphi round response rates were 96.9-98.4%. Finally, 47 policy proposals reached consensus. The priority of each proposal was evaluated within the four policy groups. CONCLUSIONS: A national health policy logic model was developed to accelerate the provision of cancer palliative care. Further research is warranted to verify the study design to investigate the efficacy of the logic model.
    Lead, Springer Science and Business Media LLC, Sep. 2022, International Journal of Clinical Oncology, 27(9) (9), 1529 - 1542, English, Domestic magazine
    [Refereed]
    Scientific journal

  • Hirotomo Miyatake, Akihiko Ozaki, Yasuhiro Kotera, Ryo Sakamoto, Divya Bhandari, Yu Uneno, Hiroyuki Beniya
    Wiley, Apr. 2022, Clinical Case Reports, 10(4) (4)
    [Refereed]
    Scientific journal

  • Yusuke Hiratsuka, Mitsunori Miyashita, Yu Uneno, Kiyohumi Oya, Soichiro Okamoto, Takaomi Kessoku, Hironori Mawatari, Shunsuke Oyamada, Junko Nozato, Keita Tagami, Akira Inoue
    Mary Ann Liebert Inc, Apr. 2022, Palliative Medicine Reports, 3(1) (1), 39 - 46
    [Refereed]
    Scientific journal

  • Kengo Imai, Tatsuya Morita, Naosuke Yokomichi, Masanori Mori, Akemi Shirado Naito, Toshihiro Yamauchi, Hiroaki Tsukuura, Yu Uneno, Satoru Tsuneto, Satoshi Inoue
    BACKGROUND: Palliative sedation is sometimes needed for refractory symptoms, and the Richmond Agitation-Sedation Scale (RASS) is one of the key measures. The primary aim of this study was to explore the association between RASS and degree of distress quantified by other measures: Item "symptom control" of Support Team Assessment Schedule (STAS, item 2), Discomfort Scale for Dementia of Alzheimer Type (Discomfort Scale), and Noncommunicative Patient's Pain Assessment Instrument (NOPPAIN), as well as a communication capacity measured by the Communication Capacity Scale (CCS), item 4. METHODS: This was a prospective observational study on terminally ill cancer patients with palliative sedation in a palliative care unit of a designated cancer hospital. Primarily responsible palliative care physicians rated RASS, Discomfort Scale, NOPPAIN, and CCS just before sedation and 1, 4, 24, and 48 hours after, and ward nurses rated STAS at the same time. Since the ward nurses evaluated STAS during palliative sedation, we regarded STAS as a standard of distress measure. RESULTS: A total of 249 assessments were performed for 55 patients. RASS was moderately to highly associated with symptom intensity measured by STAS, discomfort measured by the Discomfort Scale, and pain measured by NOPPAIN (r = 0.63 to 0.73). But communication capacity measured by CCS is not parallel with RASS and demonstrated a valley shape. In 82 assessments with an RASS score of -1 to -3, 11 patients (13%) had physical symptoms of STAS of 2 or more. CONCLUSIONS: RASS can roughly estimate physical distress in patients with palliative sedation, but a measure to more precisely quantify the symptom experience is needed.
    Mary Ann Liebert Inc, Apr. 2022, Palliative Medicine Reports, 3(1) (1), 47 - 54, English, International magazine
    [Refereed]
    Scientific journal

  • Takahiro Higashibata, Jun Hamano, Takayuki Hisanaga, Shingo Hagiwara, Miho Shimokawa, Ritsuko Yabuki, Naosuke Yokomichi, Junichi Shimoinaba, Rena Kamura, Mika Baba, Hiromi Funaki, Masanori Mori, Tatsuya Morita, Satoru Tsuneto, Yoshiyuki Kizawa, Satoshi Inoue, Kengo Imai, Hiroaki Tsukuura, Toshihiro Yamauchi, Akemi Shirado Naito, Isseki Maeda, Yu Uneno, Akira Yoshioka, Shuji Hiramoto, Ayako Kikuchi, Tetsuo Hori, Yosuke Matsuda, Hiroyuki Kohara, Keiko Tanaka, Kozue Suzuki, Tina Kamei, Yukari Azuma, Koji Amano, Teruaki Uno, Jiro Miyamoto, Hirofumi Katayama, Hideyuki Kashiwagi, Eri Matsumoto, Kiyofumi Oya, Takeya Yamaguchi, Tomonao Okamura, Hoshu Hashimoto, Shunsuke Kosugi, Nao Ikuta, Yaichiro Matsumoto, Takashi Ohmori, Takehiro Nakai, Takashi Ikee, Yuto Unoki, Kazuki Kitade, Shu Koito, Nanao Ishibashi, Masaya Ehara, Kosuke Kuwahara, Shohei Ueno, Shunsuke Nakashima, Yuta Ishiyama, Akihiro Sakashita, Ryo Matsunuma, Hana Takatsu, Takashi Yamaguchi, Satoko Ito, Toru Terabayashi, Jun Nakagawa, Tetsuya Yamagiwa, Akira Inoue, Takuhiro Yamaguchi, Mitsunori Miyashita, Saran Yoshida, Yusuke Hiratsuka, Keita Tagami, Hiroaki Watanabe, Takuya Odagiri, Tetsuya Ito, Masayuki Ikenaga, Keiji Shimizu, Akira Hayakawa, Tomohiro Nishi, Yasuhiro Shibata, Satoshi Miyake, Junko Nozato, Hiroto Ishiki, Tetsuji Iriyama, Keisuke Kaneishi, Tomofumi Miura, Yoshihisa Matsumoto, Kazuhiro Kosugi, Ayumi Okizaki, Yuki Sumazaki Watanabe, Yuko Uehara, Eriko Satomi, Kaoru Nishijima, Ryoichi Nakahori, Takeshi Hirohashi, Natsuki Kawashima, Takashi Kawaguchi, Megumi Uchida, Ko Sato, Yoichi Matsuda, Yutaka Hatano, Sayaka Maeda, Hiroyuki Otani
    Background: Patients with life-limiting illnesses frequently experience urinary difficulties, and urinary catheterization is one of the interventions for managing them. However, evidence supporting the effects of urinary catheters on the quality of death (QoD) is lacking in this population. Objectives: To investigate whether urinary catheterization affects QoD in patients with advanced cancer in palliative care units. Design: A secondary analysis of a multicenter, prospective cohort study. Setting/Subjects: The study enrolled consecutive patients with advanced cancer admitted to palliative care units in Japan between January and December 2017. Those who were not catheterized on admission and who died while in a palliative care unit were analyzed. Measurements: QoD was evaluated at death using the Good Death Scale (GDS). Results: Of 885 patients, 297 (33.6%) were catheterized during their palliative care unit stay. Females and patients with a long palliative care unit stay were more likely to be catheterized. In inverse probability-weighted propensity score analysis, patients with urinary catheterization during their palliative care unit stay had higher total GDS scores than those without catheterization (coefficient 0.410, 95% confidence interval 0.068-0.752). In subgroup analyses stratified by sex, age, and length of palliative care unit stay, urinary catheterization was associated with higher total GDS scores in patients younger than 65 years of age and those who died after a palliative care unit stay of 21 days or fewer. Conclusions: This study suggested that urinary catheterization during a palliative care unit stay may have a positive impact on overall QoD in patients with advanced cancer. This study was registered in the UMIN Clinical Trials Registry (UMIN000025457).
    Mary Ann Liebert Inc, Feb. 2022, Journal of Palliative Medicine, 25(2) (2), 205 - 212
    Scientific journal

  • Sayuri Yokota, Koji Amano, Shunsuke Oyamada, Hiroto Ishiki, Isseki Maeda, Tomofumi Miura, Yutaka Hatano, Yu Uneno, Tetsuo Hori, Yosuke Matsuda, Hiroyuki Kohara, Kozue Suzuki, Tatsuya Morita, Masanori Mori, Satoshi Inoue, Naosuke Yokomichi, Kengo Imai, Hiroaki Tsukuura, Toshihiro Yamauchi, Akemi Shirado Naito, Akira Yoshioka, Shuji Hiramoto, Ayako Kikuchi, Keiko Tanaka, Tina Kamei, Yukari Azuma, Teruaki Uno, Jiro Miyamoto, Hirofumi Katayama, Hideyuki Kashiwagi, Eri Matsumoto, Kiyofumi Oya, Takeya Yamaguchi, Tomonao Okamura, Hoshu Hashimoto, Shunsuke Kosugi, Nao Ikuta, Yaichiro Matsumoto, Takashi Ohmori, Takehiro Nakai, Takashi Ikee, Yuto Unoki, Kazuki Kitade, Shu Koito, Nanao Ishibashi, Masaya Ehara, Kosuke Kuwahara, Shohei Ueno, Shunsuke Nakashima, Yuta Ishiyama, Akihiro Sakashita, Ryo Matsunuma, Hana Takatsu, Takashi Yamaguchi, Satoko Ito, Toru Terabayashi, Jun Nakagawa, Tetsuya Yamagiwa, Akira Inoue, Takuhiro Yamaguchi, Mitsunori Miyashita, Saran Yoshida, Yusuke Hiratsuka, Keita Tagami, Hiroaki Watanabe, Takuya Odagiri, Tetsuya Ito, Masayuki Ikenaga, Keiji Shimizu, Akira Hayakawa, Rena Kamura, Takeru Okoshi, Tomohiro Nishi, Kazuhiro Kosugi, Yasuhiro Shibata, Takayuki Hisanaga, Takahiro Higashibata, Ritsuko Yabuki, Shingo Hagiwara, Miho Shimokawa, Satoshi Miyake, Junko Nozato, Specially Appointed, Tetsuji Iriyama, Keisuke Kaneishi, Mika Baba, Yoshihisa Matsumoto, Ayumi Okizaki, Yuki Sumazaki Watanabe, Yuko Uehara, Eriko Satomi, Kaoru Nishijima, Junichi Shimoinaba, Ryoichi Nakahori, Takeshi Hirohashi, Jun Hamano, Natsuki Kawashima, Takashi Kawaguchi, Megumi Uchida, Ko Sato, Yoichi Matsuda, Satoru Tsuneto, Sayaka Maeda, Yoshiyuki Kizawa, Hiroyuki Otani
    Elsevier BV, Feb. 2022, Clinical Nutrition Open Science, 41, 33 - 43
    [Refereed]
    Scientific journal

