SEARCH
Search Details
MANIWA YoshimasaGraduate School of Medicine / Faculty of Medical SciencesProfessor
Research activity information
■ Paper- ROS proto-oncogene 1 receptor tyrosine kinase (ROS1)-rearranged lung cancer is rare and comprises only 1% of lung adenocarcinoma cases. It has recently been reported to have good response to crizotinib, a tyrosine kinase inhibitor of anaplastic lymphoma kinase. Driver oncogene mutations with approved therapies seldom coexist with a high expression of Programmed death-ligand 1 (PD-L1). The present case report describes a rare case of ROS1 rearrangement with high-PD-L1-expressing occult lung adenocarcinoma. A 32-year-old woman presented with chest pain and a prolonged cough. Chest computed tomography (CT) revealed a 57×36-mm tumor in the mediastinum, with no tumors detected in other regions. Positron emission tomography (PET)-CT showed a strong fluorodeoxyglucose accumulation in the tumor (SUVmax 13.2). Mediastinal tumor resection was completely resected using a video-assisted thoracic surgery approach. Pathological examination showed the tumor cells were positive for thyroid transcription factor 1, Napsin-A, ROS1, and PD-L1 (tumor proportion score >99%). ROS1 rearrangement was confirmed by fluorescence in situ hybridization. The mediastinal tumor was diagnosed as mediastinal lymph node metastasis of ROS1-rearranged PD-L1 high-expression undifferentiated lung adenocarcinoma (pathological stage 3, TxN2M0). Two months after the operation, the CT scan showed multiple mediastinum lymph nodes metastases with rapid tumor growth. The patient achieved a complete response after three cycles of S-1 plus cisplatin with concurrent radiotherapy 60 Gy/30 Fr.Jan. 2019, Oncol Lett, 17(1) (1), 488 - 491, English, International magazine[Refereed]Scientific journal
- Dec. 2018, 胸部外科, 71(13) (13), 1077 - 1080, Japanese上大静脈の再建のための5-Frカテーテルによる一時的なバイパス[Refereed]Scientific journal
- 21歳男性。健診の胸部X線にて異常陰影を指摘され、胸部CTで上大静脈(SVC)浸潤を伴う8cm大の前縦隔腫瘍を認めたため、精査加療目的で当院へ紹介となった。診断と治療目的で外科切除を行ったところ、腫瘍は前縦隔に存在し、心膜、左腕頭静脈、SVCに浸潤していたため、心膜と左腕頭静脈を合併切除した。SVC浸潤に対しては人工血管置換が必要であり、術中5Fr細径チューブによる一時シャントを作成した。SVC遮断中はシャント間に取り付けられたシリンジを用手的にポンピングすることで静脈還流を補助し、循環動態の安定を得ることができた。病理組織学的には精上皮腫で、心膜、SVCの浸潤を認めたが、切除断端は陰性であった。術後はBEP療法を4コース施行した。術後1年経過現在、無再発生存中である。(株)南江堂, Dec. 2018, 胸部外科, 71(13号) (13号), 1077 - 1080, Japanese[Refereed]Scientific journal
- Dec. 2018, Gen Thorac Cardiovasc Surg, EnglishNatural history of bulla neogenesis for primary spontaneous pneumothorax: a propensity score analysis[Refereed]Scientific journal
- Background: Advances in the development of staplers for pulmonary vessels have contributed to safe and convenient procedures in thoracic surgery. However, adverse events (AEs) can occur during vascular stapling and cause fatal hemorrhage. We aimed to assess the risk level of using the vessel stapling procedure to reduce such AEs. Methods: First, an animal experiment using pig cardiopulmonary blocks was conducted. Pulmonary arteries were closed with staplers under stressful conditions such as lifting or twisting; vessel stump endurance was analyzed through different methods. Second, AEs associated with clinical stapler use for pulmonary vessels were retrospectively reviewed by studying clinical videos of 263 patients. Results: In the animal experiment, the pressure resistance was significantly lower in the twisted group than in the no strain group (no strain vs. lifting: P=0.2008, no strain vs. twisting: P=0.002, no strain vs. twisting and lifting: P<0.0001). Regarding clinical stapler use, 754 staplers were used against the vessels. AEs occurred in 9 cases, and 7 cases were suspected to be caused by vessel tension. Conclusions: The pulmonary vessel stapling causes stress due to twisting and lifting that decreased stump durability. Avoiding such stress when using stapler for vessels leads to a safer thoracic surgery.Dec. 2018, J Thorac Dis, 10(12) (12), 6466 - 6471, English, International magazine[Refereed]Scientific journal
- 40歳女性。3年前より歩行時、会話時に呼吸困難感を自覚し近医を受診、喘息を疑われステロイド吸入薬などの治療を受けたが、症状が徐々に増悪したため、精査加療目的で当院へ紹介となった。胸部CTでは声門直下の気管に著明な狭窄が認められた。気管支鏡検査結果および挿管歴などがないことから、本症例は特発性声門下狭窄症(ISS)と診断され、外科的治療として輪状軟骨を一部含め、3リング長の気管を管状切除した後、輪状軟骨と気管を吻合した。術後、呼吸困難感は著明に改善し、術後6ヵ月現在、再狭窄なく良好に経過している。(株)南江堂, Nov. 2018, 胸部外科, 71(12号) (12号), 1018 - 1021, Japanese[Refereed]Scientific journal
- Nov. 2018, 胸部外科, 71(12) (12), 1018 - 1021, Japanese特発性憩室狭窄を有する患者の成功した治療法[Refereed]Scientific journal
- Oct. 2018, 肺癌, 58(5号) (5号), 371, Japanese肺性肥大性骨関節症を合併したROS1融合遺伝子陽性肺癌の1例[Refereed]Scientific journal
- Oct. 2018, 肺癌, 58(6号) (6号), 562, Japanese当科における肺切除後の同側再切除症例の検討[Refereed]Scientific journal
- Oct. 2018, 肺癌, 58(6号) (6号), 656, Japanese当院における肺多形癌の臨床病理学的検討[Refereed]Scientific journal
- Oct. 2018, 肺癌, 58(6号) (6号), 564, Japanese診断に苦慮した肺動脈内進展型原発性肺癌の1切除例[Refereed]Scientific journal
- Oct. 2018, 肺癌, 58(6号) (6号), 613, Japanese術後乳糜胸、膿胸、左総頸動脈出血を来し、迅速な対応により制御し得た左肺尖部胸壁浸潤癌の切除例[Refereed]Scientific journal
- Oct. 2018, 肺癌, 58(6号) (6号), 501, Japanese左下葉合併切除が必要であった巨大後縦隔脂肪肉腫の1例[Refereed]Scientific journal
- Oct. 2018, 肺癌, 58(6号) (6号), 721, Japanese胸腺非定型カルチノイドの2手術例[Refereed]Scientific journal
- Oct. 2018, 肺癌, 58(6号) (6号), 740, Japanese気管支喘息を背景にもつ肺原発MALTリンパ腫に対し外科的切除を行った1例[Refereed]Scientific journal
- Oct. 2018, 肺癌, 58(5号) (5号), 379, Japaneseハイリスク症例に対する予防的気管支断端被覆についての検討[Refereed]Scientific journal
- Oct. 2018, 肺癌, 58(6号) (6号), 497, Japaneseアプローチに検討を要した巨大後縦隔脂肪肉腫の一例[Refereed]Scientific journal
- Sep. 2018, 日本レーザー医学会誌, 39(3号) (3号), 246, Japanese切除範囲の決定にAFIが有用であった気管分岐部切除を伴う左肺全摘術の1例[Refereed]Scientific journal
- Sep. 2018, 気管支学, 40(5号) (5号), 414, Japanese高田ら“食道亜全摘術後に生じた胃管気管瘻に対し、有茎肋間筋弁による気管修復術が有効であった1例”[Refereed]Scientific journal
- Sep. 2018, 胸部外科, 71(10) (10), 881 - 885, Japanese胸部手術における連続胸部ドレナージシステム[Refereed]Scientific journal
- Sep. 2018, 胸部外科, 71(10号) (10号), 881 - 885, Japanese【胸部外科を支えるテクノロジーup to date】呼吸器領域 呼吸器外科における持続吸引装置[Refereed]Scientific journal
- Jul. 2018, 医学教育, 49(Suppl.) (Suppl.), 236, Japanese初期臨床研修医を対象としたSOC(Sense of Coherence)によるレジリエンス測定とストレス対処能力自己評価[Refereed]Scientific journal
- Jul. 2018, 医学教育, 49(Suppl.) (Suppl.), 237, Japanese初期臨床研修における復職支援「Back-on-trackプログラム」の実践と課題[Refereed]Research society
- Malignant pleural mesothelioma (MPM) is a highly aggressive tumor with poor prognosis and closely related to exposure to asbestos. MPM is a heterogeneous tumor with three main histological subtypes, epithelioid, sarcomatoid, and biphasic types, among which sarcomatoid type shows the poorest prognosis. The Ror-family of receptor tyrosine kinases, Ror1 and Ror2, is expressed in various types of tumor cells at higher levels and affects their aggressiveness. However, it is currently unknown whether they are expressed in and involved in aggressiveness of MPM. Here, we show that Ror1 and Ror2 are expressed in clinical specimens and cell lines of MPM with different histological features. Studies using MPM cell lines indicate that expression of Ror2 is associated tightly with high invasiveness of MPM cells, whereas Ror1 can contribute to their invasion in the absence of Ror2. However, both Ror1 and Ror2 promote proliferation of MPM cells. We also show that promoted invasion and proliferation of MPM cells by Ror signaling can be mediated by the Rho-family of small GTPases, Rac1, and Cdc42. These findings elucidate the critical role of Ror signaling in promoting invasion and proliferation of MPM cells.Jul. 2018, Genes to cells : devoted to molecular & cellular mechanisms, 23(7) (7), 606 - 613, English, International magazine[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), V9 - 3, Japanese肺膿瘍部に対する広範なドレーン損傷による有瘻性膿胸に対し集学的治療が奏功した1例[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), P44 - 7, Japanese肺血管処理における自動縫合器の適正使用についての検討[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), P36 - 1, Japanese当院におけるびまん性肺疾患に対する胸腔鏡下肺生検の検討[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), P67 - 6, Japanese転移性肺腫瘍との鑑別に苦慮した肺芽腫の1例[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), O19 - 1, Japanese早期肺腺癌におけるPsf3(GINS3)の発現とUFTの有効性についての検討[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), V18 - 1, Japanese浸潤型胸腺腫の切除後の再発に対しreverse hockey stick incisionにて切除を行った1例[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), P91 - 3, Japanese術後横隔神経麻痺に対する胸腔鏡下横隔膜縫縮術の検討[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), P64 - 5, Japanese縦隔内異所性副甲状腺腫に対し縦隔腫瘍摘除術を行った2例[Refereed]Scientific journal
- Apr. 2018, 胸部外科, 71(4) (4), 265 - 269, Japanese集学的療法におけるビデオ支援胸部手術の役割[Refereed]Scientific journal
- Apr. 2018, 肺癌, 58(2号) (2号), 150 - 151, Japanese胸腺類基底細胞癌の1例[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), O13 - 4, Japanese胸腔鏡下手術における胸腔内高度癒着症例に対する当院での取り組み[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), V3 - 2, Japanese気管分岐部切除を伴う左肺全摘術にPCPSが有用であった1例[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), RO7 - 1, Japanese癌細胞株と3次元in vitroモデルを応用した癌浸潤における候補遺伝子の解明[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), P28 - 2, Japanese開窓術を要した難治性膿胸の治療戦略について[Refereed]Research society
- Apr. 2018, 胸部外科, 71(4号) (4号), 265 - 269, Japanese【肺癌の集学的治療の現況】手術と集学的治療 集学的治療における完全胸腔鏡下手術の役割[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), V6 - 5, JapaneseSVC再建が必要な縦隔腫瘍切除において簡便な一時シャントが有用であった1例[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), P71 - 8, JapaneseOccult縦隔リンパ節転移を生じたROS1融合遺伝子陽性PD-L1強陽性肺腺癌の切除例[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), RO7 - 2, JapaneseIL-6 signalの阻害は、肺癌幹細胞を標的にした新規治療法になりうるか[Refereed]Scientific journal
- Mar. 2018, 胸部外科, 71(3号) (3号), 179, Japaneseまい・てくにっく 胸腔鏡手術における葉間肺動脈露出のポイント[Refereed]Scientific journal
- Mar. 2018, Ann Thorac Surg, EnglishPleural Coating by 50% Glucose Solution Reduces Postoperative Recurrence of Spontaneous Pneumothorax[Refereed]Scientific journal
- Jan. 2018, 気管支学, 40(1号) (1号), 81, Japanese当院における自然気胸に対する単孔式胸腔鏡下手術の検討[Refereed]Scientific journal
- Dec. 2017, 肺癌, 57(7号) (7号), 892, Japanese嚢胞内に発生した胸腺原発類基底細胞癌の1例[Refereed]Scientific journal
- Dec. 2017, 肺癌, 57(7号) (7号), 894, Japanese安全な胸腔鏡下肺葉切除術・縦隔リンパ節郭清のために[Refereed]Scientific journal
- Nov. 2017, 日本呼吸器外科学会雑誌, 31(7) (7), 885 - 889, Japanese難治性出血を合併した外傷性肺嚢胞の1例Scientific journal
- Sep. 2017, 肺癌, 57(5) (5), 416, Japanese人工肺癌幹細胞を用いた、肺癌組織再構築と新規治療法開発の試みResearch society
- Sep. 2017, 肺癌, 57(5) (5), 429, Japanese診断的治療目的に手術した後縦隔神経節細胞腫の3例Research society
- Sep. 2017, 肺癌, 57(5) (5), 577, Japanese初発から15年の経過で肺転移を生じたgrade1髄膜腫の一例Research society
- Sep. 2017, 肺癌, 57(5) (5), 564, Japanese胸腺嚢胞に合併した胸腺癌の一切除例Research society
- Sep. 2017, 肺癌, 57(5) (5), 568, Japanese気管支原性嚢胞からの発生が疑われた平滑筋肉腫の一切除例Research society
- Sep. 2017, 肺癌, 57(5) (5), 409, Japanese気管支形成を伴う区域切除術を要した両側同時多発肺癌の手術例Research society
- Sep. 2017, 肺癌, 57(5) (5), 410, Japanese右S2区域切除術後9年目に完全胸腔鏡下completion lobectomyを行った1例Research society
- PRR11 immunoreactivity is a weak prognostic factor in non-mucinous invasive adenocarcinoma of the lung.INTRODUCTION: Proline-rich protein 11 (PRR11) functions in the progression of cell cycle, and silencing the PRR11 gene in lung cancer cells results in the inhibition of cellular proliferation, cell cycle progression, cell migration, invasion and colony formation. PRR11 may therefore be a therapeutic target in lung cancer. MATERIALS AND METHODS: Microarrays of surgical specimens of non-mucinous invasive adenocarcinoma of the lung, from 346 subjects that were not given preoperative therapy, were autoimmunostained with PRR11 and, except for trace and pseudo-positivity, assessed as "positive" at any proportion and intensity. RESULTS: PRR11 immunoreactivity demonstrated a tendency to associate with an aggressive phenotype (tumor size, vascular invasion, and adjuvant therapy) and some effect on overall survival (Hazard ratio 1.51). CONCLUSIONS: PRR11 may be a weak prognostic indicator of overall survival of patients with non-mucinous invasive adenocarcinoma of the lung.Sep. 2017, Pathologica, 109(3) (3), 133 - 139, English, International magazine[Refereed]Scientific journal
