村山 留美子 | ![]() |
ムラヤマ ルミコ | |
大学院人間発達環境学研究科 人間環境学専攻 | |
准教授 | |
社会・自然科学関係 |
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研究論文(学術雑誌)
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研究論文(学術雑誌)
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研究論文(学術雑誌)
Purpose: We investigated the purpose and the motivation for the future practice of physical activity and related factors in Japanese university students. Materials and Methods: The participants were 499 university students (407 men and 92 women). Participants were surveyed using an anonymous self-administered questionnaire. Questionnaire items were anthropometrics, current exercise habits, preference for exercise, existence of exercise partners, benefits of exercise, self-efficacy for exercise, and the purpose to be motivated to exercising in the future. Results: The exercise group had higher scores for preference for exercise, exercise partners, self-efficacy for exercise, and benefits of exercise than the non-exercise group. The exercise group also reported being more likely to be motivated to exercise in the future than the nonexercise group. In the exercise group, those who felt benefits of exercise were more likely to be motivated to exercise for enhancement of health, enjoyment, making friends, prevention of illness, and enhancement of competitiveness. In the non-exercise group, those who had a preference for exercise were more likely to be motivated to exercise in the future for enjoyment, prevention of illness, and enhancement of competitiveness. In both the exercise and non-exercise groups, women were markedly more likely to be motivated to exercise in the future for aesthetics. Conclusions: These results indicate that there is a difference in the purpose and the motivation for future practice of physical activity between the exercise group and the non-exercise group as well as between genders.
UNIV ALICANTE, 2018年07月, J Hum Health Sport Exerc, 14 (1), 61 - 74, 英語[査読有り]
研究論文(学術雑誌)
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研究論文(大学,研究機関等紀要)
In Japan, the lifetime cancer risk level of 10-5 is used to set the ambient air quality standard for benzene, which is a well-established cause of cancer in humans. This study assessed the "acceptable" risk level for the Japanese public aged 20–59 years regarding atmospheric carcinogen(s). Results of face-to-face questionnaire surveys conducted in 2014 indicated that more than half the respondents selected annual cancer risk level of "one in one million" or over as "acceptable". Five percent of respondents demanded "zero-risk", and twenty percent did not answer their "acceptable risk level" for atmospheric carcinogen(s). Moreover, the results of investigations conducted from 1999 through 2014 suggest that the acceptable risk levels for carcinogenic substances in the air have tended to increase over time.
一般社団法人日本リスク研究学会, 2016年, 日本リスク研究学会誌, 26 (2), 76 - 76, 日本語[査読有り]
研究論文(学術雑誌)
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Various metals produced from human activity are ubiquitously detected in ambient air. The metals may lead to induction and/or exacerbation of respiratory diseases, but the significant metals and factors contributing to such diseases have not been identified. To compare the effects of each metal and different oxidation states of metals on human airway, we examined the viability and production of interleukin (IL)-6 and IL-8 using BEAS-2B cell line, derived from human airway epithelial cells. Airway epithelial cells were exposed to Mn2+, V4+, V5+, Cr3+, Cr6+, Zn2+, Ni2+, and Pb2+ at a concentration of 0.5, 5, 50, or 500 mol/L for 24 hours. Mn and V decreased the cell viability in a concentration-dependent manner, and V5+ tended to have a greater effect than V4+. The Cr decreased the cell viability, and (Cr+6) at concentrations of 50 and 500 mol/L was more toxic than (Cr+3). Zn at a concentration of 500 mol/L greatly decreased the cell viability, whereas Ni at the same concentration increased it. Pb produced fewer changes. Mn and Ni at a concentration of 500 mol/L induced the significant production of IL-6 and IL-8. However, most of the metals including (V+4, V+5), (Cr+3, Cr+6), Zn, and Pb inhibited the production of both IL-6 and IL-8. The present results indicate that various heavy metals have different effects on toxicity and the proinflammatory responses of airway epithelial cells, and those influences also depend on the oxidation states of the metals.
SAGE PUBLICATIONS INC, 2015年03月, INTERNATIONAL JOURNAL OF TOXICOLOGY, 34 (2), 195 - 203, 英語[査読有り]
研究論文(学術雑誌)
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The effects of environmental pollutants on airway clearance have not been well elucidated. This study examined mucociliary transport using different sized-fluorescent particles on polarized human airway epithelial cells which were maintained in an air-liquid interface (ALI) culture system. The effects of hydrogen peroxide (H2O2) exposure on mucociliary transport were also investigated. The movement of fluorescent particles with diameters of 10-14 and 2.5-4.5 mm was observed by fluorescent microscopy as an index of the mucociliary transport. The mixture of the particles with two different sizes was propelled concentrically on the apical surface by the interaction of ciliary activity and mucus in the control condition, whereas H2O2 exposure for 24 h significantly inhibited the movement of the particles. The particle sizes did not affect their movement after the control or H2O2 exposure. These results suggest that particle tracking on polarized human airway epithelial cells is a useful experimental tool for the evaluation of the effect of environmental pollutants on mucociliary transport. In addition, reactive oxygen species may impair mucociliary transport, leading to the airway damage and exacerbation of respiratory diseases.