  • Hiraku Tsujimoto, Yuki Kataoka, Yukihito Sato, Masahiro Banno, Emi Tsujino-Tsujimoto, Yukiyoshi Sumi, Ryuichi Sada, Takashi Fujiwara, Yoichi Ohtake, Junji Kumasawa, Haruki Imura, Yoshinobu Matsuda, Ryuhei So, Tomoko Kagawa, Takashi Yoshioka, Yu Uneno, Hiroyuki Nagano, Mai Akazawa, Takunori Hozumi, Yasushi Tsujimoto
    Abstract Background Research engagement contributes to the improvement of patient care. A systematic review is a suitable first scholarly activity because it entails summarization of publicly available data and usually requires neither rigorous ethical review nor research funding. Methods This study aimed to develop a model workshop for healthcare staff to acquire skills in creating systematic review protocols based on their own clinical questions at teaching hospitals. We used an action research method to create a model workshop at four hospitals in Japan from April 2015 to March 2017. To improve the program, we solicited reflections using participant questionnaires for each lecture and examined the quality of homework submitted by participants after each lecture. We administered a revised final version of the workshop at five hospitals from April 2016 to March 2017. We evaluated the participants’ scholarly productivity related to these workshops. The observation period was a minimum of 2 years following the workshops. Results Most participants had never developed a formal clinical research protocol and voluntarily participated in the workshop. The action research was developed and implemented at nine teaching hospitals in Japan, including one university hospital. The study developed a model nine-step workshop curriculum: 1) Research question development, 2) Search strategy development, 3) Search strategy brush-up, 4) Exclusion and inclusion criteria development, 5) Risk of bias assessment planning, 6) Meta-analysis planning, 7) Subgroup and sensitivity analysis planning, 8) Planning the presentation of results, and 9) Presentation protocols. A total of 233 participants, including medical doctors and other health professionals, produced 414 research questions. Seventy-nine participants (34%) completed the workshop, and 47 review teams accomplished systematic review protocols. The participants published 13 peer-reviewed articles as a result of the workshop. Conclusions We developed a structured scholarly productive model workshop for healthcare staff working at hospitals. We found healthcare staff with clinical subspecialties were able to develop an unexpectedly high number of research questions through this workshop. Medical teachers at hospitals with prior systematic review experience could teach how to develop systematic review protocols using this model. Further research is needed to increase the academic productivity of such workshops. Trial registration UMIN (https://www.umin.ac.jp/ctr/), UMIN000017107 (4/15/2015), UMIN000025580 (1/10/2017).
    Springer Science and Business Media LLC, Dec. 2021, BMC Medical Education, 21(1) (1)
    [Refereed]
    Scientific journal

  • Tomoo Ikari, Yusuke Hiratsuka, Takuhiro Yamaguchi, Masanori Mori, Yu Uneno, Tomohiko Taniyama, Yosuke Matsuda, Kiyofumi Oya, Koji Amano, Keita Tagami, Akira Inoue
    AME Publishing Company, Nov. 2021, Annals of Palliative Medicine, 10(11) (11), 11278 - 11287
    [Refereed]
    Scientific journal

  • Satoko Ito, Tatsuya Morita, Yu Uneno, Tomohiko Taniyama, Yosuke Matsuda, Hiroyuki Kohara, Isseki Maeda, Takeo Nakayama, Masanori Mori
    Wiley, Jun. 2021, Cancer Medicine
    [Refereed]
    Scientific journal

  • Tomoo Ikari, Yusuke Hiratsuka, Takuhiro Yamaguchi, Isseki Maeda, Masanori Mori, Yu Uneno, Tomohiko Taniyama, Yosuke Matsuda, Kiyofumi Oya, Keita Tagami, Akira Inoue
    Wiley, Feb. 2021, Cancer Medicine, 10(3) (3), 1018 - 1026
    [Refereed]
    Scientific journal

  • Y. Uneno, K. Sato, T. Morita, M. Nishimura, S. Ito, M. Mori, C. Shimizu, Y. Horie, M. Hirakawa, T. E. Nakajima, S. Tsuneto, M. Muto
    Abstract Background Palliative care (PC) is increasingly recognized as essential for oncology care, and several academic societies strongly recommend integrating oncology and palliative care (IOP) in daily practice. Similarly, the Japanese government encouraged the implementation of IOP through the Cancer Control Act of 2007; however, its detailed progress remains unclear. Therefore, this cross-sectional nationwide survey was conducted to investigate the current status and hospital executive physicians’ perception of IOP. Methods The questionnaire was developed based on IOP indicators with international consensus. It was distributed to executive physicians at all government-designated cancer hospitals (DCHs, n = 399) and matched non-DCHs (n = 478) in November 2017 and the results were compared. Results In total, 269 (67.4%) DCHs and 259 (54.2%) non-DCHs responded. The number of PC resources in DCHs was significantly higher than those in non-DCHs (e.g., full-time PC physicians and nurses, 52.8% vs. 14.0%, p < 0.001; availability of outpatient PC service ≥3 days per week, 47.6% vs. 20.7%, p < 0.001). Routine symptom screening was more frequently performed in DCHs than in non-DCHs (65.1% vs. 34.7%, p < 0.001). Automatic trigger for PC referral availability was limited (e.g., referral using time trigger, 14.9% vs. 15.3%, p = 0.700). Education and research opportunities were seriously limited in both types of hospitals. Most executive physicians regarded IOP as beneficial for their patients (95.9% vs. 94.7%, p = 0.163) and were willing to facilitate an early referral to PC services (54.7% vs. 60.0%, p < 0.569); however, the majority faced challenges to increase the number of full-time PC staff, and < 30% were planning to increase the staff members. Conclusions This survey highlighted a considerable number of IOP indicators met, particularly in DCHs probably due to the government policy. Further efforts are needed to address the serious research/educational gaps.
    Springer Science and Business Media LLC, Dec. 2020, BMC Palliative Care, 19(1) (1)
    [Refereed]
    Scientific journal

  • Yu Uneno, Haruki Imura, Yosuke Makuuchi, Kentaro Tochitani, Norio Watanabe
    Wiley, May 2020, Cochrane Database of Systematic Reviews
    [Refereed]
    Scientific journal

  • Masanori Mori, Maiko Fujimori, Hiroto Ishiki, Tomohiro Nishi, Jun Hamano, Hiroyuki Otani, Yu Uneno, Akira Oba, Tatsuya Morita, Yosuke Uchitomi
    Abstract Introduction Although various phrases to communicate prognoses based on a certain concept have been proposed, no study has systematically investigated preferences of patients with cancer for actual phrases. We investigated whether phrases with a wider range and additional “hope for the best, and prepare for the worst” (hope/prepare) statement would be more preferable and explored variables associated with patients’ preferences. Materials and Methods In a cross-sectional survey, 412 outpatients with cancer self-assessed their preferences for 13 phrases conveying prognostic information (e.g., phrases with or without median, typical range, and/or best/worst cases, and those with or without a hope/prepare statement) on a 6-point scale (1 = not at all preferable; 6 = very preferable). We evaluated demographic data and the Coping Inventory for Stressful Situations and conducted multivariate regression analysis. Results Regarding phrases with various ranges, the one including the median, typical range, and best/worst cases was more preferable (mean ± SD, 3.8 ± 1.3; 95% confidence interval [CI], 3.6–3.9) than the one with the median and typical range (3.4 ± 1.2; 3.3–3.6) or the one with only the median (3.2 ± 1.3; 3.1–3.3). Concerning the hope/prepare statement, the phrase including the median, typical range, uncertainty, and hope/prepare statement was more preferable (3.8 ± 1.4; 3.7–3.9) than the one without the statement (3.5 ± 1.2; 3.4–3.6). In multivariate analyses, task-oriented coping was significantly correlated with preferences for phrases with explicit information. Conclusion Overall, phrases with a wider range and the hope/prepare statement were preferable to those without them. When patients with cancer ask about prognoses, especially those with task-oriented coping, clinicians may provide explicit information with a wider range and the hope/prepare statement. Implications for Practice Discussing prognoses with patients with advanced cancer is among the most important conversations for clinicians. In this cross-sectional survey to systematically investigate preferences of 412 patients with cancer for phrases conveying prognostic information, phrases with the median, typical range, and best/worst cases and those with the “hope for the best and prepare for the worst” (hope/prepare) statement were the most preferred. When patients with cancer ask about prognoses, clinicians may provide explicit information with a wider range and include the hope/prepare statement.
    Oxford University Press (OUP), Sep. 2019, The Oncologist, 24(9) (9), e943 - e952
    [Refereed]
    Scientific journal

  • Masanori Mori, Maiko Fujimori, Hiroto Ishiki, Tomohiro Nishi, Jun Hamano, Hiroyuki Otani, Yu Uneno, Akira Oba, Tatsuya Morita, Yosuke Uchitomi
    Elsevier BV, Jun. 2019, Journal of Pain and Symptom Management, 57(6) (6), 1121 - 1129
    [Refereed]
    Scientific journal

  • Yu Uneno, Manabu Muto, Tatsuya Morita
    Lead, Elsevier BV, Nov. 2018, The Lancet Oncology, 19(11) (11), e570 - e571
    [Refereed]
    Scientific journal