- Sep. 2017, Sci Rep, 7(1) (1), 12317, EnglishInterleukin-6 blockade attenuates lung cancer tissue construction integrated by cancer stem cells[Refereed]Scientific journal
- Purpose Recently, single-incision thoracoscopic surgery (SITS) has been recognized as a favorable treatment choice for primary spontaneous pneumothorax (PSP) compared with conventional three-port video-assisted thoracoscopic surgery (VATS). However, conventional SITS bullectomy often results in collisions with surgical devices. Therefore, we devised a method of SITS using a chest wall pulley for lung excision (PulLE) and modified PulLE (mPulLE) system, which substitutes threads to eliminate such collisions. We compared the mPulLE system with conventional procedures using propensity score matching (PSM) to adjust for patient backgrounds. Methods Using PSM, we evaluated the surgical results of 210 PSP patients who underwent VATS, including mPulLE (n=23) and three-port VATS (n=102), at our institution between January 2010 and August 2016. Results We selected 17 mPulLE cases and 17 three-port VATS. There were no marked differences between the groups in the patient backgrounds or surgical results. However, there was a significant difference between the mPulLE cases and the three-port VATS cases in the operative time (71.7 +/- 15.7 vs. 85.9 +/- 25.5 min, respectively, P=0.0388) and the number of autosutures used (3.6 +/- 1.2 vs. 4.5 +/- 1.2, respectively, P = 0.0178). Conclusion The surgical results of mPulLE in patients with PSP with multiple lesions were equivalent to those achieved with three-port VATS under the same conditions.SPRINGER, Sep. 2017, SURGERY TODAY, 47(9) (9), 1129 - 1134, English[Refereed]Scientific journal
- 南江堂, Jul. 2017, 胸部外科, 70(8号) (8号), 688 - 691, Japanese【胸部外科領域における合併症予防のための周術期管理】呼吸器領域 術後胸腔内出血 術中における予防と発生時の対応[Refereed]Scientific journal
- Objective: Radical resection for thoracic malignancies that invade the great vessels or heart structure is an uncommon, high-risk operation. To help surgeons determine therapeutic strategy, we reviewed the patient characteristics and outcomes of combined thoracic and cardiovascular surgery for thoracic malignancies. Methods: Surgical resections of lung cancer, mediastinal tumor and pulmonary artery sarcoma invading great vessels or heart structures were reviewed from the literature. Results: Pneumonectomy was often performed for lung cancer invading the aorta, superior vena cava, and left atrium. Complete resection (R0), no mediastinal lymph node metastasis and without using cardiopulmonary bypass led to a good prognosis. Induction therapy was often performed for complete resection. Regarding mediastinal tumors, thymic epithelial tumors or germ cell tumors occasionally invaded the great vessels or heart structures. For these malignancies, multimodality therapy was often performed, and complete resection could be one of the prognostic factors. The resection of primary pulmonary artery sarcoma (PPAS) is also a combined thoracic and cardiovascular surgery. The primary treatment for PPAS is surgical resection specifically, pulmonary endarterectomy and pneumonectomy, because PPAS has substantial resistance to chemotherapy or radiotherapy. The prognosis of PPAS is poor, but surgical resection has potential for long-term survival. Conclusion: Although these surgeries are uncommon and invasive for the patients, selecting appropriate patients, aggressive multimodality therapy, and performing combined thoracic and cardiovascular surgery can contribute to a good outcome.Springer Tokyo, Jul. 2017, General Thoracic and Cardiovascular Surgery, 65(7) (7), 365 - 373, English[Refereed]Scientific journal
- Jul. 2017, Ann Thorac Surg, 104(1) (1), 370, EnglishReply[Refereed]Scientific journal
- Jun. 2017, 肺癌, 57(3) (3), e252, Japanese縦隔原発骨外性骨肉腫の1例Scientific journal
- Jun. 2017, Cytometry Research, 27(Suppl) (Suppl), 36, JapaneseiPS細胞を巡る最新の動向と今後の研究展開 人工癌幹細胞と癌オルガノイドを用いた癌幹細胞研究Research society
- Apr. 2017, 日本呼吸器外科学会雑誌, 31(3) (3), O10 - 2, Japanese続発性気胸に対する手術症例の検討Research society
- Apr. 2017, 日本呼吸器外科学会雑誌, 31(3) (3), P71 - 4, Japanese術後横隔神経麻痺に対する横隔膜縫縮術の検討Research society
- Apr. 2017, 日本呼吸器外科学会雑誌, 31(3) (3), P103 - 6, Japanese血液透析患者に対する原発性肺癌手術症例の検討Research society
- Apr. 2017, 日本呼吸器外科学会雑誌, 31(3) (3), O14 - 6, Japanese胸腺腫に関連した新規疾患概念、抗PIT-1抗体症候群Research society
- Apr. 2017, 日本気管食道科学会会報, 68(2) (2), s20, Japanese気管分岐部切除を要した右肺全摘の1例Scientific journal
- Apr. 2017, 日本呼吸器外科学会雑誌, 31(3) (3), O19 - 3, Japanese完全鏡視下手術手技を用いた拡大手術についての検討Research society
- Apr. 2017, 日本呼吸器外科学会雑誌, 31(3) (3), 68 - 6, Japanese外科的切除によって著明な改善を認めた胸壁発生の腫瘍性低リン血症性骨軟化症の一例Scientific journal
- Apr. 2017, 日本呼吸器外科学会雑誌, 31(3) (3), 37 - 1, JapaneseVolume reductionにて症状が改善した縦隔原発骨外性骨肉腫の1例Scientific journal
- Mar. 2017, 日本整形外科学会雑誌, 91(2号) (2号), S607, Japanese骨・軟部悪性腫瘍における肺転移切除例の治療成績[Refereed]Scientific journal
- Background: Bullectomy using autosutures is the standard procedure in patients with primary spontaneous pneumothorax (PSP). However, postoperative bulla neogenesis (POBN) along the staple line is relatively common and promotes PSP recurrence. We have previously reported the relationship between POBN and resected lung weight (LW). However, recently published data indicate that young patients with PSP have a high postoperative recurrence rate. Therefore, we evaluated the relationship between POBN and LW in PSP patients, subdivided according to age. Methods: Between February 2011 and April 2016, 96 lung-resection sites in 67 patients who underwent bullectomy were evaluated. Patients were subdivided into two groups by age: Y group (< 25 years, 56 sites) and O group (>= 25 years, 40 sites). We used the inverse-probability of treatment weighted (IPTW) method to adjust for the heterogeneity in their backgrounds. POBN was diagnosed by computed tomography. Results: Cox regression analysis for the O group indicated that LW >= 3.0 g was a significant risk factor for POBN (P= 0.049). For the Y group, no association between lung weight and POBN was observed. Conclusions: A LW >= 3.0 g is a significant risk factor for POBN in individuals aged >= 25 years.PIONEER BIOSCIENCE PUBL CO, Dec. 2016, JOURNAL OF THORACIC DISEASE, 8(12) (12), 3676 - 3681, English[Refereed]Scientific journal
- Nov. 2016, 肺癌, 56(6号) (6号), 590, Japanese肺結節切除標本内にびまん性特発性神経内分泌細胞過形成と多発tumorletを認めた1例[Refereed]Scientific journal
- Nov. 2016, 肺癌, 56(6号) (6号), 779, Japanese転移性脳腫瘍の発見から1年後に診断・手術に至ったpT1aN0M1bの原発性肺腺癌の1例[Refereed]Scientific journal
- Nov. 2016, 肺癌, 56(6号) (6号), 534, Japanese全身PET/MRI、MRI、PET/CT及び通常画像検査における胸腺上皮性腫瘍の病期診断能の比較[Refereed]Scientific journal
- Nov. 2016, 肺癌, 56(6号) (6号), 548, Japanese小細胞癌に対する外科的治療効果についての検討[Refereed]Scientific journal
- Nov. 2016, 肺癌, 56(6号) (6号), 717, Japanese左上区域支入口部腫瘍に対して完全鏡視下左上区域切除術を行った1例[Refereed]Scientific journal
- Nov. 2016, 肺癌, 56(6号) (6号), 497, Japanese胸壁浸潤肺癌手術に対する低侵襲化への工夫[Refereed]Scientific journal
- Nov. 2016, 肺癌, 56(6号) (6号), 842, Japanese急速に増大し縦隔偏位をきたした肺癌合併巨大肺嚢胞の一例[Refereed]Scientific journal
- Nov. 2016, 肺癌, 56(6号) (6号), 546, Japanese完全胸腔鏡下における予防的気管支断端被覆症例の検討[Refereed]Scientific journal
- Nov. 2016, 肺癌, 56(6号) (6号), 503, Japanese右房内に進展した巨大浸潤性胸腺腫に対し人工心肺を用い完全切除可能であった1例[Refereed]Scientific journal
- Nov. 2016, 肺癌, 56(6号) (6号), 862, Japanese咽頭転移を生じた大細胞神経内分泌癌の1例[Refereed]Scientific journal
- Background. This study compares long-term prognosis of intentional extended segmentectomy and lobectomy of clinical T1aN0M0 non-small cell lung cancer (NSCLC). Risk factors of local-regional recurrence are identified and segmentectomy outcomes are examined per segment. Methods. 164 intentional extended segmentectomies were compared with 73 lobectomies subcategorized by consolidation to maximum tumor diameter ratio (C/T) measured by computed tomographies. Preoperative characteristics were propensity score matched to evaluate local-regional recurrence-free survival using the log-rank test. Preoperative factors and surgical procedure were analyzed with the Cox proportional hazards regression model to identify independent predictor of local-regional recurrence. Local-regional recurrence per segment were assessed by Kaplan-Meier estimates between both groups. Results. No recurrences were observed for 46 C/T <= 0.5 segmentectomies. In 59 C/T >0.5 propensity scorematched pairs, 5-year local-regional recurrence-free survival rates of segmentectomies were 76.3%, versus 91.5% for lobectomies (p = 0.082). Multivariate analysis confirmed segmentectomies to be the only independent risk factor for local-regional recurrence-free probability (p = 0.020). Subset analysis reveals superior segmentectomies have significantly less local-regional recurrence (p = 0.029) than other segments and comparable prognosis to lower lobectomies. Left upper lobe segmentectomies also showed comparable prognosis to lobectomies. Segmentectomies in the right upper lobe and of basal segments showed significantly higher local recurrence (p = 0.001) than other segments. Basal segmentectomies showed significantly poor prognosis versus lower lobectomies (p = 0.005). Conclusions. For radiographically invasive right upper lobe or basal segment clinical T1a NSCLC, strict inclusion criteria is necessary for intentional segmentectomy. For superior and left upper lobe segments, however, segmentectomies may be preferred with prognosis comparable to lobectomies. (C) 2016 by The Society of Thoracic SurgeonsELSEVIER SCIENCE INC, Nov. 2016, ANNALS OF THORACIC SURGERY, 102(5) (5), 1702 - 1710, English[Refereed]Scientific journal
- Nov. 2016, 肺癌, 56(6号) (6号), 506, Japanese3次元肺癌CT検診用コンピューター支援診断システムの低線量化における再構成の影響に関する比較検討[Refereed]Scientific journal
- Nov. 2016, 肺癌, 56(6号) (6号), 673, Japanese3次元CTコンピューター体積測定システムの臨床応用 経過観察CTによる良・悪性結節鑑別能評価[Refereed]Scientific journal
- Aug. 2016, 日本気胸・嚢胞性肺疾患学会雑誌, 16(1号) (1号), 40, Japanesex Gateを用いた単孔式自然気胸手術の有用性の検討[Refereed]Scientific journal
- Apr. 2016, 肺癌, 56(2号) (2号), 138, Japanese病理組織診断で大細胞神経内分泌癌の中咽頭転移が判明した1例[Refereed]Scientific journal
- Apr. 2016, 日本呼吸器外科学会雑誌, 30(3号) (3号), P76 - 4, Japanese体細胞初期化因子導入による肺癌幹細胞誘導[Refereed]Scientific journal
- Apr. 2016, 日本呼吸器外科学会雑誌, 30(3号) (3号), P62 - 5, Japanese周術期に感染性大動脈瘤を合併した降下性壊死性縦隔炎の1手術例[Refereed]Scientific journal
- Apr. 2016, 日本呼吸器外科学会雑誌, 30(3号) (3号), P73 - 3, Japanese外傷性肺嚢胞に対して緊急手術を要した1例[Refereed]Scientific journal
- Apr. 2016, 日本呼吸器外科学会雑誌, 30(3号) (3号), V8 - 1, Japanese右鎖骨下動脈再建を要した肺尖部胸壁浸潤癌の1切除例[Refereed]Scientific journal
- Apr. 2016, 日本呼吸器外科学会雑誌, 30(3号) (3号), RO1 - 7, JapanesepT1N1非小細胞癌切除例におけるリンパ節病変の進展と予後に関する検討[Refereed]Scientific journal
- Apr. 2016, 日本呼吸器外科学会雑誌, 30(3号) (3号), RO1 - 1, Japanese1cm以下微小肺癌切除例の検討[Refereed]Scientific journal
- Feb. 2016, Ann Thorac Surg, 101(2) (2), 786 - 8, EnglishThe Use of Oxidized Regenerated Cellulose for Video-Assisted Thoracic Surgery[Refereed]Scientific journal
- Feb. 2016, Ann Thorac Surg, 101(2) (2), 520 - 6, EnglishIs Thymomectomy Alone Appropriate for Stage I (T1N0M0) Thymoma? Results of a Propensity-Score Analysis[Refereed]Scientific journal
- Feb. 2016, J Arrhythm, 32(1) (1), 62 - 6, EnglishEfficacy of bilateral thoracoscopic sympathectomy in a patient with catecholaminergic polymorphic ventricular tachycardia[Refereed]Scientific journal
- Jan. 2016, J Thorac Dis, 8(1) (1), E78 - 82, EnglishSurgical treatment of air way disease[Refereed]Scientific journal
- Recently, the use of paravertebral block (PVB) during thoracic surgery has been re-evaluated, as it is not inferior to epidural anaesthesia for postoperative pain control, and has been associated with fewer complications (e.g., hematoma of epidural, hypotension, urinary retention, postoperative nausea and vomiting). No reports have described intraoperative catheterization for PVB during single-incision thoracoscopic surgery (SITS) as distinct from thoracotomy or multi-ports video-assisted thoracoscopic surgery. We describe a case of SITS bullectomy using a chest wall pulley for lung excision to treat primary spontaneous pneumothorax and 25 catheterizations for PVB during SITS that have been performed since June 2013. Our novel technique is both easy and safe. It is ideal to combine PVB with SITS because both methods are less invasive.Springer-Verlag Tokyo, Jan. 2016, General Thoracic and Cardiovascular Surgery, 64(1) (1), 58 - 61, English[Refereed]Scientific journal