INFORMA HEALTHCARE, 2014年03月, TOXICOLOGY MECHANISMS AND METHODS, 24 (3), 191 - 195, 英語[査読有り]
研究論文(学術雑誌)
Epidemiologic studies have reported that Asian sand dust (ASD) particles can affect respiratory health; however, the mechanisms remain unclear. We investigated the effects of ASD on airway epithelial cells and immune cells, and their contributing factors to the effects. Human airway epithelial cells were exposed to ASD collected on 1-3 May (ASD1) and on 12-14 May (ASD2) 2011 in Japan and heat-treated ASD1 for excluding heat-sensitive substances (H-ASD) at a concentration of 0, 3, 30 or 90 mu gml(-1) for 4 or 24h. Furthermore, bone marrow-derived dendritic cells (BMDC) from atopic prone mice were differentiated by culture with granulocyte-macrophage colony-stimulating factor (GM-CSF) then these BMDC were exposed to the ASD for 24h. Also splenocytes as mixture of immune cells were exposed to the ASD for 72h. All ASD dose dependently reduced viability of airway epithelial cells. Non-heated ASD showed a dose-dependent increase in the protein release of interleukin (IL)-6 and IL-8. The raises induced by ASD1 were higher than those by ASD2. ASD1 and ASD2 also elevated ICAM-1 at the levels of mRNA, cell surface protein and soluble protein in culture medium. In contrast, H-ASD did not change most of these biomarkers. Non-heated ASD showed enhancement in the protein expression of DEC205 on BMDC and in the proliferation of splenocytes, whereas H-ASD did not. These results suggest that ASD affect airway epithelial cells and immune cells such as BMDC and splenocytes. Moreover, the difference in ASD events and components adhered to ASD can contribute to the health effects. Copyright (c) 2013 John Wiley & Sons, Ltd.
WILEY-BLACKWELL, 2014年03月, JOURNAL OF APPLIED TOXICOLOGY, 34 (3), 250 - 257, 英語[査読有り]
研究論文(学術雑誌)
Although epidemiological studies have demonstrated that cedar pollen influences respiratory health, effective method for inactivating cedar pollen has not been established. Streamer discharge is a type of plasma discharge in which high-speed electrons collide with oxygen and nitrogen molecules. It reportedly has the ability to eliminate bacteria, mould, chemical substances and allergens. The present study investigated the influence of pollen on BEAS-2B cell line, derived from human airway epithelial cells, as well as the efficiency of streamer discharge on pollen-induced health effects. Airway epithelial cells were exposed to non-treated pollen and streamer-discharged pollen at doses of 100 and 1000 μg/mL for 6 or 24 h. Non-treated pollen at a dose of 1000 mg/mL significantly decreased cell viability and induced both mRNA and protein expression of interleukin-6, whereas streamer-discharged pollen showed the attenuated changes as compared with non-treated pollen. Further, scanning electron micrographs showed that streamer discharge caused the fine structural changes of pollen. These results provide the first experimental evidence that pollen at a high dose affects cell viability and inflammatory responses, and streamer discharge technology attenuates their influences by decomposing pollen. © 2013 by the Society for Experimental Biology and Medicine.
2013年02月, Experimental Biology and Medicine, 238 (2), 187 - 192, 英語[査読有り]
研究論文(学術雑誌)
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2020年度の本研究は、新型コロナウィルスの感染拡大の影響に伴い、計画通りには研究を実施できなかった。全ての対話実践、学会報告、シンポジウムがオンラインでの開催となり、研究代表者、研究分担者たちは暗中模索の状態でそれぞれの研究活動を続けた。2020年度は以下の5つの対話実践・研究を遂行した。
①大学院のオンライン対話を使った授業実践とその考察、②不登校と哲学プラクティスをテーマにしたシンポジウムの開催、③社会規範をテーマにした対話実践、④釜ヶ崎(あいりん地区)の変容するコミュニティの中で多様性を考えるためのイベント、⑤コロナ禍におけるマイノリティ当事者の不安.心配に関するオンライン調査
研究代表者の稲原と分担者の中川・津田は、①を行い、その実践報告を日本哲学プラクティス連絡会第6回大会で発表した。②に関しては、稲原と中川は2021年1月30日にオンライン・シンポジウム「不登校と哲学プラクティス」を企画し、開催した。不登校支援をしている実践者や不登校を経験した当事者に登壇していただき、一般参加者たちと共にこのテーマをめぐる様々な問題について議論できた。③については、研究分担者の梶谷と稲原がそれぞれオンライン哲学カフェや対話イベントを企画し、運営している。梶谷に関しては、本研究と関連するものだけでも8つの哲学カフェや対話イベントを開催した。稲原に関していうと、3回のオンライン哲学カフェを開催した。研究分担者の高橋とほんまは、④のイベント「カマは燃えている/ ココ〈ボール〉ルームでなりたい自分になる~あらためて"多様性"をかんがえる連続企画」の企画・運営に携わり、イベントの司会進行役などを担当した。最後に、研究分担者の村山は、リスク学の見地からコロナ禍のマイノリティ当事者の不安・心配を明らかにするために、オンライン調査を実施した。この調査結果をもとに、哲学対話のテーマ決めを行う。
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