  • Yosuke Fujii, Yoshitaka Nishikawa, Motoo Nomura, Shin'ich Miyamoto, Yu Uneno, Takahiro Horimatsu, Manabu Muto
    Japanese Society of Internal Medicine, 2018, Internal Medicine, 57(8) (8), 1173 - 1176
    [Refereed]
    Scientific journal

  • Rihito Aizawa, Shigemi Matsumoto, Yu Uneno, Yoshitaka Nishikawa, Yoshinao Ozaki, Yukiko Mori, Masashi Kanai, Yuichi Ishida, Katsuyuki Sakanaka, Masahiro Hiraoka, Manabu Muto
    Oxford University Press (OUP), Sep. 2017, Japanese Journal of Clinical Oncology, 47(9) (9), 885 - 888
    [Refereed]
    Scientific journal

  • Yu Uneno, Kei Taneishi, Masashi Kanai, Kazuya Okamoto, Yosuke Yamamoto, Akira Yoshioka, Shuji Hiramoto, Akira Nozaki, Yoshitaka Nishikawa, Daisuke Yamaguchi, Teruko Tomono, Masahiko Nakatsui, Mika Baba, Tatsuya Morita, Shigemi Matsumoto, Tomohiro Kuroda, Yasushi Okuno, Manabu Muto
    Lead, Public Library of Science (PLoS), Aug. 2017, PLOS ONE, 12(8) (8), e0183291 - e0183291
    [Refereed]
    Scientific journal

  • Yoshitaka Nishikawa, Masashi Kanai, Maiko Narahara, Akiko Tamon, J. B. Brown, Kei Taneishi, Masahiko Nakatsui, Kazuya Okamoto, Yu Uneno, Daisuke Yamaguchi, Teruko Tomono, Yukiko Mori, Shigemi Matsumoto, Yasushi Okuno, Manabu Muto
    Springer Science and Business Media LLC, Apr. 2017, International Journal of Clinical Oncology, 22(2) (2), 269 - 273
    [Refereed]
    Scientific journal

  • Yu Uneno, Akira Yokoyama, Yoshitaka Nishikawa, Taro Funakoshi, Yoshinao Ozaki, Ikuo Aoyama, Kiichiro Baba, Daisuke Yamaguchi, Shuko Morita, Yukiko Mori, Masashi Kanai, Hisanori Kinoshita, Takeshi Inoue, Nobukatsu Sawamoto, Riki Matsumoto, Shigemi Matsumoto, Manabu Muto
    Lead, Japanese Society of Internal Medicine, 2016, Internal Medicine, 55(18) (18), 2605 - 2609
    [Refereed]
    Scientific journal

■ MISC
  • がん悪液質治療の新展開 -GDF-15を標的とした新規治療と免疫チェックポイント阻害-
    釆野優, 内藤立暁
    Lead, Jul. 2026, 腫瘍内科, 38(1) (1), 92 - 97, Japanese
    [Invited]

  • 【予後の対話の現在地-何を伝え,どう支えるか】(第VI章)予後の対話について思うこと 緩和ケアチームにおける予後対話と予後を見据えた減薬(de-prescribing)
    中川 夏樹, 釆野 優
    (株)青海社, Jun. 2026, 緩和ケア, 36(6月増刊) (6月増刊), 162 - 165, Japanese

  • Nagashima Ayaka, Tagami Keita, Odagiri Takuya, Uneno Yu
    Objective: We investigated the patterns of care transitions and the association between the number of care transitions and the achievement of a good death among terminal cancer patients. Methods: We conducted a self-administered questionnaire survey for the bereaved family members of cancer patients. The achievement of a good death was assessed using Good Death Inventory (GDI). Results: Of the 1789 bereaved family members who responded, we analyzed the 654 who had experienced care transitions. Following the completion of cancer treatment, 55.6% of patients were initially transferred to a hospital or ward other than a palliative care unit (PCU), 24.3% to a PCU, and 20.2% to their home or another care setting. Notably, 82% of patients initially transferred to a PCU died there, suggesting that the initial transfer destination may influence the place of death. No significant differences in GDI scores were observed among groups with one, two, or three or more care transitions. Conclusion: The number of care transitions in terminal cancer patients was not significantly associated with the achievement of a good death. Factors such as the complexity of transitions, concordance with patient preferences, and continuity of care should be considered to support the achievement of a good death in patients with terminal cancer who experience multiple care transitions.
    Japanese Society for Palliative Medicine, 2026, Palliative Care Research, 21(3) (3), 135 - 143, Japanese

  • 森田達也の落としてはいけないKey Article【第61回】遠隔臨床試験の緩和ケア研究での可能性-オンライングリーフケア介入試験の経験から
    釆野優, 森田達也
    2025, 緩和ケア, 35(5) (5)

  • Adaptation of a Death Pronouncement Training Program for Medical Students Across Facilities in Japan
    TANAKA Kosuke, TANAKA Kosuke, 釆野優, 飯嶋哲也, 結束貴臣, 結束貴臣
    2025, 医学教育, 56(Supplement) (Supplement)

  • 「セルフコンパッションに焦点を当てたオンライングループ心理療法の実施可能性試験」における成功の秘訣
    釆野優
    2025, Palliative Care Research (Web), 20(Supplement) (Supplement)

  • Year in Review「がん悪液質Up-to-Date2025」
    釆野優
    2025, 日本がんサポーティブケア学会学術集会プログラム・抄録集(Web), 10th

  • ePROと電子カルテ連携によるがん症状モニタリングの有用性と課題(RegiPRO研究:医療スタッフに対する利用後アンケート結果)
    堀江良樹, 宮路天平, 川口崇, 兼安貴子, 長島文夫, 土井綾子, 釆野優, 小倉孝氏, 山口拓洋, 中島貴子
    2025, 日本がんサポーティブケア学会学術集会プログラム・抄録集(Web), 10th

  • 釆野 優, 森田 達也
    (株)南山堂, Jan. 2025, 治療, 107(2) (2), 243 - 249, Japanese

  • 「現実的な」早期緩和ケアは「診断時から全員に関わる」早期緩和ケアと比較して非劣性である
    釆野 優, 森田 達也
    Lead, Jan. 2025, Evidence Update 2025 治療, 107(1) (1), 99 - 105
    [Invited]

  • 「早期からの緩和ケア」は、「診断時に緩和ケアチームが全員に関わること」ではなくてよいーTemel 2010研究をより現実的にした検証試験
    釆野優, 森田達也
    Lead, Nov. 2024, 緩和ケア, 34(6) (6), 516 - 523, Japanese
    [Invited]

  • がん緩和・支持療法&サイコオンコロジーUPto-DATE 気持ちのつらさガイドライン
    藤澤 大介, 藤澤 大介, 藤森 麻衣子, 吉川 栄省, 浅海 くるみ, 阿部 晃子, 荒井 幸子, 五十嵐 友里, 市倉 加奈子, 今井 晶子, 釆野 優, 大谷 弘行, 岡島 美朗, 岡村 優子, 茅野 綾子, 小早川 誠, 佐藤 温, 竹内 恵美, 田村 法子, 馬場 知子, 久村 和穂, 松本 禎久, 樅野 香苗, 柳井 優子, 奥山 徹, 稲垣 正俊, 貞廣 良一
    (NPO)日本肺癌学会, Oct. 2024, 肺癌, 64(5) (5), 342 - 342, Japanese

  • 「がんと診断された時からの緩和ケア」をいかに現場に広めるか 国が推進する「がんと診断された時からの緩和ケア」における根拠に基づく政策の立案と評価
    釆野 優
    (NPO)日本緩和医療学会, Jun. 2024, Palliative Care Research, 19(Suppl.) (Suppl.), S.24 - S.24, Japanese

  • 複合的介入の臨床試験におけるプロセス評価とはなにか?
    釆野 優
    (NPO)日本緩和医療学会, Jun. 2024, Palliative Care Research, 19(Suppl.) (Suppl.), S.42 - S.42, Japanese

  • 緩和ケア・サイコオンコロジーの卒前卒後教育 医師・医学生を対象とした緩和ケア・サイコオンコロジー教育
    釆野 優
    (NPO)日本緩和医療学会, Jun. 2024, Palliative Care Research, 19(Suppl.) (Suppl.), S.163 - S.163, Japanese

  • 緩和医療専門医・指導医のためのFaculty Developmentプログラムの確立
    釆野 優
    (NPO)日本緩和医療学会, Jun. 2024, Palliative Care Research, 19(Suppl.) (Suppl.), S.202 - S.202, Japanese

  • 死別を経験した人を対象としたセルフコンパッションに焦点を当てたオンライン心理療法に関する実施可能性試験 the COMPACT feasibility trial
    釆野 優, 小寺 康博, 菊池 亨子, 山田 美紗子, 杉谷 麻里, 寺戸 沙織, 前原 寛子, 坂本 結里, 管生 聖子, 谷 晴加, 清水 亜紀子, 久保 陽子, 藤澤 大介, 武藤 学
    (NPO)日本緩和医療学会, Jun. 2024, Palliative Care Research, 19(Suppl.) (Suppl.), S.289 - S.290, Japanese

  • 我が国における進行がん患者における早期緩和ケアの希望時期と内容について インターネットによる質問紙調査
    佐野 仁哉, 小田切 拓也, 田上 恵太, 釆野 優, 武藤 学, 武藤 学
    (NPO)日本緩和医療学会, Jun. 2024, Palliative Care Research, 19(Suppl.) (Suppl.), S.322 - S.323, Japanese

  • 誰一人取り残さないがん対策における格差のモニタリングと要因解明に資する研究 医療・共生分野(緩和ケア)における格差指標の検討に関する研究
    釆野優
    2024, 誰一人取り残さないがん対策における格差のモニタリングと要因解明に資する研究 令和5年度 総括・分担研究報告書(Web)