- Nov. 2015, Cancer Sci, 106(11) (11), 1625 - 34, EnglishSignificant role of Psf3 expression in non-small-cell lung cancer[Refereed]Scientific journal
- Aim We examined the advantages of thoracoscopy over thoracotomy in terms of perioperative outcomes and toleration of adjuvant chemotherapy. Methods Between April 2010 and March 2013, 657 patients with non-small-cell lung cancer who underwent lobectomy were classified into thoracoscopy (308 patients) and thoracotomy (349 patients) groups and compared. Results The thoracoscopy group had less blood loss compared to the thoracotomy group (p"‰< "‰0.001). When limiting the analysis to pathological stage I patients, the results were similar (p"‰< "‰0.001). In addition, the difference in blood loss between the 2 groups was greater in patients with severe pleural adhesions. The postoperative morbidity of the thoracoscopy group was significantly less than that of the thoracotomy group (13.3% vs. 21.2%, p"‰< "‰0.001), and this result was similar when analyzing the pathological stage I patients (12.6% vs. 20.6%, p"‰="‰0.001). A higher percentage of the thoracoscopy group received both the full planned course and dose of adjuvant chemotherapy compared to the thoracotomy group (84.2% vs. 65.8%, p"‰="‰0.032). Conclusions These results indicate that totally thoracoscopic lobectomy is the more beneficial surgical approach with regard to the incidence of postoperative complications and toleration of adjuvant chemotherapy.SAGE Publications Inc., Oct. 2015, Asian Cardiovascular and Thoracic Annals, 23(8) (8), 950 - 957, English[Refereed]Scientific journal
- Purpose: In patients with primary spontaneous pneumothorax (PSP), bullae are generally resected using autosutures under video-assisted thoracoscopic surgery (VATS). However, postoperative bulla neogenesis (POBN) along the staple line is not rare and is a factor promoting PSP recurrence. POBN is attributed to tension along the staple line, and we surmise that the resected lung volume affects this tension. Therefore, in this study, we retrospectively examined the relationship between POBN and the resected lung volume in patients who underwent surgical treatment of PSP. Methods: Between February 2011 and May 2015, 70 lung resection sites in 56 PSP patients who underwent primary VATS at our hospital were evaluated. POBN was diagnosed on high-resolution computed tomography 1 year postoperatively in principle. Results: POBN was detected at 26 of 70 (37.1 %) sites. On univariate analysis, lung weight ≥1.5 g, lung length ≥4.0 cm, resected site: apical, age < 25 years old and non-smoking habit were identified as significant, and the POBN rates for cases with lung weight ≥1.5 g or lung length ≥4.0 cm were 47.9 % (P = 0.004) and 44.1 % (P < 0.001), respectively. On multivariate analysis, lung weight ≥1.5 g was only significant factor for POBN (P = 0.043). Conclusion: A resected lung weight ≥1.5 g was only significant risk factor of POBN in patients with PSP.Springer Tokyo, Oct. 2015, General Thoracic and Cardiovascular Surgery, 63(10) (10), 572 - 575, English[Refereed]Scientific journal
- A thymoma is a neoplasm that arises from the epithelial cells of the thymus, and may cause various signs and symptoms dependent upon its local extent. A nontrau-matic hemothorax is extremely rare. The present study reports the case of a 77-year-old female who presented with an acute onset of chest pain. Imaging procedures revealed a mass occupying the anterior mediastinum and left hemithorax, and a left pleural effusion. Progressive anemia was noted following admission. Left hemothorax due to rupture of the anterior mediastinal mass was suspected, and emergency surgery was performed. Hemorrhage was observed on the cut surface of the tumor. An analysis of frozen sections indicated a thymoma, and a thymo-partial thymectomy was subsequently performed to remove as much of the hematoma as possible. The patient was discharged on post-operative day 13 following an uneventful recovery. The present case suggests that in previously healthy individuals, sudden-onset dyspnea and chest pain co-occurring with an acute widening of the mediastinum observed on roentgenograph may be indicative of a ruptured thymoma.SPANDIDOS PUBL LTD, Sep. 2015, ONCOLOGY LETTERS, 10(3) (3), 1810 - 1812, English[Refereed]Scientific journal
- OBJECTIVES: We evaluated the clinical benefit of segmentectomy for patients with cT1bN0M0 lung cancer. METHODS: We retrospectively reviewed the medical records of 178 patients who underwent lobectomy or segmentectomy for cT1bN0M0 lung adenocarcinoma and squamous cell carcinoma from January 1995 to December 2005. We investigated the association of surgical outcomes with the presence of pathological invasion. RESULTS: The median follow-up period was 93.4 months. Of 178 patients, 37 were scheduled for segmentectomy, but 6 of these patients were switched to receive lobectomy due to surgical N1 or N2 in 3 patients and insufficient surgical margins in 3 patients. In total, 31 patients underwent segmentectomy, and 147 underwent lobectomy. The 5-year overall survival (OS) was similar between the patients who underwent lobectomy (5-year OS, 81.6%) and segmentectomy (5-year OS, 77.4%, P = 0.73). Among pN0 patients without pathological invasion, there was no difference in OS between patients who underwent lobectomy (5-year OS, 89.9%) and segmentectomy (5-year OS, 88.9%, P = 0.80). In contrast, among pN0 patients with pathological invasion, OS was greater in patients who underwent lobectomy (5-year OS, 80.9%) than in those who underwent segmentectomy (5-year OS, 54.6% P = 0.19). Moreover, a significantly higher rate of local and local + distant recurrence was observed in patients who underwent segmentectomy (45%) than in those who underwent lobectomy (15%) in this group (P = 0.02). CONCLUSIONS: The results of our study suggest that segmentectomy may not be recommended for cT1b tumours if pathological invasion is suspected before surgery.European Association for Cardio-Thoracic Surgery, Jul. 2015, European Journal of Cardio-thoracic Surgery, 48(1) (1), 77 - 82, English[Refereed]Scientific journal
- 南江堂, Jul. 2015, 胸部外科, 68(7号) (7号), 546 - 549, Japanese縦隔成熟奇形腫胸腔内穿破の1例[Refereed]Scientific journal
- Jul. 2015, Interact Cardiovasc Thorac Surg, 21(1) (1), 34 - 9, EnglishEfficacy of adjuvant chemotherapy for lung adenocarcinoma patients with positive pleural lavage cytology findings[Refereed]Scientific journal
- Jul. 2015, Kyobu Geka, 68(7) (7), 546 - 9, English[Perforation of the Mediastinal Mature Teratoma;Report of a Case][Refereed]Scientific journal
- The lungs are dually perfused by the pulmonary artery and the bronchial arteries. This study aimed to test the feasibility of dual-perfusion techniques with the bronchial artery circulation and pulmonary artery circulation synchronously perfused using ex vivo lung perfusion (EVLP) and evaluate the effects of dual-perfusion on posttransplant lung graft function. Using rat heart-lung blocks, we developed a dual-perfusion EVLP circuit (dual-EVLP), and compared cellular metabolism, expression of inflammatory mediators, and posttransplant graft function in lung allografts maintained with dual-EVLP, standard-EVLP, or cold static preservation. The microvasculature in lung grafts after transplant was objectively evaluated using microcomputed tomography angiography. Lung grafts subjected to dual-EVLP exhibited significantly better lung graft function with reduced proinflammatory profiles and more mitochondrial biogenesis, leading to better posttransplant function and compliance, as compared with standard-EVLP or static cold preservation. Interestingly, lung grafts maintained on dual-EVLP exhibited remarkably increased microvasculature and perfusion as compared with lungs maintained on standard-EVLP. Our results suggest that lung grafts can be perfused and preserved using dual-perfusion EVLP techniques that contribute to better graft function by reducing proinflammatory profiles and activating mitochondrial respiration. Dual-EVLP also yields better posttransplant graft function through increased microvasculature and better perfusion of the lung grafts after transplantation.Blackwell Publishing Ltd, May 2015, American Journal of Transplantation, 15(5) (5), 1219 - 1230, English[Refereed]Scientific journal
- Apr. 2015, 日本気管食道科学会会報, 66(2号) (2号), s25, Japanese気道狭窄をきたした食道神経鞘腫の1例[Refereed]Scientific journal
- Mar. 2015, Eur J Radiol, 84(3) (3), 509 - 15, EnglishValue of diffusion-weighted MR imaging using various parameters for assessment and characterization of solitary pulmonary nodules[Refereed]Scientific journal
- Feb. 2015, Ann Thorac Cardiovasc Surg, epub, EnglishA Case of Benign Esophageal Schwannoma Causing Life-threatening Tracheal Obstruction[Refereed]Scientific journal
- Pleural lavage cytology as an independent prognostic factor in non-small-cell lung cancer patients with stage I disease and adenocarcinomaWe previously reported that cancer cells may be detected through pleural lavage cytology (PLC). In this study, we sought to re-examine the prognostic significance of the PLC status based on an extended dataset with an additional follow-up period. Pleural lavage following thoracotomy was cytologically examined in 1,317 consecutive patients who were diagnosed with NSCLC between 1987 and 2004 at the Thoracic Surgery Units of Kobe University Graduate School of Medicine and Hyogo Cancer Center. Among the investigated patients, 46 exhibited positive cytological findings. The prognosis of these patients was significantly worse compared to that of patients without positive PLC. Of the 844 pathological stage I patients, 18 had a positive PLC status and their prognosis was significantly worse compared to that of patients with stage I disease without positive PLC. In conclusion, positive PLC findings were associated with a poor prognosis and this finding was significant for patients with stage I disease. These results suggest the need for PLC status evaluation during staging and treatment planning in patients with NSCLC.Jan. 2015, Mol Clin Oncol, 3(1) (1), 244 - 248, English, International magazine[Refereed]Scientific journal
- The histological subtype of non-small-cell lung cancer (NSCLC) is a significant factor when selecting treatment strategies. However, cases are occasionally encountered that are diagnosed as 'not otherwise specified' (NOS) prior to surgery, due to an uncertain histological subtype. The present study investigated the prognostic significance of the NOS subtype for patients with resectable NSCLC. Between 2001 and 2011, 1,913 patients were diagnosed with NSCLC using transbronchial biopsy and underwent surgical resection at two facilities in Japan. Of these patients, 151 (7.9%) were pre-operatively diagnosed with NSCLC-NOS (NOS group) and the remainder had confirmed histological subtypes (confirmed group). The present study compared the clinicopathological features and prognoses of these groups. Analyses of resected specimens revealed that pleomorphic cell carcinoma, large cell neuroendocrine cell carcinoma, large-cell carcinoma and adenosquamous carcinoma were significantly more common in the NOS group than in the confirmed group (P<0.001, P=0.002, P=0.019 and P=0.014, respectively). The five-year survival rate was significantly poorer in the NOS group (60.5 vs. 67.1%; P=0.010), particularly for stage I disease (70.8 vs. 80.7%; P=0.007). The results of a multivariate analysis of overall survival indicated that NOS was a significant independent prognostic factor (hazard ratio, 1.40; 95% confidence interval, 1.02-1.86; P=0.041). These results indicated that pre-operative NOS was significantly associated with poorer survival, including for stage I disease. In conjunction with other clinicopathological parameters, NOS can be a useful prognostic factor when deciding on a treatment strategy for NSCLC.SPANDIDOS PUBL LTD, Sep. 2014, ONCOLOGY LETTERS, 8(3) (3), 1017 - 1024, English[Refereed]Scientific journal