  • 複合的介入の開発と実施可能性試験
    結束貴臣, 結束貴臣, 結束貴臣, 田中幸介, 田中幸介, 東端孝博, 岸野恵, ネフ由紀子, 中島淳, 釆野優
    2024, 日本がんサポーティブケア学会学術集会プログラム・抄録集(CD-ROM), 9th

  • 複合的介入のランダム化比較試験:早期からの専門的緩和ケア介入試験の経験もふまえて
    松本禎久, 伊藤奈央, 大日方裕紀, 竹之内沙弥香, 釆野優
    2024, 日本がんサポーティブケア学会学術集会プログラム・抄録集(CD-ROM), 9th

  • 死別を経験した人を対象としたセルフコンパッションに焦点を当てたオンライン心理療法に関する実施可能性試験:the COMPACT feasibility trial
    釆野優, 小寺康博, 菊池亨子, 山田美紗子, 杉谷麻里, 寺戸沙織, 前原寛子, 坂本結里, 管生聖子, 谷晴加, 清水亜紀子, 久保陽子, 藤澤大介, 武藤学
    (NPO)日本緩和医療学会, 2024, 日本サイコオンコロジー学会総会(Web), 37th(Suppl.) (Suppl.), S.289 - S.290, Japanese

  • 国が推進する「がんと診断された時からの緩和ケア」における根拠に基づく政策の立案と評価
    釆野優
    (NPO)日本緩和医療学会, 2024, 日本サイコオンコロジー学会総会(Web), 37th(Suppl.) (Suppl.), S.24 - S.24, Japanese

  • 我が国における進行がん患者における早期緩和ケアの希望時期と内容について:インターネットによる質問紙調査
    佐野仁哉, 小田切拓也, 田上恵太, 田上恵太, 釆野優, 武藤学
    (NPO)日本緩和医療学会, 2024, 日本サイコオンコロジー学会総会(Web), 37th(Suppl.) (Suppl.), S.322 - S.323, Japanese

  • 緩和医療専門医・指導医のためのFaculty Developmentプログラムの確立
    釆野優
    (NPO)日本緩和医療学会, 2024, 日本サイコオンコロジー学会総会(Web), 37th(Suppl.) (Suppl.), S.202 - S.202, Japanese

  • 医師・医学生を対象とした緩和ケア・サイコオンコロジー教育
    釆野優
    (NPO)日本緩和医療学会, 2024, 日本サイコオンコロジー学会総会(Web), 37th(Suppl.) (Suppl.), S.163 - S.163, Japanese

  • 複合的介入の臨床試験におけるプロセス評価とはなにか?
    釆野優
    (NPO)日本緩和医療学会, 2024, 日本サイコオンコロジー学会総会(Web), 37th(Suppl.) (Suppl.), S.42 - S.42, Japanese

  • Complex intervention: Medical Research Council guidance.
    釆野優, 結束貴臣, 松本禎久, 石木寛人, 全田貞幹
    Lead, (有)科学評論社, Jan. 2024, 月刊腫瘍内科, 33(1) (1), 97 - 102, Japanese
    [Invited]

  • 複合的介入(Complex Intervention)と実装科学
    釆野優
    Lead, (株)青海社, Jul. 2023, 緩和ケア, 33(4) (4), 357 - 357, Japanese
    [Invited]

  • Development of an EHR and Smartphone-linked Adverse Reaction Monitoring System for Cancer Treatment Patients
    松本繁巳, 釆野優, 福山啓太, 杉山治, 江口佳那, 古島秀樹, 海野猛, 武藤学
    (一社)日本医療情報学会, Jun. 2023, 日本医療情報学会春季学術大会プログラム・抄録集, 27回, 195 - 196, Japanese

  • 緩和ケア普及啓発の地域展開-行政・拠点病院・地域社会の取り組みを活かす- 施策としての緩和ケア普及啓発の立案・評価手法をどうデザインするか?
    釆野 優
    (NPO)日本緩和医療学会, Jun. 2023, Palliative Care Research, 18(Suppl.) (Suppl.), S82 - S82, Japanese

  • 緩和ケアにマインドフルネスとコンパッションをどう活かすか? 大切な人を亡くした人々を対象としたコンパッションに焦点を当てたオンライン心理療法 実施可能性試験
    釆野 優
    (NPO)日本緩和医療学会, Jun. 2023, Palliative Care Research, 18(Suppl.) (Suppl.), S97 - S97, Japanese

  • 座学・ビデオ・ロールプレイを用いた看取りの学生教育に、事前動画学習を用いて教員の対面指導時間を短縮した際の困難感の改善効果を比較検討した研究
    田中 幸介, 竹田 雄馬, 平塚 裕介, 釆野 優, 大屋 清文, 岡本 宗一郎, 松本 衣里, 山代 亜紀子, 野里 洵子, 田上 恵太, 馬渡 弘典, 中島 淳, 市川 靖史, 森 雅紀, 森田 達也, 結束 貴臣
    (NPO)日本緩和医療学会, Jun. 2023, Palliative Care Research, 18(Suppl.) (Suppl.), S459 - S459, Japanese

  • 「がん患者のための代謝・栄養管理ガイドライン」の出版と今後の展望 作成法「がん患者のための代謝・栄養管理ガイドライン」の作成手順について
    釆野 優, 日本臨床栄養代謝学会がん患者のための代謝・栄養管理ガイドラインガイドライン委員会
    (一社)日本栄養治療学会, 2023, 学会誌JSPEN, 5(Suppl.1) (Suppl.1), 105 - 105, Japanese

  • 「がん患者のための代謝・栄養管理ガイドライン」の出版と今後の展望 CQ2,SR報告「がんと診断された患者さんに積極的栄養介入をすることは推奨されるか?」
    松本 英男, 小野川 靖二, 園井 教裕, 佐川 まさの, 脇山 茂樹, 小川 了, 宮崎 安弘, 永田 茂行, 岡林 雄大, 田妻 進, 二村 明彦, 東別府 直紀, 釆野 優, 小谷 穣治
    (一社)日本栄養治療学会, 2023, 学会誌JSPEN, 5(Suppl.1) (Suppl.1), 112 - 112, Japanese

  • 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究「現場や地域の実情に即したがん治療と並行する緩和ケア」の実装戦略の開発
    島津太一, 釆野優, 西村真由美, 宮崎貴久子, 中山健夫
    2023, 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 令和4年度 総括・分担研究報告書(Web)

  • 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 治療期における「現場や地域の実情に即したがん治療と並行する緩和ケア」の実装に関する研究
    中島貴子, 釆野優
    2023, 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 令和4年度 総括・分担研究報告書(Web)

  • 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 治療途中における「現場や地域の実情に即したがん治療と並行する緩和ケア」の実装に関する研究
    堀江良樹, 結束貴臣, 片岡裕貴, 釆野優
    2023, 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 令和4年度 総括・分担研究報告書(Web)

  • 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究「現場や地域の実情に即したがん治療と並行する緩和ケア」の均てん化を進めるための方策の確立
    井上彰, 森川直人, 田上恵太, 野里洵子, 結束貴臣, 岩井万喜, 松本陽子, 釆野優
    2023, 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 令和4年度 総括・分担研究報告書(Web)

  • 「実装を視野に入れたがん患者の精神心理的な支援に関する診療ガイドラインの開発研究」がん患者の気持ちのつらさガイドライン
    藤澤大介, 奥山徹, 内富庸介, 藤森麻衣子, 島津太一, 稲垣正俊, 貞廣良一, 吉川栄省, 浅海くるみ, 阿部晃子, 阿部晃子, 荒井幸子, 五十嵐友里, 市倉加奈子, 今井晶子, 釆野優, 大谷弘行, 大谷弘行, 岡島美朗, 岡村優子, 茅野綾子, 倉田明子, 小早川誠, 佐藤温, 竹内恵美, 田村法子, 馬場知子, 久村和穂, 松本禎久, 樅野香苗, 柳井優子
    2023, 実装を視野に入れたがん患者の精神心理的な支援に関する診療ガイドラインの開発研究 令和4年度 総括・分担研究報告書(Web)

  • がん患者・家族への精神・心理的支援のための複合的介入(Complex Intervention)とは何か?
    釆野優
    2023, 日本サイコオンコロジー学会総会(Web), 36th

  • 「がん患者のための代謝・栄養管理ガイドライン」の出版と今後の展望 作成法「がん患者のための代謝・栄養管理ガイドライン」の作成手順について
    釆野 優, 日本臨床栄養代謝学会がん患者のための代謝・栄養管理ガイドラインガイドライン委員会
    (一社)日本栄養治療学会, 2023, 学会誌JSPEN, 5(Suppl.1) (Suppl.1), 105 - 105, Japanese

  • 「がん患者のための代謝・栄養管理ガイドライン」の出版と今後の展望 CQ2,SR報告「がんと診断された患者さんに積極的栄養介入をすることは推奨されるか?」
    松本 英男, 小野川 靖二, 園井 教裕, 佐川 まさの, 脇山 茂樹, 小川 了, 宮崎 安弘, 永田 茂行, 岡林 雄大, 田妻 進, 二村 明彦, 東別府 直紀, 釆野 優, 小谷 穣治
    (一社)日本栄養治療学会, 2023, 学会誌JSPEN, 5(Suppl.1) (Suppl.1), 112 - 112, Japanese

  • ACPを軸とした緩和ケアのシームレス化 コロナ禍の教訓から得られた「望ましいACP・シームレスな緩和ケア」を支える地域の在り方
    釆野 優
    (NPO)日本緩和医療学会, Oct. 2022, Palliative Care Research, 17(Suppl._Kansai) (Suppl._Kansai), S563 - S563, Japanese

  • 早期からの緩和ケア:日本発のエビデンス、次に何をするべきか これまでの早期緩和ケアのエビデンス 臨床実装に向けた課題の整理
    釆野 優
    (NPO)日本緩和医療学会, Jul. 2022, Palliative Care Research, 17(Suppl.) (Suppl.), S.108 - S.108, Japanese

  • 精神・心理系ガイドラインからみるエビデンスUp to Date がん患者における気持ちのつらさガイドライン
    藤澤 大介, 藤森 麻衣子, 吉川 栄省, 浅海 くるみ, 阿部 晃子, 荒井 幸子, 五十嵐 友里, 市倉 加奈子, 今井 晶子, 釆野 優, 大谷 弘行, 岡島 美朗, 岡村 優子, 茅野 綾子, 小早川 誠, 佐藤 温, 竹内 恵美, 田村 法子, 馬場 知子, 久村 和穂, 松本 禎久, 樅野 香苗, 柳井 優子, 奥山 徹, 稲垣 正俊, 貞廣 良一
    (NPO)日本緩和医療学会, Jul. 2022, Palliative Care Research, 17(Suppl.) (Suppl.), S.125 - S.125, Japanese

  • 座学・ビデオ・ロールプレイを用いた看取りの学生教育に対する困難感の改善効果の検討
    田中 幸介, 結束 貴臣, 平塚 裕介, 釆野 優, 大屋 清文, 岡本 宗一郎, 松本 衣里, 山代 亜紀子, 野里 洵子, 田上 恵太, 馬渡 弘典, 日下部 明彦, 中島 淳, 市川 靖史, 森 雅紀, 森田 達也
    (NPO)日本緩和医療学会, Jul. 2022, Palliative Care Research, 17(Suppl.) (Suppl.), S.181 - S.181, Japanese

  • Yoshiki Horie, Tempei Miyaji, Takashi Kawaguchi, Takako Kaneyasu, Fumio Nagashima, Ayako Doi, Yu Uneno, Takashi Ogura, Takuhiro Yamaguchi, Takako Nakajima
    Jul. 2022, ANNALS OF ONCOLOGY, 33, S504 - S504, English
    [Refereed]
    Summary international conference

  • 早期からの緩和ケア:日本発のエビデンス、次に何をするべきか これまでの早期緩和ケアのエビデンス 臨床実装に向けた課題の整理
    釆野 優
    Lead, (NPO)日本緩和医療学会, Jul. 2022, Palliative Care Research, 17(Suppl.) (Suppl.), S.108 - S.108, Japanese

  • 精神・心理系ガイドラインからみるエビデンスUp to Date がん患者における気持ちのつらさガイドライン
    藤澤 大介, 藤森 麻衣子, 吉川 栄省, 浅海 くるみ, 阿部 晃子, 荒井 幸子, 五十嵐 友里, 市倉 加奈子, 今井 晶子, 釆野 優, 大谷 弘行, 岡島 美朗, 岡村 優子, 茅野 綾子, 小早川 誠, 佐藤 温, 竹内 恵美, 田村 法子, 馬場 知子, 久村 和穂, 松本 禎久, 樅野 香苗, 柳井 優子, 奥山 徹, 稲垣 正俊, 貞廣 良一
    (NPO)日本緩和医療学会, Jul. 2022, Palliative Care Research, 17(Suppl.) (Suppl.), S.125 - S.125, Japanese

  • 医師のPRO調査票とePROに対する認識と日常診療への導入に関する調査
    宮路天平, 川口崇, 堀江良樹, 土井綾子, 小倉孝氏, 兼安貴子, 釆野優, 長島文夫, 下妻晃二郎, 下妻晃二郎, 山口拓洋, 中島貴子
    2022, 日本がんサポーティブケア学会学術集会プログラム・抄録集, 7th (Web)

  • Assessing the implementation of electronic Patient Reported Outcome (ePRO) system in real world oncology practice
    釆野優, 松本繁己, 杉山治, 福山啓太, 武藤学
    2022, 日本臨床腫瘍学会学術集会(CD-ROM), 19th

  • 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究「現場や地域の実情に即したがん治療と並行する緩和ケア」の均てん化を進めるための方策の確立
    井上彰, 森川直人, 田上恵太, 野里洵子, 結束貴臣, 岩井万喜, 松本陽子, 釆野優
    2022, 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 令和3年度 総括・分担研究報告書(Web)

  • 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 治療途中における「現場や地域の実情に即したがん治療と並行する緩和ケア」の実装に関する研究
    堀江良樹, 結束貴臣, 片岡裕貴, 釆野優
    2022, 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 令和3年度 総括・分担研究報告書(Web)

  • 実装を視野に入れたがん患者の精神心理的な支援に関する診療ガイドラインの開発研究 がん患者の気持ちのつらさガイドライン
    藤澤大介, 奥山徹, 内富庸介, 藤森麻衣子, 島津太一, 稲垣正俊, 貞廣良一, 吉川栄省, 浅海くるみ, 阿部晃子, 荒井幸子, 五十嵐友里, 市倉加奈子, 今井晶子, 釆野優, 大谷弘行, 大谷弘行, 岡島美朗, 岡村優子, 茅野綾子, 倉田明子, 小早川誠, 佐藤温, 竹内恵美, 田村法子, 馬場知子, 久村和穂, 松本禎久, 樅野香苗, 柳井優子
    2022, 実装を視野に入れたがん患者の精神心理的な支援に関する診療ガイドラインの開発研究 令和3年度 総括・分担研究報告書(Web)

  • 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究「現場や地域の実情に即したがん治療と並行する緩和ケア」の実装戦略の開発
    島津太一, 釆野優, 西村真由美, 宮崎貴久子, 中山健夫
    2022, 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 令和3年度 総括・分担研究報告書(Web)

  • 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 治療期における「現場や地域の実情に即したがん治療と並行する緩和ケア」の実装に関する研究
    中島貴子, 釆野優
    2022, 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 令和3年度 総括・分担研究報告書(Web)

  • 進行がん患者の気持ちのつらさに早期からの緩和ケアは推奨されるか
    阿部晃子, 阿部晃子, 松本禎久, 釆野優
    2022, 日本サイコオンコロジー学会総会(Web), 35th

  • 「がん患者のための代謝・栄養管理ガイドライン」における作成プロセス
    釆野 優
    (一社)日本臨床栄養代謝学会, 2022, 学会誌JSPEN, 4(Suppl.1) (Suppl.1), 42 - 42, Japanese

  • Updated version of comparison between World Health Organization and Japanese Society for Palliative Medicine on cancer pain management guidelines.
    釆野優
    Lead, (有)科学評論社, Dec. 2021, 月刊腫瘍内科, 28(6) (6), 662 - 667, Japanese
    [Invited]

  • Hisashi Suyama, Hiroshi Sunada, Yu Uneno, Yoshiki Horie, Akemi Naito, Shunsuke Oyamada, Junko Nozato, Yasuyuki Kojima, Masanori Mori, Takako Nakajima, Chikako Shimizu, Tatsuya Morita, Satoru Tsuneto, Manabu Muto
    Jul. 2021, ANNALS OF ONCOLOGY, 32, S347 - S347, English
    [Refereed]
    Summary international conference

  • 「お看取り」の教育を考える 終末期ケア・死亡診断時の医療従事者の立ち居振る舞いに関する教育活動・研究の今後の展望
    釆野 優, 大屋 清文, 岡本 宗一郎, 川島 夏希, 結束 貴臣, 平塚 裕介, 田上 恵太
    (NPO)日本緩和医療学会, Jun. 2021, Palliative Care Research, 16(Suppl.) (Suppl.), S166 - S166, Japanese

  • 研修医が終末期ケアに関わる前向きさに関連する因子の探索 横断的全国質問紙調査
    川島 夏希, 釆野 優, 岡本 宗一郎, 平塚 裕介, 大屋 清文, 小杉 和博, 野里 洵子, 田上 恵太, 馬渡 弘典, 山代 亜紀子, 森田 達也
    (NPO)日本緩和医療学会, Jun. 2021, Palliative Care Research, 16(Suppl.) (Suppl.), S409 - S409, Japanese

  • 「お看取り」の教育を考える 研修医が終末期ケアに関わる前向きさに関連する因子の探索
    川島 夏希, 釆野 優, 岡本 宗一郎, 馬渡 弘典, 山代 亜紀子, 森田 達也
    (NPO)日本緩和医療学会, Jun. 2021, Palliative Care Research, 16(Suppl.) (Suppl.), S162 - S162, Japanese
    [Refereed]

  • 「お看取り」の教育を考える 死亡診断時の医師の立ち居振る舞いに関するコンピテンシーとEntrustable professional activityリストの確立
    結束 貴臣, 釆野 優, 大屋 清文, 宮地 由佳, 日下部 明彦, 小林 規俊, 中島 淳, 市川 靖史, 宮下 光令, 森 雅紀, 森田 達也
    (NPO)日本緩和医療学会, Jun. 2021, Palliative Care Research, 16(Suppl.) (Suppl.), S164 - S164, Japanese
    [Refereed]

  • 「お看取り」の教育を考える 終末期ケア・死亡診断時の医療従事者の立ち居振る舞いに関する教育活動・研究の今後の展望
    釆野 優, 大屋 清文, 岡本 宗一郎, 川島 夏希, 結束 貴臣, 平塚 裕介, 田上 恵太
    Lead, (NPO)日本緩和医療学会, Jun. 2021, Palliative Care Research, 16(Suppl.) (Suppl.), S166 - S166, Japanese
    [Refereed]

  • 悪性腹水に対する腹水濾過濃縮再静注法のランダム化比較試験の実施可能性と今後の展望
    横道 直佑, 今井 堅吾, 山内 敏宏, 三輪 聖, 井上 聡, 坂本 雅樹, 堀木 優志, 釆野 優, 和田 透, 鈴木 秀和, 市川 友理, 森田 達也
    (NPO)日本緩和医療学会, Jun. 2021, Palliative Care Research, 16(Suppl.) (Suppl.), S256 - S256, Japanese
    [Refereed]