- Sirtuin 1 (Sirt1) is a nicotinamide adenine dinucleotide-dependent class III histone deacetylase. It reportedly can repress cellular apoptosis and senescence to affect DNA repair, stress response and aging. Notably, previous data have indicated that Sirt1 is both a tumor promoter and a tumor suppressor in tumorigenesis. However, Sirt1 expression in primary lung adenocarcinoma remains unknown. Immunohistochemical staining was performed to investigate Sirt1 expression in cancer cells in 125 consecutive resected cases of primary lung adenocarcinoma. Sirt1 expression was found to be increased in 26(20.8%) of the 125 cases, which correlated significantly with five clinicopathological factors: Ki67 index, hypoxia-inducible factor 1 (HIF1) molecule expression, tumor-node-metastasis (TNM) classification, pulmonary vein invasion and lymphatic duct invasion. In the Sirt1-positive expression group, Sirt1 expression correlated with a higher Ki67 index and higher TNM classification, particularly for lymph node invasion and metastasis, and with a higher number of pulmonary vein invasion and lymphatic duct invasion. Additionally, a negative correlation was identified between HIF1-positive expression and Sirt1-negative expression. These results indicate that Sirt1 overexpression plays a promotional role in tumorigenesis and is closely associated with invasion and metastasis and, thus, it may be associated with prognosis.SPANDIDOS PUBL LTD, Jul. 2014, ONCOLOGY LETTERS, 8(1) (1), 387 - 393, English[Refereed]Scientific journal
- Jun. 2014, Br J Radiol, 87(1038) (1038), 20130307, EnglishDiffusion-weighted imaging vs STIR turbo SE imaging: capability for quantitative differentiation of small-cell lung cancer from non-small-cell lung cancer[Refereed]Scientific journal
- Purpose: To evaluate and compare the capability of diffusion-weighted MR imaging (DWI) and CT for assessment of management needs for anterior mediastinal solitary tumors. Materials and methods: Thirty-five patients with pathologically confirmed anterior mediastinal tumors were enrolled. The tumors were divided into two groups according to need for management: tumors not needing further intervention or treatment (group A; thymoma type A, AB and B1) and tumors needing further intervention and treatment (group B; other thymoma types and malignancies). The apparent diffusion coefficient (ADC) of each tumor was measured, and probabilities of malignancy and need for further intervention and treatment were visually assessed on CT. The differences in ADCs between group A and B and between malignancies and thymomas in group B were evaluated with the Mann-Whitney's U-test. Feasible threshold values for differentiation of group B from group A and distinguishing malignancies from thymomas assessed as group B were determined by the ROC-based positive test, and McNemar's test was used for comparing diagnostic capabilities of DWI with those of CT. Results: ADCs for the two groups were significantly different (p < 0.001). Application of the threshold value for differentiation of group B from A showed no significant difference (p > 0.05). Application of the feasible threshold value for distinguishing malignant from thymomas assessed as group B showed that specificity (76.9%) and accuracy (85.2%) of DWI were significantly better than those of visual score (p < 0.05). Conclusion: DWI has useful potential for the assessment of management needs for anterior mediastinum solitary tumors as well as CT. (C) 2014 Elsevier Ireland Ltd. All rights reserved.ELSEVIER IRELAND LTD, May 2014, EUROPEAN JOURNAL OF RADIOLOGY, 83(5) (5), 835 - 842, English[Refereed]Scientific journal
- Dec. 2013, Interact Cardiovasc Thorac Surg, 17(6) (6), 974 - 80, EnglishThe efficacy of 320-detector row computed tomography for the assessment of preoperative pulmonary vasculature of candidates for pulmonary segmentectomy[Refereed]Scientific journal
- Jul. 2013, Interact Cardiovasc Thorac Surg, 17(suppl 1) (suppl 1), S1 - S62, English[Refereed]Scientific journal
- Nectin-like molucule-5 (Necl-5) is an immunoglobulin-like molecule that was originally identified as a poliovirus receptor and is often upregulated in cancer cells. It has been said that Necl-5 plays a role in not only cell-cell adhesion, but also cell migration, proliferation, and metastasis. In this study, we used a bronchioloalveolar carcinoma (BAC) cell line and fibroblasts to assess the expression of Necl-5 in the development of cancer-stroma communication by using an easy-to-prepare double-layered collagen gel hemisphere (DL-CGH) system that enables visualization of cell migration during invasion. The expression of Necl-5 was higher in BAC cells than in fibroblasts. This tendency didn't change even when the BAC cells were mixed with fibroblasts. To assess the role of Necl-5 in the invasive activity of the BAC cells, we knocked down its expression using RNA interference (RNAi). The invasion assay with DL-CGH revealed that inhibition of Necl-5 expression in the BAC cells was associated with suppressed invasiveness. In addition, Necl-5 knockdown inhibited the movement and proliferation of the BAC cells. Necl-5 expression in lung cancer cells is crucial for their invasiveness in the cancer-stromal interaction, suggesting that Necl-5 could be a favorable molecular target for the suppression of invasiveness in lung adenocarcinoma. © 2013 Elsevier Inc.Apr. 2013, Experimental and Molecular Pathology, 94(2) (2), 330 - 335, English[Refereed]Scientific journal
- Apr. 2013, Cancer Med, 2(2) (2), 144 - 54, EnglishSlug increases sensitivity to tubulin-binding agents via the downregulation of βIII and βIVa-tubulin in lung cancer cells[Refereed]Scientific journal
- Mar. 2013, J Thorac Cardiovasc Surg, 145(3) (3), 839 - 46, EnglishImmunohistochemical studies of pulmonary large cell neuroendocrine carcinoma: a possible association between staining patterns with neuroendocrine markers and tumor response to chemotherapy[Refereed]Scientific journal
- Psf3 is a member of the evolutionarily conserved heterotetrameric complex GINS (Go-lchi-Ni-San), which consists of SId5, Psf1, Psf2, and Psf3. Previous studies have suggested that some GINS complex members are upregulated in cancer, but the status of Ps13 expression in lung adenocarcinoma has not been investigated. The objective of the current study was to determine whether Psf3 plays a role in lung adenocarcinoma by investigating clinical samples. We investigated the status of Psf3 expression in cancer cells of 125 consecutive resected lung adenocarcinomas by immunohistochemistry. Increased Psf3 expression was observed in 27(21.6%) of the 125 cases. Further, univariate analysis and log-rank test indicated a significant association between Psf3 expression and lower overall survival rate (P=0.0001 and P<0.0001, respectively). Multivariate analysis also indicated a statistically significant association between increased Psf3 expression and lower overall survival rate (hazard ratio, 5.2; P=0.0027). In a subgroup analysis of only stage I patients, increased Psf3 expression was also significantly associated with a lower overall survival rate (P=0.0008, log-rank test). Moreover, the Ki67 index level was higher in the Psf3-positive group than in the Psf3-low positive group (P<0.0001, Mann-Whitney U-test). Our results indicated that Psf3 can serve as a prognostic biomarker in lung adenocarcinoma. (C) 2012 Elsevier Ireland Ltd. All rights reserved.ELSEVIER IRELAND LTD, Jan. 2013, LUNG CANCER, 79(1) (1), 77 - 82, English[Refereed]Scientific journal
- Ewing's sarcoma family tumors (ESFT), which include Ewing's sarcoma and primitive neuroectodermal tumors (PNET), have been reported to originate in a variety of sites, mostly in the extremities. Previous reports have shown ESFT originating in the thoracic region, such as chest wall and peripheral lung. We herein report the first case of the ESFT that originated in the main bronchus. Endobronchial snare resection was followed by five courses of chemotherapy (VDC-IE; including vincristine, doxorubicin, cyclophosphamide, ifosfamide and etoposide) and sequential radiation. After the treatment, the patient's condition has improved, and he has remained disease-free for the past year.WILEY-BLACKWELL, Nov. 2012, THORACIC CANCER, 3(4) (4), 353 - 356, English[Refereed]Scientific journal
- Oct. 2012, 肺癌, 52(5号) (5号), 605, Japanese肺癌患者の遠隔転移・再発診断における全身脂肪抑制造影Quick 3DによるMRIの有用性に関する検討Research society
- Oct. 2012, 肺癌, 52(5号) (5号), 724, Japanese当科における傍腫瘍性神経症候群合併小細胞肺癌の臨床的検討Research society
- (NPO)日本肺癌学会, Oct. 2012, 肺癌, 52(5号) (5号), 609 - 609, JapaneseAdaptive Iterative Dose Reduction 3Dの低線量CTにおける有用性の検討[Refereed]Symposium
- (NPO)日本肺癌学会, Jun. 2012, 肺癌, 52(3) (3), 353 - 354, Japanese肺内転移やリンパ節転移との鑑別が困難であった扁平上皮腺上皮性混合型乳頭腫の1例Research society
- Background: We investigated the prognostic significance of the immunoglobulin-like cell adhesion molecule nectin-3, a regulator of the formation of adherens junctions, in human lung adenocarcinoma. Methods: Tumor-tissue samples of 127 patients with surgically resected lung adenocarcinoma were used for analysis of the proteins expression by immunohistochemistry. Results: Of the 127 patients, 25% showed membranous expression of nectin-3, and others showed negative or cytoplasmic expression. Membranous expression of nectin-3 was found to be a prognostic factor for decreased overall survival on univariate analysis (P = 0.001). Multivariate Cox proportional hazards model analyses also revealed that membranous expression of nectin-3 turned out to be an independent prognostic factor (P = 0.048). Moreover, in tumors expressing membranous nectin-3, some tumors did not co-localize with E-cadherin, and the patients of such tumors showed poorer prognosis than other patients for overall survival on univariate analysis (P < 0.03). Conversely, membranous expression of nectin-3 with E-cadherin co-localization was found to associate with good prognosis of patients. Conclusion: Membranous expression of nectin-3 was an independent prognostic factor of lung adenocarcinoma, and it might play an important role in progression of the tumor.WILEY-BLACKWELL, May 2012, THORACIC CANCER, 3(2) (2), 175 - 181, English[Refereed]Scientific journal
- Nov. 2011, Radiology, Vol. 261, No. 2, pp. 605-15, EnglishN stage disease in patients with non-small cell lung cancer: efficacy of quantitative and qualitative assessment with STIR turbo spin-echo imaging, diffusion-weighted MR imaging, and fluorodeoxyglucose PET/CT[Refereed]Scientific journal