  • 研修医が終末期ケアに関わる前向きさに関連する因子の探索 横断的全国質問紙調査
    川島 夏希, 釆野 優, 岡本 宗一郎, 平塚 裕介, 大屋 清文, 小杉 和博, 野里 洵子, 田上 恵太, 馬渡 弘典, 山代 亜紀子, 森田 達也
    (NPO)日本緩和医療学会, Jun. 2021, Palliative Care Research, 16(Suppl.) (Suppl.), S409 - S409, Japanese
    [Refereed]

  • 死亡診断時の医師の立ち居振る舞いに関するコンピテンシーおよびEntrustable professional activityの確立
    結束 貴臣, 釆野 優, 大屋 清文, 宮地 由佳, 日下部 明彦, 中島 淳, 市川 靖史, 宮下 光令, 森 雅紀, 森田 達也
    (NPO)日本緩和医療学会, Jun. 2021, Palliative Care Research, 16(Suppl.) (Suppl.), S409 - S409, Japanese
    [Refereed]

  • 研修医が直面する終末期ケアに携わる困難感は何か?何が有効か? 全国質問紙調査
    岡本 宗一郎, 釆野 優, 川島 夏希, 小山田 隼佑, 平塚 裕介, 田上 恵太, 森田 達也
    (NPO)日本緩和医療学会, Jun. 2021, Palliative Care Research, 16(Suppl.) (Suppl.), S410 - S410, Japanese
    [Refereed]

  • Richmond Agitation-Sedation Scale (RASS)は苦痛の評価尺度として適切か? 苦痛緩和のための鎮静を受けるがん患者におけるRASSと苦痛の強さとの関連性
    今井 堅吾, 森田 達也, 森 雅紀, 横道 直佑, 内藤 明美, 山内 敏宏, 十九浦 宏明, 釆野 優, 井上 聡
    (NPO)日本緩和医療学会, Jun. 2021, Palliative Care Research, 16(Suppl.) (Suppl.), S431 - S431, Japanese
    [Refereed]

  • 緩和ケア用Richmond Agitation-Sedation Scale(RASS)日本語版の信頼性・妥当性の検証
    今井 堅吾, 森田 達也, 森 雅紀, 横道 直佑, 内藤 明美, 山内 敏宏, 十九浦 宏明, 釆野 優, 井上 聡
    (NPO)日本緩和医療学会, Jun. 2021, Palliative Care Research, 16(Suppl.) (Suppl.), S432 - S432, Japanese
    [Refereed]

  • 悪性腹水に対する腹水濾過濃縮再静注法のランダム化比較試験の実施可能性試験
    横道 直佑, 今井 堅吾, 坂本 雅樹, 堀木 優志, 山内 敏宏, 三輪 聖, 井上 聡, 釆野 優, 鈴木 秀和, 和田 透, 市川 友理, 森田 達也
    (一社)日本外科学会, Apr. 2021, 日本外科学会定期学術集会抄録集, 121回, SF - 8, Japanese
    [Refereed]

  • Guideline in progress-がん患者さんの気持ちのつらさガイドライン
    藤澤大介, 藤森麻衣子, 浅海くるみ, 阿部晃子, 荒井幸子, 市倉加奈子, 釆野優, 岡島美朗, 岡村優子, 小早川誠, 竹内恵美, 馬場知子, 久村和穂, 松本禎久, 村上好恵, 樅野香苗, 柳井優子, 吉川栄省, 奥山徹
    2021, 日本サイコオンコロジー学会総会プログラム・抄録集, 34th (Web)

  • 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究「現場や地域の実情に即したがん治療と並行する緩和ケア」の均てん化を進めるための方策の確立
    井上彰, 森川直人, 田上恵太, 野里洵子, 結束貴臣, 岩井万喜, 松本陽子, 釆野優
    2021, 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 令和2年度 総括・分担研究報告書(Web)

  • 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究「現場や地域の実情に即したがん治療と並行する緩和ケア」の実装戦略の開発
    島津太一, 釆野優
    2021, 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 令和2年度 総括・分担研究報告書(Web)

  • 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 治療途中における「現場や地域の実情に即したがん治療と並行する緩和ケア」の実装に関する研究
    堀江良樹, 結束貴臣, 片岡裕貴, 釆野優
    2021, 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 令和2年度 総括・分担研究報告書(Web)

  • 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 治療期における「現場や地域の実情に即したがん治療と並行する緩和ケア」の実装に関する研究
    中島貴子, 釆野優, 西村真由美, 宮崎貴久子, 中山健夫
    2021, 現場や地域の実情に即したがん治療と併行する緩和ケアの実装の推進に関する研究 令和2年度 総括・分担研究報告書(Web)

  • 森田達也の落としてはいけないKey Article(論文)(第35回)緩和ケア×実装科学 : 現場で動くプログラムを想定して研究するパラダイム
    森田 達也, 釆野 優
    青海社, Jan. 2021, 緩和ケア, 31(1) (1), 70 - 75, Japanese

  • Integration of Oncology and Palliative Careの展望 「がんと診断されたときからの緩和ケア」の推進に関わる厚生労働行政への提言の策定
    釆野 優, 堀江 良樹, 森田 達也, 内藤 明美, 小山田 隼佑, 陶山 久司, 小島 康幸, 野里 洵子, 森 雅紀, 中島 貴子, 清水 千佳子, 恒藤 暁, 武藤 学
    Lead, (NPO)日本緩和医療学会, Aug. 2020, Palliative Care Research, 15(Suppl.) (Suppl.), S96 - S96, Japanese
    [Refereed]

  • Integration of Oncology and Palliative Careの展望 がん診断時からの緩和ケアを提供するための患者のアンメットニーズに関する研究
    内藤 明美, 釆野 優, 森田 達也, 堀江 良樹, 小山田 隼佑, 野里 洵子, 小島 康幸, 陶山 久司, 森 雅紀, 中島 貴子, 清水 千佳子, 恒藤 暁, 武藤 学
    (NPO)日本緩和医療学会, Aug. 2020, Palliative Care Research, 15(Suppl.) (Suppl.), S97 - S97, Japanese
    [Refereed]

  • 医療コミュニケーション:テクニックを超えてスキルとして学習する 看取り時の医師の立ち振る舞いに関する、シミュレーションを中心とした教育プログラムについて
    大屋 清文, 釆野 優, 岡本 宗一郎, 平塚 裕介, 小杉 和博, 田上 恵太, 馬渡 弘典, 野里 洵子, 森 雅紀, 奥山 慎一郎, 森田 達也
    (NPO)日本緩和医療学会, Aug. 2020, Palliative Care Research, 15(Suppl.) (Suppl.), S142 - S142, Japanese
    [Refereed]

  • 調節型鎮静プロトコルと持続的深い鎮静プロトコルの効果と安全性に関する前向き観察研究
    今井 堅吾, 森田 達也, 森 雅紀, 横道 直佑, 川口 崇, 山内 敏宏, 十九浦 宏明, 内藤 明美, 釆野 優, 井上 聡
    (NPO)日本緩和医療学会, Aug. 2020, Palliative Care Research, 15(Suppl.) (Suppl.), S209 - S209, Japanese
    [Refereed]

  • 緩和ケアを志す医師の多様化する課題に沿った、キャリア支援を探索する
    野里 洵子, 田上 恵太, 釆野 優, 山代 亜紀子, 馬渡 弘典, 松本 衣里, 森 雅紀, 森田 達也, 三宅 智
    (NPO)日本緩和医療学会, Aug. 2020, Palliative Care Research, 15(Suppl.) (Suppl.), S1184 - S1184, Japanese
    [Refereed]

  • がんと診断された時からの緩和ケアの推進に関する研究 診断時からの緩和ケアの促進・阻害因子に関する研究
    清水千佳子, 森雅紀, 釆野優
    2020, がんと診断された時からの緩和ケアの推進に関する研究 令和元年度 総括・分担研究報告書(Web)

  • のぞいてみよう! 国際学会最前線(vol.18)Integration of Oncology and Palliative Careのこれから
    釆野 優
    Lead, 青海社, Sep. 2019, 緩和ケア, 29(5) (5), 463 - 465, Japanese

  • 持続的鎮静開始後の短期間での死亡に関する検討
    今井 堅吾, 森田 達也, 森 雅紀, 横道 直佑, 山内 敏宏, 釆野 優, 井上 聡
    (NPO)日本緩和医療学会, Jun. 2019, Palliative Care Research, 14(Suppl.) (Suppl.), S370 - S370, Japanese
    [Refereed]

  • 「オンコロジーと緩和医療の統合」と実装科学との接点
    釆野優
    2019, 日本がんサポーティブケア学会学術集会プログラム・抄録集, 4th

  • がんと診断された時からの緩和ケアの推進に関する研究 診断時からの緩和ケアの促進・阻害因子に関する研究
    清水千佳子, 森雅紀, 釆野優
    2019, がんと診断された時からの緩和ケアの推進に関する研究 平成30年度 総括・分担研究報告書(Web)

  • Yu Uneno, Mayumi Nishimura, Satoko Ito, Tatsuya Morita, Kazuki Sato, Masanori Mori, Chikako Shimizu, Yoshiki Horie, Mami Hirakawa, Takako Eguchi Nakajima, Satoru Tsuneto, Manabu Muto
    Lead, Dec. 2018, JOURNAL OF CLINICAL ONCOLOGY, 36(34) (34), English
    [Refereed]
    Summary international conference

  • 難治性悪性腹水に対するトリアムシノロンアセトニド腹腔内投与の効果と安全性の探索
    横道 直佑, 井上 聡, 今井 堅吾, 山内 敏宏, 釆野 優, 森 雅紀, 森田 達也
    (一財)日本消化器病学会, Oct. 2018, 日本消化器病学会雑誌, 115(臨増大会) (臨増大会), A791 - A791, Japanese
    [Refereed]

  • 難治性悪性腹水に対するトリアムシノロンアセトニド腹腔内投与の効果と安全性の探索
    横道 直佑, 今井 堅吾, 山内 敏宏, 十九浦 宏明, 釆野 優, 内藤 明美, 森 雅紀, 井上 聡
    (NPO)日本緩和医療学会, Jun. 2018, Palliative Care Research, 13(Suppl.) (Suppl.), S358 - S358, Japanese
    [Refereed]

  • 緩和ケアUpdate 2018 内科医が知っておきたい4領域のエビデンス
    大屋 清文, 釆野 優, 小杉 和博, 岡本 宗一郎, 岡村 知直, 森 雅紀
    (一社)米国内科学会日本支部, Jun. 2018, ACP(米国内科学会)日本支部年次総会プログラム集, 2018, 2 - 2, Japanese
    [Refereed]

  • がんと診断された時からの緩和ケアの推進に関する研究 診断時からの緩和ケアの促進・阻害因子に関する研究
    清水千佳子, 森雅紀, 釆野優
    2018, がんと診断された時からの緩和ケアの推進に関する研究 平成29年度 総括・分担研究報告書(Web)

  • 【早期からの緩和ケアコトハジメ】「早期緩和ケア」「オンコロジーと緩和ケアの連携」「がんと診断されたときからの緩和ケア」のちがい
    釆野 優, 森 雅紀, 森田 達也, 武藤 学
    (株)青海社, Jan. 2018, 緩和ケア, 28(1) (1), 005 - 010, Japanese

  • 抗がん剤治療中止を伝えられる際の説明に対するがん患者の意向
    藤森 麻衣子, 森 正紀, 石木 寛人, 浜野 淳, 大谷 弘行, 釆野 優, 大庭 章, 西 智弘, 森田 達也, 内富 庸介
    (一社)日本サイコオンコロジー学会・日本臨床死生学会, Oct. 2017, 日本サイコオンコロジー学会総会・日本臨床死生学会総会合同大会プログラム・抄録集, 30回・23回, 208 - 208, Japanese
    [Refereed]

  • Patient preferred explanations in discussing cessation of chemotherapy
    Maiko Fujimori, Masanori Mori, Hiroto Ishiki, Jun Hamano, Tomohiro Nishi, Hiroyuki Otani, Yu Uneno, Akira Oba, Tatsuya Morita, Yosuke Uchitomi
    Aug. 2017, PSYCHO-ONCOLOGY, 26, 115 - 116, English
    [Refereed]
    Summary international conference

  • 曽根 久智, 荘子 万能, 釆野 優, 森本 隆之, 片岡 裕貴, 松本 謙太郎, 伊藤 俊之
    (株)羊土社, Jun. 2017, レジデントノート, 19(4) (4), 741 - 743, Japanese

  • 「予後2年」の望ましい伝え方:どのようながん患者がどのような台詞を好むか?
    森雅紀, 森雅紀, 藤森麻衣子, 西智弘, 石木寛人, 浜野淳, 大谷弘行, 釆野優, 森田達也, 内富庸介
    2017, 日本臨床腫瘍学会学術集会(CD-ROM), 15th

  • 食道癌取扱い規約第10版vs.第11版の予後予測能についての検討
    野村 基雄, 釆野 優, 石田 祐一, 坂中 克行, 角田 茂, 篠原 尚, 天沼 裕介, 尾崎 由直, 宮本 心一, 武藤 学
    (NPO)日本食道学会, Jul. 2016, 日本食道学会学術集会プログラム・抄録集, 70回, 211 - 211, Japanese
    [Refereed]

  • 菌血症併発Ipilimumab関連腸炎の一例
    野村基雄, 西川佳孝, 釆野優, 尾崎由直, 天沼裕介, 山田敦, 森由希子, 高忠之, 金井雅史, 松本繁巳, 武藤学
    2016, 日本臨床腫瘍学会学術集会(CD-ROM), 14th

  • 時系列リアルワールドデータを用いた進行がん患者予後予測モデルの構築
    釆野優, 種石慶, 金井雅史, 岡本和也, 岡本和也, 山本洋介, 吉岡亮, 野崎明, 松本繁巳, 奥野恭史, 奥野恭史, 武藤学
    2016, 日本臨床腫瘍学会学術集会(CD-ROM), 14th

  • A new approach to collecting biobank and bioinformatics data at Kyoto University Cancer Center
    Manabu Muto, Yu Uneno, Yoshitaka Nishikawa, Yukiko Mori, Masashi Kanai, Shigemi Mastumoto, Genta Kato, Tomohiro Kuroda, Satoshi Morita, Yasushi Okuno
    Nov. 2015, ANNALS OF ONCOLOGY, 26, 90 - 90, English
    [Refereed]
    Summary international conference

  • Establishment of a terminal prognosis prediction model by applying time series analysis to real-world data
    Yu Uneno, Kei Taneishi, Masashi Kanai, Akiko Tamon, Kazuya Okamoto, Yoshitaka Nishikawa, J. B. Brown, Shigemi Matsumoto, Yasushi Okuno, Manabu Muto
    Lead, Nov. 2015, ANNALS OF ONCOLOGY, 26, 99 - 99, English
    [Refereed]
    Summary international conference

  • 当院におけるレゴラフェニブの使用経験
    山口 大介, 森 由希子, 釆野 優, 西川 佳孝, 船越 太郎, 尾崎 由直, 青山 育雄, 堀松 高博, 野崎 明, 金井 雅史, 松本 繁巳, 武藤 学
    (一財)日本消化器病学会, Sep. 2015, 日本消化器病学会雑誌, 112(臨増大会) (臨増大会), A923 - A923, Japanese
    [Refereed]

  • 食道癌に対する化学放射線治療中にCMV食道炎を発症した1例
    釆野 優, 相澤 理人, 青山 育雄, 森 由希子, 山口 大介, 野崎 明, 尾崎 由直, 西川 佳孝, 松本 繁己, 武藤 学
    Lead, (一社)日本内科学会, Feb. 2015, 日本内科学会雑誌, 104(Suppl.) (Suppl.), 142 - 142, Japanese
    [Refereed]

  • 診断に苦慮したCalcifying Fibrous Tumorの1例
    西川 佳孝, 釆野 優, 尾崎 由直, 山口 大介, 野崎 明, 森 由希子, 金井 雅史, 松本 繁己, 武藤 学
    (一社)日本内科学会, Feb. 2015, 日本内科学会雑誌, 104(Suppl.) (Suppl.), 282 - 282, Japanese
    [Refereed]

  • 京大病院がんセンターにおけるバイオバンクとメディカルバイオインフォマティクスプロジェクト
    武藤学, 釆野優, 西川佳孝, 森由希子, 金井雅史, 松本繁巳, 加藤源太, 黒田知宏, 森田智視, 奥野恭史
    2015, 日本臨床腫瘍学会学術集会(CD-ROM), 13th

  • 時系列リアルワールドデータ解析による終末期予後予測モデルの確立
    釆野優, 種石慶, 金井雅史, 多門啓子, 岡本和也, 西川佳孝, BROWN J.B., 松本繁巳, 奥野恭史, 奥野恭史, 武藤学
    2015, 日本臨床腫瘍学会学術集会(CD-ROM), 13th

  • Yu Uneno, Tadayuki Kou, Masashi Kanai, Michio Yamamoto, Peng Xue, Yukiko Mori, Yasushi Kudo, Akira Kurita, Norimitsu Uza, Yuzo Kodama, Masanori Asada, Toshihiko Masui, Shujiro Yazumi, Shigemi Matsumoto, Kyoichi Takaori, Satoshi Morita, Manabu Muto, Tsutomu Chiba
    Lead, Jan. 2015, JOURNAL OF CLINICAL ONCOLOGY, 33(3) (3), English
    [Refereed]
    Summary international conference

  • 釆野 優
    Lead, (株)羊土社, Oct. 2014, レジデントノート, 16(10) (10), 1936 - 1940, Japanese

  • 左傍十二指腸ヘルニアに対し腹腔鏡補助下根治術を施行した一例
    釆野 優, 桂井 隆明, 前田 遥, 石田 恵梨, 米山 克二郎, 上田 剛士
    Lead, 洛和会ヘルスケアシステム, Mar. 2013, 洛和会ヘルスケア学会集録, 23回, 160 - 161, Japanese

  • 学生による「生徒会」設立における問題点
    西川 知宏, 釆野 優, 戸上 由貴, 道井 亮輔, 森村 美奈, 津村 圭, 廣橋 一裕
    (一社)日本医学教育学会, Jul. 2008, 医学教育, 39(Suppl.) (Suppl.), 130 - 130, Japanese

■ Books And Other Publications
  • 神経障害性疼痛薬物療法ガイドライン
    日本ペインクリニック学会, 日本ペインクリニック学会神経障害性疼痛薬物療法ガイドライン作成ワーキンググループ
    Others, 外部評価, 文光堂, Jun. 2026, Japanese, ISBN: 9784830628634

  • 膵癌診療ガイドライン = Clinical practice guidelines for pancreatic cancer
    日本膵臓学会膵癌診療ガイドライン改訂委員会
    Contributor, 金原出版, Jul. 2025, Japanese, ISBN: 9784307205009

  • サルコペニア・フレイルの予防・改善に関するデジタルヘルスのためのガイドライン
    Others, 外部評価, ライフサイエンス出版, Jun. 2025, ISBN: 4897754917

  • 死別と悲嘆の精神医学
    明智, 龍男, 浅井, 真理子, 坂口, 幸弘, 瀬藤, 乃理子, 松岡, 弘道
    Contributor, 南山堂, Apr. 2025, Japanese, ISBN: 9784525382612

  • がん患者における気持ちのつらさガイドライン 2024年版
    日本サイコオンコロジー学会, 日本がんサポーティブケア学会
    Contributor, 金原出版株式会社, Sep. 2024, ISBN: 9784307102094