- Lung cancer is one of the most common cancers in the world, but no good clinical markers that can be used to diagnose the disease at an early stage and predict its prognosis have been found. Therefore, the discovery of novel clinical markers is required. In this study, metabolomic analysis of lung cancer patients was performed using gas chromatography mass spectrometry. Serum samples from 29 healthy volunteers and 33 lung cancer patients with adenocarcinoma (n = 12), squamous cell carcinoma (n = 11), or small cell carcinoma (n = 10) ranging from stage I to stage IV disease and lung tissue samples from 7 lung cancer patients including the tumor tissue and its surrounding normal tissue were used. A total of 58 metabolites (57 individual metabolites) were detected in serum, and 71 metabolites were detected in the lung tissue. The levels of 23 of the 58 serum metabolites were significantly changed in all lung cancer patients compared with healthy volunteers, and the levels of 48 of the 71 metabolites were significantly changed in the tumor tissue compared with the non-tumor tissue. Partial least squares discriminant analysis, which is a form of multiple classification analysis, was performed using the serum sample data, and metabolites that had characteristic alterations in each histological subtype and disease stage were determined. Our results demonstrate that changes in metabolite pattern are useful for assessing the clinical characteristics of lung cancer. Our results will hopefully lead to the establishment of novel diagnostic tools. (C) 2011 Elsevier Ireland Ltd. All rights reserved.ELSEVIER IRELAND LTD, Nov. 2011, LUNG CANCER, 74(2) (2), 284 - 292, English[Refereed]Scientific journal
- Sep. 2011, Eur J Radiol, 79(3) (3), 473 - 9, EnglishNon-small cell carcinoma: comparison of postoperative intra- and extrathoracic recurrence assessment capability of qualitatively and/or quantitatively assessed FDG-PET/CT and standard radiological examinations[Refereed]Scientific journal
- May 2011, Cancer Sci., 102(5):1101-6., EnglishOncogenic phosphatase Wip1 is a novel prognostic marker for lung adenocarcinoma patient survival.[Refereed]Scientific journal
- Feb. 2011, Exp Mol Pathol., 90(1):91-6, EnglishMT1-MMP plays an important role in an invasive activity of malignant pleural mesothelioma cell.[Refereed]Scientific journal
- Feb. 2011, Radiology, Vol. 258, No. 2, pp. 599-609, EnglishDifferentiation of malignant and benign pulmonary nodules with quantitative first-pass 320-detector row perfusion CT versus FDG PET/CT[Refereed]Scientific journal
- Jan. 2011, Eur J Radiol, 77(1) (1), 97 - 104, EnglishState-of-the-art radiological techniques improve the assessment of postoperative lung function in patients with non-small cell lung cancer[Refereed]Scientific journal
- Descending necrotizing mediastinitis is a critical infection and the mortality rate remains high. Early aggressive surgical drainage and antibiotic therapy are essential for treatment. We evaluated the efficiency of transthoracic drainage using a minimally invasive technique in 11 cases of descending necrotizing mediastinitis between May 2002 and March 2008. We performed a right-side minithoracotomy with thoracoscopic assistance, and the mediastinum was thoroughly drained. The length of hospitalization ranged from 30 to 117 days. The postoperative course was good in all patients, and the outcome was favorable. All patients were discharged without major complications. We recommend employing a minithoracotomy with thoracoscopic assistance for aggressive treatment of descending necrotizing mediastinitis. © 2011 The Author(s).2011, Asian Cardiovascular and Thoracic Annals, 19(3-4) (3-4), 228 - 231, English[Refereed]Scientific journal
- May 2010, Cancer Sci., 101(5):1326-30., EnglishOverexpression of Necl-5 correlates with unfavorable prognosis in patients with lung adenocarcinoma.[Refereed]Scientific journal
- In this study, chemosensitivity tests were performed on both primary lesions (PLs) and lymph node metastases (LMs) from surgically resected non-small cell lung cancer (NSCLC) Differences between the results obtained were evaluated Operative specimens were obtained from 13 patients with NSCLC [6 with squamous cell carcinoma (SQ) and 7 with adenocarcinoma (AD)] whose lymph nodes were confirmed to be positive for metastasis Both the PL and LM from the same patient were examined immediately after resection The collagen gel droplet-embedded culture drug sensitivity test (CD-DST) was used as the chemosensitivity test against six anticancer drugs [5-fluorouracil (5-FU), cisplatin, gemcitabine, docetaxel, vinorelbine and SN-38 (an active metabolite of irinotecan)] When the growth rate, determined by the T/C ratio (T, signal for viable cells in the treated group and C, signal in the control) was less than 50%, the tumor cells were considered to be sensitive to the drug Only in 4 cases (2 SQ and 2 AD) was the chemosensitivity of the primary lesion identical to that of LM In the SQ cases, chemosensitivity of the primary lesions to 5-FU tended to be consistent with that of LMs In contrast, the primary lesions in 4 of the 7 AD cases were negative for chemosensitivity to 5-FU, however, LMs were sensitive In many cases, the chemosensitivity of the PLs to each anticancer drug differed from that of the LMs In conclusion, both primary and metastatic tumors should be examined to ensure maximum clinical efficacy of in vitro drug-sensitivity testing for adjuvant chemotherapy after complete resection of n1 and n2 NSCLCSPANDIDOS PUBL LTD, Mar. 2010, ONCOLOGY LETTERS, 1(2) (2), 345 - 349, English[Refereed]Scientific journal
- Feb. 2010, Cancer, 116(4):896-902., EnglishNonsynonymous single nucleotide polymorphisms in DNA damage repair pathways and lung cancer risk.[Refereed]Scientific journal
- Jan. 2010, ONCOLOGY LETTERS, Vol. 1, No. 1, pp. 345-349, EnglishChemosensitivity of Lung Cancer: Differences between Primary Tumor and Lymph Node MetastasisScientific journal
- Jun. 2009, Oncol Rep, 22(1):57-64., EnglishExpression and localization of FOXO1 in non-small cell lung cancer.[Refereed]Scientific journal
- Apr. 2009, 日本呼吸器外科学会雑誌, 23巻, 3号, pp. 488-488, Japanese断端再発のリスクを考慮した部分切除法(露天掘り法)International conference proceedings
- Mar. 2009, 大和証券ヘルス財団研究業績集, 巻, 32号, pp. 153-158, Japanese2層化コラーゲンゲル半球法を用いた癌細胞浸潤のメカニズムの研究 肺癌浸潤における癌宿主インターフェイスの役割を中心にしてScientific journal
- Feb. 2009, 日本外科学会雑誌, 110巻, 臨増2, pp. 773-773, JapaneseDamage repair pathwayにおけるNon-synonymous SNPと肺腺癌の発生についての検討International conference proceedings
- Nov. 2008, Biochemical and biophysical research communications, Vol. 376, No. 3, pp. 590-4, EnglishRad9 is upregulated and plays protective roles in an acute lung injury model[Refereed]Scientific journal
- Nov. 2008, Oncol Rep., 20(5):1047-52., EnglishDNA damage sensor protein hRad9, a novel molecular target for lung cancer treatment.[Refereed]Scientific journal
- Oct. 2008, 肺癌, 48巻, 5号, pp. 447-447, Japanese非小細胞肺癌患者における全身FDG-PET/CTの術後再発診断能に関する検討International conference proceedings
- Oct. 2008, 肺癌, 48巻, 5号, pp. 583-583, Japanese胸部MRIにおける肺腺癌の結節同定能と組織分類の検討 拡散強調像とSTIR像の比較International conference proceedings
- Oct. 2008, European radiology, Vol. 18, No. 10, pp. 2120-31, EnglishQuantitative and qualitative assessment of non-contrast-enhanced pulmonary MR imaging for management of pulmonary nodules in 161 subjects[Refereed]Scientific journal
- Oct. 2008, Annals of thoracic and cardiovascular surgery, Vol. 14, No. 5, pp. 319-21, EnglishEffective chemotherapy based on a chemosensitivity test for malignant pleural mesothelioma[Refereed]Scientific journal
- Oct. 2008, 肺癌, 48巻, 5号, pp. 584-584, JapaneseDynamic MRI vs.CT vs.RI 非小細胞肺癌患者の術後肺機能予測能に関する検討International conference proceedings
- Jun. 2008, Journal of magnetic resonance imaging, Vol. 27, No. 6, pp. 1284-95, EnglishDynamic MRI, dynamic multidetector-row computed tomography (MDCT), and coregistered 2-[fluorine-18]-fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET)/CT: comparative study of capability for management of pulmonary nodules[Refereed]Scientific journal
- Apr. 2008, 日本呼吸器外科学会雑誌, 22巻, 3号, pp. 452-452, Japanese非小細胞肺癌におけるFOXO1発現の意義International conference proceedings
- Apr. 2008, 日本呼吸器外科学会雑誌, 22巻, 3号, pp. 521-521, Japanese転移性肺腫瘍に対する粒子線治療後のサルベージ手術International conference proceedings
- Apr. 2008, 日本気管食道科学会会報, 59巻, 2号, pp. 257-257, Japanese最近当科で経験した縦隔炎・縦隔膿瘍の症例International conference proceedings
- Apr. 2008, 日本呼吸器外科学会雑誌, 22巻, 3号, pp. 452-452, Japanese原発性肺癌におけるthymidylate synthase,Dihydropyrimidine dehydrogenaseの解析International conference proceedings
- Apr. 2008, 日本呼吸器外科学会雑誌, 22巻, 3号, pp. 389-389, Japanese下行性壊死性縦隔炎に対する徹底的な縦隔ドレナージ手術International conference proceedings
- Apr. 2008, European Journal Of Cardio-Thoracic Surgery, Vol. ?, No. ?, pp. ?-?, EnglishThe optimal timing to resect pulmonary metastasisScientific journal
- Oct. 2007, 肺癌, 47巻, 5号, pp. 464-464, Japanese肺癌研究 基礎から臨床へ BAC cell浸潤におけるTumor-host interfaceの役割に関しての実験的検討International conference proceedings
- Oct. 2007, Cell Communication And Adhesion, Vol. 14, No. 4, pp. 157-67, EnglishDouble-layered collagen gel hemisphere for cell invasion assay: successful visualization and quantification of cell invasion activity[Refereed]Scientific journal
- Sep. 2007, Gen Thorac Cardiovasc Surg, Vol. 55, No. 9, pp. 366-9, EnglishSuccessful treatment of descending necrotizing mediastinitis[Refereed]Scientific journal
- Aug. 2007, 日本癌学会総会記事, 巻, 66回, pp. 330-331, Japanese間質への浸潤傾向を伴った細気管支肺胞上皮癌におけるcancer-stroma interactionに関する実験的検討(In-vitro visualization of cancer-stroma interaction in bronchiolo-alveolar carcinoma (BAG) with invasive component)(英語)International conference proceedings
- May 2007, Human Gene Therapy, Vol. 18, No. 5, pp. 389-400, EnglishModification of the Rb-binding domain of replication-competent adenoviral vector enhances cytotoxicity against human esophageal cancers via NF-kappaB activityScientific journal
- Mar. 2007, Arteriosclerosis, Thrombosis, And Vascular Biology, Vol. 27, No. 3, pp. 548-55, EnglishControlled release of basic fibroblast growth factor from gelatin hydrogel sheet improves structural and physiological properties of vein graft in ratScientific journal
- Nov. 2006, 肺癌, 46巻, 5号, pp. 590-590, Japanese肺癌の肺門部気管支血管周囲組織浸潤と断端および予後に関する検討International conference proceedings
- Nov. 2006, 肺癌, 46巻, 5号, pp. 588-588, Japanese当院における転移性肺腫瘍の検討International conference proceedings
- Nov. 2006, 肺癌, 46巻, 5号, pp. 477-477, Japanese新しいCT,MR技術の肺癌診断への応用 STIR Turbo SE Imaging vs.Co-registered FDG-PET/CT 非小細胞肺癌におけるN因子診断能の検討International conference proceedings
- Nov. 2006, 肺癌, 46巻, 5号, pp. 652-652, Japanese再発肺癌の手術戦略International conference proceedings
- Nov. 2006, 肺癌, 46巻, 5号, pp. 598-598, Japanese原発性肺癌の大動脈浸潤が疑われ人工気胸術(気胸CT)を行った1例International conference proceedings
- Nov. 2006, 肺癌, 46巻, 5号, pp. 628-628, JapaneseSTIR turbo SEを用いた非造影MRIによる肺結節の半定量的良・悪性診断能の検討International conference proceedings
- Sep. 2006, 日本癌学会総会記事, 巻, 65回, pp. 439-439, Japanese非小細胞肺癌におけるFOXO1を介したアポトーシスに関する実験的検討International conference proceedings
- Sep. 2006, The Japanese Journal of THORACIC AND CARDIOVASCULAR SURGERY, 54巻, Suppl., pp. 479-479, JapaneseDNA damage sensor蛋白質hRad9の肺癌に対する分子標的としての可能性の検討International conference proceedings
- Aug. 2006, 肺癌, 46巻, 4号, pp. 390-390, Japanese腫瘍との鑑別を要した良性胸膜病変の2例International conference proceedings
- Aug. 2006, 肺癌, 46巻, 4号, pp. 385-385, JapaneseHRAD9における肺腺癌に特異的な1塩基多型International conference proceedings
- May 2006, 日本呼吸器外科学会雑誌, 20巻, 3号, pp. 810-810, Japanese非小細胞肺癌における術後再発症例の外科治療についての検討International conference proceedings
- May 2006, 日本呼吸器外科学会雑誌, 20巻, 3号, pp. 785-785, Japanese肺切除を回避できた右主気管支断裂・広範欠損に対する1手術例International conference proceedings
- May 2006, 日本呼吸器外科学会雑誌, 20巻, 3号, pp. 861-861, Japanese当科における呼吸器外科手術の合併症の予防策 最近5年間の合併症率と共にInternational conference proceedings
- May 2006, 日本呼吸器外科学会雑誌, 20巻, 3号, pp. 943-943, Japanese下行大動脈の全周囲に沿って発育した炎症性悪性線維性組織球腫の1手術例International conference proceedings
- May 2006, 日本呼吸器外科学会雑誌, 20巻, 3号, pp. 826-826, Japanese横隔膜縫縮術が奏功した術後横隔神経麻痺の3例International conference proceedings
- Apr. 2006, 肺癌, 46巻, 2号, pp. 181-181, Japanese経口摂取不能,PS3の肺腺癌再発に対しゲフィチニブ投与により著明なPS改善を認めた1例International conference proceedings
- Mar. 2006, 日本外科学会雑誌, 107巻, 臨増2, pp. 582-582, Japanese非小細胞肺癌の原発巣と転移リンパ節における抗癌抗感受性の検討International conference proceedings
- Mar. 2006, Cancer, Vol. 106, No. 5, pp. 1117-1122, EnglishHis239Arg SNP of HRAD9 is associated with lung adenocarcinomaScientific journal
- Mar. 2006, 日本外科学会雑誌, 107巻, 臨増2, pp. 533-533, JapaneseDNA damage repair gene HRAD9における肺腺癌に特異的な1塩基多型International conference proceedings
- Nov. 2005, 肺癌, 45巻, 5号, pp.603-603, Japanese原発性肺癌におけるHRAD9遺伝子の解析International conference proceedings
- Nov. 2005, 肺癌, 45巻, 5号, pp. 657-657, Japanese悪性胸膜中皮腫の診断と治療International conference proceedings
- Nov. 2005, 肺癌, 45巻, 5号, pp. 644-644, JapanesePleomorphic carcinoma of the lung 9手術例の検討International conference proceedings
- Nov. 2005, 肺癌, 45巻, 5号, pp. 591-591, JapaneseGGAの経過観察中に第2癌の発見された同時多発肺癌の1例International conference proceedings
- Nov. 2005, Oncology Reports, Vol. 14, No. 5, pp. 1155-1163, EnglishE1B-deleted adenovirus replicates in p53-deficient lung cancer cells due to the absence of apoptosis[Refereed]Scientific journal
- Oct. 2005, 肺癌, 45巻, 6号, pp. 770-770, Japanese肺癌術後10年以上経過して再発の認められた1例International conference proceedings
- Sep. 2005, 日本癌学会64回総会記事, pp.70-70, Japanese肺癌におけるDNA damage sensor蛋白Rad9発現の意義International conference proceedings
- Sep. 2005, The Japanese Journal of THORACIC AND CARDIOVASCULAR SURGERY, 53巻, Suppl.II, pp. 309-309, Japanese急性縦隔炎の4手術例International conference proceedings
- May 2005, 日本呼吸器外科学会雑誌, 19巻, 3号, pp. 398-398, Japanese肺腺癌における細胞周期制御蛋白p21およびその転写活性化因子の発現異常の検討International conference proceedings
- May 2005, 日本呼吸器外科学会雑誌, 19巻, 3号, pp. 368-368, Japanese原発性肺癌と心大血管病変を同時に有した症例に対する外科療法の検討International conference proceedings
- Apr. 2005, 日本外科学会雑誌, 106巻, 臨増, pp. 380-380, Japanese当院における同時多発肺癌症例に対する検討International conference proceedings
- Mar. 2005, The Japanese Journal of THORACIC AND CARDIOVASCULAR SURGERY, 53巻, Suppl.I, pp. 77-77, Japanese鈍的胸部外傷後の遅発性血胸に対する緊急手術症例International conference proceedings
- Mar. 2005, 日本病理学会会誌, 94巻, 1号, pp. 177-177, Japanese転写調節因子による腫瘍の表現形質と悪性度の修飾 細胞周期制御蛋白p21およびその転写活性化因子の発現異常 肺腺癌における表現形質と悪性度の変化International conference proceedings
- Mar. 2005, The Japanese Journal of THORACIC AND CARDIOVASCULAR SURGERY, 53巻, Suppl.I, pp. 77-77, Japanese縦隔内異物・膿瘍の1手術例International conference proceedings
- Mar. 2005, The Japanese Journal of THORACIC AND CARDIOVASCULAR SURGERY, 53巻, Suppl.I, pp. 50-50, JapanesePryce III型肺葉内肺分画症の1手術例International conference proceedings
- Feb. 2005, 肺癌, 45巻, 1号, pp. 97-98, Japanese孤立性肺転移で発見された不顕性甲状腺乳頭癌の1例International conference proceedings
- 2005, Cancer, Vol. 103, No. 1, pp. 126-132, EnglishAccumulation of hRad9 protein in the nuclei of nonsmall cell lung carcinoma cells[Refereed]Scientific journal
- Oct. 2004, 肺癌, 44巻, 5号, pp. 657-657, Japanese非小細胞肺癌の原発巣と転移リンパ節における抗癌剤感受性の検討International conference proceedings
- Oct. 2004, 肺癌, 44巻, 6号, pp. 715-715, Japanese原発性肺腺癌におけるp53発現異常と細胞分裂能の関連性International conference proceedings
- Oct. 2004, 肺癌, 44巻, 5号, pp. 424-424, Japanese経気管支肺生検と切除肺の組織型,亜型診断の比較検討International conference proceedings
- Oct. 2004, 肺癌, 44巻, 5号, pp. 343-343, JapaneseSTIR Turbo SE MRI vs.FDG-PET 非小細胞肺癌における術前転移リンパ節診断能の比較International conference proceedings
- Sep. 2004, The Japanese Journal of THORACIC AND CARDIOVASCULAR SURGERY, 52巻, Suppl., pp. 262-262, Japanese悪性胸膜中皮腫における進展形式の検討とstagingの問題点International conference proceedings
- Sep. 2004, Cancer Science, 95巻, Suppl., pp. 151-151, JapanesehRad9蛋白質の生物学的特性と癌細胞における機能International conference proceedings
- Apr. 2004, 日本呼吸器外科学会雑誌, 18巻, 3号, pp. 321-321, JapaneseRib cross thoracotomyによる悪性胸膜中皮腫の1手術例International conference proceedings
- Oct. 2003, The Japanese Journal of THORACIC AND CARDIOVASCULAR SURGERY, 51巻, 増刊, pp. 457-457, Japanese同時期に発見された肺癌と心大血管病変に対する外科療法の検討International conference proceedings
- Oct. 2003, 肺癌, 43巻, 5号, pp. 509-509, Japanese原発性肺癌におけるDNA damage sensor蛋白質発現の分析International conference proceedings
- Sep. 2003, Proceedings Of The National Academy Of Sciences Of The United States Of America, Vol. 100, No. 18, pp. 10237-10, EnglishThe alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA[Refereed]Scientific journal
- Apr. 2003, 日本呼吸器外科学会雑誌, 17巻, 3号, pp. 437-437, Japanese原発性肺肉腫の二手術例International conference proceedings
- Feb. 2003, Proceedings Of The National Academy Of Sciences Of The United States Of America, Vol. 100, No. 4, pp. 1633-1638, EnglishLoading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro[Refereed]Scientific journal
- Apr. 2018, 日本呼吸器外科学会雑誌, 32(3号) (3号), P32 - 3, Japanese悪性腫瘍との鑑別を要した肺ヒストプラズマ症の一例[Refereed]Meeting report
- Jul. 2015, 日本気胸・嚢胞性肺疾患学会雑誌, 15(1号) (1号), 61, Japanese自然気胸に対するx Gateの使用経験[Refereed]Meeting report
- Mar. 2015, オペナーシング, 臨時増刊, 189 - 198, Japanese【呼吸器外科の手術看護パーフェクトマニュアル】 (第2章)実践編 術式別の術中看護マニュアル 気胸に対する手術Introduction scientific journal
- Dec. 2014, 胸部外科, 67(13) (13), 1133, Japaneseまい・てくにっく 肺靱帯切離と#9郭清のポイントIntroduction scientific journal
- Pulmonary large cell neuroendocrine carcinoma (LCNEC) is a rare and aggressive malignant tumor, which was proposed as a novel type of neuroendocrine tumor in 1991. Although it is categorized as a non-small cell lung carcinoma, the precise pathological condition is unknown due to its rare occurrence. The present study outlines the case of a patient presenting with an LCNEC that exhibited pagetoid spread from the region of the primary tumor to the bronchial epithelium (distance, >30 mm). The pagetoid spread was unconfirmed preoperatively, however, was identified by intraoperative rapid diagnosis. This caused us to suffer the perioperative decision of additional resection and resulted in an incomplete resection, as suture of the bronchus was not possible. Pagetoid spread, which is often apparent in the breast, presents as a rare pattern of infiltration of cancer cells when a massive carcinoma is identified beneath the intraepithelial spread. Although preoperative diagnosis of pagetoid spread is difficult due to its rarity and undefined clinical features, it is important for surgeons and pathologists treating lung cancer patients to be aware of potential pagetoid spread in the thoracic region.SPANDIDOS PUBL LTD, Dec. 2014, ONCOLOGY LETTERS, 8(6) (6), 2621 - 2623, English[Refereed]Introduction commerce magazine
- Apr. 2014, 呼吸器ケア, 臨時増刊(217) (217), 217 - 227, Japanese【ナースのためのパーフェクトガイド 呼吸器外科の術前術後ケア】 (第3章)呼吸器外科・看護の各論 疾患 嚢胞性疾患・気胸Introduction scientific journal
- 肺手術前の高解像度 3D-CTによる肺血管同定の有用性術前評価のための三次元シミュレーション画像作成において、320列エリアエリアディテクターCT(ADCT)の有用性について検討するため、肺区域切除が予定された32例(男24例、女8例、平均67歳)にADCT検査を行い、従来の64列マルチディテクター(MDCT)と比較した。ADCTとMDCTで作成した三次元の肺血管構造画像に対し、2名の呼吸器外科専門医が切除区域に関する肺動脈と区域間肺静脈の可視化を5点満点で評価した。その結果、ADCTの評価点は平均4.4点、MDCTは3.9点と有意差を認めた。また肺動脈の存在についての診断能力のROC分析では、ADCTにおける曲線下面積(AZ=0.93)とMDCT(AZ=0.92)との間に有意差はなかった。各方法での確率スコアのための観察者間の一致に関しては、kappa値は0.70で、客観的な判定法として問題ないと考えられた。(株)オプトロニクス社, 2014, MEDICAL PHOTONICS, (16) (16), 9 - 14, Japanese[Refereed]Introduction scientific journal
- 肺手術前の高解像度3D-CTによる肺血管同定の有用性術前評価のための三次元シミュレーション画像作成において、320列エリアエリアディテクターCT(ADCT)の有用性について検討するため、肺区域切除が予定された32例(男24例、女8例、平均67歳)にADCT検査を行い、従来の64列マルチディテクター(MDCT)と比較した。ADCTとMDCTで作成した三次元の肺血管構造画像に対し、2名の呼吸器外科専門医が切除区域に関する肺動脈と区域間肺静脈の可視化を5点満点で評価した。その結果、ADCTの評価点は平均4.4点、MDCTは3.9点と有意差を認めた。また肺動脈の存在についての診断能力のROC分析では、ADCTにおける曲線下面積(AZ=0.93)とMDCT(AZ=0.92)との間に有意差はなかった。各方法での確率スコアのための観察者間の一致に関しては、kappa値は0.70で、客観的な判定法として問題ないと考えられた。(株)オプトロニクス社, Jan. 2014, Medical Photonics, (16号) (16号), 9 - 14, Japanese[Refereed]Introduction commerce magazine
- Nov. 2013, 胸部外科, 66(12) (12), 1038 - 1039, Japanese討論1[Refereed]Introduction scientific journal
- (株)メジカルビュー社, Aug. 2012, 臨床画像, 28(8) (8), 996 - 1003, Japaneseその検査、本当にそこまで必要ですか? 経過観察のストラテジー【第4回】 呼吸器・縦隔 腫瘍性疾患[Refereed][Invited]Introduction scientific journal
- (株)メジカルビュー社, Jul. 2012, 臨床画像, 28(7) (7), 786 - 794, Japanese【悪性腫瘍-その合理的な画像診断の進め方】 再発チェックを合理的に行うには 肺癌[Invited]Introduction scientific journal
- Feb. 2011, Thoracic cancer, Vol. 2, No. 1, pp. 7-15, EnglishApplication of hRad9 to lung cancer treatment as a molecular marker and a molecular target[Refereed]Introduction scientific journal
- Aug. 2008, 日本臨床, 66巻, 増刊6 肺癌, pp. 125-134, Japanese【肺癌 基礎・臨床研究のアップデート】 疫学・基礎研究 病態 肺癌とアポトーシスIntroduction scientific journal
- Feb. 2005, 肺癌, 45巻, 1号, pp. 63-73, Japanese肺癌の画像診断の基礎 CT・MRIの最新技術Introduction scientific journal
- Dec. 2003, 肺癌, 43巻, 7, pp. 818-825, Japanese肺癌の最新MRI診断Introduction scientific journal
- Others, Oncol Lett, Sep. 2014, EnglishClinical significance of the "not otherwise specified" subtype in candidates for resectable non-small cell lung cancer. / Clinical significance of the "not otherwise specified" subtype in candidates for resectable non-small cell lung cancer.Scholarly book
- Others, Surg Today, May 2014, EnglishSingle-incision thoracoscopic surgery using a chest wall pulley for lung excision in patients with primary spontaneous pneumothorax. / Single-incision thoracoscopic surgery using a chest wall pulley for lung excision in patients with primary spontaneous pScholarly book
- Others, Eur J Radiol, May 2014, EnglishDiffusion-weighted MR imaging vs. multi-detector row CT: Direct comparison of capability for assessment of management needs for anterior mediastinal solitary tumors. / Diffusion-weighted MR imaging vs. multi-detector row CT: Direct comparison of capabilitScholarly book
- 第31回日本内視鏡外科学会総会, Dec. 2018, Japanese, 博多, Domestic conference呼吸器悪性4 縦隔リンパ節郭清2[Invited]Invited oral presentation
- 第59回日本肺癌学会学術集会, Nov. 2018, Japanese, 東京, Domestic conference肺病変合併肺癌1Oral presentation
- 第39回日本レーザー医学会総会, Nov. 2018, Japanese, 東京, Domestic conference切除範囲の決定にAFIが有用であった気管分岐部切除を伴う左肺全摘術の1例Oral presentation
- 第80回日本臨床外科学会総会, Nov. 2018, Japanese, 東京, Domestic conference気管支断端瘻治療の考え方―安全な外科手術を目指して―Invited oral presentation
- 第70回日本気管食道科学会総会ならびに学術講演会, Nov. 2018, Japanese, 東京, Domestic conferenceSleeve pneumonectomyを行った2手術例の検討Oral presentation
- 第59回日本肺癌学会学術集会, Nov. 2018, English, 東京, Domestic conferenceJLCS/KASLC Joint SymposiumPublic discourse
- 第71回日本胸部外科学会定期学術集会, Oct. 2018, Japanese, 東京, Domestic conference肺癌2[Invited]Invited oral presentation
- 第54回日本医学放射線学会秋季大会, Oct. 2018, Japanese, 日本医学放射線学会, 福岡, Domestic conference縦隔発生の骨外性骨肉腫の一例Oral presentation
- 50th Annual Autumn Congress of the Korean Society for Thoraic & Cardiovascular Surgery, Oct. 2018, Japanese, Seoul, International conferenceSafe and less invasive thoracic surgery[Invited]Invited oral presentation
- 第16回 日本臨床腫瘍学会学術集会, Jul. 2018, Japanese, 神戸, Domestic conference非小細胞肺癌(非扁平上皮癌)完全切除症例に対するCDDP+PEMショートハイドレーション療法による術後補助化学療法の認容性試験Oral presentation
- 第108回肺癌学会関西支部会, Jun. 2018, Japanese, 大阪, Domestic conference肺性肥大性骨関節症を合併したROS1融合遺伝子陽性肺癌の一例Oral presentation
- 第61回関西胸部外科学会学術集会, Jun. 2018, Japanese, 名古屋, Domestic conference胸部発生の肉腫〜外科治療の限界を求めて〜[Invited]Invited oral presentation
- 第35回日本呼吸器外科学会総会・学術集会, May 2018, Japanese, 幕張, Domestic conference再発気胸[Invited]Invited oral presentation
- 第118回日本外科学会定期学術集会, Apr. 2018, Japanese, 東京, Domestic conference肺-集学的治療-2・その他Poster presentation
- European Lung Cancer Congress 2018, Apr. 2018, English, Geneva, International conferenceFeasibility study of adjuvant chemotherapy with cisplatin and pemetrexed short hydration regimen for completely resected non-small cell lung cancerOral presentation
- 第107回日本肺癌学会関西支部学術集会, Feb. 2018, Japanese, 日本肺癌学会関西支部学術集会, 大阪, Domestic conference胸腺類基底細胞癌の一例Oral presentation
- 第102回日本呼吸器内視鏡学会近畿支部会, Nov. 2017, Japanese, 日本呼吸器内視鏡学会近畿支部会, 大阪, Domestic conference当院における自然気胸に対する単孔式胸腔鏡下手術の検討Oral presentation
- 第58回日本肺癌学会学術集会, Oct. 2017, Japanese, 日本肺癌学会, 横浜, Domestic conference人工肺癌幹細胞を用いた、肺癌組織再構築と新規治療法開発の試みOral presentation
- 第58回日本肺癌学会学術集会, Oct. 2017, Japanese, 日本肺癌学会学術集会, 横浜, Domestic conference診断的治療目的に手術した後縦隔神経節細胞腫の3例Oral presentation
- 第58回日本肺癌学会学術集会, Oct. 2017, Japanese, 日本肺癌学会学術集会, 横浜, Domestic conference初発から15年の経過で肺転移を生じたgrade l髄膜腫の一例Poster presentation
- 第58回日本肺癌学会学術集会, Oct. 2017, Japanese, 日本肺癌学会学術集会, 横浜, Domestic conference左上区域に限局する転移性肺動脈腫瘍塞栓に対し外科的切除を行った1例Poster presentation
- 第58回日本肺癌学会学術集会, Oct. 2017, Japanese, 日本肺癌学会学術集会, 横浜, Domestic conference胸腺嚢胞に合併した胸腺癌の一切除例Poster presentation
- 第58回日本肺癌学会学術集会, Oct. 2017, Japanese, 日本肺癌学会学術集会, 横浜, Domestic conference気管支原生嚢胞からの発生が疑われた平滑筋肉腫の一切除例Poster presentation
- 第58回日本肺癌学会学術集会, Oct. 2017, Japanese, 日本肺癌学会学術集会, 横浜, Domestic conference気管支形成を伴う区域切除術を要した両側同時多発肺癌の手術例Oral presentation
- 第58回日本肺癌学会学術集会, Oct. 2017, Japanese, 日本肺癌学会学術集会, 横浜, Domestic conference右S2区域切除術後9年目に完全胸腔鏡下completion lobectomy を行った1例Oral presentation