  • がん患者診療のための栄養治療ガイドライン 2024年版 総論編
    日本栄養治療学会
    Editor, 統括班, 金原出版株式会社, Sep. 2024, ISBN: 9784307702478

  • 生活期におけるリハビリテーション・栄養・口腔管理の協働に関するケアガイドライン
    「生活期におけるリハビリテーション・栄養・口腔管理の協働に関するケアガイドラインおよびマニュアルの整備に資する研究」班厚生労働科学研究費補助金 (長寿科学政策研究事業), 厚生労働省
    Others, 外部評価, 医学書院, May 2024, Japanese, ISBN: 9784260055925

  • がん薬物療法に伴う末梢神経障害診療ガイドライン
    日本がんサポーティブケア学会
    金原出版, Jun. 2023, Japanese, ISBN: 9784307204712

  • がん支持医療テキストブック : サポーティブケアとサバイバーシップ
    日本がんサポーティブケア学会
    Contributor, 金原出版, Oct. 2022, Japanese, ISBN: 9784307204439

  • 膵癌診療ガイドライン
    日本膵臓学会膵癌診療ガイドライン改訂委員会
    Others, システマティックレビュー, 金原出版, Jul. 2022, Japanese, ISBN: 9784307204545

  • ひと目でわかる実装科学 = Implementation Science at a Glance : がん対策実践家のためのガイド
    Joint translation, 東京 : 保健医療福祉における普及と実装科学研究会(RADISH), Sep. 2021, Japanese, ISBN: 9784991188619

  • がん疼痛の薬物療法に関するガイドライン
    日本緩和医療学会ガイドライン統括委員会
    金原出版, Jul. 2020, Japanese, ISBN: 9784307102025

  • Palliative Care
    Contributor, Intech Open, Oct. 2019, ISBN: 9781789840766

  • 高齢者のがん薬物療法ガイドライン
    日本臨床腫瘍学会, 日本癌治療学会
    Others, システマティックレビュー, 南江堂, Jul. 2019, Japanese, ISBN: 9784524240135

  • Highlights on Several Underestimated Topics in Palliative Care
    Contributor, Intech Open, Oct. 2017, ISBN: 9789535135661

  • 膵癌診療ガイドライン
    日本膵臓学会膵癌診療ガイドライン改訂委員会
    Others, システマティックレビュー, 金原出版, Oct. 2016, Japanese, ISBN: 9784307203609

■ Affiliated Academic Society
  • 日本緩和医療学会
    Apr. 2014 - Present

  • 日本臨床代謝栄養学会

  • 日本内科学会

  • 日本サイコオンコロジー学会

  • 日本がんサポーティブケア学会

■ Research Themes
  • 心情認知学：ダイナミックなこころの機微を理解し寄り添う社会の創成
    上田 祥行
    日本学術振興会, 科学研究費助成事業, 学術変革領域研究(B), 京都大学, Apr. 2025 - Mar. 2028, Coinvestigator

  • 死別後悲嘆の心情理解
    釆野 優
    日本学術振興会, 科学研究費助成事業, 学術変革領域研究(B), 京都大学, Apr. 2025 - Mar. 2028, Principal investigator

  • 死別を経験した人を対象としたコンパッションに焦点を当てたオンライン心理療法の効果：待機対照ランダム化比較試験
    日本緩和医療学会 2023年度 緩和ケアに関する研究助成, Nov. 2023 - Oct. 2027, Principal investigator

  • がん悪液質における肝での蛋白合成低下機序の解明と治療標的の探索
    釆野 優
    日本学術振興会, 科学研究費助成事業, 若手研究, 京都大学, Apr. 2024 - Mar. 2027, Principal investigator

  • 誰一人取り残さないがん対策における格差のモニタリングと要因解明に資する研究
    伊藤 ゆり, 祖父江 友孝, 藤 也寸志, 鈴木 達也, 中谷 友樹, 片岡 葵, 澤田 典絵, 田中 宏和, 西岡 大輔, 福井 敬祐, 藤阪 保仁, 花房 真理子, 釆野 優, 本多 和典, 久村 和穂
    厚生労働省, 厚生労働科学研究費 がん対策総合研究事業, Apr. 2023 - Mar. 2026

  • がん患者の遺族を対象としたセルフコンパッションに焦点を当てた新規心理療法の開発：実施可能性試験
    日本緩和医療学会, 2021年度 緩和ケアに関する研究助成, Nov. 2021 - Oct. 2025, Principal investigator

  • 大切な人を亡くした人々を対象としたコンパッションに焦点を当てたオンライン心理療法の経験に関する研究
    笹川保健財団, 2023年度「笹川保健財団研究助成」, Apr. 2023 - Apr. 2024, Principal investigator

  • がん終末期患者における血中アミノ酸欠乏を標的とする新規治療法開発
    釆野 優
    日本学術振興会, 科学研究費助成事業 特別研究員奨励費, 特別研究員奨励費, 京都大学, 28 Apr. 2021 - 31 Mar. 2023
    本研究の目的は、進行がん終末期患者の血中アミノ酸欠乏の是正が蛋白合成を回復させ、生命予後を改善させるかを明らかにすることである。 そのために、【in vitro研究】① がん細胞における特定のアミノ酸異常消費の同定（がん細胞株による培地中のアミノ酸消費状況を分析）、②細胞内アミノ酸欠乏と蛋白合成能低下との因果関係の検討（アミノ酸欠乏状況における正常細胞での総合的な蛋白合成の分析と関連するカスケードの探索）、③細胞内アミノ酸欠乏の是正による蛋白合成能の改善効果の検討を行う（効果的なアミノ酸補充方法の探索）。【in vivo研究】④アミノ酸補充療法を立案し、マウス担癌モデルを用いて前臨床試験を行う。【臨床研究】⑤進行がん患者における臨床経過増悪と関連する特定のアミノ酸欠乏の同定を行う。①～⑤の結果を統合し、進行・再発性がん患者を対象としたProof of Concept試験の立案を目指す。 研究の進捗状況：①～④の基礎研究において、がん細胞を培養した培養液やマウスの血中アミノ酸濃度の経時的変化に関する検討では、包括的なアミノ酸濃度の動態変化が示唆された。一方で興味深いことに、動物実験では、我々の仮説と反して、一時的なアミノ酸濃度の上昇を同定した。今後、これらの背景にあるメカニズムをRNAシーケンス等で関連する遺伝子発現を同定する予定である。また、臨床研究では、本学におけるがん患者の血液試料を後方視的に検討し、基礎研究同様、経時的な血中アミノ酸濃度の変化が同定された。本研究に関する前向き観察研究の研究計画書が、本学における倫理審査で承認され、被験者の組み入れを順次行っていく予定である。

  • 現場や地域の実情に即したがん治療と並行する緩和ケアの実装の推進に関する研究
    厚生労働省, 厚生労働科学研究費補助金, Apr. 2020 - Mar. 2023, Coinvestigator not use grants

  • 死亡診断時の意志の立ち居振る舞いに関するコンピテンシー（能力：知識・技能・態度）の確立
    日本ホスピス･緩和ケア研究振興財団, 2020年度 ホスピス/緩和ケアに関する調査・研究助成, Apr. 2020 - Mar. 2021, Coinvestigator

  • 我が国の研修医が直面する緩和ケアに関する困難感の実態：横断的全国調査
    笹川記念保健協力財団, ホスピス緩和ケアに関する研究助成, Apr. 2019 - Mar. 2020, Principal investigator

  • がんと診断された時からの緩和ケアの推進に関する研究
    厚生労働省, 厚生労働科学研究費補助金, Apr. 2017 - Mar. 2020, Coinvestigator not use grants

  • 癌終末期患者における血中アミノ酸欠乏を標的とする新規治療法の開発
    公益財団法人 ホクト生物化学振興財団, 令和2年度研究奨励金給付事業, 2020, Principal investigator

  • A feasibility study of the use of Actigraphy to determine prognosis in patients with advanced cancer: The United Kingdom-Japan International Collaborative Study.
    Daiwa Foundation Small Grant 2016, Apr. 2017 - Jun. 2017, Principal investigator

  • Validation of a Novel Prognosis Prediction Model for Cancer Patients in European Population.
    ESMO 2016 Palliative Care Research Fellowship Award, Apr. 2017 - Jun. 2017, Principal investigator

■ Social Contribution Activities
  • 死別後悲嘆に対するオンライングループ心理療法研究 ～実臨床や地域社会への実装課題～
    京都大学医学部附属病院 緩和医療科
    Lecturer, 第3回Kyoto西京緩和ケアRevolutions 「地域で支える"グリーフケア"」, 10 May 2025

  • 緩和ケア普及のためのロジックモデル
    第16回北海道がん心身医療連携ネットワーク研究会・講演会
    Lecturer, 23 Nov. 2024

  • 「標準的な」がん治療との付き合い方
    京都大学医学部附属病院
    Lecturer, 第14回 患者・家族のためのがんセミナー, 18 Sep. 2024

  • 緩和ケアを患者・家族に届けるために医療現場が期待するイノベーション
    第67回 情報処理学会エンタテインメントコンピューティング研究会
    Lecturer, 16 Mar. 2023

■ Media Coverage
  • ESMO ASIA 2016 PRESS RELEASE: ROUTINE BLOOD TEST PREDICTS HOW LONG CANCER PATIENTS WILL SURVIVE
    ESMO Asia 2016 Congress, Dec. 2016, https://www.esmo.org/meeting-calendar/past-meetings/esmo-asia-2016-congress/News/routine-blood-test-predicts-how-long-cancer-patients-will-survive
    Internet

■ Others
  • 日本緩和医療学会 緩和医療指導医
    Apr. 2024 - Present

  • Diplomate, Specialty Board of Palliative Medicine, JSPM
    Apr. 2020 - Present

  • 日本内科学会 認定内科医
    Apr. 2015 - Present

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