- 第58回日本肺癌学会学術集会, Oct. 2017, Japanese, 日本肺癌学会学術集会, 横浜, Domestic conferenceポスター5 「希少症例1」Others
- 第70回日本胸部外科学会学術集会, Sep. 2017, Japanese, 日本胸部外科学会学術集会, 札幌, Domestic conferenceポスター(呼吸器21) 基礎実験1Others
- 第70回日本胸部外科学会学術集会, Sep. 2017, Japanese, 日本胸部外科学会学術集会, 札幌, Domestic conferencePropensity score matching 法を用いた高悪性度肺神経内分泌癌に対する補助化学療法の検討Oral presentation
- 第106回日本肺癌学会関西支部会, Jun. 2017, Japanese, 日本肺癌学会関西支部会, 大阪, Domestic conference嚢胞内に発生した肺線原発類基低細胞癌の一例Oral presentation
- 第27回日本サイトメトリー学会学術集会, Jun. 2017, Japanese, 日本サイトメトリー学会, 神戸, Domestic conference人工癌幹細胞と癌オルガノイドを用いた癌幹細胞研究[Invited]Nominated symposium
- 第60回関西胸部外科学会学術集会, Jun. 2017, Japanese, 関西胸部外科学会学術集会, 大阪, Domestic conference検診にて発見された後縦隔神経節細胞腫の1切除例Oral presentation
- 第60回関西胸部外科学会学術集会, Jun. 2017, Japanese, 関西胸部外科学会学術集会, 大阪, Domestic conference異なるアプローチにて鎖骨下動脈再建を行った肺尖部胸壁浸潤癌の2例Oral presentation
- 第106回日本肺癌学会関西支部会, Jun. 2017, Japanese, 日本肺癌学会関西支部会, 大阪, Domestic conference安全な胸腔鏡下肺葉切除術・縦隔リンパ節郭清のためにOthers
- 第60回関西胸部外科学会学術集会, Jun. 2017, Japanese, 関西胸部外科学会学術集会, 大阪, Domestic conferenceCase Presentation Award 16 呼吸器5Others
- 第34回日本呼吸器外科学会総会, May 2017, Japanese, 日本呼吸器外科学会総会, 福岡, Domestic conference要望演題14 呼吸器外科手術に おける教育、 トレーニングOthers
- 第34回日本呼吸器外科学会総会, May 2017, Japanese, 日本呼吸器外科学会総会, 福岡, Domestic conference続発性気胸に対する手術症例の検討Oral presentation
- 第34回日本呼吸器外科学会総会, May 2017, Japanese, 日本呼吸器外科学会, 福岡, Domestic conference人工肺癌幹細胞による、肺癌組織再構築の試みOral presentation
- 第34回日本呼吸器外科学会総会, May 2017, Japanese, 日本呼吸器外科学会総会, 福岡, Domestic conference術後横隔神経麻痺に対する横隔膜縫縮術の検討Poster presentation
- The 90th Annual Meetin of the Japanese Orthopaedic Association, May 2017, Japanese, The Japanese Orthopaedic Association, 仙台, Domestic conference骨軟部悪性腫瘍における肺転移切除例の治療成績Poster presentation
- 第34回日本呼吸器外科学会総会, May 2017, Japanese, 日本呼吸器外科学会総会, 福岡, Domestic conference血液透析患者に対する原発性肺癌手術症例の検討Poster presentation
- 第34回日本呼吸器外科学会総会, May 2017, Japanese, 日本呼吸器外科学会総会, 福岡, Domestic conference胸腺腫に関連した新規疾患概念、抗PIT-1 抗体症候群Oral presentation
- 第34回日本呼吸器外科学会総会, May 2017, Japanese, 日本呼吸器外科学会総会, 福岡, Domestic conference完全鏡視下手術手技を用いた拡大手術についての検討Oral presentation
- 第34回日本呼吸器外科学会総会, May 2017, Japanese, 日本呼吸器外科学会総会, 福岡, Domestic conference外科的切除によって著名な改善を認めた胸壁発生の腫瘍性低リン血症性軟骨化症の一例Poster presentation
- 第23回 呼吸器外科セミナー, May 2017, Japanese, 呼吸器外科セミナー, 福岡, Domestic conference外科医に必要な肺生理学の基礎知識Others
- 第34回日本呼吸器外科学会総会, May 2017, Japanese, 日本呼吸器外科学会総会, 福岡, Domestic conferenceVolume reductionにて症状が改善した縦隔原発骨外性骨肉腫の1例Poster presentation
- 第117回 日本外科学会定期学術集会, Apr. 2017, Japanese, 日本外科学会定期学術集会, 横浜, Domestic conferenceポスターセッション(146)「肺-診断」Others
- American Association for Cancer Research annual meeting 2017, Apr. 2017, English, American Association for Cancer Research, Washington D.C., USA, International conferenceInterleukin-6 blockade, a novel cancer stem cell targeted therapy, attenuates lung cancer tissue construction.Poster presentation
- International Joint Symposium in Kobe 2017 University of Washington University of Oslo and Kobe University, Mar. 2017, English, Kobe University, University of Washington, University of Oslo, 神戸, Malignant mesothelioma is a highly aggressive tumour originated from mesothelial cells of the pleura, pericardium or peritoneum. Among them, malignant pleural mesothelioma (MPM) is most common with increasing frequency throughout the world and closely related to exposure to asbestos. It can be classified histologically into epithelioid, sarcomatoid and biphasic types, among wh, International conferenceRole of Ror2 tyrosine kinase in ivasiveness of malignant pleural mesothelioma cells.Poster presentation
- 134. Kongresses der Deutschen Gesellschaft für Chirurgie, Mar. 2017, Japanese, Kongresses der Deutschen Gesellschaft für Chirurgie, ミュンヘン, ドイツ, International conferencePsf3 is a prognostic biomarker in lung adenocarcinoma:a larger trial using tissue microarrays of 864 consecutive resectionsOral presentation
- 第105回日本肺癌学会関西支部会, Feb. 2017, Japanese, 日本肺癌学会関西支部会, 大阪, Domestic conference縦隔原発骨外性骨肉腫の1例Oral presentation
- 第57回日本肺癌学会学術集会, Dec. 2016, Japanese, 日本肺癌学会, 福岡, Domestic conference病理組織診断で大細胞神経内分泌癌の中咽頭転移が判明した1例Oral presentation
- 第57回日本肺癌学会学術集会, Dec. 2016, Japanese, 日本肺癌学会, 福岡, Domestic conference肺結節切除標本内にびまん性特発性神経内分泌細胞過形成と多発tumorletを認めた1例Oral presentation
- 第57回日本肺癌学会学術集会, Dec. 2016, Japanese, 日本肺癌学会, 福岡, Domestic conference転移性脳腫瘍の発見から1年後に診断・手術に至ったpT1aN0M1bの原発性肺腺癌の1例Oral presentation
- 第57回日本肺癌学会学術集会, Dec. 2016, Japanese, 日本肺癌学会, 福岡, Domestic conference全身PET/MRI、MRI、PET/CT及び通常画像検査における胸腺上皮性腫瘍の病期診断能の比較Oral presentation
- 第57回日本肺癌学会学術集会, Dec. 2016, Japanese, 日本肺癌学会, 福岡, Domestic conference小細胞癌に対する外科的治療効果についての検討Oral presentation
- 第57回日本肺癌学会学術集会, Dec. 2016, Japanese, 日本肺癌学会, 福岡, Domestic conference次元CTコンピューター体積測定システムの臨床応用 経過観察CTによる良・悪性結節鑑別能評価Oral presentation
- 第57回日本肺癌学会学術集会, Dec. 2016, Japanese, 日本肺癌学会, 福岡, Domestic conference左上区域支入口部腫瘍に対して完全鏡視下左上区域切除術を行った1例Oral presentation
- 第57回日本肺癌学会学術集会, Dec. 2016, Japanese, 日本肺癌学会, 福岡, Domestic conference胸壁浸潤肺癌手術に対する低侵襲化への工夫Oral presentation
- 第57回日本肺癌学会学術集会, Dec. 2016, Japanese, 日本肺癌学会, 福岡, Domestic conference急速に増大し縦隔偏位をきたした肺癌合併巨大肺嚢胞の一例Oral presentation
- 第57回日本肺癌学会学術集会, Dec. 2016, Japanese, 日本肺癌学会, 福岡, Domestic conference完全胸腔鏡下における予防的気管支断端被覆症例の検討Oral presentation
- 第57回日本肺癌学会学術集会, Dec. 2016, Japanese, 日本肺癌学会, 福岡, Domestic conference右房内に進展した巨大浸潤性胸腺腫に対し人工心肺を用い完全切除可能であった1例Oral presentation
- 第57回日本肺癌学会学術集会, Dec. 2016, Japanese, 日本肺癌学会, 福岡, Domestic conference咽頭転移を生じた大細胞神経内分泌癌の1例Oral presentation
- 第57回日本肺癌学会学術集会, Dec. 2016, Japanese, 日本肺癌学会, 福岡, Domestic conference3次元肺癌CT検診用コンピューター支援診断システムの低線量化における再構成の影響に関する比較検討Oral presentation
- 第57回日本肺癌学会学術集会, Dec. 2016, Japanese, 日本肺癌学会, 福岡, Domestic conference3次元 CTコンピューター体積測定システムの臨床応用:経過観察CTによる良・悪性結節鑑別能評価Poster presentation
- 第20回日本気胸・嚢胞性肺疾患学会, Sep. 2016, Japanese, 日本気胸・嚢胞性肺疾患学会, 東京, Domestic conferencex Gateを用いた単孔式自然気胸手術の有用性の検討Oral presentation
- 第104回日本肺癌学会関西支部会, Jul. 2016, Japanese, 日本肺癌学会, 大阪, Domestic conference悪性黒色腫の肺転移と思われた1例Poster presentation
- 第33回日本呼吸器外科学会, May 2016, Japanese, 日本呼吸器外科学会, 京都, Domestic conference体細胞初期化因子導入による肺癌幹細胞誘導Oral presentation
- 第33回日本呼吸器外科学会, May 2016, Japanese, 日本呼吸器外科学会, 京都, Domestic conference周術期に感染性大動脈瘤を合併した降下性壊死性縦隔炎の1手術例Oral presentation
- 第33回日本呼吸器外科学会, May 2016, Japanese, 日本呼吸器外科学会, 京都, Domestic conference外傷性肺嚢胞に対して緊急手術を要した1例Oral presentation
- 第33回日本呼吸器外科学会, May 2016, Japanese, 日本呼吸器外科学会, 京都, Domestic conference右鎖骨下動脈再建を要した肺尖部胸壁浸潤癌の1切除例Oral presentation
- 第33回日本呼吸器外科学会, May 2016, Japanese, 日本呼吸器外科学会, 京都, Domestic conferencepT1N1非小細胞癌切除例におけるリンパ節病変の進展と予後に関する検討.Oral presentation
- 第33回日本呼吸器外科学会, May 2016, Japanese, 日本呼吸器外科学会, 京都, Domestic conference1cm以下微小肺癌切除例の検討Oral presentation
- 第198回近畿外科学会, Dec. 2015, Japanese, 近畿外科学会, 大阪, Domestic conference縦隔偏移をきたした巨大肺嚢胞の1切除例Oral presentation
- 第28回日本内視鏡外科学会総会, Dec. 2015, Japanese, 日本内視鏡外科学会総会, 大阪, Domestic conference呼吸器 悪性IOthers
- 第56回日本肺癌学会学術集会, Nov. 2015, Japanese, 日本肺癌学会学術集会, 横浜, Domestic conference胸腺腫瘍4Others
- CHST Annual Meeting2015, Oct. 2015, English, CHST, モントリオール, カナダ, International conferenceOncogenic Function of Psf3 in Non-Small Cell Lung CancerOral presentation
- 第58回関西胸部外科学会学術集会, Jun. 2015, Japanese, 関西胸部外科学会, 岡山, Domestic conferenceYIA(2):呼吸器Others
- EAES 2015(23rd Congress of the European of Endoscopic Surgery), Jun. 2015, English, 欧州内視鏡外科学会議, ブカレスト, ルーマニア, International conferenceValidity of thoracoscopic surgery for the resection of pulmonary metastasesPoster presentation
- 第32回日本呼吸器外科学会総会, May 2015, Japanese, 日本呼吸器外科学会, 高松, Domestic conference肺腺癌におけるCHFR(Checkpoint protein with forkhead and ring finger domain) 発現の意義Oral presentation
- 第115回日本外科学会定期学術集会, Apr. 2015, Japanese, 日本外科学会, 名古屋, Domestic conference肺・転移・再発Others
- 第66回日本気管食道科学会, Nov. 2014, Japanese, 日本気管食道科学会, 高知, Domestic conference気道狭窄をきたした食道神経鞘腫の1例Oral presentation
- 第73回日本癌学会学術集会, Sep. 2014, Japanese, 日本癌学会, 横浜, Domestic conference非小細胞肺癌におけるPsf3の役割についてOral presentation
- 第18回日本気胸・嚢胞性肺疾患学会総会, Sep. 2014, Japanese, 日本気胸・嚢胞性肺疾患学会, 福岡, Domestic conference胸腔鏡下自然気胸手術をより確実なものにするためのダブルレイヤー法の検討Oral presentation
- 第18回日本気胸・嚢胞性肺疾患学会総会, Sep. 2014, Japanese, 日本気胸・嚢胞性肺疾患学会, 福岡, Domestic conferencevon Willebrand’s diseaseを基礎疾患にもつ血気胸の1例Oral presentation
- 第100回日本肺癌学会関西支部会, Jun. 2014, Japanese, 日本肺癌学会関西支部, 大阪, Domestic conference神経線維腫症II型に伴った腫瘍破裂の1例Oral presentation
- ESTS, Jun. 2014, English, ヨーロッパ胸部外科学会, フランクフルト, ドイツ, International conferenceThe significant role of Necl-5 among patients with lung adenocarcinomaOral presentation
- 第31回日本呼吸器外科学会総会, May 2014, Japanese, 日本呼吸器外科学会, 東京, Domestic conference肺癌術後乾性嗽に対するトシル酸スプラタストの有用性の検討Oral presentation
- 第31回日本呼吸器外科学会総会, May 2014, Japanese, 日本呼吸器外科学会, 東京, Domestic conference高齢者肺葉切除症例early outcomeについてOral presentation
- 第31回日本呼吸器外科学会総会, May 2014, Japanese, 日本呼吸器外科学会, 東京, Domestic conference完全鏡視下で肺葉切除後の気管支断端被覆術の工夫Oral presentation
- ATS, May 2014, English, 米国胸部学会, サンフランシスコ, アメリカ, International conferenceRuptured Thymoma With Homothorax:A Case ReportPoster presentation
- 第114回日本外科学会定期学術集会, Apr. 2014, Japanese, 一般社団法人日本外科学会, 京都, Domestic conference当院における大腸癌肺転移切除症例の検討Poster presentation
- 第114回日本外科学会総会, Apr. 2014, Japanese, 日本外科学会, 京都, Domestic conference神経内分泌がんに対する補助化学療法に関する報告Oral presentation
- 第114回日本外科学会総会, Apr. 2014, Japanese, 日本外科学会, 京都, Domestic conference高齢者非小細胞肺癌に対する外科治療成績Oral presentation
- 第114回日本外科学会総会, Apr. 2014, Japanese, 日本外科学会, 京都, Domestic conferenceNOS(not otherwise specified)の臨床的意義Oral presentation
- ISHLC, Apr. 2014, English, 心肺移植学会, サンフランシスコ, アメリカ, International conferenceDual Ex Vivo Lung Perfusion Techniques Ameliorate Airway Hypoxia in Lung Grafts in RatsOral presentation
- GDCH, Mar. 2014, English, ドイツ外科学会, ベルリン, ドイツ, International conferenceAvailability of standardized thoracoscopic lobectomy for lung cancerOral presentation
- 第99回日本肺癌学会関西支部会, Feb. 2014, Japanese, 日本肺癌学会関西支部, 姫路, Domestic conference臍帯血移植前の消失しない肺浸潤影に対して胸腔鏡下肺葉切除を施行した一例Oral presentation
- 第54回日本肺癌学会総会, Nov. 2013, Japanese, 日本肺癌学会, 東京, Domestic conference高齢者非小細胞肺癌に対する外科治療成績Oral presentation
- 第54回日本肺癌学会総会, Nov. 2013, Japanese, 日本肺癌学会, 東京, Domestic conference高悪性度神経内分泌癌に対する手術症例の臨床的検討Oral presentation
- 第26回日本内視鏡学会, Nov. 2013, Japanese, 日本内視鏡学会, 福岡, Domestic conference胸腔鏡下肺部分切除術のこだわりと工夫-Endo GIA Radial ReloadOral presentation
- 第26回日本内視鏡学会, Nov. 2013, Japanese, 日本内視鏡学会, 福岡, Domestic conference完全鏡視下肺葉切除術における術後合併症、術後補助化学療法の忍容性について-開胸手術との比較Oral presentation
- 第66回日本胸部外科定期学術集会, Oct. 2013, Japanese, 日本胸部外科学会, 仙台, Domestic conference非小細胞肺癌切除例におけるNOS(not specific otherwise)の臨床的意義についてOral presentation
- 第66回日本胸部外科定期学術集会, Oct. 2013, Japanese, 日本胸部外科学会, 仙台, Domestic conference転移性肺腫瘍に対する胸腔鏡手術の有用性の検討Oral presentation
- The 49th Autumn Assembly of the Japan Radiological Society, Oct. 2013, Japanese, The Japan Radiological Society, 名古屋, Domestic conference巨大血腫と血胸を来した胸腺腫の1例Oral presentation
- The 51st Annual Meeting of Japan Society of Clinical Oncology, Oct. 2013, Japanese, Japan Society of Clinical Oncology, 京都, Domestic conference環境からのがんとその対応 アスベストと呼吸器癌 アスベスト関連肺癌に関してOral presentation
- ECCO_ESMO_ESTRO2013, Sep. 2013, English, ESMO, ブリュッセル, オランダ, International conferencePleural lavage cytology is a significant prognostic factor for stage I lung adenocarcinoma patientsPoster presentation
- ESTS 2013, Jun. 2013, English, ESTS, バーミンガム, イギリス, International conferenceThe efficacy of 320-detector row computed tomography for the assessment of preoperative pulmonary vasculature of candidates for pulmonary segmentectomyOral presentation
- 第30回日本呼吸器外科学会総会, May 2013, Japanese, 日本呼吸器外科学会, 名古屋, Domestic conference肺腺癌浸潤におけるNecl-5発現の意義に関する臨床および実験的検討Oral presentation
- 第30回日本呼吸器外科学会総会, May 2013, Japanese, 日本呼吸器外科学会, 名古屋, Domestic conference厳選ビデオ 胸腔鏡手術における不測の出血時の対応Oral presentation
- 第30回日本呼吸器外科学会総会, May 2013, Japanese, 日本呼吸器外科学会, 名古屋, Domestic conferenceSuccessful prolonged ex vivo lung perfusion for graft preservation in ratsOral presentation
- 第30回日本呼吸器外科学会総会, May 2013, Japanese, 日本呼吸器外科学会, 名古屋, Domestic conferenceVATS自然気胸手術をより確実なものにするための当科での工夫Oral presentation
- 第30回日本呼吸器外科学会総会, May 2013, Japanese, 日本呼吸器外科学会, 名古屋, Domestic conferenceThe role of Necl-5 in the invasive activity of lung adenocarcinomaOral presentation
- 第30回日本呼吸器外科学会総会, May 2013, Japanese, 日本呼吸器外科学会, 名古屋, Domestic conferencePsf3は肺腺癌における予後を判定する新しいバイオマーカーであるOral presentation
- 第113回日本外科学会, Apr. 2013, Japanese, 日本外科学会, 福岡, Domestic conference肺腺癌浸潤におけるNecl-5の働きについての検討Oral presentation
- 第113回日本外科学会, Apr. 2013, Japanese, 日本外科学会, 福岡, Domestic conference肺腺癌における予後因子としてのNectin-3の発現についてOral presentation
- 第113回日本外科学会, Apr. 2013, Japanese, 日本外科学会, 福岡, Domestic conference肺腺癌におけるPSF3発現の臨床的意義の検討Oral presentation
- 第113回日本外科学会, Apr. 2013, Japanese, 日本外科学会, 福岡, Domestic conferenceがん細胞の浸潤転移機構の解明と治療への展開 肺腺癌浸潤におけるNecl-5の働きについての検討Oral presentation
- 第5回日本呼吸機能イメージング研究会学術集会, Jan. 2013, Japanese, 日本呼吸機能イメージング研究会, 徳島, Domestic conference吸気呼気CTによる肺気腫の定量評価Poster presentation
- 53th Annual Meeting of The Japan Lung Cancer Society, Nov. 2012, Japanese, The Japan Lung Cancer Society, 岡山, Domestic conferenceUtility of Whole-Body Contrast-Enhanced Quick 3D for Distance Metastasis and Recurrence Assessment in Lung Cancer PatientsOral presentation
- 第53回日本肺癌学会総会, Nov. 2012, Japanese, The Japan Lung Cancer Society, 岡山, Domestic conference当科における傍腫瘍性神経症候群合併小細胞肺癌の臨床的検討Poster presentation
- 第53回日本肺癌学会総会, Nov. 2012, Japanese, The Japan Lung Cancer Society, 岡山, Domestic conferenceALK染色陽性肺腺癌の術前診断の可能性Poster presentation
- 53th Annual Meeting of The Japan Lung Cancer Society, Nov. 2012, Japanese, The Japan Lung Cancer Society, 岡山, Domestic conferenceAdaptive Iterative Dose Reduction using Three Dimensional Processing (AIDR 3D) for Radiation Dose Reduction for Chest CT ExaminationOral presentation
- 第48回日本医学放射線学会秋季臨床大会, Sep. 2012, Japanese, Japan Radiological Society, 長崎, Domestic conference術待機中に空洞形成を伴った非定型的肺カルチノイドの一例Poster presentation
- 71th annual congress of Japanese Cancer Association, Sep. 2012, English, Japan Cancer Association, 札幌, Domestic conferenceSirt1 is a tumor promoter in lung adenocarcinomaOral presentation
- Amarican Thoracic Society Internatinal Conference 2012, May 2012, English, Amarican Thoracic Society, San Francisco, USA, Epithelial-Mesenchymal Transition (EMT) has been classified as a unique process by which epithelial cells undergo mesenchymal phenotype leading to increased motility and invasion. The aim of this study was to elucidate the biological functions of Slug/Sna, International conferenceSlug Increases Sensitivity To Tubulin Binding Agents Via The Downregulation Of Beta III And IVa-Tubulin In Lung Cancer CellsPoster presentation
- 第52回肺癌学会総会, Nov. 2011, Japanese, 肺癌学会, 大阪, Domestic conference非小細胞肺癌リンパ節転移の定量的診断能; 3T-MRI STIR vs. 1.5T-MRI STIR vs. PET/CTPoster presentation
- 第52回日本肺癌学会総会, Nov. 2011, Japanese, 日本肺癌学会, 大阪, Domestic conferenceQuantitative Perfusion CT using 320-Detector Row CT: Differentiation of Malignant from Benign Nodules as Compared with Dynamic MRI and PET/CTOral presentation
- 第51回肺癌学会総会, Nov. 2010, Japanese, 日本肺癌学会, 広島, Domestic conferenceFDG-PET/CTにて異常集積を認めた混合性胚細胞腫瘍の一例Poster presentation
- 第17回関西転移性肺腫瘍研究会, Mar. 2010, Japanese, 大阪, Domestic conference転移性肺腫瘍に対する放射線治療後のサルベージ手術Oral presentation
- 第42回兵庫呼吸器外科研究会, Mar. 2010, Japanese, 神戸, Domestic conference頚部から胸腔内に及ぶ巨大desmoidの1切除例Oral presentation
- 第22回近畿胸腔鏡研究会, Mar. 2010, Japanese, 日本呼吸器外科学会, 京都, Domestic conference胸腔鏡下区域切除術における区域間処理の工夫Oral presentation
- 第105回兵庫県肺癌懇話会, Mar. 2010, Japanese, 神戸, Domestic conferencecT1N3M0原発性肺癌を疑い、診断目的に切除した肺腫瘤の1例Oral presentation
- 第91回日本肺癌学会関西支部会, Jan. 2010, Japanese, 日本肺癌学会, 大津, Domestic conference胸腔鏡下に切除した後縦隔発生Castleman病の1例Oral presentation
- 第104回兵庫県肺癌懇話会, Dec. 2009, Japanese, 神戸,, Domestic conference肺結核合併肺癌の1手術例Oral presentation
- 第50回日本肺癌学会総会, Nov. 2009, Japanese, 日本肺癌学会, 東京, Domestic conference肺腺癌におけるNecl-5発現の意義Poster presentation
- 第10回近畿呼吸器外科手術手技研究会, Nov. 2009, Japanese, 大阪, Domestic conference左側肺癌リンパ節郭清Oral presentation
- 第50回日本肺癌学会総会, Nov. 2009, Japanese, 日本肺癌学会, 東京, Domestic conference320列面検出器CTによるFirst-Pass Perfusion CT vs. FDG-PET/CT: 肺結節の良・悪性鑑別診断能に関する検討Oral presentation
- 第62回日本胸部外科学会定期学術集会, Oct. 2009, Japanese, 日本胸部外科学会, 横浜, Domestic conference広汎な胸壁浸潤をきたしたSeperior sulcus tumorに対する前方(trans-manubrial)・後方アプローチの有用性Oral presentation
- 14th World Congress on Advances in Oncology, Oct. 2009, English, ロートラキ, ギリシャ, International conferenceDNA damage sensor protein hRad9 - A novel molecular target for lung cancer treatment[Invited]Invited oral presentation
- 第90回日本肺癌学会関西支部会, Jul. 2009, Japanese, 日本肺癌学会, 大阪, Domestic conferenceB型肝炎性肝細胞癌にて肝移植後に発症した転移性肺腫瘍に対する1手術例Oral presentation
- 第52回関西胸部外科学会学術集会, Jun. 2009, Japanese, 日本胸部外科学会, 岡山, Domestic conferenceModified hemi-clamshell approachによるChronic expanding hematomaの1手術例Oral presentation
- 第26回日本呼吸器外科学会総会, May 2009, Japanese, 日本呼吸器外科学会, 北九州, Domestic conference断端再発のリスクを考慮した部分切除術法(露天掘り法)Poster presentation
- 第26回日本呼吸器外科学会総会, May 2009, Japanese, 日本呼吸器外科学会, 北九州, Domestic conference原発性肺線癌におけるNecl-5発現の検討Poster presentation
- 第9回近畿呼吸器外科手術手技研究会, Apr. 2009, Japanese, 大阪, Domestic conference下降性壊死性縦隔炎に対する経胸腔アプローチによる縦隔ドレナージ術Oral presentation
- 第109回日本外科学会定期学術集会, Apr. 2009, Japanese, 日本外科学会, 福岡, Domestic conferenceDamage repair pathwayにおけるNon-synonymous SNPsと肺腺癌の発生についての検討Poster presentation
- 第49回日本肺癌学会総会, Nov. 2008, Japanese, 日本肺癌学会, 北九州, Domestic conference非小細胞肺癌患者における全身FDG-PET/CTの術後再発診断能に関する検討Oral presentation
- 第49回 日本肺癌学会総会, Nov. 2008, Japanese, 日本肺癌学会, 北九州市, Domestic conference胸部MRIにおける肺腺癌の結節同定能と組織分類の検討 拡散強調像とSTIR像の比較Oral presentation
- 第49回日本肺癌学会総会, Nov. 2008, Japanese, 日本肺癌学会, 北九州, Domestic conferenceDynamic MRI vs. CT vs. RI:非小細胞肺癌患者の術後肺機能予測能に関する検討Poster presentation
- •第49回 日本肺癌学会総会, Nov. 2008, Japanese, 日本肺癌学会, 北九州市, Domestic conferenceDynamic MRI vs.CT vs.RI 非小細胞肺癌患者の術後肺機能予測能に関する検討Oral presentation
- 第61回 日本胸部外科学会定期学術集会, Oct. 2008, Japanese, 日本胸部外科学会, 福岡, Domestic conference悪性胸膜中皮腫の外科治療:手術成績と今後の戦略Public symposium
- Chest 2008, Oct. 2008, English, American College of Chest Physician, フィラデルフィア, 米国, International conferenceThe interval for re-evaluation of foci is necessary prior to pulmonary metastasectomyPoster presentation
- 第61回 日本胸部外科学会定期学術集会, Oct. 2008, Japanese, 日本胸部外科学会, 福岡, Domestic conferencePoor Risk肺癌症例に対するSub-lobar Resectionの妥当性Oral presentation
- 第88回 日本肺癌学会関西支部会, Jul. 2008, Japanese, 日本肺癌学会, 大阪, Domestic conference腫瘍随伴性小脳変性症(PCD)を合併した小細胞肺癌の1例Oral presentation
- 第51回 関西胸部外科学会学術集会, Jun. 2008, Japanese, 日本胸部外科学会, 富山, Domestic conference下降性壊死性縦隔炎に対する頚部切開および開胸による縦隔ドレナージPublic symposium
- 第25回 日本呼吸器外科学会総会, May 2008, Japanese, 日本呼吸器外科学会, 宇都宮, Domestic conference非小細胞肺癌におけるFOXO1発現の意義Poster presentation
- 第25回 日本呼吸器外科学会総会, May 2008, Japanese, 日本呼吸器外科学会, 宇都宮, Domestic conference転移性肺腫瘍に対する粒子線治療後のサルベージ手術Poster presentation
- 第25回 日本呼吸器外科学会総会, May 2008, Japanese, 日本呼吸器外科学会, 宇都宮, Domestic conference下降性壊死性縦隔炎に対する徹底的な縦隔ドレナージ術Oral presentation
- 第99回 兵庫肺癌懇話会, Mar. 2008, Japanese, 神戸, Domestic conference腫瘍随伴性小脳変性症(PCD)を合併した小細胞肺癌の1例Oral presentation
- 第48回日本肺癌学会総会, Nov. 2007, Japanese, 日本肺癌学会, 名古屋, Domestic conference放射線診断と治療の最前線 肺癌患者におけるM因子診断における全身脂肪抑制併用拡散強調画像の有用性に関する検討[Invited]Invited oral presentation
- 第48回日本肺癌学会総会, Nov. 2007, Japanese, 日本肺癌学会, 名古屋, Domestic conference非造影MRIを用いた肺末梢結節スクリーニング能の検討Oral presentation
- 第48回日本肺癌学会総会, Nov. 2007, Japanese, 日本肺癌学会, 名古屋, Domestic conferenceAssessement of Non-contrast-enhanced MRI for Lung Cancer ScreeningOral presentation
- 第48回日本肺癌学会総会, Nov. 2007, Japanese, 日本肺癌学会, 名古屋, Domestic conference非小細胞肺癌患者の術後肺機能予測に関する検討:Perfusion MRI,造影MSCT及び肺血流SPECTの対比Poster presentation
- 第48回日本肺癌学会総会, Nov. 2007, Japanese, 日本肺癌学会, 名古屋, Domestic conference非小細胞肺癌患者の術後肺機能予測に関する検討 Dynamic Perfusion MRI、MDCT及び肺血流SPECTの対比Poster presentation
- 第48回日本肺癌学会総会, Nov. 2007, Japanese, 日本肺癌学会, 名古屋, Domestic conference肺癌患者におけるM因子診断における全身脂肪抑制併用拡散強調画像の有用性に関する検討Public symposium
- 第48回日本肺癌学会総会, Nov. 2007, Japanese, 日本肺癌学会, 名古屋, Domestic conference肺癌の肺門部気管支血管周囲組織浸潤と断端および予後に関する検討(続報)Poster presentation
- 第48回日本肺癌学会総会, Nov. 2007, Japanese, 日本肺癌学会, 名古屋, Domestic conference術後補助化学療法としてのCDDP+VNRの安全性と有用性の検討Poster presentation
- 第48回日本肺癌学会総会, Nov. 2007, Japanese, 日本肺癌学会, 名古屋, Domestic conference悪性胸膜中皮腫(MPM)手術例の検討Public symposium
- 第48回日本肺癌学会総会(名古屋), Nov. 2007, Japanese, 日本肺癌学会, 名古屋, Domestic conferencePET/CTによる非小細胞肺癌術後患者の再発予測Public symposium
- 第48回日本肺癌学会総会, Nov. 2007, Japanese, 日本肺癌学会, 名古屋, Domestic conferenceFDG-PETの意義と応用 非小細胞肺癌術後患者における切除断端部再発 FDG-PET/CTと造影CTの診断能比較Public symposium
- 第48回日本肺癌学会総会, Nov. 2007, Japanese, 日本肺癌学会, 名古屋, Domestic conferenceFDG-PETの意義と応用 PET/CTによる非小細胞肺癌術後患者の再発予測Public symposium
- 第48回日本肺癌学会総会, Nov. 2007, Japanese, 日本肺癌学会, 名古屋, Domestic conferenceBAC cell浸潤におけるTumor-host interfaceの役割に関しての実験的検討Others
- 第60回日本胸部外科学会総会, Oct. 2007, Japanese, 日本胸部外科学会, 仙台, Domestic conferencePoor risk肺癌症例に対する縮小手術の妥当性Oral presentation
- Chest2007, Oct. 2007, English, American College of Chest Physicians, シカゴ, 米国, International conferenceIn-vitro visualization of cancer-stroma interaction in bronchiolo-alveolar carcinoma with invasive componentPublic symposium
- 第66回日本癌学会総会, Oct. 2007, Japanese, 日本癌学会, 横浜, Domestic conferenceIn-vitro visualization of cancer-stroma interaction in bronchiolo-alveolar carcinoma (BAC) with invasive componentPoster presentation
- 第69回日本呼吸器学会近畿地方会, Jun. 2007, Japanese, 日本呼吸器学会近畿支部, 大阪, Domestic conference大量喀血を契機に発見された肺肉腫様癌の1例Oral presentation
- 第24回日本呼吸器外科学会総会, May 2007, Japanese, 日本呼吸器外科学会, 横浜, Domestic conference原発性気管癌に対して緊急手術を施行した2例Oral presentation
- 第24回日本呼吸器外科学会総会, May 2007, Japanese, 日本呼吸器外科学会, 横浜, Domestic conference家族性多発性内分泌腺腫症の精査中に巨大縦隔腫瘍を指摘され胸腺カルチノイドと診断された一例Poster presentation
- 第24回日本呼吸器外科学会総会, May 2007, Japanese, 日本呼吸器外科学会, 横浜, Domestic conference右主気管支内腔を鋳型状に発育・閉塞した右下葉原発筋上皮癌の1例Poster presentation
- CHEST2006, Oct. 2006, English, American College of Chest Physician, Solt Lake City, Utah, USA, International conferenceChemosensitivity of lung cancer: difference between primary tumor and metastatic lymph nodePoster presentation
- 第64回日本癌学会総会, Sep. 2005, Japanese, 日本癌学会, 札幌, Domestic conference肺癌におけるDNA damage sensor蛋白Rad9発現の意義Poster presentation
- 日本肺癌学会関西支部会(第82回), Jul. 2005, Japanese, 日本肺癌学会, 神戸, Domestic conference孤立性肺転移で発見された不顕性甲状腺乳頭癌の1例Oral presentation
- 第94回日本病理学会総会, Apr. 2005, Japanese, 日本病理学会, 横浜, Domestic conference転写調節因子による腫瘍の表現形質と悪性度の修飾 細胞周期制御蛋白p21およびその転写活性化因子の発現異常 肺腺癌における表現形質と悪性度の変化Public symposium
- 第94回日本病理学会総会, Apr. 2005, Japanese, 日本病理学会, 横浜, Domestic conference細胞周期制御蛋白p21およびその転写活性化因子の発現異常-肺腺癌における表現形質と悪性度の変化Public symposium
- 第45回日本肺癌学会総会, Nov. 2004, Japanese, 横浜, Domestic conference原発性肺腺癌におけるp53発現異常と細胞分裂能の関連性Oral presentation
- 第45回日本肺癌学会総会, Nov. 2004, Japanese, 日本肺癌学会, 横浜, Domestic conferenceSTIR Turbo SE MRI vs. FDG-PET: 非小細胞肺癌における術前転移リンパ節診断能の比較Oral presentation
- 2004.10.25 第45回日本肺癌学会総会(横浜), Oct. 2004, Japanese, 日本肺癌学会, 横浜, Domestic conferenceMRIによる肺癌検診の有用性に関する検討Oral presentation
- 第63回日本癌学会総会, Sep. 2004, Japanese, 日本癌学会, 福岡, Domestic conferencehRad9蛋白質の生物学的特性と癌細胞における機能Poster presentation
■ Research Themes
- 学術研究助成基金助成金/基盤研究(C), Apr. 2018 - Mar. 2021Competitive research funding
- 学術研究助成基金助成金/基盤研究(C), Apr. 2018 - Mar. 2021Competitive research funding
- 科学研究費補助金/基盤研究(B), Apr. 2017 - Mar. 2020, Principal investigatorCompetitive research funding
- 学術研究助成基金助成金/基盤研究(C), Apr. 2015 - Mar. 2018Competitive research funding
- 科学研究費補助金/基盤研究(B), Apr. 2014 - Mar. 2017, Principal investigatorCompetitive research funding
- 学術研究助成基金助成金/基盤研究(C), Apr. 2014 - Mar. 2017Competitive research funding
- 科学研究費補助金/基盤研究(C), Apr. 2012 - Mar. 2015Competitive research funding
- 学術研究助成基金助成金/基盤研究(C), 2011, Principal investigatorCompetitive research funding
- 科学研究費補助金/基盤研究(C), 2008, Principal investigatorCompetitive research funding
- 科学研究費補助金/基盤研究(C), 2006, Principal investigatorCompetitive research funding
- 科学研究費補助金/萌芽研究, 2006Competitive research funding
- 科学研究費補助金/基盤研究(B), 2005Competitive research funding
- 科学研究費補助金/基盤研究(C), 2005, Principal investigatorCompetitive research funding